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Dissertations / Theses on the topic 'Balance inflammatoire'

Author: Grafiati

Published: 21 December 2024

Last updated: 31 July 2025

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1

Motta, Jean-Paul. "Rôle de la balance protéolytique dans l'immunité de la muqueuse intestinale." Toulouse 3, 2012. http://thesesups.ups-tlse.fr/1883/.

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Le traitement des patients atteints de Maladies Inflammatoires Chroniques de l'Intestin (MICI) représente un enjeu d'avenir. La réponse inflammatoire dans l'intestin impliquent la libération de plusieurs médiateurs, comme les protéases. Dans cette thèse, nous avons montré qu'il y avait un déséquilibre entre ces protéases et leurs inhibiteurs au cours des MICI. D'une part, les tissus coliques de ces patients libéraient davantage d'activité protéolytique en comparaison aux tissus sains. D'autre part, les patients atteints de MICI exprimaient dans la muqueuse intestinale une quantité réduite d'AR

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2

Tournadre, Anne. "Immunité innée, balance th1/th17 et précurseurs musculaires dans les myopathies inflammatoires." Phd thesis, Université Claude Bernard - Lyon I, 2010. http://tel.archives-ouvertes.fr/tel-00715926.

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Cette thèse, consacrée aux myopathies inflammatoires, démontre le rôle dans les maladies auto-immunes des Toll-like récepteurs (TLRs), véritable passerelle entre immunité innée et adaptative, et plus spécifiquement dans le muscle, le rôle fondamental de la cellule musculaire elle-même. Après une présentation globale des myopathies inflammatoires et des différents aspects immunopathologiques, la réponse immunitaire adaptative est abordée en rapportant notamment dans le muscle des myopathies inflammatoires une accumulation de cellules dendritiques matures, et la présence des lymphocytes Th1 et T

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3

Lorvellec, Marie. "Dialogue entre le complément C1 et l'alarmine HMGB1 dans l'inflammation." Electronic Thesis or Diss., Université Grenoble Alpes, 2024. http://www.theses.fr/2024GRALV033.

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La protéase C1s est un élément central dans l’initiation de la voie classique du système du complément. Elle était auparavant considérée comme ciblant exclusivement les protéines C2 et C4 dans cette cascade protéolytique. Des découvertes récentes ont cependant mis en lumière la présence de C1s libre constitutivement active dans certaines pathologies, suggérant un rôle plus large de cette protéase au-delà de l'activation du complément. Parmi les cibles non-canoniques identifiées de C1s figure la protéine HMGB1, initialement décrite comme une protéine nucléaire impliquéedans la condensation de l

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4

Gormley, Sheena Mary Catherine. "Plasma and urinary cytokine balance and renal function during cardiac surgery." Thesis, Queen's University Belfast, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326410.

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5

McLean, Gavin W. "An investigation into the balance of pro- and anti-inflammatory cytokines in cardiac surgery and hip fracture surgery." Thesis, Queen's University Belfast, 2017. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.727756.

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The aim of this study was to investigate the balance of pro- and anti-inflammatory cytokines in patients undergoing cardiac and hip fracture surgery in relation to the development of postoperative acute kidney injury (AKI). 400 patients undergoing elective cardiac surgery and 237 patients undergoing emergency hip fracture surgery were recruited. For each patient blood and urine samples were analysed preoperatively and postoperatively to determine how cytokine balance alters in those patients who develop postoperative AKI. In both patients groups, the balance of pro- and anti-inflammatory cytok

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6

Cabrera, Rojas Natalia. "Efficacité et tolérance des agents biologiques dans les rhumatismes inflammatoires à début juvénile dans les essais cliniques randomisés et les études observationnelles." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE1191/document.

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Les rhumatismes inflammatoires juvéniles sont des maladies chroniques débutant avant l’âge de 16 ans. Comprennent des pathologies classées dans un continuum, allant de la dérégulation de l’immunité innée à la dérégulation de l‘immunité adaptative. L’arthrite juvénile idiopathique (AJI) reste la plus fréquemment diagnostiqué. Les options thérapeutiques se sont élargies à partir des années 2000 avec le développement des thérapies ciblées, les biothérapies, associés aux traitements standard utilisés en rhumatologie pédiatrique (ex : anti-inflammatoires non stéroïdiens, corticostéroïdes, méthotrex

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7

Henno, Priscilla. "Dysfonctions vasculaire et bronchique dans deux modèles de bronchopathies chroniques inflammatoires chez l’homme : tabagisme et mucoviscidose. Voies de l’endothéline-1 et de la balance NOS/arginases." Thesis, Paris Est, 2010. http://www.theses.fr/2010PEST0043.

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L'endothélium artériel pulmonaire joue un rôle déterminant dans la régulation du tonus vasomoteur en libérant des substances vasodilatatrices et vasoconstrictrices. Toute perturbation des fonctions endothéliales entraîne une perte de l'équilibre physiologique très finement régulé entre réponse vasoconstrictrice et vasodilatatrice, avec perte conjointe du contrôle de la prolifération des cellules musculaires lisses vasculaires et de l'effet antiagrégant plaquettaire. Ces modifications conduisent à un remodelage du lit vasculaire pulmonaire avec une augmentation des résistances vasculaires parfo

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8

Costa, Fernando Oliveira. "Efeito agudo da galantamina em parâmetros hemodinâmicos e autonômicos em portadores da síndrome metabólica: estudo clínico prospectivo randomizado." Universidade Nove de Julho, 2014. http://bibliotecadigital.uninove.br/handle/tede/1152.

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Submitted by Nadir Basilio (nadirsb@uninove.br) on 2015-07-27T14:45:59Z No. of bitstreams: 1 Fernando Oliveira Costa.pdf: 1199928 bytes, checksum: f721f323b7b101614061ea44e7dd6cb3 (MD5)<br>Made available in DSpace on 2015-07-27T14:45:59Z (GMT). No. of bitstreams: 1 Fernando Oliveira Costa.pdf: 1199928 bytes, checksum: f721f323b7b101614061ea44e7dd6cb3 (MD5) Previous issue date: 2014-02-21<br>The metabolic syndrome (MetS) consists of a combination of conditions that tend to cluster together, and increase the risk of type 2 diabetes and cardiovascular disease. The components of the metabolic sy

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9

Werncke, Daíse. "Relação entre restrição nutricional e acidose ruminal com as alterações na produção e composição do leite." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/163326.

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O estudo consistiu de dois experimentos com o objetivo de avaliar os efeitos da acidose ruminal e restrição nutricional na ocorrência de processos inflamatórios nos animais e relacionar com as alterações na produção e composição do leite. Foram utilizadas doze vacas Holandês e Mestiças Holandês Jersey. Experimento 1: Na fase de adaptação, os animais receberam uma dieta formulada para atender 100% das necessidades nutricionais de energia e proteína. Na indução foi administrada uma dieta com restrição de 50% das necessidades em energia e proteína. Na recuperação os animais receberam uma das três

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10

Bäck, Christer Matthias [Verfasser], Uwe [Akademischer Betreuer] Conrath, and Frank [Akademischer Betreuer] Tacke. "MCP-1 dependent balance of inflammatory pathways and interplay of immune cells in the liver during injury, fibrosis and injury regression : unterschiedliche MCP-1-abhängige Entzündungsmechanismen und Interaktionen von Immunzellen in der Leber / Christer Matthias Bäck ; Uwe Conrath, Frank Tacke." Aachen : Universitätsbibliothek der RWTH Aachen, 2015. http://d-nb.info/1129787419/34.

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11

Seeboth, Julie. "Impact des trichothécènes sur l'immunité des muqueuses et utilisation de Lactobacillus sobrius comme moyen de lutte microbiologique contre ces mycotoxines." Thesis, Toulouse, INPT, 2013. http://www.theses.fr/2013INPT0067/document.

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Les mycotoxines sont des métabolites secondaires des moisissures qui peuvent naturellement contaminer de nombreux supports (céréales, fruits, papiers peints, compost). Dans ces travaux de thèse, nous avons focalisé notre intérêt sur deux mycotoxines produites principalement par les champignons du genre Fusarium, appartenant toutes deux au même groupe des trichothécènes, le déoxynivalénol (DON) et la toxine T-2 (T-2). Les objectifs de cette thèse ont été de déterminer les effets de ces deux toxines sur la mise en place des réponses immunitaires au sein de la muqueuse respiratoire et intestinale

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12

Ezequiel, Catarina Alexandra Barbosa. "Balance between pro-inflammatory/anti-inflammatory indicators of SOD1G93A microglia in steady conditions and modification by immunomodulation." Master's thesis, 2017. http://hdl.handle.net/10451/34248.

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Tese de mestrado, Ciências Biofarmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2017<br>Amyotrophic Lateral Sclerosis (ALS) is the third most common neurodegenerative disease, mostly sporadic, with limited identified targets, biomarkers and therapeutic options. The most widely used animal model and experimental cellular models to study ALS pathological mechanisms are based on mutations in the anti-oxidant protein SOD1, particularly that of G93A. ALS affects mainly motor neurons, but it is widely accepted that immune unbalance plays a crucial role in the ALS disease, and microglial

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13

Min-Hua, Wang, and 王敏華. "Effect of Systemic Inflammatory Response on Energy Expenditure and Nitrogen Balance of Surgical Critically Ill Patients." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/15580155702351617746.

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碩士<br>國立陽明大學<br>臨床護理研究所<br>91<br>The purpose of this study was to examine the effect of systemic inflammatory response on energy expenditure and nitrogen balance of surgical critically ill patients. In respect to the existence of systemic inflammatory response syndrome (SIRS) or infection, fifty-six patients were classified into three groups: Non-SIRS, Nonseptic SIRS and SEPSIS. The resting energy expenditure (REE) was determined by indirect calorimetry. On the day of the energy measurement, the 24-hour urine samples were collected and the dietary intake was recorded. Nonseptic SIRS and SEPSIS

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14

Bottu, Heleena Moni. "Effects of different diet administration on energy balance, metabolic efficiency and inflammatory state in an animal model." Tesi di dottorato, 2018. http://www.fedoa.unina.it/12287/1/BottuHeleenaMoni.pdf.

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My research project aims to evaluate the possible beneficial effects of Omega (ω)-3 polyunsaturated fatty acids (PUFA) administration in an experimental animal model. I performed the research activity with two different experimental approaches. In the first experimental project, it was used an animal model with obesity-diet induced. Male Wistar rats were fed, for 6 weeks, with three different diets: standard diet (control); HFD enriched with saturated fatty acids (lard); HFD enriched with ω-3 (PUFA) derived from fish oil. In the second experimental project, the rats were fed with standard diet

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15

Paixão, Joana Isabel Félix. "Malvidin 3-glucoside, a dietary anthocyanin, contributes to the balance between pro- and anti-inflammatory mediators in human endothelial cells: a potential role in the atherogenic process." Master's thesis, 2014. http://hdl.handle.net/10316/37454.

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16

RUSSO, TIZIANA. "Balanite Xerotica Obliterans in età pediatrica :meccanismi di danno biomolecolare e ricerca di strategie farmacologiche innovative." Doctoral thesis, 2017. http://hdl.handle.net/11570/3104657.

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AIM : Balanitis xerotica obliterans (BXO) is a chronic inflammatory skin disorder of unclear etiology, it is considered the male genital variant of lichen sclerosus. The etiology and the exact molecular mechanisms underlying the disease are still unknown. The histopathology of BXO is characterized by alterations in the epidermis and dermis as well as inflammatory cell infiltration. In this regard several factors may be involved in underling molecular changes associated with inflammatory response. Antiinflammatory drugs are commonly used in pre-operative setting to decrease the inflammatory/au

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