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1

Nébié, Issa, Nick J. Edwards, Alfred B. Tiono, Katie J. Ewer, Guillaume S. Sanou, Issiaka Soulama, Souleymane Sanon, et al. "Assessment of Chimpanzee Adenovirus Serotype 63 Neutralizing Antibodies Prior to Evaluation of a Candidate Malaria Vaccine Regimen Based on Viral Vectors." Clinical and Vaccine Immunology 21, no. 6 (April 16, 2014): 901–3. http://dx.doi.org/10.1128/cvi.00723-13.

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ABSTRACTPrior to a chimpanzee adenovirus-based (ChAd63) malarial vaccine trial, sera were collected to assess ChAd63-specific neutralizing antibody titers in Banfora (Burkina Faso). The low neutralizing antibody titers reported in both adults and children (median titers, 139.1 and 35.0, respectively) are encouraging for the potential use of ChAd63 as a malarial vaccine vector.
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César, Jean, Jérémy Bouyer, Laurent Granjon, Massouroudini Akoudjin, Laure Guerrini, and Dominique Louppe. "Les relictes forestières de la falaise de Banfora : un peuplement original au voisinage de Bobo-Dioulasso, Burkina Faso." BOIS & FORETS DES TROPIQUES 305, no. 305 (September 1, 2010): 43. http://dx.doi.org/10.19182/bft2010.305.a20437.

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La falaise de Banfora est d'une grande richesse floristique et faunique. Ses forêts renferment des espèces endémiques mais aussi des espèces remarquables telles que Albiziadinklagei, Acridocarpus chevalieri ou Warneckea fascicularis qui ne se retrouvent nulle part ailleurs au Burkina Faso. C'est aussi le cas de certaines espèces d'insectes telles que Dicronorhina kouensis ou Stephanorhina guttata. Toutefois, ces forêts sont menacées, particulièrement autour de Bobo-Dioulasso où la faune d'origine a déjà partiellement disparu. Les sites de la falaise sont comparés entre eux ainsi qu'avec d'autres forêts de la région de Bobo-Dioulasso. Une très grande diversité biologique s'observe d'une forêt à l'autre. La dispersion des espèces suggère que ces forêts résulteraient de masses forestières plus vastes dont elles seraient les relictes. La végétation forestière des falaises aurait trois origines : la forêt dense sèche, caractérisée par Guibourtia copallifera, qui pourrait représenter le fond forestier originel avant l'invasion de la flore des savanes ; la forêt dense humide, représentée par la majorité des espèces ripicoles, qui serait issue de la masse forestière humide en suivant le réseau hydrographique ; un fond de flore montagnarde inféodé aux falaises gréseuses, dont l'unique représentant serait Warneckea fascicularis, auquel il serait possible de rattacher les espèces de rochers. La communauté de rongeurs des sites forestiers de la falaise de Banfora est un mélange d'espèces typiquement forestières (en particulier Praomys rostratus) dans les zones les moins perturbées et d'espèces très anthropophiles (comme Rattus rattus) sur les sites les plus dégradés par l'action humaine. La plupart des espèces d'insectes ont probablement pour origine la forêt humide de Côte d'Ivoire, avec des influences maliennes, comme Coeliades aeschylus, ou togolaises, comme Dicronorhina kouensis, espèces qui se rencontrent surtout en zone de savane guinéenne, à proximité des forêts galeries. Ces espèces n'étant pas observées au Sud, ni respectivement à l'Est et à l'Ouest du Burkina Faso, la falaise de Banfora pourrait constituer un point de rencontre entre différentes faunes, ce qui en fait toute la richesse. (Résumé d'auteur)
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Álvaro, J. Javier, and Daniel Vizcaïno. "Proterozoic microbial reef complexes and associated hydrothermal mineralizations in the Banfora Cliffs, Burkina Faso." Sedimentary Geology 263-264 (July 2012): 144–56. http://dx.doi.org/10.1016/j.sedgeo.2011.11.005.

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4

César, Jean, Jérémy Bouyer, Laurent Granjon, Massouroudini Akoudjin, and Dominique Louppe. "Les relictes forestières de la falaise de Banfora : les dégradations au voisinage de Bobo-Dioulasso, Burkina Faso." BOIS & FORETS DES TROPIQUES 308, no. 308 (June 1, 2011): 5. http://dx.doi.org/10.19182/bft2011.308.a20474.

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Le suivi de la végétation et l'inventaire de bioindicateurs animaux, micromammifères et insectes, a permis de dresser un bilan des dégradations environnementales dans trois villages situés à proximité de Bobo-Dioulasso. Les dégâts apparemment les plus graves résultent de la coupe des arbres pour le bois de feu et de l'extraction minière du sable et du gravier pour les constructions. Ces activités sont la conséquence du développement urbain. Les dégradations environnementales dues à l'agriculture et à l'élevage paraissent moins importantes. L'ensemble de ces activités humaines fait que les terres maraîchères de Koro sont en train de disparaître, tout comme la forêt classée de Koua. Les suivis et inventaires, réalisés pour mieux cerner cette évolution anthropique de l'environnement, montrent que les espèces animales réagissent à cette forte perturbation du milieu amplifiée par les phénomènes fréquents d'érosion. En conclusion de cette étude, des mesures de protection et de reboisement sont proposées pour limiter l'érosion dans les champs et sur les berges de la rivière. L'extraction minière des matériaux de construction pourrait aussi être organisée pour moins impacter l'environnement ; mais cela risque d'être difficile à mettre en oeuvre car les intérêts individuels priment face aux besoins collectifs. (Résumé d'auteur)
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Savadogo, Léon G. Blaise, Ouédraogo Salimata, Cécile Tamini, Maurice Kinda, and Philipe Donnen. "Characteristics of Severely Anemic Pregnant Women and Perinatal Outcomes in Banfora Regional Hospital, Burkina Faso: An Epidemiological Study." Open Journal of Obstetrics and Gynecology 04, no. 05 (2014): 234–38. http://dx.doi.org/10.4236/ojog.2014.45038.

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6

Adama, Ouattara, Yaméogo Relwendé Barnabé, Kaboré Francois Xavier Gueswendé, Kiemtoré Sibraogo, Kain Dantola Paul, Sawadogo Yobi Alexi, Dao Yissou, et al. "Prognosis of Misgav-Ladach Caesarean Sections in an African Environment: Case of the Banfora Regional Hospital in Burkina Faso about 110 Cases." Open Journal of Obstetrics and Gynecology 07, no. 09 (2017): 1006–15. http://dx.doi.org/10.4236/ojog.2017.79101.

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7

Lankoandé, Benjamin, Anne Mette Lykke, Joseph Issaka Boussim, and Amadé Ouédraogo. "Structure, plant diversity and future management of Pentadesma butyracea stands, an endangered oil tree species in Burkina Faso, West Africa." Forestry: An International Journal of Forest Research 92, no. 5 (May 31, 2019): 591–98. http://dx.doi.org/10.1093/forestry/cpz034.

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Abstract This paper aims to assess the population structure of Pentadesma butyracea Sabine, a local oil tree species and to analyze the occurrence of woody plants in P. butyracea natural stands. Data were collected in 41 plots of 50 × 20 m across natural stands of P. butyracea in two regions of the south-Sudanian phytogeographic zone of Burkina Faso. Stem diameter, total height and tree health were recorded and the woody plant diversity was assessed. Stand data were calculated and the diameter structure was analyzed at the regional level using the Weibull distribution. Significant differences (P < 0.05) were found in density and basal area between regions. In both regions, 32 per cent of trees show signs of poor health. The diameter distributions of individuals showed a structure close to a reverse J-shape (c < 1). Natural stands of P. butyracea exhibit good natural regeneration, but the large trees in the sampled populations commonly had poor health. The data may indicate early signs of stands of P. butyracea changing into savanna in the Banfora region as a consequence of human activities and climate deterioration. P. butyracea is a dominant species in riparian forest, its conservation has a potential to restore the riparian forest; appropriate management guidance and support that involves local communities is required to ensure sustainable management.
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Soulama, Issiaka, and Sodiomon B. Sirima. "OC 8459 ASSESSMENT OF PARASITE CLEARANCE AFTER REPEATED TREATMENT WITH ARTESUNATE AMODIAQUINE, DIHYDROARTEMISININ-PIPERAQUINE, PYRONARIDINE-ARTESUNATE IN MALARIA PATIENTS IN BURKINA FASO." BMJ Global Health 4, Suppl 3 (April 2019): A7.2—A8. http://dx.doi.org/10.1136/bmjgh-2019-edc.17.

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BackgroundReports from Southeast Asia showed delayed parasite clearance after treatment with known artemisinin-based combination therapies (ACTs), the first-line treatment for malaria. We then carried out a study in the framework of the WANECAM clinical trial to assess comparatively the parasite clearance time and rate from P. falciparum malaria patients repeatedly treated with the artesunate-amodiaquine (ASAQ), dihydroartemisinin-piperaquine (DHA-PQ) and artesunate-pyronaridine (PYR).MethodsA randomised, phase III/IV comparative, multicentre, open-label, parallel 3-arms trial was conducted in Banfora Health District area comparing the efficacy of a three-day regimen of DHA-PQ, PYR with ASAQ for the treatment of children (above 6 months) and adults with uncomplicated falciparum malaria. From August 2012 to December 2013, each randomised patient was followed up for 42 days over a period of two years. Treatment was directly observed, and blood smear samples were collected twice daily (12 hour±2 hour) until parasite clearance.The endpoints of the present sub-study were parasite clearance rate and time. The secondary endpoints included PCR-corrected and uncorrected cure rates.ResultsOut of 2843 screened patients, 763 were recruited for parasite clearance endpoint analyses. The median parasite clearance time (PCT) was 24.1 hour (2-sided 95% CI, 24.0 to 24.2 hour), 23.9 hour (2-sided 95% CI, 23.8 to 24.0 hour) and 24.2 hour (2-sided 95% CI, 24.1 to 24.5 hour), in PYR and DHA-PQ, respectively. The PCR-corrected efficacy rates were estimated at 99.8%; 99.7%; 99.9%, at day 28% and 99.3%; 99.7%–99.9% in PYR, ASAQ and DHA-PQ, respectively.ConclusionThe parasite clearance times were comparable among the three ACT arms of treatment and their efficacy was comparable and higher than 99%. There was no delay in parasite clearance time (PCT ≥72 hour).
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Sereme, D., B. J. Neya, M. Bangratz, C. Brugidou, and I. Ouedraogo. "First Report of Rice stripe necrosis virus Infecting Rice in Burkina Faso." Plant Disease 98, no. 10 (October 2014): 1451. http://dx.doi.org/10.1094/pdis-06-14-0626-pdn.

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Rice stripe necrosis virus (RSNV) was first described in 1977 as a new virus infecting rice in Cote d'Ivoire (3) and was subsequently observed in Liberia, Nigeria, and Sierra Leone (2). RSNV is a soil-borne virus transmitted by the fungus Polymyxa graminis (1) and belongs to the genus Benyvirus (4). During a survey carried out in April of 2013, severe symptoms characterized by seedling death, severe plant malformation, and foliar striping were observed on rice plants in an experimental field of INERA at Banfora located in western Burkina Faso. Disease incidence in the field was estimated to be 80 ± 5%. The symptoms of disease were successfully transmitted to the susceptible rice (Oryza sativa) cultivar IR64 by soil transmission experiments (1). RSNV was detected by ELISA using a polyclonal antiserum (1), kindly provided by Dr. Denis Fargette, IRD, Montpellier, France. Total nucleic acid was extracted with TRIzol reagent (Invitrogen) from IR64 and field infected samples. The presence of the virus was confirmed by RT-PCR using primers 5′-CATCTTGTCGAGATGAG-3′ and 5′-GCGTTGTCTTTATCAGTG-3′ for specific sequences flanking the RNA2 CP gene. The RT-PCR product was directly sequenced and the sequence was deposited in GenBank (Accession No. LK023710). Sequence analysis showed that the CP gene of the RSNV isolate from Burkina Faso shared the highest nucleotide sequence identity (97.6%) with the known RSNV CP gene sequence from the Colombian isolate (EU099845) available in GenBank, confirming the presence of RSNV in the rice crops in Burkina Faso. To our knowledge, this is the first confirmed report of RSNV in Burkina Faso. Further studies are needed to determine its incidence and spread in the country. Detection of RSNV in Burkina Faso signals the urgent need for adoption of appropriate measures to restrict the spread and impact of this virus within Africa. References: (1) C. Fauquet and J. C. Thouvenel. Proc. Acad. Sci. Ser. D 296:575, 1983. (2) C. Fauquet et al. Develop. Appl. Biol. 2:71, 1988. (3) D. Louvel and J.-M. Bidaux. Agronomie Tropicale 32:257, 1977. (4) I. Lozano and F. Morales. Eur. J. Plant Pathol. 124:673, 2009.
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Caron, Jean-Bernard. "Banffia constricta, a putative vetulicolid from the Middle Cambrian Burgess Shale." Transactions of the Royal Society of Edinburgh: Earth Sciences 96, no. 2 (June 2005): 95–111. http://dx.doi.org/10.1017/s0263593300001255.

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ABSTRACTAlthough Banffia constricta was first described in 1911, the affinities of this soft-bodied fossil animal have remained unclear. Banffia is redescribed here, on the basis of over 300 specimens. Banffia has a bipartite body measuring up to 10 cm in length. The entire body is axially twisted along a spiral, clockwise as seen from the front. The anterior section consists of two fused carapace-like units with a prominent crown-like structure at the anterior end surrounding the mouth. This crown-like structure is composed of three concentric circlets. A single antenniform outgrowth lies posterior to the mouth. The posterior section of Banffia is composed of 40 to 50 lightly sclerotised segments. The anus is terminal, and situated in a caudal notch. The gut is straight. Simple serially repeated structures along the gut may represent metameric mid-gut diverticulae. Banffia is considered to have been an epibenthic gregarious animal and possibly a deposit-feeder.Banffia is putatively classified as an end-member of the phylum Vetulicolia, in a new class, the Banffozoa. If the vetulicolids represent a stem-group deuterostome, the absence of gills and a possible endostyle in Banffia is problematic. The presence of mid-gut diverticulae in Banffia may represent a link with the protostomes.
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BRUYNS, PETER V., CORNELIA KLAK, and PAVEL HANÁČEK. "An account of Ceropegia sect. Chamaesiphon (Apocynaceae) in Moçambique with new records and two new species." Phytotaxa 364, no. 2 (August 9, 2018): 111. http://dx.doi.org/10.11646/phytotaxa.364.2.1.

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Two new species of Ceropegia sect. Chamaesiphon H.Huber from Moçambique, C. cyperifolia Bruyns and C. gracilidens Bruyns, are described and illustrated. A brief account of eight other species recorded for the first time from Moçambique is given and notes are provided on the little-known Ceropegia simplex (Schltr.) Bruyns, which has not been collected since Schlechter’s original gathering in 1898. A key is presented to all 11 species in Moçambique. Brachystelma simplex subsp. banforae Lebrun & Stork from West Africa is raised to specific level as Ceropegia banforae (Lebrun & Stork) Bruyns so that Ceropegia simplex is confined to material from Moçambique. Ceropegia vahrmeijeri (R.A.Dyer) Bruyns is reduced to synonymy under C. cupulata (R.A.Dyer) Bruyns and Brachystelma mortonii C.C.Walker under Ceropegia plocamoides (Oliver) Bruyns.
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Ward, Nigel. "Principles of International Financial Law Colin Banford." Law and Financial Markets Review 5, no. 4 (July 2011): 313. http://dx.doi.org/10.5235/175214411796505633.

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Silva, Laianna Victoria Santiago, Patrícia Sayuri de Lima Tanaka, and Maria Raquel Gomes Maia Pires. "BANFISA e (IN)DICA-SUS na graduação em saúde: o lúdico e a construção de aprendizados." Revista Brasileira de Enfermagem 68, no. 1 (February 2015): 124–30. http://dx.doi.org/10.1590/0034-7167.2015680117p.

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Diante dos desafi os à formação crítica de profi ssionais de saúde, este artigo questiona se os jogos BANFISA e (IN)DICA-SUS potencializam a criatividade, o trabalho em equipe e a autonomia na graduação em saúde. Objetivos: analisar os aprendizados construídos durante as partidas dos jogos pelos estudantes da disciplina Gestão de Políticas Públicas em Saúde da Universidade de Brasília. Método: pesquisa de caráter exploratório, descritivo, abordagem qualitativa, com 26 estudantes de diversos cursos de graduação em saúde, uso de questionário e observação participante. Resultados: os participantes reinventaram regras, relacionaram assuntos tratados nos jogos à realidade, interagiram com colegas e se divertiram ao longo da partida. Na comparação dos jogos quanto à ludicidade, o BANFISA se mostrou mais atrativo que o (IN)DICA-SUS, embora se complementem. Conclusão: Compreendeu-se que os aprendizados construídos pelos alunos vão além dos conteúdos da disciplina, envolvem a participação ativa em grupo e a criatividade.
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Conway Morris, Simon, Susan L. Halgedahl, Paul Selden, and Richard D. Jarrard. "Rare primitive deuterostomes from the Cambrian (Series 3) of Utah." Journal of Paleontology 89, no. 4 (July 2015): 631–36. http://dx.doi.org/10.1017/jpa.2015.40.

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AbstractThe fossil record of early deuterostome history largely depends on soft-bodied material that is generally rare and often of controversial status. Banffiids and vetulicystids exemplify these problems. From the Cambrian (Series 3) of Utah, we describe specimens of Banffia episoma n. sp. (from the Spence Shale) and Thylacocercus ignota n. gen. n. sp. (from the Wheeler Formation). The new species of Banffia Walcott, 1911 shows significant differences to the type species (B. constricta Walcott, 1911) from the Cambrian (Series 3, Stage 5) Burgess Shale, notably in possessing a prominent posterior unit but diminished anterior section. Not only does this point to a greater diversity of form among the banffiids, but also B. episoma indicates that the diagnostic median constriction and crossover of either side of the body are unlikely to be the result of taphonomic twisting but are original features. Comparisons extend also to the Cambrian (Series 2) Heteromorphus Luo and Hu in Luo et al., 1999 and, collectively, these observations support an assignment of the banffiids to the vetulicolians. The new taxon T. ignota represents the first discovery of a vetulicystid from beyond China and also significantly extends its stratigraphic range from Series 2 Cambrian into Series 3 Cambrian. Despite overall similarities in bodyplan, T. ignota differs from other vetulicystids in a number of respects, notably the possession of an anterior zone with broad tentacle-like structures. This new discovery is consistent with the vetulicystids representing stem-group ambulacrarians.
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Yan, Zhe. "An Ethical Glimpse into Nursing Home Care Work in China: Mei banfa." Ethics and Social Welfare 14, no. 4 (October 1, 2020): 417–24. http://dx.doi.org/10.1080/17496535.2020.1839182.

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Pires, Maria Raquel Gomes Maia, and Leila Bernarda Donato Gottems. "Recriar-se de subjetividades críticas na formação e no trabalho interprofissional." JMPHC | Journal of Management & Primary Health Care | ISSN 2179-6750 8, no. 3 (September 19, 2018): 34. http://dx.doi.org/10.14295/jmphc.v8i3.647.

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O Recriar-se (arte, lúdico e tecnologias educativas na saúde) é uma linha de produção científica do Núcleo de Pesquisa em Promoção da Saúde e Projetos Inclusivos, pertencente ao Centro de Estudos Avançados e Multidisciplinares da Universidade de Brasília (Nesprom/Ceam/UnB). Nosso compromisso é produzir conhecimentos e tecnologias lúdico- educativas para a formação e a prática de profissionais de saúde e de outras áreas, com ênfase na reinvenção de subjetividades críticas em suas dimensões éticas, estéticas, epistêmicas, política e social. O objetivo do trabalho é relatar as experiências de pesquisas do Recriar-se no fomento de subjetividades críticas de estudantes e profissionais, aplicadas aos diversos cenários do ensino e do trabalho interprofissional. Trata-se de um relato de experiência em pesquisa, produção tecnológica e narrativas lúdico-educativas de abordagem interdisciplinar e multiprofissional oriunda da referida linha. Nos últimos sete anos, diversos projetos de pesquisas originaram três tecnologias lúdico-educativas (jogos de tabuleiro (IN)DICASUS, Banfisa e Violetas), assim como a série ‘Didáticos-para-Recriar-se’, contendo 38 produções oriundas das experiências de pesquisa, de ensino e de extensão, articuladas às manifestações da arte e do lúdico, com ricas possibilidades de reinvenção sensível, ética e política dos participantes.
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Ouédraogo, Salfo, Tata Kadiatou Traoré, Benjamin Ouedraogo, Boladé Constantin Atchadé, Adjaratou Coulibaly, Marius Lompo, Sylvin Ouédraogo, and Rasmané Semdé. "Phytochemical Characteristics and Pharmacological Properties Studies of the Powders of Punica granatum L. (Lythraceae) Leaves from Seven Regions of Burkina Faso with a View to Standardizing." Journal of Advances in Medical and Pharmaceutical Sciences, February 25, 2021, 1–11. http://dx.doi.org/10.9734/jamps/2021/v23i130212.

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Introduction: Punica granatum is a plant used in traditional and alternative medicine for the management of several diseases. Objective: The objective of the present work is to compare the phytochemical characteristics and the antioxidant properties of extracts of leaves powders of Punica granatum L. collected for standardization. Methodology: We worked on seven samples of powders of leaves of Punica granatum L collected in seven different regions of Burkina Faso. Two types of extracts, aqueous and hydroethanolic were prepared with each sample. We performed a phytochemical screening by thin layer chromatography (TLC), then determined the content of the various extracts in total phenolic and flavonoids as well as a study of the antioxidant activity of the aqueous and hydro-ethanolic extracts of the plant. Results: Fourteen extracts of Punica granatum are obtained and these contain secondary metabolites such as tannins, sterols, triterpenes, saponosides and flavonoids. The anti-free radical activities at the DPPH* were more important in the samples from the towns of Dedougou, Banfora and Fada. The anti-free radicals at ABTS of extracts from the towns of Manga, Banfora, Fada and Kaya were found to be the most active. The FRAP test shows better activity of samples from the cities, Manga, Dedougou and Banfora. Conclusion: At the end of this work, the towns of Dedougou and Banfora may be the sites to be favored as harvesting sites because their samples were the richest in phenolic compounds and had the best antioxidant activities compared to the tests carried out.
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Ilboudo, Hermann, Sâga Sawadogo, Gounwendmanaghre Hubert Zongo, Seta Naba, Urbain Wenmenga, and Martin Lompo. "Geochemistry and geodynamic constraint of volcanic and plutonic magmatism within the Banfora Belt (Burkina-Faso, West-Africa): contribution to mineral exploration." Geological Society, London, Special Publications, September 28, 2020, SP502–2019–86. http://dx.doi.org/10.1144/sp502-2019-86.

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AbstractPredominant volcano-plutonic (mafic–felsic) activity is expressed in the eastern Banfora Belt. The geochemical signature shows different geodynamic settings: (1) mafic rocks are tholeiitic, subalkaline and show high-Mg tendency, whereas pyroxenolite (MgO c. 15.4 wt%) has komatiite affinity; (2) felsic volcanic rocks are subalkaline; and (3) granitoids surrounding the Banfora Belt are alkaline to calc-alkaline, high K, peraluminous to metaluminous. The geochemistry of mafic volcanic rocks shows an unusual evolution from Mid Oceanic Ridge Basalt to Arc-related. The Western Granite and Eastern Granites were emplaced by fractional crystallization and partial melting, respectively, but sourced from igneous protolith (I-type magma) in a volcanic arc setting. The Sodingue granite was emplaced by fractional crystallization from A-type magma in a ‘within-plate setting’. Two-mica S-type granites located at the central portion of the belt relate to syn-collisional fractional crystallization. The paper highlights the complexity of the magma process through a diversity of sources, geochemical patterns and tectonic settings. An emphasis on the komatiite affinity of mafic magma is a challenge for related commodities, such as copper and gold resources.
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Nikiema, Séni, Samuel Sindié Sermé, Salif Sombié, Amidou Diarra, Noelie Bere Henry, Emilie Salimata Badoum, Sam Aboubacar Coulibaly, et al. "Prevalence of Plasmodium falciparum Chloroquine Resistance Transporter (Pfcrt76T) Mutation Associated with Antimalarial Drug Resistance in Two Different Epidemiological Setting (Banfora and Saponé) in Burkina Faso Few Years after the Implementation of Artemisnine Based Combination Therapy (ACTs)." International Journal of Pathogen Research, January 2, 2020, 1–11. http://dx.doi.org/10.9734/ijpr/2019/v3i330094.

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Introduction: In spite of considerable progress, malaria remains a public health problem in many areas, particularly in sub-Saharan Africa. One major complexity of malaria disease is caused by the development and the spread of vector and parasite resistance to insecticides and antimalarial drugs respectively. The Pfcrt76T gene mutation has been validated as a marker conferring resistance to chloroquine and other antimalarial drugs. The extension of Plasmodium falciparum resistance to commonly used antimalarial drugs (chloroquine, sulfadoxine-pyrimethamine) led to the adoption and the use of artemisinin-based combinations in Burkina Faso since 2005. Aims: The present study was initiated to assess the prevalence of the Pfcrt76T mutation in two different malaria epidemiological setting after a decade of introduction of artemisinin-based combination therapies (ACTs) in Burkina Faso. Methodology: The study population consisted of 181 uncomplicated malaria patients recruited in Banfora and Saponé health districts in 2012 and 2013. Blood samples were collected from finger prick on filter paper, dried and sent to the Molecular Biology Laboratory at Centre National de Recherche et de Formation sur le Paludisme (CNRFP) for molecular analyzes. DNA of Plasmodium falciparum was extracted with DNA extraction kit (Qiagen®) and the Pfcrt76T mutation was determined based on Polymerase Chain Reaction / Restriction Fragment Length Polymorphism technique (RFLP). Results: The results of this study showed that the frequency of the pfcrt76T mutant allele (33.7%) was statistically lower than the Pfcrt76K wild-type allele (57.4%) in the study area. Moreover, the prevalence of Pfcrt76T mutation was neither associated with the patient age nor with the parasite density while a significant difference was observed between the two epidemiological setting, Banfora and Saponé. Conclusion: The findings of this study has shown a drop in the prevalence of mutant parasites Pfcrt76T in both the study area eight years after the introduction of ACTs compared to previous studies.
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Badoum, Emilie S., Samuel S. Sermé, Jean B. Yaro, Sam A. Coulibaly, Désiré Kargougou, Amidou Diarra, Amidou Z. Ouédraogo, et al. "Abnormalities of Hemoglobin and Glucose-6-Phosphate-Dehydrogenase Deficiency in Children with Uncomplicated Malaria and Living in Banfora and Saponé, Two Different Malaria Setting of Burkina Faso." International Journal of TROPICAL DISEASE & Health, July 26, 2019, 1–10. http://dx.doi.org/10.9734/ijtdh/2019/v37i330168.

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Aims: The aim of this study is to assess the prevalence of hemoglobin abnormalities and G6PD deficiency and their respective influence on anemia occurring in less than five years old children with clinical P. falciparum malaria living in Burkina Faso. Study Design: The study was a cross-sectional survey with descriptive focus conducted from December 2010 to January 2013 in Saponé health district and from May to October 2011 in Banfora health district. Clinical and laboratory data were collected. Blood smears on slides for malaria diagnosis by microscopy, hemoglobin level and filter paper for the detection of human genetic factors were performed. Methodology: A total of 386 subjects from Saponé (131) and Banfora (255) were enrolled. DNA collected from each sample was extracted using chelex-100 method and the human genetic resistance factors background was assessed by RFLP-PCR. Abnormal hemoglobin patients were classified as NonAA while AA was defined the normal hemoglobin. Results: In this study, 70.98% (274/386) were classified normal hemoglobin (AA) while 29.02% (112/386) of subjects were carrying at least one abnormal (NonAA) allele: 24.35%AC, 3.63% AS, 0.78%CC and 0.26%SC. G6PD deficiency was 9.59% (37/386) among which, 4.92% for male and 4.66% in female. However, this gender difference was not statistically significant (p=1.00). 319/367 (86.92%) of the patients were anemic (59.4% with moderate anemia and 20.98% with mild anemia). The prevalence of anemia in G6PD deficient subjects was 83.33% (of which 58.33% were moderate anemia and 22.22% mild anemia). The difference between types of hemoglobin (p=0.64) in the occurrence of anemia (AA 87.64% and Non AA 85.18%) was not statistically significant. Conclusion: This study showed that the prevalence of these genetic factors was relatively low among children with clinical falciparum malaria with high parasite density. In addition, these factors appear to have no effect on anemia.
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Williams, Jessica, Lori Flood, Giorgio Praulins, Victoria A. Ingham, John Morgan, Rosemary Susan Lees, and Hilary Ranson. "Characterisation of Anopheles strains used for laboratory screening of new vector control products." Parasites & Vectors 12, no. 1 (November 5, 2019). http://dx.doi.org/10.1186/s13071-019-3774-3.

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Abstract Background Insecticides formulated into products that target Anopheles mosquitos have had an immense impact on reducing malaria cases in Africa. However, resistance to currently used insecticides is spreading rapidly and there is an urgent need for alternative public health insecticides. Potential new insecticides must be screened against a range of characterized mosquito strains to identify potential resistance liabilities. The Liverpool School of Tropical Medicine maintains three susceptible and four resistant Anopheles strains that are widely used for screening for new insecticides. The properties of these strains are described in this paper. Methods WHO tube susceptibility bioassays were used for colony selection and to screen for resistance to the major classes of public health insecticides. Topical and tarsal contact bioassays were used to produce dose response curves to assess resistance intensity. Bioassays with the synergist piperonyl butoxide were also performed. Taqman™ assays were used to screen for known target site resistance alleles (kdr and ace-1). RT-qPCR was used to quantify expression of genes associated with pyrethroid resistance. Results Pyrethroid selection pressure has maintained resistance to this class in all four resistant strains. Some carbamate and organophosphate resistance has been lost through lack of exposure to these insecticide classes. The Anopheles gambiae (sensu lato) strains, VK7 2014, Banfora M and Tiassalé 13 have higher levels of pyrethroid resistance than the An. funestus FUMOZ-R strain. Elevated expression of P450s is found in all four strains and the 1014F kdr mutation is present in all three An. gambiae strains at varying frequencies. Tarsal contact data and overexpression of CYP4G16 and SAP2 suggest penetration barriers and/or sequestration also confer resistance in Banfora M. Conclusions Continual selection with deltamethrin has maintained a stable pyrethroid-resistant phenotype over many generations. In conjunction with a standardized rearing regime, this ensures quality control of strains over time allowing for robust product comparison and selection of optimal products for further development. The identification of multiple mechanisms underpinning insecticide resistance highlights the importance of screening new compounds against a range of mosquito strains.
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Ouattara, Fatoumata. "Gouvernances quotidiennes au cœur des structures de santé. Les cas d’Orodara et de Banfora, Burkina Faso." Bulletin de l’APAD, no. 23-24 (December 1, 2002). http://dx.doi.org/10.4000/apad.145.

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23

Djiguimdé, Pierre Windinmanégdé, Ibrahim Abib Diomandé, Ahgbatouhabéba Ahnoux-Zabsonré, Konan Virgile Koffi, Tierinyê Armand Meda, Gossé François Diomandé, Jerôme Sanou, Gertude Meda-Hien, Paté Sankara, and Nonfounikoun Meda. "Résultats de la chirurgie avancée de la cataracte par tunnélisation: à propos de 262 cas réalisés au CHR de Banfora (Burkina Faso)." Pan African Medical Journal 22 (2015). http://dx.doi.org/10.11604/pamj.2015.22.366.8416.

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24

Sombié, Salif, Samuel Sindié Sermé, Aïssatou Diawara, Mame Massar Dieng, Amidou Diarra, Emilie S. Badoum, Sam Aboubacar Coulibaly, et al. "Distribution of msp1, msp2 and eba175 Allelic Family According to Hemoglobin Genotype and G6PD Type from Children with Uncomplicated Malaria in Banfora Heath District (Burkina Faso)." Journal of Scientific Research and Reports, February 10, 2020, 36–47. http://dx.doi.org/10.9734/jsrr/2020/v26i130212.

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Aim: The present study aimed to evaluate the Plasmodium falciparum genetic diversity according to the host hemoglobin and G6PD genetic variants during the course of malaria in infected children aged from 2 to 10 years and living in endemic area in Burkina Faso. Study Design: The study was designed as a longitudinal follow up conducted between May 2015 and February 2016 in Banfora health district, Burkina Faso. Methodology: We included 136 subjects (73 males and 63 females; age range from 2-10 years). Blood thick and thin film was done by capillary blood. Venous blood was collected for DNA extraction. Malaria diagnosis was done by microscopy. Human and parasite DNA were extracted based on Qiagen kit procedure. Then, hemoglobin and G6PD were genotyped by RLFP-PCR while the msp1, msp2 and eba175 genes were typed by a nested PCR. All PCR products were analyzed by electrophoresis on a 1.5-2% agarose gel and alleles categorized according to the molecular weight. Results: The prevalence of hemoglobin type was 19.11% for abnormal hemoglobin and 80.9% for normal hemoglobin carriage. The prevalence of G6PD type was 91.18% for normal and 8.82% for G6PD deficiency carriage, respectively. The prevalence of msp1 allelic families was 81.60%, 80.80% and 67.20% for k1, ro33 and mad20 respectively while for msp2 gene, fc27 and 3D7 allelic family the prevalence was 70.53% and 69.64% respectively. The eba175 allelic families’ distribution showed 77.31% and 40.21% for fcr3 and Camp respectively. There was no difference in multiplicity of infection (MOI) according to hemoglobin genotypes and G6PD types. We found that k1 was the predominant allelic family of msp1 in normal hemoglobin genotype (AA) and normal G6PD type. The mixed infection of eba175 was statistically higher in abnormal hemoglobin (p=0.04). There was no statistical difference between fcr3 and camp prevalence excepted in G6PD deficient type. The polymorphism results showed that the prevalence of 450 bp in fc27 was statistically significantly higher in normal hemoglobin variant carriers (AA) than abnormal hemoglobin carriers (p=2.10 -4)). However, the prevalence of 350 bp in fc27 was statistically higher in normal G6PD than deficient G6PD carriers (p=0.034). Conclusion: Our result showed that the distribution of msp1 and eba75 polymorphism could be influenced by hemoglobin and G6PD variants. These results suggest that hemoglobin and G6PD could influence P. falciparum genetic diversity.
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Sombié, Salif, Emilie S. Badoum, Samuel Sindié Sermé, Aïssatou Diawara, Amidou Diarra, Sam Aboubacar Coulibaly, Noelie Henry/Béré, et al. "The Impact of Human Genetic Factors (G6pd and Type of Hemoglobin) on the Course of Uncomplicated Malaria Infection in Children Aged from 2 to 10 Years Living in the Banfora Health District in Burkina Faso." International Journal of TROPICAL DISEASE & Health, June 19, 2019, 1–12. http://dx.doi.org/10.9734/ijtdh/2019/v36i430148.

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Aims: The aim of this study was to assess the impact of hemoglobin polymorphisms and G6PD deficiency on the course of uncomplicated malaria infection in children aged from 2 to 10 years in Burkina Faso. Study Design: The study was conducted as a longitudinal study in Banfora health district. A total of 150 children aged from 2 to 10 years was enrolled and followed up between May 2015 and February 2016. Blood samples were collected at four different time points: before infection (Visit 1), during asymptomatic parasitemia (Visit 2), during symptomatic parasitemia (Visit 3) and three weeks after treatment (Visit 4). Clinical examination, hematology parameters and malaria diagnosis using microscopy were performed. Hemoglobin and G6PD typing were done using PCR-RFLP. Hemoglobin AA genotypes were defined as normal hemoglobin while Hemoglobin AC, AS and SS were defined as abnormal hemoglobin (hb non-AA). Results: The prevalence of hemoglobin (hb) genotypes was 81.21% for AA while hb non-AA genotypes were estimated at 18.79% (12.08% for hbAC, 6.04% for hbAS and 0.67% for HbSC). The prevalence of G6PD genotypes was 89.26% and 10.74% for normal G6PDn and G6PD deficiency respectively. The prevalence of asymptomatic carriers of P. falciparum was not affected neither by the genotypes of Hemoglobin, nor by the G6PD deficiency. Conversely, the risks of developing uncomplicated malaria in G6PD deficiency (G202A) group, was significantly lower (p = 0.04). The results showed a significant difference (p˂0.0001) in the means of P. falciparum parasite densities between asymptomatic and symptomatic phase in Hemoglobin AA genotypes carriers while the means of parasite density was comparable in non-Hemoglobin AA carriers. Conclusion: Our study showed that G6PD deficiency protects against clinical malaria while P. falciparum parasite density increasing was correlated with carrying hemoglobin genotypes AA.
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Akyol, Ayşe Sadıka, Akkan Avci, Müge Gülen, Begüm Şeyda Avci, and Salim Satar. "İskemik İnmede TOAST ve BANFORD Sınıflaması ile Hemogram Parametrelerinin Mortalite Açısından Karşılaştırılması." Dicle Tıp Dergisi, April 7, 2019, 97–107. http://dx.doi.org/10.5798/dicletip.534840.

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27

"Banffia constricta, a putative vetulicolid from the Middle Cambrian Burgess Shale." Earth and Environmental Science Transactions of the Royal Society of Edinburgh 96, no. 02 (June 2005): 95. http://dx.doi.org/10.1017/s0263593305000052.

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28

Mazzotti, Antonio, Alberto Di Martino, Patrizia Tomba, Anna Viganò, Giuseppe Geraci, and Cesare Faldini. "The Casuccio-Santacroce-Banfo knee arthroscope: an avant-garde Italian tale in the history of arthroscopy." International Orthopaedics, June 23, 2021. http://dx.doi.org/10.1007/s00264-021-05118-x.

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