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1

Sakhawalkar, Neha. "Hub Proteins, Paralogs, and Unknown Proteins in Bacterial Interaction Networks." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4730.

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Proteins are the functional units of cells. However, a major portion of the proteome does not have a known functional annotation. This dissertation explores protein -protein interactions, involving these uncharacterized or unknown function proteins. Initially, protein – protein interactions were tested and analyzed for paralogous proteins in Escherichia coli. To expand this concept further and to get an overview, protein – protein interactions were analyzed using ‘comparative interactomics’ for four pathogenic bacterial species including Escherichia coli, Yersinia pestis, Vibrio cholerae and S
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2

Nauli, Sehat. "Folding kinetics and redesign of Peptostreptococcal protein L and G /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/9237.

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3

Chilukuri, Lakshmi N. "The effect of pressure on DNA-binding proteins from piezosensitive and piezophilic bacteria /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1998. http://wwwlib.umi.com/cr/ucsd/fullcit?p3035908.

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4

Bignell, Colin Richard. "Partition proteins of bacterial genomes." Thesis, University of Birmingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367278.

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5

O'Neill, Jason Charles Walker. "Structural studies on the B1 domain of protein L : biophysical affects of single site mutations, 3D-domain swapping, and computational redesign /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/4990.

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6

Rozell, Björn. "Immunohistochemical studies of the thioredoxin system." Göteborg : Dept. of Histology, University of Göteborg, 1987. http://catalog.hathitrust.org/api/volumes/oclc/17242526.html.

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7

Haas, R. Matthew. "Synthesis and characterization of phosphono-CheY from Thermotoga maritima /." Electronic version (PDF), 2007. http://dl.uncw.edu/etd/2007-1/haasr/rmatthewhaas.html.

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8

Château, Maarten de. "Functional, structural and evolutionary studies on a family of bacterial surface proteins." Lund : Dept. of Cell and Molecular Biology, Lund University, 1996. http://catalog.hathitrust.org/api/volumes/oclc/38947242.html.

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9

Gu, Hongdi. "The sequence determinants of folding for a small globular protein /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/9203.

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10

Agnew, Christopher R. J. "Structural studies of bacterial infection proteins." Thesis, University of Bristol, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.544420.

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11

Reeves, Adam J. "Signaling and interaction of the Bacillus subtilis physical stress pathway regulators of sigma B : a dissertation /." San Antonio : UTHSC, 2007. http://proquest.umi.com/pqdweb?did=1390290691&sid=1&Fmt=2&clientId=70986&RQT=309&VName=PQD.

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12

Sebastião, Isis [UNESP]. "Toxicidade e interação de proteínas Cry1 de Bacillus thuringiensis em Helicoverpa armigera (Hübner) (Lepidóptera: Noctuidae)." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/123869.

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Made available in DSpace on 2015-06-17T19:34:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-02-26. Added 1 bitstream(s) on 2015-06-18T12:49:23Z : No. of bitstreams: 1 000829428_20170301.pdf: 100482 bytes, checksum: 894af24aad4ca7d75f9898581c07f398 (MD5) Bitstreams deleted on 2017-03-03T11:01:31Z: 000829428_20170301.pdf,. Added 1 bitstream(s) on 2017-03-03T11:02:40Z : No. of bitstreams: 1 000829428.pdf: 275587 bytes, checksum: 79098a3390015f4449a4b64413d932a8 (MD5)<br>Estudos que visam a interação das proteínas Cry de Bacillus thuringiensis, a fim de encontrar combinações adequada
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13

Sebastião, Isis. "Toxicidade e interação de proteínas Cry1 de Bacillus thuringiensis em Helicoverpa armigera (Hübner) (Lepidóptera: Noctuidae) /." Jaboticabal, 2015. http://hdl.handle.net/11449/123869.

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Orientador: Manoel Victor Franco Lemos<br>Coorientador: Ricardo Antonio Polanczyk<br>Banca: Janete Apparecida Desidério<br>Banca: Camila Chiaradia Davolos<br>Resumo: Estudos que visam a interação das proteínas Cry de Bacillus thuringiensis, a fim de encontrar combinações adequadas para o desenvolvimento de plantas Bt são ferramentais fundamentais no controle de lepidópteros-praga. A lagarta H. armigera causa danos severos nas culturas agrícolas e sua introdução no Brasil levou a busca de formas de controle eficientes e nesse contexto B. thuringiensis pode ser um bom agente de controle. Diante
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14

Turner, Leah R. "Mutational analysis of XcpR and PilB of Pseudomonas aeruginosa and characterization of XcpR dimer formation /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/11500.

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15

Delucchi, Anthony Benjamin. "Bacterial expression of radio-labeled recombinant proteins for studying AHR signalling." Scholarly Commons, 2001. https://scholarlycommons.pacific.edu/uop_etds/550.

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The ligand activated transcription factor Aryl Hydrocarbon Receptor (AHR) forms a DNA binding heterodimer with the Aryl Hydrocarbon Nuclear Translocator (ARNT) in response to planar aromatic hydrocarbons. In addition to AHR and ARNT there are at least three other proteins involved in AHR signaling. These proteins are the co-chaperone p23, Ara-9 and two molecules of Heat Shock Protein-90 (HSP-90). This study documents the production of Ara-9 and C∆418 (an ARNT deletion construct) in a modified thioredoxin fusion system. These proteins were expressed in a system that allowed for removal from the
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16

Karginov, Fedor Vladimirovitch. "Modular functions of bacterial DEAD-box proteins." Diss., Connect to online resource, 2005. http://wwwlib.umi.com/dissertations/fullcit/3178327.

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17

Gagnon, Jean-Nicolas. "Molecular interactions of bacterial outer membrane proteins." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=81333.

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Transport of iron-siderophores and vitamin B12 across the outer membrane (OM) of Gram-negative bacteria requires energy from the proton motive force delivered by the TonB/ExbB/ExbD complex. TonB-dependent OM receptors such as FhuA, FepA, FecA and BtuB possess a Ton box: a conserved motif located proximal to their N-terminus that has been shown to interact with TonB. However, other sites on OM receptors have been proposed to participate in interactions with TonB. To identify novel sites of interactions with TonB, we selected TonB-binding peptides from a random library of peptides display
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18

Berks, Benjamin Charles. "Molecular characterisation of bacterial electron transport proteins." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302884.

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19

Bond, Peter J. "Simulation studies of bacterial outer membrane proteins." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419258.

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20

Trambaiolo, Daniel Marco. "Crystallographic studies of bacterial cell division proteins." Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611977.

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21

Robb, Kirsty A. "Towards structural dynamics of bacterial GntR proteins." Thesis, University of Strathclyde, 2015. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=26536.

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The GntR super-family of transcriptional regulators are ubiquitously distributed throughout the prokaryotic world. There are currently 231,015 sequences in the Pfam database pertaining to GntR proteins (PF000392) from over 17,000 bacterial species. The proteobacteria, firmicutes and actinobacetria account for 95% of all GntR sequences in the database. Yet despite their wide distribution, very few have been studied in depth. The general structure of GntR proteins is a highly homologous helix-turn-helix (HTH) domain linked to a C-terminal effector binding/oligomerisation (Eb/O domain) by a flexi
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22

Lynch, Anthony Simon. "Studies of bacterial DNA topoisomerases." Thesis, University of York, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329651.

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23

Wisedchaisri, Goragot. "Structural basis for transcription regulations in Mycobacterium tuberculosis by iron-dependent regulator and dormancy survival regulator /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/9269.

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24

Pernestig, Anna-Karin. "The study of the Escherichia coli BarA-UvrY two-component system and its ability to sense the environment /." Stockholm, 2002. http://diss.kib.ki.se/2003/91-7349-474-7.

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25

Fairhead, Michael James. "Construction of human/bacterial cytochrome P450 fusion proteins." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.408140.

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26

Chan, Christopher. "Characterisation of electron transport proteins of bacterial denitrification." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320269.

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27

Aittoniemi, Jussi Tapio. "ABC proteins : from bacterial structures to human disease." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547442.

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28

Fleetwood, Filippa. "Bacterial display systems for engineering of affinity proteins." Doctoral thesis, KTH, Proteinteknologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-156420.

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Directed evolution is a powerful method for engineering of specific affinity proteins such as antibodies and alternative scaffold proteins. For selections from combinatorial protein libraries, robust and high-throughput selection platforms are needed. An attractive technology for this purpose is cell surface display, offering many advantages, such as the quantitative isolation of high-affinity library members using flow-cytometric cell sorting. This thesis describes the development, evaluation and use of bacterial display technologies for the engineering of affinity proteins. Affinity proteins
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29

Cheesman, Myles Richard. "Spectroscopic studies of nickel ions in bacterial proteins." Thesis, University of East Anglia, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327824.

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30

Nagalingam, Anil. "Towards the total synthesis of bacterial immunity proteins." Thesis, University of Leeds, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427784.

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31

Zhao, Yue. "Synthetic probes for bacterial lipids and dimerizing proteins." Thesis, Boston College, 2015. http://hdl.handle.net/2345/bc-ir:104623.

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Thesis advisor: Eranthie Weerapana<br>This thesis includes two projects: “Bacteria-selective borono-peptides” and “A split ligand for lanthanide binding: facile evaluation of dimerizing proteins”. In both projects, de novo designed molecules were synthesized, optimized and incorporated into peptides. These synthetic molecular tools allow selective targeting of bacterial cell membranes and analyzing the dynamic associations of membrane-embedded proteins. 1. Bacteria-selective borono-peptides As the antibiotic resistance continues to grow, bacterial infection becomes one of the major threats to
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32

Marucci, Suzana Cristina [UNESP]. "Interação de proteínas Vip3A e Cry1la10 de Bacillus thuringiensis com atividade inseticida a lepidópteros-praga." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/123778.

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Made available in DSpace on 2015-06-17T19:33:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-02-06. Added 1 bitstream(s) on 2015-06-18T12:47:49Z : No. of bitstreams: 1 000829635_20160806.pdf: 54783 bytes, checksum: 1f71baca5b42308b10e653a6d3b40058 (MD5) Bitstreams deleted on 2016-08-08T11:55:58Z: 000829635_20160806.pdf,. Added 1 bitstream(s) on 2016-08-08T11:56:33Z : No. of bitstreams: 1 000829635.pdf: 1135736 bytes, checksum: 5f82225f1067c07c36424e25cc5c44f1 (MD5)<br>As proteínas Vip3Aa e Cry1Ia apresentam potencial no controle de lepidópteros-praga e surgem como alternativa prom
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33

Marucci, Suzana Cristina. "Interação de proteínas Vip3A e Cry1la10 de Bacillus thuringiensis com atividade inseticida a lepidópteros-praga /." Jaboticabal, 2015. http://hdl.handle.net/11449/123778.

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Orientador: Janete Apparecida Desidério<br>Banca: Odair Aparecido Fernandes<br>Banca: Agda Paula Facincani<br>Banca: Paula Cristina Brunini Crialesi Legori<br>Banca: Juliana Regina Rossi<br>Resumo: As proteínas Vip3Aa e Cry1Ia apresentam potencial no controle de lepidópteros-praga e surgem como alternativa promissora no manejo da resistência de pragas as proteínas Cry1A, que tem sido altamente utilizada na formulação de bioinseticidas comerciais à base de Bacillus thuringiensis (Bt) e em plantas transgênicas. Assim sendo, o presente trabalho teve como objetivo a clonagem e expressão das proteí
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34

Fladvad, Malin. "Structure and function in c-Myc and Grx4 : two key proteins involved in transcriptional activation and oxidative stress /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7357-007-9/.

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35

Lu, Tonghua. "Characterization and strain distribution of multicopy allelic variants of the M. fermentans membrane lipoprotein gene, p57." free to MU campus, to others for purchase, 1998. http://wwwlib.umi.com/cr/mo/fullcit?p9901259.

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36

Zhao, Lei. "Characterization of bacterial homing endonuclease I-Ssp6803I /." Thesis, Connect to this title online; UW restricted, 2008. http://hdl.handle.net/1773/9214.

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37

Rapp, Mikaela. "The Ins and Outs of Membrane Proteins : Topology Studies of Bacterial Membrane Proteins." Doctoral thesis, Stockholm : Department of Biochemistry and Biophysics, Stockholm University, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-1330.

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38

Bjertsjö, Rennermalm Anna. "Staphylococcal cell wall associated proteins : characteristics and host interactions /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-542-9/.

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39

Allred, Daniel B. "Electrochemical nanomoulding through proteins /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/9862.

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40

Panjikar, Santosh. "Crystallographic studies of bacterial single stranded DNA-binding proteins." [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=964154366.

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41

Seyadarabi, Arefeh. "Structure-function studies of bacterial proteins involved in infection." Thesis, Queen Mary, University of London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498763.

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42

Vickers, Mark F. "Characterization of bacterial and mammalian recombinant nucleoside transport proteins." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0009/NQ59688.pdf.

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43

Lou, Hubing. "Structural and functional studies of bacterial outer membrane proteins." Thesis, University of St Andrews, 2010. http://hdl.handle.net/10023/995.

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This thesis studies two particular bacterial outer membrane proteins called OmpC and Wzi, focusing on their expression, purification, crystallization and X-ray structure determination. A series of four naturally occurring OmpC mutants were isolated from a single patient with an E. coli infection of liver cysts. The isolated E. coli strains progressively exhibited increasing breadth of antibiotic resistance in which OmpC was predicted to take a partial role. We carried out an assay in which a strain of E. coli lacking OmpC was used to express the first (antibiotic sensitive) and the last (antib
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44

Vaziri, Hamidreza. "Structure and Function Studies of Bacterial Membrane Transport Proteins." Thesis, University of Leeds, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485751.

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Nucleoside transporters play key roles in the uptake of nucleosides for salvage pathways of nucleotide synthesis in many organisms. In mammals, they also influence physiological processes, such as cardiovascular activity, via regulation of extracellular adenosine concentrations, and are the route of uptake for many anticancer and antiviral drugs. Unfortunately, understanding their molecular mechanisms in humans is hampered by their low abundance in the membrane and difficulty of expression. To obviate these problems, in the present project, bacterial proteins from the Hydroxy/Aromatic Amino Ac
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45

Schneider, Sabine. "Structural and biochemical studies on novel bacterial haem-proteins." Thesis, University of Nottingham, 2007. http://eprints.nottingham.ac.uk/10334/.

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Haem proteins are functionally and structurally extremely diverse biomolecules and play a vital role in aerobic life. They perform a vast range of functions like transport of oxygen and electron transfer, gene regulation, redox-sensing and drug metabolism. This many-sidedness of haem-proteins is due to the extremely versatile chemical properties of the iron in the haem prosthetic group. Iron, or iron in the form of haem, plays a key role in many biological processes and it is an essential nutrient for the majority of living organisms. Despite being one of the most abundant chemical elements, i
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46

McKinley, Laura Ellen. "Neutron reflectivity studies of bacterial membranes, peptides and proteins." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28874.

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This thesis uses neutron and x-ray reflectivity to measure the interfacial structures of three molecular components associated with bacteria. Firstly, the way in which the membrane targeting sequence of a cell division protein interacts with monolayer models for the inner leaflet of the inner membrane of bacteria was measured at the air-water interface. Secondly, the influence of lipopolysaccharide on a monolayer model for the outer leaflet of the outer membrane of Gram-negative bacteria was measured at the air-water interface, as well as how this lipopolysaccharide interacts with an antimicro
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47

Vezzoli, A. "Analysis of bacterial proteins interfering with eukaryotic cell proliferation." Doctoral thesis, Università degli Studi di Milano, 2006. http://hdl.handle.net/2434/56617.

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Descriptions of a role of some bacterial pathogens in counteracting tumour progression in humans date back to the end of XIX century. Recently, it was reported that two members of the family of cupredoxins, azurin from P. aeruginosa and rusticyanin from A. ferrooxidans, are able to enter in and to induce apoptosis and/or cell cycle arrest in a number of different cancer cell-lines. The apoptotic effect mediated by azurin was confirmed also in vivo. One of the specific aims of this thesis was to assess whether the expression of cupredoxins in S. cerevisiae could recapitulate the effects observe
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48

Crane, Jennine Marie. "Characterization of two modes of interaction between the chaperone SecB and its binding partners." Free to MU Campus, others may purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p3144410.

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49

Landgraf, Dirk. "Quantifying Localizations and Dynamics in Single Bacterial Cells." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10612.

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Levels of macromolecules fluctuate both spatially and temporally in individual cells. Such heterogeneity could be exploited for bet hedging in uncertain environments, or be suppressed by negative feedback if perturbations are deleterious. For the master stress-response regulator in Escherichia coli, RpoS, both of these scenarios have been suggested. RpoS levels are also exceedingly low and controlled by the ClpXP protease, which reportedly displays extreme spatial heterogeneity. However, little is known quantitatively about RpoS dynamics. This is partly because no functional protein fusions ex
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50

Sun, Eileen Soomie. "Subfamily I Treponema pallidum repeat proteins : sequence variation and immunity /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/9305.

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