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1

Babatunde Abiodun Kelly. "Insecticidal potency of entomopathogenic bacterium Bacillus subtilis on cockroach (Periplaneta americana)." International Journal of Science and Research Archive 12, no. 1 (2024): 934–39. http://dx.doi.org/10.30574/ijsra.2024.12.1.0839.

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The effect of exposing cockroaches to entomopathogenic bacteria isolated from the diseased specie was examined based on established parameters. Cockroaches were collected from residential areas in Akure metropolis in Nigeria using a bread and beer trap, brought to the laboratory, housed in wooden cages with wire nettings, provided with starch-based food and sterile water. Collected cockroaches were observed for the onset of possible disease symptoms amongst the population for several weeks. Resulting moribund and dead cockroaches were aseptically picked, surface sterilized and homogenized insi
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Pakina, Elena N., Sergey I. Shkurkin, and Maria T. Mukhina. "Effectiveness of biological products for control of the most significant mycoses on potato crops." RUDN Journal of Agronomy and Animal Industries 18, no. 4 (2023): 501–7. http://dx.doi.org/10.22363/2312-797x-2023-18-4-501-507.

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Experiments on comparative assessment of effectiveness of bioagents to control the most significant fungal diseases were carried out on crops of potato breeding line in the Zernograd district, Rostov region. Biofungicide Metabakterin, WP based on Methylobacterium extorquens NVD VKM B-2879D + Validamycin Streptomyces hygroscopicus subsp. limoneus VKPM AC-1966 + Bacillus subtilis VKPM B-2918 IPM 215 and biofungicide Vitaplan based on Bacillus subtilis , strain VKM-B-2604D + Bacillus subtilis , strain VKM-B-2605D were studied in the research. The results showed that Metabakterin, WP at the rate o
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3

Avdeenko, A. P., and S. S. Avdeenko. "The effect of treatment of various strains of Bacillus subtilis on the productivity of winter wheat." IOP Conference Series: Earth and Environmental Science 979, no. 1 (2022): 012026. http://dx.doi.org/10.1088/1755-1315/979/1/012026.

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Abstract In the conditions of the Rostov region of the Russian Federation on ordinary micellar-carbonate chernozems, the effect of Bacillus subtilis strains during the processing of winter wheat seeds on the productivity and quality of grain of the zoned varieties Grom and Kalym was studied. The issues of influence of strains 10-VISR, IPM 215, VKM-V-2605D and 26D on field germination of seeds, winter hardiness and survival of plants for harvesting are considered. The analysis of the dependence of the structure of the yield and the yield of wheat varieties on the Bacillus subtilis strain is giv
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Fauzi, Irfan, and Soekadar Wiryadiputra. "Population of Pratylenchus coffeae (Z.) and growth of Arabica coffee seedling inoculated by Pseudomonas diminuta L. and Bacillus subtilis (C.)." Pelita Perkebunan (a Coffee and Cocoa Research Journal) 31, no. 1 (2015): 30–40. http://dx.doi.org/10.22302/iccri.jur.pelitaperkebunan.v31i1.77.

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AbstractPratylenchus coffeae is a parasitic nematoda that infected the roots of some plants, one of them is coffee. The Infection of Pratylenchus coffeae cause root tissue damage that led to root lession and make root become rotten, it will interfere the ability of roots to absorb water and nutrients in the soil which resulted in the growth of plants. At the moment, control of Pratylenchus coffeae are following integrated pests management (IPM) program, which integrated between the use of coffee resistant clone and application of biological agents. Research on biological control was conducted
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Shen, Wenqiang, Yaojun Liu, Xinyue Zhang, et al. "Comparison of Ameliorative Effects between Probiotic and Biodegradable Bacillus subtilis on Zearalenone Toxicosis in Gilts." Toxins 13, no. 12 (2021): 882. http://dx.doi.org/10.3390/toxins13120882.

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This study was conducted to compare the potential ameliorative effects between probiotic Bacillus subtilis and biodegradable Bacillus subtilis on zearalenone (ZEN) toxicosis in gilts. Thirty-six Landrace×Yorkshire gilts (average BW = 64 kg) were randomly divided into four groups: (1) Normal control diet group (NC) fed the basal diet containing few ZEN (17.5 μg/kg); (2) ZEN contaminated group (ZC) fed the contaminated diet containing an exceeded limit dose of ZEN (about 300 μg/kg); (3) Probiotic agent group (PB) fed the ZC diet with added 5 × 109 CFU/kg of probiotic Bacillus subtilis ANSB010; (
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6

Nandi, Suchhanda. "Antibiotic resistance of bacterial Isolates from Food and Environment: In vitro and In silico Analysis." Bioscience Biotechnology Research Communications 17, no. 1 (2024): 25–32. http://dx.doi.org/10.21786/bbrc/17.1.5.

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Manifold types of environmental samples have been known to be contaminated with potential bacterial pathogens stretching the global world with several infections in humans. Among six samples including five environmental samples and one food sample were taken up for in vitro study. Applying the disc diffusion method using 10 antibiotics, the isolated bacterial susceptibility to antibiotics was performed and MAR (multiple antibiotic resistance) index was calculated. All the bacterial isolates were sensitive to AK (amikacin), CIP (ciprofloxacin), VA (vancomycin), TE (tetracycline), MRP (meropenem
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7

Thiruvengadam, Raguchander, Karthikeyan Gandhi, Sendhilvel Vaithiyanathan, et al. "Complete Genome Sequence Analysis of Bacillus subtilis Bbv57, a Promising Biocontrol Agent against Phytopathogens." International Journal of Molecular Sciences 23, no. 17 (2022): 9732. http://dx.doi.org/10.3390/ijms23179732.

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Plant growth-promoting rhizobacteria (PGPR) are a group of root-associated beneficial bacteria emerging as one of the powerful agents in sustainable plant disease management. Among the PGPR, Bacillus sp. has become a popular biocontrol agent for controlling pests and the diseases of several crops of agricultural and horticultural importance. Understanding the molecular basis of the plant growth-promoting and biocontrol abilities of Bacillus spp. will allow us to develop multifunctional microbial consortia for sustainable agriculture. In our study, we attempted to unravel the genome complexity
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8

Yang, Jinpeng, Xinyue Zhang, Ziyao Zhou, et al. "Protective Effects of Bacillus subtilis HH2 against Oral Enterotoxigenic Escherichia coli in Beagles." Veterinary Sciences 10, no. 7 (2023): 432. http://dx.doi.org/10.3390/vetsci10070432.

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This study evaluated the protective effect of Bacillus subtilis HH2 on beagles orally challenged with enterotoxigenic Escherichia coli (ETEC). We assessed the physiological parameters and the severity of diarrhea, as well as the changes in three serum immunoglobulins (IgG, IgA, and IgM), plasma diamine oxidase (DAO), D-lactate (D-LA), and the fecal microbiome. Feeding B. subtilis HH2 significantly reduced the severity of diarrhea after the ETEC challenge (p < 0.05) and increased serum levels of IgG, IgA, and IgM (p < 0.01). B. subtilis HH2 administration also reduced serum levels of DAO
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Syasya Billah, Amanda, Andi Marini Indriani, and Gunaedy Utomo. "PENGARUH BAKTERI BACILLUS SUBTILIS TERHADAP KEKUATAN BATU BATA MENGGUNAKAN LUMPUR LIMBAH IPA." Jurnal Gradasi Teknik Sipil 7, no. 2 (2024): 202–10. http://dx.doi.org/10.31961/gradasi.v7i2.2089.

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Lumpur Limbah IPA mengandung bahan kimia yang dapat menimbulkan pencemaran pada sungai. Untuk mengurangi pencemaran, lumpur limbah IPA dapat dimanfaatkan menjadi bahan pembuatan batu bata. Selain itu pada penelitian ini dalam pembuatan batu bata tidak dibakar agar tidak menimbulkan polusi udara. Batu bata yang dibuat tanpa dibakar umumnya menggunakan semen dalam campuran tanah liat. Semen sendiri dalam proses pembuatannya dapat menimbulkan limbah. Salah satu upaya untuk menghindari pencemaran adalah menggunakan bakteri Bacillus subtilis yang ramah lingkungan untuk meningkatkan kekuatan dari ba
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10

Maheerthanan, RA, M. Ravi, G. Preetha, B. Jeberlin Prabina, and A. Sowmiya. "Impact of Plant Growth-promoting Rhizobacteria on the Incidence of Aphids (Aphis gossypii) in Okra." International Journal of Plant & Soil Science 36, no. 11 (2024): 466–76. http://dx.doi.org/10.9734/ijpss/2024/v36i115163.

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Okra (Abelmoschus esculentus L. Moench) is a widely cultivated vegetable in Asia, facing ongoing challenges from aphids (Aphis gossypii Glover). A field study was conducted on a microplot in Kasilingapuram, Karungulam block, Thoothukudi district, during the Rabi season of 2020 and the Summer of 2021. Various plant growth-promoting rhizobacteria (PGPRs) were applied to the hybrid COBh 4 okra cultivars through soil, seed, and foliar treatments, and their impact on aphid populations was assessed. The findings revealed a significant reduction in aphid numbers and enhanced production of defensive c
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11

Sun, D., and I. Takahashi. "Suppressor mutations for crs mutants of Bacillus subtilis." Canadian Journal of Microbiology 31, no. 5 (1985): 429–35. http://dx.doi.org/10.1139/m85-080.

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Mutants of Bacillus subtilis which carried suppressor mutations for catabolite-resistance gene crsA47 were isolated from methylmethanesulfonate-treated cultures of GLU-47 (crsA47). The suppressor mutation, sca19, suppressed resistance of crsA47 mutant to glucose and other inhibitors of sporulation. Moreover, the suppressor mutation could restore the rate of growth and the level of IMP dehydrogenase and alkaline phosphatase of crsA47 mutant to the wild-type level. The sca19 mutation was also able to suppress catabolite resistance of other crs mutants. The map position of the sea19 mutation indi
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12

Calvio, Cinzia, Francesco Celandroni, Emilia Ghelardi, et al. "Swarming Differentiation and Swimming Motility in Bacillus subtilis Are Controlled by swrA, a Newly Identified Dicistronic Operon." Journal of Bacteriology 187, no. 15 (2005): 5356–66. http://dx.doi.org/10.1128/jb.187.15.5356-5366.2005.

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ABSTRACT The number and disposition of flagella harbored by eubacteria are regulated by a specific trait successfully maintained over generations. The genes governing the number of flagella in Bacillus subtilis have never been identified, although the ifm locus has long been recognized to influence the motility phenotype of this microorganism. The characterization of a spontaneous ifm mutant of B. subtilis, displaying diverse degrees of cell flagellation in both liquid and solid media, raised the question of how the ifm locus governs the number and assembly of functional flagella. The major fi
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13

Senesi, Sonia, Emilia Ghelardi, Francesco Celandroni, Sara Salvetti, Eva Parisio, and Alessandro Galizzi. "Surface-Associated Flagellum Formation and Swarming Differentiation in Bacillus subtilis Are Controlled by the ifm Locus." Journal of Bacteriology 186, no. 4 (2004): 1158–64. http://dx.doi.org/10.1128/jb.186.4.1158-1164.2004.

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ABSTRACT Knowledge of the highly regulated processes governing the production of flagella in Bacillus subtilis is the result of several observations obtained from growing this microorganism in liquid cultures. No information is available regarding the regulation of flagellar formation in B. subtilis in response to contact with a solid surface. One of the best-characterized responses of flagellated eubacteria to surfaces is swarming motility, a coordinate cell differentiation process that allows collective movement of bacteria over solid substrates. This study describes the swarming ability of
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14

Huang, Meixue, Jing Guo, Yanyan Jia, et al. "A Bacillus subtilis Strain ZJ20 with AFB1 Detoxification Ability: A Comprehensive Analysis." Biology 12, no. 9 (2023): 1195. http://dx.doi.org/10.3390/biology12091195.

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As a class I carcinogen, aflatoxin can cause serious damage to various tissues and organs through oxidative stress injuries. The liver, as the target organ of AFB1, is the most seriously damaged. Biological methods are commonly used to degrade AFB1. In our study, the aflatoxin B1-degrading strain ZJ20 was screened from AFB1-contaminated feed and soil, and the degradation of AFB1 by ZJ20 was investigated. The whole genome of strain ZJ20 was analyzed, revealing the genomic complexity of strain ZJ20. The 16S rRNA analysis of strain ZJ20 showed 100% identity to Bacillus subtilis IAM 12118. Through
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15

Misgana, Mitiku. "INTEGRATED MANAGEMENT OF CHOCOLATE SPOT (BOTRYTIS FABAE) DISEASE OF FABA BEAN (VICIA FABA L.) IN ETHIOPIA: A REVIEW." International Journal of Research - Granthaalayah 5, no. 9 (2017): 195–205. https://doi.org/10.5281/zenodo.1002638.

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The primary producers of pulses are small-scale farmers with small and dispersed plots under rain-fed conditions with substantially lower yields of less than 0.9 t/ha as compared to the improved faba bean varieties and international yields. There are many biotic and abiotic factors which hampers faba bean production in Ethiopia. From biotic factors chocolate spot (Botrytis fabae Sard.) is the major fungal disease hampering faba bean production in Ethiopia.). It is a highly prevalent and destructive disease, causing yield loss up to 61% on a susceptible and 34% on tolerant faba bean genotypes i
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16

Mondal, Prasenjit, та Sumanta Mondal. "Synthesis, characterization and SAR studies of Novel Series of Spiro β-Lactam of 5-methyl-indole-2,3-dione derivatives as a potential antibacterial and anthelmintic agent". Current Chemistry Letters 11, № 4 (2022): 403–14. http://dx.doi.org/10.5267/j.ccl.2022.5.001.

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A novel series of spiro cyclo-indolyl β-lactam compounds of the 5-methyl-indole-2,3-dione derivatives has been synthesized from the new Schiff bases Isatin, using the Staudinger synthesis. FT-IR, 1H-NMR, 13C-NMR, mass spectroscopy, and elemental analyses were used to describe the produced chemicals. The anthelmintic potency of the produced compounds was evaluated using standard albendazole. The antibacterial activity also tested for the synthesized compounds by calculating the zone of inhibition using cup plate method and by comparison with the standard Ampicillin against the five different pa
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17

Abdel-Kader, M. M., M. S. A. Khalil, and N. S. El-Mougy. "Efficacy of fungicide alternatives against late wilt disease of maize and their influence on plant morphogenesis and yield characters." Hellenic Plant Protection Journal 15, no. 2 (2022): 57–71. http://dx.doi.org/10.2478/hppj-2022-0007.

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Summary Efficiency of various organic acids, organic salts, essential oils, algae (an extract of Chlorella vulgaris and a commercial product), and bioagents against Magnaporthiopsis maydis, causing maize late wilt disease, was evaluated in laboratory and field conditions. For the in vitro tests, isolated M. maydis field strains from Egypt were used. Additionally, in field experiments different application methods were tested for their efficacy throughout two successive growing seasons. Results showed maximum growth inhibition of M. maydis at different concentrations of salicylic acid, ascorbic
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18

Petrov, Sergei A., Vladimir A. Malchevski, Andrei M. Subbotin, Alexandr S. Bazhin, and Maxim V. Naruchko. "ULTRASTRUCTURAL ORGANIZATION OF THE BACILLUS SUBTILIS BIOFILM MATRIX IN THE STATIONARY PHASE." Siberian Journal of Life Sciences and Agriculture 16, no. 6 (2024): 179–201. https://doi.org/10.12731/2658-6649-2024-16-6-994.

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Background. The ecological and geographical conditions of microorganisms (MO) can influence the ultrastructural organisation of their biofilm matrix and the accumulation of various bioactive compounds in it. Knowledge of such organisation in Arctic paleobacteria is extremely important for studying the mechanisms of biosynthesis and dispersion of biofilms formed by them, based on complex genetic programmes. Purpose. Demonstrate the possibilities and show the main technical achievements of electron microscopy in the field of studying the biofilm matrix of palaeobacterium Bacillus sp. strain B1M
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MITSUBOSHI, SAORI, RIE OBITSU, KANAKO MURAMATSU, KENTARO FURUBE, SHIGEHIRO YOSHITAKE, and KAN KIUCHI. "Growth Inhibitory Effect of Shelf Life Extending Agents on Bacillus subtilis IAM 1026." Biocontrol Science 12, no. 2 (2007): 71–75. http://dx.doi.org/10.4265/bio.12.71.

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20

Mali, Suraj N., Amit Anand, Magdi E. A. Zaki, et al. "Theoretical and Anti-Klebsiella pneumoniae Evaluations of Substituted 2,7-dimethylimidazo[1,2-a]pyridine-3-carboxamide and Imidazopyridine Hydrazide Derivatives." Molecules 28, no. 6 (2023): 2801. http://dx.doi.org/10.3390/molecules28062801.

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A series of multistep synthesis protocols was adopted to synthesize substituted imidazopyridines (IMPs) (SM-IMP-01 to SM-IMP-13, and DA-01-05). All substituted IMPs were then characterized using standard spectroscopic techniques such as 1H-NMR, 13C-NMR, elemental analyses, and mass spectrometry. Our both in vitro qualitative and quantitative results for antibacterial analysis, against Klebsiella pneumoniae ATCC 4352 and Bacillus subtilis ATCC 6051 suggested that all compounds essentially exhibited activity against selected strains of bacteria. Our DFT analyses suggested that the compounds of t
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Jung, Ariee, Julie A. Swartzendruber, Ryan Incrocci, and Rosalind Del Toro. "Impact of oral probiotic treatment in murine model of atopic dermatitis." Journal of Immunology 206, no. 1_Supplement (2021): 94.19. http://dx.doi.org/10.4049/jimmunol.206.supp.94.19.

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Abstract The number of people with allergies has been on the rise over the last half-century; and the most common allergen afflicting humans, dogs and cats is the house dust mite (HDM). The rise in allergic disease correlates with an increasingly sterile living environment and reduced exposure to bacteria. We predict that exposure to non-pathogenic bacteria helps educate our immune system to become tolerant to innocuous material, such as allergens. Our previous studies have found that Bacillus subtilis, a gram-positive spore forming bacterium, can reduce the symptoms of HDM-induced allergic lu
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Ashurbekova, Tamila, Patimat Omarova, Elmira Musinova, Denis Efimov, Viktor Onkaev, and Olga Krotova. "The expediency of using an integrated plant protection system and organomineral fertilizers in the conditions of the Southern natural and economic zone." BIO Web of Conferences 113 (2024): 01017. http://dx.doi.org/10.1051/bioconf/202411301017.

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The authors of the article conducted research and comparative analysis of the impact of the branch's products FGBI "Rosselkhoznadzor" in the Rostov region fertilizers Vostok EM–1, containing live cultures of effective microorganisms (photosynthetic and lactic acid bacteria, yeast, actinomycetes, fermenting fungi); organo-mineral fertilizer based on humic acids Humate +7 grade C2 liquid concentrate, organo-mineral fertilizer based on humic acids Green-Organic Gum–1; o study the effect of the microbiological fungicide Metabacterin produced by Inagro LLC, a joint venture based on live cultures of
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23

Ramos Pupo, Raul, Laura M. Reyes Diaz, Gisela M. Suarez Formigo, et al. "Mucosal Vaccination Against SARS-CoV-2 Using Human Probiotic Bacillus subtilis Spores as an Adjuvant Induces Potent Systemic and Mucosal Immunity." Vaccines 13, no. 7 (2025): 772. https://doi.org/10.3390/vaccines13070772.

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Background/Objectives: The ongoing evolution of SARS-CoV-2 has highlighted the limitations of parenteral vaccines in preventing viral transmission, largely due to their failure to elicit robust mucosal immunity. Methods: Here, we evaluated an intranasal (IN) vaccine formulation consisting of recombinant receptor-binding domain (RBD) adsorbed onto human probiotic Bacillus subtilis DG101 spores. Results: In BALB/c mice, IN spore-RBD immunization induced strong systemic and mucosal humoral responses, including elevated specific IgG, IgM, and IgA levels in serum, bronchoalveolar lavage fluid (BALF
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Tayyab, Muhammad, Waqar Islam, Waqas Waqas, and Yueling Zhang. "Probiotic–Vaccine Synergy in Fish Aquaculture: Exploring Microbiome-Immune Interactions for Enhanced Vaccine Efficacy." Biology 14, no. 6 (2025): 629. https://doi.org/10.3390/biology14060629.

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The rapid expansion of aquaculture is vital for global food security, yet it faces persistent threats from disease outbreaks, vaccine inefficacy, and antibiotic overuse, all of which undermine sustainability. Conventional vaccines often fail to induce robust mucosal immunity, spurring interest in probiotics as adjuvants to enhance immunogenicity. Probiotics such as Bacillus subtilis and Lactobacillus casei modulate fish microbiomes, fortify mucosal barriers, and activate innate immune responses via mechanisms including Toll-like receptor signaling and cytokine production. These actions prime t
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Spiehs, Mindy, Gerald Shurson, and Lee Johnston. "Effects of two direct-fed microbials on the ability of pigs to resist an infection with Salmonella enterica serovar Typhimurium." Journal of Swine Health and Production 16, no. 1 (2008): 27–36. http://dx.doi.org/10.54846/jshap/534.

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Objective: To evaluate the effects of direct-fed microbials (DFMs) containing either Bacillus licheniformis and Bacillus subtilis or Enterococcus faecium on the ability of finisher pigs to resist a Salmonella serovar Typhimurium infection. Materials and methods: Forty finishing pigs were used in a 12-day disease challenge study. Dietary treatments included no DFM (Control; 20 pigs), DFM provided in drinking water (E faecium), or DFM provided in feed (Bacillus). Ten Control pigs were not challenged with Salmonella Typhimurium; the remaining 30 pigs were inoculated on Day 0. Fecal samples were c
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Dong, Xiaoli, Naifeng Zhang, Meng Zhou, Yan Tu, Kaidong Deng, and Qiyu Diao. "Effects of dietary probiotics on growth performance, faecal microbiota and serum profiles in weaned piglets." Animal Production Science 54, no. 5 (2014): 616. http://dx.doi.org/10.1071/an12372.

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This study was conducted to evaluate the effects of dietary supplementation with probiotics on growth performance, faecal microbiota, and serum profiles in weaned piglets. Large White × Landrace piglets (n = 144) weaned at 35–37 days of age were selected and divided into four groups, and the piglets from each group were assigned randomly to six pens (replicates) with six animals each. Each group was fed one of four diets for 5 weeks: a basal diet without antibiotics and probiotics (control), or the basal diet supplemented with Lactobacillus plantarum GF103, Bacillus subtilis B27, or a mixture
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Miyagawa, Ken-ichiro, Hiroyuki Kimura, Kazuo Nakahama, et al. "Cloning of the Bacillus Subtilis IMP Dehydrogenase Gene and its Application to Increased Production of Guanosine." Nature Biotechnology 4, no. 3 (1986): 225–28. http://dx.doi.org/10.1038/nbt0386-225.

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Dwisandi, Reza Fauzi, Frista Mutiara, Elsa Nurfauziah, and Vita Meylani. "effectiveness of indigenous local microorganisms in degrading hexavalent chromium (Cr(VI)) in Batik liquid waste." Biological Environment and Pollution 1, no. 1 (2021): 19–29. http://dx.doi.org/10.31763/bioenvipo.v1i1.383.

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The batik industry in Indonesia has an IKM (Small and Medium Industry) scale so that it does not yet have adequate waste treatment. In the long term, waste is disposed of directly into the environment which can damage aquatic ecosystems and harm human health. Textile wastewater has a complementary picture and has a deep color. One of the most dangerous heavy metals contained in textile waste is hexavalent chromium (Cr(VI)). Several ways can be done to reduce hexavalent chromium (Cr(VI)) by bioremediation. Based on the results of the literature review, it shows that the bioremediation agents fr
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29

Jobe, Dean A., Nenoo Rawal, Ronald F. Schell, and Steven M. Callister. "Detection of Borreliacidal Antibodies in Lyme Borreliosis Patient Sera Containing Antimicrobial Agents." Clinical Diagnostic Laboratory Immunology 6, no. 6 (1999): 930–33. http://dx.doi.org/10.1128/cdli.6.6.930-933.1999.

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ABSTRACT The borreliacidal-antibody test has been used for the serological detection and confirmation of Lyme borreliosis. However, the presence of antimicrobial agents in serum can confound the accurate detection of borreliacidal antibodies. In this study, we developed a Bacillus subtilis agar diffusion bioassay to detect small concentrations of antimicrobial agents in serum. We also used XAD-16, a nonionic polymeric resin, to adsorb and remove high concentrations of amoxicillin, cefotaxime, ceftriaxone, cefuroxime, doxycycline, and erythromycin without significantly affecting even small conc
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Liu, Kaifang, Shubin Liu, Dexiang Feng, et al. "Fermentation Products Originated from Bacillus subtilis Promote Hepatic–Intestinal Health in Largemouth Bass, Micropterus salmoides." Biology 14, no. 6 (2025): 646. https://doi.org/10.3390/biology14060646.

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The fermentation product FP-WeiGuangSu is regarded as a novel, green and efficient antibiotic substitute. Such products constitute one of the principal strategies for addressing bacterial diseases in aquaculture in the future. This study investigates the effects of FPs derived from Bacillus subtilis on the antioxidant capacity and gut microbiota of Largemouth Bass (Micropterus salmoides). Experimental diets containing 0, 1%, 3% and 5% FPs (Control, H1, H2 and H3) were fed to M. salmoides. Although short-term administration of FPs exerted no significant influence on the growth performance of La
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Gao, Yang, Xingchen Huo, Zhensheng Wang, et al. "Oral Administration of Bacillus subtilis Subunit Vaccine Significantly Enhances the Immune Protection of Grass Carp against GCRV-II Infection." Viruses 14, no. 1 (2021): 30. http://dx.doi.org/10.3390/v14010030.

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Grass carp reovirus (GCRV) is a severe virus that causes great losses to grass carp culture every year, and GCRV-II is the current popular and fatal strain. VP56, fibrin on the outer surface of GCRV-II, mediates cell attachment. In this study, we firstly divided the VP56 gene into four fragments to screen the optimal antigen by enzyme-linked immunosorbent assay and neutralizing antibody methods. The second fragment VP56-2 demonstrates the optimal efficiency and was employed as an antigen in the following experiments. Bacillus subtilis were used as a carrier, and VP56-2 was expressed on the sur
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Xu, Qian, Zheng Yang, Siyu Chen, et al. "Effects of Replacing Dietary Fish Meal by Soybean Meal Co-Fermented Using Bacillus subtilis and Enterococcus faecium on Serum Antioxidant Indices and Gut Microbiota of Crucian Carp Carassius auratus." Fishes 7, no. 2 (2022): 54. http://dx.doi.org/10.3390/fishes7020054.

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Fermented soybean meal (FSM) is an important feed material that can replace fish meal to solve the shortage of animal protein. To improve the utilization of FSM, we optimized the co-fermentation conditions of soybean meal using Bacillus subtilis and Enterococcus faecium and studied the effects of replacing fish meal with different proportions of FSM on serum antioxidant indices and gut microbiota (GM) composition of crucian carp (Carassius auratus). Our results showed that the co-fermentation of soybean meal was the most effective when the ratio of B. subtilis X-2 and E. faecium X-4 was 2:3, g
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Vicente-Gil, Samuel, Rocío Simón, Silvia Nogales-Mérida, et al. "Bacillus subtilis supplemented feeding as a method to increase IgM titers and affinity in response to fish vaccination." Fish & Shellfish Immunology 162 (July 2025): 110335. https://doi.org/10.1016/j.fsi.2025.110335.

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Guimarães, Mateus Cardoso, Isabel M. Cerezo, Miguel Frederico Fernandez-Alarcon, et al. "Oral Administration of Probiotics (Bacillus subtilis and Lactobacillus plantarum) in Nile Tilapia (Oreochromis niloticus) Vaccinated and Challenged with Streptococcus agalactiae." Fishes 7, no. 4 (2022): 211. http://dx.doi.org/10.3390/fishes7040211.

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Streptococcus agalactiae is an important bacterial pathogen in intensive Nile tilapia production, causing high mortality rates and great economic losses. This work aimed to evaluate the Nile tilapia vaccination against S. agalactiae and fed with ration containing probiotic AQUA PHOTO® composed of Bacillus subtilis and Lactobacillus plantarum, on the immune response action and gut microbiota. The experimental design was completely randomized with five treatments (CON = control; ADJ = adjuvant; PRO = probiotic; VAC = vaccine; PRO + VAC = probiotic + vaccine) and five replicates. The vaccine (bac
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35

Mitiku, Misgana. "INTEGRATED MANAGEMENT OF CHOCOLATE SPOT (BOTRYTIS FABAE) DISEASE OF FABA BEAN (VICIA FABA L.) IN ETHIOPIA: A REVIEW." International Journal of Research -GRANTHAALAYAH 5, no. 9 (2017): 195–205. http://dx.doi.org/10.29121/granthaalayah.v5.i9.2017.2231.

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The primary producers of pulses are small-scale farmers with small and dispersed plots under rain-fed conditions with substantially lower yields of less than 0.9 t/ha as compared to the improved faba bean varieties and international yields. There are many biotic and abiotic factors which hampers faba bean production in Ethiopia. From biotic factors chocolate spot (Botrytis fabae Sard.) is the major fungal disease hampering faba bean production in Ethiopia.). It is a highly prevalent and destructive disease, causing yield loss up to 61% on a susceptible and 34% on tolerant faba bean genotypes i
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Miyagawa, Ken-ichiro, Naoyuki Kanzaki, Hiroyuki Kimura, Yasuhiro Sumino, Shun-ichi Akiyama, and Yoshio Nakao. "Increased Inosine Production by a Bacillus subtilis Xanthine-Requiring Mutant Derived by Insertional Inactivation of the IMP Dehydrogenase Gene." Nature Biotechnology 7, no. 8 (1989): 821–24. http://dx.doi.org/10.1038/nbt0889-821.

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37

Mäntsälä, P., and H. Zalkin. "Cloning and sequence of Bacillus subtilis purA and guaA, involved in the conversion of IMP to AMP and GMP." Journal of Bacteriology 174, no. 6 (1992): 1883–90. http://dx.doi.org/10.1128/jb.174.6.1883-1890.1992.

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38

Panichayupakaranant, Pharkphoom. "α-Mangostin-Rich Extract: A Potential Oral Antibacterial Agent Prepared by Green Extraction". International Journal of Pharmacognosy & Chinese Medicine 4, № 2 (2020): 1–6. http://dx.doi.org/10.23880/ipcm-16000201.

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The purpose of this study was to prepare α-mangostin-rich extract (AME) using a green microwave extraction together with a simple one-step green fractionation method on a hydrophobic resin column. Based on the established method, AME containing 95% w/w α-mangostin content was obtained with an extract yield of 0.46% w/w dry plant powder. In addition, investigation of its antibacterial activity against oral pathogenic bacteria, including Streptococcus mitis, S. mutans, S. pyogenes and Bacillus subtilis, compared with the standard marker, α-mangostin found that AME exhibited strong antibacterial
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Serebryanaya, Fatima. "Pharmacotechnological Investigations of the Hedysarum caucasicum from the Northern Caucasus." International Journal of Pharmacognosy & Chinese Medicine 5, no. 2 (2021): 1–10. http://dx.doi.org/10.23880/ipcm-16000221.

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The main active component of species of the genus Hedysarum are xanthones, the main of them is C-glycoside-mangiferin, which was found in the aerial part of 17 species of Hedysarum. Mangiferin is contained in plants of the genus Hedysarum can serve as a chemotaxonomic marker of this section, it has antiviral activity against DNA-containing viruses: Herpes simplex virus, Varicella zoster, Cytomegalovirus, also has immunostimulatory properties (stimulates cellular and humoral immunity). We have prepared the phytochemical investigations of xanthones. The quantitative maintenance of the sum of xan
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Singh, M. P., P. J. Petersen, W. J. Weiss, F. Kong, and M. Greenstein. "Saccharomicins, Novel Heptadecaglycoside Antibiotics Produced by Saccharothrix espanaensis: Antibacterial and Mechanistic Activities." Antimicrobial Agents and Chemotherapy 44, no. 8 (2000): 2154–59. http://dx.doi.org/10.1128/aac.44.8.2154-2159.2000.

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ABSTRACT Saccharomicins A and B, two new heptadecaglycoside antibiotics, were isolated from the fermentation broth of the rare actinomyceteSaccharothrix espanaensis. They represent a novel class of bactericidal antibiotics that are active both in vitro and in vivo against bacteria and yeast (MICs: Staphylococcus aureus, <0.12 to 0.5; vancomycin-resistant enterococci, 0.25 to 16; gram-negative bacteria, 0.25 to >128; and yeast, >128 μg/ml), including multiply resistant strains. Saccharomicins protected mice from lethal challenges by staphylococci (subcutaneous 50% effective dose range
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Su, Xiangtan, Ke Wang, Yeqing Liu, et al. "Single or Combined Supplementation of Rhodotorula Yeast Culture and Bacillus Subtilis Enhances Intestinal Barrier Function in Yellow-Feathered Broilers." Veterinary Sciences 12, no. 6 (2025): 558. https://doi.org/10.3390/vetsci12060558.

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This study aimed to investigate the effects of dietary supplementation with Rhodotorula yeast cultures (RYC) and Bacillus subtilis (BS), alone or in combination, on growth performance and intestinal barrier function in yellow-feathered broilers. A 2 × 2 factorial interaction study was conducted, in which a total of 192 one-day-old yellow-feathered broilers were randomly assigned into four treatment groups: CON group, fed a basal diet; BS group, supplemented with 5 × 109 CFU/kg of BS; RYC group, supplemented with 5000 mg/kg of RYC; and RYC + BS group, supplemented with both. During the 56-day e
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G, Adaikala Raj. "Assessment of Antibacterial Activity of Various Solvent Extracts of Dictyota Dichotoma Against Multidrug Resistant Bacterial Strain." International Journal of Pharmacognosy & Chinese Medicine 8, no. 2 (2024): 1–8. http://dx.doi.org/10.23880/ipcm-16000279.

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In this research, investigate the antibacterial properties of various crude extracts obtained from the brown alga Dictyota dichotoma (Hudson) J.V.Lamouroux. Specifically, we analyzed the hexane, chloroform, ethyl acetate, and methanol extracts in detail to assess their effectiveness against a wide range of multidrug-resistant bacterial strains. These strains encompassed Staphylococcus aureus, Bacillus subtilis, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhimurium, Vibrio cholerae, Shigella flexneri, Proteus mirabilis, and P. vulgaris,
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Safari, Hassan, Ardeshir Mohit, and Maziar Mohiti-Asli. "Improving the Antioxidant Status, Meat Quality, and Immune Response of Broilers by Fermented Feather Meal." Iranian Journal of Veterinary Medicine 19, no. 02 (2025): 279–98. https://doi.org/10.32598/ijvm.19.2.1005483.

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Background: Feather biodegradation is an effective alternative to other processing methods. Objectives: This study aims to investigate the effects of hydrolyzed feather meal (HFM) on broilers’ antioxidant status, meat quality, and immune response. Methods: In October 2022, 480-day-old Ross 308 male broilers were used for 42 days in a completely randomized design with eight treatments and five replicates (12 chicks/replicate) in the research farm of Agriculture Faculty, Guilan University (Rasht City, Iran). The experimental diets were as follows: (1) control diet (without feather meal [FM]), (2
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Zhu, Hong-hui, Jun Guo, Qing Yao, et al. "Streptomyces vietnamensis sp. nov., a streptomycete with violet–blue diffusible pigment isolated from soil in Vietnam." International Journal of Systematic and Evolutionary Microbiology 57, no. 8 (2007): 1770–74. http://dx.doi.org/10.1099/ijs.0.64774-0.

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An actinomycete, designated strain GIMV4.0001T, was isolated from a forest soil sample in Vietnam. It produced white aerial mycelium and violet–blue diffusible pigment on Gause's synthetic agar. The substrate mycelium colour was not sensitive to pH. Micoscopic observations revealed that strain GIMV4.0001T produced long, straight chains of cylindrical spores, and chemotaxonomic data confirmed that it belongs to the genus Streptomyces. Melanin was produced, but no antibacterial activity was evident against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, Candida albicans or Penicilli
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Czech, A., I. Sembratowicz, and G. Zieba. "Effect of the use of Yarrowia lipolytica and Saccharomyces cerevisiae yeast with a probiotic in the diet of turkeys on their gut microbiota and immunity." Veterinární Medicína 65, No. 4 (2020): 174–82. http://dx.doi.org/10.17221/145/2019-vetmed.

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An experiment was carried out to determine whether the yeast species Yarrowia lipolytica added to compound feeds for turkeys would have a more beneficial effect on their immunity and gut microflora composition than the commonly used species Saccharomyces cerevisiae. An additional aim of the study was to test whether the addition of a probiotic (Bacillus licheniformis and Bacillus subtilis) to the feed containing Yarrowia lipolytica or Saccharomyces cerevisiae yeast would enhance their effect. The experiment was carried out on growing turkey hens aged 7 to 112 days and randomly divided into six
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Ostapchenko, Danylo, Olexandr Korotkyi, Yu Penchyk, Olena Tsyryuk, and Liubov Sichel. "ANTIMICROBIAL POTENTIAL OF LACTIC ACID BACTERIA LACTOBACILLUS RHAMNOSUS LYSATE." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology 91, no. 4 (2022): 19–23. http://dx.doi.org/10.17721/1728.2748.2022.91.19-23.

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According to World Health Organization, antibiotic resistance is rising to dangerously high levels in all parts of the world. New resistance mechanisms are emerging and spreading globally, threatening our ability to treat common infectious diseases. Therefore, searching for new antimicrobial agents of natural origin is an extraordinary global problem. The work aimed to determine the antimicrobial activity of lyophilized enzymatic lysate of cells of the Lactobacillus rhamnosus V strain of lactic acid bacteria. The object of the study was the drug Del-Imun V®, which hasanti-allergican dimmuno st
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Dong, Bowen, Lu Shen, Mei Yang, Kaitai Yang, and Fei Cheng. "Structure and Bioactivity of Intracellular and Extracellular Polysaccharides of Trametes lactinea Mycelium." Microorganisms 12, no. 7 (2024): 1431. http://dx.doi.org/10.3390/microorganisms12071431.

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Trametes lactinea polysaccharides have a high medicinal value; however, we still know little about the structure and bioactivity of intracellular and extracellular polysaccharides in the mycelial liquid fermentation of T. lactinea. This study analyzed the structures of intracellular (IP-1, IP-2, and IP-3) and extracellular (EP-1 and EP-2) polysaccharide components isolated from T. lactinea liquid fermentation, as well as investigated their antioxidant, antibacterial, and immunomodulatory properties. The results showed that IP-3 was the only component with a triple-helix structure, while the ot
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48

Singh, M. P., P. J. Petersen, W. J. Weiss, et al. "Mannopeptimycins, New Cyclic Glycopeptide Antibiotics Produced by Streptomyces hygroscopicus LL-AC98: Antibacterial and Mechanistic Activities." Antimicrobial Agents and Chemotherapy 47, no. 1 (2003): 62–69. http://dx.doi.org/10.1128/aac.47.1.62-69.2003.

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ABSTRACT Mannopeptimycins α, β, γ, δ, and ε are new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98. Mannopeptimycins γ, δ, and ε, which have an isovaleryl substitution at various positions on the terminal mannose of the disaccharide moiety, demonstrated moderate to good antibacterial activities. Mannopeptimycin ε was the most active component against methicillin-resistant staphylococci and vancomycin-resistant enterococci (MICs, 2 to 4 μg/ml for staphylococci and streptococci and 4 to 32 μg/ml for enterococci), while mannopeptimycins γ and δ were two- to fourfol
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Amuguni, Hellen, and Saul Tzipori. "Bacillus subtilis." Human Vaccines & Immunotherapeutics 8, no. 7 (2012): 979–86. http://dx.doi.org/10.4161/hv.20694.

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Kovács, Ákos T. "Bacillus subtilis." Trends in Microbiology 27, no. 8 (2019): 724–25. http://dx.doi.org/10.1016/j.tim.2019.03.008.

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