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1

Neri, Stefano. "Has healthcare rationalisation been rationale? Hospital beds and Covid-19 in Italy." SALUTE E SOCIETÀ, no. 2 (October 2021): 133–51. http://dx.doi.org/10.3280/ses2021-002-s1009.

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The outbreak of Covid-19 pandemic highlighted the existence of a hospital bed shortage in Italy, as a result of a longstanding trend. The article analyses this process by an international comparison with other Western European countries, highlighting the intensity of hospital bed reduction in Italy, as a fundamental component of NHS rationalisation. Although it was based on solid grounds, international data suggest that hospital bed reduction was probably excessive, depriving the NHS of organisational slack. Moreover, de-hospitalisation would have been matched with a stronger development of primary and community care. The relative shortage of these services, along with the lack of integrated networks between hospital and non-hospital care, explains many difficulties experienced by hospitals in tackling Covid patients. Beyond investments in health care, these elements call to re-think the organisation of health care provision at local level, questioning the purchaser-provider split.
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Markey, Thomas L. "Bees, Barley, Bēowulf and Beyla." Amsterdamer Beiträge zur älteren Germanistik 76, no. 3 (December 1, 2016): 323–52. http://dx.doi.org/10.1163/18756719-12340045.

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A primary aim of this study is its attempt to uncover a prehistoric layer of cereal grain (barley) mythology and ritual that may have backgrounded the Beowulf-poem. Toward this end, the poem and the mythological figures of Byggvir, Beyla, Scef ‘sheaf’ and Scyld ‘shield’ are interpreted in terms of a conceivable ritual context. Moreover, cereal deities, their ritualized veneration and the possible associations between them are referenced to the scourge of ergotism that once threatened much of Europe. The scope of Beowulf as not only an heroic epic but as also a cultural repository is thereby amplified.
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3

Yu, Ga Ram, Woo Yeong Choi, and Kyung Soo Kook. "Integrated Control Strategy of Multiple BESS for providing Primary Frequency Control." Transactions of The Korean Institute of Electrical Engineers 65, no. 7 (July 1, 2016): 1169–75. http://dx.doi.org/10.5370/kiee.2016.65.7.1169.

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4

Goulder, Raymond. "Primary Datasets for Case Studies of River-Water Quality." Bioscience Education 12, no. 1 (December 2008): 1–5. http://dx.doi.org/10.3108/beej.12.c3.

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5

Schieberle, Peter. "Primary odorants of pale lager beer." Zeitschrift f�r Lebensmittel-Untersuchung und -Forschung 193, no. 6 (December 1991): 558–65. http://dx.doi.org/10.1007/bf01190873.

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6

Stanghellini, M. S., J. T. Ambrose, and J. R. Schultheis. "Stigmatic Pollen Grain Deposition by Honey Bees and Bumble Bees after Single Bee Visits to Pistillate Watermelon Flowers." HortScience 33, no. 3 (June 1998): 484a—484. http://dx.doi.org/10.21273/hortsci.33.3.484a.

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As a means to assess pollinator efficiency, the number of pollen grains deposited by honey bees (Apis mellifera L.) and bumble bees (Bombus impatiens Cresson) after single visits to pistillate watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai] flowers was compared. Pistillate flowers were enclosed in nylon bags prior to anthesis, and were then exposed to single visits by each bee species (RCBD: 10 flowers per bee species per replicate; 4 replicates). Pollen grains were removed from stigmata immdiately after bee visitation by use of a glycerin jelly-gelatin mixture that was mounted onto microscope slides. Light microscopy was used to count the number of pollen grains per slide. Bumble bees deposited significantly more pollen grains than did honey bees (P < 0.05). After single bee visits to flowers, bumble bees deposited an average of 481 pollen grains, while honey bees deposited an average of 119 pollen grains. Although multiple bee visits are usually required to set watermelon fruit, this work demonstrates that bumble bees are more-efficient pollinators of watermelon at the single visit level than are honey bees.
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7

Raudoniūtė, Aušrinė. "EFFECTIVENESS OF INTEGRATED THEMATIC EDUCATIONAL ACTIVITY ABOUT BEES AND BEEKEEPING." Natural Science Education in a Comprehensive School (NSECS) 25, no. 1 (April 20, 2019): 70–80. http://dx.doi.org/10.48127/gu/19.25.70.

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For the last two years the author of this study was giving educations for adolescents and adults about bees and beekeeping in Lithuania. It was noticed that despite the lack of general knowledge about bees, people are keen on improving their comprehension about social insects. However, starting from general educational programs for preschools and primary schools there was barely information about social insects. That was a reason for further analysis of how effective children can learn from integrated educational activities organised at school. The object of the study was preschool and primary school students from one school in Vilnius, Lithuania. The aim of this study was to analyse the feedback and questionnaires that were filled with preschool and primary school students before and after the education. Then to measure the impact of this education on students' knowledge, skills and attitudes. This study could help teachers to find more ideas for social insects topic in primary school. Moreover, it was revealed what are the most common misconceptions about bees and beekeeping so it could be used to avoid possible mistakes in pupil learning. All in all, according to student reviews after education about bees and beekeeping, honey bees became more appreciable insect that was not before. And this is a little step for growing love for nature in the little human‘s heart. Keywords: educational activity, bees, honeybees, beekeeping, effectiveness, social insects, beekeeping and honey bees misconceptions.
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8

Stow, Adam, David Briscoe, Michael Gillings, Marita Holley, Shannon Smith, Remko Leys, Tish Silberbauer, Christine Turnbull, and Andrew Beattie. "Antimicrobial defences increase with sociality in bees." Biology Letters 3, no. 4 (May 15, 2007): 422–24. http://dx.doi.org/10.1098/rsbl.2007.0178.

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Evidence for the antiquity and importance of microbial pathogens as selective agents is found in the proliferation of antimicrobial defences throughout the animal kingdom. Social insects, typified by crowding and often by low genetic variation, have high probabilities of disease transmission and eusocial Hymenoptera may be particularly vulnerable because of haplodiploidy. Mechanisms they employ to reduce the risk of disease include antimicrobial secretions which are particularly important primary barriers to infection. However, until now, whether or not there is selection for stronger antimicrobial secretions when the risk of disease increases because of sociality has not been tested. Here, we present evidence that the production of progressively stronger antimicrobial compounds was critical to the evolution of sociality in bees. We found that increases in group size and genetic relatedness were strongly correlated with increasing antimicrobial strength. The antimicrobials of even the most primitive semi-social species were an order of magnitude stronger that those of solitary species, suggesting a point of no return, beyond which disease control was essential. Our results suggest that selection by microbial pathogens was critical to the evolution of sociality and required the production of strong, front-line antimicrobial defences.
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9

Gäde, Gerd, and Lutz Auerswald. "Flight metabolism in carpenter bees and primary structure of their hypertrehalosaemic peptide." Experimental Biology Online 3, no. 6 (November 1998): 1–11. http://dx.doi.org/10.1007/s00898-998-0006-2.

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10

Tao, P., and S. Y. Wang. "Letter: the effects of colectomy prior to the diagnosis of primary sclerosing cholangitis on prognosis may have been overestimated." Alimentary Pharmacology & Therapeutics 47, no. 3 (January 8, 2018): 443. http://dx.doi.org/10.1111/apt.14439.

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11

Giusti, Elena. "VIRGIL'S CARTHAGINIANS ATAEN. 1.430–6: CYCLOPES IN BEES’ CLOTHING." Cambridge Classical Journal 60 (April 30, 2014): 37–58. http://dx.doi.org/10.1017/s1750270514000013.

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Virgil's poetry has long been recognised as delving into a poetics of comparison which employs sudden shifts from the miniature to the gigantic. So too have Virgilian similes long been singled out as a privileged locus where complex inter- and intra-textual allusions serve to highlight the primary role that these similes play in the narrative and poetic context of Virgil's work. Along these lines, this paper addresses one such simile atAene.d1.430–6, where the Tyrians building Carthage are compared to busy bees working at their hive. The paper explores the impact that the recognition of the simile's inter- and intra-textual connections may have on the interpretation of the scene of Aeneas’ arrival at Carthage, and on certain long-debated aspects of the poem as a whole.
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12

YACOOB, MAY, WILLIAM BRIEGER, and SUSAN WATTS. "Primary health care: why has water been neglected?" Health Policy and Planning 4, no. 4 (1989): 328–33. http://dx.doi.org/10.1093/heapol/4.4.328.

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13

Jones, Rod. "Demand for hospital beds in primary care organisations." British Journal of Healthcare Management 17, no. 8 (August 2011): 360–67. http://dx.doi.org/10.12968/bjhc.2011.17.8.360.

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14

Pires, Eduardo J., José A. Teixeira, Tomás Brányik, Manuela Côrte-Real, and António A. Vicente. "Maintaining yeast viability in continuous primary beer fermentation." Journal of the Institute of Brewing 120, no. 1 (January 2014): 52–59. http://dx.doi.org/10.1002/jib.111.

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15

Patel, Nash, and Simon J. M. Welham. "Peptic digestion of beef myofibrils is modified by prior marination." Food & Nutrition Research 57, no. 1 (January 2013): 20294. http://dx.doi.org/10.3402/fnr.v57i0.20294.

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16

Motta, Erick V. S., Kasie Raymann, and Nancy A. Moran. "Glyphosate perturbs the gut microbiota of honey bees." Proceedings of the National Academy of Sciences 115, no. 41 (September 24, 2018): 10305–10. http://dx.doi.org/10.1073/pnas.1803880115.

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Glyphosate, the primary herbicide used globally for weed control, targets the 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) enzyme in the shikimate pathway found in plants and some microorganisms. Thus, glyphosate may affect bacterial symbionts of animals living near agricultural sites, including pollinators such as bees. The honey bee gut microbiota is dominated by eight bacterial species that promote weight gain and reduce pathogen susceptibility. The gene encoding EPSPS is present in almost all sequenced genomes of bee gut bacteria, indicating that they are potentially susceptible to glyphosate. We demonstrated that the relative and absolute abundances of dominant gut microbiota species are decreased in bees exposed to glyphosate at concentrations documented in the environment. Glyphosate exposure of young workers increased mortality of bees subsequently exposed to the opportunistic pathogen Serratia marcescens. Members of the bee gut microbiota varied in susceptibility to glyphosate, largely corresponding to whether they possessed an EPSPS of class I (sensitive to glyphosate) or class II (insensitive to glyphosate). This basis for differences in sensitivity was confirmed using in vitro experiments in which the EPSPS gene from bee gut bacteria was cloned into Escherichia coli. All strains of the core bee gut species, Snodgrassella alvi, encode a sensitive class I EPSPS, and reduction in S. alvi levels was a consistent experimental result. However, some S. alvi strains appear to possess an alternative mechanism of glyphosate resistance. Thus, exposure of bees to glyphosate can perturb their beneficial gut microbiota, potentially affecting bee health and their effectiveness as pollinators.
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17

Dillon, Michael E., and Robert Dudley. "Surpassing Mt. Everest: extreme flight performance of alpine bumble-bees." Biology Letters 10, no. 2 (February 2014): 20130922. http://dx.doi.org/10.1098/rsbl.2013.0922.

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Animal flight at altitude involves substantial aerodynamic and physiological challenges. Hovering at high elevations is particularly demanding from the dual perspectives of lift and power output; nevertheless, some volant insects reside and fly at elevations in excess of 4000 m. Here, we demonstrate that alpine bumble-bees possess substantial aerodynamic reserves, and can sustain hovering flight under hypobaria at effective elevations in excess of 9000 m, i.e. higher than Mt. Everest. Modulation of stroke amplitude and not wingbeat frequency is the primary means of compensation for overcoming the aerodynamic challenge. The presence of such excess capacity in a high-altitude bumble-bee is surprising and suggests intermittent behavioural demands for extreme flight performance supplemental to routine foraging.
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18

Chaffiol, A. "Prior classical olfactory conditioning improves odour-cued flight orientation of honey bees in a wind tunnel." Journal of Experimental Biology 208, no. 19 (October 1, 2005): 3731–37. http://dx.doi.org/10.1242/jeb.01796.

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19

Vieira, Karine Munck, Paula Netto, Danielle L. A. S. Amaral, Sarah Silva Mendes, Lívia Cabral Castro, and Fábio Prezoto. "Nesting stingless bees in urban areas: a reevaluation after eight years." Sociobiology 63, no. 3 (October 25, 2016): 976. http://dx.doi.org/10.13102/sociobiology.v63i3.778.

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Studies of nesting ecology have proven to be extremely important for stingless bee conservation. These studies have rarely been conducted in urban landscapes, and even fewer have compared species diversity and abundances over time. We surveyed native stingless bee nests at the Federal University of Juiz de Fora campus in Minas Gerais, southeastern Brazil, from May 2008 to April 2009. We recorded the number of nests, nest height, species diversity, and nest substrate type (i.e., natural or artificial). We compared our results to those of a similar survey carried out in the same location eight years prior (2000/2001) in order to evaluate how urban expansion on campus has influenced the Meliponini bee community. Stingless bee abundance and richness were greater in the second survey. The use of natural substrates decreased, while the use of artificial substrates increased. This suggests that the increase in man-made structures on the UFJF campus has provided favorable sites for establishment of some stingless bee species.
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20

Warkentin, Dennis. "Larvicide for Beet Armyworm, 1988." Insecticide and Acaricide Tests 14, no. 1 (January 1, 1989): 321. http://dx.doi.org/10.1093/iat/14.1.321.

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Abstract Larvae from a resident colony reared on artificial diet were preconditioned on clean chrysanthemum foliage for at least 24 h prior to the bioassay. Fresh foliage was dipped in treatment dilutions and allowed to air dry before presentation to larvae. Each dilution contained Plyac at 4 fl oz/100 gal. Bioassays were performed in 1-oz plastic creamer cups with plastic snap lids, 1 larva/cup. A section of moist filter paper was included in each cup to maintain humidity. There were 6 replicate groups of 10 cups/treatment. The experiment was repeated for second and fourth instars. Three posttreatment evaluations were made at 24-h intervals.
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21

Hancock, Dave. "Primary Care Networks: What has been learned so far?" Practice Management 31, no. 2 (February 2, 2021): 22–26. http://dx.doi.org/10.12968/prma.2021.31.2.22.

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A rapid evaluation study into the development of Primary Care Networks in England has found a need for greater engagement at all levels, increased leadership and management capacity and clarification of roles post Covid-19
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22

Zakharov, Yu D., M. S. Arkhangelsky, N. G. Zverkov, I. V. Borisov, and A. M. Popov. "Age of beds with ichthyosaur Tholodus in South Primorye." Russian Journal of Pacific Geology 9, no. 5 (September 2015): 390–97. http://dx.doi.org/10.1134/s1819714015050073.

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23

Deschamps, Philippe. "Primary endosymbiosis: have cyanobacteria and Chlamydiae ever been roommates?" Acta Societatis Botanicorum Poloniae 83, no. 4 (2014): 291–302. http://dx.doi.org/10.5586/asbp.2014.048.

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Eukaryotes acquired the ability to process photosynthesis by engulfing a cyanobacterium and transforming it into a genuine organelle called the plastid. This event, named primary endosymbiosis, occurred once more than a billion years ago, and allowed the emergence of the Archaeplastida, a monophyletic supergroup comprising the green algae and plants, the red algae and the glaucophytes. Of the other known cases of symbiosis between cyanobacteria and eukaryotes, none has achieved a comparable level of cell integration nor reached the same evolutionary and ecological success than primary endosymbiosis did. Reasons for this unique accomplishment are still unknown and difficult to comprehend. The exploration of plant genomes has revealed a considerable amount of genes closely related to homologs of Chlamydiae bacteria, and probably acquired by horizontal gene transfer. Several studies have proposed that these transferred genes, which are mostly involved in the functioning of the plastid, may have helped the settlement of primary endosymbiosis. Some of these studies propose that Chlamydiae and cyanobacterial symbionts coexisted in the eukaryotic host of the primary endosymbiosis, and that Chlamydiae provided solutions for the metabolic symbiosis between the cyanobacterium and the host, ensuring the success of primary endosymbiosis. In this review, I present a reevaluation of the contribution of Chlamydiae genes to the genome of Archaeplastida and discuss the strengths and weaknesses of this tripartite model for primary endosymbiosis.
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Perry, G. A., B. L. Perry, J. A. Walker, C. L. Wright, R. R. Salverson, and H. H. Patterson. "Evaluation of prior grazing experience on reproductive performance in beef heifers." Professional Animal Scientist 29, no. 6 (December 2013): 595–600. http://dx.doi.org/10.15232/s1080-7446(15)30290-4.

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25

Larson, Nicholas R., Scott T. O’Neal, Ulrich R. Bernier, Jeffrey R. Bloomquist, and Troy D. Anderson. "Terpenoid-Induced Feeding Deterrence and Antennal Response of Honey Bees." Insects 11, no. 2 (January 23, 2020): 83. http://dx.doi.org/10.3390/insects11020083.

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Multiple interacting stressors negatively affect the survival and productivity of managed honey bee colonies. Pesticides remain a primary concern for beekeepers, as even sublethal exposures can reduce bee immunocompetence, impair navigation, and reduce social communication. Pollinator protection focuses on pesticide application guidelines; however, a more active protection strategy is needed. One possible approach is the use of feeding deterrents that can be delivered as an additive during pesticide application. The goal of this study was to validate a laboratory assay designed to rapidly screen compounds for behavioral changes related to feeding or feeding deterrence. The results of this investigation demonstrated that the synthetic Nasonov pheromone and its terpenoid constituents citral, nerol, and geraniol could alter feeding behavior in a laboratory assay. Additionally, electroantennogram assays revealed that these terpenoids elicited some response in the antennae; however, only a synthetic Nasonov pheromone, citral, and geraniol elicited responses that differed significantly from control and vehicle detections.
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26

Tulaczyk, Slawek M., and Neil T. Foley. "The role of electrical conductivity in radar wave reflection from glacier beds." Cryosphere 14, no. 12 (December 8, 2020): 4495–506. http://dx.doi.org/10.5194/tc-14-4495-2020.

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Abstract. We have examined a general expression giving the specular reflection coefficient for a radar wave approaching a reflecting interface with normal incidence. The reflecting interface separates two homogeneous isotropic media, the properties of which are fully described by three scalar quantities: dielectric permittivity, magnetic permeability, and electrical conductivity. The derived relationship indicates that electrical conductivity should not be neglected a priori in glaciological investigations of subglacial materials and in ground-penetrating radar (GPR) studies of saturated sediments and bedrock, even at the high end of typical linear radar frequencies used in such investigations (e.g., 100–400 MHz). Our own experience in resistivity surveying in Antarctica, combined with a literature review, suggests that a wide range of geologic materials can have electrical conductivity that is high enough to significantly impact the value of radar reflectivity. Furthermore, we have given two examples of prior studies in which inclusion of electrical conductivity in calculation of the radar bed reflectivity may provide an explanation for results that may be considered surprising if the impact of electrical conductivity on radar reflection is neglected. The commonly made assumption that only dielectric permittivity of the two media needs to be considered in interpretation of radar reflectivity can lead to erroneous conclusions.
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27

Narain, Devika, Robert J. van Beers, Jeroen B. J. Smeets, and Eli Brenner. "Sensorimotor priors in nonstationary environments." Journal of Neurophysiology 109, no. 5 (March 1, 2013): 1259–67. http://dx.doi.org/10.1152/jn.00605.2012.

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In the course of its interaction with the world, the human nervous system must constantly estimate various variables in the surrounding environment. Past research indicates that environmental variables may be represented as probabilistic distributions of a priori information (priors). Priors for environmental variables that do not change much over time have been widely studied. Little is known, however, about how priors develop in environments with nonstationary statistics. We examine whether humans change their reliance on the prior based on recent changes in environmental variance. Through experimentation, we obtain an online estimate of the human sensorimotor prior (prediction) and then compare it to similar online predictions made by various nonadaptive and adaptive models. Simulations show that models that rapidly adapt to nonstationary components in the environments predict the stimuli better than models that do not take the changing statistics of the environment into consideration. We found that adaptive models best predict participants' responses in most cases. However, we find no support for the idea that this is a consequence of increased reliance on recent experience just after the occurrence of a systematic change in the environment.
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Silva, Fabyano Fonseca e., Thelma Sáfadi, Joel Augusto Muniz, Guilherme Jordão Magalhães Rosa, Luiz Henrique de Aquino, Gerson Barreto Mourão, and Carlos Henrique Osório Silva. "Bayesian analysis of autoregressive panel data model: application in genetic evaluation of beef cattle." Scientia Agricola 68, no. 2 (April 2011): 237–45. http://dx.doi.org/10.1590/s0103-90162011000200015.

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The animal breeding values forecasting at futures times is a relevant technological innovation in the field of Animal Science, since its enables a previous indication of animals that will be either kept by the producer for breeding purposes or discarded. This study discusses an MCMC Bayesian methodology applied to panel data in a time series context. We consider Bayesian analysis of an autoregressive, AR(p), panel data model of order p, using an exact likelihood function, comparative analysis of prior distributions and predictive distributions of future observations. The methodology was tested by a simulation study using three priors: hierarchical Multivariate Normal-Inverse Gamma (model 1), independent Multivariate Student's t Inverse Gamma (model 2) and Jeffrey's (model 3). Comparisons by Pseudo-Bayes Factor favored model 2. The proposed methodology was applied to longitudinal data relative to Expected Progeny Difference (EPD) of beef cattle sires. The forecast efficiency was around 80%. Regarding the mean width of the EPD interval estimation (95%) in a future time, a great advantage was observed for the proposed Bayesian methodology over usual asymptotic frequentist method.
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Markova, T. O., N. V. Repsh, M. V. Маslov, and S. E. Egorenchev. "PROBLEMS OF BEEKEEPING AND DISEASES OF BEES IN DALNERECHENSK REGION (PRIMORYE TERRITORY, RUSSIAN FAR EAST)." Vestnik Orenburgskogo gosudarstvennogo universiteta 192, no. 4 (2016): 79–82. http://dx.doi.org/10.25198/1814-6457-192-79.

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30

Orsi, Rebecca, Chris Lee, Marc Winokur, and Amanda Pearson. "Who’s Been Served and How?" Youth Violence and Juvenile Justice 16, no. 1 (July 18, 2017): 3–17. http://dx.doi.org/10.1177/1541204017721614.

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Child welfare systems were created to protect maltreated children. However, adolescents today can be involved with child welfare for reasons other than maltreatment, including behavior issues. Such youth are also commonly involved in the youth corrections system. This study examines youth characteristics and risk factors which predict attaining permanency at case closure for youth involved in child welfare primarily for behavioral reasons. The sample consists of 5,691 youth aged 10–17 served in Colorado between 2007 and 2013. A multinomial logit model identified predictors of nonpermanent outcomes and of placement with return home, compared to remaining home throughout case involvement. Results show that the following characteristics and risks have a positive relationship with nonpermanent outcomes: longer case duration, prior child welfare placement, felony involvement, crimes against persons or property, truancy, running away, and gang membership. Services provided by the child welfare system are negatively related to nonpermanent outcomes.
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31

Qi, Jinyi. "Comparison of Lesion Detection and Quantification in MAP Reconstruction with Gaussian and Non-Gaussian Priors." International Journal of Biomedical Imaging 2006 (2006): 1–10. http://dx.doi.org/10.1155/ijbi/2006/87567.

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Statistical image reconstruction methods based on maximum a posteriori (MAP) principle have been developed for emission tomography. The prior distribution of the unknown image plays an important role in MAP reconstruction. The most commonly used prior are Gaussian priors, whose logarithm has a quadratic form. Gaussian priors are relatively easy to analyze. It has been shown that the effect of a Gaussian prior can be approximated by linear filtering a maximum likelihood (ML) reconstruction. As a result, sharp edges in reconstructed images are not preserved. To preserve sharp transitions, non-Gaussian priors have been proposed. However, their effect on clinical tasks is less obvious. In this paper, we compare MAP reconstruction with Gaussian and non-Gaussian priors for lesion detection and region of interest quantification using computer simulation. We evaluate three representative priors: Gaussian prior, Huber prior, and Geman-McClure prior. We simulate imaging a prostate tumor using positron emission tomography (PET). The detectability of a known tumor in either a fixed background or a random background is measured using a channelized Hotelling observer. The bias-variance tradeoff curves are calculated for quantification of the total tumor activity. The results show that for the detection and quantification tasks, the Gaussian prior is as effective as non-Gaussian priors.
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Cinegaglia, Naiara Costa, Paulo Ricardo Oliveira Bersano, Maria José Abigail Mendes Araújo, Michelle Cristiane Búfalo, and José Maurício Sforcin. "Anticancer Effects of Geopropolis Produced by Stingless Bees on Canine Osteosarcoma CellsIn Vitro." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/737386.

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Geopropolis is produced by indigenous stingless bees from the resinous material of plants, adding soil or clay. Its biological properties have not been investigated, such as propolis, and herein its cytotoxic action on canine osteosarcoma (OSA) cells was evaluated. OSA is a primary bone neoplasm diagnosed in dogs being an excellent modelin vivoto study human OSA. spOS-2 primary cultures were isolated from the tumor of a dog with osteosarcoma and incubated with geopropolis, 70% ethanol (geopropolis solvent), and carboplatin after 6, 24, 48, and 72 hours. Cell viability was analyzed by the crystal violet method. Geopropolis was efficient against canine OSA cells in a dose- and time-dependent way, leading to a distinct morphology compared to control. Geopropolis cytotoxic action was exclusively due to its constituents since 70% ethanol (its solvent) had no effect on cell viability. Carboplatin had no effect on OSA cells. Geopropolis exerted a cytotoxic effect on canine osteosarcoma, and its introduction as a possible therapeutic agentin vivocould be investigated, providing a new contribution to OSA treatment.
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Lechantre, Amandine, Ayrton Draux, Hoa-Ai Béatrice Hua, Denis Michez, Pascal Damman, and Fabian Brau. "Essential role of papillae flexibility in nectar capture by bees." Proceedings of the National Academy of Sciences 118, no. 19 (April 30, 2021): e2025513118. http://dx.doi.org/10.1073/pnas.2025513118.

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Many bees possess a tongue resembling a brush composed of a central rod (glossa) covered by elongated papillae, which is dipped periodically into nectar to collect this primary source of energy. In vivo measurements show that the amount of nectar collected per lap remains essentially constant for sugar concentrations lower than 50% but drops significantly for a concentration around 70%. To understand this variation of the ingestion rate with the sugar content of nectar, we investigate the dynamics of fluid capture by Bombus terrestris as a model system. During the dipping process, the papillae, which initially adhere to the glossa, unfold when immersed in the nectar. Combining in vivo investigations, macroscopic experiments with flexible rods, and an elastoviscous theoretical model, we show that the capture mechanism is governed by the relaxation dynamics of the bent papillae, driven by their elastic recoil slowed down through viscous dissipation. At low sugar concentrations, the papillae completely open before the tongue retracts out of nectar and thus, fully contribute to the fluid capture. In contrast, at larger concentrations corresponding to the drop of the ingestion rate, the viscous dissipation strongly hinders the papillae opening, reducing considerably the amount of nectar captured. This study shows the crucial role of flexible papillae, whose aspect ratio determines the optimal nectar concentration, to understand quantitatively the capture of nectar by bees and how physics can shed some light on the degree of adaptation of a specific morphological trait.
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34

Cao, Huazhen, Tao Yu, Xiaoshun Zhang, Bo Yang, and Yaxiong Wu. "Reactive Power Optimization of Large-Scale Power Systems: A Transfer Bees Optimizer Application." Processes 7, no. 6 (May 31, 2019): 321. http://dx.doi.org/10.3390/pr7060321.

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A novel transfer bees optimizer for reactive power optimization in a high-power system was developed in this paper. Q-learning was adopted to construct the learning mode of bees, improving the intelligence of bees through task division and cooperation. Behavior transfer was introduced, and prior knowledge of the source task was used to process the new task according to its similarity to the source task, so as to accelerate the convergence of the transfer bees optimizer. Moreover, the solution space was decomposed into multiple low-dimensional solution spaces via associated state-action chains. The transfer bees optimizer performance of reactive power optimization was assessed, while simulation results showed that the convergence of the proposed algorithm was more stable and faster, and the algorithm was about 4 to 68 times faster than the traditional artificial intelligence algorithms.
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35

Medina-Britos, M. A., A. M. Richardson, G. C. Lamb, B. A. Hensley, T. J. Marple, Jeffrey S. Stevenson, and Sandra K. Johnson. "Ovulation synchronization with progestins prior to a Cosynch protocol in beef cows." Kansas Agricultural Experiment Station Research Reports, no. 1 (January 1, 2001): 9–11. http://dx.doi.org/10.4148/2378-5977.1754.

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36

Hinton, M. H., W. R. Hudson, and G. C. Mead. "The bacteriological quality of British beef 1. Carcasses sampled prior to chilling." Meat Science 50, no. 2 (October 1998): 265–71. http://dx.doi.org/10.1016/s0309-1740(98)00047-3.

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37

Yang, A., M. J. Brewster, S. L. Beilken, M. C. Lanari, D. G. Taylor, and R. K. Tume. "Warmed-Over Flavor and Lipid Stability of Beef: Effects of Prior Nutrition." Journal of Food Science 67, no. 9 (November 2002): 3309–13. http://dx.doi.org/10.1111/j.1365-2621.2002.tb09584.x.

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38

McDaneld, Tara G., Larry A. Kuehn, and John W. Keele. "Microbiome of the upper nasal cavity of beef calves prior to weaning12." Journal of Animal Science 97, no. 6 (April 10, 2019): 2368–75. http://dx.doi.org/10.1093/jas/skz119.

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39

Postulkova, Michaela, David Riveros-Galan, Karla Cordova-Agiular, Kamila Zitkova, Hubert Verachtert, Guy Derdelinckx, Pavel Dostalek, Marek C. Ruzicka, and Tomas Branyik. "Technological possibilities to prevent and suppress primary gushing of beer." Trends in Food Science & Technology 49 (March 2016): 64–73. http://dx.doi.org/10.1016/j.tifs.2015.12.006.

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40

KUCHIDA, Keigo, Mio UEDA, Keisuke OKAMOTO, Mitsuyoshi SUZUKI, Shunzo MIYOSHI, and Toru TSURUTA. "Primary Investigation of Evaluating Beef Meat Color Using Computer Monitor." Nihon Chikusan Gakkaiho 73, no. 4 (2002): 521–28. http://dx.doi.org/10.2508/chikusan.73.521.

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41

Ashley Jefferson, J., and Stuart J. Shankland. "Has the circulating permeability factor in primary FSGS been found?" Kidney International 84, no. 2 (August 2013): 235–38. http://dx.doi.org/10.1038/ki.2013.204.

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42

Okuyan, Samet, and Paul Cross. "The Effects of Co-Enzyme Q10 and Caffeine on Morphometric Characteristics of Queen Honey Bees." Turkish Journal of Agriculture - Food Science and Technology 9, no. 2 (February 23, 2021): 321–25. http://dx.doi.org/10.24925/turjaf.v9i2.321-325.3903.

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Honey bee queen quality is a critical factor of colony performance. Indications of such qualities can manifest themselves through morphological traits such as wet weight and thorax width. Improving such characteristics is driven in part by nutritional provision in queen-cell-builder hives. We investigated the potential to improve queen quality by adding coenzyme Q10 (endogenous antioxidant) and caffeine (central nervous system stimulator) to feeder syrup in queen-cell-builder colonies for 15 and 20 days prior to grafting, two sets of queens were reared. We recorded subsequent wet weight, body length, head width and length, thorax and wing width and length, and spermathecae diameter. The queen-cell acceptance rate was not affected by either treatment or graft period. Coenzyme Q10 increased wet weight, body and wing length in the first graft, and thorax width, wing length and spermathecae diameter in the second graft. The caffeine treatment increased head and thorax length in first graft and thorax width in the second. A mix of the two substances (coenzyme Q10 and caffeine) increased head width in the first graft and spermathecae diameter in the second graft. This study suggests that the application of coenzyme Q10 to cell-builder colonies at least 15 days prior to grafting can increase reared wet weight (the most significant quality indicator) and thorax width of queen bees.
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43

Warkentin, D., M. Harris, and J. Begley. "Bendiocarb Screening Against Beet Armyworm, 1987." Insecticide and Acaricide Tests 13, no. 1 (January 1, 1988): 349–50. http://dx.doi.org/10.1093/iat/13.1.349b.

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Abstract Test insects were reared on artificial diet in a laboratory colony to third and fourth instars. To assess contact toxicity, larvae were placed in Petri dishes, sprayed with their respective treatment dilutions using a hand-held atomizer, then transferred to individual 1-oz creamer cups containing fresh diet and sealed with paper-insert lids. For the leaf-residue test, chrysanthemum leaves were dipped in treatment dilutions and allowed to air dry; larvae were introduced into individual creamer cups containing treated foliage and a section of moist filter paper. At each treatment level there were 5 replicate sets of 10 larvae/set. Mean percent mortalities were evaluated at 2-day intervals, and data were transformed by arcsin p prior to 1-way analysis of variance.
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44

Newbury, Colin. "Technology, Capital, and Consolidation: The Performance of De Beers Mining Company Limited, 1880–1889." Business History Review 61, no. 1 (1987): 1–42. http://dx.doi.org/10.2307/3115773.

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In this article, Dr. Newbury focuses on the technical and financial reasons for amalgamation at the Kimberley mines in South Africa, drawing on primary records to account for the rise of De Beers as the world's major diamond mining company in the 1880s. He finds that prior experience in local government and on the mining boards prepared company directors for competition in joint stock enterprise, while differences in production policies and performance influenced the pattern of mergers within and among the four Kimberley mines. De Beers's close relationship with diamond merchants and private banks in London, particularly N. M. Rothschild & Sons, was central to its position as a prime mover toward consolidation. Dr. Newbury views De Beers as a firm that relied for its success less on its renowned chairman, Cecil J. Rhodes, than on a combined managerial expertise that reflected the interests of both mining producers and merchant buyers.
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45

Patten, Kim, Rod Macfarlane, and Dan Mayer. "174 USING FERAL AND COMMERCIAL BUMBLE BEES FOR POLLINATION OF CRANBERRIES AND PEARS." HortScience 29, no. 5 (May 1994): 453g—454. http://dx.doi.org/10.21273/hortsci.29.5.453g.

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The pollination of cranberries and pears by honey bees is often inadequate. The pollination efficacy of feral (Bombus spp.) and/or commercial bumble bees was evaluated for these crops. Preliminary evaluation of commercial B. vosnesenskii and B. occidentalis hives indicated poor forage activity on pears, but good activity on cranberries. Hive stocking densities of B. occidentalis on cranberries required to match feral Bombus populations was 8-10 hive/ha. Hives required 1-2 weeks in the field prior to full bloom to achieve suitable forage density during bloom. Parasitism of commercial hives by wax moth and bumble bee brood fly was common. Commercial colonies did not appear to be cost effective at this time. Only short-tongued feral Bombus species foraged on cranberries. Acceptance of artificial domiciles by these species was poor. Enhancing feral populations required provision of supplemental food sources and improved nesting habitat. Management of alternative food resources for feral bumble bees will be discussed.
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46

Woessner, Mary, Mitch D. VanBruggen, Carl F. Pieper, Richard Sloane, William E. Kraus, Andrew J. Gow, and Jason D. Allen. "Beet the Best?" Circulation Research 123, no. 6 (August 31, 2018): 654–59. http://dx.doi.org/10.1161/circresaha.118.313131.

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Rationale: A primary goal of therapy for patients with peripheral artery disease (PAD) and intermittent claudication is increased ambulatory function. Supervised exercise rehabilitation was recently shown to confer superior walking benefits to pharmacological or surgical interventions. Increases in plasma inorganic nitrite, via oral nitrate, have been shown to increase exercise performance in both human and animal models, especially in hypoxic conditions. Objective: To determine whether a 36-session exercise rehabilitation program while consuming oral inorganic nitrate (4.2 mmol concentrated beetroot juice) would produce superior benefits over exercise plus placebo in pain-free walking and markers of increased skeletal muscle perfusion in patients with PAD and intermittent claudication. Methods and Results: This was a randomized, double-blind, per-protocol study design. After the 12-week protocol, claudication onset time on a maximal treadmill test increased by 59.2±57.3 s for the exercise plus placebo group (n=13) and by 180.3±46.6 s for the exercise plus beetroot juice group (n=11; P ≤0.05). This produced a between treatment medium to large standardized effect size (Cohen d) of 0.62 (95% CI, −0.23 to +1.44). The data for 6-minute walk distance showed a similar pattern with increases of 24.6±12.1 and 53.3±19.6 m ( P ≤0.05) in the exercise plus placebo and exercise plus beetroot juice groups, respectively. Measures of gastrocnemius perfusion, including ankle-brachial index, peak reactive hyperemic blood flow, and tissue deoxygenation characteristics, during exercise (assessed my near-infrared spectroscopy) all changed significantly for the exercise plus beetroot juice group with moderate-to-large effect sizes over exercise plus placebo changes. Conclusions: Although it is premature to speculate on overall clinical utility of a nitrate-based therapy for PAD, this early pilot study evidence is encouraging. Specifically, our data suggests that increasing plasma nitrite before exercise may allow PAD subjects to train with less pain, at higher workloads for longer durations at each training session, thereby maximizing the beneficial peripheral vascular and skeletal muscle adaptations. Clinical Trial Registration: URL: http://www.clinicaltrials.gov . Unique identifier: NCT01684930 and NCT01785524.
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47

Bielik, P., J. Pokrivčák, A. Qineti, and N. Pokrivčáková. "The spillover effect of foreign direct investment – the case of Slovak beer and malt production sector ." Agricultural Economics (Zemědělská ekonomika) 52, No. 8 (February 17, 2012): 347–52. http://dx.doi.org/10.17221/5033-agricecon.

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The paper deals with the FDI spillover effects in production of beer and malt in Slovakia. Malt producers have a dominant position in the market. The use of the almost monopsonistic power of malt producers is constrained the by low asset specificity of primary producers of barley, other outlets for the disposal of barley (export), and demand for high quality of malt from malt producers. Because of high dependence of malt producers for high quality and reliable deliveries of barley, malt producers provide a significant assistance of primary farmers.&nbsp;
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48

Thomson, James D. "Reversal of apparent feeding preferences of bumble bees by aggression from Vespula wasps." Canadian Journal of Zoology 67, no. 10 (October 1, 1989): 2588–91. http://dx.doi.org/10.1139/z89-364.

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In field experiments, the nectar and pollen levels of Aralia hispida inflorescences were independently manipulated. In the absence of Vespula spp., Bombus spp. workers (the primary pollinators) appeared to prefer nectar-enriched inflorescences, learning their locations and visiting them at a higher rate, but did not respond to variation in pollen. In the presence of Vespula, however, Bombus appeared to prefer inflorescences with more pollen, showing no response to nectar variation. Vespula responded strongly to nectar level, aggressively patrolling the nectar-enriched plants and preventing Bombus from feeding.
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49

Green, Linda V. "How Many Hospital Beds?" INQUIRY: The Journal of Health Care Organization, Provision, and Financing 39, no. 4 (November 2002): 400–412. http://dx.doi.org/10.5034/inquiryjrnl_39.4.400.

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For many years, average bed occupancy level has been the primary measure that has guided hospital bed capacity decisions at both policy and managerial levels. Even now, the common wisdom that there is an excess of beds nationally has been based on a federal target of 85% occupancy that was developed about 25 years ago. This paper examines data from New York state and uses queueing analysis to estimate bed unavailability in intensive care units (ICUs) and obstetrics units. Using various patient delay standards, units that appear to have insufficient capacity are identified. The results indicate that as many as 40% of all obstetrics units and 90% of ICUs have insufficient capacity to provide an appropriate bed when needed. This contrasts sharply with what would be deduced using standard average occupancy targets. Furthermore, given the model's assumptions, these estimates are likely to be conservative. These findings illustrate that if service quality is deemed important, hospitals need to plan capacity based on standards that reflect the ability to place patients in appropriate beds in a timely fashion rather than on target occupancy levels. Doing so will require the collection and analysis of operational data—such as demands for and use of beds, and patient delays—which generally are not available.
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50

Meza-Junco, Judith, Aldo J. Montano-Loza, Mang Ma, Winnie Wong, Michael B. Sawyer, and Vincent G. Bain. "Cholangiocarcinoma: Has There been Any Progress?" Canadian Journal of Gastroenterology 24, no. 1 (2010): 52–57. http://dx.doi.org/10.1155/2010/704759.

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Cholangiocarcinoma is the second most common primary hepatic tumour after hepatocellular carcinoma. Primary sclerosing cholangitis is one of the most commonly recognized risk factors for cholangiocarcinoma; however, approximately 90% of patients have no identifiable risk factors. Extrahepatic type is its most common presentation. Cholangiocarcinoma is considered to be a devastating disease, with a poor survival rate and few therapeutic options. Although surgical resection has been considered the best treatment option for localized cholangiocarcinoma, local recurrences of this cancer are very common, and imply persistent micrometastatic disease in lymph nodes or at surgical margins, even after extended surgical resection. Consequently, the five-year survival rate after attempted curative resection is only 20% to 40%. Early studies of liver transplantation for cholangiocarcinoma did not show a survival benefit and, currently, this tumour is considered to be an absolute contraindication for liver transplantation in most transplant centres worldwide. Recently, neoadjuvant chemoradiation in combination with liver transplantation for highly selected patients with cholangiocarcinoma has shown impressive results, with five-year survival rates at approximately 76% to 82% – similar to other standard indications for liver transplantation, such as hepatocellular carcinoma or hepatitis C-induced cirrhosis. However, this success of liver transplantation applies to only a subset of patients and most of the data originated from a single centre. Wider application of this strategy, especially for patients with potentially resectable disease, will require validation by other centres.
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