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Journal articles on the topic 'Benign gallbladder disease'

Author: Grafiati

Published: 7 June 2025

Last updated: 16 July 2025

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1

Du, Yanzhang, Wennie A. Wijaya, and Wei Hui Liu. "Advancements in metabolomics research in benign gallbladder diseases: A review." Medicine 103, no. 21 (2024): e38126. http://dx.doi.org/10.1097/md.0000000000038126.

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The burgeoning field of metabolomics has piqued the interest of researchers in the context of benign gallbladder diseases, which include conditions such as gallbladder polyps, gallstones, and cholecystitis, which are common digestive system disorders. As metabolomics continues to advance, researchers have increasingly focused their attention on its applicability in the study of benign gallbladder diseases to provide new perspectives for diagnostic, therapeutic, and prognostic evaluation. This comprehensive review primarily describes the techniques of liquid chromatography-mass spectrometry, ga

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John, Susan, Terence Moyana, Wael Shabana, Cindy Walsh, and Matthew D. F. McInnes. "Gallbladder Cancer: Imaging Appearance and Pitfalls in Diagnosis." Canadian Association of Radiologists Journal 71, no. 4 (2020): 448–58. http://dx.doi.org/10.1177/0846537120923273.

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Gallbladder cancer is an uncommon malignancy with an overall poor prognosis. The clinical and imaging presentation of gallbladder cancer often overlaps with benign disease, making diagnosis difficult. Gallbladder cancer is most easily diagnosed on imaging when it presents as a mass replacing the gallbladder. At this stage, the prognosis is usually poor. Recognizing the features of gallbladder cancer early in the disease can enable complete resection and improve prognosis. Recognition of the patterns of wall enhancement on computed tomography can help differentiate gallbladder cancer from benig

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Mencarini, Lara, Amanda Vestito, Rocco Maurizio Zagari, and Marco Montagnani. "New Developments in the Ultrasonography Diagnosis of Gallbladder Diseases." Gastroenterology Insights 15, no. 1 (2024): 42–68. http://dx.doi.org/10.3390/gastroent15010004.

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Gallbladder diseases are very common, and their diagnosis is based on clinical–laboratory evaluation and imaging techniques. Considering the different imaging diagnostic tools, ultrasound (US) has the advantage of high accuracy combined with easy availability. Therefore, when a gallbladder disease is suspected, US can readily assist the clinician in the medical office or the emergency department. The high performance of US in the diagnosis of gallbladder diseases is mainly related to its anatomic location. The most frequent gallbladder pathological condition is gallstones disease, easily diagn

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Gore, Richard M., Vahid Yaghmai, Geraldine M. Newmark, Jonathan W. Berlin, and Frank H. Miller. "Imaging benign and malignant disease of the gallbladder." Radiologic Clinics of North America 40, no. 6 (2002): 1307–23. http://dx.doi.org/10.1016/s0033-8389(02)00042-8.

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5

Vessey, Martin, and Rosemary Painter. "Oral contraceptive use and benign gallbladder disease; revisited." Contraception 50, no. 2 (1994): 167–73. http://dx.doi.org/10.1016/0010-7824(94)90052-3.

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6

Chung, Hwe Hoon, Ji Eun Kim, Kwang Hyun Chung, and Joo Kyung Park. "Comparison between early gall bladder cancer and advanced gall bladder cancer in terms of clinicopathologic factors: large volume tertiary center experience." International Journal of Advances in Medicine 9, no. 3 (2022): 201. http://dx.doi.org/10.18203/2349-3933.ijam20220359.

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Background: Early diagnosis of gallbladder cancer (GBC) which enables to surgical resection is key for improve prognosis. Aim of this study was to investigate clinical features of early GBC patients compare to advanced ones.Methods: We retrospectively reviewed medical records of all pathologically confirmed primary GBC patients between in single tertiary referral center.Results: 250 patients (57.3%) were early GBC (stage I and II) and 186 (42.7%) were advanced GBC (stage III and IV). Less patients with early GBC had symptom at initial diagnosis (69.2% versus 90.8%, p<0.001). Large number of

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Fosio, Margherita, Giulia Cherobin, Roberto Stramare, Matteo Fassan, and Chiara Giraudo. "Coronary Artery Disease and Gallbladder Inflammatory Pseudopolyps." Diagnostics 12, no. 1 (2022): 155. http://dx.doi.org/10.3390/diagnostics12010155.

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Axial MR image demonstrating multiple small gallbladder polypoid lesions characterized by contrast enhancement in a 78-year-old male hospitalized for acute chest pain due to coronary artery disease who showed fever and emesis during hospitalization and had signs of acute acalculous cholecystitis at computed tomography. Given the overall clinical conditions and the MR features, the inflammatory origin of the polyps was considered. The patient underwent cholecystectomy and the histological diagnosis of gallbladder inflammatory pseudopolyps was confirmed. This rare entity represents 5–10% of all

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8

Baba, Hiroyuki, Mai Wakabayashi, Atsushi Oba, et al. "Primary Papillary Hyperplasia of the Gallbladder Mimicking Gallbladder Cancer." International Surgery 99, no. 3 (2014): 247–51. http://dx.doi.org/10.9738/intsurg-d-13-00252.1.

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Abstract Primary papillary hyperplasia of the gallbladder (PPHG) is a rare entity. PPHG is a benign diffuse mucosal projection without any background chronic inflammation-related disease of the gallbladder or bile ducts. Reported cases of PPHG are limited in that its characteristics are not well defined. We herein report a case of PPHG mimicking gallbladder cancer in radiologic investigations and present a review of the literature. Also coincident erythroderma is discussed.

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Koshenkov, Vadim P., Tulay Koru-Sengul, Dido Franceschi, Peter J. DiPasco, and Steven E. Rodgers. "Predictors of incidental gallbladder cancer in patients undergoing cholecystectomy for benign gallbladder disease." Journal of Surgical Oncology 107, no. 2 (2012): 118–23. http://dx.doi.org/10.1002/jso.23239.

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10

Hines, J. "Predictors of Incidental Gallbladder Cancer in Patients Undergoing Cholecystectomy for Benign Gallbladder Disease." Yearbook of Surgery 2014 (2014): 242–43. https://doi.org/10.1016/j.ysur.2013.11.002.

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11

Ratan, Md Ezharul Haque, Hasina Alam, and Md Abdul Karim. "Can All Benign Gallbladder Diseases be Managed Laparoscopically?" BIRDEM Medical Journal 8, no. 1 (2017): 35–41. http://dx.doi.org/10.3329/birdem.v8i1.35037.

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Background: Laparoscopic cholecystectomy (LC) operation is widely practiced in gallbladder diseases. However, controversy persists for LC in acute gall bladder disease, as risk of complications appears to be greater than open procedure1. This study presents the outcome of LCs performed as the first option of treatment in benign chronic as well as acute gall bladder diseases.Methods: Twelve hundred consecutive patients of gall bladder disease, both acute and chronic, underwent cholecystectomies by a single surgeon using standard four port technique. Age, sex, diabetes, prior abdominal procedure

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Elsayes, K. M., E. P. Oliveira, V. R. Narra, F. M. EL-Merhi, and J. J. Brown. "Magnetic resonance imaging of the gallbladder: spectrum of abnormalities." Acta Radiologica 48, no. 5 (2007): 476–82. http://dx.doi.org/10.1080/02841850701324102.

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Various pathologies involving the gallbladder can manifest clinically, producing nonspecific clinical symptoms and making diagnosis difficult and challenging. Real-time sonography is the most widely used diagnostic study for the gallbladder and the primary screening examination of choice. With increasing use of magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP), gallbladder pathology is frequently seen. Understanding the basic patterns of various disease manifestations and appearance on MRI is the key to making an accurate diagnosis. Given its inherent tissue contrast and

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13

Kawahara, Soichiro, Takeshi Tomoda, Hironari Kato, et al. "Accuracy of Endoscopic Transpapillary Gallbladder Drainage with Liquid-Based Cytology for Gallbladder Disease." Digestion 103, no. 2 (2021): 116–25. http://dx.doi.org/10.1159/000519250.

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<b><i>Introduction:</i></b> Gallbladder carcinoma is often difficult to distinguish from benign gallbladder diseases. While the diagnostic accuracy of endoscopic transpapillary gallbladder drainage (ETGD) has been reported, these results were obtained retrospectively. This prospective study aimed to evaluate the cytological diagnostic accuracy of ETGD in patients with gallbladder disease. <b><i>Methods:</i></b> This single-arm prospective clinical trial included a total of 35 patients scheduled to undergo ETGD between March 2017 and September 201

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Dvoryakovsky, Igor V., S. A. Ivleva, and I. E. Smirnov. "ULTRASONIC DIAGNOSIS OF GALLBLADDER POLYPOSIS IN CHILDREN." Russian Pediatric Journal 21, no. 4 (2019): 225–29. http://dx.doi.org/10.18821/1560-9561-2018-21-4-225-229.

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An overview of the data on the features of ultrasound in polyposis of the gallbladder is presented. The polyposis of the gallbladder especially in children is the rare disease requiring careful attention since the transition from the benign mass into carcinoma is not impossible. The extensive use of ultrasound diagnostics has significantly improved the detection of gallbladder polyposis. In the review of literature data and own research, the possibilities of the visualization of various forms of gallbladder polyposis in children are considered, and a scheme for the dynamic control of polyp mor

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Poddar, Elisha, Prakash Mainali, Suraj Shrestha, et al. "Xanthogranulomatous Cholecystitis Mimicking Carcinoma Gallbladder." Case Reports in Hepatology 2023 (February 13, 2023): 1–5. http://dx.doi.org/10.1155/2023/2507130.

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Xanthogranulomatous cholecystitis (XGC) is a rare benign chronic inflammatory disease of the gallbladder that often presents as cholecystitis and can mimic gallbladder carcinoma. Distinguishing XGC from gallbladder cancer preoperatively is challenging. We present a case of a 62-year-old male who presented with features of carcinoma gallbladder in the CECT abdomen and MRCP. Intraoperatively, there was a mass in the gallbladder and extension into the adjacent structures with involvement of the hepatic artery, 1st part of the duodenum, portal vein, and hepatic flexure of the colon, and thus a pal

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Proctor, Dominic W., Richard Goodall, Kim Borsky, et al. "Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019." Annals of Surgery Open 5, no. 2 (2024): e453. http://dx.doi.org/10.1097/as9.0000000000000453.

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Objective: The aim of this observational study was to analyze trends in the incidence, mortality, and disability-adjusted life years (DALYs) of benign gallbladder and biliary diseases across high-income countries between 1990 and 2019. Background: Benign gallbladder and biliary diseases place a substantial burden on healthcare systems in high-income countries. Accurate characterization of the disease burden may help optimize healthcare policy and resource distribution. Materials and methods: Age-standardized incidence rates (ASIRs), age-standardized mortality rates (ASMRs), and DALYs data for

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Nicol, Alice V., Jessica Y. S. N., and Rachel Colbran. "Pure squamous cell carcinoma of the gallbladder in a patient with perforated calculus cholecystitis." International Surgery Journal 9, no. 2 (2022): 476. http://dx.doi.org/10.18203/2349-2902.isj20220345.

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Gallbladder carcinoma is one of the most common and aggressive malignancies to arise from the biliary tract. However, pure squamous cell carcinoma (SCC) originating from the gallbladder is exceptionally rare, reported to represent less than 1% of all malignancies. An 89-year-old Australian male presented with symptoms and imaging consistent with acute calculus cholecystitis. After failed conservative management he underwent a subtotal cholecystectomy. Diagnosis on histopathological examination demonstrated SCC of the gallbladder. This case highlights the importance of considering gallbladder m

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18

Khan, Shujaat, Mohammad Azhar Rashikh, and Nemer Alotaibi. "Role of Detailed Intraoperative Macroscopic Examination of Cholecystectomy Specimens for Deciding Specimens Needing Histological Evaluation for Diagnosing Incidental Carcinoma of Gallbladder at the Earliest? A Systematic Review." International Journal of Research and Review 9, no. 10 (2022): 257–70. http://dx.doi.org/10.52403/ijrr.20221030.

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Background: Several studies recommending selective or routine histopathological examination of gallbladder specimens have been done. However, the argument between these studies is based on intraoperative suspicion of IGBC (incidental gallbladder carcinoma) for deciding on specimen sending. This study aims to know whether a detailed intraoperative examination of cholecystectomy specimens is required for deciding on specimens needing histological evaluation and suspecting IGBCs at the earliest. Methodology: The systematic review has been done as per the PRISMA guidelines. Various articles were s

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Hajong, Ranendra, Gareth Lyngwa, Donboklang Lynser, and Pinky Rabha. "Xanthogranulomatous cholecystitis infiltrating anterior abdominal wall: a rare case report." International Surgery Journal 11, no. 12 (2024): 2162–64. http://dx.doi.org/10.18203/2349-2902.isj20243567.

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Xanthogranulomatous cholecystitis (XGC) is a benign chronic inflammatory disease of the gallbladder often presenting as features of chronic cholecystitis. The disease closely mimics gallbladder carcinoma (GBC) and distinguishing XGC from gallbladder cancer preoperatively is very challenging. Biochemical or radiological investigations cannot differentiate XGC from GBC and they share overlapping symptoms. Reporting here is a 31 year old female patient who presented with features of failed attempt of cholecystectomy due to suspected carcinoma gallbladder at an outside hospital. Even CECT abdomen

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Li, Wenya, Feizhao Jiang, Xiaoxiao Li, Hong Li, and Zhihai Zheng. "A rare case of eosinophilic cholangiopathy." International Journal of Immunopathology and Pharmacology 34 (January 2020): 205873842094175. http://dx.doi.org/10.1177/2058738420941752.

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Eosinophilic cholangiopathy is termed as a rare, benign, and self-limiting disease. Moreover, the interference of malignant tumor to diagnosis and the changing process of disease make the accurate treatment proposal challenging. A significant number of patients require surgery for the definitive diagnosis and resolution of symptoms. We put forward a case of eosinophilic cholangiopathy infiltrating the gallbladder and bile duct with bone marrow involved, coupled with peripheral eosinophilia. The patient underwent a successful treatment using laparoscopic cholecystectomy and steroids, instead of

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Lundgren, L., M. Henriksson, B. Andersson, and P. Sandström. "Cost‐effectiveness of gallbladder histopathology after cholecystectomy for benign disease." BJS Open 4, no. 6 (2020): 1125–36. http://dx.doi.org/10.1002/bjs5.50325.

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22

Singla, Vikas, Rachit Agarwal, Shrihari Anil Anikhindi, et al. "Role of EUS-FNA for gallbladder mass lesions with biliary obstruction: a large single-center experience." Endoscopy International Open 07, no. 11 (2019): E1403—E1409. http://dx.doi.org/10.1055/a-0982-2862.

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Abstract Background and study aims Although endoscopic ultrasound (EUS)-guided fine-needle aspiration (EUS-FNA) is an established modality for pathological sampling of pancreatic and biliary lesions, limited data are available on the diagnostic value of EUS-FNA for evaluation of gallbladder mass lesions, a common cause of obstructive jaundice. We aimed to evaluate the usefulness of EUS-FNA for diagnosis of gallbladder mass lesions presenting with biliary obstruction. Patients and methods This study was a retrospective analysis of data from patients who had undergone EUS-FNA for gallbladder mas

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Matsubara, Saburo. "Clinical Advances in the Diagnosis and Treatment of Biliary Tract Diseases." Journal of Clinical Medicine 12, no. 6 (2023): 2282. http://dx.doi.org/10.3390/jcm12062282.

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Although the biliary tract is a small organ, it is diverse in location (intrahepatic bile ducts, extrahepatic bile ducts, gallbladder, and ampulla) and disease (including benign and malignant), thus a multidisciplinary approach involving endoscopists, surgeons, oncologists, radiologists, and infectious disease specialists is often required to treat biliary tract disease [...]

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Sharma, Shambhavi, Sanjay Poudel, Samir Shrestha, Surendra Shah, Shanta Bir Maharjan, and Sajan Shrestha. "Accuracy of macroscopic examination of gall bladder specimens for malignancy after cholecystectomy." Journal of Patan Academy of Health Sciences 11, no. 1 (2024): 10–14. http://dx.doi.org/10.3126/jpahs.v11i1.65644.

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Introduction: Routinely all specimens are sent for HPE due to the possibility of missing incidental gall bladder carcinoma(IGBC) which has a incidence of 0.2-2.9%. Missing IGBC would have a devastating effect on patients. However, many studies have reported thorough macroscopic examination of gallbladder specimen by surgeons would be enough to rule out carcinoma. Those missed carcinomas are at early stage (pT1a) which would not change the management of the patients. Method: It was a prospective observational study that included all patients undergoing cholecystectomy for benign gallstone disea

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Prakash, Gandikota Venkata, Ajay Babu K, Madan Sundar, Purushotham G, Saddi Tejaswi, and Vuribindi Manognitha Reddy. "A Prospective Study on Analysis of Histopathological Variations in Post Cholecystectomy Specimens Done for Benign Conditions in a Tertiary Care Hospital, Tirupati." Journal of Evidence Based Medicine and Healthcare 8, no. 32 (2021): 2956–61. http://dx.doi.org/10.18410/jebmh/2021/540.

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BACKGROUND Cholecystectomy is a common surgical procedure done worldwide for both benign and neoplastic conditions. Cholecystectomy for benign conditions is performed based on clinical signs, symptoms, Ultrasound, CT. Hence there is fair chance of missing early malignant lesions like carcinoma-in-situ and other early carcinomas. Aim: The aim of the study is to analyse histopathological variations in post cholecystectomy specimens done for benign lesions. METHODS The study was conducted in Department of General Surgery, SVRRGGH, Tirupati, for a period of one year, from March 2019 to April 2020.

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Singh, Prachi, Faiyaz Ahmad, Shyamoli Dutta, Seema Awasthi, and V. K. Singh. "Spectrum of Benign Histopathological Lesions in Cholecystectomy Specimens." Asian Journal of Medical Research 9, no. 2 (2020): 8–13. http://dx.doi.org/10.47009/ajmr.2020.9.2.pt2.

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Background: The most commonly received specimen in any histopathology laboratory is cholecystectomy specimen. The majority of the cholecystectomies are done for Cholelithiasis. Inflammation may be acute, chronic or acute on chronic. It almost always occurs in association with gallstones, which is responsible for carcinoma and if the diagnosed early prognosis of the carcinoma gall bladder is good. Histopathological examination is therefore a must for diagnosis of early carcinomas. Subjects and Methods: 100 cholecystectomy specimens from patients of all ages were included. All specimens were sub

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Abdelmoneim, Ahmed Hassan, Adham Darweesh, Avin Kounsal, and Abdelwahed Samir Abougazia. "A case report of Xanthogranulomatous Cholecystitis." Albanian Journal of Trauma and Emergency Surgery 5, no. 1 (2021): 813–18. http://dx.doi.org/10.32391/ajtes.v5i1.166.

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 Xanthogranulomatous cholecystitis is a benign, uncommon type of chronic cholecystitis manifested by focal or diffuse severe inflammatory process of the gallbladder (GB). It is inflammatory disease of the gallbladder characterized by the infiltrations of plasma cells, lipid-laden histiocytes, and the fibroblasts proliferation in GB wall. Gallstones are present in all patients, and like most symptomatic gallbladder diseases, there is a female predominance. It is an active inflammatory process which could leads to significant morbidity. The term Xanthogranulomatous cholecystitis was initia

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Safoyev, Baqodir Barnoyevich Ibodov Ixtiyor Baxtiyorovich. "EFFECTIVENESS MODERN MININVASIVE LAPAROSCOPIC CHOLECYSTECTOMY DURING THE COMPLICATION OF ACUTE CHOLECYSTITIS." ilm-fan 1, no. 25 (2023): 4–5. https://doi.org/10.5281/zenodo.8429716.

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Laparoscopic surgical procedures can today be performed in almost all hospitals and the experiences of surgeons are increasing day by day. Cholecystectomy is especially one of the laparoscopic treatments that many surgical assistants firstly learn and apply. The validity of laparoscopic cholecystectomy (LC) is today indisputable in symptomatic gallbladder stones, other benign gallbladder diseases and early stage malignancy according to certain authors.[1–3] It is already the most common and widely applied laparoscopic intervention today.Acute cholecystitis is an inflammatory disease that

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Neculoiu, Damaris, Lavinia Claudia Neculoiu, Ramona Mihaela Popa, and Rosana Mihaela Manea. "The Many Hidden Faces of Gallbladder Carcinoma on CT and MRI Imaging—From A to Z." Diagnostics 14, no. 5 (2024): 475. http://dx.doi.org/10.3390/diagnostics14050475.

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Gallbladder carcinoma represents the most aggressive biliary tract cancer and the sixth most common gastrointestinal malignancy. The diagnosis is a challenging clinical task due to its clinical presentation, which is often non-specific, mimicking a heterogeneous group of diseases, as well as benign processes such as complicated cholecystitis, xanthogranulomatous cholecystitis, adenomyomatosis, porcelain gallbladder or metastasis to the gallbladder (most frequently derived from melanoma, renal cell carcinoma). Risk factors include gallstones, carcinogen exposure, porcelain gallbladder, typhoid

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Siddiqui, Mohd Adnan, Navneet Dwivedi, Mohammed Haris Siddiqui, et al. "NMR spectroscopy-based analysis of gallstones of cancerous and benign gallbladders from different geographical regions of the Indian subcontinent." PLOS ONE 18, no. 6 (2023): e0286979. http://dx.doi.org/10.1371/journal.pone.0286979.

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Analysis of the chemical composition of gallstones is vital for the etiopathogenesis of gallstone diseases that can ultimately help in the prevention of its formation. In the present study, gallstones from seven different regions of India were analyzed to highlight the major difference in their composition. Also, gallstones of different pathological conditions i.e., benign (chronic cholecystitis, CC) and malignant gallbladder disease (gallbladder cancer GBC) were characterized. The type of polymorphs of cholesterol molecules was also studied to provide insight into the structure of gallstones.

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Zhou, Yuan, and Zhan-Qing Chen. "Research on the prognostic value of adjusting intraperitoneal three-dimensional quality evaluation mode in laparoscopic cholecystectomy patients." World Journal of Gastrointestinal Surgery 16, no. 4 (2024): 1078–86. http://dx.doi.org/10.4240/wjgs.v16.i4.1078.

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BACKGROUND Benign gallbladder diseases have become a high-prevalence condition not only in China but also worldwide. The main types of benign gallbladder diseases include gallbladder polyps, acute and chronic cholecystitis, and gallstones, with gallstones being the most common, accounting for over 70% of cases. Although the mortality rate of benign gallbladder diseases is low, they carry obvious potential risks. Studies have shown that an increased incidence of benign gallbladder diseases can increase the risk of cardiovascular diseases and gallbladder cancer, resulting in a substantial diseas

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De La Ossa, Juan, Natalie Donn, Talar Kachechian, Harry Nguyen, and Karthik Mohan. "S1376 A Case of Benign Gallbladder Disease With Elevated Tumor Markers." American Journal of Gastroenterology 115, no. 1 (2020): S694. http://dx.doi.org/10.14309/01.ajg.0000707552.56362.04.

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Naveed, Shah, Hasina Qari, Asma Altaf, and Mah Para. "A Review of Recent Data in the Treatment of Gallbladder Cancer." Bangladesh Journal of Medical Science 15, no. 3 (2016): 320–25. http://dx.doi.org/10.3329/bjms.v15i3.22484.

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Gallbladder cancer is now considered a distinct clinical entity, allowing for a separate analysis from that of other malignancies of the biliary tree. Symptoms related to a malignant tumor of the gallbladder include jaundice and abdominal pain, or a palpable abdominal mass that occurs in a late stage of the disease. The majority of patients with operable gallbladder cancer are diagnosed by cholecystectomy performed for presumed benign disease, mostly cholelithiasis, a clinical entity known as incidental gallbladder cancer. Given the poor prognosis if tumor invasion beyond the muscular layer an

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Müller, Bettina G., Xabier De Aretxabala, and Manuel González Domingo. "A Review of Recent Data in the Treatment of Gallbladder Cancer: What We Know, What We Do, and What Should Be Done." American Society of Clinical Oncology Educational Book, no. 34 (May 2014): e165-e170. http://dx.doi.org/10.14694/edbook_am.2014.34.e165.

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Gallbladder cancer is now considered a distinct clinical entity, allowing for a separate analysis from that of other malignancies of the biliary tree. Symptoms related to a malignant tumor of the gallbladder include jaundice and abdominal pain, or a palpable abdominal mass that occurs in a late stage of the disease. The majority of patients with operable gallbladder cancer are diagnosed by cholecystectomy performed for presumed benign disease, mostly cholelithiasis, a clinical entity known as incidental gallbladder cancer. Given the poor prognosis if tumor invasion beyond the muscular layer an

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Lalovic, Nenad, Radovan Cvijanovic, Nikolina Dukic-Vladicic, Radmil Maric, Dragana Jokanovic, and Danijela Batinic-Skipina. "Adenomyomatosis of the gallbladder: Case report." Medical review 64, no. 5-6 (2011): 323–26. http://dx.doi.org/10.2298/mpns1106323l.

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Adenomyomatosis of the gallbladder is a benign, mostly asymptomatic condition of an unknown aetiology. Hyperplastic changes in the gallbladder wall cause an overgrowth of the mucosa, thickening of the muscular wall, and formation of intramural diverticula or sinus tracts termed Rokitansky-Aschoff sinuses. Adenomyomatosis is divided on general, segmental and localized. Ultrasound examination, computerized tomography and magnetic resonance are used in diagnostic procedure. The importance of the disease lies in the fact that it can cause recurrent right upper quadrant pain so it must be concerned

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Karim, Syeda Noorjahan, Md Neaz Nowsher, and Shamim Rahman. "Spectrum of Morphologic Changes in Histopathological Specimen of Gallbladder in a Tertiary Care Hospital." Mediscope 9, no. 1 (2022): 1–4. http://dx.doi.org/10.3329/mediscope.v9i1.58519.

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Background: Diseases of gallbladder are incidentally found and when symptomatic, present with sign and symptoms of cholecystitis and cholelithiasis. Routine examination of gallbladder both grossly and microscopically shows many interesting findings. Aim: The aim of the study was to observe and analyze the diverse morphological and histopathological features of gallbladder specimens following cholecystectomy procedure. Methods: This cross-sectional study was carried out at the Department of Pathology, Gazi Medical College, Khulna; from April 2019 to March 2021 and the sample size was 62. After

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Mahmoud, Zrng, Kamal Saeed, and Farman Hassan. "Incidence of Gall Bladder Carcinoma after Cholecystectomy in Patient Attending Shorsh General Teaching Hospital in Sulaimaniyah." Advanced Medical Journal 10, no. 1 (2025): 193–98. https://doi.org/10.56056/amj.2025.335.

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Background and objectives: Gallbladder carcinoma is the most common biliary tract malignancy and the fifth most common cancer of the gastrointestinal tract. An incidental finding of carcinoma is incidental gallbladder carcinoma. This study is aimed to find the incidence of hidden gallbladder carcinoma. Methods: The records of 307 patients who underwent a cholecystectomy over five years (January 2017 to December 2021) were reviewed as a retrospective cohort study at Shorsh General Teaching Hospital, Sulaimaniyah city, Kurdistan region, Iraq. The patient's data were collected using a simple rand

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Alabi, Andrew, A. D. Arvind, Nikhil Pawa, Shakir Karim, and Jason Smith. "Incidental Gallbladder Cancer: Routine versus Selective Histological Examination After Cholecystectomy." Surgery Journal 07, no. 01 (2021): e22-e25. http://dx.doi.org/10.1055/s-0040-1722175.

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Abstract Background Incidental gallbladder cancer is relatively rare, with an incidence ranging between 0.19 and 5.5% of all the cholecystectomies for benign disease, and carries a poor prognosis. Currently, in the literature, there appears to be some controversy about whether all gallbladder specimens should be sent for routine histopathology. The aim of this study was to investigate the need for either routine or selective histopathological evaluation of all gallbladder specimens following cholecystectomy in our institution. Methods The records of all patients who underwent a cholecystectomy

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Nong, Lerato Hector, and Mirza Mohamod Zahir Uddin Bhuiyan. "Analysis of Histology of Post-Cholecystectomy Gallbladder Specimens at Mankweng Hospital." European Journal of Medical and Health Sciences 7, no. 3 (2025): 55–58. https://doi.org/10.24018/ejmed.2025.7.3.2329.

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Background: Gallbladder disease is less common in black South Africans. Most common gallbladder pathologies are benign. The mainstay surgical treatment of gall bladder disease is cholecystectomy, with the laparoscopic approach being the gold standard. All post-cholecystectomy gallbladder specimens (GBS) are sent for histopathology investigation to detect cancer as standard practice at Mankweng Academic Hospital. The main aim of this study is to evaluate the histopathologic pattern of gallbladder specimens in patients who underwent elective or emergency cholecystectomies at Mankweng Hospital fr

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Vedamurthy, Amar, Rajesh Krishnamoorthi, Shayan Irani, and Richard Kozarek. "Endoscopic Management of Benign Pancreaticobiliary Disorders." Journal of Clinical Medicine 14, no. 2 (2025): 494. https://doi.org/10.3390/jcm14020494.

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Endoscopic management of benign pancreaticobiliary disorders encompasses a range of procedures designed to address complications in gallstone disease, choledocholithiasis, and pancreatic disorders. Acute cholecystitis is typically treated with cholecystectomy or percutaneous drainage (PT-GBD), but for high-risk or future surgical candidates, alternative decompression methods, such as endoscopic transpapillary gallbladder drainage (ETP-GBD), and endoscopic ultrasound (EUS)-guided gallbladder drainage (EUS-GBD), are effective. PT-GBD is associated with significant discomfort as well as variable

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Sourabh, Sharma, Kumar Vikesh, Sharma Swati, Thakkar Konark, Gupta Kavita, and Gheewala Panth. "Lesion Mimicking Malignancy: A Case Series." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 2093–99. https://doi.org/10.5281/zenodo.12608019.

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<strong>Background:</strong>  Treatment of malignancy requires preoperative confirmation in most of the cases, to provide a definitive treatment. However, in some cases it’s not possible to positively ascertain the diagnosis preoperatively and these patients are treated as malignancy. A few of them turns out to be benign lesion on histopathological examination despite of malignancy like radiological/ intra operative finding. So, benign diseases should also be kept in the differential diagnosis for doubtful cases. <strong>Method:</strong> In this case series we are reportin

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Drakonaki, Elena, Stamatios Kokkinakis, Ioannis Karageorgiou, Neofytos Maliotis, Anna Ioannidoy, and Emmanouil K. Symvoulakis. "A case of incidental infantile gallbladder adenomyomatosis: an unusual US finding of uncertain clinical significance." Journal of Ultrasonography 20, no. 83 (2020): 318–21. http://dx.doi.org/10.15557/jou.2020.0055.

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Adenomyomatosis of the gallbladder is defined as hypertrophy of the gallbladder mucosal epithelium that invaginates into a thickened muscularis propria, leading to the formation of intramural diverticula. It is typically considered a benign condition most commonly affecting adults and, rarely, children. In this case report, we present a case of gallbladder adenomyomatosis in a 3-month-old infant. The diagnosis was made incidentally on ultrasound examination of the abdomen, in an otherwise asymptomatic child with no laboratory test abnormalities and no underlying disease. The purpose of this ca

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Raza, A. K. M. Maruf, Sardar Md Rezaul Islam, Tasnim Ishrat, Nabir Hossain, Shah Alam Sarkar, and Sardar Saminul Islam. "Histopathological Disease Spectrum of Cholecystectomy Specimen: A Retrospective Observational Study." Journal of Ad-din Women's Medical College 11, no. 1 (2023): 22–25. http://dx.doi.org/10.3329/jawmc.v11i1.70462.

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Background: Gallstone disease is a common surgical problem requiring cholecystectomy. It is known to produce diverse histopathological changes in the gallbladder ranging from acute or chronic inflammation to metaplasias and even malignancies. Objective: The aim of this study was to emphasize the importance of a detailed microscopic examination and to study the range of histopathological lesions in cholecystectomy specimens. Methods: This is a retrospective study of 1200 cholecystectomy specimens received in the Department of Pathology, Jahurul Islam Medical College Hospital (JIMCH) over a peri

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Maithel, Shishir K., Sung Chul Hong, Cecilia Grace Ethun, et al. "Optimal perioperative therapy for incidental gallbladder cancer (OPT-IN): A randomized phase II/III trial—ECOG-ACRIN EA2197." Journal of Clinical Oncology 41, no. 4_suppl (2023): TPS620. http://dx.doi.org/10.1200/jco.2023.41.4_suppl.tps620.

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TPS620 Background: Gallbladder carcinoma (GBC) is a rare disease with a poor prognosis, with an overall estimated 5-year survival rate of 5-13%. Approximately 70% of gallbladder cancers in the US are found incidentally on pathologic analysis after elective cholecystectomy for presumed benign disease. Current management guidelines for incidental gallbladder cancer (IGBC) recommend re-resection for T1b, T2, and T3 lesions, which entails a partial hepatectomy and lymph node dissection. Up to 75% of patients have residual locoregional disease and 20% have disseminated disease at the time of re-res

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Poudel, Rajesh, and Anita Shah. "Incidence of Incidental Gall Bladder Cancer and Role of Routine Histopathological Examination in Cholecystectomies Specimens for Benign Disease." Journal of Nepal Health Research Council 18, no. 3 (2020): 547–50. http://dx.doi.org/10.33314/jnhrc.v18i3.1974.

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Background: Gallbladder cancer is the most common biliary tract cancer. Incidence rate of gall bladder cancer varies worldwide. Most of the patient with gall bladder cancer remained asymptomatic until late. Preoperative early diagnosis of carcinoma of gallbladder is rare, occurring in fewer than 20% of patients. Role of routine histopathology for cholecystectomy specimen is debatable. Aim of this study is to find the incidence of incidental gall bladder cancer and determine whether routine histopathology of cholecystectomy specimen is required or not. Methods: This is a retrospective des

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Pyo, Jung-Soo, Byoung Kwan Son, Hyo Young Lee, Il Whan Oh, and Kwang Hyun Chung. "Incidental Carcinoma after Cholecystectomy for Benign Disease of the Gallbladder: A Meta-Analysis." Journal of Clinical Medicine 9, no. 5 (2020): 1484. http://dx.doi.org/10.3390/jcm9051484.

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This study aimed to determine the incidence and the prognosis of incidental carcinoma of the gallbladder (IGBC) after cholecystectomy through a meta-analysis. This meta-analysis included 51 studies and 436,636 patients with cholecystectomy. The incidence rate of IGBC after cholecystectomy was 0.6% (95% confidence interval (CI) 0.5–0.8%). The incidence rate of recent studies was not significantly different from those of past studies. The mean age and female ratio of the IGBC subgroup were not significantly different from those of the overall patient group. The estimated rates of IGBC were 13.0%

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Jayasundara, JASB, and WMM de Silva. "Histological assessment of cholecystectomy specimens performed for symptomatic cholelithiasis: routine or selective?" Annals of The Royal College of Surgeons of England 95, no. 5 (2013): 317–22. http://dx.doi.org/10.1308/003588413x13629960046471.

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Traditionally, all cholecystectomy specimens resected for symptomatic cholelithiasis were sent for histological evaluation. The objectives of such evaluation are to confirm the clinicoradiological diagnosis, identification of unsuspected findings including incidental gallbladder malignancy, audit and research purposes, and quality control issues. Currently, there is a developing trend to consider selective histological evaluation of surgical specimens removed for clinically benign disease. This article discusses the need for routine or selective histopathological evaluation of gallbladder spec

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Janardan Panthi, Ravi Acharya, Jeevan Adhikari, and Bishal Pokhrel. "Outcome of routine histo-pathological examination of gallbladder specimen followed by Elective Laparoscopic Cholecystectomy, Ghorahi, Dang, Nepal." Janaki Medical College Journal of Medical Science 12, no. 03 (2024): 67–72. https://doi.org/10.3126/jmcjms.v12i03.73976.

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Background & Objectives: Gall bladder disease is the one of the commonest surgical diseases which is encountered in the surgical department. Gall bladder stone is the commonest pathological condition which affects the gallbladder. Gallbladder carcinoma is a rare but highly lethal malignancy. Gallbladder carcinoma is highly challenging for the health care professionals. This study evaluated the outcome of the routine histopathological examination of laparoscopic cholecystectomy specimens. Materials and Methods: This study was a retrospective observational study, conducted on 209 patients, w

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Alam, Rabiul, Swapan Kumar Sarkar, Subhasish Bandyopadhyay, Sudipta Chakrabarti, and Suman Ghosh. "Helicobacter Pylori and Metaplastic Changes in Chronic Cholecystitis: A Correlation Study." Perspectives in Medical Research 12, no. 2 (2024): 36–41. http://dx.doi.org/10.47799/pimr.1202.07.

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Abstract Introduction: Various types of metaplastic changes, such as gastric metaplasia (foveolar type or antral type) and intestinal metaplasia, are observed in chronic cholecystitis but not in normal mucosa. Helicobacter species can be detected in the bile and gallbladder tissue of patients with benign gallbladder disease. Objective: The present study aimed to observe the correlation between chronic cholecystitis and the presence of Helicobacter pylori as well as the different types of metaplastic changes in gallbladder mucosa. Materials and Methods: This descriptive, observational study was

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Radkiewicz, Cecilia, Jonas F. Ludvigsson, Ernesto Sparrelid, and Louise Emilsson. "Panacreatic cancer risk after benign gallbladder disease: A Swedish population-based cohort study." European Journal of Cancer 214 (January 2025): 115140. http://dx.doi.org/10.1016/j.ejca.2024.115140.

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