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Dissertations / Theses on the topic 'Benzimidazolone'

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Published: 4 June 2021
Last updated: 15 February 2022

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1

Duffner, Jack Patrick. "Synthesis of Benzimidazolone Glucose Uptake Inhibitors." Ohio University Honors Tutorial College / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1524832705752963.

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2

Germain, A. L. "Some synthesis of benzimidazolone analogues of prostacyclin." Thesis, University of Greenwich, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380715.

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3

El, Gaghlab Khattab [Verfasser]. "Benzimidazolone und Benzimidazolthione als neue Modulatoren epigenetischer Prozesse / Khattab El Gaghlab." Greifswald : Universitätsbibliothek Greifswald, 2013. http://d-nb.info/1035605341/34.

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4

Badarau, Eduard. "Conception, synthèse et évaluation biologique de nouvelles classes de ligands sérotoninergiques 5-HT7." Phd thesis, Université d'Orléans, 2009. http://tel.archives-ouvertes.fr/tel-00480279.

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Parmi tous les neurotransmetteurs identifiés à ce jour, la sérotonine (5-hydroxytryptamine, 5-HT) est impliquée dans le système le plus complexe de récepteurs. Parmi eux, les récepteurs 5-HT7 qui sont les derniers découverts (1993) semblent avoir des implications multiples tant au niveau central que périphérique. Le potentiel thérapeutique représenté par la découverte de ligands 5-HT7 sélectifs vis-à-vis d'autres RCPGs a motivé notre projet de recherche. Nos études sont orientées vers la conception de trois classes distinctes de ligands. Une première famille à été conçue sur une charpente benz
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5

Karim, Rehana. "Development of radical synthetic methodology using solid-phase organic synthesis." Thesis, Loughborough University, 2003. https://dspace.lboro.ac.uk/2134/34406.

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The synthesis of heterocycles using radical intermediates has become an important area of research in recent years. The aim of our research was to develop radical methodologies to construct heterocycles on solid-support. Tri-cyclic benzimidazole derivatives are desirable synthetic targets with a range of biological activity and are part of certain anti-tumour agents. Solid-supported radical reactions with substituted benzimidazoles were performed under different experimental conditions, including different solvents, three different resins (Wang, Merrifield and Rink) and different radical reage
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6

Ritchie, Michael W. "Benzimidazole nucleoside analogues as potential antiherpetic agents." Thesis, University of St Andrews, 1997. http://hdl.handle.net/10023/14245.

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7

White, Wade M. "Synthesis and photoluminescent properties of linear and starburst compounds based on benzimidazole, 2-(2'-pyridyl)benzimidazole and 2,2'-dipyridylamine." Thesis, Kingston, Ont. : [s.n.], 2007. http://hdl.handle.net/1974/495.

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8

Akpinar, Hava Zekiye. "Synthesis Of Benzimidazole Containing Donor Acceptor Electrochromic Polymers." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613006/index.pdf.

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ABSTRACT SYNTHESIS OF BENZIMIDAZOLE CONTAINING DONOR ACCEPTOR ELECTROCHROMIC POLYMERS Akpinar, Hava Zekiye M. Sc., Department of Chemistry Supervisor: Prof. Dr. Levent Toppare February 2011, 60 pages Donor-acceptor-donor (DAD) type benzimidazole (BIm) and 3,4-ethylenedioxythiophene (EDOT) bearing monomers (4-(2,3-Dihydrothieno[3,4-b][1,4]dioxin-5-yl)-7-(2,3 dihydrothieno[3,4b][1,4] dioxin-7-yl)-2-benzyl-1H-benzo[d]imidazole (M1), 2,4-bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-7-(2,3-dihydrothieno[3,4-b][1,4]dioxin-7-yl)-1H-benzo[d]imidazole (M2) and 4-(2,3-dihydrothieno[3,4-b][1
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9

Blakemore, Emily J. A. "Molecular genetics of benzimidazole resistance in Pseudocercosporella herpotrichoides." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276190.

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10

Ozelcaglayan, Ali Can. "Synthesis Of Electroactive Benzimidazole Derivatives And Their Electrochromic Properties." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12615196/index.pdf.

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In order to study their electrochemical and optical properties, two donor-acceptordonor (D-A-D) type monomers<br>4&#039<br>-(tert-butyl)-4,7-bis(4-hexylthiophen-2- yl)spiro[benzo[d]imidazole-2,1&#039<br>-cyclohexane] (BIHT) and 4&#039<br>-(tert-butyl)-4,7-bis(2,3- dihydrothieno[3,4-b][1,4]dioxin-5-yl)spiro[benzo[d]imidazole-2,1&#039<br>-cyclohexane] (BIED), were electrochemically polymerized. These properties were investigated by cyclic voltammetry and UV&ndash<br>Vis-NIR Spectroscopy techniques. Effects of different donor groups<br>3-hexylthiophene and 3, 4-ethylenedioxythiophene (EDOT), on n
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11

Scott, Elspeth Warren. "Effects of benzimidazole anthelmintics on nematode parasites of sheep." Thesis, University of Glasgow, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284783.

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12

Kimpel, Sandra [Verfasser]. "Der Effekt von Benzimidazolonen auf den epithelialen Natriumtransport der Lunge / Sandra Kimpel." Ulm : Universität Ulm. Medizinische Fakultät, 2013. http://d-nb.info/1038005337/34.

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13

Clark, Hannah Jane. "The molecular mechanisms of benzimidazole resistance in equine small strongyles." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441739.

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14

Robinson, M. W. "Mechanisms of benzimidazole resistance in the liver fluke, Fasciola hepatica." Thesis, Queen's University Belfast, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273381.

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15

Yilmaz, Seda. "Long Wavelength Photosensitizers With Benzotriazole And Benzimidazole Skeletons For Cationic Polymerization." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613457/index.pdf.

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Benzimidazole and benzotriazole derivatives, 4-(2,3-Dihydrothieno[3,4-b][1,4] dioxin-5-yl)-7-(2,3-dihydrothieno[3,4b][1,4]dioxin-7-yl)-2-benzyl-1H-benzo[d] imidazole (BIm-Ed), 2-benzyl-4,7-di(thiophen-2-yl)-2H-benzo[d] [1,2,3] triazole (BBTS), and 2-benzyl-4,7-bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-2Hbenzo[ d] [1,2,3] triazole (BBTES) were employed as photosensitizers for diaryliodonium salt photoinitiators in cationic photopolymerization of various epoxide and vinyl ether monomers. Diphenyliodonium hexafluorophosphate (Ph2I+PF6&macr<br>) salt was used as the photoinitiator in this stud
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16

Namal, Imge. "Synthesis And Electrochemical Studies Of Fluorene And Benzimidazole Containing Conjugated Polymers." Master's thesis, METU, 2013. http://etd.lib.metu.edu.tr/upload/12615382/index.pdf.

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The synthesis and characterization of two donor acceptor type conjugated polymers were investigated. The electrochemical properties were examined using cyclic voltammetry, spectroelectrochemistry and kinetic studies. The increase in the alkyl chain length attached to the fluorene unit was investigated by the corresponding electrochemical characteristics. The synthesis was carried out via Stille coupling of 4,7- dibromo-4&#039<br>-(tert-butyl)spiro[benzo[d]imidazole-2,1&#039<br>cyclohexane] and 2,5- bis(tributylstannyl)thiophene with 9,9-dihexyl-9H fluorene and 9,9-didodecyl-9H fluorene respect
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17

MacDonald, Louisa M. "Characterisation of the benzimidazole-binding site on the cytoskeletal protein tubulin." Murdoch University, 2003. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20050107.94048.

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The binding kinetics of several benzimidazole compounds were determined with recombinant tubulin monomers and heterodimers from benzimidazole-sensitive and -insensitive organisms. This study utilised the naturally occurring high efficacy of the benzimdazoles for the parasitic protozoa Giardia duodenalis and Encephalitozoon intestinalis. The benzimidazoles are not active against the protozoan Cryptosporidium parvum or mammalian hosts, including humans. The affinity of several benzimidazole derivatives for monomeric and heterodimeric â-tubulin was clearly demonstrated, thus supporting previous s
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18

Willis, Peter G. "DESIGNING MOLECULAR RECOGNITION IN THE CONTEXT OF HYDROGEN BONDING AND MOLECULAR DYNAMICS." UKnowledge, 2001. http://uknowledge.uky.edu/gradschool_diss/279.

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The effect of hydrogen bonding on the conformation of organic moleculesunifies two projects in this thesis. In one project, the stability of the intramolecularhydrogen bond in derivatives of 2-guanidinobenzimidazole was studied bydynamic 1H NMR spectrometry. The impact that this intramolecular hydrogenbond had on the bond order of the neutral guanidino group and on the dynamicconformation of these aromatic structures was related to the concept of hydrogenbond-assisted resonance. In another project, an oligomer possessing repetitiveconformation and capable of much inter- and intramolecular hydr
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19

Carvalho, Luísa da Conceição Costa Rainho de. "Development of novel benzimidazole- based COX Inhibitors new synthetic strategies and screening of heterocyclic structures." Doctoral thesis, Faculdade de Ciencias e Tecnologia, 2014. http://hdl.handle.net/10362/13142.

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20

Kaya, Deniz Tugba. "Solution Processable Benzotriazole, Benzimidazole And Biphenyl Containing Conjugated Copolymers For Optoelectronic Applications." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614753/index.pdf.

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The synthesis and optoelectronic properties of biphenyl based conjugated copolymers with varying acceptor units in the polymer backbone were investigated. The well known Donor-Acceptor Theory was used to establish the synthetic pathway for the structural modifications. Solubility issues regarding biphenyl polymer was solved by copolymerizing with soluble units. For this purpose<br>poly 4-(biphenyl-4-yl)- 4&rsquo<br>-tert butylspiro[benzo[d]imidazole-2,1&rsquo<br>-cyclohexane] (P1), poly 4-(biphenyl-4-yl)- 2- dodecyl-2H-benzo[d][1,2,3]triazole (P2) and poly(4-(5-(biphenyl-4-yl)-4-hexylthiophen-
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21

Lubega, George W. (George Willy). "Benzimidazole (BZ) resistance in Haemonchus controtus : specific interactions of BZs with tubulin." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=70203.

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The mechanism of benzimidazole (BZ) anthelmintic resistance in Haemonchus contortus was investigated. The total binding (TB), low-affinity binding (LAB) and high-affinity (specific) binding (HAB) of ($ sp3$H) BZs (mebendazole (MBZ), oxibendazole (OBZ), albendazole (ABZ) and oxfendazole (OFZ)) in supernatants derived from BZ-susceptible (S) and BZ-resistant (R) strains were examined and compared. The TB of all ($ sp3$H) BZs was reduced for the R strain. The TB of OBZ, MBZ and ABZ was separated into LAB and HAB. However, OFZ bound with low-affinity. The binding affinity, K$ sb{ rm a},$ and maxim
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22

Björk, Malin. "Synthesis of sulfur and seleniumn heterocycles, including derivatives of imidazopyridine and benzimidazole /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-597-6/.

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23

Lanusse, Carlos Edmundo. "Pharmacokinetics of propylthio-benzimidazole anthelmintics : modulation of liver biotransformation in sheep and cattle." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=70364.

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The aim of this research was to determine the influence of route of administration, drug formulation and modified-liver metabolism on the pharmacokinetic and metabolic patterns of benzimidazole anthelmintics in ruminants. Both route of administration and formulation dramatically affected the bioconversion of netobimin (NTB) pro-drug, N-methoxycarbonyl-N$ sp prime$-(2-nitro-5-propylphenylthio)-${ rm N} sp{ prime prime}$-(2-ethyl sulphonic acid) guanidine, and the bioavailability and disposition kinetics of its active albendazole (ABZ) metabolites in both sheep and cattle. The efficacy of NTB co
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24

Van, den Berg Isabel Dedrieka. "Inhibition of monoamine oxidase B by substituted benzimidazole analogues / Deidré van den Berg." Thesis, North-West University, 2006. http://hdl.handle.net/10394/1264.

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Both monoamine oxidase A and B (MAO-A and B) play an important role in the metabolism of monoamine neurotransmitters in the central nervous system (CNS) and are therefore of considerable pharmacological interest for the development of new drug therapies. Inhibitors of MA0 are of therapeutic interest for both the treatment of psychiatric and neurological diseases. Selective inhibitors of MAO-B are in use and are under investigation for the treatment of the symptoms and underlying neurodegeneration of Parkinson's disease (PD). PD is one of the most common neurological diseases of the elderly and
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25

El, Majzoub El Sabagh Abir. "Evaluation de ligands tétraazamacrocycliques porteurs de groupements benzimidazole pour le dosage de cations." Reims, 2008. http://theses.univ-reims.fr/sciences/2008REIMS024.pdf.

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L’objectif poursuivi au cours de ce travail est de développer des nouvelles sondes fluorescentes et de mettre à profit leurs propriétés en fluorescence pour titrer les cations, en particulier le Zn2+. Les ligands développés dans ce but sont des cyclen et cyclam monoN-fonctionnalisés par un groupement méthylbenzimidazole ainsi qu’un cyclen diN-fonctionnalisé par ce même groupement. Dans le cas des complexes de cyclen et cyclam monoN-fonctionnalisés, la présence d’atomes coordinants exomacrocycliques augmente la stabilité des complexes des métaux de transitions étudiés. Pour chacun des ligands m
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26

Boufatah, Narimène. "Synthèse et réactivité par transfert monoélectronique de nouvelles cibles pharmacologiques dérivées du benzimidazole." Aix-Marseille 2, 2004. http://www.theses.fr/2004AIX22958.

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27

Liu, Qingting. "Poly (2,5-benzimidazole) based polymer electrolyte membranes for high temperature fuel cell applications." Thesis, Loughborough University, 2010. https://dspace.lboro.ac.uk/2134/6933.

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Polymer electrolyte membrane fuel cells (PEMFCs) are one of the most promising clean technologies under development. However, the main obstacles for commercialising PEMFCs are largely attributed to the technical limitations and cost of current PEM materials such as Nafion. Novel poly(2,5-benzimidazole) (ABPBI)/POSS based polymer composite electrolyte membranes with excellent mechanical and conductivity properties were developed in this project including (I) ABPBI, polybenzimidazole (PBI) and their copolymers were synthesised by solution polymerisation and their chemical structures were confirm
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28

Sterz, Katja [Verfasser]. "Funktionelle Untersuchung von Benzimidazolen und Acridonsäureamiden als Modulatoren des ABC-Transporters ABCB1 / Katja Sterz." Bonn : Universitäts- und Landesbibliothek Bonn, 2013. http://d-nb.info/104497205X/34.

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29

Barrett, Martin. "Field studies on the control of a benzimidazole resistant isolate of Teladorsagia (Ostertagia) circumcincta." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360183.

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30

Gbadamassi, Moubachirou. "Nouveaux antiparasitaires dans la série du benzimidazole synthèse et évaluation de leur activité biologique." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb375978677.

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31

N'Diaye, Ibrahima. "Annélation du benzimidazole étude chimique et parasitologique des dérivés tricycliques et de leurs précurseurs." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb375999926.

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32

N'Diaye, Ibrahima. "Annelation du benzimidazole : étude chimique et parasitologique des dérivés tricycliques et de leurs précurseurs." Paris 11, 1986. http://www.theses.fr/1986PA112140.

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Ce travail a été réalisé dans le but d'obtenir des dérivés tricycliques du benzimidazole susceptibles d'avoir une activité antiparasitaire. L'étude chimique est présentée en quatre chapitres. Le premier consiste en la synthèse de chloro-2 benzimidazoles substitués en 1 par une chaîne fonctionnalisée. Les homologues nitrés au noyau benzénique ont également été préparés en raison du caractère pharmacophore antiparasitaire de ce substituant. Les autres chapitres portent sur les réactions des nucléophiles azotés ou oxygénés avec les chloro-2 benzimidazoles substitués en 1. Des benzimidazoles subst
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33

L'abbate, Fabrizio P. "Synthesis and investigation of benzimidazole and carbazole ß-haematin inhibiting scaffolds with antimalarial activity." Thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/28432.

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Chloroquine was one of the main malarial treatments until the late 1960s when resistance began to emerge. This antimalarial targets haemozoin formation which causes a cytotoxic accumulation of free haem in the malaria parasite leading to parasite death. This is still one of the most promising pathways for treatment of the most prevalent species of malaria parasite, Plasmodium falciparum to date but, owing to growing resistance to chloroquine and other current antimalarial drugs, there is a dire need for new drugs. One strategy is to investigate non-chloroquine haemozoin inhibitors. High-throug
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34

Alasmary, Fatmah A. S. "Synthesis and evaluation of selected benzimidazole derivatives as potential antimicrobial agents. An investigation into the synthesis of substituted benzimidazoles and their evaluation in vitro for antimicrobial activity." Thesis, University of Bradford, 2013. http://hdl.handle.net/10454/6325.

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Microbe resistence is a serious issue, especially as they have become resistant to most well known drugs. Therefore this is considered as a global problem and is now dealt with at a poitical level. Since no new classes of antimicrobial agents have been discovered in the past three deacdes, the development of new drugs is extremely urgent. Therefore the aim of this project was to synthesise derivatives of benzimidazole, and then assesses their antimicrobial activities in vitro by using disc (well) diffusion and MICs tests. A total of 69 benzimidazole derivatives, with substituents at pos
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35

Shingade, Vikas M. "Investigations of the Electronic and Molecular Structures of Luminescent Pt(II) and Pt(IV) Complexes with Triimine Ligands." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1460447231.

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36

Chehresa, Azita. "Benzimidazole-resistance and associated changes in life history traits of Heligmosomoides polygyrus (Nematoda) in mice." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=42002.

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Association between albendazole anthelmintic resistance and a panel of life history traits in Heligmosomoides polygyrus was investigated both prior to and during drug-selection. Associations prior to anthelmintic application were studied in ten independent lines isolated without drug treatment from a susceptible stock population by random genetic drift. Variation among lines was detected in several life history traits (i.e., establishment, development and survival), and, despite lack of previous exposure to albendazole, lines also varied in their tolerance to the drug. No significant correlati
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37

Chehresa, Azita. "Benzimidazole-resistance and associated changes in life history traits of Heligmosomoides polygyrus, Nematoda, in mice." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0026/NQ29909.pdf.

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38

Anhorn, Michael J. "Nitrogen Rich Porous Organic Frameworks: Proton Conduction Behavior of 3D Benzimidazole and Azo-linked Polymers." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5448.

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Nitrogen-rich porous organic frameworks show great promise for use as acid-doped proton conducting membranes, due to their high porosity, excellent chemical and thermal stability, ease of synthesis, and high nitrogen content. Aided by very high surface area and pore volume, the material has the ability to adsorb high amounts of H3PO4 into its network, which creates a proton rich environment, capable of facile proton conduction. The morphology and chemical environment, doping behavior, and proton conduction of these materials were investigated. With such high acid-doping, ex-situ studies reveal
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39

Shu, Chang-Ming, and 舒昌明. "Process Improvement and Property Studies of The Benzimidazolone Red Pigment." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/64489254779881353849.

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碩士<br>國立中正大學<br>化學工程研究所<br>90<br>PR176 is one of the Azo-benzimidazolone red pigments. It has excellent physical properties and is widely used in the plastic and paint industries. In general the manufacturing process comprises diazotization、coupling reaction to get α-type crystalline pigment, and pigmentation by a solvent or at a high temperature for converting into the β-type crystalline pigment. The expensive manufacturing cost because of the complicated multi-stage process has prompted us to improve the overall process. Our study results indicate that by choosing a specific mol
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40

Rossouw, Ingrid. "Transcriptional and genomic analyses reveal an analogous mechanism for a Piperidinyl-Benzimidazolone analog in Babesia divergens compared to other apicomplexans." Thesis, 2015. http://hdl.handle.net/2263/50769.

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Human babesiosis is a rapidly emerging, zoonotic, infectious disease causing potentially lifethreatening malaria-like symptoms in humans. Disease prevalence has escalated over the past 50 years from a few isolated cases to endemic areas now being recognized. Early disease detection, diagnosis and treatment with effective anti-babesiacidal compounds are vital for both human and animal health. In humans, Babesia parasites can be cleared by anti-malarials including atovaquone (with azithromycin) or quinine (plus clindamycin) but highly immunecompromised individuals respond poorly to these t
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41

Freitag, Marcus [Verfasser]. "Synthese 1,5-substituierter Benzimidazolone und Benzimidazolthione sowie N-substituierter 7-Chlorchinolin-4-amine zur Untersuchung ihrer biologischen Aktivität / vorgelegt von Marcus Freitag." 2010. http://d-nb.info/1008925543/34.

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42

Stibrany, Robert T. "Exploration of benzimidazole chemistry." 2008. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.17223.

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43

Pan, Pi-Chi, and 潘碧琪. "Liquid-Phase Combinatorial Synthesis of Arylamines, Arylpiperazines and Benzimidazolones." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/09705045687618632671.

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碩士<br>國立東華大學<br>化學研究所<br>87<br>A method for soluble, inexpensive polymer-supported synthesis of piperazine and piperidine libraries on the basis of nucleophilic aryl substitution (SNAr) and N-acylation is described. Asymmetric N, N*-disubstituted piperazine and piperidine derivatives, that are potential drug candidates, can be synthesized in quantitative yields and excellent purtity after several steps by simple precipitation and washing. This liquid phase method should prove to be a useful tool for constructing combinatorial libraries containing diamine moiety. In order to further
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44

Wang, Jui-Hsiung, and 王瑞雄. "Analysis of Benzimidazole Fungicides by Micellar Electrokinetic Chromatography." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/75048230837880924849.

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碩士<br>國立交通大學<br>應用化學研究所<br>86<br>The purpose of this study was to develop a rapid, high efficiency and high accuracy method applied to the analysis of benzimimdazole fungicides (Benomyl, Carbendazim, Fuberidazole, Thiabendazole and Th-iophanate-methyl ) by micellar electrokinetic chromatography (MEKC).In the analysis benzimidazole fun-gicides, we used pH=7.91 16mM phosphate buffer containing 50mM SDS as separation media. The benz-imidazole fungicides were completely separated within 7minutes. Sample pretreatment was performed by supercritical fluid extraction (SFE).Recoveries ranging from 74
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45

Lai, Mei-yi, and 賴玫儀. "Benzimidazole-Based Electron-transporting Materials for Electroluminescent Device." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/50617214927555758573.

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碩士<br>國立中央大學<br>化學研究所<br>95<br>In this study, we have sucessfully synthesized a series of compound containing benzimidazole and/or arylamine moieties. These compounds emit from purple- blue to orange-red. These compounds are amorphous with glass transition temperatures ranging from 104 to 170 oC and high thermal decomposition temperature (Td > 340 oC) . Among them, EF-I-N, EF-I-N2, SPY-I-N exhibited both good electron- and hole-transporting (mobilities ~10-5 cm2/(V·s)) and emitting abilities. The single-layer devices (ITO/cpd/LiF/Al) of them showed good performance( ext 3.5%; 1.8 lm/W; 3.6 cd/
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46

Chang, Wei-Chia, and 張惟嘉. "Development of Benzimidazole-containing Dibenzofurans for Phosphorescent OLED." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/04088462043346343168.

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碩士<br>國立高雄大學<br>應用化學系碩士班<br>103<br>High efficiency and low driving voltage of Phosphorescent organic light-emitting diodes (PhOLEDs) has been a goal in flat-panel displays and lighting sources nowadays. The performance of the PhOLEDs can be improved substantially by doping phosphorescent dye into the bipolar host. In this work, three novel bipolar host materials (DBFIm28, DBFIm46 and DBFPhIm46) comprising of a hole-transport dibenzofuran core functionalized with electron-transport moieties (N-phenylbenzimidazole) have been synthesized. In order to assess the potential of bipolar molecules for
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Chang, Kai-Wei, and 張凱惟. "Design and Synthesis of Benzimidazole Derivativesas Potential AnticancerAgents." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/57432237190751733563.

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碩士<br>中國醫藥大學<br>藥物化學研究所碩士班<br>97<br>Microtubules are valids target for anticancer drugs, and it is necessary to continue developing those antimitotic drugs as chemotherapeutic agents. Mcrotubulin inhibitors can be divided two classes：(1) MT depolymerization inhibitors; (2) MT polymerization inhibitors. CA-4 is one of the most potent antitubulin agents binding to the colchicine-binding site and inducing morphological changes in the endoethelial cells of the tumor’s blood vessel so as to irreversibly shut down the blood flow to neoplastic cells. Because of its poor solubility in water, a more so
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Chen, Yi-Chia, and 陳憶加. "Synthesis and Characterization of Bis(indole-N-benzimidazole) and Bis(carbazole-N-benzimidazole) and The Applications in Organic Light Emitting Diodes." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/94289563460682358018.

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碩士<br>國立臺灣大學<br>化學研究所<br>105<br>In this thesis, we synthesized two series of compounds― bis(indole-N-benzimidazole) and bis(carbazole-N-benzimidazole) as the host materials in OLED. In this bipolar system, carbazole and indole groups which have high triplet energy and good hole-transporting ability as the hole-transporting moiety, and benzimidazole as the electron-transporting moiety. Directly connect two moieties and compare the effect of different substituted position. In addition, we increase molecular weights to improve their thermal stability. We have been performed Ultraviolete-visible (
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洪懿慈. "Discovery of Novel RAD 51 and NF-kB Inhibitors : IBR2 Analogues and Aminofuran fused Benzimidazole and Synthesis of Phosphonyl Pyrazole fused Benzimidazole." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/9dfyeg.

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碩士<br>國立交通大學<br>應用化學系碩博士班<br>100<br>In this thesis, we used multicomponent reactions for synthesis of different main architecture of small organic molecules and did the biological screening for anticancer activity, in order to identify the high inhibition of drug leads. This thesis can be divided into three parts: The first part reported the improvement of the synthetic approach for the assembling of IBR2 analogues. The original two steps synthetic route was improved to one pot tandem reaction and the reaction time was reduced to 30 minutes from 20 hours. Based on this efficient synthetic appr
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黃瑞祥. "Synthesis, Structures and Properties of Benzimidazole-Containing Metal Complexes." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/26012052132633018472.

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碩士<br>國立彰化師範大學<br>化學系<br>97<br>In this thesis, four types of ligands, 2-(4´-carboxyphenyl)-3H-benzimidale-5-car boxylic acid (H2L1), 2,2´-bis[2-(1-hydrobenzimidazol-2-yl)]biphenyl (L2), 1-(4-((1H-benzi -midazol-1-yl)methyl)-2,5-diisopropylbenzyl)-1H-benzimidazole (L3), 1-(5-((1H-benzimi -dazol-1-yl)methyl)-2,4-diisopropylbenzyl)-1H-benzimidazole (L4) were reacted with Co2+、Cu2+、Cd2+ or Mn2+ metal ion, respectively. In addition, the rhenium-bpt complex [Re(bpt)(CO)3(H2O)] (1) was synthesized by a one-pot reaction. In the hydrothermal process, the 3,5-bis(2-pyridyl)-1,2,4-triazolate was produce
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