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Relevant bibliographies by topics / Benzimidazoles – Synthesis

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Dissertations / Theses

Academic literature on the topic 'Benzimidazoles – Synthesis'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Dissertations / Theses on the topic "Benzimidazoles – Synthesis"

1

Azmus, Dora J. Taylor. "Synthesis of polybenzimidazoles from monomers containing flexible linkages." Thesis, Corvallis, Oregon : Oregon State University, 1992. http://handle.dtic.mil/100.2/ADA256976.

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Thesis (M.S.)--Oregon State University, 1993.<br>Description based on title screen as viewed on April 8, 2009. "Completed 13 May 1992, Commencement June 1993." Includes bibliographical references (p. 73-75). Also available in print.

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2

Robinson, A. G. "Synthesis and reactions of 2H-benzimidazoles." Thesis, University of Salford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.356186.

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3

Wathey, William B. "The synthesis of benzimidazoles of medicinial interest." Thesis, Cardiff University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329643.

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The aim of this programme was to design and synthesize triazinobenzimidazoles that are analogous to the antihypertensive agents, hydralazine and dihydralazine. Retrosynthetic analysis of these analogues showed that the key intermediates in the synthesis were the novel [1,2,4]triazino[4,5-a]benzimidazol-l-ones and the related 1,4-diones. Existing routes to this tricyclic ring system were either limited in scope or needed expensive starting materials. Therefore, a new synthetic route to these compounds was developed using the readily available 2-acylbenzimidazoles as starting materials. These ac

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4

Bowles, Steven E. "Synthesis and characterization of annelated nitronyl nitroxides /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/11611.

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5

Taylor, S. L. "An investigation of catalysis in the Ladenburg synthesis of benzimidazoles." Thesis, Manchester Metropolitan University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233017.

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6

Wahedy, Kanan Mahmoud. "Methodology for synthesis of novel bis-and oligo (benzimidazoles)." Thesis, University of Manchester, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684999.

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7

Hubbard, Jeremiah W. "Synthesis of substituted 2-vinyl and 2-phenylbenzimidazoles and progress towards the synthesis of natural products ht-13-A and ht-13-B." Morgantown, W. Va. : [West Virginia University Libraries], 2008. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=6051.

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Thesis (Ph. D.)--West Virginia University, 2008.<br>Title from document title page. Document formatted into pages; contains xi, 179 p. : ill. Includes abstract. Includes bibliographical references (p. 88-94).

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8

Hazelton, J. C. "Reactions of 2H-benzimidazoles and synthesis of some potential anthelmintics." Thesis, University of Salford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234629.

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9

Khan, Aqeel Ahmad. "Synthesis of novel oligomeric bis-benzimidazoles for their biological evaluation." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/synthesis-of-novel-oligomeric-bisbenzimidazoles-for-their-biological-evaluation(769832e2-2892-4bcb-b739-8929b4da5ca8).html.

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Benzimidazoles are heterocyclic compounds. Symmetrical and unsymmetrical benzimidazoles/oligomers are minor groove DNA sequence selective binding compounds. Distamycin A and netropsin are examples of naturally occurring DNA binders. Hoechst 33258 (Bis–benzimidazole) is a synthetic minor groove A-T sequence selective reagent and has in vivo activity by inhibiting the topoisomerase II enzyme. The targets in this research work were to synthesise extended analogues of Hoechst with structural modifications (amide bond) or amide-linked dimers with a view to identifying new potential ligands. To synt

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10

Alaqeel, Shatha. "Synthesis of novel dimeric and oligomeric benzimidazoles targeted to nucleic acid minor groove binding." Thesis, University of Manchester, 2010. https://www.research.manchester.ac.uk/portal/en/theses/synthesis-of-novel-dimeric-and-oligomeric-benzimidazoles-targeted-to-nucleic-acid-minor-groove-binding(5e5b7b9a-72fb-4941-80ec-0a28a3c1b098).html.

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Amido-oligopyrroles/imidazoles and dimeric benzimidazoles are heterocyclic compounds which are nucleic acid minor groove binding agents. The targets for this project were symmetrical and unsymmetrical amide-linked di- and tri- and tetrameric benzimidazoles to evaluate as potential DNA binding agents. Syntheses involved linkage between C2 and C5 positions of 2-carboxy, 5-carboxy or 2,5-dicarboxy and 2-amino, 5-amino or 2,5-diamino-bearing benzimidazoles. This matrix of substrates could be coupled directly C2-C5 by amide linkage, or these same precursors could also be dimerized symmetrically usi

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