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Journal articles on the topic 'Basal laminar deposit'

Author: Grafiati

Published: 4 June 2021

Last updated: 20 February 2023

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1

van der Schaft, Theo L., Wim C. de Bruijnz, Cornelia M. Mooy, and Paul T. V. M. de Jong. "Basal laminar deposit in the aging peripheral human retina." Graefe's Archive for Clinical and Experimental Ophthalmology 231, no. 8 (August 1993): 470–75. http://dx.doi.org/10.1007/bf02044234.

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van der Schaft, Theo L., Cornelia M. Mooy, Wim C. de Bruijn, Fred T. Bosman, and Paul T. V. M. de Jong. "Immunohistochemical light and electron microscopy of basal laminar deposit." Graefe's Archive for Clinical and Experimental Ophthalmology 232, no. 1 (January 1994): 40–46. http://dx.doi.org/10.1007/bf00176436.

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van der Schaft, Theo L. "Is Basal Laminar Deposit Unique for Age-Related Macular Degeneration?" Archives of Ophthalmology 109, no. 3 (March 1, 1991): 420. http://dx.doi.org/10.1001/archopht.1991.01080030122052.

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4

Lee, William R. "Is Basal Laminar Deposit Unique for Age-Related Macular Degeneration?" Archives of Ophthalmology 110, no. 1 (January 1, 1992): 15. http://dx.doi.org/10.1001/archopht.1992.01080130017009.

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Song, Delu, Imran Mohammed, Rupak Bhuyan, Takashi Miwa, Allison Lesher Williams, Damodar Gullipalli, Sayaka Sato, Ying Song, Joshua L. Dunaief, and Wen-Chao Song. "Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease." Investigative Opthalmology & Visual Science 59, no. 8 (July 10, 2018): 3405. http://dx.doi.org/10.1167/iovs.18-24133.

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6

van der Schaft, Theo L. "Is Basal Laminar Deposit Unique for Age-Related Macular Degeneration?-Reply." Archives of Ophthalmology 110, no. 1 (January 1, 1992): 16. http://dx.doi.org/10.1001/archopht.1992.01080130017010.

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7

Kliffen, M. "The APO*E3-Leiden mouse as an animal model for basal laminar deposit." British Journal of Ophthalmology 84, no. 12 (December 1, 2000): 1415–19. http://dx.doi.org/10.1136/bjo.84.12.1415.

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Toomey, Christopher B., Una Kelly, Daniel R. Saban, and Catherine Bowes Rickman. "Regulation of age-related macular degeneration-like pathology by complement factor H." Proceedings of the National Academy of Sciences 112, no. 23 (May 19, 2015): E3040—E3049. http://dx.doi.org/10.1073/pnas.1424391112.

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Complement factor H (CFH) is a major susceptibility gene for age-related macular degeneration (AMD); however, its impact on AMD pathobiology is unresolved. Here, the role of CFH in the development of AMD pathology in vivo was interrogated by analyzing aged Cfh+/− and Cfh−/− mice fed a high-fat, cholesterol-enriched diet. Strikingly, decreased levels of CFH led to increased sub-retinal pigmented epithelium (sub-RPE) deposit formation, specifically basal laminar deposits, following high-fat diet. Mechanistically, our data show that deposits are due to CFH competition for lipoprotein binding site

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Sura, Amol A., Ling Chen, Jeffrey D. Messinger, Thomas A. Swain, Gerald McGwin, K. Bailey Freund, and Christine A. Curcio. "Measuring the Contributions of Basal Laminar Deposit and Bruch's Membrane in Age-Related Macular Degeneration." Investigative Opthalmology & Visual Science 61, no. 13 (November 13, 2020): 19. http://dx.doi.org/10.1167/iovs.61.13.19.

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Sarks, Shirley, Svetlana Cherepanoff, Murray Killingsworth, and John Sarks. "Relationship of Basal Laminar Deposit and Membranous Debris to the Clinical Presentation of Early Age-Related Macular Degeneration." Investigative Opthalmology & Visual Science 48, no. 3 (March 1, 2007): 968. http://dx.doi.org/10.1167/iovs.06-0443.

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Espinosa-Heidmann, Diego G., John Sall, Eleut P. Hernandez, and Scott W. Cousins. "Basal Laminar Deposit Formation in APO B100 Transgenic Mice: Complex Interactions between Dietary Fat, Blue Light, and Vitamin E." Investigative Opthalmology & Visual Science 45, no. 1 (January 1, 2004): 260. http://dx.doi.org/10.1167/iovs.03-0910.

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Cousins, Scott W., Diego G. Espinosa-Heidmann, Anastasia Alexandridou, John Sall, Sander Dubovy, and Karl Csaky. "The Role of Aging, High Fat Diet and Blue Light Exposure in an Experimental Mouse Model for Basal Laminar Deposit Formation." Experimental Eye Research 75, no. 5 (November 2002): 543–53. http://dx.doi.org/10.1006/exer.2002.2047.

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13

Zarbin, M. A. "Age-Related Macular Degeneration: Review of Pathogenesis." European Journal of Ophthalmology 8, no. 4 (October 1998): 199–206. http://dx.doi.org/10.1177/112067219800800401.

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Age-related macular degeneration is a condition (a) characterized by accumulation of membranous debris on both sides of the retinal pigment epithelium (RPE) basement membrane. Clinical manifestations of drusen, atrophy of the RPE/choriocapillaris, RPE detachment, and choroidal new vessel (CNV) formation occur after age 50 years. A hypothetical pathogenic sequence of events consistent with known data is: 1) RPE dysfunction (e.g., precipitated by an inherited susceptibility and/or environmental exposure); 2) accumulation of intracellular material in the RPE (e.g., accumulation of normal substrat

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Kogaya, Y., S. Kim, S. Haruna, and T. Akisaka. "Heterogeneity of distribution pattern at the electron microscopic level of heparan sulfate in various basement membranes." Journal of Histochemistry & Cytochemistry 38, no. 10 (October 1990): 1459–67. http://dx.doi.org/10.1177/38.10.1698204.

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Using the high-iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining technique and enzymatic digestion, we investigated the ultrastructural distribution pattern of heparan sulfate side chains of heparan sulfate proteoglycan (HSPG) in various basement membranes (nerve, capillary, oral epithelial, muscle, and dental basement membranes). Four different distribution patterns of stain deposits were identified as heparan sulfate on the basis of enzymatic degradation by heparitinase. In some basement membranes associated with tooth germs and oral epithelium, HID-TCH-SP stain deposit

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15

Aplin, J. D., S. Campbell, and T. D. Allen. "The extracellular matrix of human amniotic epithelium: ultrastructure, composition and deposition." Journal of Cell Science 79, no. 1 (November 1, 1985): 119–36. http://dx.doi.org/10.1242/jcs.79.1.119.

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Ultrastructural comparisons have been made between human amnion extracellular matrix in tissue and cell culture. Immunochemical analysis of matrix deposited by monolayers of cultured amnion epithelial cells has also been undertaken. The basal cell surfaces are highly invaginated with an associated basal lamina that is more electron dense at the distal tips of basal cell processes where hemidesmosomes are frequent. Immediately below the lamina densa is a zone rich in collagen bundles. In the underlying stroma two types of fibril predominate, one striated of 50 nm diameter and one of 18 nm diame

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Notomi, Shoji, Kenji Ishihara, Nikolaos E. Efstathiou, Jong-Jer Lee, Toshio Hisatomi, Takashi Tachibana, Eleni K. Konstantinou, et al. "Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina." Proceedings of the National Academy of Sciences 116, no. 47 (November 7, 2019): 23724–34. http://dx.doi.org/10.1073/pnas.1906643116.

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The early stages of age-related macular degeneration (AMD) are characterized by the accumulation of basal laminar deposits (BLamDs). The mechanism for BLamDs accumulating between the retinal pigment epithelium (RPE) and its basal lamina remains elusive. Here we examined the role in AMD of lysosome-associated membrane protein-2 (LAMP2), a glycoprotein that plays a critical role in lysosomal biogenesis and maturation of autophagosomes/phagosomes. LAMP2 was preferentially expressed by RPE cells, and its expression declined with age. Deletion of the Lamp2 gene in mice resulted in age-dependent aut

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Kogaya, Y., and K. Furuhashi. "Ultrastructural distribution of sulfated glycosaminoglycans in epithelial-mesenchymal interface of developing rat tooth germs." Journal of Histochemistry & Cytochemistry 35, no. 5 (May 1987): 585–93. http://dx.doi.org/10.1177/35.5.2435784.

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We investigated the ultrastructural distribution of sulfated glycosaminoglycans in the epithelial-mesenchymal interface of tooth germs by use of the high-iron diamine thiocarbohydrazide silver proteinate (HID-TCH-SP) staining and enzymatic digestion method. At an early stage in odontoblast differentiation, HID-TCH-SP stain deposits were sparsely distributed in the basement membrane and in the intercellular spaces. Subsequently, as formation of the initial predentin matrix began, HID-TCH-SP stain deposits were densely distributed in the interfibrillar spaces and the basement membrane. Testicula

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18

de Guzman, Roche C., Jeffrey A. Loeb, and Pamela J. VandeVord. "Electrospinning of Matrigel to Deposit a Basal Lamina-Like Nanofiber Surface." Journal of Biomaterials Science, Polymer Edition 21, no. 8-9 (January 1, 2010): 1081–101. http://dx.doi.org/10.1080/09205063.2010.11964027.

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de Guzman, Roche C., Jeffrey A. Loeb, and Pamela J. VandeVord. "Electrospinning of Matrigel to Deposit a Basal Lamina-Like Nanofiber Surface." Journal of Biomaterials Science, Polymer Edition 21, no. 8 (May 1, 2010): 1081–101. http://dx.doi.org/10.1163/092050609x12457428936116.

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20

Cousins, Scott W., Diego G. Espinosa-Heidmann, Anastasia Alexandridou, John Sall, Sander Dubovy, and Karl Csaky. "Erratum to “The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation” by S.W. Cousins, D.G. Espinosa-Heidmann, A. Alexandridou, J. Sall, S. Dubovy and K. Csaky [Experimental Eye Research 75 (2002) 543–553]." Experimental Eye Research 76, no. 4 (April 2003): 517. http://dx.doi.org/10.1016/s0014-4835(03)00025-3.

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21

Anglister, L., and U. J. McMahan. "Basal lamina directs acetylcholinesterase accumulation at synaptic sites in regenerating muscle." Journal of Cell Biology 101, no. 3 (September 1, 1985): 735–43. http://dx.doi.org/10.1083/jcb.101.3.735.

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In skeletal muscles that have been damaged in ways which spare the basal lamina sheaths of the muscle fibers, new myofibers develop within the sheaths and neuromuscular junctions form at the original synaptic sites on them. At the regenerated neuromuscular junctions, as at the original ones, the muscle fibers are characterized by junctional folds and accumulations of acetylcholine receptors and acetylcholinesterase (AChE). The formation of junctional folds and the accumulation of acetylcholine receptors is known to be directed by components of the synaptic portion of the myofiber basal lamina.

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22

Reale, Enrico, Stephanie Groos, Ute Eckardt, Claus Eckardt, and Liliana Luciano. "New Components of ‘Basal Laminar Deposits’ in Age-Related Macular Degeneration." Cells Tissues Organs 190, no. 3 (2009): 170–81. http://dx.doi.org/10.1159/000187632.

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23

Anderson, M. J. "Nerve-induced remodeling of muscle basal lamina during synaptogenesis." Journal of Cell Biology 102, no. 3 (March 1, 1986): 863–77. http://dx.doi.org/10.1083/jcb.102.3.863.

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To identify mechanisms that regulate the deposition of the junctional basal lamina during synaptogenesis, immunocytochemical experiments were carried out on cultured nerve and muscle cells derived from Xenopus laevis embryos. In some experiments successive observations were made on individual muscle cells after pulse-labeling with a fluorescent monoclonal antibody specific for a basal lamina proteoglycan. In others, old and new proteoglycan molecules were differentially labeled with antibody conjugated to contrasting fluorochromes. These observations revealed that surface deposits of antibody-

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24

Lommatzsch, Albrecht, Pia Hermans, Bernhard Weber, and Daniel Pauleikhoff. "Complement factor H variant Y402H and basal laminar deposits in exudative age-related macular degeneration." Graefe's Archive for Clinical and Experimental Ophthalmology 245, no. 11 (August 18, 2007): 1713–16. http://dx.doi.org/10.1007/s00417-007-0649-7.

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25

Yde, Jacob C., N. Tvis Knudsen, Nicolaj K. Larsen, Christian Kronborg, Ole B. Nielsen, Jan Heinemeier, and Jesper Olsen. "The presence of thrust-block naled after a major surge event: Kuannersuit Glacier, West Greenland." Annals of Glaciology 42 (2005): 145–50. http://dx.doi.org/10.3189/172756405781812907.

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AbstractThrust-block naled in front of Kuannersuit Glacier, West Greenland, appears to have formed during the termination of a terrestrial surge event by a combination of enhanced winter runoff, rapid advance of the glacier terminus, and proglacial stress release by thrusting and stacking of naled blocks. This process is equivalent to the formation of thrust-block moraines. The thrust-block naled consists of at least seven thrust sheets, which are characterized by stratified ice with beds composed of a lower debris-rich lamina, an intermediate dispersed lamina and a top clean-ice lamina, and u

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Empeslidis, T., U. Imrani, A. Vardarinos, N. Menassa, and S. Banerjee. "Spontaneous Resolution of Retinal Pigment Epithelial Detachments and Visual Improvement in Patient with MPGN II: A Case Report." Case Reports in Ophthalmological Medicine 2012 (2012): 1–4. http://dx.doi.org/10.1155/2012/864198.

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A 31-year-old female suffering from membranoproliferative glomerulonephritis type II (MPGN II) presented to the Eye Casualty Department reporting a history of blurred and distorted vision. The patient appeared to have drusenoid retinal epithelial detachments and minimal intraretinal fluid. The subretinal deposits, basal lamina drusen, and pigment epithelial detachment appeared to resemble a “stars in the sky” picture with no symmetry between the eyes. The retinal pigment epithelial detachments improved and flattened over 18 month. and the best corrected visual acuity improved in the most affec

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Kamyshanskiy, Yevgeniy, Olga Kostyleva, Maida Tussupbekova, Leila Stabayeva, Gulnazira Imanbayeva, Raihan Nygyzbayeva, Evgeniy Kotov та Denis Kossitsyn. "Аllergic Basal Deciduitis as a Reason of Recurrent Antenatal Fetal Death". Open Access Macedonian Journal of Medical Sciences 9, № C (26 червня 2021): 80–83. http://dx.doi.org/10.3889/oamjms.2021.6129.

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BACKGROUND: Allergic diseases of pregnant women are associated with chronic placental insufficiency and the development of immunopathological conditions of unknown etiology in a child in postnatal life. Pregnancy with bronchial asthma is often complicated by intrauterine growth retardation, preeclampsia, and antenatal fetal death. AIM: The objective was to present a clinical case of recurrent antenatal fetal death in the third trimester in women with bronchial asthma under controlled course. CASE REPORT: Pregnancy proceeded without clinical signs of exacerbation of bronchial asthma and allergi

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Bendella, Mohamed, Madani Benyoucef, Amine Cherif, and Miloud Benhamou. "Ichnology and sedimentology of the “Argiles de Saïda” formation (Callovo-Oxfordian) of the Djebel Brame (Tiaret, Algeria)." Bulletin de la Société Géologique de France 182, no. 5 (September 1, 2011): 417–25. http://dx.doi.org/10.2113/gssgfbull.182.5.417.

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Abstract The focus of this note is an ichnological study of the “Argiles de Saïda” formation (Callovo-Oxfordian) in the Djebel Brame, a region representing the eastern extremity of the Tlemcenian domain and marked by rhythmic clay-sandstone sedimentation. From a lithostratigraphic viewpoint, the formation is composed of two units with a distinct sequential organization and trace fossil content. These deposits are characterized by weak to moderate bioturbation, eleven ichnogenera were found: Bergaueria, Chondrites, Diplichnites, Megagrapton, Neonereites, Nereites, Ophiomorpha, Palaeophycus, Rh

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da Cruz-Landim, Carminda, and Silvana Beani Poiani. "Cephalic salivary gland ultrastructure of worker and queen eusocial bees (Hymenoptera, Apidae)." Animal Biology 59, no. 3 (2009): 299–311. http://dx.doi.org/10.1163/157075609x454935.

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AbstractEusocial bees present a pair of functional salivary glands in head, the cephalic salivary glands. These glands from workers and queens of two eusocial bee species, Apis mellifera and Scaptotrigona postica, were examined at different life stages using routine transmission electron microscopy techniques to correlate morphology and gland functions. Ultrastructural features of worker and queen glands ducts and secretory units were descriptively compared between species. The duct cells present basal plasma membrane invaginations reaching the apical region. Intercellular space and invaginati

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Beaudry, Luc M., and Gilbert Prichonnet. "Formation of De Geer Moraines Deposited Subglacially, Central Québec." Géographie physique et Quaternaire 49, no. 3 (November 30, 2007): 337–61. http://dx.doi.org/10.7202/033059ar.

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ABSTRACT This paper presents a model for the genesis of De Geer moraines in the Chapais and Radisson areas, Québec. The model is mainly based on faciès and deformation structure analysis. Three facies associations have been identified: (1) sorted sediments that form foreset laminations dipping downglacier. Till lenses or glacial diamictons are found within the sorted sediments or form a surficial layer on the proximal side of the sections; (2) a non-fissile and poorly compacted till overlies and deforms sorted sediments. Laminae of finely sorted sediments may be incorporated in the till; (3) a

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Schneider, Jay A., and Joseph G. Carter. "Evolution and phylogenetic significance of cardioidean shell microstructure (Mollusca, Bivalvia)." Journal of Paleontology 75, no. 3 (May 2001): 607–43. http://dx.doi.org/10.1017/s002233600003969x.

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The shell microstructure of Carboniferous and Triassic permophorids; Triassic and Recent carditids; Devonian, Carboniferous, and Triassic crassatelloideans; and Jurassic through Recent cardioideans is examined in a phylogenetic context, using separate microstructural and morphologic data sets, as well as a combined data set. The microstructural and morphologic data sets are significantly incongruent, but the combined data set suggests that modiomorphoideans (modiomorphids and permophorids) are basal to crassatelloideans; crassatelloideans are basal to carditids (includingSeptocardia), and card

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Ackerman, Jeanne, Erick F. Gonzalez, and Enid Gilbert-Barness. "Immunological Studies of the Placenta in Maternal Connective Tissue Disease." Pediatric and Developmental Pathology 2, no. 1 (January 1999): 19–24. http://dx.doi.org/10.1007/s100249900085.

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Maternal connective tissue disease is an important cause of second-trimester fetal loss. In order to assess the pathological changes in the placenta in maternal connective tissue disease, we reviewed the clinical histories and performed histologic and immunofluorescence studies on nine placentas: five from mothers with systemic lupus erythematosus (SLE), two from mothers with mixed connective tissue disease (MCTD), one from a mother with rheumatoid arthritis (RA), and one from a mother without prior known connective tissue disease. Excessive intervillous fibrin deposition and infarction were n

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Baas, Jaco H., Niall D. Tracey, and Jeff Peakall. "Sole marks reveal deep-marine depositional process and environment: Implications for flow transformation and hybrid-event-bed models." Journal of Sedimentary Research 91, no. 9 (September 30, 2021): 986–1009. http://dx.doi.org/10.2110/jsr.2020.104.

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ABSTRACT Deposits of sediment gravity flows in the Aberystwyth Grits Group (Silurian, west Wales, United Kingdom) display evidence that sole marks are suitable for reconstructing depositional processes and environments in deep-marine sedimentary successions. Based on drone imagery, 3D laser scanning, high-resolution sedimentary logging, and detailed descriptions of sole marks, an outcrop 1600 m long between the villages of Aberarth and Llannon was subdivided into seven lithological units, representing: a) mudstone-poor, coarse-grained and thick-bedded submarine channel fills, dominated by the

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Baas, Jaco H., Niall D. Tracey, and Jeff Peakall. "Sole marks reveal deep-marine depositional process and environment: Implications for flow transformation and hybrid-event-bed models." Journal of Sedimentary Research 91, no. 9 (September 30, 2021): 986–1009. http://dx.doi.org/10.2110/jsr.2020.104.

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ABSTRACT Deposits of sediment gravity flows in the Aberystwyth Grits Group (Silurian, west Wales, United Kingdom) display evidence that sole marks are suitable for reconstructing depositional processes and environments in deep-marine sedimentary successions. Based on drone imagery, 3D laser scanning, high-resolution sedimentary logging, and detailed descriptions of sole marks, an outcrop 1600 m long between the villages of Aberarth and Llannon was subdivided into seven lithological units, representing: a) mudstone-poor, coarse-grained and thick-bedded submarine channel fills, dominated by the

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Lackovic, Maja, Aleksandar Damjanovic, Maja Ivkovic, Maja Pantovic, Milos Bajcetic, Branislav Rovcanin, Aleksandra Pavlovic, Nadezda Sternic, and Miroslava Jasovic-Gasic. "Depression in CADASIL patients." Archives of Biological Sciences 66, no. 3 (2014): 1187–94. http://dx.doi.org/10.2298/abs1403187l.

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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary neurological disease accompanied by recurrent ischemic events, characterized by the presence of psychiatric disorders. The aim of this study was to examine the occurrence of depression and its severity among patients with CADASIL. Sixteen patients with diffuse white matter changes on MRI and clinical signs suggesting CADASIL were included in the study. Definitive diagnosis of CADASIL was obtained by electron microscopic analysis of skin biopsies. Testing of the patients? affecti

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Ballan-Dufrançais, C., A. Y. Jeantet, A. Geffard, J. C. Amiard, and C. Amiard-Triquet. "Cellular and tissular distribution of copper in an intrasedimentary bivalve, the Baltic clam Macoma balthica, originating from a clean or a metal-rich site." Canadian Journal of Fisheries and Aquatic Sciences 58, no. 10 (October 1, 2001): 1964–74. http://dx.doi.org/10.1139/f01-129.

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Baltic clams (Macoma balthica) from clean and industrialized areas were exposed to 30 ng Cu·mL1 or 40 ng Cu·mL1 for 13 days. Specimens from the industrialized site accumulated less Cu in their soft tissues, suggesting that those clams living in a metal-rich area are able to limit metal accumulation. Cu and metallothionein-like protein (MTLP) levels were positively correlated in specimens from the industrialized site only, indicating that perhaps living in a polluted area enables them to use this method of detoxification. The contaminated specimens contained Cu-rich microgranules in the basal

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Rizzo, Vincenzo, and Nicola Cantasano. "Possible organosedimentary structures on Mars." International Journal of Astrobiology 8, no. 4 (August 28, 2009): 267–80. http://dx.doi.org/10.1017/s1473550409990152.

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AbstractThis study, using the Microscopic Imager (MI) of NASA Rover Exploration Mission's (REM) ‘Opportunity’, aims to explain the origin of laminated sediments lying at Meridiani Planum of Mars, and of the strange spherules, known as blueberries, about which several hypotheses have been formulated. To this purpose, images of the sedimentary textures of layers and fragments captured by REM have been analysed; sediments that NASA has already established as ‘pertinent to water presence’. Our study shows that such laminated sediments and the spherules they contain could be organosedimentary struc

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Fernández-Robredo, Patricia, Luis M. Sádaba, Angel Salinas-Alamán, Sergio Recalde, José A. Rodríguez, and Alfredo García-Layana. "Effect of Lutein and Antioxidant Supplementation on VEGF Expression, MMP-2 Activity, and Ultrastructural Alterations in Apolipoprotein E-Deficient Mouse." Oxidative Medicine and Cellular Longevity 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/213505.

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Oxidative stress is involved in the pathogenesis of several diseases such as atherosclerosis and age-related macular degeneration (AMD). ApoE-deficient mice (apoE−/−) are a well-established model of genetic hypercholesterolemia and develop retinal alterations similar to those found in humans with AMD. Thus supplementation with lutein or multivitamin plus lutein and glutathione complex (MV) could prevent the onset of these alterations. ApoE−/−mice (n=40, 3 months old) were treated daily for 3 months with lutein (AE-LUT) or MV (two doses): AE-MV15 (15 mg/kg/day) and AE-MV50 (50 mg/kg/day) and we

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Koski, Randolph A. "Ferromanganese deposits from the Gulf of Alaska Seamount Province: mineralogy, chemistry, and origin." Canadian Journal of Earth Sciences 25, no. 1 (January 1, 1988): 116–33. http://dx.doi.org/10.1139/e88-012.

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Ferromanganese-oxide deposits dredged from four seamounts (Welker, Miller, Murray, and Patton) in the Gulf of Alaska Seamount Province include poorly crystallized microlaminated crusts on basalt substrate, well-crystallized Mn-oxide veins in epiclastic sedimentary rocks, and crystalline Mn-oxide layers and micronodules in phosphorite. The principal rock types dredged are alkali-basalt pillow fragments and tuffaceous conglomerate and sandstone. The glassy rims of pillow fragments, the glassy goundmass of large volcanic clasts, and the tuffaceous component of the sediment are altered to palagoni

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Molén, Mats O. "Field evidence suggests that the Palaeoproterozoic Gowganda Formation in Canada is non-glacial in origin." Geologos 27, no. 2 (August 1, 2021): 73–91. http://dx.doi.org/10.2478/logos-2021-0009.

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Abstract During more than a century since its original identification, the Gowganda Formation in Ontario (Canada) has gradually been reinterpreted from representing mainly subglacial tillites to secondary gravity flow and glaciomarine deposits. The main pieces of geological evidence advanced in favour of glaciation in recent articles are outsized clasts that have been interpreted as dropstones and patches of diamictites in a single small-sized area at Cobalt which is still interpreted as displaying subglacial basal tillites. The present research considers field evidence in the Gowganda Formati

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Crino, Peter B., Barry Greenberg, John A. Martin, Virginia M. Y. Lee, William D. Hill та John Q. Trojanowski. "β-Amyloid Peptide and Amyloid Precursor Proteins in Olfactory Mucosa of Patients with Alzheimer's Disease, Parkinson's Disease, and down Syndrome". Annals of Otology, Rhinology & Laryngology 104, № 8 (серпень 1995): 655–61. http://dx.doi.org/10.1177/000348949510400812.

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Dystrophic neurites are present in olfactory epithelium (OE) of patients with Alzheimer's disease (AD), Parkinson's disease (PD), and Down syndrome (DS) and occasionally in normal individuals. Cultured olfactory neuroblasts from AD patients generate carboxy terminal amyloid precursor protein (APP) fragments that contain β-amyloid (Aβ), but it is not known if deposits of Aβ and/or APP fragments occur in the OE of individuals with or without AD, PD, or DS. To determine if Aβ accumulates in the OE in situ, we probed postmortem samples of olfactory mucosa from patients with AD, PD and AD (PD/AD),

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Tan, Anna C. S., Matthew G. Pilgrim, Sarah Fearn, Sergio Bertazzo, Elena Tsolaki, Alexander P. Morrell, Miaoling Li, et al. "Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration." Science Translational Medicine 10, no. 466 (November 7, 2018): eaat4544. http://dx.doi.org/10.1126/scitranslmed.aat4544.

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Drusen are lipid-, mineral-, and protein-containing extracellular deposits that accumulate between the basal lamina of the retinal pigment epithelium (RPE) and Bruch’s membrane (BrM) of the human eye. They are a defining feature of age-related macular degeneration (AMD), a common sight-threatening disease of older adults. The appearance of heterogeneous internal reflectivity within drusen (HIRD) on optical coherence tomography (OCT) images has been suggested to indicate an increased risk of progression to advanced AMD. Here, in a cohort of patients with AMD and drusen, we show that HIRD indica

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Feliciani, Claudio, Saman Mohammad Pour, Paola Toto, Giulia Coscione, Paolo Amerio, and Pierluigi Amerio. "Direct Immunofluorescence Diagnosis of Pemphigus without Biopsy." Journal of Cutaneous Medicine and Surgery 2, no. 4 (April 1998): 209–11. http://dx.doi.org/10.1177/120347549800200406.

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Background: Direct immunofluorescence (DIF) is a necessary examination tool for the diagnosis of pemphigus. The suction-blister-method splits the skin at the lamina lucida and it is possible with a scalpel to separate the entire epidermis from the dermis. Objective: The study was to determine whether DIF is reliable on epidermal sheets separated using a suction apparatus. Methods: Thirteen patients were selected for this study: (nine with pemphigus vulgaris (PV), one with paraneoplastic pemphigus (PP), and three with pemphigus erythematosus (PE). Frozen epidermal sheets, separated from the der

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Douillet, G. A., B. Taisne, È. Tsang-Hin-Sun, S. K. Müller, U. Kueppers, and D. B. Dingwell. "Syn-eruptive, soft-sediment deformation of deposits from dilute pyroclastic density current: triggers from granular shear, dynamic pore pressure, ballistic impacts and shock waves." Solid Earth 6, no. 2 (May 21, 2015): 553–72. http://dx.doi.org/10.5194/se-6-553-2015.

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Abstract. Soft-sediment deformation structures can provide valuable information about the conditions of parent flows, the sediment state and the surrounding environment. Here, examples of soft-sediment deformation in deposits of dilute pyroclastic density currents are documented and possible syn-eruptive triggers suggested. Outcrops from six different volcanoes have been compiled in order to provide a broad perspective on the variety of structures: Soufrière Hills (Montserrat), Tungurahua (Ecuador), Ubehebe craters (USA), Laacher See (Germany), and Tower Hill and Purrumbete lakes (both Austral

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Landowski, Michael, Una Kelly, Mikael Klingeborn, Marybeth Groelle, Jin-Dong Ding, Daniel Grigsby, and Catherine Bowes Rickman. "Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice." Proceedings of the National Academy of Sciences 116, no. 9 (February 11, 2019): 3703–11. http://dx.doi.org/10.1073/pnas.1814014116.

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One of the strongest susceptibility genes for age-related macular degeneration (AMD) is complement factor H (CFH); however, its impact on AMD pathobiology remains unresolved. Here, the effect of the principal AMD-risk–associated CFH variant (Y402H) on the development and progression of age-dependent AMD-like pathologies was determined in vivo. Transgenic mice expressing equal amounts of the full-length normal human CFH Y402 (CFH-Y/0) or the AMD-risk associated CFH H402 (CFH-H/H) variant on a Cfh−/− background were aged to 90 weeks and switched from normal diet (ND) to a high fat, cholesterol-e

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Stevenson, Christopher J., Jeff Peakall, David M. Hodgson, Daniel Bell, and Aurélia Privat. "TB or not TB: banding in turbidite sandstones." Journal of Sedimentary Research 90, no. 8 (August 19, 2020): 821–42. http://dx.doi.org/10.2110/jsr.2020.43.

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ABSTRACT Recognition and interpretation of sedimentary structures is fundamental to understanding sedimentary processes. Banded sandstones are an enigmatic sedimentary facies comprising alternating mud-rich (as matrix and/or mud clasts) and cleaner sand layers. The juxtaposition of hydrodynamically different grain sizes contradicts established models of cleaner-sand bedform development. Here, outcrop, subsurface core, and petrographic data from three deep-water systems, with well-constrained paleogeographic contexts, are used to describe the range of sedimentary textures, bedform morphologies,

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Holwerda, Femke M., Mark Evans, and Jeff J. Liston. "Additional sauropod dinosaur material from the Callovian Oxford Clay Formation, Peterborough, UK: evidence for higher sauropod diversity." PeerJ 7 (February 14, 2019): e6404. http://dx.doi.org/10.7717/peerj.6404.

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Four isolated sauropod axial elements from the Oxford Clay Formation (Callovian, Middle Jurassic) of Peterborough, UK, are described. Two associated posterior dorsal vertebrae show a dorsoventrally elongated centrum and short neural arch, and nutrient or pneumatic foramina, most likely belonging to a non-neosauropod eusauropod, but showing ambiguous non-neosauropod eusauropod and neosauropod affinities. An isolated anterior caudal vertebra displays a ventral keel, a ‘shoulder’ indicating a wing-like transverse process, along with a possible prespinal lamina. This, together with an overall high

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Fragiotta, Serena, Mariacristina Parravano, Riccardo Sacconi, Eliana Costanzo, Daniele De Geronimo, Francesco Prascina, Vittorio Capuano, et al. "Sub-retinal pigment epithelium tubules in non-neovascular age-related macular degeneration." Scientific Reports 12, no. 1 (September 7, 2022). http://dx.doi.org/10.1038/s41598-022-19193-6.

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AbstractTo describe a novel optical coherence tomography (OCT) signature resembling sub-retinal pigment epithelium (RPE) tubules (SRT) in non-neovascular age-related macular degeneration (AMD). Patients suffering from non-neovascular AMD with complete medical records and multimodal imaging were retrospectively revised in three different tertiary care centers. Multimodal imaging included color fundus photograph, spectral-domain OCT (Spectralis, Heidelberg Engineering, Germany), fundus autofluorescence, OCT angiography (RTVue XR Avanti, Optovue, Inc., Fremont, CA). A total of 7 eyes of 7 patient

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Fragiotta, Serena, Mariacristina Parravano, Riccardo Sacconi, Eliana Costanzo, Pasquale Viggiano, Francesco Prascina, Vittorio Capuano, Eric H. Souied, and Giuseppe Querques. "A common finding in foveal-sparing extensive macular atrophy with pseudodrusen (EMAP) implicates basal laminar deposits." Retina Publish Ahead of Print (February 21, 2022). http://dx.doi.org/10.1097/iae.0000000000003463.

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Aghighi, Maryam, David Chercover, and Maral Rahvar. "Collision Cutaneous Neoplasms Consisting of Melanoma and Basal Cell Carcinoma." Dermatology Practical & Conceptual, July 8, 2021, 2021037. http://dx.doi.org/10.5826/dpc.1103a37.

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Collision tumors are defined as two histologically different tumor types that arise at the same anatomical location. According to the literature review performed, there are reports of 27 cases of collision tumors involving lentigo maligna melanoma (LMM) in-situ and basal cell carcinoma (BCC). In the absence of melanocytic extension beyond the lamina propria of the BCC compartment, mixed tumors are considered as melanoma in-situ colonizing the BCC, rather than invasive melanomas. We report an uncommon case of collision of BCC with LMM, two primary skin tumors that are seen in patients with sign

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