Academic literature on the topic 'Benzo[b]tiophen-3-ol derivatives'

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Journal articles on the topic "Benzo[b]tiophen-3-ol derivatives"

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Guglielmi, Paolo, Daniela Secci, Anél Petzer, et al. "Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity." Journal of Enzyme Inhibition and Medicinal Chemistry 34, no. 1 (2019): 1511–25. http://dx.doi.org/10.1080/14756366.2019.1653864.

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Katzsch, Felix, Tobias Gruber, and Edwin Weber. "Crystal structures of functional building blocks derived from bis(benzo[b]thiophen-2-yl)methane." Acta Crystallographica Section C Structural Chemistry 72, no. 9 (2016): 679–84. http://dx.doi.org/10.1107/s2053229616012973.

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The syntheses of three bis(benzo[b]thiophen-2-yl)methane derivatives, namely bis(benzo[b]thiophen-2-yl)methanone, C17H10OS2, (I), 1,1-bis(benzo[b]thiophen-2-yl)-3-(trimethylsilyl)prop-2-yn-1-ol, C22H20OS2Si, (II), and 1,1-bis(benzo[b]thiophen-2-yl)prop-2-yn-1-ol, C19H12OS2, (III), are described and their crystal structures discussed comparatively. The conformation of ketone (I) and the respective analogues are rather similar for most of the compounds compared. This is true for the interplanar angles, the Caryl—Cbridge—Carylangles and the dihedral angles. The best resemblance is found for a bio
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Bremner, JB, and KN Winzenberg. "Photosolvolysis of Bridgehead Quaternary Ammonium Salts. III. Synthesis of Some 3-Benzazecine, 1H-2,6-Benzoxazecine and 2H-3,6-Benzoxazecine Derivatives and a 2H-1,4-Oxazocine Derivative." Australian Journal of Chemistry 38, no. 11 (1985): 1591. http://dx.doi.org/10.1071/ch9851591.

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Photosolvolysis of a mixture of cis - and trans-9,10-dimethoxy-5-methyl- 1,3,4,6,7,11b-hexahydro-2H-benzo[a] quinolizinium iodide (2) in methanol gave, after workup, a very low yield of 8,10,11-trimethoxy-3-methyl- 1,2,3,4,5,6,7,8-octahydro-3-benzazecine (3a). Similarly 1,10,11 trimethoxy-6-methyl-3,4,5,6,7,8-hexahydro-1H-2,6-benzoxazecine (8a) and 1,10,11-trimethoxy-6-methyl-1,4,5,6,7,8-hexahydro-2H-3,6-benzoxazecine (16a) were obtained in fair and low yields respectively from the N- methyl tetrahydro-2H,6H-[1,3] oxazino [2,3-a] isoquinolinium (7a) and hexahydro [1,4] oxazino [3,4-a] isoquino
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Gour, Pankaj, Lata Deshmukh, Tulshiram Dadmal, and Archana Ramteke. "Synthesis and Antimicrobial Activity of 1,2,3-Triazole Linked Benzo[d]oxazole-2-thiol/ oxazolo[4,5-b]pyridine-2-thiol Derivatives." Asian Journal of Organic & Medicinal Chemistry 6, no. 1 (2021): 7–12. http://dx.doi.org/10.14233/ajomc.2021.ajomc-p293.

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A new series of 1,2,3-triazole linked mercaptobenzoxazole/oxazolo- [4,5-b] pyridine-2-thiol derivatives (6a-j) were synthesized starting from 2-aminophenol/2-aminopyridin-3-ol in three steps via cyclization, alkylation followed by reaction with various aromatic azides using click chemistry approach. All the synthesized compounds were evaluated for their antimicrobial activity viz. E. coli, P. aeruginosa, S. aureus and S. pyogenus and three pathogenic fungi viz. C. albicans, A. niger and A. clavatus and promising compounds were identified.
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Chan, Wai N., John M. Evans, Michael S. Hadley, et al. "Synthesis of Noveltrans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile†." Journal of Medicinal Chemistry 39, no. 23 (1996): 4537–39. http://dx.doi.org/10.1021/jm960535w.

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Babu, C. Naresh, S. Triveni, M. Vijaya Jyothi, B. Yamuna, and A. Yamini. "Design, Synthesis and Antimicrobial Evaluation of Novel 2-Thiobenzimidazole Derivatives: in silico and in vitro Approach." Asian Journal of Chemistry 32, no. 11 (2020): 2753–62. http://dx.doi.org/10.14233/ajchem.2020.22821.

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The development of potent antimicrobial agents is more essential due to resistance developed in microorganisms towards the existing drugs. The diversity in the biological retort profile of benzimidazole more attracted the attention to develop novel compounds to its various potential against microorganisms. In present work, designed molecular structures docked against DNA gyrase subunit B and lanosterol 14α-demethylase (LAD) proteins. Interestingly, most of the compounds revealed excellent docking scores and interactions compared with the co-crystal ligands KKK, 1YN of LAD proteins 3LD6, 5V5Z t
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CHAN, W. N., J. M. EVANS, M. S. HADLEY, et al. "ChemInform Abstract: Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H- benzo(b)pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile." ChemInform 28, no. 8 (2010): no. http://dx.doi.org/10.1002/chin.199708134.

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Krogh, Erik, and Peter Wan. "Photosolvolysis of 11H-benzo[b]fluoren-11-ol in aqueous solution." Canadian Journal of Chemistry 68, no. 10 (1990): 1725–31. http://dx.doi.org/10.1139/v90-268.

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The photosolvolysis of 11H-benzo[b]fluoren-11-ol (2), a 9-fluorenol derivative, has been studied in aqueous solution to test the hypothesis of enhanced photosolvolytic reactivity of these compounds. It is found that compared to the model compound, α-phenyl-2-naphthalenemethanol (3), 2 exhibited enhanced photosolvolytic reactivity. Quantum yields for photosolvolysis in aqueous alcohol solutions and steady-state and transient fluorescence studies are reported in neutral and acid solutions. The results further support the notion that an intrinsically accelerated photodehydroxylation step is assoc
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Andrews, Fleur L., David S. Larsen, and Lesley Larsen. "Synthetic Approaches to the Angucycline Antibiotics. A Route to C-Glycosidic Benz[a]anthraquinones." Australian Journal of Chemistry 53, no. 1 (2000): 15. http://dx.doi.org/10.1071/ch99124.

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3-Deoxy-6′-hydroxy-13-norurdamycinone B (32a) and 3-deoxy-13-norurdamycinone B (32b) have been synthesized in eight steps from 5,8-dimethoxynaphthalen-1-ol (9) both in 28% overall yield. The key step in this approach is the boron trifluoride diethyl etherate promoted β-C-glycosylations of (9) and 1,3,4,6-tetra-O-acetyl-2-deoxy- and 1,3,4-tri-O-acetyl-2-deoxy-D-arabino-hexopyranoses (13) and (19). The solvent, acetonitrile, was essential for the success of these reactions. Acetylation of the C-glycosyl-5,8-dimethoxynaphthalen-1-ols (16) and (20) followed by oxidation with ceric ammonium nitrate
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Janin, Yves L., Glwadys Gagnot, Pierre Legrand, Amira Tadros, Fatima Ezzahra Hibti, and Alessia Quatela. "On Pyridopyrazinol Chemistry: Synthesis of Chemiluminescent Substances." Synthesis, February 22, 2021. http://dx.doi.org/10.1055/a-1396-8607.

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AbstractOur work on new chemiluminescent substances related to the marine luciferin coelenterazine (λmax = 465 nm) led us to attempt the synthesis of four nitrogen-rich pyridopyrazine-bearing analogues. Accordingly, the preparation of the corresponding benzyl-bearing pyridopyrazinols is studied. By varying the conditions for the condensation of phenylpyruvic acid with 1,2-diaminopyridine or 3,4-diaminopyridine, all the possible pyridopyrazin-2-ol regioisomers are isolated and properly characterized, including by means of crystallographic studies. The ensuing syntheses of the halogenated pyrido
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Dissertations / Theses on the topic "Benzo[b]tiophen-3-ol derivatives"

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GUGLIELMI, PAOLO. "Synthesis and biological evaluation of new saccharin-based inhibitors of cancer-related carbonic anhydrase IX and XII isoforms & Benzo[b]tiophen-3-ol derivatives as effective inhibitors of hMAOs: design, synthesis and biological activity." Doctoral thesis, 2018. http://hdl.handle.net/11573/1213367.

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Synthesis and biological evaluation of new saccharin-based inhibitors of cancer-related carbonic anhydrase IX and XII isoforms Carbonic anhydrases (CAs, EC 4.2.1.1) are widespread metalloenzymes implicated in many cellular and physiological processes requiring bicarbonate as substrate (e.g. electrolyte secretion, pH homoeostasis, respiration etc.). The fifteen human isoforms of carbonic anhydrase (hCAs) differ in cellular localization (cytosol, mitochondria or cell membrane), sensibility to inhibitors and catalytic activity. hCAs are well established therapeutic targets to treat a wide rang
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