Log in

Relevant bibliographies by topics / Basic amino acids / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Basic amino acids.

Dissertations / Theses on the topic 'Basic amino acids'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 40 dissertations / theses for your research on the topic 'Basic amino acids.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Ye, Shijie [Verfasser]. "Site-specific incorporation of fluorinated amino acids into basic pancreatic trypsin inhibitor / Shijie Ye." Berlin : Freie Universität Berlin, 2014. http://d-nb.info/1052893961/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Hatanaka, Takahiro. "Studies of transport of neutral/basic amino acids and amino acid-derivative drugs using intestinal brush border membrane vesicles and the ATB[0,+] clone." Kyoto University, 2002. http://hdl.handle.net/2433/149524.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Seid, Tahir Seid Hosen. "COMPARATIVE STUDY OF HYDROLYSIS PERFORMED WITH MODERN MICROWAVE TECHNIQUE AND THE TRADITIONAL METHOD." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-174668.

Full text

Abstract:

Proteins are vital to all cells in the body. They consist of long chains of amino acids. To be able to study the amino acid composition of a protein it is necessary to hydrolyse it, followed by separation and quantification. When the protein is hydrolysed, in this case ß-lactoglobulin, the protein is divided into individual amino acids. The method that traditionally has been used to hydrolyse proteins takes 24-72 hours to complete. Recently a new microwave heating technique was introduced. With the Ethos1 microwave oven it takes less than one hour to hydrolyse proteins. The objective of this s

APA, Harvard, Vancouver, ISO, and other styles

4

Cao, Haibo. "Protein Structure Recognition From Eigenvector Analysis to Structural Threading Method." Washington, D.C. : Oak Ridge, Tenn. : United States. Dept. of Energy. Office of Science ; distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2003. http://www.osti.gov/servlets/purl/822060-2L2Xvm/native/.

Full text

Abstract:

Thesis (Ph.D.); Submitted to Iowa State Univ., Ames, IA (US); 12 Dec 2003.<br>Published through the Information Bridge: DOE Scientific and Technical Information. "IS-T 2028" Haibo Cao. 12/12/2003. Report is also available in paper and microfiche from NTIS.

APA, Harvard, Vancouver, ISO, and other styles

5

Harnevik, Lotta. "Molecular genetic studies on cystinuria." Doctoral thesis, Linköping : Univ, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med1034s.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Grove, Christian A. "A Multiparameter Network Reveals Extensive Divergence Between C. elegans bHLH Transcription Factors: A Dissertation." eScholarship@UMMS, 2009. https://escholarship.umassmed.edu/gsbs_diss/441.

Full text

Abstract:

It has become increasingly clear that transcription factors (TFs) play crucial roles in the development and day-to-day homeostasis that all biological systems experience. TFs target particular genes in a genome, at the appropriate place and time, to regulate their expression so as to elicit the most appropriate biological response from a cell or multicellular organism. TFs can often be grouped into families based on the presence of similar DNA binding domains, and these families are believed to have expanded and diverged throughout evolution by several rounds of gene duplication and mutation.

APA, Harvard, Vancouver, ISO, and other styles

7

Desai, Meera Jay. "Development of Chiral LC-MS Methods for small Molecules and Their Applications in the Analysis of Enantiomeric Composition and Pharmacokinetic Studies." Ames, Iowa : Oak Ridge, Tenn. : Ames Laboratory ; distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 2004. http://www.osti.gov/servlets/purl/837266-GaBf1y/webviewable/.

Full text

Abstract:

Thesis (Ph.D.); Submitted to Iowa State Univ., Ames, IA (US); 19 Dec 2004.<br>Published through the Information Bridge: DOE Scientific and Technical Information. "IS-T 2134" Meera Jay Desai. US Department of Energy 12/19/2004. Report is also available in paper and microfiche from NTIS.

APA, Harvard, Vancouver, ISO, and other styles

8

Xie, Jenny X. "Regulation of BACH1/FANCJ Function in DNA Damage Repair: A Dissertation." eScholarship@UMMS, 2009. https://escholarship.umassmed.edu/gsbs_diss/435.

Full text

Abstract:

The DNA damage response (DDR) pathway is a complicated network of interacting proteins that function to sense and remove DNA damage. Upon exposure to DNA damage, a signaling cascade is generated. The damage is either removed, restoring the original genetic sequence, or apoptosis is activated. In the absence of DDR, cells are unable to effectively process DNA damage. Unprocessed DNA damage can lead to chromosomal changes, gene mutations, and malignant transformation. Thus, the proteins involved in DDR are critical for maintaining genomic stability. One essential DDR protein is the BRCA1 Associa

APA, Harvard, Vancouver, ISO, and other styles

9

Dupuis, Lucie. "Molecular basis of biotin-responsive multiple carboxylase deficiency." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=27309.

Full text

Abstract:

Multiple carboxylase deficiency (MCD) results from a decreased activity of holocarboxylase synthetase (HCS) which is responsible for the biotinylation of the four biotin-dependent carboxylases found in humans. The disease can be treated with pharmacologic doses of oral biotin (biotin-responsiveness). The cDNA for HCS contains a biotin-binding domain deduced by analogy with the sequence and crystal structure of the E. coli BirA biotin ligase. E. coli birA$ sp-$ mutations causing biotin-auxotrophy all localize to this region. Of six point mutations I have identified in MCD patients, four localiz

APA, Harvard, Vancouver, ISO, and other styles

10

Khalil, Talat tariq. "Protons and X-ray damaging effects on DNA self-assembled on Mylar foils and in solution in absence and in the presence of gold nanoparticles." Thesis, Besançon, 2016. http://www.theses.fr/2016BESA2070/document.

Full text

Abstract:

Cette thèse vise à étudier les nanoparticules d'or (NPOs) comme radio sensibilisateur et nano catalyseur afin d'améliorer la production d'espèces réactives de l'oxygène (EROS) et à fournir un aperçu de l'effet protecteur potentiel des acides aminés de base contre les effets des rayonnements ionisants afin d'étudier le mécanisme de dommages de l'ADN. En outre, il vise à améliorer notre connaissance des effets directs et indirects sur l'ADN plasmatique qui est une cible importante et sensible lors de l'étude des effets des rayonnements ionisants. Cette étude nécessite à la fois Ia bonne distribu

APA, Harvard, Vancouver, ISO, and other styles

11

Bigelow, Jeffrey. "Quaternary Amino Acid Geochronology of the Lahontan Basin, Nevada, and the Chewaucan Basin, Oregon." DigitalCommons@USU, 1998. https://digitalcommons.usu.edu/etd/3587.

Full text

Abstract:

Amino acid geochronology based on fossil molluscs provides a useful approach to determining the Quaternary history of Great Basin lakes. The Lahontan basin, Nevada, and the Chewaucan basin, Oregon, in the northwest corner of the Great Basin, both contained lakes during the Quaternary. The aim of this study is to improve the Quaternary geochronology in these two basins by measuring time-dependent changes in amino acids preserved in fossil molluscan shells. The abundance of D-alloisoleucine relative to Lisoleucine (All) characterizes the extent of racemization, which increases with age and Ul fo

APA, Harvard, Vancouver, ISO, and other styles

12

Yu, Elizabeth A. "Investigating Age-Dependent Arthropathy in a Circadian Mutant Mouse Model: A Dissertation." eScholarship@UMMS, 2011. https://escholarship.umassmed.edu/gsbs_diss/544.

Full text

Abstract:

Ectopic calcification can cause pain and limit mobility. Studies suggest that circadian genes may play a role in the calcification process. Core circadian genes Clock, Npas2, and Bmal1 are transcription factors that form CLOCK:BMAL1 or NPAS2:BMAL1 transactivator complexes that drive the rhythmic expression of circadian oscillator genes and output genes. Circadian oscillator genes Period1-3 and Cryptochrome1-2 encode proteins that form transcription repressor complexes that feedback to inhibit CLOCK/NPAS2:BMAL1 activity, thus completing the feedback loop that is the basis of the molecular circa

APA, Harvard, Vancouver, ISO, and other styles

13

Zhao, Yu. "Amino acid-derived Lewis basic catalysts for asymmetric allylation of aldehydes and silylation of alcohols." Thesis, Boston College, 2008. http://hdl.handle.net/2345/357.

Full text

Abstract:

Thesis advisor: Marc L. Snapper<br>Chapter 1. Review of concept and methodology development for asymmetric allylation of carbonyls and imines. Chapter 2. Description of the catalytic asymmetric addition of allyltrichlorosilane to aldehydes catalyzed by a proline-based N-oxide catalyst. Chapter 3. Introduction of the first catalytic asymmetric silylation of alcohols for desymmetrization of meso-diols. Chapter 4. Presentation of asymmetric silylation for synthesis of chiral syn-1,2-diols by kinetic resolution or divergent reaction on a racemic mixture<br>Thesis (PhD) — Boston College, 2008<br>Su

APA, Harvard, Vancouver, ISO, and other styles

14

Litman, Rachel. "Characterization of the BACH1 Helicase in the DNA Damage Response Pathway: a Dissertation." eScholarship@UMMS, 2007. https://escholarship.umassmed.edu/gsbs_diss/329.

Full text

Abstract:

DNA damage response pathways are a complicated network of proteins that function to remove and/or reverse DNA damage. Following genetic insult, a signal cascade is generated, which alerts the cell to the presence of damaged DNA. Once recognized, the damage is either removed or the damaged region is excised, and the original genetic sequence is restored. However, when these pathways are defective the cell is unable to effectively mediate the DNA damage response and the damage persists unrepaired. Thus, the proteins that maintain the DNA damage response pathway are critical in preserving genomic

APA, Harvard, Vancouver, ISO, and other styles

15

Artschwager, Raik. "Basic side chain containing amino acid derived peptido sulfonyl fluorides : an approach to future β2 selective proteasome inhibitors". Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8534/.

Full text

Abstract:

Peptido sulfonyl fluorides are a relatively new class of protease inhibitors which have undergone considerable development in recent years. Due to the right balance of reactivity and chemical stability, the sulfonyl fluoride moiety is denoted as a “privileged warhead” in chemical biology nowadays. This thesis describes the development of basic side chain containing amino acid derived sulfonyl fluorides and their incorporation into peptide inhibitor sequences which were unavailable until this point. The resulting peptido sulfonyl fluoride inhibitors (PSFs) are designed to target proteases which

APA, Harvard, Vancouver, ISO, and other styles

16

Johnston, Brian T. "Serotonin-Expressing Cells in the Corpus of the Stomach Originate from Bone Marrow: A Master’s Thesis." eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/639.

Full text

Abstract:

Neurogenin 3 and its downstream target NeuroD are basic helix-loop-helix transcription factors which promote endocrine differentiation in the gastrointestinal tract. However, mice lacking Ngn3 still produce several hormones in the stomach. Lineage tracing mouse models demonstrated that a majority of hormone cells in the corpus region of the stomach did not express Ngn3 or NeuroD during differentiation. Serotonin and histamine cells were entirely NeuroD-independently derived, and serotonin cells were additionally entirely Ngn3-independently derived. In this study, we isolated serotonin and hist

APA, Harvard, Vancouver, ISO, and other styles

17

Merithew, Eric Lee. "Structural Basis for Rab5 Activation and Effector Specificity in Endosome Tethering: A Dissertation." eScholarship@UMMS, 2004. https://escholarship.umassmed.edu/gsbs_diss/278.

Full text

Abstract:

As critical regulators of vesicular trafficking, Rab proteins comprise the largest GTPase family, with thirty-eight functionally distinct members and another twenty isoforms in the human genome. Activated Rab GTPases interact with effector proteins involved in vesicle formation, transport, tethering, docking and fusion. The specificity of Rab interactions with effectors and regulatory factors plays a central role with respect to the fidelity of membrane trafficking. Rab recognition determinants and the mechanisms underlying interactions with structurally diverse regulatory factors and effector

APA, Harvard, Vancouver, ISO, and other styles

18

Marini, Joseph Thomas. "Development and implementation of a FT-ICR mass spectrometer for the investigation of ion conformations of peptide sequence isomers containing basic amino acid residues by gas-phase hydrogen/deuterium exchange." Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/115.

Full text

Abstract:

The gas-phase hydrogen/deuterium (H/D) exchange of protonated di- and tripeptides containing a basic amino acid residue has been studied with a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. Bimolecular reactions are monitored as a function of time providing exchange efficiencies and temporal distributions for the peptide ions. Results from these experiments indicated that position of the basic residue within the peptide (i.e. N-terminal, internal, or C-terminal) influences gas-phase H/D exchange, suggesting unique peptide ion conformations. The FT-ICR mass spectrometer

APA, Harvard, Vancouver, ISO, and other styles

19

Smith, Samantha Jane. "Amino acid neurotransmitter function in the prefrontal cortex : neurochemical basis for modulation via potential targets for antipsychotic drugs." Thesis, University of Sheffield, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.401170.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Wessling-Resnick, Marianne. "Molecular Basis of the Mechanism and Regulation of Receptor-GTP Binding Protein Interactions: A Thesis." eScholarship@UMMS, 1997. https://escholarship.umassmed.edu/gsbs_diss/100.

Full text

Abstract:

The photon receptor, rhodopsin, and the GTP-binding regulatory protein, transducin, belong to a family of G protein-coupled receptors. The activation process through which guanine nucleotide exchange of the G protein is accomplished was investigated utilizing these components of the visual transduction system. Rhodopsin, modelled as an enzyme in its interaction with substrates, transducin and guanine nucleotides, was characterized to catalyze the G protein's activation by a double-displacement mechanism. Remarkable allosteric behavior was observed in these kinetic studies. Equilibrium binding

APA, Harvard, Vancouver, ISO, and other styles

21

Zhou, Mingyan. "Structural and functional analysis of a novel organic cation/monoamine transporter PMAT in the SLC29 family /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/7979.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Chacko, Benoy M. "The Structural Basis for the Phosphorylation-Induced Activation of Smad Proteins: a Dissertation." eScholarship@UMMS, 2004. https://escholarship.umassmed.edu/gsbs_diss/161.

Full text

Abstract:

The Smad proteins transduce the signal of transforming growth factor-β (TGF-β) and related factors from the cell surface to the nucleus. Following C-terminal phosphorylation by a corresponding receptor kinase, the R-Smad proteins form heteromeric complexes with Smad4. These complexes translocate into the nucleus, bind specific transcriptional activators and DNA, ultimately modulating gene expression. Though studied through a variety of means, the stoichiometry of the R-Smad/Smad4 complex is unclear. We investigated the stoichiometry of the phosphorylation-induced R-Smad/Smad4 complex by using

APA, Harvard, Vancouver, ISO, and other styles

23

O'Rourke, Patrick. "Structural studies to inform antimicrobial drug discovery and the basis of immunity against T6 effectors." Thesis, University of Dundee, 2013. https://discovery.dundee.ac.uk/en/studentTheses/f4b1cd50-c6b3-4cbb-b313-344106bfce5c.

Full text

Abstract:

Work presented in this thesis is in two parts. Part one: The X-ray crystal structures of potential antimicrobial drug targets. The protein IspF (2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, EC: 4.6.1.12) from two pathogens (Burkholderia cenocepacia and Plasmodium falciparum) has been investigated. IspF is an enzyme of isoprenoid-precursor biosynthesis and is considered to be a potential drug target. The results of structural and fragment-screening efforts presented here inform early stage drug discovery efforts. The structure of the PabC protein (4-amino-4-deoxychorismate lyase, EC: 4

APA, Harvard, Vancouver, ISO, and other styles

24

Lekholm, Emilia. "Solute Carriers in Metabolism : Regulation of known and putative solute carriers in the central nervous system." Doctoral thesis, Uppsala universitet, Funktionell farmakologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-331328.

Full text

Abstract:

Solute carriers (SLCs) are membrane-bound transporter proteins, important for nutrient, ion, drug and metabolite transport across membranes. A quarter of the human genome codes for membrane-bound proteins, and SLCs make up the largest group of transporter proteins. Due to their ability to transport a large repertoire of substances across, not just the plasma membrane, but also the membrane of internal organelles, they hold a key position in maintaining homeostasis affecting metabolic pathways. Unfortunately, some of the more than 400 identified SLCs are still not fully characterized, even thou

APA, Harvard, Vancouver, ISO, and other styles

25

Flügel, Veronika M. Verfasser], Sabine [Akademischer Betreuer] Schneider, and Aymelt [Akademischer Betreuer] [Itzen. "Expressed Cyclopeptide Libraries as Selective Inhibitors for RNA-Protein Interactions. Structural Basis for the Site-Specific Incorporation of Non-Natural Amino Acids into Peptides and Proteins / Veronika M. Flügel. Gutachter: Aymelt Itzen ; Sabine Schneider. Betreuer: Sabine Schneider." München : Universitätsbibliothek der TU München, 2014. http://d-nb.info/1064075541/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Gholami, Sara [Verfasser]. "Association of neighboring β-Strands to form the β-barrel structure of the voltage-dependent anion channel, human isoform 1 (hVDAC1) precedes membrane insertion and is largely driven by polar interactions between basic and acidic amino acid side-chains / Sara Gholami". Kassel : Universitätsbibliothek Kassel, 2020. http://d-nb.info/1232431893/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Yeh, Hsin-Yi, and 葉欣怡. "The Importance of the Three Basic Amino Acids in Subregion 1.2 to the Structural and Functional Properties of B. subtilis sigA Factor." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/65348739988578678738.

Full text

Abstract:

碩士<br>國立中興大學<br>生物化學研究所<br>93<br> factors in the 70 family can be classified into the primary and alternative  factors according to their physiological functions and amino acid sequence similarity. The primary  factors are composed of four conserved regions, with the conserved region 1 being divided into two subregions. Region 1.1 is poorly conserved; however, region 1.2 is well conserved. We found previously that deletion of 103 amino acid residues from the N terminus of Bacillus subtilis A affects the efficiency of promoter DNA binding of the truncated A-RNA polymerase and/or the stab

APA, Harvard, Vancouver, ISO, and other styles

28

Chun-Hsiung, Chen, and 陳俊雄. "Discussion of Renal uptake of 111In-DOTATOC by Basic Amino Acid." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/05360060405493558854.

Full text

Abstract:

碩士<br>國立中興大學<br>獸醫學系<br>92<br>Somatostatin receptors have been identified in different kinds of tumors such as neuroendocrine tumors and tumors of the central nervous system, breast, lung and lymphatic tissue. These observations have served as the biomolecular basis for the clinical use of radiolabelled somatostatin analogues for diagnostic and radionuclide therapy applications. DOTATOC, a somatostatin analogue, has been found to be easily and stably labelled with 111In for purposes. Because of 111In -DOTATOC has kidney toxicity, this research uses positive charge amino acid to compare the

APA, Harvard, Vancouver, ISO, and other styles

29

Han, Hyo-Young. "Cloning of the pmb gene encoding a basic amino acid transport protein in Neurospora crassa." Thesis, 1993. http://hdl.handle.net/10125/9359.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Moodley, Arshnee. "The molecular basis of glycopeptide Resistence in two Clinical Isolates: Bacillus Lentus RSA1208 and Paenibacillus Thiaminolyticus RSA 1221." Thesis, 2006. http://hdl.handle.net/10539/1437.

Full text

Abstract:

9902930F Masters Disssertation Faculty of Health Sciences<br>The molecular mechanisms of glycopeptide resistance in two Gram-positive clinical isolates, Bacillus lentus RSA1208 and Paenibacillus thiaminolyticus RSA1221 were investigated. The glycopeptide resistance genotypes were determined by PCR. If van genes were detected, recombinant DNA techniques and sequencing were used to determine the gene sequence. The location of the resistance determinant was investigated using Southern hybridization techniques. To determine the 5’ and 3’ ends flanking the resistance operon, sub-genomic libraries

APA, Harvard, Vancouver, ISO, and other styles

31

Lin, Chang-Ching, та 林昌慶. "Aldol reaction Studies of β-amino α,β-unsaturated γ-thiolactone under Basic and Lewis acid conditions". Thesis, 2000. http://ndltd.ncl.edu.tw/handle/84056287302188170852.

Full text

Abstract:

碩士<br>朝陽大學<br>應用化學系碩士班<br>88<br>A novel procedure for the synthesis of achiral thiopenone from Methyl 3-pyrrolidino(E)-2-butenoate and it’s application on the studies of Aldol reactions under basic(including the temperature,counter ion , base reagent effect) and Lewis acid conditions (Lewis such as BF3.Et2 , SnCl4 , TiCl4) to generate syn - product or anti-product will be discussed.

APA, Harvard, Vancouver, ISO, and other styles

32

Souffrant, Michael. "Establishing the Relationship Between Function and Dynamics Within the Gated Mechanism of D-arginine Dehydrogenase." 2016. http://scholarworks.gsu.edu/chemistry_theses/92.

Full text

Abstract:

Enzymes are ubiquitous in biological systems. They catalyze chemical reactions and are involved in many biochemical processes. The enzyme of interest is Pseudomonas aeruginosa D-arginine dehydrogenase (PaDADH). This flavin-dependent enzyme is composed of approximately 375 amino acid residues and has a broad substrate specificity with D-amino acids. A water recognition motif, observed in roughly 1200 non-redundant protein data bank (PDB) structures, was revealed to be embedded near the active site of PaDADH. This motif coincides with the conformational changes of the enzyme’s gated mechanism. M

APA, Harvard, Vancouver, ISO, and other styles

33

Pena, Maria João Rodrigues Carvalho. "Acute effect of a phenylalanine-free amino acid mixture on metebolic parameters from basic science to clinical phenylketonuria." Dissertação, 2014. https://repositorio-aberto.up.pt/handle/10216/88056.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Pena, Maria João Rodrigues Carvalho. "Acute effect of a phenylalanine-free amino acid mixture on metebolic parameters from basic science to clinical phenylketonuria." Master's thesis, 2014. https://repositorio-aberto.up.pt/handle/10216/88056.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Lee, I.-fang, and 李逸芳. "Nuclear Trafficking Directed by Basic Amino Acid Clusters: role of the NH2-terminal region of human ribosomal protein L7." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/67515717779177658152.

Full text

Abstract:

碩士<br>國立陽明大學<br>遺傳學研究所<br>93<br>To understand the effect of the nuclear localization signal (NLS) and the nucleolar localization signal (NoLS) within protein structure to the nuclear trafficking, the NH2-terminal region of human ribosomal protein L7 was chosen as the study model, because the NH2 terminus of L7 is capable of entering the nucleus and the nucleolus. The NH2 terminus can be divided into four motifs, N1, N2, N3 and N4, according to the knowledge of the SV 40 T antigen NLS. Each motif was separately fused to the NH2 terminus of 3 copies of enhanced green fluorescence protein ((EGFP)

APA, Harvard, Vancouver, ISO, and other styles

36

Puri, Kamal Deep. "Structure-Function Relationship Of Winged Bean (Psophocarpus Tetragonolobus) Basic Agglutinin (WBA I ) : Carbohydrate Binding, Domain Structure And Amino Acid Sequence Analysis." Thesis, 1993. http://etd.iisc.ernet.in/handle/2005/2440.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Cheng, Li-Chi, та 鄭笠綺. "Study of the reason responsible for the early cell lysis caused by substitutions for the three basic amino acid residues in subregion 1.2 of Bacillus subtilis σA factor". Thesis, 2015. http://ndltd.ncl.edu.tw/handle/v58835.

Full text

Abstract:

碩士<br>國立中興大學<br>生物化學研究所<br>103<br>The primary σ factor of Bacillus subtilis, σA, comprises four conserved regions, each containing two to four subregions. It was found that deletion of 103 amino acid residues from the N terminus of the σA would affect the efficiency of promoter DNA binding of the truncated σA-RNA polymerase, the stability of the closed binary complex and the efficiency of open complex formation. Sequence alignment of σ factor has revealed three conserved basic amino acid residues, R103, K107, and R111, in the N-terminus of subregion 1.2 of Bacillus subtilis σA factor. On the b

APA, Harvard, Vancouver, ISO, and other styles

38

Li, Chang-Chin, and 李長錦. "Study on complex structure between human basic fibroblast growth factor (hFGF-2) and anti-angiogenic drug SSR 〔2-amino-5-(1-(methoxy-2-methylindolizin-3-yl)methanone) benzoic acid〕by NMR." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/18216581317953400170.

Full text

Abstract:

碩士<br>國立清華大學<br>化學系<br>96<br>The fibroblast growth factors (FGFs) are members of a large family of signaling molecules with many diverse biological activities that include cellular growth, proliferation and tumor growth. FGF-2 is a single-chain heparin-binding polypeptide and has been detected in normal and malignant cells and shown for its mitogenic and angiogenic activity with a consequent crucial role in cell differentiation and development. In particular, FGF-2 can be secreted to the extracellular medium where it switches on signal transduction pathways by binding to and activation of cell

APA, Harvard, Vancouver, ISO, and other styles

39

Ward, Matthew Norman. "The molecular basis of colour vision in colourful fish : four long wave-sensitive (LWS) opsins in guppies (Poecilia reticulata) are defined by amino acid substitutions at key functional sites." Thesis, 2008. http://hdl.handle.net/1828/2490.

Full text

Abstract:

Comparisons of functionally important changes at the molecular level in model systems have identified key adaptations driving isolation and speciation. For example, recent studies suggest mutations in opsins, the genes that encode retinal photoreceptors, influence colour-based female mate choice and have, thereby, contributed to the radiation of African cichlids. To test the hypothesis that the evolution of elaborate colouration in guppies (Poecilia reticulata) is also associated with opsin gene diversity, long wavelength-sensitive (LWS) opsin genes were sequenced in six species of the family

APA, Harvard, Vancouver, ISO, and other styles

40

Ehlert, Andrea. "The Arabidopsis C/S1 bacic leucine Zipper transcription factor network:Impact of heterodimer formation on target gene transcription." Doctoral thesis, 2010. http://hdl.handle.net/11858/00-1735-0000-0006-ADE1-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!