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Journal articles on the topic 'Benzodioxane'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Aitmambetov, A., G. Berdimbetova, and V. P. Khilya. "Synthetic analogs of natural flavolignans VIII. Synthesis of 6-chloro-1,3-benzodioxane, 1,4-benzodioxane, 1,5-benzodioxepane, and 1,6-benzodioxocane analogs of 4-thioflavone." Chemistry of Natural Compounds 33, no. 3 (May 1997): 286–88. http://dx.doi.org/10.1007/bf02234875.

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2

Corsano, Stefano, Giovannella Strappaghetti, and Antonella Codagnone. "Synthesis and Antihypertensive Properties of Benzodioxane-pyridazinones and Benzodioxane-dihydropyridazinones Synthese und antihypertensive Eigenschaften von Benzodioxan-pyridazinonen und Benzodioxan-dihydropyridazinonen." Archiv der Pharmazie 322, no. 11 (1989): 833–35. http://dx.doi.org/10.1002/ardp.19893221113.

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3

Sokolovskii, A. V., Yu B. Zelechonok, V. V. Zorin, S. S. Zlotskii, and D. L. Rakhmankulov. "Homolytic alkylation of 2-methylquinoline by benzodioxolane and benzodioxane." Chemistry of Heterocyclic Compounds 22, no. 4 (April 1986): 467–68. http://dx.doi.org/10.1007/bf00542797.

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4

Varadaraju, Kavitha Raj, Jajur Ramanna Kumar, Lingappa Mallesha, Archana Muruli, Kikkeri Narasimha Shetty Mohana, Chethan Kumar Mukunda, and Umesha Sharanaiah. "Virtual Screening and Biological Evaluation of Piperazine Derivatives as Human Acetylcholinesterase Inhibitors." International Journal of Alzheimer's Disease 2013 (2013): 1–13. http://dx.doi.org/10.1155/2013/653962.

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The piperazine derivatives have been shown to inhibit human acetylcholinesterase. Virtual screening by molecular docking of piperazine derivatives 1-(1,4-benzodioxane-2-carbonyl) piperazine (K), 4-(4-methyl)-benzenesulfonyl-1-(1,4-benzodioxane-2-carbonyl) piperazine (S1), and 4-(4-chloro)-benzenesulfonyl-1-(1,4-benzodioxane-2-carbonyl) piperazine (S3) has been shown to bind at peripheral anionic site and catalytic sites, whereas 4-benzenesulfonyl-1-(1,4-benzodioxane-2-carbonyl) piperazine (S4) and 4-(2,5-dichloro)-benzenesulfonyl-1-(1,4-benzodioxane-2-carbonyl) piperazine (S7) do not bind either to peripheral anionic site or catalytic site with hydrogen bond. All the derivatives have differed in number of H-bonds and hydrophobic interactions. The peripheral anionic site interacting molecules have proven to be potential therapeutics in inhibiting amyloid peptides aggregation in Alzheimer’s disease. All the piperazine derivatives follow Lipinski’s rule of five. Among all the derivatives 1-(1,4-benzodioxane-2-carbonyl) piperazine (K) was found to have the lowest TPSA value.

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5

Daukshas, V. K., P. G. Gaidyalis, A. B. Brukshtus, Yu Yu Ramanauskas, L. K. Labanauskas, G. A. Gasperavichene, I. Yu Yautakene, V. V. Lapinskas, and N. A. Lauzhikene. "Synthesis and pharmacological activity of 1,3-benzodioxolane and 1,3-benzodioxane derivatives." Pharmaceutical Chemistry Journal 23, no. 8 (August 1989): 660–64. http://dx.doi.org/10.1007/bf00766383.

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6

Mori, Sachio, and Shozo Takechi. "Synthesis of Benzodioxane Prostacyclin Analogue." HETEROCYCLES 31, no. 7 (1990): 1189. http://dx.doi.org/10.3987/com-90-5370.

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7

Hirata, Makoto, and Eiji Taniguchi. "Synthesis of (+)-(2S, 3S)-Benzodioxane." Journal of the Faculty of Agriculture, Kyushu University 42, no. 1/2 (December 1997): 101–12. http://dx.doi.org/10.5109/24197.

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8

Aitmambetov, A., and V. P. Khilya. "Synthetic and modified isoflavonoids. IX. Synthesis of benzodioxolane and benzodioxane analogs of 3-arylcoumarins." Chemistry of Natural Compounds 30, no. 2 (March 1994): 211–13. http://dx.doi.org/10.1007/bf00630008.

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9

Jeyamogan, Shareni, Naveed Ahmed Khan, Ayaz Anwar, Muhammad Raza Shah, and Ruqaiyyah Siddiqui. "Cytotoxic effects of Benzodioxane, Naphthalene diimide, Porphyrin and Acetamol derivatives on HeLa cells." SAGE Open Medicine 6 (January 1, 2018): 205031211878196. http://dx.doi.org/10.1177/2050312118781962.

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Objectives: To synthesize novel compounds belonging to Benzodioxane, Naphthalene diimide, Aminophenol derivatives and Porphyrin classes and test their potential anticancer properties. Methods: Several compounds were synthesized and their molecular identity was confirmed using nuclear magnetic resonance. Potential anticancer properties were determined using cytopathogenicity assays and growth inhibition assays using cervical cancer cells (HeLa). Cells were incubated with different concentrations of compounds belonging to Benzodioxane, Naphthalene diimide, Aminophenol derivatives and Porphyrins and effects were determined. HeLa cells cytopathogenicity was determined by measuring lactate dehydrogenase release using cytotoxicity detection assay. Growth inhibition assays were performed by incubating 50% semi-confluent HeLa cells with Benzodioxane, Naphthalene diimide, Aminophenol derivatives and Porphyrin compounds and HeLa cell proliferation was observed. Growth inhibition and host cell death were compared in the presence and absence of drugs. Results: Cytopathogenicity assays showed that the selected compounds were cytotoxic against HeLa cells, killing up to 90% of cells. Growth inhibition assays exhibited 100% growth inhibition. These effects are likely via oxidative stress, production of reactive oxygen species, changes in cytosolic and intracellular calcium/adenine nucleotide homeostasis, inhibition of ribonucleotide reductase/cyclooxygenase and/or glutathione depletion. Conclusions: Benzodioxane, Naphthalene diimide, Aminophenol derivatives and Porphyrins exhibited potent anticancer properties. These findings are promising and should pave the way in the rationale development of anticancer drugs. Using different cancer cell lines, future studies will determine their potential as anti-tumour agents as well as their precise molecular mode of action.

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10

Ferenczi, Renáta Kertiné, Tünde-Zita Illyés, Sándor Balázs Király, Gyula Hoffka, László Szilágyi, Attila Mándi, Sándor Antus, and Tibor Kurtán. "Evaluation of Different Synthetic Routes to (2R,3R)-3-Hydroxymethyl-2-(4-hydroxy- 3-methoxyphenyl)-1,4-Benzodioxane-6-Carbaldehyde." Current Organic Chemistry 23, no. 26 (January 1, 2020): 2960–68. http://dx.doi.org/10.2174/1385272823666191212113407.

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The reported enantioselective synthesis for the preparation of (+)-(2R,3R)-2-(4- hydroxy-3-methoxyphenyl)-3-hydroxymethyl-1,4-benzodioxane-6-carbaldehyde, precursor for the stereoselective synthesis of bioactive flavanolignans, could not be reproduced. Thus, the target molecule was prepared via the synthesis and separation of diastereomeric O-glucosides. TDDFT-ECD calculations and the 1,4-benzodioxane helicity rule were utilized to determine the absolute configuration. ECD calculations also confirmed that the 1Lb Cotton effect is governed by the helicity of the heteroring, while the higher-energy ECD transitions reflect mainly the orientation of the equatorial C-2 aryl group.

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11

Vidal, B., JY Conan, G. Lamaty, and J. Vardin. "Geometry of Some Strained Oxygen Ring Compounds: 1,3-Benzodioxole and 2,3-Dihydro-1,4-benzodioxin (Benzodioxan). Application to the Geometry of (6aR-cis)-3-Methoxy-6a,12a-dihydro-6h-[1,3]dioxolo-[5,6]benzofuro[3,2-C] [1]benzopyran (Pterocarpin)." Australian Journal of Chemistry 41, no. 7 (1988): 1107. http://dx.doi.org/10.1071/ch9881107.

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The geometry of benzodioxole, benzodioxan and the strained five- membered rings of pterocarpin are studied by the MNDO method. We show that in benzodioxole there is bond alternation towards a Kekule -like structure such as in indan (Mills-Nixon effect). In benzodioxole, owing to the smaller perimeter of the fused ring and enhanced strain, alternation is more pronounced than in indan . An explanation is offered for the strong distortion in ring angles in benzodioxole compared with indan. The effect of strain in benzodioxan and pterocarpin is discussed.

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12

Srivastava, Shaifali, Madan M. Gupta, Ram K. Verma, and Sushil Kumar. "Determination of 1,3-Benzodioxanes in Piper mullesua by High-Performance Thin-Layer Chromatography." Journal of AOAC INTERNATIONAL 83, no. 6 (November 1, 2000): 1484–88. http://dx.doi.org/10.1093/jaoac/83.6.1484.

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Abstract A new, simple, precise, and rapid high-performance thin-layer chromatographic method was developed for the determination of 6 benzodioxanes in Piper mullesua extract: 1′,3′-benzodioxole-5′-(2,4,8-triene-isobutyl nonanoate), 1′,3′-benzodioxole-5′-(2,4,12-triene-isobutyl tridecanoate), fargesin, sesamin, asarinin, 1′,3′-benzodioxole-5′-(2,4,8-triene-methyl nonanoate). The ingredients were separated on a precoated Silica Gel 60 F254 plate with a solvent system of toluene–acetone (92 + 8). The 6 benzodioxanes were well separated and easily identified in this chromatographic system. The separated benzodioxanes were visualized by color development with a spray reagent consisting of 1 g vanillin dissolved in 100 mL H2SO4–ethanol (5 + 95, v/v). Quantitation was performed by scanning the spots and comparing the integrated areas of compounds in samples with those of standards. Recoveries from samples spiked with known amounts of the benzodioxanes were excellent. The results were comparable with those estimated by liquid chromatography.

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13

Bolchi, Cristiano, Ermanno Valoti, Valentina Straniero, Paola Ruggeri, and Marco Pallavicini. "From 2-Aminomethyl-1,4-benzodioxane Enantiomers to Unichiral 2-Cyano- and 2-Carbonyl-Substituted Benzodioxanes via Dichloroamine." Journal of Organic Chemistry 79, no. 14 (June 26, 2014): 6732–37. http://dx.doi.org/10.1021/jo500964y.

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14

ISHIBASHI, Fumito, and Eiji TANIGUCHI. "Synthesis of the benzodioxane portion of haedoxans." Agricultural and Biological Chemistry 53, no. 6 (1989): 1557–63. http://dx.doi.org/10.1271/bbb1961.53.1557.

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15

MORI, S., and S. TAKECHI. "ChemInform Abstract: Synthesis of Benzodioxane Prostacyclin Analogue." ChemInform 22, no. 2 (August 23, 2010): no. http://dx.doi.org/10.1002/chin.199102224.

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16

Ishibashi, Fumito, and Eiji Taniguchi. "Synthesis of the Benzodioxane Portion of Haedoxans." Agricultural and Biological Chemistry 53, no. 6 (June 1989): 1557–63. http://dx.doi.org/10.1080/00021369.1989.10869498.

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17

Li, Yanding, Li Shuai, Hoon Kim, Ali Hussain Motagamwala, Justin K. Mobley, Fengxia Yue, Yuki Tobimatsu, et al. "An “ideal lignin” facilitates full biomass utilization." Science Advances 4, no. 9 (September 2018): eaau2968. http://dx.doi.org/10.1126/sciadv.aau2968.

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Lignin, a major component of lignocellulosic biomass, is crucial to plant growth and development but is a major impediment to efficient biomass utilization in various processes. Valorizing lignin is increasingly realized as being essential. However, rapid condensation of lignin during acidic extraction leads to the formation of recalcitrant condensed units that, along with similar units and structural heterogeneity in native lignin, drastically limits product yield and selectivity. Catechyl lignin (C-lignin), which is essentially a benzodioxane homopolymer without condensed units, might represent an ideal lignin for valorization, as it circumvents these issues. We discovered that C-lignin is highly acid-resistant. Hydrogenolysis of C-lignin resulted in the cleavage of all benzodioxane structures to produce catechyl-type monomers in near-quantitative yield with a selectivity of 90% to a single monomer.

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18

Pilkington, Lisa I., and David Barker. "Synthesis and biology of 1,4-benzodioxane lignan natural products." Natural Product Reports 32, no. 10 (2015): 1369–88. http://dx.doi.org/10.1039/c5np00048c.

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This review describes the evolution of synthetic methods towards 1,4-benzodioxane lignan natural products, from early biomimetic approaches to recent enantiospecific syntheses. Additionally, a comprehensive report of their biosynthesis and significant biological activities is detailed.

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19

Gu, Wenxin, Xiaobi Jing, Xinfu Pan, Albert S. C. Chan, and Teng-Kuei Yang. "First asymmetric synthesis of chiral 1,4-benzodioxane lignans." Tetrahedron Letters 41, no. 32 (August 2000): 6079–82. http://dx.doi.org/10.1016/s0040-4039(00)00820-0.

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20

Chiodini, Giuseppe, Marco Pallavicini, Carlo Zanotto, Massimiliano Bissa, Antonia Radaelli, Valentina Straniero, Cristiano Bolchi, et al. "Benzodioxane–benzamides as new bacterial cell division inhibitors." European Journal of Medicinal Chemistry 89 (January 2015): 252–65. http://dx.doi.org/10.1016/j.ejmech.2014.09.100.

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21

Aitmambetov, A., Z. Yu Ibragimova, and A. Tokhtybaeva. "Synthetic analogs of natural flavolignans. XII. Synthesis of 3,5-diarylsubstituted pyrazolines based on 1,3-benzodioxane and 1,4-benzodioxane chalcone analogs." Chemistry of Natural Compounds 40, no. 6 (November 2004): 541–43. http://dx.doi.org/10.1007/s10600-005-0031-0.

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22

Antus, Sándor, Agnes Gottsegen, Judit Kajtár, Tibor Kovács, Tante S. Tóth, and Hildebert Wagner. "Lipase-catalyzed kinetic resolution of (±)-2-hydroxymethyl-1,4-benzodioxane." Tetrahedron: Asymmetry 4, no. 3 (March 1993): 339–44. http://dx.doi.org/10.1016/s0957-4166(00)86078-4.

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23

Avakyan, A. S., S. O. Vartanyan, A. B. Sargsyan, and E. A. Markaryan. "Synthesis of new biheterocycles containing a 1,4-benzodioxane fragment." Russian Journal of Organic Chemistry 50, no. 3 (March 2014): 434–38. http://dx.doi.org/10.1134/s1070428014030233.

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24

Jing, Xiao-Bi, Li Wang, Ying Han, Yao-Cheng Shi, Yong-Hong Liu, and Jing Sun. "Total Synthesis of Six Natural Products of Benzodioxane Neolignans." Journal of the Chinese Chemical Society 51, no. 5A (October 2004): 1001–4. http://dx.doi.org/10.1002/jccs.200400149.

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25

Tlegenov, R. T. "Synthesis of 8-benzodioxane azomethines of the alkaloid lupinin." Chemistry of Natural Compounds 43, no. 4 (July 2007): 499–500. http://dx.doi.org/10.1007/s10600-007-0176-0.

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26

Massacret, Magali, Catherine Goux, Paul Lhoste, and Denis Sinou. "One-pot preparation of chiral 2-vinyl-1,4-benzodioxane." Tetrahedron Letters 35, no. 33 (August 1994): 6093–96. http://dx.doi.org/10.1016/0040-4039(94)88084-0.

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27

Siddiqui, Ruqaiyyah, Ayaz Anwar, Salwa Ali, and Naveed Ahmed Khan. "Antibacterial Effects of Derivatives of Porphyrin, Naphthalene diimide, Aminophenol and Benzodioxane on Methicillin Resistant Staphylococcus aureus and Neuropathogenic Escherichia coli K1." Anti-Infective Agents 18, no. 3 (September 11, 2020): 275–84. http://dx.doi.org/10.2174/2211352517666190628111232.

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Background: Infectious diseases contribute to substantial mortality and morbidity worldwide despite advances in therapeutic intervention highlighting the need to identify drugs with antimicrobial properties. Methods: Here, we utilised several compounds from the following classes: porphyrin, naphthalene diimide, aminophenol derivatives, and benzodioxane, and evaluated their antibacterial activities. Bactericidal and bacteriostatic activity of these compounds were determined against methicillinresistant Staphylococcus aureus (MRSA) and Escherichia coli K1 with various concentrations of the drugs. Moreover, the ability of the bacteria to bind/associate to host cells was also ascertained in the absence and presence of aforementioned compounds. Results: The results revealed that porphyrin derivative (AYTHPP) had potent effects against MRSA, abolishing viability and blocking binding to the host cells. Importantly, novel AYTHPP exhibited powerful effects against MRSA even though it was not photoactivated. In contrast, other compounds, including naphthalene diimide, acetamol derivatives and benzodioxane, showed no inhibitory effects. Conclusion: The mechanism of action of porphyrin is likely through the production of reactive oxygen species causing oxidative stress, leading to apoptosis and/or necrosis via perturbations in the plasma membrane. Future studies will determine their in vivo efficacy together will associated molecular mode of action.

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28

Melchiorre, C., P. Angeli, M. L. Bolognesi, A. Chiarini, D. Giardinà, U. Gulini, A. Leonardi, et al. "α1-Adrenoreceptor antagonists bearing a quinazoline or a benzodioxane moiety." Pharmaceutica Acta Helvetiae 74, no. 2-3 (March 2000): 181–90. http://dx.doi.org/10.1016/s0031-6865(99)00049-7.

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29

Bolchi, Cristiano, Marco Pallavicini, Laura Fumagalli, Paola Ruggeri, and Ermanno Valoti. "Diastereomeric 2-aminomethyl-1,4-benzodioxane mandelates: phase diagrams and resolution." Tetrahedron: Asymmetry 24, no. 13-14 (July 2013): 796–800. http://dx.doi.org/10.1016/j.tetasy.2013.05.010.

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30

Gotanda, Hiroshi, Satoshi Yamauchi, Fumito Ishibashi, and Eiji Taniguchi. "Chromano-analogs of Insecticidal Neolignans of the 1,4-Benzodioxane Type." Bioscience, Biotechnology, and Biochemistry 57, no. 6 (January 1993): 884–89. http://dx.doi.org/10.1271/bbb.57.884.

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31

Gu, Wenxin, Xiaobi Jing, Xinfu Pan, Albert S. C. Chan, and Teng-Kuei Yang. "ChemInform Abstract: First Asymmetric Synthesis of Chiral 1,4-Benzodioxane Lignans." ChemInform 31, no. 44 (October 31, 2000): no. http://dx.doi.org/10.1002/chin.200044158.

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32

da Silva, Marcelo S., José M. Barbosa-Filho, Massayoshi Yoshida, and Otto R. Gottlieb. "Benzodioxane and β-aryloxy-arylpropane type neolignans from Licaria chrysophylla." Phytochemistry 28, no. 12 (January 1989): 3477–82. http://dx.doi.org/10.1016/0031-9422(89)80368-1.

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33

Li, K., and R. F. Helm. "Neolignan Skeletons and Benzodioxanes Through Chiral Aryl Alkyl Ether Formation." Holzforschung 54, no. 6 (October 25, 2000): 597–603. http://dx.doi.org/10.1515/hf.2000.101.

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Summary Several chiral neolignan skeletons and a benzodioxane were prepared from a tartrate derivative with the crucial chiral aryl alkyl ether formation being accomplished with cesium phenolate and 18-crown-6. These compounds have greater than 96% enantiomeric excess, and this work represents the first successful synthetic preparation of optically active 8-O-4′ type neolignan skeletons. The chiral aryl alkyl ethers were also synthesized from several protected carbohydrates, which can serve as chiral auxiliaries for a wide variety of target molecules.

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34

Bhat, Mashooq Ahmad, Mohamed A. Al-Omar, Azmat Ali Khan, Amer M. Alanazi, and Ahmed M. Naglah. "Synthesis and antihepatotoxic activity of dihydropyrimidinone derivatives linked with 1,4-benzodioxane." Drug Design, Development and Therapy Volume 13 (July 2019): 2393–404. http://dx.doi.org/10.2147/dddt.s198865.

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35

Chhakra, Sandhya, A. Mukherjee, H. L. Singh, and Suresh Singh Chauhan. "Synthesis of Novel Substituted 1,5-Benzothiazepines Containing 1,4-Benzodioxane Sulfonyl Moiety." Asian Journal of Organic & Medicinal Chemistry 4, no. 2 (2019): 70–76. http://dx.doi.org/10.14233/ajomc.2019.ajomc-p159.

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An efficient synthesis of novel 2,3,4-trisubstituted 1,5-benzothiazepines (4a-e) incorporating the sulfonyl group is described. Compound (4a-e) was synthesized by the reaction of 3-(1,4-dioxane-6-sulfonyl)-2,4-dimethyl/4-methyl-2-phenyl/2,4-diphenyl/2-ethoxy-4-methyl/2,4-diethoxy propane-1,3-dione (3ae) with 2-aminobenzenethiol with ZnOnanoparticles/pyridine. Formation of compound (3a-e) was achieved by the reaction of 1,4-dioxane-6-sulfonyl chloride (1) with 2,4-dimethyl/4-methyl-2-phenyl/2,4-diphenyl/2-ethoxy-4-methyl/2,4-diethoxy propane-1,3-dione (2a-e). The benzothiazepines (4a-e) obtained were purified by column chromatography (benzene: CHCl3, 40:60, 30:70, 20:80, 10:90) and crystallized from methanol. The purity of the compounds was checked by TLC using (CHCl3: CH3OH, 9:1) as the mobile phase. The structure of the compounds has been established by elemental, IR, 1H NMR, 13C NMR and Mass spectral analyses. Frontier molecular orbitals of the title compounds have been studied in the ground state speculatively. The reactivity of a molecule using diverse descriptors such as softness, electrophilicity, electronegativity, HOMO-LUMO energy gap is calculated additionally discussed.

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36

ANTUS, S., A. GOTTSEGEN, J. KAJTAR, T. KOVACS, T. S. TOTH, and H. WAGNER. "ChemInform Abstract: Lipase-Catalyzed Kinetic Resolution of (.+-.)-2-Hydroxymethyl-1,4- benzodioxane." ChemInform 24, no. 28 (August 20, 2010): no. http://dx.doi.org/10.1002/chin.199328084.

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37

MASSACRET, M., C. GOUX, P. LHOSTE, and D. SINOU. "ChemInform Abstract: One-Pot Preparation of Chiral 2-Vinyl-1,4-benzodioxane." ChemInform 26, no. 1 (August 18, 2010): no. http://dx.doi.org/10.1002/chin.199501168.

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38

Varró, Gábor, Balázs Pogrányi, Alajos Grün, András Simon, László Hegedűs, and István Kádas. "Stereoselective synthesis of trans-dihydronarciclasine derivatives containing a 1,4-benzodioxane moiety." Monatshefte für Chemie - Chemical Monthly 149, no. 12 (October 26, 2018): 2265–85. http://dx.doi.org/10.1007/s00706-018-2287-7.

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39

Aitmambetov, A., L. G. Grishko, and V. P. Khilya. "Synthetic and modified isoflavonoids III. Synthesis of benzodioxane analogues of pseudobaptigenin." Chemistry of Natural Compounds 29, no. 6 (November 1993): 720–25. http://dx.doi.org/10.1007/bf00629638.

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40

Begum, Shaheen, M. S. Rashida Anjum, G. Poojitha Harisree, N. Sivalakshmi, P. Priyanka, and K. Bharathi. "Antioxidant Activity of Piperazine Compounds: A Brief Review." Asian Journal of Chemistry 32, no. 9 (2020): 2105–18. http://dx.doi.org/10.14233/ajchem.2020.22832.

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Piperazine ring is found in several potent antioxidant molecules. Literature survey revealed that the piperazine ring has been coupled to different heterocyclic rings such as quinoline, pyridine, pyrazine, azole, 1,3,4-oxadiazole, 1,4-benzodioxane, pyrrolidinone, benzimidazole, pyrazine benzimidazole to obtain compounds with good antioxidant activity. It is found that the natural compounds like α-lipoic acid, methylxanthine, berberine, sarsasapogenin, chrysin, chromen-4-one, co-enzyme Q when attached to piperazine ring, antioxidant activity was improved. In the present article, piperazine containing antioxidant molecules were reviewed.

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41

Khalilullah, Habibullah, Shamshir Khan, Mohamed Jawed Ahsan, and Bahar Ahmed. "Discovery of Novel 1,4-Benzodioxane Containing Thiazolidinone Derivatives as Potential Antihepatotoxic Agent." Bulletin of the Korean Chemical Society 33, no. 2 (February 20, 2012): 575–82. http://dx.doi.org/10.5012/bkcs.2012.33.2.575.

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42

Irshad, Misbah. "Pharmacological Evaluation and Synthesis of New Sulfonamides Derivatives Based on 1,4-Benzodioxane." Pakistan Journal of Analytical & Environmental Chemistry 19, no. 2 (December 28, 2018): 181–94. http://dx.doi.org/10.21743/pjaec/2018.12.20.

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43

Khalilullah, Habibullah, Shamshir Khan, Md Shivli Nomani, and Bahar Ahmed. "Synthesis, characterization and antimicrobial activity of benzodioxane ring containing 1,3,4-oxadiazole derivatives." Arabian Journal of Chemistry 9 (November 2016): S1029—S1035. http://dx.doi.org/10.1016/j.arabjc.2011.11.009.

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44

Vartanyan, S. O., A. B. Sargsyan, A. S. Avakyan, E. A. Markaryan, and T. O. Asatryan. "Synthesis of diamides from 1,4-benzodioxane-2- and isochroman-1-carboxylic acids." Russian Journal of Organic Chemistry 48, no. 7 (July 2012): 972–76. http://dx.doi.org/10.1134/s1070428012070147.

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45

Liu, Jun, De-Xian Wang, Qi-Yu Zheng, and Mei-Xiang Wang. "Biocatalytic Synthesis of Highly Enantiopure 1,4-Benzodioxane-2-carboxylic Acid and Amide." Chinese Journal of Chemistry 24, no. 11 (November 2006): 1665–68. http://dx.doi.org/10.1002/cjoc.200690312.

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Czompa, Andrea, Zoltán Dinya, Sándor Antus, and Zsuzsa Varga. "Synthesis and Antioxidant Activity of Flavanoid Derivatives Containing a 1,4-Benzodioxane Moiety." Archiv der Pharmazie 333, no. 6 (June 2000): 175–80. http://dx.doi.org/10.1002/1521-4184(20006)333:6<175::aid-ardp175>3.0.co;2-c.

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Tlegenov, R. T. "Synthesis and Antituberculosis Activity of 4-aminobenzenesulfamido-2-thiazole 8-benzodioxane Azomethines." Pharmaceutical Chemistry Journal 42, no. 7 (July 2008): 382–83. http://dx.doi.org/10.1007/s11094-008-0135-5.

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Trumbo, David L. "Copolymerization of 6-vinyl-1,4-benzodioxane with methyl methacrylate andn-butyl acrylate." Polymer Bulletin 29, no. 3-4 (September 1992): 303–8. http://dx.doi.org/10.1007/bf00944823.

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Khilya, V. P., A. Aitmambetov, A. V. Turov, A. M. Kornilov, D. Litkei, and T. Patonai. "Chemistry of isoflavone heteroanalogs. 11. Benzodioxane analogs of chalcone, flavone, and isoflavone." Chemistry of Heterocyclic Compounds 22, no. 2 (February 1986): 149–54. http://dx.doi.org/10.1007/bf00519934.

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Chu, Zhi-Bo, Jun Chang, Ying Zhu, and Xun Sun. "Chemical Constituents of Cordyceps cicadae." Natural Product Communications 10, no. 12 (December 2015): 1934578X1501001. http://dx.doi.org/10.1177/1934578x1501001233.

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Abstract:

One new bifuran derivative (1), together with fourteen known compounds, were isolated from Cordyceps cicadae X. Q. Shing. The known compounds included nine nucleosides, uracil (2), uridine (3), 2′-deoxyuridine (4), 2′-deoxyinosine (5), guanosine (6), 2′-deoxyguanosine (7), thymidine (8), adenosine (9), and 2′-deoxyadenosine (10); three amino acids tryptophan (11), phenylalanine (12), and tyrosine (13); and two dopamine analogues N-acetylnoradrenaline (14) and its dimer, trans–2-(3′,4′-dihydroxyphenyl)-3-acetylamino-7-( N-acetyl-2″-amino-ethylene)-1,4-benzodioxane (15). Their structures were decisively elucidated by spectroscopic analysis, including 1D and 2D NMR techniques.

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