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Journal articles on the topic 'Bacteroides uniformis'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Nomura, Kei, Dai Ishikawa, Koki Okahara, et al. "P168 BACTEROIDETES SPECIES ARE USEFUL BIOMARKER OF CLINICAL ACTIVITY IN ULCERATIVE COLITIS." Inflammatory Bowel Diseases 26, Supplement_1 (2020): S39. http://dx.doi.org/10.1093/ibd/zaa010.100.

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Abstract Background We previously reported that there were 13 species of Bacteroidetes phylum with significantly higher or lower relative abundance in patients with ulcerative colitis (UC) than healthy individuals. In this study, we investigated the correlation between Bacteroidetes species components in fecal samples and clinical evaluations of UC. Method This study included participants above 20 years of age. Fecal samples were collected for microbial analysis from 54 patients who had active UC based on a Lichtiger’s clinical activity index (CAI) ≥ 4 or an endoscopic Mayo clinic score ≥1. DN

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2

Koo, Hyunmin, and Casey D. Morrow. "Bacteroidales-Specific Antimicrobial Genes Can Influence the Selection of the Dominant Fecal Strain of Bacteroides vulgatus and Bacteroides uniformis from the Gastrointestinal Tract Microbial Community." Life 14, no. 5 (2024): 555. http://dx.doi.org/10.3390/life14050555.

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Bacteroides vulgatus and Bacteroides uniformis are known to be abundant in the human fecal microbial community. Although these strains typically remain stable over time in humans, disruption of this microbial community following antibiotics resulted in the transient change to new strains suggesting that a complex, dynamic strain community exists in humans. To further study the selection of dominant fecal microbial strains from the gastrointestinal tract (GIT) community, we analyzed three longitudinal metagenomic sequencing data sets using BLAST+ to identify genes encoding Bacteroidales-specifi

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3

Guo, Hang, Leilei Yu, Fengwei Tian, et al. "Effects of Bacteroides-Based Microecologics against Antibiotic-Associated Diarrhea in Mice." Microorganisms 9, no. 12 (2021): 2492. http://dx.doi.org/10.3390/microorganisms9122492.

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Antibiotic-associated diarrhea (AAD) is a self-limiting disease mediated by antibiotic therapy. In clinical practice, several types of probiotics are used in treating AAD, but minimal research has been done on Bacteroides-based microecologics. Our aim was to evaluate the therapeutic effects of Bacteroidetes uniformis FGDLZ48B1, B. intestinalis FJSWX61K18, Bifidobacterium adolescentis FHNFQ48M5, and B. bifidum FGZ30MM3 and their mixture on AAD in mice. The lincomycin hydrochloride-induced AAD models were gavaged with a single strain or a probiotic mixture for a short period to assess the change

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4

Jin, Zhen, Zhifeng Fang, Zhangming Pei, et al. "A low molecular weight brown algae Laminaria japonica glycan modulation of gut microbiota and body weight in mice." Food & Function 12, no. 24 (2021): 12606–20. http://dx.doi.org/10.1039/d1fo03024h.

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Brown algae glycan from Laminaria japonica (LJNP) is a heterogeneous glycan composed of glucose and fucose, which drove Bacteroides vulgatus and Bacteroides uniformis to regulate amino acid metabolism and glycometabolism.

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Nomura, Kei, Dai Ishikawa, Koki Okahara, et al. "Bacteroidetes Species Are Correlated with Disease Activity in Ulcerative Colitis." Journal of Clinical Medicine 10, no. 8 (2021): 1749. http://dx.doi.org/10.3390/jcm10081749.

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Fecal microbiota transplantation following triple-antibiotic therapy (amoxicillin/fosfomycin/metronidazole) improves dysbiosis caused by reduced Bacteroidetes diversity in patients with ulcerative colitis (UC). We investigated the correlation between Bacteroidetes species abundance and UC activity. Fecal samples from 34 healthy controls and 52 patients with active UC (Lichtiger’s clinical activity index ≥5 or Mayo endoscopic subscore ≥1) were subjected to next-generation sequencing with HSP60 as a target in bacterial metagenome analysis. A multiplex gene expression assay using colonoscopy-harv

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6

Lan, Pham Thi Ngoc, Mitsuo Sakamoto, Shinji Sakata, and Yoshimi Benno. "Bacteroides barnesiae sp. nov., Bacteroides salanitronis sp. nov. and Bacteroides gallinarum sp. nov., isolated from chicken caecum." International Journal of Systematic and Evolutionary Microbiology 56, no. 12 (2006): 2853–59. http://dx.doi.org/10.1099/ijs.0.64517-0.

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Eight bacterial strains isolated from the caecum of chicken, BL2T, BL66, EG3, EG6, M27, BL78T, C35T and C43, were characterized by determining their phenotypic characteristics, cellular fatty acid profiles, menaquinone profiles and phylogenetic positions based on 16S rRNA gene sequence analysis. 16S rRNA gene sequence analysis showed that these isolates belonged to the genus Bacteroides. One group of five strains (BL2T, BL66, EG3, EG6 and M27) was related most closely to Bacteroides coprocola JCM 12979T, with approximately 93 % 16S rRNA gene sequence similarity, and to Bacteroides plebeius JCM

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Kitahara, Maki, Sayaka Tsuchida, Koh Kawasumi, et al. "Bacteroides chinchillae sp. nov. and Bacteroides rodentium sp. nov., isolated from chinchilla (Chinchilla lanigera) faeces." International Journal of Systematic and Evolutionary Microbiology 61, no. 4 (2011): 877–81. http://dx.doi.org/10.1099/ijs.0.024026-0.

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Gram-negative anaerobic rods were isolated from chinchilla (Chinchilla lanigera) faeces and three strains, ST170T, ST180 and ST28T, were investigated taxonomically. On the basis of phylogenetic analyses and specific phenotypic characteristics, the three strains belonged to the genus Bacteroides. Phylogenetic analysis of their 16S rRNA gene sequences revealed that strains ST170T and ST180 formed a single cluster and a distinct line of descent. Strain ST170T exhibited 99.7 % 16S rRNA gene sequence similarity with strain ST180 and 95.1, 94.6 and 94.4 % 16S rRNA gene sequence similarity with Bacte

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8

Sun, Yuelong, Mengjie Zhang, Dongdong Shi, Xiaofeng Dai, and Xiumei Li. "Effects of Designed Herbal Formula on Growth Performance, Blood Indices, Organ Traits, and Cecum Microbiology in Broilers." Veterinary Sciences 11, no. 3 (2024): 107. http://dx.doi.org/10.3390/vetsci11030107.

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The objective of this study was to investigate the effect of the designed herbal formula (DHF) on growth performance, blood indices, organ traits, and cecum microbiology in broilers. A total of 96 male broilers of 1 d were selected and randomly assigned to two groups with six replicates of eight broilers each. The control (CON) and the basal diet containing 1.0% DHF (Astragali radix, Atractylodes macrocephala Koidz., Isatis tinctoria Linnaeus, and Citri reticulatae pericarpium, 2:1:1:2) were fed separately. The experiment was conducted for 35 days. The results showed that the DHF diet increase

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9

Shi, Jiameng, Wangting Zhou, Guijie Chen, Wei Yi, Yi Sun, and Xiaoxiong Zeng. "The Utilization by Bacteroides spp. of a Purified Polysaccharide from Fuzhuan Brick Tea." Foods 13, no. 11 (2024): 1666. http://dx.doi.org/10.3390/foods13111666.

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In the present study, four Bacteroides species that could degrade Fuzhuan brick tea polysaccharide-3 (FBTPS-3) were isolated from human feces and identified to be Bacteroides ovatus, B. uniformis, B. fragilis and B. thetaiotaomicron. The four Bacteroides species showed growth on FBTPS-3 as the carbon source, and B. ovatus showed the best capability for utilizing FBTPS-3 among the four species since B. ovatus could utilize more FBTPS-3 during 24 h fermentation. Moreover, the four Bacteroides species could metabolize FBTPS-3 and promote the production of acetic, propionic and isovaleric acids. T

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10

Zar, Fred A., and Elizabeth J. Bond. "Infection with Clindamycin–Resistant Bacteroides uniformis." Chemotherapy 31, no. 1 (1985): 29–33. http://dx.doi.org/10.1159/000238310.

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11

Antón, Enrique, Conchi Fernández, and Jose Manuel Barragán. "Spontaneous spondylodiscitis caused by bacteroides uniformis." American Journal of Medicine 117, no. 4 (2004): 284–86. http://dx.doi.org/10.1016/j.amjmed.2004.03.023.

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12

Matos, José, Isabel Matos, Manuela Calha, et al. "Insights from Bacteroides Species in Children with Type 1 Diabetes." Microorganisms 9, no. 7 (2021): 1436. http://dx.doi.org/10.3390/microorganisms9071436.

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In our previous study the enrichment of the intestinal proteome of type 1 diabetes (T1D) children with Bacteroides proteins was observed, which led us to our current study that aimed to isolate and characterize Bacteroides species from fecal samples of T1D and control children. Repetitive sequence-based PCR (rep-PCR) was used for typing the isolated Bacteroides species. The antibiotic susceptibility and mucinolytic activity of the isolates was determined. The quantification of specific bacterial groups in the fecal samples was determined by qPCR. The ability to adhere and invade the human colo

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13

Aldridge, Kenneth E., Deborah Ashcraft, Karl Cambre, Carl L. Pierson, Stephen G. Jenkins, and Jon E. Rosenblatt. "Multicenter Survey of the Changing In Vitro Antimicrobial Susceptibilities of Clinical Isolates of Bacteroides fragilis Group, Prevotella, Fusobacterium, Porphyromonas, and PeptostreptococcusSpecies." Antimicrobial Agents and Chemotherapy 45, no. 4 (2001): 1238–43. http://dx.doi.org/10.1128/aac.45.4.1238-1243.2001.

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ABSTRACT In vitro surveys of antimicrobial resistance among clinically important anaerobes are an important source of information that can be used for clinical decisions in the choice of empiric antimicrobial therapy. This study surveyed the susceptibilities of 556 clinical anaerobic isolates from four large medical centers using a broth microdilution method. Piperacillin-tazobactam was the only antimicrobial agent to which all the isolates were susceptible. Similarly, imipenem, meropenem, and metronidazole were highly active (resistance, <0.5%), whereas the lowest susceptibility rates were

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14

Dai, Wei, Jiaxue Zhang, Lu Chen, et al. "Discovery of Bacteroides uniformis F18-22 as a Safe and Novel Probiotic Bacterium for the Treatment of Ulcerative Colitis from the Healthy Human Colon." International Journal of Molecular Sciences 24, no. 19 (2023): 14669. http://dx.doi.org/10.3390/ijms241914669.

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Previous studies have demonstrated that the intestinal abundance of Bacteroides uniformis is significantly higher in healthy controls than that in patients with ulcerative colitis (UC). However, what effect B. uniformis has on the development of UC has not been characterized. Here, we show for the first time that B. uniformis F18-22, an alginate-fermenting bacterium isolated from the healthy human colon, protects against dextran-sulfate-sodium (DSS)-induced UC in mice. Specifically, oral intake of B. uniformis F18-22 alleviated colon contraction, improved intestinal bleeding and attenuated muc

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15

Rabbia, V., G. De Palma, P. Bercik, et al. "A45 FIBER-FREE DIET REDUCES BACTEROIDES ABUNDANCE AND PREVENTS MUCUS DEGRADATION IN MICE COLONIZED WITH MICROBIOTA FROM PATIENTS WITH GENERALIZED ANXIETY DISORDER." Journal of the Canadian Association of Gastroenterology 6, Supplement_1 (2023): 25–26. http://dx.doi.org/10.1093/jcag/gwac036.045.

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Abstract Background Generalized anxiety disorder (GAD) is a debilitating condition with a lifetime prevalence of 4-7% worldwide. We have previously found that compared to healthy controls, GAD patients had lower reported fiber intake, increased gastrointestinal symptoms; and enrichment of Bacteroides genus as well as carbohydrate metabolism pathways (as determined by PICRUSt2, correlated to Bacteroides abundance). Bacteroides are known for its ability to degrade a wide variety of host polysaccharides, such as the intestinal mucus, which could lead to local and systemic inflammation. In this re

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16

Bokkenheuser, V. D., C. H. Shackleton, and J. Winter. "Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans." Biochemical Journal 248, no. 3 (1987): 953–56. http://dx.doi.org/10.1042/bj2480953.

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Rutin and quercitrin are hydrolysed to quercetin, and robinin is hydrolysed to kaempferol, by faecal flora from healthy subjects. The enzymes required for these hydrolyses, namely alpha-rhamnosidase and beta-galactosidase, were produced by some strains of Bacteroides distasonis; other strains, however, synthesized beta-glucosidase. The last-named enzyme was also elaborated by Bacteroides uniformis and Bacteroides ovatus. All the enzymes were produced constitutively. A cell-free extract of B. distasonis containing beta-glucosidase displayed an enzymic activity of 1 mumol/10 min per 10 mg of pro

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Brown, Rebecca L., Max L. Y. Larkinson, and Thomas B. Clarke. "Immunological design of commensal communities to treat intestinal infection and inflammation." PLOS Pathogens 17, no. 1 (2021): e1009191. http://dx.doi.org/10.1371/journal.ppat.1009191.

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The immunological impact of individual commensal species within the microbiota is poorly understood limiting the use of commensals to treat disease. Here, we systematically profile the immunological fingerprint of commensals from the major phyla in the human intestine (Actinobacteria, Bacteroidetes, Firmicutes and Proteobacteria) to reveal taxonomic patterns in immune activation and use this information to rationally design commensal communities to enhance antibacterial defenses and combat intestinal inflammation. We reveal that Bacteroidetes and Firmicutes have distinct effects on intestinal

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18

Aldridge, Kenneth E. "Antimicrobial susceptibility of relatively infrequent isolates of the Bacteroides fragilis group: Bacteroides uniformis, bacteroides caccae, and Bacteroides eggerthii." Current Therapeutic Research 54, no. 2 (1993): 208–13. http://dx.doi.org/10.1016/s0011-393x(05)80603-4.

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19

Gómez del Pulgar, Eva M., Alfonso Benítez-Páez, and Yolanda Sanz. "Safety Assessment of Bacteroides Uniformis CECT 7771, a Symbiont of the Gut Microbiota in Infants." Nutrients 12, no. 2 (2020): 551. http://dx.doi.org/10.3390/nu12020551.

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The formulation of next-generation probiotics requires competent preclinical studies to show their efficacy and safety status. This study aims to confirm the safety of the prolonged oral use of Bacteroides uniformis CECT 7771, a strain that protected against metabolic disorders and obesity in preclinical trials, in a sub-chronic 90 day trial in animals. The safety assessment was conducted in male and female Wistar rats (n = 50) administered increasing doses (108 CFU/day, 109 CFU/day, or 1010 CFU/day) of B. uniformis CECT 7771, 1010 CFU/day of B. longum ATCC 15707T, which complies with the qual

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20

Lee, Hye-Bin, Moon-Ho Do, Hyunjhung Jhun, et al. "Amelioration of Hepatic Steatosis in Mice through Bacteroides uniformis CBA7346-Mediated Regulation of High-Fat Diet-Induced Insulin Resistance and Lipogenesis." Nutrients 13, no. 9 (2021): 2989. http://dx.doi.org/10.3390/nu13092989.

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Dietary habits and gut microbiota play an essential role in non-alcoholic fatty liver disease (NAFLD) and related factors such as insulin resistance and de novo lipogenesis. In this study, we investigated the protective effects of Bacteroides uniformis CBA7346, isolated from the gut of healthy Koreans, on mice with high-fat diet (HFD)-induced NAFLD. Administration of B. uniformis CBA7346 reduced body and liver weight gain, serum alanine aminotransferase and aspartate aminotransferase levels, liver steatosis, and liver triglyceride levels in mice on an HFD; the strain also decreased homeostatic

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21

Romaní-Pérez, Marina, Inmaculada López-Almela, Clara Bullich-Vilarrubias, Zoran Evtoski, Alfonso Benítez-Páez, and Yolanda Sanz. "Bacteroides uniformis CECT 7771 requires adaptive immunity to improve glucose tolerance but not to prevent body weight gain in diet-induced obese mice." Microbiome 12, no. 1 (2024): 103. https://doi.org/10.1186/s40168-024-01810-3.

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<strong>Background: </strong>The metabolic disturbances of obesity can be mitigated by strategies modulating the gut microbiota. In this study, we sought to identify whether innate or adaptive immunity mediates the beneficial metabolic effects of the human intestinal bacterium<i>Bacteroides uniformis</i>CECT 7771 in obesity.<strong>Methods: </strong>We evaluated the effects of orally administered<i>B. uniformis</i>on energy homeostasis, intestinal immunity, hormone levels, and gut microbiota in wild-type and<i>Rag1</i>-deficient mice with diet-induced obesity. We also assessed whether<i>B. uni

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Zhu, Xue-Xue, Chen-Yang Zhao, Xin-Yu Meng, et al. "Bacteroides uniformis Ameliorates Carbohydrate and Lipid Metabolism Disorders in Diabetic Mice by Regulating Bile Acid Metabolism via the Gut–Liver Axis." Pharmaceuticals 17, no. 8 (2024): 1015. http://dx.doi.org/10.3390/ph17081015.

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Background: Type 2 diabetes mellitus (T2DM) is a metabolic syndrome characterized by chronic inflammation, insulin resistance, and islet cell damage. The prevention of T2DM and its associated complications is an urgent public health issue that affects hundreds of millions of people globally. Numerous studies suggest that disturbances in gut metabolites are important driving forces for the pathogenesis of diabetes. However, the functions and mechanisms of action of most commensal bacteria in T2DM remain largely unknown. Methods: The quantification of bile acids (BAs) in fecal samples was perfor

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Lee, Dong Ho, Mijin Seol, Yu Ra Lee, et al. "Difference of colorectal cancer microbial community by metagenomics and culture-based methods." Journal of Clinical Oncology 37, no. 4_suppl (2019): 489. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.489.

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489 Background: Dysbiosis of intestinal microbiota is promoting the development of colorectal cancer (CRC). We confirmed the intestinal microbiota composition from fecal sample of Korean CRC patients. Metagenomic analysis was performed and we isolated single microbes through culture-based method. Methods: CRC fecal samples were collected from 12 individuals. Metagenome Sequencing was based on the 16S rRNA gene amplicon on the Illumina MiSeq platform. The bacteria strains were subcultivated on the agar plate medium in aerobic and anaerobic and further identified by using the 16s rRNA gene seque

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Brook, Itzhak, and Edith H. Frazier. "Recovery of Bacteroides fragilis group from clinical specimens following antimicrobial therapy." Canadian Journal of Microbiology 38, no. 3 (1992): 226–29. http://dx.doi.org/10.1139/m92-038.

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Over a period of 14 years (1973–1987), 3165 specimens submitted to the microbiology laboratory demonstrated the recovery of anaerobic bacteria. A total of 988 Bacteroides fragilis group isolates were recovered (0.3 isolates per specimen). Bacteroides fragilis accounted for 62% of the total of all B. fragilis group isolates, Bacteroides thetaiotaomicron for 15%, Bacteroides vulgatus for 8%, Bacteroides ovatus for 7%, Bacteroides distasonis for 6%, and Bacteroides uniformis for 2%. Of the 988 B. fragilis group isolates, 310 (31%) were recovered after the administration of antimicrobial therapy,

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Kabiri, Leila, Absar Alum, Channah Rock, Jean E. McLain, and Morteza Abbaszadegan. "Isolation of Bacteroides from fish and human fecal samples for identification of unique molecular markers." Canadian Journal of Microbiology 59, no. 12 (2013): 771–77. http://dx.doi.org/10.1139/cjm-2013-0518.

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Bacteroides molecular markers have been used to identify human fecal contamination in natural waters, but recent work in our laboratory confirmed cross-amplification of several human-specific Bacteroides spp. assays with fecal DNA from fish. For identification of unique molecular markers, Bacteroides from human (n = 4) and fish (n = 7) fecal samples were cultured and their identities were further confirmed using Rapid ID 32A API strips. The 16S rDNA from multiple isolates from each sample was PCR amplified, cloned, and sequenced to identify unique markers for development of more stringent huma

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Ng, Ho-Yu, Yunshi Liao, Ruiqi Zhang, et al. "The Predictive Value of Gut Microbiota Composition for Sustained Immunogenicity following Two Doses of CoronaVac." International Journal of Molecular Sciences 25, no. 5 (2024): 2583. http://dx.doi.org/10.3390/ijms25052583.

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CoronaVac immunogenicity decreases with time, and we aimed to investigate whether gut microbiota associate with longer-term immunogenicity of CoronaVac. This was a prospective cohort study recruiting two-dose CoronaVac recipients from three centres in Hong Kong. We collected blood samples at baseline and day 180 after the first dose and used chemiluminescence immunoassay to test for neutralizing antibodies (NAbs) against the receptor-binding domain (RBD) of wild-type SARS-CoV-2 virus. We performed shotgun metagenomic sequencing performed on baseline stool samples. The primary outcome was the N

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Watanabe, Yohei, Fumiko Nagai, Masami Morotomi, Hiroshi Sakon, and Ryuichiro Tanaka. "Bacteroides clarus sp. nov., Bacteroides fluxus sp. nov. and Bacteroides oleiciplenus sp. nov., isolated from human faeces." International Journal of Systematic and Evolutionary Microbiology 60, no. 8 (2010): 1864–69. http://dx.doi.org/10.1099/ijs.0.015107-0.

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Three Gram-stain-negative, obligately anaerobic, non-spore-forming, rod-shaped bacteria (strains YIT 12056T, YIT 12057T and YIT 12058T) were isolated from human faeces. These strains were characterized by phylogenetic analyses based on 16S rRNA gene sequence and phenotypic tests. 16S rRNA gene sequence analyses revealed that strains YIT 12056T, YIT 12057T and YIT 12058T were most closely related to the type strains of Bacteroides gallinarum, Bacteroides uniformis and Bacteroides intestinalis with approximate similarity values of 96.6, 95.0 and 96.7 %, respectively. The DNA G+C contents of the

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Bogdan, Maja, Vlasta Zujić Atalić, Ivan Hećimović, and Dubravka Vuković. "Brain abscess due to Aggregatibacter aphrophilus and Bacteroides uniformis." Acta Medica Academica 44, no. 2 (2015): 181. http://dx.doi.org/10.5644/ama2006-124.144.

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<p><strong>Objective</strong>. The aim of this report was to describe the occurrence of a bacterial brain abscess in a healthy individual, without any predisposing condition. <strong>Case report</strong>. A thirteen-year old boy was admitted to the Department of Neurosurgery after the onset of vomiting, headache and dizziness. A neurological deficit was detected during the physical examination so urgent magnetic resonance imaging of the brain was performed, revealing an intrahemispheric, right positioned solitary expansive mass with ring enhancement. Purulent mate

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Hedžet, Stina, Maja Rupnik, and Tomaž Accetto. "Novel Siphoviridae Bacteriophages Infecting Bacteroides uniformis Contain Diversity Generating Retroelement." Microorganisms 9, no. 5 (2021): 892. http://dx.doi.org/10.3390/microorganisms9050892.

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Intestinal phages are abundant and important components of gut microbiota, yet the isolated and characterized representatives that infect abundant gut bacteria are sparse. Here we describe the isolation of human intestinal phages infecting Bacteroidesuniformis. Bacteroides is one of the most common bacterial groups in the global human gut microbiota; however, to date not many Bacteroides specific phages are known. Phages isolated in this study belong to a novel viral genus, Bacuni, within the Siphoviridae family. Their genomes encode diversity-generating retroelements (DGR), which were shown i

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Citron, Diane M., and Maria D. Appleman. "Comparative In Vitro Activities of ABT-773 against 362 Clinical Isolates of Anaerobic Bacteria." Antimicrobial Agents and Chemotherapy 45, no. 1 (2001): 345–48. http://dx.doi.org/10.1128/aac.45.1.345-348.2001.

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ABSTRACT The activity of ABT-773, a novel ketolide antibiotic, against clinical isolates of anaerobic bacteria was determined and compared to the activities of other antimicrobial agents. MICs at which 90% of isolates were inhibited (MIC90s) were ≤0.06 μg/ml for Actinomyces spp., Clostridium perfringens, Peptostreptococcus spp.,Propionibacterium spp., and Porphyromonasspp. The MIC50s and MIC90s were ≤0.06 and >32 μg/ml, respectively, for Eubacterium spp.,Lactobacillus spp., Clostridium difficile, and Clostridium ramosum. The MIC90 for Bilophila wadsworthia,Bacteroides ureolyticus, and Campy

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Kamiya, Shigeru. "LIVE BIOTHERAPEUTIC PRODUCT AND CANCER IMMUNOTHERAPY." Romanian Archives of Microbiology and Immunology 82, no. 3 (2023): 210–13. http://dx.doi.org/10.54044/rami.2023.03.07.

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Probiotics are defined as ‘’live microorganisms that, when administered in adequate amounts, confer a health benefit on the host’’ [1]. Compared to conventional probiotics, novel beneficial effects on human health by a wide range of microbial probiotics have been reported, and such probiotics are called as next-generation probiotics (NGP), which are defined as ‘’new beneficial probiotics different from classical probiotics of Lactobacillus and Bifidobacterium’’ [2]. NGPs include various bacterial species such as Faecalibacterium prausnitzii, Akkermansia muciniphila, Bacteroides fragilis/Bacter

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Reges, Bianca Mara, Francisca Andréa da Silva Oliveira, Thatyane Vidal Fonteles, and Sueli Rodrigues. "Changes in Human Colonic Microbiota Promoted by Synbiotic Açai Juice Composed of Gluco-Oligosaccharides, Dextran, and Bifidobacterium breve NRRL B-41408." Foods 13, no. 24 (2024): 4121. https://doi.org/10.3390/foods13244121.

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The present study evaluates the effects of açai juice containing gluco-oligosaccharides and dextran, fermented by Bifidobacterium breve NRRL B-41408 (synbiotic juice), on the human fecal microbiota. The juice is subjected to simulated digestion and fecal fermentation after production and 42 days of refrigerated storage. High throughput 16S rRNA sequencing and HPLC are used to identify the bacterial cells and metabolites. The results show that the viability of B. breve is stable during the refrigerated storage, indicating that the metabolism is maintained even under low temperatures and pH. Fur

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Liu, C., X. Zhuang, S. Zhan, et al. "P149 Bacteroides uniformis ameliorates pro-inflammatory diet-exacerbated colitis by targeting endoplasmic reticulum stress-mediated ferroptosis." Journal of Crohn's and Colitis 18, Supplement_1 (2024): i452. http://dx.doi.org/10.1093/ecco-jcc/jjad212.0279.

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Abstract Background Pro-inflammatory diet is positively associated with the risk and progression of inflammatory bowel diseases. Recently, ferroptosis was observed in patients with dietary pattern-associated colitis. However, the mechanisms underlying the effects of a pro-inflammatory diet and whether it mediates ferroptosis are unknown. This study aimed to clarify the mechanisms of pro-inflammatory diet in colitis. Methods Mice were fed a dietary inflammatory index-based pro-inflammatory diet for 12 weeks. Subsequently, colitis was chemically induced using 2.5% dextran sulfate sodium with or

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Tsuneko Ono. "Cloning and expression of the Bacteroides fragilis YCH46 neuraminidase gene in Eschirichia coli and Bacteroides uniformis." FEMS Microbiology Letters 121, no. 2 (1994): 153–58. http://dx.doi.org/10.1016/0378-1097(94)90120-1.

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Gupta, Anamika, Hera Vlamakis, Nadja Shoemaker, and Abigail A. Salyers. "A New Bacteroides Conjugative Transposon That Carries an ermB Gene." Applied and Environmental Microbiology 69, no. 11 (2003): 6455–63. http://dx.doi.org/10.1128/aem.69.11.6455-6463.2003.

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ABSTRACT The erythromycin resistance gene ermB has been found in a variety of gram-positive bacteria. This gene has also been found in Bacteroides species but only in six recently isolated strains; thus, the gene seems to have entered this genus only recently. One of the six Bacteroides ermB-containing isolates, WH207, could transfer ermB to Bacteroides thetaiotaomicron strain BT4001 by conjugation. WH207 was identified as a Bacteroides uniformis strain based on the sequence of its 16S rRNA gene. Results of pulsed-field gel electrophoresis experiments demonstrated that the transferring element

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Shoemaker, N. B., and A. A. Salyers. "Tetracycline-dependent appearance of plasmidlike forms in Bacteroides uniformis 0061 mediated by conjugal Bacteroides tetracycline resistance elements." Journal of Bacteriology 170, no. 4 (1988): 1651–57. http://dx.doi.org/10.1128/jb.170.4.1651-1657.1988.

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Hedberg, M., L. Lindqvist, T. Bergman, and C. E. Nord. "Purification and characterization of a new beta-lactamase from Bacteroides uniformis." Antimicrobial Agents and Chemotherapy 39, no. 7 (1995): 1458–61. http://dx.doi.org/10.1128/aac.39.7.1458.

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Kaçar Mutlutürk, Ülger, Betül Çiçek, and Gizem Cengiz. "The Effect of the Ideal Food Pyramid on Gut Microbiota in Rheumatoid Arthritis Patients." Life 15, no. 3 (2025): 463. https://doi.org/10.3390/life15030463.

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Background: The gut microbiota composition of rheumatoid arthritis (RA) patients differs from healthy people, and diet is among the powerful environmental determinants that can alter the microbiota. The purpose of this clinical research was to identify the effect of the Ideal Food Pyramid on gut microbiota in RA, as well as its impact on disease activity, biochemical findings and anthropometric measurements. Methods: Thirty patients diagnosed with RA that met the inclusion criteria were randomized into diet and control groups and followed for 12 weeks. The gut microbiota composition was indica

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Hong, Pei-Ying, Jer-Horng Wu, and Wen-Tso Liu. "Relative Abundance of Bacteroides spp. in Stools and Wastewaters as Determined by Hierarchical Oligonucleotide Primer Extension." Applied and Environmental Microbiology 74, no. 9 (2008): 2882–93. http://dx.doi.org/10.1128/aem.02568-07.

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ABSTRACT A molecular method, termed hierarchical oligonucleotide primer extension (HOPE), was used to determine the relative abundances of predominant Bacteroides spp. present in fecal microbiota and wastewaters. For this analysis, genomic DNA in feces of healthy human adults, bovines, and swine and in wastewaters was extracted and total bacterial 16S rRNA genes were PCR amplified and used as the DNA templates for HOPE. Nineteen oligonucleotide primers were designed to detect 14 Bacteroides spp. at different hierarchical levels (domain, order, cluster, and species) and were arranged into and u

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Goldstein, Ellie J. C., Diane M. Citron, Yumi A. Warren, Kerin L. Tyrrell, C. Vreni Merriam, and Helen Fernandez. "In Vitro Activity of Moxifloxacin against 923 Anaerobes Isolated from Human Intra-Abdominal Infections." Antimicrobial Agents and Chemotherapy 50, no. 1 (2006): 148–55. http://dx.doi.org/10.1128/aac.50.1.148-155.2006.

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ABSTRACT The in vitro activity of moxifloxacin against 923 recent anaerobic isolates obtained from pretreatment cultures in patients with complicated intra-abdominal infections was studied using the CLSI M11-A-6 agar dilution method. Moxifloxacin was active against 87% (96 of 110) Bacteroides fragilis strains at ≤1 μg/ml and 87% (79 of 90) B. thetaiotaomicron strains at ≤2 μg/ml. Species variation was seen, with B. uniformis, B. vulgatus, Clostridium clostridioforme, and C. symbiosum being least susceptible and accounting for most of the resistant isolates; excluding the aforementioned four re

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Oh, Herin, Nagwa El Amin, Todd Davies, Peter C. Appelbaum, and Charlotta Edlund. "gyrA Mutations Associated with Quinolone Resistance in Bacteroides fragilis Group Strains." Antimicrobial Agents and Chemotherapy 45, no. 7 (2001): 1977–81. http://dx.doi.org/10.1128/aac.45.7.1977-1981.2001.

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ABSTRACT Mutations in the gyrA gene contribute considerably to quinolone resistance in Escherichia coli. Mechanisms for quinolone resistance in anaerobic bacteria are less well studied. TheBacteroides fragilis group are the anaerobic organisms most frequently isolated from patients with bacteremia and intraabdominal infections. Forty-four clinafloxacin-resistant and-susceptible fecal and clinical isolates of the B. fragilis group (eightBacteroides fragilis, three Bacteroides ovatus, five Bacteroides thetaiotaomicron, six Bacteroides uniformis, and 22 Bacteroides vulgatus) and six ATCC strains

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Wu, *Lawrence Shih Hsin, Ming Chyi Huang, and Shi Chun Meng. "ASSOCIATION BETWEEN GUT MICROBIOME AND DRINKING TYPES OF ALCOHOL USE DISORDER." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i299—i300. https://doi.org/10.1093/ijnp/pyae059.532.

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Abstract Background Alcohol use disorder (AUD) presents as a diverse condition, with clinical characteristics linked to treatment effectiveness varying among individuals. For example, distinct patterns of drinking exhibit distinct reactions to Naltrexone therapy. Individuals classified as reward drinkers tend to display a higher likelihood of positive response to Naltrexone treatment. Utilizing the gut-brain axis mechanism as a foundation, we explore disparities in gut microbiome profiles across various drinking patterns. Methods So far, a total of 36 patients diagnosed with AUD were included

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Amini Khiabani, Siamak, Setareh Haghighat, Hamid Tayebi Khosroshahi, Mohammad Asgharzadeh, and Hossein Samadi Kafil. "Diversity of Bacteroidaceae family in gut microbiota of patients with chronic kidney disease and end stage renal disease." Health Promotion Perspectives 13, no. 3 (2023): 237–42. http://dx.doi.org/10.34172/hpp.2023.29.

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Background: Human intestine microbiota are known to be directly and indirectly altered during some diseases such as kidney complications. Bacteroides is considered as the main and the most abundant phylum among human gut microbiota, which has been classified as enterotype 1. This study aimed to assess the abundance of Bacteroides spp. in fecal flora of end-stage renal disease (ESRD) and chronic kidney disease (CKD) patients and compare it with the Bacteroides composition among fecal flora of healthy individual. Methods: Fresh fecal samples were collected from 20 CKD/ESRD patients and 20 health

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Martinez-Suarez, J. V., F. Baquero, M. Reig, and J. C. Perez-Diaz. "Transferable plasmid-linked chloramphenicol acetyltransferase conferring high-level resistance in Bacteroides uniformis." Antimicrobial Agents and Chemotherapy 28, no. 1 (1985): 113–17. http://dx.doi.org/10.1128/aac.28.1.113.

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Ma, Mingfeng, Min Quan, Jiaxue Zhang, et al. "In Vitro Fermentation of Polysaccharide from Edible Alga Enteromorpha clathrata by the Gut Microbiota of Patients with Ulcerative Colitis." Nutrients 15, no. 19 (2023): 4122. http://dx.doi.org/10.3390/nu15194122.

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Dietary intake of the sulfated polysaccharide from edible alga E. clathrata (ECP) has recently been illustrated to attenuate ulcerative colitis (UC) by targeting gut dysbiosis in mice. However, ECP is not easily absorbed in the gut and, as a potential candidate for next-generation prebiotics development, how it is fermented by human gut microbiota has not been characterized. Here, using in vitro anaerobic fermentation and 16S high-throughput sequencing, we illustrate for the first time the detailed fermentation characteristics of ECP by the gut microbiota of nine UC patients. Our results indic

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Kollarcikova, Miloslava, Marcela Faldynova, Jitka Matiasovicova, et al. "Different Bacteroides Species Colonise Human and Chicken Intestinal Tract." Microorganisms 8, no. 10 (2020): 1483. http://dx.doi.org/10.3390/microorganisms8101483.

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Bacteroidaceae are common gut microbiota members in all warm-blooded animals. However, if Bacteroidaceae are to be used as probiotics, the species selected for different hosts should reflect the natural distribution. In this study, we therefore evaluated host adaptation of bacterial species belonging to the family Bacteroidaceae. B. dorei, B. uniformis, B. xylanisolvens, B. ovatus, B. clarus, B. thetaiotaomicron and B. vulgatus represented human-adapted species while B. gallinaceum, B. caecigallinarum, B. mediterraneensis, B. caecicola, M. massiliensis, B. plebeius and B. coprocola were common

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Shoemaker, N. B., and A. A. Salyers. "A cryptic 65-kilobase-pair transposonlike element isolated from Bacteroides uniformis has homology with Bacteroides conjugal tetracycline resistance elements." Journal of Bacteriology 172, no. 4 (1990): 1694–702. http://dx.doi.org/10.1128/jb.172.4.1694-1702.1990.

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López-Almela, Inmaculada, Marina Romaní-Pérez, Clara Bullich-Vilarrubias, et al. "Bacteroides uniformis combined with fiber amplifies metabolic and immune benefits in obese mice." Gut Microbes 13, no. 1 (2021): 1865706. http://dx.doi.org/10.1080/19490976.2020.1865706.

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Singh, Ravindra Pal, Raksha Thakur та Gulshan Kumar. "Human gut Bacteroides uniformis utilizes mixed linked β-glucans via an alternative strategy". Bioactive Carbohydrates and Dietary Fibre 26 (листопад 2021): 100282. http://dx.doi.org/10.1016/j.bcdf.2021.100282.

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McKarns, Susan C., Patrick G. Miller, Craig Franklin, Aaron C. Ericsson, and Michael B. Bonn. "TNF receptor type 2 (TNFR2) in the maintenance of gut microbiota and autoimmune disease susceptibility." Journal of Immunology 196, no. 1_Supplement (2016): 118.10. http://dx.doi.org/10.4049/jimmunol.196.supp.118.10.

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Abstract Tumor necrosis factor (TNF) antagonism is therapeutic for some inflammatory autoimmune disorders such as Crohn’s disease and rheumatoid arthritis. However, TNF blockade inexplicably exacerbates CNS autoimmunity, including multiple sclerosis. We now demonstrate that selective TNFR2 deficiency augments spontaneous autoimmunity in female, but not male, myelin oligodendrocyte glycoprotein (MOG)–specific 2D2 TCR transgenic mice. Disease in TNFR2−/− 2D2 mice correlates with CNS lymphocyte infiltration and increased myelin oligodendrocyte glycoprotein–induced IL-17, IFN-γ, and IgG2b producti

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