Relevant bibliographies by topics / Benzimidazole; 1

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Benzimidazole; 1'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Benzimidazole; 1"

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Krishnamurthy, Naik, and Narashimaiah Shashikala. "Synthesis of ruthenium(II) carbonyl complexes with 2-monosubstituted and 1,2-disubstituted benzimidazoles." Journal of the Serbian Chemical Society 74, no. 10 (2009): 1085–96. http://dx.doi.org/10.2298/jsc0910085k.

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The reaction of the polymeric carbonyl complex [RuCl2(CO)2]x with 2-monosubstituted and 1,2-disubstituted benzimidazoles and 1,4-bis(benzimidazol- 2-yl)benzene (L9) in 2-methoxyethanol produces various coloured complexes of the formulae [Ru(CO)2Cl2(L)2]?xH2O (L = 1-(o-hydroxybenzyl)-2-(o-hydroxyphenyl)benzimidazole (L1), 1-(o-hydroxyphenyl)benzimidazole (L4), 1-(p-hydroxyphenyl)benzimidazole (L5), 1-(p-chlorobenzyl)-2-p-chlorophenyl) benzimidazole (L7), 1-[1-(dimethylamino)benzyl]-2-[1-(dimethylamino) phenyl]benzimidazole (L10), x = 0; L = 2-benzylbenzimidazole (L8), 1,4-bis(benzimidazol-2-yl)
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Al-Warhi, Tarfah, Mohamed Said, Mahmoud El Hassab, et al. "Unexpected Synthesis, Single-Crystal X-ray Structure, Anticancer Activity, and Molecular Docking Studies of Certain 2–((Imidazole/Benzimidazol–2–yl)thio)–1–arylethanones." Crystals 10, no. 6 (2020): 446. http://dx.doi.org/10.3390/cryst10060446.

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In connection with our research program concerning development of novel effective benzimidazole-based anticancer candidates, herein we describe a new unexpected synthetic route to obtain a series of 2–((imidazole/benzimidazol2–yl)thio)1–arylethanones endowed with promising anti-breast cancer and Cyclin-dependent kinase 2 (CDK2) inhibitory activities. Contrary to expectations, products for the reaction of 2–mercaptoimidazole/benzimidazole 2a,b with β–keto esters 6a–c were unambiguously assigned as 2–((imidazol/benzimidazol2–yl)thio)1–arylethanones 10a–f based on NMR spectroscopy and single-crys
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Külen, Seda, and Sebla Dincer. "Evaluation of the effects of some benzimidazole derivatives on germination parameters of wheat varieties." Journal of Agricultural Sciences, Belgrade 69, no. 2 (2024): 121–34. http://dx.doi.org/10.2298/jas2402121k.

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This study aims to investigate the effect of some benzimidazole derivatives on the germination parameters of bread and durum wheat varieties. These derivatives contain both unsubstituted and substituted benzimidazole structures to determine the effect of the substituents on germination. Three different durum wheat varieties (?e?it-1252, Eminbey, and K?z?ltan-91) and three different bread wheat varieties (Demir 2000, Bayraktar 2000, and Tosunbey) were used in the study. First, 1H-benzimidazole (1) and 5-nitro-1H-benzimidazole (2) compounds were used to synthesize dinitro compounds (5,6-dnitro-1
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Geiger, H. Cristina, Patricia L. Zick, William R. Roberts, and David K. Geiger. "Synthesis and characterization of a novel long-alkyl-chain ester-substituted benzimidazole gelator and its octan-1-ol solvate." Acta Crystallographica Section C Structural Chemistry 73, no. 4 (2017): 350–56. http://dx.doi.org/10.1107/s2053229617004314.

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The synthesis of a novel benzimidazole derivative with a long-chain-ester substituent, namely methyl 8-[4-(1H-benzimidazol-2-yl)phenoxy]octanoate, (3), is reported. Ester (3) shows evidence of aggregation in solution and weak gelation ability with toluene. The octan-1-ol solvate, methyl 8-[4-(1H-benzimidazol-2-yl)phenoxy]octanoate octan-1-ol monosolvate, C22H26N2O3·C8H18O, (4), exhibits a four-molecule hydrogen-bonded motif in the solid state, with N—H...O hydrogen bonds between benzimidazole molecules and O—H...N hydrogen bonds between the octan-1-ol solvent molecules and the benzimidazole un
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Zaderenko, P., M. S. Gil, P. López, P. Ballesteros, I. Fonseca, and A. Albert. "Diethyl 2-Benzimidazol-1-ylsuccinate–Picric Acid (1/1) – An Inclusion Molecular Complex." Acta Crystallographica Section B Structural Science 53, no. 6 (1997): 961–67. http://dx.doi.org/10.1107/s0108768197008562.

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The crystal structure of the diethyl 2-benzimidazol-1-ylsuccinate–picric acid (1/1) molecular complex has been determined by X-ray diffraction analysis. Diethyl 2-benzimidazol-l-ylsuccinate molecules form channels along the a axis, in which the picric acid molecules are located. The benzimidazole moiety and the phenol group are held together by hydrogen bonding between the hydrogen of the phenol and the N3 atom of benzimidazole. Additionally, this hydrogen forms an intramolecular hydrogen bond with one O atom of the ortho-nitro group, thus producing a bifurcated hydrogen bond. 1H NMR spectra i
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Nardi, Monica, Sonia Bonacci, Natividad Herrera Cano, Manuela Oliverio, and Antonio Procopio. "The Highly Efficient Synthesis of 1,2-Disubstituted Benzimidazoles Using Microwave Irradiation." Molecules 27, no. 5 (2022): 1751. http://dx.doi.org/10.3390/molecules27051751.

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The benzimidazole ring of the heterocyclic pharmacophores is one of the most widespread and studied systems in nature. The benzimidazole derivative synthesis study is a crucial point for the development of a clinically available benzimidazole-based drug. Here, we report a simple microwave assisted method for the synthesis of 1,2-disubstituted benzimidazoles. The combination of the molar ratio of N-phenyl-o-phenylenediamine:benzaldehyde (1:1) using microwave irradiation and only 1% mol of Er(OTf)3 provides an efficient and environmental mild access to a diversity of benzimidazoles under solvent
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Poddar, Saikat Kumar, Nazmus Saqueeb, and SM Abdur Rahman. "Synthesis and Biological Evaluation of 2-methyl-1Hbenzimidazole and 1H-benzimidazol-2-yl-methanol." Dhaka University Journal of Pharmaceutical Sciences 15, no. 1 (2016): 83–87. http://dx.doi.org/10.3329/dujps.v15i1.29201.

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Two benzimidazole derivatives namely 2-methyl-1H-benzimidazole (1) and 1H-benzimidazol-2- ylmethanol (2) were synthesized in high yields by condensing O-phenylenediamine with two different carboxylic acid derivatives: glacial acetic acid and glycolic acid, following a different synthetic protocol. Structures were elucidated by spectroscopic methods. Among the two benzimidazole derivatives synthesized, 2-methyl-1Hbenzimidazole (1) showed moderate antioxidant activity with IC50 values of 144.84?g/ml whereas 1H-benzimidazol- 2-ylmethanol (2) displayed mild antioxidant activity (IC50 value 400.42
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Cikalov, V., V. Cikalova, A. Poddubov, and U. Guseynova. "SYNTHESIS AND POTENTIAL BIOLOGICAL ACTIVITY OF ANALOGUES OF THE DIBAZOL." Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry 10, no. 3 (2024): 334–40. https://doi.org/10.29039/2413-1725-2024-10-3-334-340.

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The synthesis of benzimidazole derivatives, similar to dibazole, was carried out using two methods. According to the first, 1, 2-Phenylenediamine condensed with excess quantity of 2-chlorophenylacetic acid in the presence of orthoboric acid at a temperature of 150 °C. After treatment and crystallization, the yield of 2-(2-chlorobenzyl)-1H-benzimidazole was 36 %. In the second method, 1, 2-phenylenediamine was reacted with an excess of phenoxyacetic acid and 1-naphthylacetic acid in the presence of orthoboric acid in an o-xylene solvent at boiling point. Thus, 2-(phenoxymethyl)-1H-benzimidazole
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Dölling, Wolfgang, Helmut Hartungb, and Matthias Biedermann. "Reaktionen von 2-Methyl-1H-benzimidazol mit Schwefelkohlenstoff und Phenylisothiocyanat. Kristall- und Molekülstruktur von 1,1′ -Carbonothioyl-bis(2-methyl-1H-benzimidazol) und 2-Methyl-1-(ethoxycarbonylmethylthio-phenylimino)-1H-benzimidazol / Reactions of 2-Methyl-1 H-benzimidazole with Carbon Disulfide and Phenyl Isothiocyanate. Molecular and Crystal Structures of 1,1′-Carbonothioyl-bis(2-methyl-1 H-benzimidazole) and 2-Methyl-1-(ethoxycarbonylmethylthio-phenylimino)-1 H-benzimidazole." Zeitschrift für Naturforschung B 50, no. 5 (1995): 837–43. http://dx.doi.org/10.1515/znb-1995-0525.

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Abstract 2-Methyl-1 H-benzimidazole 1 reacts in the presence of two equivalents of sodium hydride in dry DMSO with carbon disulfide to methyl 2-methylbenzimidazole-1-dithiocarboxylate 3 using methyl iodide as alkylating agent, whereas using 1,2-dibromoethane 1,1′-carbonothioyl bis(2-methyl-1 H-benzimidazole) 5 is formed. Compound 1 reacts with phenyl isothiocyanate in the presence of one equivalent of sodium hydride in dry DMF after alkylation to 2-methyl-1-( alkylthio-phenylimino)-1 H-benzimidazoles 6a, 6b. Reaction products 5 and 6b have been identified and structurally characterized by X-ra
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Sawant, Ramesh, and Deepali Kawade. "Synthesis and biological evaluation of some novel 2-phenyl benzimidazole-1-acetamide derivatives as potential anthelmintic agents." Acta Pharmaceutica 61, no. 3 (2011): 353–61. http://dx.doi.org/10.2478/v10007-011-0029-z.

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Synthesis and biological evaluation of some novel 2-phenyl benzimidazole-1-acetamide derivatives as potential anthelmintic agentsThe present study describes synthesis of a series of 2-phenyl benzimidazole-1-acetamide derivatives and their evaluation for anthelmintic activity using Indian adult earthworms,Pheretima posthuma.The structure of the title compounds was elucidated by elemental analysis and spectral data. The compounds 4-({[2-(4-nitrophenyl)-1H-benzimidazol-1-yl]acetyl}amino) benzoic acid (3a),N-ethyl-2-[2-(4-nitrophenyl)-1H-benzimidazol-1-yl] acetamide (3c),N-benzyl-2-[2-(4-nitrophen
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Dissertations / Theses on the topic "Benzimidazole; 1"

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Namal, Imge. "Synthesis And Electrochemical Studies Of Fluorene And Benzimidazole Containing Conjugated Polymers." Master's thesis, METU, 2013. http://etd.lib.metu.edu.tr/upload/12615382/index.pdf.

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The synthesis and characterization of two donor acceptor type conjugated polymers were investigated. The electrochemical properties were examined using cyclic voltammetry, spectroelectrochemistry and kinetic studies. The increase in the alkyl chain length attached to the fluorene unit was investigated by the corresponding electrochemical characteristics. The synthesis was carried out via Stille coupling of 4,7- dibromo-4&#039<br>-(tert-butyl)spiro[benzo[d]imidazole-2,1&#039<br>cyclohexane] and 2,5- bis(tributylstannyl)thiophene with 9,9-dihexyl-9H fluorene and 9,9-didodecyl-9H fluorene respect
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Barsys, Vygantas. "Benzimidazolų ir dihidropiridinų poveikio kraujagyslių segmentų ir papiliarinių raumenų izometrinei funkcijai įvertinimas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2013~D_20140106_083915-09957.

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Šio eksperimentinio darbo tikslas buvo įvertinti 1,4-dihidropiridino ir benzimidazolo junginių poveikį jūros kiaulyčių širdies papiliarinių raumenų izometrinei funkcijai bei žmogaus kraujagyslių segmentų susitraukimui ir atsipalaidavimui. Buvo atlikti eksperimentiniai tyrimai su izoliuotais jūros kiaulyčių širdies papiliarinių raumenų preparatais ir izoliuotais žmogaus v.saphena magna ir a.thoracica interna kraujagyslių segmentais. Kraujagyslių preparatai gauti iš pacientų, kuriems buvo atliekamos širdies vainikinių arterijų jungčių suformavimo operacijos LSMU ligoninės Kauno klinikos Kardioch
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Huang, Shih-Huang. "Synthesis and characterization of 2-chloro-3-benzylthiopyrrolo[1,2-a]- benzimidazol-1-one and 2,3-di(benzylthio)pyrrolo[1,2-a]benzimidazol-1-one." Thesis, University of North Texas, 2003. https://digital.library.unt.edu/ark:/67531/metadc4415/.

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The reaction between o-phenylenediamine and 2,3-dichloromaleic anhydride has been probed and found to give 2,3-dichloropyrrolo[1,2-a]- benzimidazol-1-one as the major product. Chlorine substitution in 2,3-dichloropyrrolo[1,2-a]benzimidazol-1-one by added benzylthiol occurs in the presence of pyridine to provide the corresponding monosulfide and disulfide derivatives. The first benzylthiol ligand undergoes reaction at the C-3 position of the five-membered pyrrolo-1-one ring, with the addition of the second benzylthiol ligand occurring at the remaining chlorine-substituted carbon. The mono- and
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Cerda, Cavieres Christopher David. "Síntesis de Derivados N-Benzoil-2-(2-Nitrofenil)-1-Hbenzimidazoles. Desarrollo de Metodologías Analíticas y Caracterización Fisicoquímica de N-(p-Flúor)-Benzoil-2-(2-Nitrofenil)-Benzimidazol y N-(p-Nitro)-Benzoil -2-(2 Nitrofenil)-Benzimidazol." Tesis, Universidad de Chile, 2008. http://repositorio.uchile.cl/handle/2250/105700.

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La presente Memoria se orientó al estudio y caracterización electro-analítica de una serie de derivados N-(4-R-benzoil)-2-(2-nitrofenil)-1-H-benzimidazoles como sustratos de interés biológico. Los compuestos estudiados fueron sintetizados a partir de 2-(o-nitrofenil)-benzimidazol, generado por condensación entre 1,2-diamino-benceno y 2-nitrobenzaldehído. Posterior reacción del benzimidazol con una serie de cloruros de aroílo, generó la serie de cuatro N-(4-R-benzoil)-2-(2-nitrofenil)-1-H-benzimidazoles en buen rendimiento (R = NO2, Cl, F), con la excepción del producto denominado PMNB (R =
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Wu, Guanmin. "Synthesis and Characterization of 2,3-Dichloropyrrolo[1,2-a]benzimidazol-1-one and Its Methylthiol Derivatives." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5238/.

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Condensation of 2,3-dichloromaleic anhydride and o-phenylenediamine in refluxing toluene affords the three compounds 2,3-dichloro-N-o-C6H4(NH2)maleimide (1), N,N¢-o-C6H4-bis(2,3-dichloromaleimide) (2), and 2,3-dichloropyrrolo[1,2-a]benzimidazol-1-one (3), with compound 1 as the major product. Repeating the same reaction in the presence of added PTSA furnishes compound 3 as the major product. Treatment of 3 with methylthiol in the presence of pyridine affords monosulfide compounds 2-chloro-3-methylthiopyrrolo[1,2-a]benzimidazol-1-one (4) and and the disulfide derivatives 2,3-di(methylthio)pyrro
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Zaher, Damien. "Early transition metal benzimidazolyl-based catalysts for olefin polymerisation and co-polymerisation." Thesis, Imperial College London, 2007. http://hdl.handle.net/10044/1/8352.

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Taleb, Abbass. "Recherche de composés antiparasitaires : voie d'accès aux 1-alkylbenzimidazole-4,7-diones et synthèse régiospécifique d'imidazo[4,5-g]quinoléine-4,9-diones." Lyon 1, 2005. http://www.theses.fr/2005LYO10293.

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Le thème de recherche développé dans ce mémoire est orienté vers la synthèse de produits potentiellement actifs contre un protozoaire intracellulaire : Toxoplasma gondii. La purine nucléoside phosphorylase (PNP) étant une enzyme indispensable au développement de ce parasite, une recherche de composés inhibiteurs de celle-ci a été initiée. Des dérivés de benzimidazole-4,7-diones ont alors montré une bonne activité dans ce domaine. La première phase de nos travaux a consisté à améliorer la voie d'accès à de tels composés. Ainsi une nouvelle méthodologie a été mise au point, qui permet d'accéder
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Ishak, Dridi Islem. "Synthèse stéréosélective et réactivité des 4-hydroxy-1-boryl-1-allénylsilanes. Synthèse et étude théorique de nouveaux dérivés de dimères benzimidazolo-1,3,5,2-triazaphosphorine-2-oxydes." Thesis, Sorbonne université, 2019. https://accesdistant.sorbonne-universite.fr/login?url=http://theses-intra.upmc.fr/modules/resources/download/theses/2019SORUS573.pdf.

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Cette thèse a portée sur deux sujets différents. D’abord la synthèse des 1-silylalléneboranes a été étudiée, pour la première fois, à partir d’époxyde acétylénique et d’un silylborane. Cette méthode permet la préparation stéréosélective et stéréospécifique des allénylboranes via un mécanisme SNi anti. Par la suite, la propargylation des aldéhydes par l’intermédiaire de ces allènes a permis d’accéder de façon stéréosélective aux 2-alcynyldiols-1,3 correspondants. Un état de transition fermé à six chainants a été proposé pour cette dernière transformation qui procède via un mécanisme SE2’. L’éte
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Badarau, Eduard. "Conception, synthèse et évaluation biologique de nouvelles classes de ligands sérotoninergiques 5-HT7." Phd thesis, Université d'Orléans, 2009. http://tel.archives-ouvertes.fr/tel-00480279.

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Parmi tous les neurotransmetteurs identifiés à ce jour, la sérotonine (5-hydroxytryptamine, 5-HT) est impliquée dans le système le plus complexe de récepteurs. Parmi eux, les récepteurs 5-HT7 qui sont les derniers découverts (1993) semblent avoir des implications multiples tant au niveau central que périphérique. Le potentiel thérapeutique représenté par la découverte de ligands 5-HT7 sélectifs vis-à-vis d'autres RCPGs a motivé notre projet de recherche. Nos études sont orientées vers la conception de trois classes distinctes de ligands. Une première famille à été conçue sur une charpente benz
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Gulart, Caroline Almeida. "Sensibilidade in vitro e in vivo de isolados de Colletotrichum lindemuthianum (Sacc & Magn.) Briosi & Cav., a fungicidas sistêmicos." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/4991.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>The sensitivity of ten isolated of Colletotrichum lindemuthianum the systemic fungicides was evaluated in vitro and in vivo, in experimental design was completely random with three replications. In the study in vitro, it was evaluated the percentage of germination of spores of the fungus when submitted to the benzimidazol fungicides: carbendazin and methyl tiophanate and the estrobilurins: azoxystrobin and pyraclostrobina. The methodology consisted in incorporate the fungicide to the agar at the final concentrations of 0; 0,1; 1,0;
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Books on the topic "Benzimidazole; 1"

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Preston, P. N. Benzimidazoles and Cogeneric Tricyclic Compounds, Part 1. Wiley & Sons, Incorporated, John, 2008.

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Benzimidazoles and Cogeneric Tricyclic Compounds, Part 1. Wiley & Sons, Incorporated, John, 2009.

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Book chapters on the topic "Benzimidazole; 1"

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Shaw, Gordon. "The Synthesis and Chemistry of Imidazole and Benzimidazole Nucleosides and Nucleotides." In Chemistry of Nucleosides and Nucleotides. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4757-9667-4_4.

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Chulay, Jeffrey, Karen Biron, Laurene Wang, et al. "Development of Novel Benzimidazole Riboside Compounds for Treatment of Cytomegalovirus Disease." In Antiviral Chemotherapy 5. Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4743-3_12.

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Byard, Edward H., and Keith Gull. "Molecular and Cellular Aspects of the Interaction of Benzimidazole Carbamate Pesticides with Microtubules." In The Cytoskeleton. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2161-3_6.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of praseodymium(III) complex with bidentate biheterocyclic 1-methyl-2-(2-pyridyl)benzimidazole ligand." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_637.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of neodymium(III) complex with bidentate biheterocyclic 1-methyl-2-(2-pyridyl)benzimidazole ligand." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_648.

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Nagase, H., and C. Y. Wang. "Comparison of Anti-genotoxic Activities of Dibenzoylmethane, 1,3-Indandione and 2-(Methylmercapto)benzimidazole in Bacteria and Human Cells." In Nitroarenes. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4615-3800-4_34.

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Gribble, Gordon W., Sudipta Roy, and Sujata Roy. "Fluorinated Imidazoles and Benzimidazoles." In Fluorine in Heterocyclic Chemistry Volume 1. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04346-3_8.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex with 2,4,4-trimethyl-1,5,9-triazacyclododec-1-ene and benzimidazole-2-thione ligand." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54234-7_10.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of nickel(II) complex with 2,4,4,9-tetramethyl-1,5,9-triazacyclododec-1-ene and benzimidazole-2-thione ligands." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-54234-7_14.

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Fraker, Lesa D., Jennifer Van Eyk, and R. John Solaro. "Reversal of phosphate induced decreases in force by the benzimidazole pyridazinone, UD-CG 212 CL, in myofilaments from human ventricle." In The Cellular Basis of Cardiovascular Function in Health and Disease. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5765-4_11.

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Conference papers on the topic "Benzimidazole; 1"

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Obot, Ime. "New Benzimidazole Derivatives as Corrosion Inhibitors for Carbon Steel in HCl Solution." In CORROSION 2015. NACE International, 2015. https://doi.org/10.5006/c2015-05941.

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Abstract The corrosion inhibtion behaviour of two new benzimidazole derivatives namely 2-(2-Bromophenyl)-1H-benzimidazole (BPBA) and 2-(2-Bromophenyl)-1-methyl-1H-benzimidazole (BPMA) on carbon steel in 0.5 M HCl solution was investigated using electrochemical methods such as potentiodynamic polarization sweeps (Tafel plots) and electrochemical impedance spectroscopy (EIS). Scanning electron microscopy (SEM), attenuated total reflectance Fourier transformed infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS) and contact angle techniques were carried out to established the
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Arnautova, A. O., I. A. Aleksakhina, A. L. Kayushin, and I. D. Konstantinova. "NEW BENZIMIDAZOLE NUCLEOSIDES." In OpenBio-2023. ИПЦ НГУ, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-46.

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Modified nucleosides are one of the most important classes of antimetabolites actively used in practical medicine as antiviral and antitumor drugs. There are two main methods of producing nucleoside analogs: chemical and enzymatic. The purpose of this study is to develop an efficient method for the preparation of new benzimidazole nucleosides by enzymatic synthesis.
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Pimenov, I. A. "THE USE OF MOLECULAR GENETIC METHODS TO DETECT HOMO- AND HETEROZYGOUS ALLELES OF THE β-TUBULIN GENE IN PARASITIC NEMATODES HAEMONCHUS CONTORTUS". У THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. VNIIP – FSC VIEV, 2025. https://doi.org/10.31016/978-5-6053355-1-1.2025.26.244-249.

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The article presents data on the use of molecular genetic tests to diagnose the occurrence of mutant alleles in the β-tubulin gene in parasitic nematodes Haemonchus contortus that lead to the formation of genetically determined resistance to benzimidazoles. The studies were conducted on parasitic nematodes isolated from the gastrointestinal tracts of sheep raised in the Stavropol Territory and the Republic of Ingushetia. On these sheep farms, regular deworming of the entire small cattle with benzimidazole preparations was carried out. To establish the taxonomic affiliation of the studied helmi
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Zhuravlev, A. M., V. V. Aksenov, V. N. Gavrilyuk, A. B. Golovanov, and I. V. Ivanov. "ALLOSTERIC INHIBITORS OF ALOX15 BASED ON LIGANDS PROVIDING MULTIDIRECTIONAL REGULATION OF LINOLEIC AND ARACHIDONIC ACIDS." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-76.

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Mammalian 15-lipoxygenases (ALOX15) are enzymes of lipid peroxidation. The pathophysiological role of ALOX15 metabolites, linoleic acid and arachidonic acid derivatives, has made this enzyme a target for pharmacological studies. Several indole and benzimidazole derivatives inhibit the activity of ALOX15 in a substrate-specific manner, but the molecular basis of this allosteric inhibition remains unclear.
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Romero-Parra, J., C. F. Lagos, C. Espinosa-Bustos, J. Mella-Raipán, C. D. Pessoa-Mahana, and Recabarren G. "Synthesis and docking of new benzimidazole derivates designed as novel and potent CB1 cannabinoid ligands." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0171-1.

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V, DAMILOLA, OLAYINKA O, OLAYINKA O, OLUWATOSIN Y, and YUXIA ZHAO. "Facile synthesis of N substituted 2 3 5 dinitrophenyl benzimidazole derivatives for antimicrobial investigation." In Seventh International Conference on Advances in Applied Science and Environmental Engineering - ASEE 2017. Institute of Research Engineers and Doctors, 2017. http://dx.doi.org/10.15224/978-1-63248-125-2-07.

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Yang, Jiang, Xu Chen, and Xilin Jia. "Benzimidazole Derivative and its Mixture as Novel Corrosion Inhibitors for Carbon Steel in High-Pressure Supercritical CO2 Environment." In SPE International Conference on Oilfield Chemistry. SPE, 2025. https://doi.org/10.2118/224323-ms.

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Abstract The carbon capture, utilization, and storage (CCUS) process plays a crucial role in reducing carbon dioxide (CO2) emissions. Additionally, CCUS-enhanced oil and gas recovery (CO2-EOR) is widely used. During CCUS process, CO2 exists in the downhole tubing as a supercritical (SC) fluid under high pressure. Severe corrosion occurs in the presence of water in supercritical CO2 environments. Corrosion inhibitors are among the most economical cost-effective methods for controlling corrosion. However, most conventional corrosion inhibitors are ineffective to control corrosion in high-pressur
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Filho, Everton Chaves Correia, and Lia Camurça Costa. "RESISTÊNCIA DE HELMINTOS AOS BENZIMIDAZÓLICOS: UMAREVISÃO DE LITERATURA." In II Congresso Brasileiro de Parasitologia Humana On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbrapah/32.

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Introdução: Em 2010, registrou-se cerca de 1 bilhão de casos de doenças causadas por helmintos no mundo. Diante disso, a Organização Mundial da Saúde (OMS) sugeriu a quimioprofilaxia periódica como tratamento preventivo de verminoses. A principal classe medicamentosa utilizada são os anti-helmínticos benzimidazólicos, que se mostraram eficazes no tratamento de verminoses, mas com potencial limitado em algunscasos. Logo, surgiu a hipótese de que uma exposição prolongada a tais drogas seria capaz de selecionar helmintos mais resistentes. Objetivos: 1) Compreender o mecanismo de ação dos benzimid
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Nitone, Umesh, Jayaveersinh Mahida, Seema Agrawal, and Ravi Patel. "Silica supported copper nano particles design from metal waste apply formation of various condensation reaction." In 7th GoGreen Summit 2021. Technoarete, 2021. http://dx.doi.org/10.36647/978-93-92106-02-6.9.

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In recent years organic chemist focused on green chemistry for organic synthesis transformations because the silica supported catalyst is more stable, efficient and easy to recover and reusable after reaction. The silica supported copper catalyst is design from E-Waste, It used for formation of benzimidazoles from diamines and aldehydes.it is very deep work done by various catalyst, we noted in our research in unique method develop for synthesis of benzimidazoles made by condensation diamine and aldehydes via silica supported copper nano particles under EtOH as reaction media . The reactions d
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Li, Yonghe, Patsy G. Oliver, Wenyan Lu та ін. "Abstract 5173: Discovery of a series of benzimidazoles as potent Wnt/β-catenin signaling inhibitors in colorectal cancer cells". У Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5173.

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Reports on the topic "Benzimidazole; 1"

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Alwagdani, Abdullah. Review Of mPGES-1 Inhibitors Based On The Benzoxazole And Its Isostere Scaffold For The Treatment Of Inflammatory Diseases. University of Tennessee Health Science Center, 2024. http://dx.doi.org/10.21007/com.lsp.2024.0021.

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The vital role of the prostanoid pathway in inflammation, pain, cancer, Alzheimer’s and many other diseases has attracted the drug discovery community to discover targets for therapeutic development. Although existing non-steroidal anti-inflammatory drugs (NSAIDs) inhibiting cyclooxygenases (COX) are widely used, the side effects of these NSAIDs limit the ling time medication. Microsomal prostaglandin E synthase-1 (mPGES-1) is an attractive target that is overexpressed during inflammations, and it could be a safe alternative to NSAIDs for treating inflammatory diseases.Since the discovery of m
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