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Relevant bibliographies by topics / BC1

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Dissertations / Theses

Academic literature on the topic 'BC1'

Author: Grafiati

Published: 14 March 2023

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Dissertations / Theses on the topic "BC1"

1

Ritter, Michaela. "Cytochrom bc1 eine Studie zum Elektronentransfer der bc1-Komplexe des Bakteriums Paracoccus denitrificans und der Hefe Saccharomyces cerevisiae mittels elektrochemisch induzierter Differenzspektroskopie /." [S.l. : s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971616574.

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Baer, Kimberly Kay. "Protein Coevolution and Coadaptation in the Vertebrate bc1 Complex." Diss., CLICK HERE for online access, 2007. http://contentdm.lib.byu.edu/ETD/image/etd1994.pdf.

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3

Vallières, Cindy. "Agents antimicrobiens ciblant le complexe III de la chaîne respiratoire mitochondriale : caractérisation de nouveaux inhibiteurs et étude du développement des résistances." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00840029.

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Des inhibiteurs du complexe bc1 de la chaîne respiratoire mitochondriale ont été développés comme agents antimicrobiens pour lutter contre des pathogènes de l'Homme et de plantes. Ces drogues ciblent les poches catalytiques Qo et Qi formées par le cytochrome b. La comparaison de séquences de cette protéine montre que les sites Qo et Qi sont bien conservés entre les organismes mais qu'il existe toutefois des variations qui pourraient expliquer leur différence de sensibilité aux drogues. A l'aide du modèle levure S. cerevisiae, nous avons étudié les déterminants de la résistance/sensibilité natu

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4

Gordon, James Alexander. "Design and synthesis of novel cytochrome bc1 inhibitors for the treatment of toxoplasmosis." Thesis, University of Leeds, 2018. http://etheses.whiterose.ac.uk/22638/.

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Toxoplasmosis is a highly prolific and neglected disease, and current treatments fail to adequately address the challenges it presents. As such development of new more efficacious treatments, tailored to the complex nature of the infection, is required. The causative parasite Toxoplasma gondii is a resilient and resourceful organism, adept at invasion, avoidance and survival within its host. The cytochrome bc1 complex has been proven to be a validated target for the treatment of a number of apicomplexan parasitic diseases, including both malaria and toxoplasmosis. Recent work has also identifi

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5

Xue, Vincent. "Modeling and designing Bc1-2 family protein interactions using high-throughput interaction data." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/120446.

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Thesis: Ph. D., Massachusetts Institute of Technology, Computational and Systems Biology Program, 2018.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 153-164).<br>Protein-protein interactions (PPIs) play a major role in cellular function, mediating signal processing and regulating enzymatic activity. Understanding how proteins interact is essential for predicting new binding partners and engineering new functions. Mutational analysis is one way to study the determinants of protein interaction. Traditionally, the biophysical study of protein interactions

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6

Pacorel, Benedicte. "Targeting the Hemoglobin Degradation Pathway and the Cytochrome bc1 Complex of Plasmodium Falciparum Malaria." Thesis, University of Liverpool, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507704.

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7

Kehrein, Kirsten. "Organization of mitochondrial gene expression in yeast : Specific features of organellar protein synthesis." Doctoral thesis, Stockholms universitet, Institutionen för biokemi och biofysik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-107568.

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Mitochondria contain their own genetic system, encoding key subunits of the oxidative phosphorylation system. These subunits are expressed by an organelle-specific gene expression machinery. This work revealed a number of fundamental aspects of mitochondrial gene expression and provides evidence that this process is organized in a unique and organelle-specific manner which likely evolved to optimize protein synthesis and assembly in mitochondria. Most importantly, improving the experimental handling of ribosomes we could show that mitochondrial ribosomes are organized in large assemblies that

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8

Davoudi, Cedric-Farhad [Verfasser]. "Regulation and assembly of the cytochrome bc1-aa3 supercomplex in Corynebacterium glutamicum / Cedric-Farhad Davoudi." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2019. http://d-nb.info/1189416115/34.

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9

ACERO, LUIS FERNANDO JR. "T-CELL HOMEOSTASIS AND THE ROLE OF THE PRO-APOPTOTIC Bc1-2 FAMILY MEMBER Bim." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1126725924.

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10

Cowley, Robin Neil. "The synthesis and development of novel quinolone antimalarials targeting the bc1 protein complex of Plasmodium falciparum." Thesis, University of Liverpool, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569047.

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In recent years investigation of the biological mode of action of the antimalarial compound atovaquone has validated the Plasmodium falciparum bC1 protein complex as a target for the development of novel antimalarials. This project is concerned with the design, synthesis and development of quinolone based antimalarial compounds targeting the Qo site of the Plasmodium falciparum bC1 protein complex. -......, ..•. : - A small array of quinolone-based compounds, substituted at the 3 and 7 positions, has been developed utilising the Gould-Jacobs methodology. The synthesised compounds express activ

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