Relevant bibliographies by topics / Batch Manufacturing process

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Batch Manufacturing process'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Batch Manufacturing process"

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Burcham, Christopher L., Alastair J. Florence, and Martin D. Johnson. "Continuous Manufacturing in Pharmaceutical Process Development and Manufacturing." Annual Review of Chemical and Biomolecular Engineering 9, no. 1 (2018): 253–81. http://dx.doi.org/10.1146/annurev-chembioeng-060817-084355.

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The pharmaceutical industry has found new applications for the use of continuous processing for the manufacture of new therapies currently in development. The transformation has been encouraged by regulatory bodies as well as driven by cost reduction, decreased development cycles, access to new chemistries not practical in batch, improved safety, flexible manufacturing platforms, and improved product quality assurance. The transformation from batch to continuous manufacturing processing is the focus of this review. The review is limited to small, chemically synthesized organic molecules and en
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Xie, Xiangzhong, and René Schenkendorf. "Robust Process Design in Pharmaceutical Manufacturing under Batch-to-Batch Variation." Processes 7, no. 8 (2019): 509. http://dx.doi.org/10.3390/pr7080509.

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Model-based concepts have been proven to be beneficial in pharmaceutical manufacturing, thus contributing to low costs and high quality standards. However, model parameters are derived from imperfect, noisy measurement data, which result in uncertain parameter estimates and sub-optimal process design concepts. In the last two decades, various methods have been proposed for dealing with parameter uncertainties in model-based process design. Most concepts for robustification, however, ignore the batch-to-batch variations that are common in pharmaceutical manufacturing processes. In this work, a
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Gao, Ruiyan. "The transition from batch to continuous manufacturing for tablet manufacturing performance comparison and control system review." Applied and Computational Engineering 7, no. 1 (2023): 685–91. http://dx.doi.org/10.54254/2755-2721/7/20230314.

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The pharmaceutical industry is motivated to improve tablet productivity in order to adapt to the expanding drug market. One innovative way is the transition of the traditional batch tablet manufacturing process to a continuous process. This paper aims to review the performance of continuous tablet manufacturing processes. From the comparison of continuous to traditional batch processes, the continuous tablet manufacturing process demonstrates improvements in production flexibility, robustness, and ultimately process profitability. The continuous process is proven to mix drug particles with mor
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Stephanopoulos, George, Shahin Ali, Andreas Linninger, and Enrique Salomone. "Batch process development: From reactions to manufacturing systems." Computers & Chemical Engineering 23 (June 1999): S975—S984. http://dx.doi.org/10.1016/s0098-1354(99)80232-4.

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Yue, Ming Yue, and Yi Dan Zhou. "Progress of Theoretical Research-Oriented Multi-Species Small Batch Machining Process." Applied Mechanics and Materials 364 (August 2013): 470–73. http://dx.doi.org/10.4028/www.scientific.net/amm.364.470.

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With the rapid development of machinery manufacturing industry, multi variety and small batch production has gradually become one of the main means of manufacturing enterprises. On the basis of describing the characteristics and meaning of multi variety and small batch production, this article summarizes its domestic and international situation of machinery process theory, optimization and evaluation methods, presents several methods of mathematical description and model for multi variety and small batch production and finally summarize the trends of matching problem between the processing tec
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James, D. "Batch process automation." Manufacturing Engineer 85, no. 6 (2006): 36–41. http://dx.doi.org/10.1049/me:20060604.

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Yu, Zhonghua. "ALGORITHM OF QUALITY CONTROL IN SMALL BATCH MANUFACTURING PROCESS." Chinese Journal of Mechanical Engineering 37, no. 08 (2001): 60. http://dx.doi.org/10.3901/jme.2001.08.060.

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Braglia, Marcello, Roberto Gabbrielli, and Francesco Zammori. "Consignment stock theory with a fixed batch manufacturing process." International Journal of Production Research 51, no. 8 (2013): 2377–98. http://dx.doi.org/10.1080/00207543.2012.740577.

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Kim, Yong-Jae, and Byung-Soo Kim. "Population-Based Meta-Heuristic Algorithms for Integrated Batch Manufacturing and Delivery Scheduling Problem." Mathematics 10, no. 21 (2022): 4127. http://dx.doi.org/10.3390/math10214127.

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This paper addresses an integrated scheduling problem of batch manufacturing and delivery processes with a single batch machine and direct-shipping trucks. In the manufacturing process, some jobs in the same family are simultaneously processed as a production batch in a single machine. The batch production time depends only on the family type assigned to the production batch and it is dynamically adjusted by batch deterioration and rate-modifying activities. Each job after the batch manufacturing is reassigned to delivery batches. In the delivery process, each delivery batch is directly shippe
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Taga (Sapunaru), Olga Valerica, Claudia Irina Koncsag, Cosmin Jinescu, and Alina Monica Mares. "Simulation and Optimization of Isopropyl Lactate Manufacturing Process." Revista de Chimie 70, no. 9 (2019): 3335–37. http://dx.doi.org/10.37358/rc.19.9.7544.

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The new chemical processes are investigated in laboratory, usually in batch, with pure reactants, and specific laboratory methods applied for the purification of the products. Scaling-up processes means passing from batch to continuous process, using feed with impurificators, industrial equipment for separation and recirculation or purge for an economic operation with special care for safety and environment. This is why, following a study in laboratory for isopropyl lactate obtaining by transesterification in reactive distillation system, a flowsheet of the industrial process was proposed in t
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Dissertations / Theses on the topic "Batch Manufacturing process"

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Mock, Theresa Lai-Hing. "Reducing process variability in chemical batch manufacturing." Thesis, Massachusetts Institute of Technology, 1992. http://hdl.handle.net/1721.1/12841.

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Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1992 and Thesis (M.S.)--Sloan School of Management, 1992.<br>Includes bibliographical references (p. 145-148).<br>by Theresa Lai-Hing Mock.<br>M.S.
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Salleh, Yusof Md. "Total control of batch process plant." Thesis, University of Sussex, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334204.

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Liu, Zhen Hai. "An advanced process manufacturing system : design and application to a food processing pilot plant." Thesis, Imperial College London, 1995. http://hdl.handle.net/10044/1/8694.

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Macmillan, Stanley. "Constraints management in a continuous-batch process." Diss., Pretoria : [s.n.], 2004. http://upetd.up.ac.za/thesis/available/etd-08082004-070610.

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Yang, Jian. "An asynchronous decision process (ADP) approach for integrated planning in batch-sized manufacturing industry." Thesis, Lancaster University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337468.

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Mazariegos, Carlos. "Batch sizing strategy & production load leveling in a multi-step chemical manufacturing process." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/34842.

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Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management; and, (S.M.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering; in conjunction with the Leaders for Manufacturing Program at MIT, 2005.<br>Includes bibliographical references (p. 111).<br>In the last couple of years Eastman Kodak Company went through major changes in its strategic direction. The same disruptive technologies that they helped develop for digital imaging have shaped a new industry, and the market requirements and preferences for photography have changed dramatically. Some of the
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Carter, Lionel. "The development of a quality assurance methodology for small batch manufacture in an advanced manufacturing environment." Thesis, Brunel University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318423.

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Thiruppalli, Shridharan. "Incremental generation of alternative process plans for integrated manufacturing." Ohio University / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1175008853.

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Walker, Helen R. "The design and development of a computer aided process planning decision support system within the small batch, discrete parts manufacturing environment." Thesis, Brunel University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277627.

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Facco, Pierantonio. "DEVELOPMENT OF MULTIVARIATE STATISTICAL TECHNIQUES FOR QUALITY MONITORING IN THE BATCH MANUFACTURING OF HIGH VALUE ADDED PRODUCTS." Doctoral thesis, Università degli studi di Padova, 2009. http://hdl.handle.net/11577/3426077.

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Although batch processes are “simple” in terms of equipment and operation design, it is often difficult to ensure consistently high product quality. The aim of this PhD project is the development of multivariate statistical methodologies for the realtime monitoring of quality in batch processes for the production of high value added products. Two classes of products are considered: those whose quality is determined by chemical/physical characteristics, and those where surface properties define quality. In particular, the challenges related to the instantaneous estimation of the product quality
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Books on the topic "Batch Manufacturing process"

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Monahan, George E. Product-process relations in batch manufacturing. College of Commerce and Business Administration, University of Illinois at Urbana-Champaign, 1989.

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Walker, Helen R. The design and development of a computer aided process planning decision support system within the small batch, discrete parts manufacturing environment. Brunel University, 1990.

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Monahan, George E. Product-process relations in bath manufacturing. College of Commerce and Business Administration, University of Illinois at Urbana-Champaign, 1990.

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Trietsch, Dan. Optimal transfer lots for batch manufacturing: A basic case and extensions. Naval Postgraduate School, 1987.

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National Conference on Manufacturing Research (15th 1999 University of Bath). Advances in manufacturing technology XIII: Proceedings of the fifteenth National Conference on Manufacturing Research, University of Bath, UK, 6-8 September 1999. Professional Engineering Pub., 1999.

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Diwekar, Urmila. Batch Processing: Modeling and Design. Taylor & Francis Group, 2014.

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Diwekar, Urmila. Batch Processing: Modeling and Design. Taylor & Francis Group, 2014.

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Diwekar, Urmila. Batch Processing: Modeling and Design. Taylor & Francis Group, 2010.

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Diwekar, Urmila. Batch Processing: Modeling and Design. Taylor & Francis Group, 2014.

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Diwekar, Urmila. Batch Processing: Modeling and Design. Taylor & Francis Group, 2014.

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Book chapters on the topic "Batch Manufacturing process"

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Peng, Limei, Pengbo Ji, Yueqing Qian, Yong Yang, Hongyu Tian, and Junling Han. "Quality Control of Small Batch product in Manufacturing Process." In Proceedings of the 23rd Pacific Basin Nuclear Conference, Volume 2. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-8780-9_92.

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Rewers, Paulina, Marta Czaja, Kamila Janczura, and Jacek Diakun. "Determination of the Production Frequency and Batch Size for the Manufacturing Process." In Lecture Notes in Mechanical Engineering. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-68014-5_8.

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Huse, Timo, and Laura Rehberg. "The Potential of High Speed Sintering for Small Series in the Automotive Industry." In Advances in Automotive Production Technology – Towards Software-Defined Manufacturing and Resilient Supply Chains. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-27933-1_29.

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AbstractIndividualization in the high-performance segment within the automotive industry is becoming increasingly important. Especially when small volumes are required, conventional manufacturing processes often no longer prove profitable. The use of additive processes in general and high-speed sintering (HSS) in particular offer the freedom to produce complex organic shapes in a cost-effective and resource-saving manner from batch size one onwards. The HSS process is a powder bed-based additive manufacturing process in which thermoplastics are sintered at a constant layer time using an infrar
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Bay, Christian, Niko Nagengast, Hans-Werner Schmidt, Frank Döpper, and Christian Neuber. "Environmental Assessment of Recycled Petroleum and Bio Based Additively Manufactured Parts via LCA." In Lecture Notes in Mechanical Engineering. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-28839-5_75.

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AbstractAdditive Manufacturing (AM) as much as sustainability aspects gained increasing attention in the last couple of years. The vision of resource-efficient manufacturing at batch size one is often claimed as an outstanding property of AM. Fused Filament Fabrication, as one of the most used AM technologies, satisfies this statement only in a restricted sense, through simple handling for non-experts and low-cost materials and machines. Next to performance-driven and process-influencing attributes, the question of a general ecological improvement through thermo-mechanical recycling rises. The
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Böß, Volker, Berend Denkena, Sven Friebe, and Markus Hein. "Simulation-Based Process Design of Recontouring Technologies." In Regeneration of Complex Capital Goods. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-51395-4_13.

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AbstractEngine manufacturers generate about 50% of their total turnover with maintenance. Damaged parts can either be replaced by spare parts or can be regenerated by e.g. local welding processes. One major step of the manufacturing part of the process chain for regeneration after the material deposition is the removal of excess weld material by cutting, which is called recontouring. Recontouring is often the last process step, which defines the final surface integrity and thus the performance of the repaired parts. Thereby, each component has a batch size of one by reason of individuality. In
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Lanz, Minna, Jyrki Latokartano, and Roel Pieters. "Digital Innovation Hubs for Enhancing the Technology Transfer and Digital Transformation of the European Manufacturing Industry." In IFIP Advances in Information and Communication Technology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-72632-4_15.

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AbstractThe European manufacturers are dealing with shorter product life-cycles and smaller batch sizes. Especially, the high-value products tend to be fully personalised, which makes the automatisation of the production difficult. However, the trend is that the production needs to be predictable and fully traceable to the process and even to the tool level. This adds pressure to have better data collection methods and also to increase of automation in different levels of production. The emergence of new technologies in the field of robotics allows the utilisation of automation in flexible man
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McMahon, Chris. "Innovative Manufacturing Research Centre, University of Bath." In Design process improvement. Springer London, 2005. http://dx.doi.org/10.1007/978-1-84628-061-0_21.

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Wetzig, Tony, Matthias Schwarz, Leandro Schöttler, Patrick Gehre, and Christos G. Aneziris. "Functionalized Feeders, Hollowware, Spider Bricks and Starter Casting Tubes for Increasing the Purity in Steel Casting Processes." In Multifunctional Ceramic Filter Systems for Metal Melt Filtration. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-40930-1_32.

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AbstractAlthough continuous casting became the state of the art for the casting of ordinary steel grades, ingot casting by bottom teeming still has relevance in the steelmaking industry, especially for the manufacturing of specialty and alloy steels. As for every casting process, the ever-increasing quality requirements by customers lead to increased demand for new technologies to increase the purity of the cast steel melt regarding its inclusion content. Due to the special design of the bottom-teeming ingot casting facility and the discontinuous operation as batch process, the application of
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Lauer, Sascha, Sebastian Rieck, Martin-Christoph Wanner, and Wilko Flügge. "Partial Automated Multi-Pass-Welding for Thick Sheet Metal Connections." In Annals of Scientific Society for Assembly, Handling and Industrial Robotics 2021. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-74032-0_33.

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AbstractThe production of tubular-node-connections, which are required for the construction of offshore wind energy plants or converter platforms, is subject to high manufacturing standards. The welding process is currently carried out manually and requires a great deal of experience on the part of the welder. In this process, one or more branch member pipes are welded to a base pipe, which vary in their diameters and alignment to each other. This results in a small batch size for which no standard automation solution can be considered. The approach of a pre-defined offline path-planning is no
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Biltgen, Jacques, Sascha Lauer, Martin-Christoph Wanner, and Wilko Flügge. "Digital Geometry Recording for Automation of the One-Off Production of Pipes." In Annals of Scientific Society for Assembly, Handling and Industrial Robotics 2022. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-10071-0_22.

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AbstractThe manual production in pipeline construction is often related to the fact that either the capacities for automation are lacking or the production is too individual for a simple automation solution. However, automated production would increase productivity and quality, especially in metal processing. The challenge in the manufacturing process of fitting tubes is the batch sizes of one. Nevertheless, a non-time-consuming programming solution must be found to integrate a robot-based solution economically into the production chain. Offline path planning based on CAD models would be a sui
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Conference papers on the topic "Batch Manufacturing process"

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Rhim, Jungsoo, and Zoltan Nagy. "Technoeconomic and Sustainability Analysis of Batch and Continuous Crystallization for Pharmaceutical Manufacturing." In Foundations of Computer-Aided Process Design. PSE Press, 2024. http://dx.doi.org/10.69997/sct.107722.

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Continuous manufacturing in pharmaceutical industries has shown great promise to achieve process intensification. To better understand and justify such changes to the current status quo, a technoeconomic analysis of a continuous production must be conducted to serve as a predictive decision-making tool for manufacturers. This paper uses PharmaPy, a custom-made Python-based library developed for pharmaceutical flowsheet analysis, to simulate an annual production cycle for a given active pharmaceutical ingredient (API) of varying production volumes for a batch crystallization system and a contin
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Hung, Hong Yee, and Zhao Jinsong. "Enhancing Batch Chemical Manufacturing via Development of Deep Learning based Predictive Monitoring with Transfer Learning." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.188760.

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Batch chemical processes face significant challenges due to frequent operational shifts and varying conditions, requiring models to be retrained for each new scenario. This high retraining demand limits the scalability of traditional process monitoring systems, making them unsuitable for dynamic batch operations. To address this, we propose a transfer learning-based framework that enhances adaptability by reusing learned features across different batch conditions, reducing the need for extensive retraining. Proposed method integrates Temporal Convolutional Networks (TCNs) for capturing tempora
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Barhate, Yash, Daniel Casas-Orozco, Daniel J. Laky, Gintaras V. Reklaitis, and Zoltan K. Nagy. "Hybrid Rule-based and Optimization-driven Decision Framework for the Rapid Synthesis of End-to-End Optimal (E2EO) and Sustainable Pharmaceutical Manufacturing Flowsheets." In Foundations of Computer-Aided Process Design. PSE Press, 2024. http://dx.doi.org/10.69997/sct.115998.

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In this paper, a hybrid heuristic rule-based and deterministic optimization-driven process decision framework is presented for the analysis and optimization of process flowsheets for end-to-end optimal (E2E0) pharmaceutical manufacturing. The framework accommodates various operating modes, such as batch, semi-batch and continuous, for the different unit operations that implement each manufacturing step. To address the challenges associated with solving process synthesis problems using a simulation-optimization approach, heuristic-based process synthesis rules are employed to facilitate the red
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Shahab, Mohammad, Kensaku Matsunami, Zoltan Nagy, and Gintaras Reklaitis. "Process analysis of end-to-end continuous pharmaceutical manufacturing using PharmaPy." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.154363.

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As pharmaceutical manufacturing is transitioning from traditional batch to continuous manufacturing (CM), there is a lack of tools for CM design and development, which can integrate drug substance and drug product unit operations for overall evaluation. Recently, a Python-based PharmaPy framework was proposed to advance the design, simulation, and analysis of continuous pharmaceutical processes. However, the initial library of models only addressed upstream drug substance processing. In this work, new capabilities, including drug product unit operations such as feeder, blender, and tablet pres
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Pasieka, Engelbert, and Sebastian Engell. "Evolutionary Algorithm Based Real-time Scheduling via Simulation-Optimization for Multiproduct Batch Plants." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.183349.

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Production scheduling in the process industry is an area of significant activity in research and of great practical importance for the performance of industrial companies. In the vast majority of research papers, the scheduling problem is formulated as an off-line problem where a number of jobs is scheduled on a number of resources and the efficiency of the formulation and the solution algorithms is discussed. In reality, however, scheduling is a continuous activity that has to react to the arrival of new orders, to variations in processing times, breakdowns, lack of resources etc. This is ter
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Kay, Sam, Mengjia Zhu, Amanda Lane, Jane Shaw, Philip Martin, and Dongda Zhang. "Machine Learning-Aided Robust Optimisation for Identifying Optimal Operational Spaces under Uncertainty." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.188062.

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Process optimisation and quality control are crucial in process industries for minimising product waste and improving plant economics. Identifying robust operational regions that ensure both product quality and performance is particularly valued in industries. However, this task is complicated by operational uncertainties, which can lead to violations of product quality constraints and significant batch discards. We propose a novel robust optimisation strategy that integrates advanced machine learning and process systems engineering to systematically identify optimal operational regions under
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Berthier, Louis, Ahmed Shokry, Eric Moulines, Guillaume Ramelet, and Sylvain Desroziers. "Knowledge Discovery in Large-Scale Batch Processes through Explainable Boosted Models and Uncertainty Quantification: Application to Rubber Mixing." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.183525.

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Rubber mixing (RM) is a vital batch process producing high-quality composites, which serve as input material for manufacturing different types of final products, such as tires. Due to its complexity, this process faces two main challenges regarding the final quality: i) lack of online measurement and ii) limited comprehension of the influence of the different factors involved in the process. While data-driven and machine learning (ML) based soft-sensing methods have been widely applied to address the first challenge, the second challenge, to the best of the author's knowledge, has not yet been
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Sorensen, Eva, Dian Ning Chia, and Fanyi Duanmu. "A Superstructure Approach for Optimization of Simulated Moving Bed (SMB) Chromatography." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.130271.

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One of the most successful continuous high-performance liquid chromatography (HPLC) processes for drug manufacturing is the Simulated Moving Bed (SMB). SMB is a multi-column, continuous, chromatographic process that can handle much higher throughputs than regular batch chromatographic processes. The process is initially transient, but eventually arrives at a cyclic steady state, which makes optimization very challenging, even more so when superstructure optimization is involved. To simplify the optimization problem, many researchers fixed the SMB structure, optimizing only the continuous varia
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Hart, Tom. "Advancements in Steel Hardening Distortion Control Using a 4-Dimension High-Pressure Gas Quenching (4DQ) System." In IFHTSE 2024. ASM International, 2024. http://dx.doi.org/10.31399/asm.cp.ifhtse2024p0160.

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Abstract It is well known that distortion has and continues to present a challenge to the heat treater when hardening steel. However, recent advances in quenching technology are improving the opportunity for improved distortion control. 4 Dimension High-Pressure Gas Quenching (4DQ) is a unique gas quenching process that uses both quenching chamber design and part motion to minimize distortion during the quenching process. To understand 4DQ’s potential, the challenges of traditional batch quenching and press quenching techniques will be explored, emphasizing issues such as geometric distortion,
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Li, Ganping, Jun Zhao, and Lihui Wu. "Constrained Batch-to-Batch Optimal Control for Batch Process Based on Support Vector Regression Model with Batchwise Error Feedback." In 2011 Second International Conference on Digital Manufacturing and Automation (ICDMA). IEEE, 2011. http://dx.doi.org/10.1109/icdma.2011.86.

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