Academic literature on the topic 'Benzoxazole derivatives'

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Journal articles on the topic "Benzoxazole derivatives"

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Özil, Musa, and Emre Menteşe. "Microwave-assisted Synthesis of Benzoxazoles Derivatives." Current Microwave Chemistry 7, no. 3 (2020): 183–95. http://dx.doi.org/10.2174/2213335607999200518094114.

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Background: Benzoxazole, containing a 1,3-oxazole system fused with a benzene ring, has a profound effect on medicinal chemistry research owing to its important pharmacological activities. On the other hand, the benzoxazole derivative has exhibited important properties in material science. Especially in recent years, microwave-assisted synthesis is a technique that can be used to increase diversity and quick research in modern chemistry. The utilization of microwave irradiation is beneficial for the synthesis of benzoxazole in recent years. In this focused review, we provide a metaanalysis of
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Journal, Baghdad Science. "Synthesis of Some Heterocyclic Compounds Derived from 2-Mercapto Benzoxazole." Baghdad Science Journal 10, no. 3 (2013): 766–78. http://dx.doi.org/10.21123/bsj.10.3.766-778.

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New series of 2-mecapto benzoxazole derivatives (1-20) incorporated into fused to different nitrogen and suphur containing heterocyclic were prepared from 2-meracpto benzoxazole, when treated with hydrazine hydrate to afford 2-hydrazino benzoxazol (1). Compound (1) converted to a variety of pyridazinone andphthalazinone derivatives (2-4) by reaction with different carboxylic anhydride. Also, reaction of (1) with phenyl isothiocyanate and ethyl chloro acetate afforded 3-phenyl-1,3-thiazolidin-2,4-dione-2-(benzoxazole-2-yl-hydrazone) (6). Azomethines (7-10) were prepared through reaction of (1)
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Askar, Firyal W., Huda A. Hassan, and Nahida A. Jinzeel. "Synthesis of Some Heterocyclic Compounds Derived from 2-Mercapto Benzoxazole." Baghdad Science Journal 10, no. 3 (2013): 766–78. http://dx.doi.org/10.21123/bsj.2013.10.3.766-778.

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New series of 2-mecapto benzoxazole derivatives (1-20) incorporated into fused to different nitrogen and suphur containing heterocyclic were prepared from 2-meracpto benzoxazole, when treated with hydrazine hydrate to afford 2-hydrazino benzoxazol (1). Compound (1) converted to a variety of pyridazinone andphthalazinone derivatives (2-4) by reaction with different carboxylic anhydride. Also, reaction of (1) with phenyl isothiocyanate and ethyl chloro acetate afforded 3-phenyl-1,3-thiazolidin-2,4-dione-2-(benzoxazole-2-yl-hydrazone) (6). Azomethines (7-10) were prepared through reaction of (1)
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Rakas, Anja, Leentje Persoons, Dirk Daelemans, Dajana Kučić Grgić, and Tatjana Gazivoda Kraljević. "A Sustainable Synthesis of Novel 2-(3,4-Disubstituted phenyl)benzoxazole Derivatives and Their Antiproliferative and Antibacterial Evaluation." Molecules 30, no. 8 (2025): 1767. https://doi.org/10.3390/molecules30081767.

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This study describes the synthesis of O-alkylated benzaldehydes 1–8, Schiff bases 9–28, and benzoxazole derivatives 29–48 using microwave, ultrasound, and mechanochemical reactions, as well as reactions in deep eutectic solvents in excellent yields, and their antiproliferative and antibacterial activities. The in vitro evaluation of antiproliferative activity for the newly synthesised benzoxazole derivatives 29–48 against a diverse panel of human cancer cell lines, such as LN-229, Capan-1, HCT-116, NCI-H460, DND-41, HL-60, K-562, and Z-138 demonstrated that the majority of these benzoxazole de
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Staniszewska, Monika, Łukasz Kuryk, Aleksander Gryciuk, et al. "In Vitro Anti-Candida Activity and Action Mode of Benzoxazole Derivatives." Molecules 26, no. 16 (2021): 5008. http://dx.doi.org/10.3390/molecules26165008.

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A newly synthetized series of N-phenacyl derivatives of 2-mercaptobenzoxazole, including analogues of 5-bromo- and 5,7-dibromobenzoxazole, were screened against Candida strains and the action mechanism was evaluated. 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(4-bromophenyl)ethanone (5d), 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(2,3,4-trichloro-phenyl)ethanone (5i), 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(2,4,6-trichlorophenyl)ethanone (5k) and 2-[(5-bromo-1,3-benzoxazol-2-yl)sulfanyl]-1-phenylethanone (6a) showed anti-C. albicans SC5314 activity, where 5d displayed MICT = 16 µg/mL (%R = 100) and a weak anti-prol
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Zou, Yue, Yong Zhang, Xing Liu, et al. "Research Progress of Benzothiazole and Benzoxazole Derivatives in the Discovery of Agricultural Chemicals." International Journal of Molecular Sciences 24, no. 13 (2023): 10807. http://dx.doi.org/10.3390/ijms241310807.

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Benzoxazole and benzothiazole have a broad spectrum of agricultural biological activities, such as antibacterial, antiviral, and herbicidal activities, which are important fused heterocyclic scaffold structures in agrochemical discovery. In recent years, great progress has been made in the research of benzoxazoles and benzothiazoles, especially in the development of herbicides and insecticides. With the widespread use of benzoxazoles and benzothiazoles, there may be more new products containing benzoxazoles and benzothiazoles in the future. We systematically reviewed the application of benzoxa
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Mabied, Ahmed F., Elsayed M. Shalaby, Hamdia A. Zayed, Esmat El-Kholy, Ibrahim S. A. Farag, and Naima A. Ahmed. "Crystal Structure and Stereochemistry Study of 2-Substituted Benzoxazole Derivatives." ISRN Organic Chemistry 2014 (May 13, 2014): 1–7. http://dx.doi.org/10.1155/2014/728343.

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The structure of 2-[(4-chlorophenylazo) cyanomethyl] benzoxazole, C15H9ClN4O (I), has triclinic (P1̅) symmetry. The structure displays N–H⋯N hydrogen bonding. The structure of 2-[(arylidene) cyanomethyl] benzoxazoles, C17H10N2O3 (II), has triclinic (P1̅) symmetry. The structure displays C–H⋯N, C–H⋯C hydrogen bonding. In (I), the chlorophenyl and benzoxazole groups adopt a trans configuration with respect to the central cyanomethyle hydrazone moiety. Compound (II) crystallized with two molecules in the asymmetric unit shows cisoid conformation between cyano group and benzoxazole nitrogen, contr
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Danilenko, Nadezhda, Vladimir Shmalyuk, and Andrei Khlebnikov. "2-(2-(Fluorosulfonyloxy)phenyl)benzoxazole." Molbank 2021, no. 3 (2021): M1242. http://dx.doi.org/10.3390/m1242.

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The fluorosulfate derivatives of benzoxazole attract attention since benzoxazole-based compounds have a wide range of biological activities, and the ability of the –SO2F group to react with various functional groups makes it possible to synthesize various new derivatives. The new 2-(2-(fluorosulfonyloxy)phenyl)benzoxazole (2) has been synthesized by the SuFEx click reaction in a two-chamber reactor. Compound 2 is the first example of a benzoxazole derivative with a fluorosulfate-containing substituent at position two of the benzoxazole heterocycle. The anti-cancer potency of 2 was evaluated in
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Abdelgawad, Mohamed A., Mohammad M. Al-Sanea, Mohamed A. Zaki, et al. "New Benzoxazole Derivatives as Antiprotozoal Agents: In Silico Studies, Synthesis, and Biological Evaluation." Journal of Chemistry 2021 (March 3, 2021): 1–11. http://dx.doi.org/10.1155/2021/6631868.

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Background. Benzoxazole derivatives have different biological activities. In pursuit of designing novel chemical entities with antiprotozoal and antimicrobial activities, benzoxazolyl aniline was utilized as a privileged scaffold of a series of (3-benzoxazole-2-yl) phenylamine derivatives, 3-benzoxazoloyl acetamide, and butyramide derivatives. Methods. These novel analogs were synthesized in straightforward simple chemistry without any quantitative chromatographic separations in reasonable yields. The biological evaluation of all target compounds as potential antimalarial, antileishmanial, ant
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Glamočlija, Una, Subhash Padhye, Selma Špirtović-Halilović, et al. "Synthesis, Biological Evaluation and Docking Studies of Benzoxazoles Derived from Thymoquinone." Molecules 23, no. 12 (2018): 3297. http://dx.doi.org/10.3390/molecules23123297.

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Thymoquinone (TQ), a natural compound with antimicrobial and antitumor activity, was used as the starting molecule for the preparation of 3-aminothymoquinone (ATQ) from which ten novel benzoxazole derivatives were prepared and characterized by elemental analysis, IR spectroscopy, mass spectrometry and NMR (1H, 13C) spectroscopy in solution. The crystal structure of 4-methyl-2-phenyl-7-isopropyl-1,3-benzoxazole-5-ol (1a) has been determined by X-ray diffraction. All compounds were tested for their antibacterial, antifungal and antitumor activities. TQ and ATQ showed better antibacterial activit
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Dissertations / Theses on the topic "Benzoxazole derivatives"

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Slaybaugh, Amy. "Structure-Property Relationships In PAEs Prepared From 2-(2,4-difluorophenyl)benzoxazole Derivatives." Wright State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=wright1526553989709853.

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Tseng, Ting-yu, and 曾亭瑜. "The Odd-even Effects in Dimeric Benzoxazole Derivatives." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/09644043708453719179.

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碩士<br>國立中央大學<br>化學研究所<br>95<br>Liquid crystalline dimers, known so-called twins or bimesogens have attracted great attentions. This type of mesogenic structures was generally constructed by connecting either two identical or non-identifcal mesogenic moieties through a flexible central spacer. The structural conformation and mesomorphic properties observed by this type of LC dimers are quite different from conventional molecular mesogens, and also significantly influenced by the structure and the spacer length and the linker group as well. The mesomorphic properties of such dimeric compounds we
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Wu, I.-tzu, and 吳宜姿. "Metallomesogens Derived from Benzoxazole and cis-Enaminoketones Derivatives." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/78301665270555518788.

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碩士<br>國立中央大學<br>化學研究所<br>99<br>In series I the synthesis, characterization and mesomorphic behavior of a series of benzoxazole derivatives 2 and their complexes 1 (M = Pd, Cu, Zn) are described. The mesomorphic properties were investigated using polarized optical microscopy (POM), differential scanning calorimetry (DSC), powder X-ray diffraction (XRD). The results indicated that ligands based on benzoxazole with carbon length of n = 10, 12 showed smectic A (SmA) mesophase. All copper (II) and zinc (II) complexes were not mesogenic. However, palladium (II) comlexes with carbon length of n = 10,
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chu, kai jae, and 邱凱傑. "nitration.sulfonation of polystyrene and their derivatives of reactive dye and benzoxazole." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/96513996023440161537.

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碩士<br>國立中央大學<br>化學工程學系<br>85<br>The reuse waste foaming polystyrene(PS) have received considerable attention for years . In order to resolve the pollution of PS , we try to sythetize reactive-dyes or benzoxazole compounds from PS .We are going to use a recycle waste polystyrene , porilon , such as some process of nitration 、sulfonation and then reduction to get active amino and water soluable sulfonic group on the phenyl of polystyrene .The amino function will be reacted with first chloro o
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Wang, Chung-Shu, and 王崇旭. "The Effect of Terminal Functional Group on Mesomorphic Properties of Benzoxazole Derivatives." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/21502841229740618182.

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碩士<br>國立中央大學<br>化學研究所<br>92<br>Abstract In this thesis, we report the synthesis, characterization and mesomorphic properties of two novel series of new mesogenic derivatives based on [4-(6-alkoxybenzoxazol-2-yl)phenyl]-4-X-benzy lidenes (as shown below, X = CN, F, Cl, NO2, OCH3 and etc.) and metal complexes of 5-alkoxy-2-{[4-(6-alkoxybenzoxazol-2-yl)phenylimino] methyl}phenols. These compounds were all characterized by 1H-NMR and 13C-NMR spectroscopy, and their mesomorphic properties were studied by differential scanning calorimeter (DSC) and polarized optical microscopy (POM). The results ind
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Dnyaneshwar, Shriram Raut, Roberto Bartolino, Gabriele Bartolo, and Raffaella Mancuso. "Pdl2 catalyzed oxidative carbonylation of anime derivatives leading to macrolactam, urea, oxamide, oxazolidinone and benzoxazolone derivatives." Thesis, 2014. http://hdl.handle.net/10955/1268.

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CHEN, YI, and 陳宜. "Characteristics of curing reaction and properties of crosslinked resins of the reactive blends of Meldrum’s acid derivatives and benzoxazine compounds." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/91870284849921249812.

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碩士<br>國立清華大學<br>化學工程學系<br>104<br>This study focuses on Meldrum’s acid (MA) polymerization mechanism as well as the properties of the correspond crosslinked polymers. In the first part, MA derivatives are blended with benzoxazine compound (F-BZ) with tertiary amine structure, which is a Lewis base, to undergo thermolysis at a much lower temperature. By means of DSC, TGA, FT-IR and NMR characterization, we confirmed its catalytic effect and mechanism. Furthermore, by this reaction mechanism, different equivalent MA derivative (MA-F) are applied to modify polybenzoxazine. Results indicate polymer
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Books on the topic "Benzoxazole derivatives"

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Konda, Swathi. Development of Biologically Active Benzoxazole Derivatives. Lulu Press, Inc., 2015.

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Book chapters on the topic "Benzoxazole derivatives"

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Pang, Yi, and Weihua Chen. "Excited-State Intramolecular Proton Transfer in 2-(2′-Hydroxyphenyl)benzoxazole Derivatives." In Hydrogen Bonding and Transfer in the Excited State. John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470669143.ch32.

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Neelima, G., K. Lakshmi, and K. Sesha Maheswaramma. "In Silico Studies of Benzoxazole Derivatives Using Ferrite-L-cysteine Magnetic Nanoparticles: Green Synthesis." In Special Publications. Royal Society of Chemistry, 2019. http://dx.doi.org/10.1039/9781839160783-00288.

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Singhal, Manisha, and Vinay Prabha Sharma. "Synthesis and Medicinal Importance of Benzoxazine, Benzoxazinone and Their Derivatives: A Short Review." In Springer Proceedings in Earth and Environmental Sciences. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79065-3_2.

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Prashanth, G. K., Srilatha Rao, H. S. Lalithamba, et al. "Benzoxazoles." In Advances in Chemical and Materials Engineering. IGI Global, 2025. https://doi.org/10.4018/979-8-3693-7267-8.ch008.

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Benzoxazoles are heterocyclic compounds featuring a benzene ring fused to an oxazole ring. They have attracted significant attention in medicinal chemistry due to their diverse biological activities. Many pharmacological compounds have a core structure called a heterocyclic scaffold, which is essential to their therapeutic actions. Modest alterations to this fundamental structure may result in notable variations in the medication's mechanism of action. Benzoxazole and its derivatives have shown substantial and noteworthy therapeutic effects. This chapter explores the synthesis, structural char
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Kantlehner, W. "Synthesis from Benzoxazole-2-thiones." In Three Carbon-Heteroatom Bonds: Ketenes and Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-024-00421.

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Gigante, B., A. M. Lobo, S. Prabhakar, M. J. Marcelo-Curto, and D. J. Williams. "Studies on the Catalytic Hydrogenation of Resin Acids Derivatives: Synthesis of a Benzoxazole." In Studies in Surface Science and Catalysis. Elsevier, 1991. http://dx.doi.org/10.1016/s0167-2991(08)61123-4.

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Parlapalli, Arunadevi, Kishore, Manasa Cidda, and Sarangapani Manda. "2-Amino-N-(Substituted Alkyl) Benzoxazole-5- Carboxamide Derivatives as Antiinflammatory and Antioxidant Drugs." In Current Overview on Pharmaceutical Science Vol. 2. B P International (a part of SCIENCEDOMAIN International), 2023. http://dx.doi.org/10.9734/bpi/cops/v2/8236f.

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Tasdelen, Mehmet Atilla, Baris Kiskan, Burcin Gacal, Fatmanur Kasapoglu, Luminita Cianga, and Yusuf Yagci. "Light-Induced Reactions of Benzoxazines and Derivatives." In Handbook of Benzoxazine Resins. Elsevier, 2011. http://dx.doi.org/10.1016/b978-0-444-53790-4.00054-0.

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Conference papers on the topic "Benzoxazole derivatives"

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Etcheverry, L. P., F. S. Rodembusch, H. I. Boudinov, A. Gundel, and E. C. Moreira. "Photoactive thin films based on benzoxazole derivatives." In 2015 30th Symposium on Microelectronics Technology and Devices (SBMicro). IEEE, 2015. http://dx.doi.org/10.1109/sbmicro.2015.7298109.

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Soares, Ana, Susana Costa, and M. Sameiro Gonçalves. "Benzoxazole Derivatives as Phototriggers for the Release of Butyric Acid." In The 18th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2014. http://dx.doi.org/10.3390/ecsoc-18-a034.

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Ryu, Hwani, Bitna Seo, Jooyoung Kim, In-Sung Jung, Jie-Young Song, and Jiyeon Ahn. "Abstract 1355: A novel derivative of benzoxazole enhances radiosensitivity of human colon cancer cells through p53-mediated G2/M arrest and mitochondrial apoptotic pathway." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1355.

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Reports on the topic "Benzoxazole derivatives"

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Chirachanchai, Suwabun. A Novel ion extraction material derived from silica surface modified silybenzoxazine derivatives via host-guest properties. Chulalongkorn University, 2001. https://doi.org/10.58837/chula.res.2001.81.

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Silylbenzoxazine derivatives with different bulky group on benzene ring are synthesized employing aminosilane as a primary amine. The silylbenzoxazine derivatives with more bulky group exhibit low ion extraction percentage due to the difficulty of molecular assembly formation as a result of the bulky group repulsion combining with the long alkyl chain of silane. Silica surface modified benzoxazines are successfully achieved via silylbenzoxazine derivatives and show the ion extraction property for various alkali and alkaline earth metal ions. When silane is coupled onto silica, the benzoxazine
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