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1
Meuzelaar, Henk L. C. "Editorial: Back to the future." Field Analytical Chemistry & Technology 1, no. 1 (1996): 1. http://dx.doi.org/10.1002/(sici)1520-6521(1996)1:1<1::aid-fact1>3.0.co;2-3.
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Millard, J., J. Havlíček, I. Tichá, and J. Hron. "Strategies for the future eGovernment." Agricultural Economics (Zemědělská ekonomika) 50, No. 1 (February 24, 2012): 20–28. http://dx.doi.org/10.17221/5162-agricecon.
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The paper provides some of the interim results of the Fifth Framework PRISMA project dealing with the of impact ICT on government and citizen services in Europe. The analysis and the concept description of long-term strategies for eGovernment and a long-term vision over 10 years for eGovernment are described. Activities performed by the government are analysed from the demand (“front office”) and supply (“back office”) point of view. Recommendations for long-term strategic decisions are based on three scenarios of the future European development till 2010: (1) “Prosperous and just Europe”, (2) “Turbulent world”, (3) “Recession and reorientation”.
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Shcherbakova, Natalia, and Shane Desselle. "Looking Back at US Pharmacy’s Past to Help Discern Its Future." Annals of Pharmacotherapy 54, no. 9 (March 1, 2020): 907–20. http://dx.doi.org/10.1177/1060028020911085.
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Objective: To review specific literature that aimed to predict the future of US pharmacy, beginning in the late 1980s. Data Sources: Articles were identified from searching MEDLINE, CINAHL, Google Scholar, and references of relevant articles. The following combinations of search terms were used: future, pharmacy, prediction, and forecast. Study Selection and Data Extraction: The following inclusion criteria were applied: (1) full-text commentary, review, or original research and (2) focused predominantly on the pharmacy in the United States. Data on predictions for the future of pharmacy were extracted. Data Synthesis: We selected 3 articles published between 1988 and 2006, with each aiming to project the future for the following decade. We examined each prediction in light of the current knowledge. Relevance to Patient Care and Clinical Practice: Educators, practitioners, and other stakeholders should consider reflecting on the changes in pharmacy for the past 3 decades and applying both historical and emerging trends to improve patient care and sustain practice in the third decade of the 21st century and beyond. Conclusion: Most of the predictions for the future of pharmacy from the past 3 decades materialized, with some still in progress (reimbursement for pharmacy services), whereas others manifested in unexpected ways (transition from shortage to excess of pharmacists). Current forces shaping pharmacy include, but are not limited to, growing spending and use of specialty drugs, automation of pharmacy operations, growth of pharmacy in the digital health enterprise, and growing consumer interest in the use of analytical pharmacy that tests drugs before dispensing.
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Bell, Wendell. "The Sociology of the Future and the Future of Sociology." Sociological Perspectives 39, no. 1 (March 1996): 39–57. http://dx.doi.org/10.2307/1389342.
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Drawing on futures studies for possible future directions of Sociology, I make eight proposals designed to enhance Sociology as an action and policy science: (1) Replace postmodern beliefs with critical realism as a theory of knowledge, thereby avoiding the self-defeating consequences of extreme subjectivism and relativism. (2) Since sound decision making invites knowing the probable future consequences of contemplated actions, give more attention to prediction and the study of self-altering prophecies. (3) Bring moral discourse back into Sociology— explicitly, rigorously, critically, and objectively—focusing on achieving freedom and well-being for human beings. Think (4) globally and (5) holistically, even when working locally. (6) Take the meaning of time seriously and explore the real, though sometimes hidden, alternative present possibilities for the not-yet-evidential future. (7) View people as active agents who strive to create the futures that they want. And (8) in defining society, emphasize expectation, choice, and decision as people, through historical actions, construct society by attempting to transform their images of desirable futures into social realities.
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Danson, Mike. "Back to the Future? Enterprise Zones Mark 2 or 3? Lessons from the 1980's-90's and from Scotland." Regions Magazine 291, no. 1 (August 6, 2013): 16–18. http://dx.doi.org/10.1080/13673882.2013.10739978.
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Karpen, Ingo, and Carolin Plewa. "From Muso to Academic and Back: A Time and Person-Based Acknowledgement of Michael Kleinaltenkamp." Journal of Service Management Research 4, no. 2-3 (2020): 75–83. http://dx.doi.org/10.15358/2511-8676-2020-2-3-75.
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The year 2020 sees an important milestone for Professor Michael Kleinaltenkamp (Michael hereafter), as he concludes his official academic working life. This paper acknowledges the significant contribution Michael has made over the years. In particular, using Leximancer to undertake textmining of Michael’s English language publications, we not only uncover the underlying structure of these contributions but also explore if and how focal themes of his research have changed, particularly considering his close engagement with the Australasian academic marketing community. Findings indicate foundational facets and the overall gestalt of his research over time, yet also point to important differences across the time periods analysed. Finally, we reflect on our findings from a musical perspective, drawing on Michael’s passion for music, as we thank him for the many jams and the rehearsing, aswell as for his support for the bands and scenes he belongs to. For future research, it should be noted that future acknowledgements would benefit from cooking as a metaphor to complete the picture.
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Beutler, Larry E. "“Back to the future” in clinical psychology: Introduction to the first millennial issue." Journal of Clinical Psychology 56, no. 3 (March 2000): 253–55. http://dx.doi.org/10.1002/(sici)1097-4679(200003)56:3<253::aid-jclp1>3.0.co;2-h.
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Cerchione, Roberto, Piera Centobelli, Pierluigi Zerbino, and Amitabh Anand. "Back to the future of Knowledge Management Systems off the beaten paths." Management Decision 58, no. 9 (September 14, 2020): 1953–84. http://dx.doi.org/10.1108/md-11-2019-1601.
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PurposeThe evolution of Knowledge-Management (KM)-related literature has highlighted that Knowledge Management Systems (KMSs) have undergone massive changes in collaborative environments. Information-Systems-enabled KM seems to be the necessary response to the recent challenges posed by globalisation and technology dynamics to both large companies (LCs) and small and medium enterprises (SMEs).Design/methodology/approachThis paper provides a systematic review about KMSs to offer an analytical overview of their role in supporting innovative forms of knowledge translation occurring in collaborative relationships. A sample of 129 papers was selected and analysed according to three perspectives: unit of analysis (LCs, SMEs), phases of the KM process (adoption, translation) and topic area (KM Practices, KM Tools, KMSs).FindingsThe findings highlight five literature gaps: (1) the role of KM practices supporting knowledge translation; (2) the impact of the alignment among KM practices, firm's complexity, dimension and culture on KM process; (3) the effect of KM tools on knowledge translation; (4) the variety of KMSs exploited in both LCs and SMEs; and (5) the alignment between organisational structure and information systems in KM context. Accordingly, 13 research questions were formulated.Originality/valueThe proposed research questions define a formal research agenda that could steer further research efforts about the KMS topic for improving the body of knowledge in the KM field. Scientific literature is currently lacking a contribution assessing the role of KMSs in supporting innovative forms of knowledge translation that occur in collaborative relationships.
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Coleman, Major G. "Reading and Leading: Interviews With RBPE Editors About the Past and the Future of the Review." Review of Black Political Economy 47, no. 2 (June 2020): 125–33. http://dx.doi.org/10.1177/0034644620926515.
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The Review of Black Political Economy has been a leader on issues of race and economics, politics, sociology and area studies. After half a century of shaping minds, critical ideas and arguments, the time has come to look back and ask the editors of the Review what they saw when they were at the helm, and what they see ahead. While all their views are different, common themes emerged: 1. The need to embrace new technologies, 2. Making the Review the first pick for top scholars, 3. Relevancy in the post-civil rights era, and 4. Finance for the 21st century.
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Drucker, A. G., S. J. Hiemstra, N. Louwaars, J. K. Oldenbroek, M. W. Tvedt, I. Hoffmann, K. Awgichew, S. Abegaz Kehedé, P. N. Bhat, and A. da Silva Manante. "Back to the future. How scenarios of future globalisation, biotechnology, disease and climate change can inform present animal genetic resources policy development." Animal Genetic Resources Information 41 (April 2007): 75–89. http://dx.doi.org/10.1017/s1014233900002352.
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SummaryWith the aim of assessing how exchange practices regarding Animal Genetic Resources for Food and Agriculture (AnGR) affect the various stakeholders in the livestock sector and to identify policies and regulatory options that could guide the global exchange, use and conservation of AnGR, an exploration of future scenarios was used as a complementary approach to reviewing the current situation, as well as to identify stakeholders’ views on AnGR policy development.Four 2050 future scenarios were developed and included:1. Globalization and regionalization.2. Biotechnology development.3. Climate change and environmental degradation.4. Diseases and disasters.Having developed the scenarios, these were then used as an input point for a wide range of stakeholder consultations.The findings show that such an approach has been a useful analytical tool. The ‘far’ future perspective appeared to make people less defensive, especially in a situation where current exchange problems were not yet particularly visible or well documented. Many interviewees broadly considered that it was not a question of ‘if’ the scenarios would happen, but rather a question of ‘when’. This implies that we might do well to consider the need to respond to future challenges through the proactive development of new policies or regulations. Such a finding is partly in contrast with the general perception of the current regulatory situation being broadly acceptable.
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Smith, Jo Armour, Andrew Hawkins, Marybeth Grant-Beuttler, Richard Beuttler, and Szu-Ping Lee. "Risk Factors Associated With Low Back Pain in Golfers: A Systematic Review and Meta-analysis." Sports Health: A Multidisciplinary Approach 10, no. 6 (August 21, 2018): 538–46. http://dx.doi.org/10.1177/1941738118795425.
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Context: Low back pain is common in golfers. The risk factors for golf-related low back pain are unclear but may include individual demographic, anthropometric, and practice factors as well as movement characteristics of the golf swing. Objective: The aims of this systematic review were to summarize and synthesize evidence for factors associated with low back pain in recreational and professional golfers. Data Sources: A systematic literature search was conducted using the PubMed, CINAHL, and SPORTDiscus electronic databases through September 2017. Study Selection: Studies were included if they quantified demographic, anthropometric, biomechanical, or practice variables in individuals with and without golf-related low back pain. Study Design: Systematic review and meta-analysis. Level of Evidence: Level 3. Data Extraction: Studies were independently reviewed for inclusion by 2 authors, and the following data were extracted: characterization of low back pain, participant demographics, anthropometrics, biomechanics, strength/flexibility, and practice characteristics. The methodological quality of studies was appraised by 3 authors using a previously published checklist. Where possible, individual and pooled effect sizes of select variables of interest were calculated for differences between golfers with and without pain. Results: The search retrieved 73 articles, 19 of which met the inclusion criteria (12 case-control studies, 5 cross-sectional studies, and 2 prospective longitudinal studies). Methodological quality scores ranged from 12.5% to 100.0%. Pooled analyses demonstrated a significant association between increased age and body mass and golf-related low back pain in cross-sectional/case-control studies. Prospective data indicated that previous history of back pain predicts future episodes of pain. Conclusion: Individual demographic and anthropometric characteristics may be associated with low back pain, but this does not support a relationship between swing characteristics and the development of golf-related pain. Additional high-quality prospective studies are needed to clarify risk factors for back pain in golfers.
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Sweeney, Emily A., Morgan N. Potter, Richard E. Pimentel, James J. Carollo, and David R. Howell. "SPINAL RANGE OF MOTION AND BACK PAIN IN FEMALE ARTISTIC GYMNASTS DURING BACK WALKOVERS AND BACK HANDSPRINGS." Orthopaedic Journal of Sports Medicine 8, no. 4_suppl3 (April 1, 2020): 2325967120S0022. http://dx.doi.org/10.1177/2325967120s00226.
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Background: Back pain is a common complaint among gymnasts. Gymnastics skills require large amounts of spine flexion, extension, rotation and compression. The combination of these movements in a repetitive fashion during gymnastics may contribute to the development of back pain. Gymnasts perform unique skills on various equipment and surfaces, which makes their movements difficult to evaluate using traditional movement analysis approaches. Hypothesis/Purpose: Our purpose was to measure gymnasts’ movement patterns in their native environment using wearable sensors. Specifically, we examined spine range of motion (ROM) during back walkovers (BWO) and back handsprings (BHS) on the floor and balance beam. We hypothesized that female youth gymnasts with a recent history of back pain would have larger spine ROM compared to gymnasts without back pain when performing these skills. Methods: Female artistic gymnasts ages 8 to 18 years in the Junior Olympic USA Gymnastics program participated in the study. We grouped gymnasts into two groups: those having back pain within the past 12 months and those with no reported back pain in the past 12 months. Gymnasts performed 3 repetitions of BWO and BHS on floor and balance beam while wearing APDM Opal V2 wearable sensors. A BWO requires a controlled bridge kickover while a BHS requires the athlete to jump backwards to her hands (Figure 1). Spine kinematics were then processed via Moveo Explorer. Valid spine sagittal plane maximums, minimums, and ROM of each skill repetition were compared between groups via Kruskal Wallis analysis of variance. Results: Seventeen participants (6 with back pain) completed BWOs and BHSs with acceptable sensor data. There were no demographic differences between the two groups for age, height, weight, competition level, or years of experience (p≥0.129, Table 1). During BWO skills, gymnasts with back pain had greater peak extension and greater ROM in the sagittal plane of the spine (p≤0.032, Figure 2). There were no differences between groups in peak extension, peak flexion, or ROM during BHS skills (p≥0.054, Figure 2). Conclusion: Gymnasts with a history of back pain had increased spinal motion when performing BWO skills. To perform a BWO, gymnasts must have higher levels of shoulder, spine, and hip flexibility, which may relate to back pain. This study suggests the need for future studies to evaluate if increased spinal motion during gymnastics is a contributing factor to the development of back pain. [Figure: see text][Table: see text][Figure: see text]
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George, Steven Z., Cynthia J. Coffman, Kelli D. Allen, Trevor A. Lentz, Ashley Choate, Adam P. Goode, Corey B. Simon, et al. "Improving Veteran Access to Integrated Management of Back Pain (AIM-Back): Protocol for an Embedded Pragmatic Cluster-Randomized Trial." Pain Medicine 21, Supplement_2 (December 2020): S62—S72. http://dx.doi.org/10.1093/pm/pnaa348.
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Abstract Background Coordinated efforts between the National Institutes of Health, the Department of Defense, and the Department of Veterans Affairs have built the capacity for large-scale clinical research investigating the effectiveness of nonpharmacologic pain treatments. This is an encouraging development; however, what constitutes best practice for nonpharmacologic management of low back pain (LBP) is largely unknown. Design The Improving Veteran Access to Integrated Management of Back Pain (AIM-Back) trial is an embedded pragmatic cluster-randomized trial that will examine the effectiveness of two different care pathways for LBP. Sixteen primary care clinics will be randomized 1:1 to receive training in delivery of 1) an integrated sequenced-care pathway or 2) a coordinated pain navigator pathway. Primary outcomes are pain interference and physical function (Patient-Reported Outcomes Measurement Information System Short Form [PROMIS-SF]) collected in the electronic health record at 3 months (n=1,680). A subset of veteran participants (n=848) have consented to complete additional surveys at baseline and at 3, 6, and 12 months for supplementary pain and other measures. Summary AIM-Back care pathways will be tested for effectiveness, and treatment heterogeneity will be investigated to identify which veterans may respond best to a given pathway. Health care utilization patterns (including opioid use) will also be compared between care pathways. Therefore, the AIM-Back trial will provide important information that can inform the future delivery of nonpharmacologic treatment of LBP.
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Frieler, K., M. Mengel, and A. Levermann. "Delaying future sea-level rise by storing water in Antarctica." Earth System Dynamics 7, no. 1 (March 10, 2016): 203–10. http://dx.doi.org/10.5194/esd-7-203-2016.
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Abstract. Even if greenhouse gas emissions were stopped today, sea level would continue to rise for centuries, with the long-term sea-level commitment of a 2 °C warmer world significantly exceeding 2 m. In view of the potential implications for coastal populations and ecosystems worldwide, we investigate, from an ice-dynamic perspective, the possibility of delaying sea-level rise by pumping ocean water onto the surface of the Antarctic ice sheet. We find that due to wave propagation ice is discharged much faster back into the ocean than would be expected from a pure advection with surface velocities. The delay time depends strongly on the distance from the coastline at which the additional mass is placed and less strongly on the rate of sea-level rise that is mitigated. A millennium-scale storage of at least 80 % of the additional ice requires placing it at a distance of at least 700 km from the coastline. The pumping energy required to elevate the potential energy of ocean water to mitigate the currently observed 3 mm yr−1 will exceed 7 % of the current global primary energy supply. At the same time, the approach offers a comprehensive protection for entire coastlines particularly including regions that cannot be protected by dikes.
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Saito, Hiroki, Yoshiteru Watanabe, Toshiki Kutsuna, Toshihiro Futohashi, Yasuaki Kusumoto, Hiroki Chiba, Masayoshi Kubo, and Hiroshi Takasaki. "Spinal movement variability associated with low back pain: A scoping review." PLOS ONE 16, no. 5 (May 24, 2021): e0252141. http://dx.doi.org/10.1371/journal.pone.0252141.
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Objective To identify suggestions for future research on spinal movement variability (SMV) in individuals with low back pain (LBP) by investigating (1) the methodologies and statistical tools used to assess SMV; (2) characteristics that influence the direction of change in SMV; (3) the methodological quality and potential biases in the published studies; and (4) strategies for optimizing SMV in LBP patients. Methods We searched literature databases (CENTRAL, Medline, PubMed, Embase, and CINAHL) and comprehensively reviewed the relevant papers up to 5 May 2020. Eligibility criteria included studies investigating SMV in LBP subjects by measuring trunk angle using motion capture devices during voluntary repeated trunk movements in any plane. The Newcastle-Ottawa risk of bias tool was used for data quality assessment. Results were reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. Results Eighteen studies were included: 14 cross-sectional and 4 prospective studies. Seven linear and non-linear statistical tools were used. Common movement tasks included trunk forward bending and backward return, and object lifting. Study results on SMV changes associated with LBP were inconsistent. Two of the three interventional studies reported changes in SMV, one of which was a randomized controlled trial (RCT) involving neuromuscular exercise interventions. Many studies did not account for the potential risk of selection bias in the LBP population. Conclusion Designers of future studies should recognize that each of the two types of statistical tools assesses functionally different aspects of SMV. Future studies should also consider dividing participants into subgroups according to LBP characteristics, as three potential subgroups with different SMV characteristics were proposed in our study. Different task demands also produced different effects. We found preliminary evidence in a RCT that neuromuscular exercises could modify SMV, suggesting a rationale for well-designed RCTs involving neuromuscular exercise interventions in future studies.
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Siebicke, L., G. Steinfeld, and T. Foken. "CO<sub>2</sub>-gradient measurements using a parallel multi-analyzer setup." Atmospheric Measurement Techniques Discussions 3, no. 5 (October 11, 2010): 4383–421. http://dx.doi.org/10.5194/amtd-3-4383-2010.
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Abstract. Accurate CO2 concentration gradient measurements are needed for the computation of advective flux terms, which are part of the full Net Ecosystem Exchange (NEE) budget equation. A typical draw back of current gradient measurement designs in advection research is the inadequate sampling of complex flow phenomena using too few observation points in space and time. To overcome this draw back, a new measurement design is presented which allows the parallel measurement of several sampling points at a high frequency. Due to the multi-analyzer nature of the design, inter-instrument bias becomes more of a concern compared to conventional setups. Therefore a statistical approach is presented which allows for accurate observations of concentration gradients, which are typically small in relation to analyzer accuracy, to be obtained. This bias correction approach applies a conditional, time dependent signal correction. The correction depends on a mixing index based on cross correlation analysis, which characterizes the degree of mixing of the atmosphere between individual sample points. The approach assumes statistical properties of probability density functions (pdf) of concentration differences between a sample point and the field average which are common to the pdf's from several sample points. The validity of the assumptions made was successfully verified by Large Eddy Simulation (LES) using the model PALM. The study presents concentration time series before and after correction, measured at a 2 m height in the sub-canopy at the FLUXNET spruce forest site Waldstein-Weiden\\-brunnen (DE-Bay), analyzes the dependence of statistical parameters of pdf's from atmospheric parameters such as stratification, quantifies the errors and evaluates the performance of the bias correction approach. The improvements that are achieved by applying the bias correction approach are one order of magnitude larger than possible errors associated with it, which is a strong incentive to use the correction approach. In conclusion, the presented bias correction approach is well suited for – but not limited to – horizontal gradient measurements in a multi-analyzer setup, which would not have been reliable without this approach. Finally, possible future improvements of the bias correction approach are outlined and further fields of application indicated.
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Chiu, Wen-ta, Rachele Hwong, Jason Chiu, Bill Huang, JJ Stewart, Tina T. Tsai, Su-yen Wu, et al. "Quality and patient experience: A six-dimensional approach for the future of healthcare." Journal of Hospital Administration 5, no. 3 (March 1, 2016): 40. http://dx.doi.org/10.5430/jha.v5n3p40.
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The Affordable Care Act (ACA) has significantly altered the American healthcare system. Through the establishment of the ACA, Centers for Medicare and Medicaid Services (CMS) introduced Value-Based Purchasing (VBP), a pay-for-performance program, to the hospital payment system. From a community hospital’s standpoint, a multifaceted approach to quality and patient satisfaction on better managing the health of the community was recognized: what begins in the community ends in the hospital as a valuable indicator for each individual’s well-being. This article depicts the process of utilizing a six-dimensional approach on engaging stakeholders to improve quality of care and patient satisfaction: (1) inpatient, (2) emergency department, (3) employee, (4) physician relationships, (5) outpatient, and (6) community. As the effect of the ACA becomes more prominent, hospitals should maintain their organizational flow and care coordination through the six-dimensional approach to bring patients and their families back to the center of their care.
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Wu, Yingying, Peng Zhao, Hongwei Zhang, Yuan Wang, and Guozhu Mao. "Assessment for Fuel Consumption and Exhaust Emissions of China’s Vehicles: Future Trends and Policy Implications." Scientific World Journal 2012 (2012): 1–8. http://dx.doi.org/10.1100/2012/591343.
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In the recent years, China’s auto industry develops rapidly, thus bringing a series of burdens to society and environment. This paper uses Logistic model to simulate the future trend of China’s vehicle population and finds that China’s auto industry would come into high speed development time during 2020–2050. Moreover, this paper predicts vehicles’ fuel consumption and exhaust emissions (CO, HC, NOx, and PM) and quantificationally evaluates related industry policies. It can be concluded that (1) by 2020, China should develop at least 47 million medium/heavy hybrid cars to prevent the growth of vehicle fuel consumption; (2) China should take the more stringent vehicle emission standard V over 2017–2021 to hold back the growth of exhaust emissions; (3) developing new energy vehicles is the most effective measure to ease the pressure brought by auto industry.
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Frieler, K., M. Mengel, and A. Levermann. "Delaying future sea-level rise by storing water on Antarctica." Earth System Dynamics Discussions 6, no. 2 (October 13, 2015): 1979–97. http://dx.doi.org/10.5194/esdd-6-1979-2015.
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Abstract. Even if greenhouse gas emissions were stopped today sea level would continue to rise for centuries with the long-term sea-level commitment of a two-degree-warmer world significantly exceeding 2 m. In view of the potential implications for coastal populations and ecosystems worldwide we investigate, from an ice-dynamic perspective, the possibility to delay sea-level rise by pumping ocean water onto the surface of the Antarctic Ice Sheet. We find that due to wave propagation ice is discharged much faster back into the ocean than would be expected from a pure advection with surface velocities. The delay time depends strongly on the distance from the coastline at which the additional mass is placed and less strongly on the rate of sea-level rise that is mitigated. A millennium-scale storage of at least 80 % of the additional ice requires placing it at a distance of at least 700 km from the coast line. The pumping energy required to elevate the potential energy of ocean water to mitigate the currently observed 3 mm yr-1 will exceed 7 % of the current global primary energy supply. At the same time the approach may be the only way to protect entire coastlines or specific regions that cannot be protected by dikes.
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Svensson, Lars E. O. "Escaping from a Liquidity Trap and Deflation: The Foolproof Way and Others." Journal of Economic Perspectives 17, no. 4 (November 1, 2003): 145–66. http://dx.doi.org/10.1257/089533003772034934.
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Existing proposals to escape from a liquidity trap and deflation, including my “Foolproof Way,” are discussed in the light of the optimal way to escape. The optimal way involves three elements: (1) an explicit central-bank commitment to a higher future price level; (2) a concrete action that demonstrates the central bank's commitment, induces expectations of a higher future price level and jump-starts the economy; and (3) an exit strategy that specifies when and how to get back to normal. A currency depreciation is a direct consequence of expectations of a higher future price level and hence an excellent indicator of those expectations. Furthermore, an intentional currency depreciation and a crawling peg, as in the Foolproof Way, can implement the optimal way and, in particular, induce the desired expectations of a higher future price level. I conclude that the Foolproof Way is likely to work well for Japan, which is in a liquidity trap now, as well as for the euro area and the United States, in case either would fall into a liquidity trap in the future.
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CURRIE, SHAWN R., and JIANLI WANG. "More data on major depression as an antecedent risk factor for first onset of chronic back pain." Psychological Medicine 35, no. 9 (September 2005): 1275–82. http://dx.doi.org/10.1017/s0033291705004952.
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Background. Few epidemiological studies have examined the temporal relationship between chronic pain and depression using longitudinal data. In the present study, we examined major depression as both an antecedent risk factor and consequence of chronic back pain (CBP) in the general population.Method. Data on 9909 pain-free individuals 15 years and older with no history of back problems were drawn from cycle 1 of the National Population Health Survey and followed up 24 months later. Major depression was assessed using a structured diagnostic interview.Results. At cycle 2, the rate of new cases of CBP in persons who were depressed at cycle 1 was 3·6% compared to 1·1% in non-depressed persons. Compared to pain-free individuals, new cases of CBP were more likely to perceive their health status as poor or fair at cycle 1, were less likely to be working, reported more chronic health problems, and sustained a back or neck injury in the preceding 12 months. After controlling for other factors, pain-free individuals diagnosed as major depressed at cycle 1 were almost three times more likely (OR 2·9, 95% CI 1·2–7·0) to develop CBP at cycle 2.Conclusions. Consistent with other longitudinal studies major depression increases the risk of developing future chronic pain. The causal mechanism linking these conditions is unknown however depression may represent a modifiable risk factor in the development of CBP.
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Ghai, Babita. "Vitamin D Supplementation in Patients with Chronic Low Back Pain: An Open Label, Single Arm Clinical Trial." January 2018 1, no. 21;1 (January 14, 2017): E99—E105. http://dx.doi.org/10.36076/ppj.2017.1.e99.
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Background: Vitamin-D deficiency may possibly be related to chronic low back pain (CLBP). Objective: The study is aimed to assess the impact of vitamin-D supplementation on pain intensity, functional disability, and vitamin-D levels in patients with CLBP. Study Design: Single arm open-label study. Setting: Outpatient pain clinic of a tertiary care hospital. Methods: Sixty-eight eligible patients (CLBP for ≥ 3 months, pain score ≥ 50 on visual analogue scale (VAS) and plasma 25-Hydroxyvitamin D3 levels < 30 ng/mL) were enrolled. Patients were supplemented with 60,000 IU of oral vitamin-D3 given every week for 8 weeks. Efficacy parameters included pain intensity and functional disability measured by VAS and modified Oswestry disability questionnaire (MODQ) scores at baseline, 2, 3, and 6 months post-supplementation. Plasma 25(OH) D3 levels were measured at baseline and 8 weeks. Results: Baseline mean (SD) vitamin-D levels were 12.8 (5.73) ng/mL and increased to 36.07 (12.51) post supplementation (P < 0.01). Forty-five (66%) patients attained normal levels (> 29 ng/mL) post supplementation. Significant reduction in VAS was observed at 2, 3, and 6 months [61 (19), 45 (19), 36 (18)] as compared to 81 (19) at baseline (P ≤ 0.001 at all-time intervals). A significant improvement in the functional ability was also observed at 2, 3, and 6 months [36 (12), 31 (13), and 26 (10)] as compared to baseline 45 (16) (P ≤ 0.001 at all-time intervals). Conclusion: Vitamin-D supplementation in deficient CLBP patients may lead to improvement in pain intensity and functional ability apart from normalization of the levels. Future controlled clinical trials are required to confirm the hypothesis. Key words: Vitamin D, deficiency, screening, low back pain, chronic, supplementation
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Tait, Rich, Ryan Ferretti, Barry Simpson, Jeremy Walker, Jamie Parham, Xiao-Lin Wu, and Stewart Bauck. "34 Present and future of genomic test reporting in the cattle industry." Journal of Animal Science 97, Supplement_2 (July 2019): 19–20. http://dx.doi.org/10.1093/jas/skz122.036.
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Abstract A series of custom low density (LD) SNP genotyping platforms have been created over the years. Recognized by the GeneSeek Genomic Profiler (GGP) nomenclature, these SNP arrays have increased in size as new versions were created, such as: GGP-LD-v1 (n = 8,762), GGP-LD-v2 (n = 20,057), GGP-LD-v3 (n = 26,151), GGP-LD-v4 (n = 30,108), and GGP Bovine 50K (n = 47,843), all of which contained a base of the Illumina Bovine LD array (n = 7,931) and then added SNPs to provide maximum information content (Shannon Entropy) and optimal genomic coverage into target populations without specific restrictions on overlap to historical commercial arrays such as the Illumina Bovine 50K (n = 54,001). Our approach has been to select SNP content which originated on the Illumina Bovine HD array (n = 777,962) or the GGP F250 functional SNP array (n = 221,115). This approach produced GGPs which: 1) have a larger number of SNPs that meet quality control metrics for minor allele frequency and Hardy-Weinberg segregation testing; 2) have superior imputation accuracy to the Illumina HD array in target populations; and 3) have causative SNPs or SNPs in closer LD with causative mutations for functional genomics studies and increased utility across populations. These design features have not always been utilized by users of the GGP portfolio. In some cases, users have imputed from GGP content back to the Illumina Bovine 50K SNP content within their population because that was the earliest process they developed in their evaluation system. This approach ignores the innovation and potential utility designed into the GGP chips for breeders within those organizations. We do not look back to prior SNP arrays for content definition for the purpose of bridging content from current arrays to the past. Instead, our vision is to continue to innovate, on a routine basis, which SNPs we provide to customers, so that their genetic evaluations can continue to evolve and improve into the future.
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Stephens, Phoebe. "Social Finance Investing for a Resilient Food Future." Sustainability 13, no. 12 (June 8, 2021): 6512. http://dx.doi.org/10.3390/su13126512.
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The converging climate, biodiversity, public health and nutrition emergencies highlight the need for more regenerative food systems. Despite the recognition that regenerative food systems enhance resilience, resource efficiency, and equity, they continue to be dwarfed by extractive industrial approaches. One factor that is holding back regenerative food systems is their lack of access to financial capital. In response to this financing gap, social financiers have turned their attention to regenerative food systems. To date, the scholarship exploring the role of social financing in supporting regenerative food systems is limited. Yet, this is an important area of study for understanding the tools that could support pathways towards greater social and ecological resilience in our food systems. This paper develops propositions on the links between social financing and regenerative food systems, with qualitative insights used as illustrations. Six semi-structured interviews were conducted with key stakeholders related to social finance and regenerative food systems in the United States. Additionally, this paper draws on information gathered through presentations from the Regenerative Food System Investment (RSFI) forum. The analysis identified five observations that enrich the social finance and food systems literatures: (1) those who get funded are not necessarily the best placed to advance the goals of regenerative agriculture; (2) tensions exist between the way that scholars and practitioners view social finance; (3) impact metrics are in flux and must be approached thoughtfully; (4) the middle of the food value chain remains severely underfunded; (5) early steps are being taken to maintain diversity that is core to the resilience of regenerative food systems. Topics for further research in this emerging area are identified in the conclusion.
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Gohil, S. "AB1343-HPR A QUALITATIVE REVIEW ASSESSING THEMATIC OUTCOMES FROM THE PHARMACY-LED ADALIMUMAB BIOSIMILAR SWITCH PLAN ACROSS 3 SPECIALITIES; RHEUMATOLOGY, GASTROENTEROLOGY AND DERMATOLOGY AT UNIVERSITY HOSPITALS OF COVENTRY AND WARWICKSHIRE (UHCW)." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1959.1–1960. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3880.
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Background:The advent of biosimilars has heralded a new era for cost effective biologic prescribing in the NHS. As patents expire for originator biologics, less expensive versions are now widely available as biosimilars. Non-medical switches (for reasons unrelated to a patient’s health) ensure prescribing of best value medicines, and cost savings can be redirected to patient care.1This practice resonates with recommendations from Lord Carter’s 2016 report regarding reducing unwarranted variation in the NHS and adopting cost saving opportunities.2In 2018/19, following loss of patent exclusivity for the expensive adalimumab originator biologic, UHCW worked in accordance with national directives to drive forward one of the largest non-medical biosimilar switches.Objectives:This qualitative review aims to explore the success of the adalimumab biosimilar switch and key themes associated with switch backs/refusals across the Rheumatology (R), Gastroenterology (G) and Dermatology (D) specialities at UHCW.Methods:The switch plan occurred between April-December 2019. 403 patients (R;189, G;176, D; 38) were eligible for switch. Patients were informed of the plan in advance via a patient information leaflet/hospital clinic visits. Switch refusals, withheld treatments and cancellations were documented and patients were advised to contact the hospital pharmacy/clinical teams if they encountered any concerns, adverse effects or lack of efficacy post switch. The clinician would then advise on subsequent management.Results:During April-December 2019, 264/403 patients had been successfully switched (R;122, G;109, D;33). 33/403 patients switched back to the originator biologic (R;22, G;10; D;1). Of the 22 rheumatology switch back patients; 6 patients reported injection site pain and variably headache, fatigue, disease relapse, gastrointestinal (GI) upset, erythema; 10=reported lack of efficacy and variably influenza-type symptoms, relapse in associated psoriasis, difficulty in walking/sleeping, hair loss, excessive perspiration, facial cellulitis, foot drop and GI upset; 1=blepharitis;1=latex allergy before injection; 3=later declined switch; 1=damaged two devices and did not wish to continue biosimilar. Of the 10 gastroenterology switch back patients; 1=injection site pain; 2=lack of efficacy; 1=developed needle phobia; 1=latex allergy before injection; 1=switch detrimental to health; 2=unstable disease; 1=insomnia; 1=pregnancy. The 1 dermatology switch back patient reported injection site pain and bleeding.38/403 patients refused the switch and remained on the originator biologic (R;11, G;27, D;0). 29/403 patients had treatment cancellations and were switched to an alternative biologic (R;17, G;9, D;3). 32/403 patients stopped treatment (R;13, G;19, D;0). Treatment was withheld for 7/403 patients (R;4, G;2, D;1).Conclusion:The UHCW adalimumab biosimilar switch plan succeeded in switching a total of 66% of patients; thus an annual cost saving of £73,020. Injection site pain, most likely due to the biosimilar citrate content, and lack of efficacy according to patient perception and subsequent clinical review, were the most predominant causative themes for switch backs. Gastroenterology patients accounted for 71% (27/38) of the total switch refusals. Additional data regarding patient refusals, identifies future opportunities to improve patient counselling and drive further cost savings.References:[1]Azevedo V, et al. Biosimilars: considerations for clinical practice. Considerations in Medicine. 2017;1(1):13–8[2]Lord Carter of Coles. (2016) Operational productivity and performance in English NHS Acute Hospitals: Unwarranted variations [Online]Acknowledgments:Mark Easter, Chief Pharmacist, Hardeep Bagga, Deputy Chief Pharmacist, UHCW Pharmacy Homecare Team, UHCW Specialist Clinical Teams.Disclosure of Interests:None declared
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Schraml, K., B. Thomschitz, B. W. McArdell, C. Graf, and R. Kaitna. "Modeling debris-flow runout patterns on two alpine fans with different dynamic simulation models." Natural Hazards and Earth System Sciences Discussions 3, no. 2 (February 13, 2015): 1397–425. http://dx.doi.org/10.5194/nhessd-3-1397-2015.
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Abstract. Predicting potential deposition areas of future debris-flow events is important for engineering hazard assessment in alpine regions. For this, numerical simulation models are commonly used tools. However, knowledge of appropriate model parameters is essential but often not available. In this study we use two numerical simulation models, RAMMS-DF (Rapid Mass Movement System – Debris Flow) and DAN3D (Dynamic Analysis of Landslides in Three Dimensions), to back-calculate two well-documented debris-flow events in Austria and to compare the range and sensitivity of input parameters for the Voellmy flow model. All simulations are based on the same digital elevation model with a 1 m resolution and similar initial conditions. Our results show that both simulation tools are capable of matching observed deposition patterns. The best fit parameter set of μ [–] and ξ [m s−2] range between 0.07–0.11 and 200–300 m s−2, respectively, for RAMMS-DF, and 0.07–0.08 and 300–400 m s−2, respectively, for DAN3D. Sensitivity analyses show a higher sensitivity of model parameters for the DAN3D model than for the RAMMS-DF model. This study shall contribute to the evaluation of realistic model parameters for simulation of debris-flows in steep mountain catchments and highlights the sensitivity of the models.
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Bossi, G., M. Cavalli, S. Crema, S. Frigerio, B. Quan Luna, M. Mantovani, G. Marcato, L. Schenato, and A. Pasuto. "Multi temporal LiDAR-DTMs as a tool for modelling a complex landslide: a case study in the Rotolon catchment (Eastern Italian Alps)." Natural Hazards and Earth System Sciences Discussions 2, no. 10 (October 10, 2014): 6453–74. http://dx.doi.org/10.5194/nhessd-2-6453-2014.
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Abstract. The geomorphological change detection through the comparison of repeated topographic surveys is a recent approach that benefits greatly from the latest developments in topographical data acquisition techniques. Among them, airborne LiDAR makes the monitoring of geomorphological changes a more reliable and accurate approach for natural hazard and risk management. In this study, two LiDAR-DTMs (2 m resolution) were acquired just before and after a complex 340 000 m3 landslide event (4 November 2010) that generated a debris flow in the channel of the Rotolon catchment (Eastern Italian Alps). The analysis of these data was used to set up the initial condition for the application of a dynamic model. The comparison between the pre- and post-event DTMs allowed to identify erosion and depositional areas and the volume of the landslide. The knowledge of the phenomenon dynamics was the base of a sound back-analysis of the event with the 3-D numerical model DAN3D. This particular code was selected for its capability to modify the rheology and the parameters of the moving mass during run-out, as actually observed along the path of the 2010 debris flow. Nowadays some portions of Mt. Rotolon flank are still moving and show signs of detachment. The same soil parameters used in the back-analysis model could be used to simulate the run-out for possible future landslides allowing to generate reliable risk scenarios useful for awareness of civil defense and strategy on emergency plans.
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Garces, Irina T., Samira Aslanzadeh, Yaman Boluk, and Cagri Ayranci. "Cellulose nanocrystals (CNC) reinforced shape memory polyurethane ribbons for future biomedical applications and design." Journal of Thermoplastic Composite Materials 33, no. 3 (October 30, 2018): 377–92. http://dx.doi.org/10.1177/0892705718806334.
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Shape memory materials are an innovative type of materials that reversibly store a temporary shape and recover back to the original dimensions with the application of an external mechanism such as heat. Shape memory polymers (SMP), specifically thermoplastic SMP (e.g. shape memory polyurethane (SMPU)) have received much attention during the past decade because of the promising future applications and advantages such as ease of processability for thermoplastic SMP (e.g. by 3-D printing), cost, and biocompatibility. In the biomedical field, applications such as stents, surgical sutures, and orthodontic devices, amongst others have been proposed. The addition of fillers to the material can modify the material to improve their load bearing capabilities. Bio-based fillers such as cellulose nanocrystals (CNC) have been proposed in a variety of reinforcing applications. The present work focuses on the experimental description of the addition of nonmodified CNC to SMPU. The work studied the effect on melt-extruded ribbons, for 0, 0.5, 1, 2, and 4 wt%. An increase of yield point, toughness, flexural modulus, recovery rate, and decrease of total time showed that SMPU/CNC nanocomposites are a potential candidate to use in future biomedical applications.
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Johnston, S. D., J. Gosalvez, and W. V. Holt. "046. FUTURE PROOFING AUSTRALIA'S MAMMALIAN BIODIVERSITY USING GENOME RESOURCE BANKING AND ART: WHERE ARE WE UP TO?" Reproduction, Fertility and Development 21, no. 9 (2009): 11. http://dx.doi.org/10.1071/srb09abs046.
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The establishment of a functional genome resource bank for the genetic management and future proofing of Australian native mammals sounds great in theory, but what is the reality of this idea. In order to understand the current rate of progress in this area, we will present an overview of the inherent structural and physiological limitations of non-eutherian mammalian reproduction in terms of gamete biology and ART. For the male, these include (1) an unique mode of spermatid condensation that imparts the need for major structural changes to sperm morphology during epididymal transit, (2) a lack of cysteine protamines and disulphide bonds in the sperm chromatin that predisposes the nucleus to post-thaw chromatin relaxation, (3) an extremely stable acrosome, which to date, has not been possible to experimentally react in vitro, (4) unusual lipid composition in the plasma membrane that potentially makes the sperm cell resistant to cold shock trauma and (5) the need, in some species, for extremely high concentrations of cryoprotectant, that paradoxically, appear to be cytotoxic to the spermatozoon. Female limitations include, (1) the production of a large yolky oocyte and resulting embryo, making it difficult to cryopreserve, (2) a small and technically challenging complex reproductive tract that makes gamete recovery and artificial insemination problematic and (3) a general lack of information on marsupial reproductive physiology and behaviour that has hindered the development of protocols for timed induction of oestrus and ovulation. We shall also identify, socio-political and ethical limitations holding back the application of assisted breeding technology in these species.
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Bihl, Trevor, Todd Jenkins, Chadwick Cox, Ashley DeMange, Kerry Hill, and Edmund Zelnio. "From Lab to Internship and Back Again: Learning Autonomous Systems through Creating a Research and Development Ecosystem." Proceedings of the AAAI Conference on Artificial Intelligence 33 (July 17, 2019): 9635–43. http://dx.doi.org/10.1609/aaai.v33i01.33019635.
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As research and development (R&D) in autonomous systems progresses further, more interdisciplinary knowledge is needed from domains as diverse as artificial intelligence (AI), bi-ology, psychology, modeling and simulation (M&S), and robotics. Such R&D efforts are necessarily interdisciplinary in nature and require technical as well as further soft skills of teamwork, communication and integration. In this paper, we introduce a 14 week, summer long internship for developing these skills in undergraduate science and engineering interns through R&D. The internship was designed to be modular and divided into three parts: training, innovation, and application/integration. The end result of the internship was 1) the development of an M&S ecosystem for autonomy concepts, 2) development and robotics testing of reasoning methods through both Bayesian methods and cognitive models of the basal ganglia, and 3) a process for future internships within the modular construct. Through collaboration with full-time professional staff, who actively learned with the interns, this internship incorporates a feedback loop to educate and per-form fundamental R&D. Future iterations of this internship can leverage the M&S ecosystem and adapt the modular internship framework to focus on different innovations, learning paradigms, and/or applications.
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Garrity, Brigid M., Sara J. Singer, Erin Ward, Lucia Bastianelli, Jay G. Berry, Charis Crofton, Laurie Glader, Elizabeth L. Casto, and Joanne E. Cox. "Parent Perspectives on Short-Term Recovery After Spinal Fusion Surgery in Children With Neuromuscular Scoliosis." Journal of Patient Experience 7, no. 6 (December 2020): 1369–77. http://dx.doi.org/10.1177/2374373520972570.
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Family perspectives on short-term recovery after spinal fusion for neuromuscular scoliosis are essential for improving patient outcomes. Semistructured interviews were conducted with 18 families of children within 3 months after spinal fusion performed August 2017 to January 2019 at a children’s hospital. Interviews were recorded, transcribed, and coded line-by-line by 2 independent reviewers using grounded theory to identify themes. Five themes emerged among families when reflecting back on the postoperative recovery: (1) communicating and making shared decisions regarding postoperative care in a patient- and family-centered manner, (2) setting hospital discharge goals and being ready for discharge, (3) planning for transportation from hospital to home, (4) acquiring supports for caregiving at home after discharge, and (5) anticipating a long recovery at home. Important family perceptions were elicited about the recovery of children from spinal fusion for neuromuscular scoliosis that will inform better perioperative planning for clinicians, future patients, and their families.
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Jinnah, Sikina, Simon Nicholson, David R. Morrow, Zachary Dove, Paul Wapner, Walter Valdivia, Leslie Paul Thiele, et al. "Governing Climate Engineering: A Proposal for Immediate Governance of Solar Radiation Management." Sustainability 11, no. 14 (July 20, 2019): 3954. http://dx.doi.org/10.3390/su11143954.
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Solar radiation management (SRM) technologies would reflect a small amount of incoming solar radiation back into space before the radiation can warm the planet. Although SRM may emerge as a useful component of a global response to climate change, there is also good reason for caution. In June 2017, the Academic Working Group on Climate Engineering Governance released a policy report, “Governing Solar Radiation Management”, which developed a set of objectives to govern SRM in the near-term future: (1) keep mitigation and adaptation first; (2) thoroughly and transparently evaluate risks, burdens, and benefits; (3) enable responsible knowledge creation; and (4) ensure robust governance before any consideration of deployment. To advance the governance objectives identified above, the working group developed twelve recommendations, grouped into three clusters: (1) create politically legitimate deliberative bodies; (2) leverage existing institutions; and (3) make research transparent and accountable. This communication discusses the rationale behind each cluster and elaborates on a subset of the recommendations from each cluster.
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Bork, Jacqueline, Kimberly C. Claeys, J. Kristie Johnson, Jennifer Jones, Uzoamaka Obiekwe, Martha Lusby, Emily Heil, and Surbhi Leekha. "2362. Back to the Future: The Impact of Multi-Step Algorithm C. difficile Testing at a Large Tertiary Medical Center." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S813—S814. http://dx.doi.org/10.1093/ofid/ofz360.2040.
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Abstract Background Antibiotic stewardship and infection control programs rely on C. difficile infection (CDI) test results to measure CDI incidence in the hospital setting. C. difficile carriage is common and distinguishing infection from colonization is difficult with the highly sensitive nucleic acid amplification testing (NAAT) commonly used. Current guidelines recommend a multi-step algorithm for testing. The impact on patient outcomes and CDI metrics are largely unknown. Methods This was a pre-post study at the University of Maryland Medical Center, evaluating the impact of a CDI testing strategy (introduced October 2018) that simultaneously reported NAAT and confirmatory enzyme immunoassay (EIA) when used with existing best practice alerts for appropriate testing. Pre-intervention (November 2017–September 2018) and post intervention (October 2018–March 2019) periods were compared for mean CDI incidence (CDI per 10,000 admissions) defined by: (1) positive NAAT, (2) reported CDI (last positive test), and (3) treated CDI (receiving oral vancomycin). Both community and hospital-onset cases were included. The NAAT CDI incidence was used as the pre-intervention comparison for all 3 measures. In addition, oral vancomycin days of therapy (DOT) per 1,000 patient-days (PD) was compared. Pre–post comparisons of mean CDI incidence and mean DOT rates were done using Student t-test. Results There were 3,237 samples tested (2,269 pre and 968 post-intervention) with 376 NAAT positive (262 pre and 114 post-intervention). Of the 99 tests with reflex EIA, there were 74 discordant tests (NAAT +/EIA -) with 35 (47%) treated for CDI. Mean NAAT CDI incidence pre-intervention was 54 per 10,000 admissions. Post-intervention mean CDI incidence decreased as follows: 45 NAAT CDI per 10,000 admissions (P = 0.13), 15 reported CDI per 1000 admissions (P < 0.0001), and 28 treated CDI per 10,000 admissions (P = 0.0007). Oral vancomycin DOT per 1,000 PD decreased from 16 to 9 (P = 0.0002). Conclusion C. difficile NAAT testing with confirmatory EIA, in combination with best practice alert, decreased reported and treated cases of CDI, which may distinguish infection vs. colonization and avoid unnecessary treatment, beyond that achieved with alerts that improve appropriate patient selection for testing. Disclosures All authors: No reported disclosures.
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Davies, Gail, Beth Greenhough, Pru Hobson-West, and Robert G. W. Kirk. "Science, Culture, and Care in Laboratory Animal Research." Science, Technology, & Human Values 43, no. 4 (February 13, 2018): 603–21. http://dx.doi.org/10.1177/0162243918757034.
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The principles of the 3Rs—replacement, refinement, and reduction—strongly shape discussion of methods for performing more humane animal research and the regulation of this contested area of technoscience. This special issue looks back to the origins of the 3Rs principles through five papers that explore how it is enacted and challenged in practice and that develop critical considerations about its future. Three themes connect the papers in this special issue. These are (1) the multiplicity of roles enacted by those who use and care for animals in research, (2) the distribution of “feelings that matter” across species and spaces of laboratory animal practice, and (3) the growing importance of “cultures of care” in animal research.
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Kobayashi, Kazuyoshi, Shiro Imagama, Kei Ando, Masaaki Machino, Satoshi Tanaka, Masayoshi Morozumi, Shunsuke Kanbara, et al. "Locomotive Syndrome Stage 1 Predicts Significant Worsening of Future Motor Performance: The Prospective Yakumo Study." BioMed Research International 2019 (October 3, 2019): 1–7. http://dx.doi.org/10.1155/2019/1970645.
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Purpose. Aging of society has increased the need for prolongation of a healthy lifespan through maintenance of physical function. Prediction of future physical function may be possible by screening for stage 1 locomotive syndrome (LS). In this prospective study, we examined the influence of LS stage 1 at baseline (2011) on physical performance after 5 years (2016) in a community-dwelling cohort. Methods. The participants were elderly adults aged >40 years who attended public health checkups as part of the Yakumo Study. LS screening in 2011 and 2016 was performed using the 25-question geriatric locomotive function scale (GLFS-25), the stand-up test, and the two-step test. LS of stage 1 or 2 was defined if the participant met the criteria in any of the three tests. Participants not meeting LS criteria were defined as the no risk group. Physical performance tests (10 m gait time, back muscle strength, 3 m TUG, and maximum stride) were also performed in 2011 and 2016. Results. A total of 113 subjects (49 males, 64 females; average age 65.0 years) were followed from 2011 to 2016. At baseline, 73 (65%) had no risk, 29 (25%) had stage 1 LS, and 11 (10%) had stage 2 LS. Five years later, 51 (45%) had no risk, 45 (40%) had stage 1 LS, and 17 (15%) had stage 2 LS. Of the 73 subjects with no risk at baseline, 23 (32%) had stage 1 LS and 1 (1%) had stage 2 LS after 5 years. The baseline stage 1 LS group had significantly worse physical performance after 5 years, compared to the baseline no risk group (p<0.05). Conclusions. This longitudinal study showed that stage 1 LS screening is important for prevention of motor dysfunction in middle-aged and elderly people.
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Malcolm, Annie. "The past at the edge of the future: Landscape painting and contemporary places." Journal of Contemporary Chinese Art 7, no. 2-3 (December 1, 2020): 221–40. http://dx.doi.org/10.1386/jcca_00027_1.
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In this article, I offer an ethnographic account of Wutong Shan, and engage landscape painting as an interpretative device. Wutong Shan represents a unique phenomenon of urban transformation in that its residents cultivate a life harkening back to a rural past in an attempt to build a utopia unfettered by the deafening noise of modernity, which can easily be found down the road in Shenzhen, China’s newest city. Similar to what landscape painters throughout history have created through image, Wutong residents create a world of retreat, escape and natural beauty in a space at the edge of the urban. Both a landscape painting and this ethnographic place are built through a set of creative acts, a sense of self-cultivation, and a desire for escape. In Wutong Shan, the other side of the creative process is a livable environment rather than an art object. One of the ways I read landscape painting to understand Wutong Shan is by thinking with contemporary Chinese art works that, through illusion, revisit the landscape in light of industrial urbanization. I bring together three strains of thinking: (1) my contemporary ethnographic research on Wutong Art Village, (2) understandings of Chinese landscape paintings and their associated conceptions of nature and utopia and (3) contemporary art that renegotiates the landscape form, analysed through the emergent field of eco-art history.
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Bürger, G., S. R. Sobie, A. J. Cannon, A. T. Werner, and T. Q. Murdock. "Downscaling Extremes: An Intercomparison of Multiple Methods for Future Climate." Journal of Climate 26, no. 10 (May 8, 2013): 3429–49. http://dx.doi.org/10.1175/jcli-d-12-00249.1.
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Abstract This study follows up on a previous downscaling intercomparison for present climate. Using a larger set of eight methods the authors downscale atmospheric fields representing present (1981–2000) and future (2046–65) conditions, as simulated by six global climate models following three emission scenarios. Local extremes were studied at 20 locations in British Columbia as measured by the same set of 27 indices, ClimDEX, as in the precursor study. Present and future simulations give 2 × 3 × 6 × 8 × 20 × 27 = 155 520 index climatologies whose analysis in terms of mean change and variation is the purpose of this study. The mean change generally reinforces what is to be expected in a warmer climate: that extreme cold events become less frequent and extreme warm events become more frequent, and that there are signs of more frequent precipitation extremes. There is considerable variation, however, about this tendency, caused by the influence of scenario, climate model, downscaling method, and location. This is analyzed using standard statistical techniques such as analysis of variance and multidimensional scaling, along with an assessment of the influence of each modeling component on the overall variation of the simulated change. It is found that downscaling generally has the strongest influence, followed by climate model; location and scenario have only a minor influence. The influence of downscaling could be traced back in part to various issues related to the methods, such as the quality of simulated variability or the dependence on predictors. Using only methods validated in the precursor study considerably reduced the influence of downscaling, underpinning the general need for method verification.
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Chen, Xiaoxue, Lianwen Jin, Yuanzhi Zhu, Canjie Luo, and Tianwei Wang. "Text Recognition in the Wild." ACM Computing Surveys 54, no. 2 (April 2021): 1–35. http://dx.doi.org/10.1145/3440756.
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The history of text can be traced back over thousands of years. Rich and precise semantic information carried by text is important in a wide range of vision-based application scenarios. Therefore, text recognition in natural scenes has been an active research topic in computer vision and pattern recognition. In recent years, with the rise and development of deep learning, numerous methods have shown promising results in terms of innovation, practicality, and efficiency. This article aims to (1) summarize the fundamental problems and the state-of-the-art associated with scene text recognition, (2) introduce new insights and ideas, (3) provide a comprehensive review of publicly available resources, and (4) point out directions for future work. In summary, this literature review attempts to present an entire picture of the field of scene text recognition. It provides a comprehensive reference for people entering this field and could be helpful in inspiring future research. Related resources are available at our GitHub repository: https://github.com/HCIILAB/Scene-Text-Recognition.
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Monroy-Velázquez, Luz Veronica, Rosa Elisa Rodríguez-Martínez, and Fernando Alvarez. "Taxonomic richness and abundance of cryptic peracarid crustaceans in the Puerto Morelos Reef National Park, Mexico." PeerJ 5 (June 15, 2017): e3411. http://dx.doi.org/10.7717/peerj.3411.
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Background and Aims Cryptic peracarids are an important component of the coral reef fauna in terms of diversity and abundance, yet they have been poorly studied. The aim of this study was to evaluate the taxonomic richness and abundance of cryptic peracarids in coral rubble in the Puerto Morelos Reef National Park, Mexico (PMRNP), and their relationship with depth. Methods Three reef sites were selected: (1) Bonanza, (2) Bocana, and (3) Jardines. At each site six kilograms of coral rubble were collected over four sampling periods at three depths: 3 m (back-reef), 6–8 m (fore-reef), and 10–12 m (fore-reef). Results A total of 8,887 peracarid crustaceans belonging to 200 taxa distributed over five orders and 63 families was obtained; 70% of the taxa were identified to species and 25% to genus level. Fifty species of those collected represent new records for the Mexican Caribbean Sea. Isopoda was the most speciose order while Tanaidacea was the most abundant. Discussion Cryptic peracarid taxonomic richness and abundance were related to depth with higher values of both parameters being found in the shallow (3 m) back-reef, possibly due to a higher reef development and a greater accumulation of coral rubble produced during hurricanes. Peracarid data obtained in the present study can be used as a baseline for future monitoring programs in the PMRNP.
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Iuchi, Kanako, and Elizabeth Maly. "Roles of People, Community and Planning in Recovery After Mega-Disasters: A Symposium Synopsis." Journal of Disaster Research 11, no. 3 (June 1, 2016): 512–16. http://dx.doi.org/10.20965/jdr.2016.p0512.
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The concept of ‘building back better’ is being mainstreamed in international development to minimize future devastation from natural disasters. This paper reports on presentations and discussions from the Second International Symposium on Recovery after Mega Disasters: People, Community and Planning, held March 16, 2015 during the Third World Conference on Disaster Risk Reduction. International experts, including practitioners and researchers, presented varied recovery efforts and insights. The three following principles emerged from the symposium. 1) Relocation, compact (re)development, renewable energy, and flood controls are key policy focuses in recovery plans, and require careful individual and community involvement, planning designs, and information sharing. 2) Identifying unique local resources is key for successful recovery and can help formulate innovative strategies. 3) As rebuilding that considers local culture, systems, and groups aids in resilient recovery, planning practitioners need in-depth understanding of local contexts to derive better solutions. Given these three principles, participants agreed that at its core, the concept of ‘building back better’ requires tailor-made planning designs and processes.
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Sheehan, Mary C. "Climate Change and Human Well-Being in the 2020s: Lessons From 2020." International Journal of Health Services 51, no. 3 (April 28, 2021): 281–86. http://dx.doi.org/10.1177/00207314211012155.
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Behind the coronavirus headlines the year 2020 set multiple extreme weather records, including unprecedented wildfires in Australia and California, massive flooding in China, and back-to-back hurricanes in Central America. The impacts on the well-being of local populations have been devastating. We reviewed these extreme weather events, together with the year’s newly published climate and health science reports, and identified three important themes for building health resilience in the decade ahead: (1) preparing for greater magnitude and intensity of climate hazards, extreme events, and population health impacts; (2) better anticipating cascading and compound impacts on population well-being, particularly for the most vulnerable; and (3) identifying appropriate, effective preparedness tools and strategies. While decarbonizing the economy is the urgent goal to protect both human and planetary health from a changing climate, 2020 demonstrates that recognizing the likely magnitude and complexity of future extreme weather events, and preparing local public health agencies and communities with the knowledge and tools to respond to them, will be essential in this critical decade.
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Li, Linda C., and Claire Bombardier. "Physical Therapy Management of Low Back Pain: An Exploratory Survey of Therapist Approaches." Physical Therapy 81, no. 4 (April 1, 2001): 1018–28. http://dx.doi.org/10.1093/ptj/81.4.1018.
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Abstract Background and Purpose. Since the release of acute low back pain management guidelines in 1994, little was known about the effect of these guidelines on clinical practice. The purpose of this study was to examine physical therapists' reported management of acute and subacute lumbar impairment. Subjects. One in 10 registered physical therapists who were randomly selected from southern Ontario, Canada, (n=454) and all registered physical therapists from northern Ontario (n=331) were surveyed. Methods. In the questionnaire, case scenarios covered 3 areas related to the management of lumbar impairment: (1) physical examination, (2) treatment and recommendations, and (3) therapists' beliefs regarding its management. Results. Five hundred sixty-nine questionnaires were returned (response rate=72.5%). Only data obtained for therapists (n=274) whose weekly workload included more than 10% of people with lumbar impairment were used in the analysis. Overall, patient education, exercise, and electrotherapeutic and thermal modalities were the preferred interventions for acute lumbar impairment (symptom onset of less than 5 weeks) with or without sciatica, whereas exercise and work modification were preferred for subacute lumbar impairment (symptom onset of 5 weeks or longer). There was a trend of using electrotherapeutic and thermal modalities of uncertain effectiveness. Only 46.3% of the therapists agreed or strongly agreed that practice guidelines were useful for managing lumbar impairment. Discussion and Conclusion. Although the physical therapists surveyed, in general, followed the guidelines in managing acute lumbar impairment, they felt uncertain regarding the value of practice guidelines. Future research should focus on identifying effective treatment approaches and exploring the effectiveness of practice guidelines.
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Sole, Mary Lou. "How I Learned My ABCs: Action, Back to Basics, Collaboration, Discovery." American Journal of Critical Care 19, no. 4 (July 1, 2010): 326–34. http://dx.doi.org/10.4037/ajcc2010402.
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Background Research is essential to generate the scientific evidence for critical care nursing practice, but it is challenging to conduct research in the busy critical care environment. The challenges are even greater in a setting with limited resources for research and where nurses have not typically conducted independent clinical studies. Objectives To detail a successful research trajectory for studying the ABCs of patient care in the critically ill: airway, breathing, and circulation. Methods After initial studies on circulation were conducted, the research was narrowed to focus on airway management. Airway management may be a key factor in preventing ventilator-associated pneumonia because aspiration of colonized oral, gastric, and tracheal secretions is the primary cause of ventilator-associated pneumonia. Multiple descriptive, pilot, and interventional studies have been conducted; findings from each have contributed to future studies. Results Other ABCs were critical to this research success: action, back to basics, collaboration, and discovery. It is important for researchers to be self-motivated and to take initiative to develop skills and resources for conducting clinical studies. Several guiding principles help to promote success in research: (1) generate research ideas grounded in observation and clinical practice, (2) collaborate with others, and (3) establish affiliations and partnerships. Discovery occurs in many ways: new findings to guide practice and research, resources to conduct the study, and self-discovery. Conclusions Nursing research is not easy. However, determination and resources help nursing researchers achieve success.
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Brevik, E. C., and T. J. Sauer. "The past, present, and future of soils and human health studies." SOIL 1, no. 1 (January 6, 2015): 35–46. http://dx.doi.org/10.5194/soil-1-35-2015.
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Abstract. The idea that human health is tied to the soil is not a new one. As far back as circa 1400 BC the Bible depicts Moses as understanding that fertile soil was essential to the well-being of his people. In 400 BC the Greek philosopher Hippocrates provided a list of things that should be considered in a proper medical evaluation, including the properties of the local ground. By the late 1700s and early 1800s, American farmers had recognized that soil properties had some connection to human health. In the modern world, we recognize that soils have a distinct influence on human health. We recognize that soils influence (1) food availability and quality (food security), (2) human contact with various chemicals, and (3) human contact with various pathogens. Soils and human health studies include investigations into nutrient supply through the food chain and routes of exposure to chemicals and pathogens. However, making strong, scientific connections between soils and human health can be difficult. There are multiple variables to consider in the soil environment, meaning traditional scientific studies that seek to isolate and manipulate a single variable often do not provide meaningful data. The complete study of soils and human health also involves many different specialties such as soil scientists, toxicologists, medical professionals, anthropologists, etc. These groups do not traditionally work together on research projects, and do not always effectively communicate with one another. Climate change and how it will affect the soil environment/ecosystem going into the future is another variable affecting the relationship between soils and health. Future successes in soils and human health research will require effectively addressing difficult issues such as these.
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Brevik, E. C., and T. J. Sauer. "The past, present, and future of soils and human health studies." SOIL Discussions 1, no. 1 (May 14, 2014): 51–80. http://dx.doi.org/10.5194/soild-1-51-2014.
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Abstract. The idea that human health is tied to the soil is not a new one. As far back as circa 1400 BC the Bible depicts Moses as understanding that fertile soil was essential to the well-being of his people. In 400 BC the Greek philosopher Hippocrates provided a list of things that should be considered in a proper medical evaluation, including the properties of the local ground. By the late 1700 and early 1800s, American farmers had recognized that soil properties had some connection to human health. In the modern world, we recognize that soils have a distinct influence on human health. We recognize that soils influence (1) food availability and quality (food security), (2) human contact with various chemicals, and (3) human contact with various pathogens. Soils and human health studies include investigations into nutrient supply through the food web and routes of exposure to chemicals and pathogens. However, making strong, scientific connections between soils and human health can be difficult. There are multiple variables to consider in the soil environment, meaning traditional scientific studies that seek to isolate and manipulate a single variable often do not provide meaningful data. The complete study of soils and human health also involves many different specialties such as soil scientists, toxicologists, medical professionals, anthropologists, etc. These groups do not traditionally work together on research projects, and do not always effectively communicate with one another. Climate change and how it will affect the soil environment/ecosystem going into the future is another variable affecting the relationship between soils and health. Future successes in soils and human health research will require effectively addressing difficult issues such as these.
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Kilgas, Matthew A., and Steven J. Elmer. "Back to the future! Revisiting the physiological cost of negative work as a team-based activity for exercise physiology students." Advances in Physiology Education 41, no. 1 (March 1, 2017): 120–29. http://dx.doi.org/10.1152/advan.00158.2016.
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We implemented a team-based activity in our exercise physiology teaching laboratory that was inspired from Abbott et al.’s classic 1952 Journal of Physiology paper titled “The physiological cost of negative work.” Abbott et al. connected two bicycles via one chain. One person cycled forward (muscle shortening contractions, positive work) while the other resisted the reverse moving pedals (muscle lengthening contractions, negative work), and the cost of work was compared. This study was the first to link human whole body energetics with isolated muscle force-velocity characteristics. The laboratory activity for our students ( n = 35) was designed to reenact Abbott et al.’s experiment, integrate previously learned techniques, and illustrate differences in physiological responses to muscle shortening and lengthening contractions. Students (11–12 students/laboratory section) were split into two teams (positive work vs. negative work). One student from each team volunteered to cycle against the other for ~10 min. The remaining students in each team were tasked with measuring: 1) O2 consumption, 2) heart rate, 3) blood lactate, and 4) perceived exertion. Students discovered that O2 consumption during negative work was about one-half that of positive work and all other physiological parameters were also substantially lower. Muscle lengthening contractions were discussed and applied to rehabilitation and sport training. The majority of students (>90%) agreed or strongly agreed that they stayed engaged during the activity and it improved their understanding of exercise physiology. All students recommended the activity be performed again. This activity was engaging, emphasized teamwork, yielded clear results, was well received, and preserved the history of classic physiological experiments.
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Stefansdottir, R., H. S. Gundersen, H. Haraldsson, V. Rognvaldsdottir, A. S. Lundervold, S. Gestsdottir, S. L. Gudmundsdottir, K. Y. Chen, R. J. Brychta, and E. Johannsson. "0337 Association Between Free-living Sleep and Memory and Attention in Healthy Adolescents." Sleep 43, Supplement_1 (April 2020): A128. http://dx.doi.org/10.1093/sleep/zsaa056.334.
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Abstract Introduction Sleep is important for people of all ages, especially children during development. However, adolescents often sleep less than the recommended eight hours per night. Clinical trials have found that even partial sleep deprivation- shorter than the recommended duration- can reduce cognitive function in adolescents. The association between objectively measured free-living sleep and cognition function in adolescents has not been studied. Methods Free-living sleep duration and sleep efficiency were measured over one week with wrist actigraphy in 199 healthy normal adolescents (140 girls, mean±SD, 17.7±0.3 years). The day after the sleep measurement concluded, sustained attention was assessed with a validated Posner cue-target task, and working memory was measured with an n-back task. Associations between sleep measures and response times during attention and memory tasks were explored with multiple linear regression adjusted for task accuracy. Results Over the entire week, participants’ average sleep duration was 6.2±0.7 h/night and average sleep efficiency was 88±4.4% and averages for sleep the night prior to the cognitive testing were similar. Response times on memory (1-back: 420.6±73.9, 2-back: 522.6±101.9, and 3-back: 551.8±137.2 msec) and attention tasks (valid cue: 309±31.2, invalid cue: 365.8±36, and no cue: 393.6±38.9 msec) were similar to previous reports and not associated with average weekly sleep measures. Sleep duration of the night before cognitive testing was negatively associated with response times for the most challenging memory task (3-back; p=0.02). However, sleep measures of the night before did not correlate with any of the attention task scores. Conclusion Our data suggests that performance on difficult memory tasks may be negatively impacted by shorter free-living sleep durations the night prior to testing, even in healthy adolescents who average less than the recommended amount of sleep. Future studies should explore whether recovery sleep or other improvements in sleep habit might mitigate such effects on memory. Support The Eimskip University of Iceland Fund, Icelandic Centre for Research, National Institute of Diabetes and Digestive and Kidney Diseases.
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Imran Farooqui, Sumaira, Zulekha Saleem, Ashbeel John Edgar, and Shahida Abbass. "ASSESSMENT OF HAMSTRING FLEXIBILITY RETENTION THROUGH SIT-AND-REACH BOX IN UNIVERSITY STUDENTS WITH NONSPECIFIC LOW BACK PAIN." Pakistan Journal of Rehabilitation 5, no. 1 (January 1, 2016): 31–38. http://dx.doi.org/10.36283/pjr.zu.5.1/006.
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OBJECTIVES Administrationof sit and reach (SR) box as an intervention tool for retaining the hamstring flexibility as a treatment regime in order to prevent as well predict future low back pain complications. Improvement of hamstring flexibility through SR box, administrationof SR box as an assessment tool in patients with reduced hamstring flexibility causing low back pain complications. Also implementation of SR box for training purpose in clinical practice to evaluate the efficacy of the SR box in retention of hamstring flexibility in both genders. STUDY DESIGN A quantitative experimental study inclusive of simple random sampling was done. The independent variables were age and gender. Flexibility retention and treatment were the dependent variables which were assessed by a Sit-and-reach box. MEASUREMENTS The subject pool for this study consisted of 40 volunteers that were selected on the basis of simple random sampling and were recruited in the study after assessing hamstring tightness through toe-touching, straight leg raise and piriformis test to exclude any specific pathology or disorders. RESULTS Flexibility showed marked increase in most of the applicants on 5th trial after a 4 week training regime by sit and reach box. CONCLUSION Achievements in flexibility are preserved for no less than 2 weeks after a stretching program. It additionally created the impression that 2 sets; each consisting of 3 repetitions of a sit-and-reach test is adequate for boosting extensive increment in flexibility. KEYWORDS Sit-And-Reach, Stretching, Flexibility, Hamstring, Low Back Pain, Straight Leg Raise.
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Gómez-Galán, Marta, José Pérez-Alonso, Ángel-Jesús Callejón-Ferre, and Julián Sánchez-Hermosilla-López. "Assessment of Postural Load during Melon Cultivation in Mediterranean Greenhouses." Sustainability 10, no. 8 (August 2, 2018): 2729. http://dx.doi.org/10.3390/su10082729.
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Health and safety at work directly influence the development of sustainable agriculture. In the agricultural sector, many farm workers suffer musculoskeletal disorders caused by forced posture. The objective of this research is to assess working postures during melon cultivation in Almería-type greenhouses. The Ovako Working Posture Assessment System (OWAS) has been used with pictures of the tasks. The variables studied by multiple correspondence analysis were as follows: Subtask, Posture code, Back, Arms, Legs, Load, Risk, and Risk combination. The OWAS analysis showed that 47.57% of the postures were assessed as risk category 2, 14.32% as risk category 3, 0.47% as risk category 4, and the rest as risk category 1. Corrective measures should be implemented immediately, as soon as possible, or in the near future, depending on the risks detected.
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Gallego, M. Angeles, Axel Timmermann, Tobias Friedrich, and Richard E. Zeebe. "Drivers of future seasonal cycle changes in oceanic <i>p</i>CO<sub>2</sub>." Biogeosciences 15, no. 17 (September 3, 2018): 5315–27. http://dx.doi.org/10.5194/bg-15-5315-2018.
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Abstract. Recent observation-based results show that the seasonal amplitude of surface ocean partial pressure of CO2 (pCO2) has been increasing on average at a rate of 2–3 µatm per decade (Landschützer et al., 2018). Future increases in pCO2 seasonality are expected, as marine CO2 concentration ([CO2]) will increase in response to increasing anthropogenic carbon emissions (McNeil and Sasse, 2016). Here we use seven different global coupled atmosphere–ocean–carbon cycle–ecosystem model simulations conducted as part of the Coupled Model Intercomparison Project Phase 5 (CMIP5) to study future projections of the pCO2 annual cycle amplitude and to elucidate the causes of its amplification. We find that for the RCP8.5 emission scenario the seasonal amplitude (climatological maximum minus minimum) of upper ocean pCO2 will increase by a factor of 1.5 to 3 over the next 60–80 years. To understand the drivers and mechanisms that control the pCO2 seasonal amplification we develop a complete analytical Taylor expansion of pCO2 seasonality in terms of its four drivers: dissolved inorganic carbon (DIC), total alkalinity (TA), temperature (T), and salinity (S). Using this linear approximation we show that the DIC and T terms are the dominant contributors to the total change in pCO2 seasonality. To first order, their future intensification can be traced back to a doubling of the annual mean pCO2, which enhances DIC and alters the ocean carbonate chemistry. Regional differences in the projected seasonal cycle amplitude are generated by spatially varying sensitivity terms. The subtropical and equatorial regions (40∘ S–40∘ N) will experience a ≈30–80 µatm increase in seasonal cycle amplitude almost exclusively due to a larger background CO2 concentration that amplifies the T seasonal effect on solubility. This mechanism is further reinforced by an overall increase in the seasonal cycle of T as a result of stronger ocean stratification and a projected shoaling of mean mixed layer depths. The Southern Ocean will experience a seasonal cycle amplification of ≈90–120 µatm in response to the mean pCO2-driven change in the mean DIC contribution and to a lesser extent to the T contribution. However, a decrease in the DIC seasonal cycle amplitude somewhat counteracts this regional amplification mechanism.