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Journal articles on the topic 'Benefits and Risk Assessment'

Author: Grafiati

Published: 7 June 2025

Last updated: 16 July 2025

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1

Levitan, Bennett, Stephen C. Hadler, William Hurst, et al. "The Brighton collaboration standardized module for vaccine benefit-risk assessment." Vaccine 42, no. 4 (2024): 972–86. https://doi.org/10.1016/j.vaccine.2023.09.039.

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Vaccine Benefit-Risk (B-R) assessment consists of evaluating the benefits and risks of a vaccine and making a judgment whether the expected key benefits outweigh the potential key risks associated with its expected use. B-R supports regulatory and public health decision-making throughout the vaccine’s lifecycle. In August 2021, the Brighton Collaboration’s Benefit-Risk Assessment of VAccines by TechnolOgy (BRAVATO) Benefit-Risk Assessment Module working group was established to develop a standard module to support the planning, conduct and evaluation of structured B-R assessments f

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2

Ruddon, K. "Health Risk Assessment: What Are The Benefits?" JNCI Journal of the National Cancer Institute 80, no. 14 (1988): 1092–94. http://dx.doi.org/10.1093/jnci/80.14.1092-a.

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Poulter, NR. "Benefits and pitfalls of cardiovascular risk assessment." Journal of Human Hypertension 14, S2 (2000): S11—S16. http://dx.doi.org/10.1038/sj.jhh.1001071.

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Pomerantz, Rebecca G., David A. Lee, and Daniel M. Siegel. "Risk assessment in surgical patients: balancing iatrogenic risks and benefits." Clinics in Dermatology 29, no. 6 (2011): 669–77. http://dx.doi.org/10.1016/j.clindermatol.2011.08.012.

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Osborne, Vicki, Miranda Davies, Debabrata Roy, Francesco Tescione, and Saad A. W. Shakir. "Systematic benefit-risk assessment for buprenorphine implant: a semiquantitative method to support risk management." BMJ Evidence-Based Medicine 25, no. 6 (2020): 199–205. http://dx.doi.org/10.1136/bmjebm-2019-111295.

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BackgroundPrior to approval in the European Union, a systematic benefit-risk assessment was required to compare buprenorphine implant to sublingual buprenorphine as part of the license application to the European Medicines Agency.ObjectiveThe Benefit-Risk Action Team framework was used to describe the overall benefit-risk of buprenorphine implant in comparison to sublingual buprenorphine.Study selection/methodsA value tree of key benefits and risks related to the implant formulation of buprenorphine was constructed. Risk differences (RD) or reporting ORs (ROR) and corresponding 95% CIs were ca

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Miller, Franklin G. "Clinical equipoise and risk–benefit assessment." Clinical Trials 9, no. 5 (2012): 621–27. http://dx.doi.org/10.1177/1740774512450952.

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Clinical equipoise is widely regarded as an ethical requirement for the design and conduct of randomized controlled trials (RCTs). Underlying clinical equipoise is the norm that no patient should be randomized to treatment known (or believed by the expert clinical community) to be inferior to the established standard of care. This implies that patient–subjects should not be exposed to net risks in control groups of randomized trials – risks that are not compensated by the prospect of direct medical benefits from the control intervention. However, proponents of clinical equipoise have no moral

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Collins, LM. "Welfare risk assessment: the benefits and common pitfalls." Animal Welfare 21, no. 1 (2012): 73–79. http://dx.doi.org/10.7120/096272812x13345905673764.

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Goldstein, Bernard D. "Risk Assessment/Risk Management Is a Three-Step Process: In Defense of EPA's Risk Assessment Guidelines." Journal of the American College of Toxicology 7, no. 4 (1988): 543–49. http://dx.doi.org/10.3109/10915818809019530.

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The purpose of this article is to focus on the appropriate use and development of risk assessment and to point out that many of the perceived shortcomings, in fact, represent limitations imposed by the framework in which it is being used and failure to understand the situations for which risk assessment is suited. Risk assessment/risk management is really a three-step not a two-step process. The first step, preceding risk assessment, is science policy, in which the guidelines for the generic performance of risk assessments are established. The benefits of risk assessment to appropriate environ

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Kürzinger, Marie-Laure, Ludivine Douarin, Ievgeniia Uzun, et al. "Structured benefit–risk evaluation for medicinal products: review of quantitative benefit–risk assessment findings in the literature." Therapeutic Advances in Drug Safety 11 (January 2020): 204209862097695. http://dx.doi.org/10.1177/2042098620976951.

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A favorable benefit–risk profile remains an essential requirement for marketing authorization of medicinal drugs and devices. Furthermore, prior subjective, implicit and inconsistent ad hoc benefit–risk assessment methods have rightly evolved towards more systematic, explicit or “structured” approaches. Contemporary structured benefit–risk evaluation aims at providing an objective assessment of the benefit–risk profile of medicinal products and a higher transparency for decision making purposes. The use of a descriptive framework should be the preferred starting point for a structured benefit–

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10

Hammond, Tim G., and Jean-Pierre Valentin. "Integrated cardiovascular risk assessment: a balancing act between risk and benefits." Toxicology Letters 221 (August 2013): S23—S24. http://dx.doi.org/10.1016/j.toxlet.2013.06.084.

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11

Matouq, Mohammed. "Process Safety Management Strategies and Risk Assessment." Volume 4 issue 2 4, no. 2 (2021): 52–61. http://dx.doi.org/10.48103/jjeci472021.

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The benefits of achieving excellent process safety prevent or mitigate incidents. Well, the decision-making process has a benefit on risk reduction. This paper guides how an effective system can be established to develop methods and models for mandatory safety and a healthful workplace. The success of health and safety management depends on the discipline, commitment, and participation of all employees to ensure the success of management strategies and ensure the reduction of significant risks. The sustainability challenges are increasingly by evaluating risk and process safety due to the diff

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12

Principe, Peter P. "Ecological benefits assessment: A policy‐oriented alternative to regional ecological risk assessment." Human and Ecological Risk Assessment: An International Journal 1, no. 4 (1995): 423–35. http://dx.doi.org/10.1080/10807039509380027.

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13

Keller, R. P., D. M. Lodge, and D. C. Finnoff. "Risk assessment for invasive species produces net bioeconomic benefits." Proceedings of the National Academy of Sciences 104, no. 1 (2006): 203–7. http://dx.doi.org/10.1073/pnas.0605787104.

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14

Thompson, Ian M., and Donna P. Ankerst. "The Benefits of Risk Assessment Tools for Prostate Cancer." European Urology 61, no. 4 (2012): 662–63. http://dx.doi.org/10.1016/j.eururo.2011.12.012.

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15

Shoupe, Donna. "Individualizing Hormone Therapy to Minimize Risk: Accurate Assessment of Risks and Benefits." Women's Health 7, no. 4 (2011): 475–85. http://dx.doi.org/10.2217/whe.11.42.

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16

Freedman, Andrew N., Binbing Yu, Mitchell H. Gail, et al. "Benefit/Risk Assessment for Breast Cancer Chemoprevention With Raloxifene or Tamoxifen for Women Age 50 Years or Older." Journal of Clinical Oncology 29, no. 17 (2011): 2327–33. http://dx.doi.org/10.1200/jco.2010.33.0258.

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Purpose The Study of Tamoxifen and Raloxifene (STAR) demonstrated that raloxifene was as effective as tamoxifen in reducing the risk of invasive breast cancer (IBC) in postmenopausal women and had lower risks of thromboembolic events, endometrial cancer, and cataracts but had a nonstatistically significant higher risk of noninvasive breast cancer. There is a need to summarize the risks and benefits of these agents. Patients and Methods Baseline incidence rates of IBC and other health outcomes, absent raloxifene and tamoxifen, were estimated from breast cancer chemoprevention trials; the Survei

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Mueller, Natalie, David Rojas-Rueda, Tom Cole-Hunter, et al. "Health impact assessment of active transportation: A systematic review." Preventive Medicine 76 (March 1, 2015): 103–14. https://doi.org/10.1016/j.ypmed.2015.04.010.

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Abstract Objective Walking and cycling for transportation (i.e. active transportation, AT), provide substantial health benefits from increased physical activity (PA). However, risks of injury from exposure to motorized traffic and their emissions (i.e. air pollution) exist. The objective was to systematically review studies conducting health impact assessment (HIA) of a mode shift to AT on grounds of associated health benefits and risks. Methods Systematic database searches of MEDLINE, Web of Science and Transportation Research International Documentation were performed by two independent rese

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Maksymiv, Ivan. "Pesticides: Benefits and Hazards." Journal of Vasyl Stefanyk Precarpathian National University 2, no. 1 (2015): 70–76. http://dx.doi.org/10.15330/jpnu.2.1.70-76.

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Pesticides are an integral part of modern life used to prevent growth of unwanted livingorganisms. Despite the fact that scientific statements coming from many toxicological worksprovide indication on the low risk of the pesticides and their residues, the community especiallylast years is deeply concerned about massive application of pesticides in diverse fields. Thereforeevaluation of hazard risks particularly in long term perspective is very important. In the fact thereare at least two clearly different approaches for evaluation of pesticide using: the first one isdefined as an objective or

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Mousavi, M., I. Ghazi, and B. Omaraee. "Risk Assessment in the Maritime Industry." Engineering, Technology & Applied Science Research 7, no. 1 (2017): 1377–81. http://dx.doi.org/10.48084/etasr.836.

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Risk assessment is a well-developed field which many operators are currently applying to improve their operations and reduce their risk exposure. This paper is intended to provide an overview of the risk assessment for mariners in the Maritime transportation. The risks addressed are primarily those affecting the safety of a vessel, facility or operation. The concept of risk is defined, and the methods available to assess the risks associated with an operation are described. Regulatory requirements that have prompted the development of modern risk assessment practices are described, and future

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Mousavi, M., I. Ghazi, and B. Omaraee. "Risk Assessment in the Maritime Industry." Engineering, Technology & Applied Science Research 7, no. 1 (2017): 1377–81. https://doi.org/10.5281/zenodo.291442.

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Risk assessment is a well-developed field which many operators are currently applying to improve their operations and reduce their risk exposure. This paper is intended to provide an overview of the risk assessment for mariners in the Maritime transportation. The risks addressed are primarily those affecting the safety of a vessel, facility or operation. The concept of risk is defined, and the methods available to assess the risks associated with an operation are described. Regulatory requirements that have prompted the development of modern risk assessment practices are described, and future

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21

Isaev, Eugeni, Dmitry Pervukhin, Georgy Rytikov, Ekaterina Filyugina, and Diana Hayrapetyan. "Risk-based efficiency assessment of information systems." Business Informatics 15, no. 1 (2021): 19–29. http://dx.doi.org/10.17323/2587-814x.2021.1.19.29.

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The implementation of information systems is aimed at improving the financial performance of a company, creating a transparent reporting system and improving many other competitive factors. However, the acquisition of these benefits does not negate the complexity of making a decision whether or not to implement a particular IT project. The total cost of ownership of the information system throughout the life cycle is usually not considered in comparison with the expected benefits from the use of the system, due to the uncertainty of such benefits. Comparative certainty of approaches and method

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22

O'Brien, Mary H. "Ecological alternatives assessment rather than ecological risk assessment: Considering options, benefits, and hazards." Human and Ecological Risk Assessment: An International Journal 1, no. 4 (1995): 357–66. http://dx.doi.org/10.1080/10807039509380020.

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23

Mathes, Karin, and Gerd Winter. "Ecological risk assessment and the regulation of chemicals: III. Balancing risks and benefits." Science of The Total Environment 134 (January 1993): 1679–87. http://dx.doi.org/10.1016/s0048-9697(05)80169-x.

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24

Calabrese, Edward J., and Gary Marchant. "Recognizing and Incorporating Health Benefits of Pollutants in Risk Assessment." Human and Ecological Risk Assessment: An International Journal 7, no. 4 (2001): 639–40. http://dx.doi.org/10.1080/20018091094538.

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25

Szmukler, George. "Risk assessment: ‘numbers' and ‘values’." Psychiatric Bulletin 27, no. 06 (2003): 205–7. http://dx.doi.org/10.1017/s0955603600002257.

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Risk assessment has two components, which I shall term ‘numbers' and ‘values'. ‘Numbers' refer to the estimation of the likelihood that an adverse event will occur in a stated period of time. The methods are mathematical and statistical. ‘Values' refer to the processes of attaching a value to the risk and deciding what should be done about it. Benefits are weighed against costs in what is largely a moral enterprise. Maden (2003, this issue) asks ‘why all the fuss?’ about standardised risk assessment. My fuss is largely about the ‘values', not so much about the ‘numbers'.

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Szmukler, George. "Risk assessment: ‘numbers' and ‘values’." Psychiatric Bulletin 27, no. 6 (2003): 205–7. http://dx.doi.org/10.1192/pb.27.6.205.

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Risk assessment has two components, which I shall term ‘numbers' and ‘values'. ‘Numbers' refer to the estimation of the likelihood that an adverse event will occur in a stated period of time. The methods are mathematical and statistical. ‘Values' refer to the processes of attaching a value to the risk and deciding what should be done about it. Benefits are weighed against costs in what is largely a moral enterprise. Maden (2003, this issue) asks ‘why all the fuss?’ about standardised risk assessment. My fuss is largely about the ‘values', not so much about the ‘numbers'.

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27

Heinonen, Hanna, Alisa Burova, Sanni Siltanen, Jussi Lähteenmäki, Jaakko Hakulinen, and Markku Turunen. "Evaluating the Benefits of Collaborative VR Review for Maintenance Documentation and Risk Assessment." Applied Sciences 12, no. 14 (2022): 7155. http://dx.doi.org/10.3390/app12147155.

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Technical documentation creation is a collaborative process involving several departments in R&D. Even though virtual reality (VR) has been demonstrated to facilitate industrial collaboration and advance the product development lifecycle in earlier studies, it has not been utilized for technical documentation review and risk assessment processes in industrial companies. This article presents a case study where the benefits of VR to maintenance documentation reviews and risk assessments were studied. The virtual reality environment was tested by nine domain experts from an industrial compan

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HANSSON, SVEN OVE. "ECONOMIC (IR)RATIONALITY IN RISK ANALYSIS." Economics and Philosophy 22, no. 2 (2006): 231–41. http://dx.doi.org/10.1017/s0266267106000885.

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Mainstream risk analysis deviates in at least two important respects from the rationality ideal of mainstream economics. First, expected utility maximization is not applied in a consistent way. It is applied to endodoxastic uncertainty, i.e. the uncertainty (or risk) expressed in a risk assessment, but in many cases not to metadoxastic uncertainty, i.e. uncertainty about which of several competing assessments is correct. Instead, a common approach to metadoxastic uncertainty is to only take the most plausible assessment into account. This will typically lead to risk-prone deviations from risk-

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Saint-Hilary, Gaelle, Veronique Robert, Mauro Gasparini, Thomas Jaki, and Pavel Mozgunov. "A novel measure of drug benefit–risk assessment based on Scale Loss Score." Statistical Methods in Medical Research 28, no. 9 (2018): 2738–53. http://dx.doi.org/10.1177/0962280218786526.

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Quantitative methods have been proposed to assess and compare the benefit-risk balance of treatments. Among them, multicriteria decision analysis (MCDA) is a popular decision tool as it permits to summarise the benefits and the risks of a drug in a single utility score, accounting for the preferences of the decision-makers. However, the utility score is often derived using a linear model which might lead to counter-intuitive conclusions; for example, drugs with no benefit or extreme risk could be recommended. Moreover, it assumes that the relative importance of benefits against risks is consta

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Carroll, Andrew. "Risk Assessment and Management in Practice: The Forensicare Risk Assessment and Management Exercise." Australasian Psychiatry 16, no. 6 (2008): 412–17. http://dx.doi.org/10.1080/10398560802068942.

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Objective: There is an emerging consensus that the assessment and management of adverse outcomes in mental health, such as violence and self harm, is best achieved by approaches which incorporate validated tools using “structured professional judgement”. Although several useful tools have emerged from the literature, there is no clear consensus on the best way to integrate these with clinical practice. This paper describes a framework, the Forensicare Risk Assessment and Management Exercise (F.R.A.M.E.), employed by a statewide community forensic mental health service, which incorporates two s

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Stevenson, Megan T., and Jennifer L. Doleac. "Algorithmic Risk Assessment in the Hands of Humans." American Economic Journal: Economic Policy 16, no. 4 (2024): 382–414. http://dx.doi.org/10.1257/pol.20220620.

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We evaluate the impacts of adopting algorithmic risk assessments in sentencing. We find that judges changed sentencing practices in response to the risk assessment, but that discretion played a large role in mediating its impact. Judges deviated from the recommendations associated with the algorithm in systematic ways, suggestive of alternative objectives. As a result, risk assessment did not lead to detectable gains in terms of public safety or reduced incarceration rates. Using simulations, we show that strict adherence to the sentencing recommendations associated with the algorithm would ha

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Rajczi, Alex. "Making Risk-Benefit Assessments of Medical Research Protocols." Journal of Law, Medicine & Ethics 32, no. 2 (2004): 338–48. http://dx.doi.org/10.1111/j.1748-720x.2004.tb00480.x.

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Most medical experiments are reviewed by groups known as Institutional Review Boards (IRBs); according to every standard account of medical research ethics, an IRB should not approve an experiment unless it has an acceptable combination of risks and benefits. This requirement is often stated in different terms. Some codes say that an experiments benefits to individuals and society must outweigh its risks. Others say that the experiment must have a favorable risk-benefit ratio. The Code of Federal Regulations says that risks must be reasonable in relation to the expected benefits.However, even

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Kaul, Sanjay, Norman Stockbridge, and Javed Butler. "Benefit–Risk Tradeoffs in Assessment of New Drugs and Devices." Circulation 142, no. 20 (2020): 1974–88. http://dx.doi.org/10.1161/circulationaha.120.048933.

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Balancing benefits and risks is a complex task that poses a major challenge, both to the approval of new medicines and devices by regulatory authorities and in therapeutic decision-making in practice. Several analysis methods and visualization tools have been developed to help evaluate and communicate whether the benefit–risk profile is favorable or unfavorable. In this White Paper, we describe approaches to benefit–risk assessment using qualitative approaches such as the Benefit Risk Action Team framework developed by the Pharmaceutical Research and Manufacturers of America, and the Benefit–R

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Krebs, John R. "Risk, uncertainty and regulation." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 369, no. 1956 (2011): 4842–52. http://dx.doi.org/10.1098/rsta.2011.0174.

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This paper reviews the relationship between scientific evidence, uncertainty, risk and regulation. Risk has many different meanings. Furthermore, if risk is defined as the likelihood of an event happening multiplied by its impact, subjective perceptions of risk often diverge from the objective assessment. Scientific evidence may be ambiguous. Scientific experts are called upon to assess risks, but there is often uncertainty in their assessment, or disagreement about the magnitude of the risk. The translation of risk assessments into policy is a political judgement that includes consideration o

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Sun, Yihang, Enze Jiang, and Jiahao Wang. "Exploration of Property Insurance Benefits in Extreme Weather." Highlights in Business, Economics and Management 41 (October 15, 2024): 632–39. http://dx.doi.org/10.54097/hmdpbk36.

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In recent years, the increasing frequency of extreme weather events has highlighted the insurance industry's dilemma - the profitability of insurance companies and the capacity of policyholders to bear the burden are in crisis. Therefore, seeking the development of property insurance in this environment is crucial. This paper establishes a Risk Assessment Model with a four-level index system, including four main indicators: natural, economic, social, and engineering defense, to assess the disaster risk and losses of a specific area. Subsequently, a Rate-Adjusted Break-Even Analysis Model is es

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Turki, Sadok, Christophe Sauvey, Sofiene Dellagi, and Nidhal Rezg. "Optimal Decisions and Risk Assessment in Sustainable Supply Chains." Sustainability 13, no. 21 (2021): 12198. http://dx.doi.org/10.3390/su132112198.

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Ye, Xiaofei, Xinliu Sui, Jin Xie, Tao Wang, Xingchen Yan, and Jun Chen. "Assessment of the Economic and Social Impact of Shared Parking in Residential Areas." Information 11, no. 9 (2020): 411. http://dx.doi.org/10.3390/info11090411.

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Shared parking schemes are not commonly implemented in residential areas due to the uncertainty and conflicts associated with the benefits of such schemes for stakeholders, namely, parking suppliers, parking managers, and the public. To evaluate the economic and social impacts of shared parking in residential areas on its stakeholders, the risk and benefit factors were determined through influential analysis and a questionnaire. A risk–benefit model was established to quantify the risks and benefits for stakeholders. The social return on investment and sensitivity analysis were applied to esti

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Chlebowski, Rowan T., Nananda Col, Eric P. Winer, et al. "American Society of Clinical Oncology Technology Assessment of Pharmacologic Interventions for Breast Cancer Risk Reduction Including Tamoxifen, Raloxifene, and Aromatase Inhibition." Journal of Clinical Oncology 20, no. 15 (2002): 3328–43. http://dx.doi.org/10.1200/jco.2002.06.029.

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OBJECTIVE: To update an evidence-based technology assessment of chemoprevention strategies for breast cancer risk reduction. POTENTIAL INTERVENTIONS: Tamoxifen, raloxifene, aromatase inhibition, and fenretinide. OUTCOMES: Outcomes of interest include breast cancer incidence, breast cancer–specific survival, overall survival, and net health benefit. EVIDENCE: A comprehensive, formal literature review was conducted for relevant topics. Testimony was collected from invited experts and interested parties. The American Society of Clinical Oncology (ASCO) prescribed technology assessment procedure w

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Lim, Hui Yin, Harshal Nandurkar, and Prahlad Ho. "Direct Oral Anticoagulants and the Paradigm Shift in the Management of Venous Thromboembolism." Seminars in Thrombosis and Hemostasis 44, no. 03 (2018): 261–66. http://dx.doi.org/10.1055/s-0038-1637750.

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AbstractThe advent of direct oral anticoagulants (DOACs) has revolutionized anticoagulation management in both stroke prevention and venous thromboembolism (VTE) treatment/prevention. Clinical trials and secondary real-world data have shown that DOACs have similar efficacy and, in some cases, improved bleeding safety profiles compared with vitamin K antagonists. Together with benefits of patient convenience, this has shifted the risk–benefit ratio toward long-term anticoagulation. However, current VTE risk assessment models are based on vitamin K antagonists and do not take into account the ne

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Alcorn, Nicola, Sarah Saunders, and Rajan Madhok. "Benefit-Risk Assessment of Leflunomide." Drug Safety 32, no. 12 (2009): 1123–34. http://dx.doi.org/10.2165/11316650-000000000-00000.

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Crentsil, Victor, Jung Lee, and Andre Jackson. "Quantitative Drug Benefit-Risk Assessment." Annals of Pharmacotherapy 48, no. 3 (2014): 306–13. http://dx.doi.org/10.1177/1060028013514376.

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Webb, S., R. Taalman, R. Becker, K. Onuma, and Koichi Igarashi. "Risk perception: A chemical industry view of endocrine disruption in wildlife." Pure and Applied Chemistry 75, no. 11-12 (2003): 2575–91. http://dx.doi.org/10.1351/pac200375112575.

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Manufactured chemicals are essential to the vast array of goods and services that contribute to modern life. Their benefits are innumerable, and society is entirely dependent upon them. At the same time, there is an increasing awareness of the concept of environmental impacts. The challenge is to achieve the appropriate balance between the benefits and risks from chemicals, so that we all may enjoy the benefits of chemicals without significant detriment to current and future human and wildlife health. Ecological risk assessment is the mechanism that allows potential environmental chemical expo

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&NA;. "In large study, benefits outweigh suicide risk." Nursing 37, no. 6 (2007): 18. http://dx.doi.org/10.1097/01.nurse.0000271794.09390.a5.

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Raffaele, Kathleen C. "Benefits and Barriers to Using Epidemiology Data in Environmental Risk Assessment." Open Epidemiology Journal 4, no. 1 (2011): 99–105. http://dx.doi.org/10.2174/1874297101104010099.

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Grover, Steven A., and Ilka Lowensteyn. "The Challenges and Benefits of Cardiovascular Risk Assessment in Clinical Practice." Canadian Journal of Cardiology 27, no. 4 (2011): 481–87. http://dx.doi.org/10.1016/j.cjca.2011.04.008.

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Hudig, Dirk. "The Problem of Low and Uncertain Risks: Balancing Risks and Benefits." European Journal of Risk Regulation 3, no. 2 (2012): 157–60. http://dx.doi.org/10.1017/s1867299x00001999.

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Both the Lisbon Treaty and the new Inter-Institutional Agreement strengthen the role of the European Parliament (EP) as co-legislator. At the same time, European Union (EU) officials increasingly recognise the need for broader acceptance of the principles and agreements of the Better (Smart) Regulation strategy, as proposed in an October 2010 Commission Communication. There is a need to make high quality risk management decisions in a more risk averse environment and a changed policy framework. Indeed, principles supporting better regulation have become more widely adopted by all EU institutio

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Goossens, L. H. J., and C. C. Glansdorp. "Operational Benefits and Risk Reduction of Marine Accidents." Journal of Navigation 51, no. 3 (1998): 368–81. http://dx.doi.org/10.1017/s037346339800798x.

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Safety is a crucial issue in densely sailed waterways. Traffic guidance systems (VTS) have proven to be valuable in this respect. The effectiveness of current systems and the benefits for improvements in navigation are addressed in this paper. Relevant incidents are analysed with a risk assessment tool (Accident Sequence Precursor method) developed for complex system analyses. The method is capable of drawing conclusions on a high level: strategic and tactic events and the human errors associated with the navigator's task cycle. Changes in current VTS systems will not likely improve safety rec

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Levitan, Bennett, Zhong Yuan, Alexander GG Turpie, et al. "Quantitative Benefit–Risk Assessment of Rivaroxaban for the Prevention of Venous Thromboembolism." Blood 114, no. 22 (2009): 169. http://dx.doi.org/10.1182/blood.v114.22.169.169.

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Abstract Abstract 169 Introduction: Venous thromboembolism (VTE) is a common complication after hip or knee replacement and is associated with significant morbidity and mortality. Anticoagulants reduce the risk of these complications, but can also result in increased bleeding, thus requiring an assessment of benefit–risk. Patients and Methods: To obtain more precise estimates of treatment effects on low frequency events, data were pooled from 4 phase 3 randomized clinical trials (RECORD1–4) of rivaroxaban vs enoxaparin regimens (or enoxaparin/placebo combination in 1 study) for the prevention

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Ganapathy, Venkatasubramanian. "AI-Based Risk Assessments in Forensic Auditing: Benefits, Challenges and Future Implications." Shodh Sari-An International Multidisciplinary Journal 03, no. 04 (2024): 100–128. http://dx.doi.org/10.59231/sari7750.

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Forensic auditing is a critical component of ensuring financial integrity and detecting fraud within organizations. Traditional methods of risk assessment in forensic auditing often rely on manual processes, which can be time-consuming, labour-intensive, and prone to human error. In recent years, the integration of artificial intelligence (AI) techniques has revolutionized the field, offering more efficient and accurate risk assessment capabilities. This abstract explores the role of AI-based risk assessment in forensic auditing, highlighting its benefits, challenges, and future implications.

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Kovaleva, Maria Yuryevna, and Vlada Konstantinovna Fediaeva. "The Assessment of Potential Benefit and Risk Balance in the Process of Clinical Practice Guidelines Development and Grading the Evidence." Medical Technologies. Assessment and Choice (Медицинские технологии. Оценка и выбор), no. 4 (38) (December 1, 2019): 8–17. http://dx.doi.org/10.31556/2219-0678.2019.38.4.008-017.

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Aim of the study. A review of international practice of “benefit-risk” ratio assessment in the process of clinical practice guidelines (CPG) development; assessment of its acceptability for Russian Federation. Material and methods. We analyzed official methodological guides of the GRADE working group and information from the websites of the professional associations, indicated on the official GRADE website. Additionally, the review of methods of quantitative assessment of risk-benefit ratio was conducted. The search was performed in Pubmed and Embase in April 2019, according to the queries “be

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