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Relevant bibliographies by topics / Benzofuran – Synthesis

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Academic literature on the topic 'Benzofuran – Synthesis'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Benzofuran – Synthesis"

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Pirouz, Maryam, M. Saeed Abaee, Pernille Harris, and Mohammad M. Mojtahedi. "One-pot synthesis of benzofurans via heteroannulation of benzoquinones." Heterocyclic Communications 27, no. 1 (2021): 24–31. http://dx.doi.org/10.1515/hc-2020-0120.

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Abstract Three different reactions were explored leading to the synthesis of various benzofurans. All reactions took place under AcOH catalysis in a one-pot manner. As a result, benzoquinone derivatives underwent heteroannulation with either itself or cyclohexanones to produce furanylidene-benzofuran or benzofuran structures, respectively.

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Chen, Ren Er, Yan Li Wang, Zhi Wei Chen, and Wei Ke Su. "A novel and efficient synthesis of bis(benzofuranyl)methanes and 2-benzofuran-1-nitroalkanes catalyzed by Bi(OTf)." Canadian Journal of Chemistry 86, no. 9 (2008): 875–80. http://dx.doi.org/10.1139/v08-091.

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Bismuth (III) triflate-catalyzed Friedel-Crafts reactions between benzofuran and aldehydes in different solvents were investigated. Bis(benzofuranyl)methanes were obtained with good yields when acetonitrile was used as solvent, while in the case of nitromethane the multi-component reaction products, 2-benzofuran-1-nitroalkanes, were formed under similar conditions. A plausible mechanism is given.Key words: benzofuran, aldehyde, bis(benzofuranyl)methanes, Bi(OTf)3, 2-benzofuran-1-nitroalkane.

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Islam, Md Monarul, Thamina Akther, Yusuke Ikejiri, et al. "Synthesis, structural properties, electrophilic substitution reactions and DFT computational studies of calix[3]benzofurans." RSC Advances 6, no. 56 (2016): 50808–17. http://dx.doi.org/10.1039/c6ra06219a.

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Jung, Youngeun, and Ikyon Kim. "Chemoselective reduction of quinols as an alternative to Sonogashira coupling: synthesis of polysubstituted benzofurans." Organic & Biomolecular Chemistry 14, no. 44 (2016): 10454–72. http://dx.doi.org/10.1039/c6ob01941b.

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Rao, Bodapati V. D., Suryadevara V. Vardhini, Deepti Kolli, Mandava V. B. Rao, and Manojit Pal. "Ultrasound Assisted Synthesis of 2-Substituted Benzofurans via One-Pot and Sequential Method: Their In Vitro Evaluation." Anti-Cancer Agents in Medicinal Chemistry 20, no. 5 (2020): 580–88. http://dx.doi.org/10.2174/1871520620666200128120356.

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Background: The 2-substituted benzofuran framework has attracted enormous attention due to its presence in a range of bioactive compounds and natural products. While various methods for the synthesis of 2- substituted benzofuran derivatives are known, several of them suffer from certain drawbacks. Objective: The main objective of this work was to explore a series of 2-(het)aryl substituted benzofurans derivatives for their cytotoxic properties against cancer cell lines in vitro. Methods: In our efforts, we have developed a one-pot synthesis of this class of compounds via sequential C-C couplin

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Camacho-Dávila, Alejandro, José Espinoza-Hicks, Gerardo Zaragoza-Galán, David Chávez-Flores, Víctor Ramos-Sánchez, and Joaquín Tamariz. "A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol." Synthesis 50, no. 17 (2018): 3493–98. http://dx.doi.org/10.1055/s-0037-1610169.

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An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.

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Tsukazaki, Masao, and Victor Snieckus. "Directed ortho metalation – radical-induced cyclization synthetic connections. A route to highly substituted benzofurans." Canadian Journal of Chemistry 70, no. 5 (1992): 1486–91. http://dx.doi.org/10.1139/v92-184.

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The synthesis of benzofurans 20a–c, which constitute analogues of 5-lipoxygenase inhibitors 4, is described. The route, representing a potential general method for benzofuran construction, proceeds from phenyl carbamate 11 and involves key directed ortho metalation (11 → 12), anionic ortho-Fries rearrangement (12 → 13a), and radical-induced cyclization (17a–c → 18a–c) steps.

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Hosseinian, Akram, Mirzaagha Babazadeh, Ladan Edjlali, Zahra Rahmani, and Esmail Vessally. "Intramolecular Cyclization of Aryl Propargyl Ethers: A Straightforward and Convenient Approach to Benzofuran Derivatives." Current Organic Synthesis 15, no. 7 (2018): 972–81. http://dx.doi.org/10.2174/1570179415666180829120105.

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Background: Benzofurans are very important structural motifs found in a great number of natural products and biologically active compounds. Many commercially available drugs, including citalopram, dronedarone, saprisartan, darifenacin, and galantamine are derived from benzofuran core entities. Due to the diversity of benzofuran derivatives in the therapeutic response profile, developing novel and truly efficient methods for their synthesis from low-cost and easily accessible starting materials in one-step has been the subject of number of papers in recent years. Objective: Propargylic ethers a

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Napiórkowska, Mariola, Marcin Cieślak, Julia Kaźmierczak-Barańska, Karolina Królewska-Golińska, and Barbara Nawrot. "Synthesis of New Derivatives of Benzofuran as Potential Anticancer Agents." Molecules 24, no. 8 (2019): 1529. http://dx.doi.org/10.3390/molecules24081529.

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The results of our previous research indicated that some derivatives of benzofurans, particularly halogeno-derivatives, are selectively toxic towards human leukemia cells. Continuing our work with this group of compounds we here report new data on the synthesis as well as regarding the physico-chemical and biological characterization of fourteen new derivatives of benzofurans, including six brominated compounds. The structures of all new compounds were established by spectroscopic methods (1H- and, 13C-NMR, ESI MS), and elemental analyses. Their cytotoxicity was evaluated against K562 (leukemi

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Rádl, Stanislav, Petr Hezký, Petr Konvička, and Ivan Krejčí. "Synthesis and Analgesic Activity of Some Substituted 1-Benzofurans and 1-Benzothiophenes." Collection of Czechoslovak Chemical Communications 65, no. 7 (2000): 1093–108. http://dx.doi.org/10.1135/cccc20001093.

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2-Benzoyl- and 2-(pyridylcarbonyl)-1-benzofuran-3-amines were prepared from 2-hydroxybenzonitrile and corresponding bromoethanone derivatives. 2-Benzoyl- and 2-(pyridylcarbonyl)-1-benzothiophene-3-amines were prepared analogously from 2-sulfanylbenzonitrile. 2-Benzoyl-1-benzofuran-3-amine treated with acetic anhydride or ethyl chloroformate provided the corresponding N-acetyl or N-ethoxycarbonyl derivatives. These N-activated compounds were alkylated with ethyl bromoacetate to provide ethyl N-acetyl-N-(2-benzoyl-1-benzofuran-3-yl)glycinate and ethyl N-(2-benzoyl-1-benzofuran-3-yl)-N-ethoxycarb

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Dissertations / Theses on the topic "Benzofuran – Synthesis"

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Mann, I. S. "The synthesis of benzofuran resorcinyl phytoalexins." Thesis, Imperial College London, 1988. http://hdl.handle.net/10044/1/47168.

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Thevenin, Marion. "Développement de nouveaux agents antiparasitaires : vers la synthèse totale de la cissampeloflavone et de dérivés." Phd thesis, Université Paris Sud - Paris XI, 2013. http://tel.archives-ouvertes.fr/tel-00871981.

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Les maladies tropicales provoquées par des parasites protozoaires tels que Trypanosoma brucei, Plasmodium falciparum et Leishmania donovani, infectent des milliards d'individus dans le monde et en tuent des millions chaque année. Actuellement, les phénomènes de résistance face aux thérapies actuelles utilisées pour traiter ces maladies dites " négligées " deviennent inquiétants et problématiques. Par conséquent, la découverte de nouvelles classes de molécules bioactives antiparasitaires est primordiale.C'est dans ce contexte que s'inscrit ce travail de thèse. La cissampeloflavone est un dimère

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Bekarlar, Merve Gokcen. "Synthesis Of Bishomo-inositol Derivatives." Master's thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613735/index.pdf.

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Inositols belong to an important class of biologically active compounds, named as cyclitols (cyclic polyols), which have attributed high interest in the past decade due to the glycosidase inhbition property that affects many biological processes. Initially, 1,3,3a,7a-tetrahydro-2-benzofuran (69) was synthesized as a key compound to synthesize bishomo-inositol derivatives. Then photooxygenation and manganese(III) acetate oxidation reactions of this key compound were studied in order to obtain isomeric inositol derivatives. Moreover, dihydroxylation and acid catalyzed ring opening reactions were

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Luniwal, Amarjit. "Design, Synthesis, and Process Chemistry Studies of Agents Having Anti-Cancer Properties." University of Toledo Health Science Campus / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=mco1302801948.

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Mahmood, Raza. "Synthesis of benzofurans and benzopyrans." Thesis, University of Hertfordshire, 2002. http://hdl.handle.net/2299/14039.

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Syntheses of 2,3-dihydrobenzofurans and 3,4-dihydrobenzopyrans normally involve several stages, therefore efficient syntheses of these compounds are desirable. A number of 3,4-dihydrobenzopyrans derivatives were prepared in one pot syntheses. The reaction is thought to proceed through cation intermediates, involving allylic cations generated by the reaction of allyl alcohols, 1,3-dienes, or diols in the presence of acids such as trifluoroacetic acid (TFA), or in a solution of glacial acetic and a metal catalyst or glacial acetic acid and sulphuric acid, followed by reaction with nucleophiles s

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Bombonato, Fernanda Irene. "Estudos visando à síntese do jungianol e a construção de anéis benzofurânicos utilizando TTN." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/46/46135/tde-04092007-145143/.

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Neste trabalho descrevemos os estudos visando à síntese do jungianol e a construção de anéis benzofurânicos. Em ambos os casos, a etapa chave da seqüência sintética é a reação de contração de anel mediada por tálio(III). O jungianol é um sesquiterpeno fenólico que foi isolado por Bohlmann et al., em 1977, da espécie Jungia malvaefolia. A etapa chave da síntese seria a reação do 1,2-diidro-5-metóxi-1,6-dimetilnaftaleno (intermediário-chave) com trinitrato de tálio (TTN), para dar origem ao esqueleto indânico presente no jungianol. Duas abordagens sintéticas foram utilizadas na tentativa de pr

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WALLEZ, VALERIE. "Conception et synthese de derives benzofuraniques, ligands potentiels des recepteurs de la melatonine (doctorat : pharmacochimie)." Lille 2, 1998. http://www.theses.fr/1998LIL2P261.

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Ahmad, Anees. "Exploring the iodine(III)-mediated ring contraction: new substrates, novel conditions and asymmetric reactions." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/46/46136/tde-29092015-145020/.

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In the first section this thesis includes the reactivity of various oxygen-containing benzofused cyclic alkenes with HTIB (Hydroxy(tosyloxy)iodobenzene). Instead of getting ring contraction products, 2H-chromene resulted in 4H-chromenes together with trans-addition products. Only cis-addition products were isolated from 4-methyl-2H-chromene. Ring contraction was observed in dihydrobenzoxepines and 2,2-dimethyl-2H-chromenes giving functionalized chromanes and benzofurans, respectively. In the second part, the ring contraction of 1,2-dihydronaphthalenes using HTIB was expanded to substrates be

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Stridfeldt, Elin. "Hypervalent Iodine Reagents in Metal-Free Arylations and Vinylations : Investigation of Suitable Coupling Partners and Synthesis of New Reagents." Doctoral thesis, Stockholms universitet, Institutionen för organisk kemi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-141580.

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This thesis concerns the development of metal-free reactions to obtain carbon-heteroatom and carbon-carbon bonds. This is achieved by transferring carbon ligands from hypervalent iodine reagents to suitable nucleophiles. The bulk of the work presented herein concerns arylation of oxygen and nitrogen nucleophiles, using the well-known diaryliodonium salts as aryl sources. In the first project, O-arylation of the oxime ethyl acetohydroxamate was studied. It was found that electron-poor as well as electron-rich aryl moieties could be transferred successfully to this nucleophile. Furthermore, the

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Meyer, Holger. "Pyrido[3,2-b]indol-4-yl-amine, [1]Benzofuro[3,2-b]pyridin-4-yl-amine und [1]Benzothieno[3,2-b]pyridin-4-yl-amine : Darstellung von Antimalariamitteln /." [S.l. : s.n.], 2003. http://www.gbv.de/dms/bs/toc/374105367.pdf.

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Books on the topic "Benzofuran – Synthesis"

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Wu, Xiao-Feng, and Yahui Li. Transition Metal-Catalyzed Benzofuran Synthesis: Transition Metal-Catalyzed Heterocycle Synthesis Series. Elsevier Science & Technology Books, 2017.

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Book chapters on the topic "Benzofuran – Synthesis"

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Verma, Nishant, Shaily, Kalpana Chauhan, and Sumit Kumar. "Benzofuran-3(2H)-Ones Derivatives: Synthesis, Docking and Evaluation of Their in Vitro Anticancer Studies." In Advances in Intelligent Systems and Computing. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5414-8_26.

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Wu, Xiao-Feng, and Yahui Li. "Pd-Catalyzed Benzofuran Synthesis." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00002-4.

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Wu, Xiao-Feng, and Yahui Li. "Cu-Catalyzed Benzofuran Synthesis." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00003-6.

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Wu, Xiao-Feng, and Yahui Li. "Other Transition Metal-Catalyzed Benzofuran Synthesis." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00004-8.

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Wu, Xiao-Feng, and Yahui Li. "Introduction." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00001-2.

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Wu, Xiao-Feng, and Yahui Li. "Traditional Synthesis of Benzo[b]furans." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00005-x.

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Wu, Xiao-Feng, and Yahui Li. "Summary and Outlook." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00006-1.

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"Front-matter." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00007-3.

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"Copyright." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00008-5.

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"Index." In Transition Metal-Catalyzed Benzofuran Synthesis. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-809377-1.00021-8.

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Conference papers on the topic "Benzofuran – Synthesis"

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Wang, Liqin, Shiqiang Cui, and Shouzhi Pu. "Synthesis and Properties of a Photochromic Diarylethene with a Benzofuran Ring." In 2012 Symposium on Photonics and Optoelectronics (SOPO 2012). IEEE, 2012. http://dx.doi.org/10.1109/sopo.2012.6271045.

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Liang, Yunfei, Renjie Wang, and Gang Liu. "Synthesis, photochromism and fluorescence of new diarylethene bearing a benzofuran unit." In 2017 3rd International Forum on Energy, Environment Science and Materials (IFEESM 2017). Atlantis Press, 2018. http://dx.doi.org/10.2991/ifeesm-17.2018.297.

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Li, Xiaoting, Weijun Liu, Shouzhi Pu, and Hui Li. "Synthesis and Properties of Photochromic Diarylethene Derivatives Bearing Benzofuran and Isoxazole Units." In 2012 Symposium on Photonics and Optoelectronics (SOPO 2012). IEEE, 2012. http://dx.doi.org/10.1109/sopo.2012.6271041.

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Yan, Peijian, Shouzhi Pu, and Shiqiang Cui. "Synthesis and application for optical recording of a novel diarylethene with benzofuran unit." In 2011 4th International Congress on Image and Signal Processing (CISP 2011). IEEE, 2011. http://dx.doi.org/10.1109/cisp.2011.6100544.

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Kammel, Richard, and Jiří Hanusek. "SYNTHESIS AND REARRANGEMENT OF SUBSTITUTED S-(1-BENZOFURAN-2(3H)-ONE-3-YL) ISOTHIURONIUM-BROMIDES." In The 17th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2013. http://dx.doi.org/10.3390/ecsoc-17-a044.

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Vektariene, Ausra, Gytis Vektaris, and Jiri Svoboda. "Theoretical study of the mechanism of thieno[3,2-b]benzofuran bromination." In The 12th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2008. http://dx.doi.org/10.3390/ecsoc-12-01284.

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Hejchman, E., and D. Maciejewska. "O-Subsituted Derivatives OF 2,3-dihydro-2,2-dimethyl-7-benzofuranol - Cytotoxic Activity and Structural Studies." In The 8th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01973.

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