Academic literature on the topic 'Benzohydrazides'

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Journal articles on the topic "Benzohydrazides"

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Alqahtani, Yahya S., Sravanthi Avunoori, Vaibhavi M. Kanimehalli, et al. "Synthesis, Docking Studies, and Biological Evaluation of Some New Pyrrolyl Benzohydrazide Derivatives." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 34, no. 01 (2024): 35. http://dx.doi.org/10.59467/ijhc.2024.34.35.

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A series of 16 new N-(2-(4-(1H-pyrrol-1-yl)phenoxy)acetyl)-N-substituted benzohydrazides was synthesized by the reaction of 1-(1H-pyrrol-1-yl)benzohydrazide with substituted benzoic acids in the presence of N,N-dimethylformamide, HBTU, and DIEA. Molecular docking and biological screening were done on the synthesized compounds to conduct antitubercular and antibacterial activity tests. The selected compounds were investigated for the inhibition of the InhA and DHFR enzymes. Promising antitubercular, antibacterial, and enzyme inhibitory action has been shown for all molecules. Absorption, distri
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Manikandan, V., S. Balaji, R. Senbagam, et al. "Synthesis and antimicrobial activities of some (E)-N'-1-(substituted benzylidene)benzohydrazides." International Journal of Advanced Chemistry 5, no. 1 (2017): 17. http://dx.doi.org/10.14419/ijac.v5i1.7155.

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About ten substituted (E)-N'-1-(substituted benzylidene) benzohydrazides have been synthesized. They are analyzed by their analytical, ultra violet (UV), Fourier transform-IR (FT-IR) and nuclear magnetic resonance (NMR) spectral data and evaluated by antimicrobial activities such antibacterial and antifungal activities.
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Meshcheryakova, A. A., K. S. Neumoina, and V. V. Sorokin. "Three-Component Synthesis of Spiropyrazolines Derived from Benzohydrazides." Russian Journal of Organic Chemistry 59, no. 8 (2023): 1309–14. http://dx.doi.org/10.1134/s1070428023080031.

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Soundarajan, Kamalakannan, Rathinam Periyasamy, and Thangamuthu Mohan Das. "Design and synthesis of sugar-benzohydrazides: low molecular weight organogelators." RSC Advances 6, no. 85 (2016): 81838–46. http://dx.doi.org/10.1039/c6ra18715c.

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A novel class of methyltriglycol benzohydrazide based N-glycosylamines containing long alkyl chain derivatives were synthesized in good yield and characterized using NMR (<sup>1</sup>H and <sup>13</sup>C) spectral analysis.
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Zhou, Yi-Xuan, Wei Li, and Zhonglu You. "Synthesis, Spectroscopic Characterization, Crystal Structures and Antibacterial Activity of Benzohydrazones Derived from 4-Pyridinecarboxaldehyde with Various Benzohydrazides." Acta Chimica Slovenica 70, no. 2 (2023): 240–46. http://dx.doi.org/10.17344/acsi.2023.8123.

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Reaction of 4-pyridinecarboxaldehyde with 3-hydroxy-4-methoxybenzohydrazide, 4-bromobenzohydrazide and 4-dimethylaminobenzohydrazide, respectively in methanol afforded three new benzohydrazones. They are 3-hydroxy-4-methoxy-N’-(pyridin-4-ylmethylene)benzohydrazide (1), 4-bromo-N’-(pyridin-4-ylmethylene)benzohydrazide (2), and 4-(dimethylamino)-N’-(pyridin-4-ylmethylene)benzohydrazide (3). The compounds have been characterized by elemental analysis, 1H and 13C NMR and IR spectroscopy, as well as single crystal X-ray diffraction. The antibacterial activities of the compounds against E. coli, P.
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Geffken, Detlef, and Maria Anna Köllner. "Cyclisierung von N′,N′-disubstituierten Anthranilsäurehydraziden mit 1,1′-Oxalyldiimidazol zu 4-Amino-2,3,4,5-tetrahydro-1H-1,4-benzodiaz- epin-2,3,5-trionen / Cyclization of N’,N’-Disubstituted Anthranilic Hydrazides with 1,1’-Oxalyldiimidazole to 4-Amino-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2,3,5-triones." Zeitschrift für Naturforschung B 60, no. 11 (2005): 1207–11. http://dx.doi.org/10.1515/znb-2005-1115.

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N’,N’-Disubstituted (2-phenylamino)-, (2-methylamino)- and (2-benzylamino)benzohydrazides (1) are cyclized by in situ prepared 1,1’-oxalyldiimidazole to give 3-amino-2,3,4,5-tetrahydro-1H- 1,4-benzodiazepine-2,3,5-triones 2 as the major product. Depending on the substituents of 1 competitive formation of quinazoline-2,4-diones 3 and 1,3,4-oxadiazoline-2-one 4 is observed. The formation of heterocycles 2, 3, 4 is rationalized via a common primary intermediate 1A.
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Mahnashi, Mater H., Sravanthi Avunoori, Sanjay Gopi, et al. "Synthesis, molecular docking study and biological evaluation of new pyrrole scaffolds as potential antitubercular agents for dual targeting of enoyl ACP reductase and dihydrofolate reductase." PLOS ONE 19, no. 5 (2024): e0303173. http://dx.doi.org/10.1371/journal.pone.0303173.

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In this study, new series of N’-(2-(substitutedphenoxy)acetyl)-4-(1H-pyrrol-1-yl)benzohydrazides (3a-j) 4-(2,5-dimethyl-1H-pyrrol-1-yl)-N’-(2-(substitutedphenoxy)acetyl)benzohydrazides (5a-j) were synthesized, characterized and assessed as inhibitors of enoyl ACP reductase and DHFR. Most of the compounds exhibited dual inhibition against the enzymes enoyl ACP reductase and DHFR. Several synthesized substances also demonstrated significant antibacterial and antitubercular properties. A molecular docking analysis was conducted in order to determine the potential mechanism of action of the synthe
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Krátký, Martin, Šárka Štěpánková, Michaela Brablíková, Katarína Svrčková, Markéta Švarcová, and Jarmila Vinšová. "Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors." Current Topics in Medicinal Chemistry 20, no. 23 (2020): 2106–17. http://dx.doi.org/10.2174/1568026620666200819155503.

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Background: Hydrazide-hydrazones have been known as scaffold with various biological activities including inhibition of acetyl- (AChE) and butyrylcholinesterase (BuChE). Cholinesterase inhibitors are mainstays of dementias’ treatment. Objective: Twenty-five iodinated hydrazide-hydrazones and their analogues were designed as potential central AChE and BuChE inhibitors. Methods: Hydrazide-hydrazones were synthesized from 4-substituted benzohydrazides and 2-/4- hydroxy-3,5-diiodobenzaldehydes. The compounds were investigated in vitro for their potency to inhibit AChE from electric eel and BuChE f
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Taghavi, Ali, Samir Nasir, Marcus Pickhardt, et al. "N′-Benzylidene-Benzohydrazides as Novel and Selective Tau-PHF Ligands." Journal of Alzheimer's Disease 27, no. 4 (2011): 835–43. http://dx.doi.org/10.3233/jad-2011-111238.

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Çapan, İrfan. "Synthesis of carbazole-based acetyl benzohydrazides targeting urease enzyme inhibition." Organic Communications, no. 2 (August 18, 2021): 1–10. http://dx.doi.org/10.25135/acg.oc.109.2107.2140.

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Dissertations / Theses on the topic "Benzohydrazides"

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Phillips, Sarah F. "A Photophysical Characterization on the Unique Properties of Perylene-3,4:9,10-bis((3,4,5(tris(oxtyloxy)benzohydrazide)-dicarboximide." University of Akron / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=akron1249081748.

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Phillips, Sarah F. "A photophysical characterization on the unique properties of perylene-3,4:9,10-BIS((3,4,5(tris(octyloxy)benzohydrazide)-dicarboximide." Akron, OH : University of Akron, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=akron1249081748.

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Thesis (M.S.)--University of Akron, Dept. of Chemistry, 2009.<br>"August, 2009." Title from electronic thesis title page (viewed 10/14/2009) Advisor, David A. Modarelli; Faculty reader, Matthew P. Espe; Department Chair, Kim C. Calvo; Dean of the College, Chand Midha; Dean of the Graduate School, George R. Newkome. Includes bibliographical references.
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Book chapters on the topic "Benzohydrazides"

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Arjun, H. A., Ravi Kumar Rajan, R. Elancheran, et al. "In Silico and In Vitro Studies of Benzohydrazide Analogues as Potent Androgen Receptor Antagonist." In Special Publications. Royal Society of Chemistry, 2019. http://dx.doi.org/10.1039/9781839160783-00103.

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Stadlbauer, W. "From Benzohydrazides and Hydrazones of Aldehydes and Ketones." In Five-Membered Hetarenes with Two Nitrogen or Phosphorus Atoms. Georg Thieme Verlag KG, 2002. http://dx.doi.org/10.1055/sos-sd-012-00314.

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Conference papers on the topic "Benzohydrazides"

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Uğurlu, Güventürk, and Hacali Necefoğlu. "Theoretical investigation on structural, electronic and the nonlinear optical properties of 2- and 4-substituted benzohydrazides." In TURKISH PHYSICAL SOCIETY 33RD INTERNATIONAL PHYSICS CONGRESS (TPS33). Author(s), 2018. http://dx.doi.org/10.1063/1.5025972.

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Simijonović, Dušica, Marko Antonijević, Edina Avdović, Zorica Petrović, and Zoran Marković. "INHIBITORY EFFECT OF COUMARIN BENZOYLHYDRAZONES ON MCL-1 PROTEIN." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.442s.

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The protein that controls cell differentiation in acute myeloid leukemia is MCL-1. High-level of this protein causes the carcinogenesis. In this paper inhibitory effect of two coumarin benzoylhydrazones,(E)-2-hydroxy-N’-(1-(2-oxo-2H-chromen-3-yl)ethylidene)benzohydrazide (A) and (E)-4-hydroxy-N’-(1-(2-oxo-2H-chromen-3-yl)ethylidene)benzohydrazide (B) against MCL-1 protein was investigated. For this purpose, a molecular docking simulations were used. The obtained results showed that compound A showed better activity than compound B. Also, the docking simulations against MCL-1 protein were perfo
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Vineetha, M. C., and M. R. Prathapachandra Kurup. "Spectral and biological studies of copper complex of (Z)-N’-(3,5-dichloro-2-hydroxybenzylidene) benzohydrazide." In INTERNATIONAL CONFERENCE ON SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS: STAM 20. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018125.

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Setyawati, Amri, Tutik Dwi Wahyuningsih, and Bambang Purwono. "Synthesis and characterization of novel benzohydrazide as potential antibacterial agents from natural product vanillin and wintergreen oil." In PROCEEDINGS FROM THE 14TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND. Author(s), 2017. http://dx.doi.org/10.1063/1.4978194.

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Antonijevic, Marko, Dejan Milenkovic, Ana Kesic, Edina Avdovic, and Zoran Markovic. "ANTIRADIKALSKI KAPACITET (E)-N’-1-(2,4-DIOKSO-2H-HROMEN-3(4H)-ILIDENE)ETIL)-4-HIDROKSI-3-METOKSIBENZOHIDRAZIDA." In XXVI savetovanje o biotehnologiji sa međunarodnim učešćem. University of Kragujevac, Faculty of Agronomy, 2021. http://dx.doi.org/10.46793/sbt26.423a.

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Coumarins are a widespread group of compounds. They have a wide range of physiological effects, from antifungal, through anticoagulant to anticancer, and therefore they have found wide application in the treatment of various diseases. In this paper, the ability of 4-hydroxy-3-methoxy-N'-((E)-1-(2,4-dioxo-2H-chromen-3(4H)-ylidene)ethyl)benzohydrazide to inactivate ROS was investigated. The analysis of the obtained results showed that the SET-PT (Single Electron Transfer Followed By Proton Transfer) mechanism is non-operative. On the other hand, the thermodynamic parameters describing the HAT *H
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Abidiy, Syafri Izzat, Triyanda Gunawan, Yusuf Syahril Alam, et al. "Antiviral activity of hydrazone derivatives based benzohydrazide/2-thiohydantoin analogs against HPV-18 (Human papillomavirus) : In silico study." In THE FOURTH AL-NOOR INTERNATIONAL CONFERENCE FOR SCIENCE AND TECHNOLOGY (4NICST2022). AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0206875.

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Ali, Tarik. "Reaction of 2-hydroxy-N`-[(4-oxo-4H-chromen-3-yl)methylidene]benzohydrazide with some phosphorus reagents: Synthesis and evaluation of anticancer activities of some novel α-hydrazinophosphonic acid, 1,4,5,2-oxadiazaphosphinines and 1,3,2-benzoxaza-phosphinines bearing a chromone ring." In The 20th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecsoc-20-b020.

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