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Journal articles on the topic 'Behavioral potential (BP)'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Li, Jun, Dongqing Huang, Wanchen Liao, Yulin Wang, Yibiao Liu, and Ping Luan. "Advanced Nanopharmaceutical Intervention for the Reduction of Inflammatory Responses and the Enhancement of Behavioral Outcomes in APP/PS1 Transgenic Mouse Models." Pharmaceutics 17, no. 2 (2025): 177. https://doi.org/10.3390/pharmaceutics17020177.

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Background: The excessive accumulation of Aβ plays a critical role in the development of Alzheimer’s disease. However, the therapeutic potential of drugs like curcumin is often limited by low biocompatibility and BBB permeability. In this study, we developed a nanomaterial, BP-PEG-Tar@Cur, which was designed to enhance the biocompatibility of (curcumin) Cur, target Aβ, and augment BBB permeability through near-infrared (NIR) photothermal effects. Methods: Soluble Aβ, ThT fluorescence, and Aβ depolymerization fluorescence experiments were conducted to evaluate the ability of BP-PEG-Tar@Cur to i

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Baiduc, Rachael R., Caitlin M. Berry, Katherine Lemons, and Eric A. Vance. "Electrocochleography and Auditory Brainstem Responses in Persons with Non-Optimal Blood Pressure." Journal of the American Academy of Audiology 32, no. 09 (2021): 576–87. http://dx.doi.org/10.1055/s-0041-1733970.

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Abstract Background Numerous cardiometabolic factors may underlie risk of hearing loss. Modifiable risk factors such as non-optimal blood pressure (BP) are of interest. Purpose To investigate early auditory evoked potentials (AEPs) in persons with nonoptimal BP. Research Design A cross-sectional nonexperimental study was performed. Study Sample Fifty-two adults (18–55 years) served as subjects. Individuals were classified as having optimal (systolic [S] BP < 120 and diastolic [D] BP < 80 mm Hg, n = 25) or non-optimal BP (SBP ≥=120 or DBP ≥=80 mm Hg or antihypertensive use, n = 27). Thirt

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Giuliano, Marika, Sandro Santa Paola, Eugenia Borgione, et al. "The 9 bp Deletion between the Mitochondrial COII and Lysine tRNA Genes in a Caucasian Population with Cognitive Disorders: An Observational Study." International Journal of Molecular Sciences 25, no. 19 (2024): 10826. http://dx.doi.org/10.3390/ijms251910826.

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The loss of one of the two copies of the 9 bp tandem repeat sequence (CCCCCTCTA) located in the small non-coding region between the cytochrome oxidase II (COII) and the lysine tRNA genes in human mtDNA has been reported to be polymorphic in Asian, Oceanian and Sub-Saharan African populations, but it has rarely been observed in Europe. In this study, we will evaluate the possible association between the MIC9D polymorphism and cognitive disorders. A genetic analysis of unrelated Sicilian patients with cognitive deficits was performed to identify the 9 bp deletion MIC9D polymorphism. The MIC9D po

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Ma, Wei-ni, Ming-mei Zhou, Xiao-jun Gou, et al. "Urinary Metabolomic Study of Chlorogenic Acid in a Rat Model of Chronic Sleep Deprivation Using Gas Chromatography-Mass Spectrometry." International Journal of Genomics 2018 (2018): 1–11. http://dx.doi.org/10.1155/2018/1361402.

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The urinary metabolomic study based on gas chromatography-mass spectrometry (GC-MS) had been developed to investigate the possible antidepressant mechanism of chlorogenic acid (CGA) in a rat model of sleep deprivation (SD). According to pattern recognition analysis, there was a clear separation among big platform group (BP), sleep deprivation group (SD), and the CGA (model + CGA), and CGA group was much closer to the BP group by showing a tendency of recovering towards BP group. Thirty-six significantly changed metabolites related to antidepressant by CGA were identified and used to explore th

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Cocca, Armando, Klaus Greier, Clemens Drenowatz, et al. "Relation between Physical Fitness Components and the Occurrence and Subjective Intensity of Back Pain in Secondary School Adolescents." Behavioral Sciences 12, no. 10 (2022): 353. http://dx.doi.org/10.3390/bs12100353.

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Despite the well documented benefits of physical fitness (PF) on general health, its role in back pain (BP) is still unclear. The objective of this study was to assess the association between different PF profiles and BP in a sample of adolescents. The study assessed PF and BP in a sample of 919 youth (age = 15.5 ± 1.3 years) from North and South Tyrol. A total of 531 participants (57.8%) reported no BP, whereas 4.7% (n = 43) reported severe BP. A two-step cluster analysis detected three main groups: the “less fit”, with significantly lower scores in all PF tests (p < 0.001); the “strong sp

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Vasquez, Kimberly, Andrea Ronning, Moufdi Naji, et al. "4114 A Community/Academic Partnership to Implement Nutritional and Social/Behavioral Interventions to reduce Hypertension among Seniors Aging in Place." Journal of Clinical and Translational Science 4, s1 (2020): 76. http://dx.doi.org/10.1017/cts.2020.248.

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OBJECTIVES/GOALS: The Rockefeller University CCTS, Clinical Directors Network (CDN), and Carter Burden Network (CBN) received a DHHS-Administration for Community Living Nutrition Innovation grant to test whether implementation of DASH-concordant meals and a program to enhance self-efficacy, could lower blood pressure among seniors aging in place. METHODS/STUDY POPULATION: CEnR-Nav model to engage stakeholders, enroll seniors age >60 yr., eating 4 meals a week at 2 CBN congregate meal sites; Advisory Committee to facilitate dissemination; menus aligned with Dietary Approaches to Stop Hyperte

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Chaikijurajai, Thanat, Luke J. Laffin, and Wai Hong Wilson Tang. "Artificial Intelligence and Hypertension: Recent Advances and Future Outlook." American Journal of Hypertension 33, no. 11 (2020): 967–74. http://dx.doi.org/10.1093/ajh/hpaa102.

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Abstract Prevention and treatment of hypertension (HTN) are a challenging public health problem. Recent evidence suggests that artificial intelligence (AI) has potential to be a promising tool for reducing the global burden of HTN, and furthering precision medicine related to cardiovascular (CV) diseases including HTN. Since AI can stimulate human thought processes and learning with complex algorithms and advanced computational power, AI can be applied to multimodal and big data, including genetics, epigenetics, proteomics, metabolomics, CV imaging, socioeconomic, behavioral, and environmental

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Ajayi, Simeon Ayo-Oluwa, and Olayemi Oluwatosin Akanji. "Efficacy of Mobile Health Apps in Blood Pressure Control in USA." International Journal of Multidisciplinary Research and Growth Evaluation 6, no. 4 (2025): 211–16. https://doi.org/10.54660/.ijmrge.2025.6.4.211-216.

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Hypertension remains a leading cause of cardiovascular disease and death in the United States. Despite the efficacy of treatments, a significant number of patients have poor control of blood pressure (BP) due to a lack of adherence, lack of self-monitoring, and limited accessibility of sustained-care services. Mobile health (mHealth) applications have shown potential interventions for helping with control of hypertension through reminders for medications, tracking of BP, educational instructions, and connectivity with providers. This systematic review aims to evaluate the efficacy of mobile he

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Ajayi, Simeon Ayo-Oluwa, and Olayemi Oluwatosin Akanji. "Efficacy of Mobile Health Apps in Blood Pressure Control in USA." International Journal of Multidisciplinary Research and Growth Evaluation 3, no. 5 (2022): 635–40. https://doi.org/10.54660/.ijmrge.2022.3.5.635-640.

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Hypertension remains a leading cause of cardiovascular disease and death in the United States. Despite the efficacy of treatments, a significant number of patients have poor control of blood pressure (BP) due to a lack of adherence, lack of self-monitoring, and limited accessibility of sustained-care services. Mobile health (mHealth) applications have shown potential interventions for helping with control of hypertension through reminders for medications, tracking of BP, educational instructions, and connectivity with providers. This systematic review aims to evaluate the efficacy of mobile he

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Sebastian, Celestine, Amy Costa, Christina McCrae, and Ashley Curtis. "0861 Beat Right, Sleep Tight: Pilot Study of Depression’s Role on Blood Pressure and Sleep in Older Adults with Insomnia." SLEEP 47, Supplement_1 (2024): A370. http://dx.doi.org/10.1093/sleep/zsae067.0861.

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Abstract Introduction Insomnia disorder and hypertension are common in aging adults, making older adults at increased risk for cardiovascular disease. A bidirectional relationship between insomnia symptoms and hypertension exists, but mechanisms underlying this association are not fully understood. Depressive symptoms have been linked to insomnia. Additionally, there is a known association between depression and hypertension, but investigations of non-invasive blood pressure metrics are limited, which limits conclusions regarding disease markers and potential targets for intervention. This pil

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Still, Carolyn H., Seunghee P. Margevicius, Jackson T. Wright, Suebarn Ruksakulpiwat, and Shirley M. Moore. "A Pilot Study Evaluating the Effects of a Technology-Based and Positive Psychological Training Intervention on Blood Pressure in African Americans With Hypertension." Journal of Primary Care & Community Health 12 (January 2021): 215013272110561. http://dx.doi.org/10.1177/21501327211056186.

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Behavioral interventions consolidating technology are underutilized and do not reach diverse populations such as African Americans with hypertension. This pilot study aimed to evaluate the effects of a theoretically derived, technology-based intervention in African Americans with hypertension. African Americans with hypertension (N = 18; age range 25-85; 72.22% females) were randomized to the technology-based plus positive psychological training (PPT) experimental group (n = 10) or the comparison group (n = 8) for 12 weeks. The technology-based intervention included analytic components (web-ba

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Michaeli, Jennia, Riham Smoom, Noa Serruya, et al. "Leukocyte Telomere Length Correlates with Extended Female Fertility." Cells 11, no. 3 (2022): 513. http://dx.doi.org/10.3390/cells11030513.

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Current social trends of delayed reproduction to the fourth and fifth decade of life call for a better understanding of reproductive aging. Demographic studies correlated late reproduction with general health and longevity. Telomeres, the protective ends of eukaryotic chromosomes, were implicated in various aging-associated pathologies and longevity. To examine whether telomeres are also associated with reproductive aging, we measured by Southern analysis the terminal restriction fragments (TRF) in leukocytes of women delivering a healthy infant following a spontaneous pregnancy at 43–48 years

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Moody, Danielle L. Beatty, Yue-Fang Chang, Elizabeth J. Pantesco, et al. "Everyday Discrimination Prospectively Predicts Blood Pressure Across 10 Years in Racially/Ethnically Diverse Midlife Women: Study of Women’s Health Across the Nation." Annals of Behavioral Medicine 53, no. 7 (2018): 608–20. http://dx.doi.org/10.1093/abm/kay069.

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Abstract Background Interpersonal discrimination is linked to greater risk for cardiovascular disease (CVD) and this association varies by race/ethnicity. Purpose To examine whether exposure to everyday discrimination prospectively predicts elevated blood pressure (BP), whether this association differs by race/ethnicity, and is mediated by adiposity indices. Methods Using data for 2,180 self-identified White, Black, Chinese, Japanese, and Hispanic participants from the Study of Women’s Health Across the Nation, we examined associations among exposure to (higher vs. lower) everyday discriminati

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Afshar, Sepideh, Sevda Lule, Gengyang Yuan, et al. "Longitudinal PET studies of mGluR5 in FXS using an FMR1 knockout mouse model." Translational Neuroscience 13, no. 1 (2022): 80–92. http://dx.doi.org/10.1515/tnsci-2022-0217.

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Abstract Fragile X syndrome (FXS) is a monogenic disorder characterized by intellectual disability and behavioral challenges. It is caused by aberrant methylation of the fragile X mental retardation 1 (FMR1) gene. Given the failure of clinical trials in FXS and growing evidence of a role of metabotropic glutamate subtype 5 receptors (mGluR5) in the pathophysiology of the disorder, we investigated mGluR5 function in FMR1 Knockout (FMR1-KO) mice and age- and sex-matched control mice using longitudinal positron emission tomography (PET) imaging to better understand the disorder. The studies were

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Kost, Rhonda, Dozene Guishard, Moufdi Naji, et al. "290 Implementing a Multi-Component Intervention to Reduce Hypertension Through DASH Diet Congregate Meals and Self-Measured BP (SMBP) at Two NYC Senior Centers." Journal of Clinical and Translational Science 6, s1 (2022): 50–51. http://dx.doi.org/10.1017/cts.2022.160.

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OBJECTIVES/GOALS: To test whether implementing DASH-aligned meals in a congregate meal program, combined with Self-Measured Blood Pressure (SMBP) monitoring, lowers systolic blood pressure in community-living seniors at two senior centers. Secondary Aims included cognitive and behavioral change, and attention to client preferences. METHODS/STUDY POPULATION: The Carter Burden Network (CBN) provides services and congregate meals to older adults in NYC, many with low income, and unmet health needs. Eligible participants at two CBN sites, aged 60 or older and consuming >4 congregate meals/week,

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Farajallah, Achmad, Pristina Tuti Wijayanti, Achmad Alfiyan, and Maria Ulfah. "Karakterisasi Ekson 4 Gen DRD4 pada Ayam Arab Tiara G15 dengan Tingkah Laku Feather Pecking." Jurnal Ilmu Pertanian Indonesia 29, no. 3 (2024): 430–34. http://dx.doi.org/10.18343/jipi.29.3.430.

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Feather pecking (FP) is a potentially fatal behavioral disorder in chickens. Various factors, including genetics such as DRD4 gene, affected this behavior. The Arab TIARA G15 chicken is a laying hen breed selected based on FP behavior. However, genetic selection linked to this FP as not yet been conducted. This study aimed to characterize the 4th exon of the DRD4 gene in Arab golden red TIARA G15 chickens and confirm its potential as an FP genetic marker. The study used 30 TIARA G15 chickens that were divided into three groups: high feather pecking (HFP) (n = 10), low feather pecking (LFP) (n

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Kennedy, Michael A., Ann D. Russell, and Tom P. Guilderson. "A Radiocarbon Chronology of Hunter-Gatherer Occupation from Bodega Bay, California, USA." Radiocarbon 47, no. 2 (2005): 265–93. http://dx.doi.org/10.1017/s0033822200019779.

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We present a Holocene radiocarbon chronology of hunter-gatherer occupation based on contemporaneous samples of charcoal and Mytilus californianus shell recovered from 7 archaeological sites near Bodega Bay, California, USA. A series of 127 14C ages reveals a chronological sequence that spans from 8940–110 cal BP (1 σ). This sequence serves as a foundation for the interpretation of behavioral change along the northern California coast over the last 9000 yr, including the adaptive strategies used by human foragers to colonize and inhabit coastal areas of this region. These 14C ages will also per

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Chen, Ruonan, Qingpo Chu, Chunyan Shen, et al. "Identification of Single Nucleotide Polymorphisms in Porcine MAOA Gene Associated with Aggressive Behavior of Weaned Pigs after Group Mixing." Animals 9, no. 11 (2019): 952. http://dx.doi.org/10.3390/ani9110952.

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Understanding the genetic background underlying the expression of behavioral traits has the potential to fasten the genetic progress for reduced aggressive behavior of pigs. The monoamine oxidase A (MAOA) gene is known as the “warrior” gene, as it has been previously linked to aggressive behavior in humans and livestock animals. To identify single nucleotide polymorphisms in porcine MAOA gene associated with aggressive behavior of pigs, a total of 500 weaned pigs were selected and mixed in 51 pens. In each pen, two aggressive and two docile pigs (a total of 204 pigs) were selected based on the

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Dimsdale, Joel E. "Coronary Heart Disease in Women: Personality and Stress-Induced Biological Responses." Annals of Behavioral Medicine 15, no. 2-3 (1993): 119–23. http://dx.doi.org/10.1093/abm/15.2-3.119.

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Abstract Studies of reactivity to stressors have generally focused only on men. Women may react to stressors with a different adrenergic and hormonal response, however one cannot be sure that this reflects biological differences or differences in task interpretation across the sexes. Men appear to respond to behavioral stressors with a greater increase in systolic blood pressure (BP). Hemodynamic reactivity (i.e. heart rate and BP) is probably not altered by phase of menstrual cycle. Hormonal and receptor responses to stressors may well be influenced by phase of menstrual cycle; the luteal pha

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Edington, D. W., and J. Park. "Application of a Prediction Model for Identification of Individuals at Diabetic Risk." Methods of Information in Medicine 43, no. 03 (2004): 273–81. http://dx.doi.org/10.1055/s-0038-1633868.

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SummaryAs a follow-up to our preceding paper, we attempted to extract features of health risk progression for diabetes in Sequential Multi Layered Perceptron (SMLP) via inverse processing of the learned structure. The time-varying risk progress was assessed with risk trajectory and conditional mixture model.Overall risk cut along with the prediction was stable over time and high body mass index (BMI) tops the health behavioral risks predicting the onset of diabetes. For the initial prediction, high BMI (obesity), high blood pressure (BP), high cholesterol, and diet in fatty food were significa

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Ralph, Martin R., Shu-qun Shi, Carl H. Johnson, et al. "Targeted modification of the Per2 clock gene alters circadian function in mPer2luciferase (mPer2Luc) mice." PLOS Computational Biology 17, no. 5 (2021): e1008987. http://dx.doi.org/10.1371/journal.pcbi.1008987.

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Modification of the Per2 clock gene in mPer2Luc reporter mice significantly alters circadian function. Behavioral period in constant dark is lengthened, and dissociates into two distinct components in constant light. Rhythms exhibit increased bimodality, enhanced phase resetting to light pulses, and altered entrainment to scheduled feeding. Mechanistic mathematical modelling predicts that enhanced protein interactions with the modified mPER2 C-terminus, combined with differential clock regulation among SCN subregions, can account for effects on circadian behavior via increased Per2 transcript

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Demay, L., P. M. Vasyliev, L. V. Koulakovska, D. V. Stupak, P. S. Shydlovskyi, and V. I. Belyaeva. "PALAEOLITHIC HUMAN SOCIETIES DURING THE UPPER PLENIGLACIAL THROUGHT THEIR RELATIONS WITH OTHER ANIMALS IN UKRAINIAN ARCHAEOLOGICAL SITES." Archaeology and Early History of Ukraine 37, no. 4 (2020): 82–93. http://dx.doi.org/10.37445/adiu.2020.04.06.

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The first part of the Upper Pleniglacial (around 26000—20000 BP) is characterized by a deterioration in weather conditions, which reached its peak during the Last Glacial Maximum. In the East European Plain, most of its lands were dominated by a periglacial steppe-tundra with the maximum extension of ice sheet in the North and permafrost. The different animal species had to adapt to these environments, also as human groups.The recent works realized in Ukraine permit to better understand the lifestyles of the Palaeolithic human groups, particularly their subsistence activities, the modalities o

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Zhang, Ruirui, Xiaoyue Lun, Yu Zhang, Yunhe Zhao, Xiuxiu Xu, and Zhengqun Zhang. "Characterization of Ionotropic Receptor Gene EnouIR25a in the Tea Green Leafhopper, Empoasca onukii Matsuda." Plants 12, no. 10 (2023): 2034. http://dx.doi.org/10.3390/plants12102034.

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Ionotropic receptors (IRs) play a central role in detecting chemosensory information from the environment and guiding insect behaviors and are potential target genes for pest control. Empoasca onukii Matsuda is a major pest of the tea plant Camellia sinensis (L.) O. Ktze, and seriously influences tea yields and quality. In this study, the ionotropic receptor gene EnouIR25a in E. onukii was cloned, and the expression pattern of EnouIR25a was detected in various tissues. Behavioral responses of E. onukii to volatile compounds emitted by tea plants were determined using olfactometer bioassay and

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Zaidi, Syed Kashif, Farid Ahmed, Heba Alkhatabi, Md Nasrul Hoda, and Muhammad Al-Qahtani. "Nebulization of Low-Dose S-Nitrosoglutathione in Diabetic Stroke Enhances Benefits of Reperfusion and Prevents Post-Thrombolysis Hemorrhage." Biomolecules 11, no. 11 (2021): 1587. http://dx.doi.org/10.3390/biom11111587.

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The COVID-19 pandemic has escalated the occurrence of hypoxia including thrombotic stroke worldwide, for which nitric oxide (NO) therapy seems very promising and translatable. Therefore, various modes/routes of NO-delivery are now being tested in different clinical trials for safer, faster, and more effective interventions against ischemic insults. Intravenous (IV) infusion of S-Nitrosoglutathione (GSNO), the major endogenous molecular pool of NO, has been reported to protect against mechanical cerebral ischemia-reperfusion (IR); however, it has been never tested in any kind of “clinically” re

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Wang, Shuo. "Machine Learning Approaches to Stock Index Prediction." Advances in Economics, Management and Political Sciences 176, no. 1 (2025): 135–40. https://doi.org/10.54254/2754-1169/2025.22100.

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In response to the stock market's volatile nature, this research examines stock index forecasting evolution from traditional econometric models to advanced machine learning techniques. Market volatility, influenced by economic conditions, investor sentiment, and market interconnectedness, often renders linear models inadequate. While fundamental, conventional methods like multiple regression and ARMA face limitations with non-linear, noisy data, prompting development of machine learning approaches such as BP neural networks, SVM, and attention-enhanced CNN-LSTM models. These advanced technique

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OSMAN, MOHAMED M. M., SHAABAN A. HEMEDA, ABEER A. I. HASSANIN, and WALAA A. HUSSEINY. "Polymorphism of Prolactin Gene and Its Association with Egg Production Trait in Four Commercial Chicken Lines." Journal of the Hellenic Veterinary Medical Society 68, no. 3 (2018): 391. http://dx.doi.org/10.12681/jhvms.15502.

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Broodiness is a behavioral trait observed in most common breeds of domestic fowl and due to its fundamental role in avian reproduction, it has been of great interest to poultry scientists, breeders and producers of hatching eggs. Prolactin gene (PRL) is generally accepted as crucial to the onset and maintenance of broodiness in birds and thus plays a crucial role in egg production. Therefore, the present study aimed to screen the Single Nucleotides Polymorphisms (SNPs) of prolactin gene in four commercial chicken lines namely Hubbard F15, Lohmann, Cobb500, and Avian48 using PCR and direct sequ

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Lauby, Samantha C., Hannah E. Lapp, Melissa Salazar, et al. "Postnatal maternal care moderates the effects of prenatal bisphenol exposure on offspring neurodevelopmental, behavioral, and transcriptomic outcomes." PLOS ONE 19, no. 6 (2024): e0305256. http://dx.doi.org/10.1371/journal.pone.0305256.

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Bisphenols (BP), including BPA and “BPA-free” structural analogs, are commonly used plasticizers that are present in many plastics and are known endocrine disrupting chemicals. Prenatal exposure to BPA has been associated with negative neurodevelopmental and behavioral outcomes in children and in rodent models. Prenatal BPA exposure has also been shown to impair postnatal maternal care provisioning, which can also affect offspring neurodevelopment and behavior. However, there is limited knowledge regarding the biological effects of prenatal exposure to bisphenols other than BPA and the interpl

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Mihevc, Matic, Majda Mori Lukančič, Črt Zavrnik, et al. "Impact of 12-Month mHealth Home Telemonitoring on Clinical Outcomes in Older Individuals With Hypertension and Type 2 Diabetes: Multicenter Randomized Controlled Trial." JMIR mHealth and uHealth 13 (May 29, 2025): e59733-e59733. https://doi.org/10.2196/59733.

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Abstract Background As the population ages, the prevalence of chronic diseases such as arterial hypertension (AH) and type 2 diabetes (T2D) is increasing, posing challenges for effective management in primary care settings. Although mobile health (mHealth) home telemonitoring offers promising support, evidence regarding its clinical impact on older patients is limited. Objective The objective of this paper was to evaluate the impact of 12-month telemonitoring on clinical outcomes in older individuals with AH and T2D compared to standard care in a primary care setting. Methods In a multicenter,

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Zhang, Ruirui, Xiaoyue Lun, Yunhe Zhao, et al. "RNAi-Mediated Interference with EonuGR1 Affects the Recognition of Phenylacetaldehyde by Empoasca onukii Matsuda (Hemiptera: Cicadellidae)." Agronomy 13, no. 9 (2023): 2221. http://dx.doi.org/10.3390/agronomy13092221.

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Empoasca onukii Matsuda is a primary pest of the tea plant Camellia sinensis (L.) O. Ktze that severely influences the production and quality of tea products. Gustatory receptors (GRs) are an indispensable part of the E. onukii chemosensory machinery as members of the G-protein coupled receptor family. Insect odor and gustatory receptors are consumingly sensitive and selective sensory receptors to search for foraging, mates, and spawning sites. In this study, the gustatory receptor EonuGR1 was cloned and analyzed bioinformatically, and the expression levels of EonuGR1 in diverse tissues of E.

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Liao, Yonghua, Junjie Liu, Jinyuan Zhang, et al. "Modeling Fragile X Syndrome: Characterizing Fmr1 Gene Knockout Mice across Genotype, Behavior, and Morphology." Neurological Sciences and Neurophysiology 41, no. 3 (2024): 139–52. http://dx.doi.org/10.4103/nsn.nsn_25_24.

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ABSTRACT Objective: Fragile X syndrome (FXS) is a hereditary condition resulting from dynamic mutations in the Fmr1 gene, leading to reduced or absent fragile X mental retardation protein (FMRP). Although molecular genetic diagnostics for FXS have advanced, there is currently a lack of effective clinical treatment. Hence, identifying a suitable FXS animal model is crucial for FXS therapeutic studies. This study primarily aims to evaluate whether Fmr1 mice display aberrant behaviors similar to those observed in human FXS patients, aiming to validate their feasibility as a model for FXS. Researc

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Audira, Gilbert, Sreeja Sarasamma, Jung-Ren Chen, et al. "Zebrafish Mutants Carrying Leptin a (lepa) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color Preference Dysregulation." International Journal of Molecular Sciences 19, no. 12 (2018): 4038. http://dx.doi.org/10.3390/ijms19124038.

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Leptin, a hormone secreted by peripheral adipose tissues, regulates the appetite in animals. Recently, evidence has shown that leptin also plays roles in behavioral response in addition to controlling appetite. In this study, we examined the potential function of leptin on non-appetite behaviors in zebrafish model. By using genome editing tool of Transcription activator-like effector nuclease (TALEN), we successfully knocked out leptin a (lepa) gene by deleting 4 bp within coding region to create a premature-translation stop. Morphological and appetite analysis showed the lepa KO fish display

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Gordon, Ross, Nadia Zainuddin, and Christopher Magee. "Unlocking the potential of branding in social marketing services: utilising brand personality and brand personality appeal." Journal of Services Marketing 30, no. 1 (2016): 48–62. http://dx.doi.org/10.1108/jsm-02-2015-0105.

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Purpose This paper aims to demonstrate the utility of branding theory for social marketing services. Specifically, this is to our knowledge the first to investigate brand personality (BP) and brand personality appeal (BPA) in a single study as predictors for consumer attitudes and intentions to engage with a service. Design/methodology/approach The associations between BP and BPA and their subsequent associations with attitudes and intentions are tested in two service types, i.e. a commercial marketing service (banking) and a social marketing service (health screening). This involved a cross-s

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Voelkel, Eva-Maria, Gerald Reiner, and Hans-Joachim Trappe. "Effects of music on behaviour and the cardiovascular system in animals and human beings." Music and Medicine 13, no. 1 (2021): 36–46. http://dx.doi.org/10.47513/mmd.v13i1.760.

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AbstractBackground Music plays an important role during life. However, there is little known whether music of different styles can directly alter behavioural patterns in animals or cardiovascular parameters in humans.Objective To study the potential effects of classical music (CL) and heavy metal (HM) in comparison to silence (S) on behavioural patterns or cardiovascular parameters blood pressure (BP), heart rate (HR).Method Behavioural patterns were examined in six German Large White pigs. More than 11.000 distinct singular behaviours were analyzed. Cortisol levels, heart rate and blood press

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Blodgett, Joanna, Matthew Ahmadi, Andrew Atkin, Annemarie Koster, Emmanuel Stamatakis, and Mark Hamer. "TWENTY-FOUR-HOUR MOVEMENT AND BLOOD PRESSURE: SIX PART COMPOSITIONAL DATA ANALYSIS STUDY FROM THE PROPASS CONSORTIUM." Innovation in Aging 8, Supplement_1 (2024): 78. https://doi.org/10.1093/geroni/igae098.0244.

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Abstract Physical activity has widely known benefits for cardiovascular health. However, the influence of movement across the entire 24-hour behavioural spectrum (e.g. sleeping, sedentarism, activity type, etc.) on blood pressure remains underexplored. This study investigated associations between free-living activities that comprise a 24-hour day and systolic and diastolic BP (SBP; DBP). Data from six cohorts within the Prospective Physical Activity, Sitting and Sleep consortium (ProPASS) consortium (n=14,761; mean age 54.2±9.6 years) were analysed. Using thigh-worn accelerometers, all activit

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Khamsaw, Pattarapol, Sarana Rose Sommano, Malaiporn Wongkaew, et al. "Banana Peel (Musa ABB cv. Nam Wa Mali-Ong) as a Source of Value-Adding Components and the Functional Properties of Its Bioactive Ingredients." Plants 13, no. 5 (2024): 593. http://dx.doi.org/10.3390/plants13050593.

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Banana peel (BP) is the primary by-product generated during banana processing which causes numerous environmental issues. This study examines the physical attributes, proximate analysis, glycoarray profiling, antioxidant abilities, and prebiotic activity of BP. The analysis demonstrated that carbohydrates constituted the primary components of BP and the glycoarray profiling indicated that BP contains multiple pectin and hemicellulose structures. BP also contained phenolic compounds, including (+)-catechin and gallic acid, flavonoid compounds, and antioxidant activities. BP demonstrated prebiot

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Efthimiou, Ioanna, Dimitris Vlastos, Vassilios Triantafyllidis, Antonios Eleftherianos, and Maria Antonopoulou. "Investigation of the Genotoxicological Profile of Aqueous Betula pendula Extracts." Plants 11, no. 20 (2022): 2673. http://dx.doi.org/10.3390/plants11202673.

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Betula pendula belongs to the Betulaceae family and is most common in the northern hemisphere. Various birch species have exhibited antimicrobial, antioxidant and anticancer properties. In the present study, we investigated the genotoxic and cytotoxic activity as well as the antigenotoxic potential against the mutagenic agent mitomycin-C (MMC) of two commercial products, i.e., a Betula pendula aqueous leaf extract product (BE) and a Betula pendula product containing aqueous extract of birch leaves at a percentage of 94% and lemon juice at a percentage of 6% (BP) using the cytokinesis block mic

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Berry, SL. "The Potential of Fossil Mammal Middens as Indicators of Vegetation History in Central Australia." Australian Journal of Botany 39, no. 3 (1991): 305. http://dx.doi.org/10.1071/bt9910305.

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The plant macrofossil contents of two fossil mammal middens were investigated. Midden MS was collected from near Mt Swan, 200 km north-east of Alice Springs in central Australia. The vegetation in this region is predominantly grassland scattered with low trees. Midden KS was collected from Kathleen Springs, 240 km west-south-west of Alice Springs. The flora in this locality is dominated by forbs and chenopods. Midden KS had a radiocarbon age of 1700 years BP at the top and 3500 years BP at the bottom. Most of the plant taxa in each midden were components in the flora of the vegetation zones cu

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Dumonceaux, Tim, Sathya Prakash Venglat, Kumuda Kushalappa, Gopalan Selvaraj, and Raju Datla. "Molecular and functional characterization of Brassica BREVIPEDICELLUS orthologs involved in inflorescence architectureThis paper is one of a selection of papers published in a Special Issue from the National Research Council of Canada – Plant Biotechnology Institute." Botany 87, no. 6 (2009): 604–15. http://dx.doi.org/10.1139/b09-026.

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The diversity of inflorescence architecture in angiosperms relates to attracting pollinators and allowing the effective dispersal of seeds. Molecular understanding of the genetic factors regulating inflorescence architecture from the model system of Arabidopsis could provide critical insights for addressing this developmental process/pathway in a closely related crop species like Brassica napus L. Towards this objective, we have isolated and characterized the orthologs of the homeobox gene BREVIPEDICELLUS (BP) in three Brassica species, B. napus (BnBP), Brassica rapa L. (BrBP), and Brassica ol

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Spikins, Penny, Jennifer C. French, Seren John-Wood, and Calvin Dytham. "Theoretical and Methodological Approaches to Ecological Changes, Social Behaviour and Human Intergroup Tolerance 300,000 to 30,000 BP." Journal of Archaeological Method and Theory 28, no. 1 (2021): 53–75. http://dx.doi.org/10.1007/s10816-020-09503-5.

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AbstractArchaeological evidence suggests that important shifts were taking place in the character of human social behaviours 300,000 to 30,000 years ago. New artefact types appear and are disseminated with greater frequency. Transfers of both raw materials and finished artefacts take place over increasing distances, implying larger scales of regional mobility and more frequent and friendlier interactions between different communities. Whilst these changes occur during a period of increasing environmental variability, the relationship between ecological changes and transformations in social beh

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Shelke, Rahul Gunvantrao, Rudra Prasad Banerjee, Babita Joshi, et al. "Chloroplast Genome of Lithocarpus dealbatus (Hook.f. & Thomson ex Miq.) Rehder Establishes Monophyletic Origin of the Species and Reveals Mutational Hotspots with Taxon Delimitation Potential." Life 12, no. 6 (2022): 828. http://dx.doi.org/10.3390/life12060828.

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There is phylogenetic ambiguity in the genus Lithocarpus and subfamily Quercoideae (Family: Fagaceae). Lithocarpus dealbatus, an ecologically important tree, is the dominant species among the Quercoideae in India. Although several studies have been conducted on the species’ regeneration and ecological and economic significance, limited information is available on its phylo-genomics. To resolve the phylogeny in Quercoideae, we sequenced and assembled the 161,476 bp chloroplast genome of L. dealbatus, which has a large single-copy section of 90,732 bp and a small single-copy region of 18,987 bp,

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KIM, Sang-Tae, Sang-Hun OH, and Jongsun PARK. "The complete chloroplast genome of Diarthron linifolium (Thymelaeaceae), a species found on a limestone outcrop in eastern Asia." Korean Journal of Plant Taxonomy 51, no. 4 (2021): 345–52. http://dx.doi.org/10.11110/kjpt.2021.51.4.345.

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Diarthron linifolium Turcz. is an annual herb usually found in sandy soil or limestone areas. Plants in the genus Diarthron are known to have toxic chemicals that may, however, be potentially useful as an anticancer treatment. Diarthron linifolium is a unique species among the species of the genus distributed in Korea. Here, we determine the genetic variation of D. linifolium collected in Korea with a full chloroplast genome and investigate its evolutionary status by means of a phylogenetic analysis. The chloroplast genome of Korean D. linifolium has a total length of 172,644 bp with four subr

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Buitrago-López, Carol, Kiruthiga G. Mariappan, Anny Cárdenas, Hagen M. Gegner, and Christian R. Voolstra. "The Genome of the Cauliflower Coral Pocillopora verrucosa." Genome Biology and Evolution 12, no. 10 (2020): 1911–17. http://dx.doi.org/10.1093/gbe/evaa184.

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Abstract Climate change and ocean warming threaten the persistence of corals worldwide. Genomic resources are critical to study the evolutionary trajectory, adaptive potential, and genetic distinctiveness of coral species. Here, we provide a reference genome of the cauliflower coral Pocillopora verrucosa, a broadly prevalent reef-building coral with important ecological roles in the maintenance of reefs across the Red Sea, the Indian Ocean, and the Pacific Ocean. The genome has an assembly size of 380,505,698 bp with a scaffold N50 of 333,696 bp and a contig N50 of 75,704 bp. The annotation of

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CHEN, XINGRU, SHAODE WU, ZELONG NIE, JUN WEN, and YING MENG. "Comparative analyses of complete plastid genomes of representative species of subfamily Convallarioideae (Asparagaceae)." Phytotaxa 638, no. 1 (2024): 20–32. http://dx.doi.org/10.11646/phytotaxa.638.1.2.

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Convallarioideae are a subfamily of Asparagaceae, a morphologically diverse group comprising seven tribes, i.e., Eriospermeae, Rusceae, Dracaeneae, Nolineae, Convallarieae, Ophiopogoneae and Polygonateae, and two genera unclassified to tribe. In this study, we conducted comparative plastid genome (plastome) analyses of seven species representing seven clades of the subfamily. The results showed that all plastomes exhibited standard conserved quadripartite structures with inverted repeats (26,261–26,522 bp) separated by a large single-copy region (83,007–85,692 bp) and a small single-copy regio

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Tomé, Luiz Marcelo Ribeiro, Felipe Ferreira da Silva, Paula Luize Camargos Fonseca, et al. "Hybrid Assembly Improves Genome Quality and Completeness of Trametes villosa CCMB561 and Reveals a Huge Potential for Lignocellulose Breakdown." Journal of Fungi 8, no. 2 (2022): 142. http://dx.doi.org/10.3390/jof8020142.

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Trametes villosa is a wood-decaying fungus with great potential to be used in the bioconversion of agro-industrial residues and to obtain high-value-added products, such as biofuels. Nonetheless, the lack of high-quality genomic data hampers studies investigating genetic mechanisms and metabolic pathways in T. villosa, hindering its application in industry. Herein, applying a hybrid assembly pipeline using short reads (Illumina HiSeq) and long reads (Oxford Nanopore MinION), we obtained a high-quality genome for the T. villosa CCMB561 and investigated its genetic potential for lignocellulose b

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Djaoudi, Kahina, France Van Wambeke, Aude Barani, et al. "Potential bioavailability of organic matter from atmospheric particles to marine heterotrophic bacteria." Biogeosciences 17, no. 24 (2020): 6271–85. http://dx.doi.org/10.5194/bg-17-6271-2020.

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Abstract. The surface ocean receives important amounts of organic carbon from atmospheric deposition. The degree of bioavailability of this source of organic carbon will determine its impact on the marine carbon cycle. In this study, the potential availability of dissolved organic carbon (DOC) leached from both desert dust and anthropogenic aerosols to marine heterotrophic bacteria was investigated. The experimental design was based on 16 d incubations, in the dark, of a marine bacterial inoculum into artificial seawater amended with water-soluble Saharan dust (D treatment) and anthropogenic (

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Xu, Su, Jianjun Cheng, Xiangchen Meng, Yan Xu, and Ying Mu. "Complete Genome and Comparative Genome Analysis of Lactobacillus reuteri YSJL-12, a Potential Probiotics Strain Isolated From Healthy Sow Fresh Feces." Evolutionary Bioinformatics 16 (January 2020): 117693432094219. http://dx.doi.org/10.1177/1176934320942192.

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Lactobacillus reuteri YSJL-12 was isolated from healthy sow fresh feces and used as probiotics additives previously. To investigate the genetic basis on probiotic potential and identify the genes in the strain, the complete genome of YSJL-12 was sequenced. Then comparative genome analysis on 9 strains of Lactobacillus reuteri was performed. The genome of YSJL-12 consisted of a circular 2,084,748 bp chromosome and 2 circular plasmids (51,906 and 15,134 bp). From among the 2065 protein-coding sequences (CDSs), the genes resistant to the environmental stress were identified. The function of COG (

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Chen, Sentao, Peng Shi, Qingkai Feng, et al. "A Novel C-Type Lectin and Its Potential Role in Feeding Selection in Ruditapes philippinarum." Fishes 8, no. 2 (2023): 62. http://dx.doi.org/10.3390/fishes8020062.

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In recent years, research on lectins is a hot topic in bivalve feeding choice studies. Ruditapes philippinarum are marine bivalves with important economic value. A new C-type lectin (Rpcl) from the manila clam was obtained and its potential role in feed selection was studied. Rpcl cDNA was 929 bp in length and had 720 bp of open reading frame. Rpcl encoded 235 amino acids, comprising a carbohydrate recognition domain (CRD) as well as an N-terminal signal peptide. Rpcl contained a conserved CRD disulfide bond including five cysteine residues (Cys125, Cys142, Cys213, Cys219, and Cys237) and the

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Kok, Hwee Chia, and Hock Lim Boon. "UNDERSTANDING OVEREXCITABILITIES OF PEOPLE WITH EXCEPTIONAL ABILITIES WITHIN THE FRAMEWORK OF COGNITION-CONATION-AFFECT-AND-SENSATION." European Journal of Education Studies 3, no. 6 (2017). https://doi.org/10.5281/zenodo.803406.

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People, young and old, with exceptional abilities, be they gifted, talented or savant, often manifest overexcitabilities (OEs) – innate intensities, heightened sensitivity and response to stimuli – that can impact positively or negatively or both on the developmental potential of an individual. The term <em>potential</em> refers to the human behavior (i.e., behavioral potential) that can be expressed in terms of thoughts (<strong>C</strong>ognition), actions (<strong>C</strong>onation), feelings (<strong>A</strong>ffect) and senses (<strong>S</strong>ensation), also known as CCAS model. This p

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Xia, Xi, Mei Ding, Jin-feng Xuan, et al. "Functional polymorphisms and transcriptional analysis in the 5′ region of the human serotonin receptor 1B gene (HTR1B) and their associations with psychiatric disorders." BMC Psychiatry 20, no. 1 (2020). http://dx.doi.org/10.1186/s12888-020-02906-4.

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Abstract Background The 5-hydroxytryptamine 1B receptor (5-HT1B) plays an essential role in the serotonin (5-HT) system and is widely involved in a variety of brain activities. HTR1B is the gene encoding 5-HT1B. Genome-wide association studies have shown that HTR1B polymorphisms are closely related to multiple mental and behavioral disorders; however, the functional mechanisms underlying these associations are unknown. This study investigated the effect of several HTR1B haplotypes on regulation of gene expression in vitro and the functional sequences in the 5′ regulatory region of HTR1B to det

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Wakeford, Alison, Jonathon A. Nye, Zachary A. Grieb, et al. "Sex influences the effects of social status on socioemotional behavior and serotonin neurochemistry in rhesus monkeys." Biology of Sex Differences 14, no. 1 (2023). http://dx.doi.org/10.1186/s13293-023-00562-3.

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Abstract Background Despite observed sex differences in the prevalence of stress-related psychiatric conditions, most preclinical and translational studies have only included male subjects. Therefore, it has not been possible to effectively assess how sex interacts with other psychosocial risk factors to impact the etiology and maintenance of stress-related psychopathology. One psychosocial factor that interacts with sex to impact risk for stress-related behavioral and physiological deficits is social dominance. The current study was designed to assess sex differences in the effects of social

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