Academic literature on the topic 'Benzoxazole – Synthesis'

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Journal articles on the topic "Benzoxazole – Synthesis"

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Özil, Musa, and Emre Menteşe. "Microwave-assisted Synthesis of Benzoxazoles Derivatives." Current Microwave Chemistry 7, no. 3 (2020): 183–95. http://dx.doi.org/10.2174/2213335607999200518094114.

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Background: Benzoxazole, containing a 1,3-oxazole system fused with a benzene ring, has a profound effect on medicinal chemistry research owing to its important pharmacological activities. On the other hand, the benzoxazole derivative has exhibited important properties in material science. Especially in recent years, microwave-assisted synthesis is a technique that can be used to increase diversity and quick research in modern chemistry. The utilization of microwave irradiation is beneficial for the synthesis of benzoxazole in recent years. In this focused review, we provide a metaanalysis of
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Journal, Baghdad Science. "Synthesis of Some Heterocyclic Compounds Derived from 2-Mercapto Benzoxazole." Baghdad Science Journal 10, no. 3 (2013): 766–78. http://dx.doi.org/10.21123/bsj.10.3.766-778.

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New series of 2-mecapto benzoxazole derivatives (1-20) incorporated into fused to different nitrogen and suphur containing heterocyclic were prepared from 2-meracpto benzoxazole, when treated with hydrazine hydrate to afford 2-hydrazino benzoxazol (1). Compound (1) converted to a variety of pyridazinone andphthalazinone derivatives (2-4) by reaction with different carboxylic anhydride. Also, reaction of (1) with phenyl isothiocyanate and ethyl chloro acetate afforded 3-phenyl-1,3-thiazolidin-2,4-dione-2-(benzoxazole-2-yl-hydrazone) (6). Azomethines (7-10) were prepared through reaction of (1)
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Imramovsky, Ales, Jan Kozic, Matus Pesko, et al. "Synthesis and Antimycobacterial and Photosynthesis-Inhibiting Evaluation of 2-[(E)-2-Substituted-ethenyl]-1,3-benzoxazoles." Scientific World Journal 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/705973.

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A series of twelve 2-[(E)-2-substituted-ethenyl]-1,3-benzoxazoles was designed. All the synthesized compounds were tested against three mycobacterial strains. The compounds were also evaluated for their ability to inhibit photosynthetic electron transport (PET) in spinach (Spinacia oleraceaL.) chloroplasts. 2-[(E)-2-(4-Methoxyphenyl)ethenyl]-1,3-benzoxazole, 2-[(E)-2-(2,3-dihydro-1-benzofuran-5-yl)ethenyl]-1,3-benzoxazole and 2-{(E)-2-[4-(methylsulfanyl)phenyl]ethenyl}-1,3-benzoxazole showed the highest activity againstM. tuberculosis,M. kansasii,andM. avium, and they demonstrated significantl
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Glamočlija, Una, Subhash Padhye, Selma Špirtović-Halilović, et al. "Synthesis, Biological Evaluation and Docking Studies of Benzoxazoles Derived from Thymoquinone." Molecules 23, no. 12 (2018): 3297. http://dx.doi.org/10.3390/molecules23123297.

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Thymoquinone (TQ), a natural compound with antimicrobial and antitumor activity, was used as the starting molecule for the preparation of 3-aminothymoquinone (ATQ) from which ten novel benzoxazole derivatives were prepared and characterized by elemental analysis, IR spectroscopy, mass spectrometry and NMR (1H, 13C) spectroscopy in solution. The crystal structure of 4-methyl-2-phenyl-7-isopropyl-1,3-benzoxazole-5-ol (1a) has been determined by X-ray diffraction. All compounds were tested for their antibacterial, antifungal and antitumor activities. TQ and ATQ showed better antibacterial activit
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Staniszewska, Monika, Łukasz Kuryk, Aleksander Gryciuk, et al. "In Vitro Anti-Candida Activity and Action Mode of Benzoxazole Derivatives." Molecules 26, no. 16 (2021): 5008. http://dx.doi.org/10.3390/molecules26165008.

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A newly synthetized series of N-phenacyl derivatives of 2-mercaptobenzoxazole, including analogues of 5-bromo- and 5,7-dibromobenzoxazole, were screened against Candida strains and the action mechanism was evaluated. 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(4-bromophenyl)ethanone (5d), 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(2,3,4-trichloro-phenyl)ethanone (5i), 2-(1,3-benzoxazol-2-ylsulfanyl)-1-(2,4,6-trichlorophenyl)ethanone (5k) and 2-[(5-bromo-1,3-benzoxazol-2-yl)sulfanyl]-1-phenylethanone (6a) showed anti-C. albicans SC5314 activity, where 5d displayed MICT = 16 µg/mL (%R = 100) and a weak anti-prol
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Kumar, Dinesh, Santosh Rudrawar, and Asit K. Chakraborti. "One-Pot Synthesis of 2-Substituted Benzoxazoles Directly from Carboxylic Acids." Australian Journal of Chemistry 61, no. 11 (2008): 881. http://dx.doi.org/10.1071/ch08193.

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Methanesulfonic acid has been found to be a highly effective catalyst for a convenient and one-pot synthesis of 2-substituted benzoxazoles by the reaction of 2-aminophenol with acid chlorides, generated in situ from carboxylic acids. Aryl, heteroaryl, and arylalkyl carboxylic acids provided excellent yields of the corresponding benzoxazoles. The reaction conditions were compatible with various substituents such as chloro, bromo, nitro, methoxy, cyclopentyloxy, phenoxy, thiophenoxy, and conjugated double bonds. Benzoxazole formation was found to be general with respect to substituted 2-aminophe
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Aruna, G., Ravindra Kulkarni, Baswaraj Machaa, Malathi Jojula, Shravan Gunda, and G. Achaiah. "Design, Synthesis and Evaluation of Aryloxybenzylidene Hydrazinyl-Benzoxazoles/Benzothiazoles Analogs as Antimycobacterial Agents." Asian Journal of Organic & Medicinal Chemistry 5, no. 3 (2020): 185–91. http://dx.doi.org/10.14233/ajomc.2020.ajomc-p272.

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Substituted 2-(2-(4-aryloxybenzylidene)hydrazinyl)benzothiazole/benzoxazoles series were designed through molecular hybridization and synthesized in condensation reaction of hydrazinylbenzothiazole/ benzoxazole with substituted aryloxy benzaldehydes. All the synthesized compounds were assigned structure based on spectral data and were evaluated for antimycobacterial activity. Among both benzothiazole and benzoxazole derivatives, the compounds 8f and 9e were found to show most potent antitubercular activity with MIC value of 0.89 and 0.92 μM which are on a par with those of standard antitubercu
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Yang, Po, and Yi Gu. "Synthesis of a novel benzoxazine containing benzoxazole structure." Chinese Chemical Letters 21, no. 5 (2010): 558–62. http://dx.doi.org/10.1016/j.cclet.2009.12.012.

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Abdelgawad, Mohamed A., Mohammad M. Al-Sanea, Mohamed A. Zaki, et al. "New Benzoxazole Derivatives as Antiprotozoal Agents: In Silico Studies, Synthesis, and Biological Evaluation." Journal of Chemistry 2021 (March 3, 2021): 1–11. http://dx.doi.org/10.1155/2021/6631868.

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Background. Benzoxazole derivatives have different biological activities. In pursuit of designing novel chemical entities with antiprotozoal and antimicrobial activities, benzoxazolyl aniline was utilized as a privileged scaffold of a series of (3-benzoxazole-2-yl) phenylamine derivatives, 3-benzoxazoloyl acetamide, and butyramide derivatives. Methods. These novel analogs were synthesized in straightforward simple chemistry without any quantitative chromatographic separations in reasonable yields. The biological evaluation of all target compounds as potential antimalarial, antileishmanial, ant
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Rostom, Sherif, Hesharn Fahmy, and Manal Ssaudi. "Synthesis and in vitro Anti-HIV Screening of Certain 2-(Benzoxazol-2-ylamino)-3H-4-oxopyrimidines." Scientia Pharmaceutica 71, no. 2 (2003): 57–74. http://dx.doi.org/10.3797/scipharm.aut-03-08.

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Intensive efforts are underway worldwide to develop chemotherapeutic agents effective against HIV, the etiological agent of AIDS. In this view, it was designed to synthesize and investigate the anti-HIV activity of some new 2-(benzoxazol-2-ylamino)-3H-4-oxopyrimidines following the lead benzoxazole (L 697, 661), which was reported to inhibit the spread of the HIV infection by 95 % in MT4 cell culture. Only the 2-(benzoxazol-2-ylarnino)-6-hydroxy-3H-4-oxopyrdine 8 (NSC 722448) was confirmed to exhibit moderate in vitro anti-HIV activity (percentage of protection 76.83 %).
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Dissertations / Theses on the topic "Benzoxazole – Synthesis"

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Kleinhans, Dewald Johannes. "Studies in the synthesis of benzoxazole compounds." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/97900.

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Thesis (PhD)--Stellenbosch University, 2015.<br>ENGLISH ABSTRACT: Benzoxazoles are an important class of π-electron-excessive, benzene-fused heterocyclic compounds found in natural products and display a wide range of pharmacological applications. It is therefore a widely used starting scaffold for drug and agrochemical discovery programs. Other applications include: chiral auxiliaries in asymmetric reactions, chiral receptors for the resolution of racemic mixtures, fluorescent whitening dyes, various photochromic materials and as ligands for a wide range of catalytic reactions. Due to ou
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Park, Joonwon. "Synthesis and molecular control of star-like poly-2,4-benzoxazole." Thesis, Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/8656.

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Avant, Lavern Marshall. "Synthesis and characterization of a cross-digitated poly (2,5-Benzoxazole) (ABPBO)." Thesis, Georgia Institute of Technology, 1995. http://hdl.handle.net/1853/8464.

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Bi, Xiaoman bi. "Synthesis and Characterization of Novel Fluorescent Sensors Based on Terpyridine, Benzoxazole and Benzothiazole Chromophores." University of Akron / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=akron1512743963248758.

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Njaria, Paul Magutu. "Antimycobacterial 2-aminoquinazolinones and benzoxazole-based oximes: synthesis, biological evaluation, physicochemical profiling and supramolecular derivatization." Doctoral thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/26954.

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Tuberculosis (TB) is a life-threatening infectious disease caused by Mycobacterium tuberculosis (Mtb). Globally, TB is a major public health burden with an estimated 10.4 million new cases and 1.8 million deaths reported in 2015. Although TB is curable, the treatment options currently available are beset by numerous shortcomings such as lengthy and complex treatment regimens, drug-drug interactions, drug toxicities, as well as emergence of widespread multi-drug resistance. Therefore, there is an urgent and compelling need to develop new, more effective, safer drugs with novel mechanisms of act
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de, Souza Lucio R. "SYNTHESIS AND APPLICATION OFHIGH PERFORMANCE BENZOXAZINE-EPOXY COPOLYMERS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1618528984888642.

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Hutson, Leslie K. "Synthesis of Benzoxazoles Containing Allyl Crosslinking Sites via Claisen Rearrangements." Wright State University / OhioLINK, 1999. http://rave.ohiolink.edu/etdc/view?acc_num=wright974400715.

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Demachy, Charles. "Synthèse électrochimique de nouveaux dérivés de la benzoxazine." Paris 5, 1995. http://www.theses.fr/1995PA05P068.

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Pham, Hong-Ngoc. "Synthesis of enantiopure 3,4-dihydro-2H-1,4-benzoxazine analogues for potential biological applications." Electronic Thesis or Diss., Université de Lorraine, 2020. http://www.theses.fr/2020LORR0186.

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Ce travail décrit la synthèse et l'analyse conformationnelle de pseudodipeptides et pseudotripeptides à base d’un motif 1,4-benzoxazinique énantiopur. Les énantiomères du 2,3-dibromopropionate d'éthyle et du 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate d'éthyle sont obtenus par deux stratégies (i) synthèse énantiosélective et (ii) énantioséparation des racemiques par HPLC préparative à l’échelle du multigramme. En raison de processus de racémisation au cours des synthèses énantiosélectives, l'énantioséparation des racemiques par HPLC préparative est realisée avec succès pour accéder aux différ
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Liu, Jingping. "Synthesis, characterization, reaction mechanism and kinetics of 3,4-dihydro-2H-1,3-benzoxazine and its polymer." Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1062775094.

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Books on the topic "Benzoxazole – Synthesis"

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Handbook of benzoxazine resins. Elsevier, 2011.

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Book chapters on the topic "Benzoxazole – Synthesis"

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Neelima, G., K. Lakshmi, and K. Sesha Maheswaramma. "In Silico Studies of Benzoxazole Derivatives Using Ferrite-L-cysteine Magnetic Nanoparticles: Green Synthesis." In Special Publications. Royal Society of Chemistry, 2019. http://dx.doi.org/10.1039/9781839160783-00288.

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Wang, Fengjiang, and James R. Hauske. "Solid-Phase Synthesis of Benzoxazoles via Mitsunobu Reaction." In Solid-Phase Organic Syntheses. John Wiley & Sons, Inc., 2001. http://dx.doi.org/10.1002/0471220434.ch7.

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Singhal, Manisha, and Vinay Prabha Sharma. "Synthesis and Medicinal Importance of Benzoxazine, Benzoxazinone and Their Derivatives: A Short Review." In Springer Proceedings in Earth and Environmental Sciences. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79065-3_2.

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Kantlehner, W. "Synthesis from Benzoxazole-2-thiones." In Three Carbon-Heteroatom Bonds: Ketenes and Derivatives. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-024-00421.

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List, B., C. Chandler, R. R. Torres, and A. Erkkilä. "Synthesis from 2-(Methylsulfanyl)benzoxazole." In X-Ene-X (X=F, Cl, Br, I, O, S, Se, Te, N, P), Ene-Hal, and Ene-O Compounds. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-032-00279.

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Schnrch, M., J. Hmmerle, and P. Stanetty. "Synthesis of Benzoxazole-2(3)-thiones." In Science of Synthesis Knowledge Updates KU 2011/1. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-111-00428.

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Schnrch, M., J. Hmmerle, and P. Stanetty. "Chlorination of Benzoxazole-2(3)-thiones." In Science of Synthesis Knowledge Updates KU 2011/1. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-111-00476.

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Schnrch, M., J. Hmmerle, and P. Stanetty. "Alkoxylation of Benzoxazole-2(3)-thiones." In Science of Synthesis Knowledge Updates KU 2010/4. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-111-00477.

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Schnrch, M., J. Hmmerle, and P. Stanetty. "Amination of Benzoxazole-2(3)-thiones." In Science of Synthesis Knowledge Updates KU 2011/1. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-111-00478.

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Schnrch, M., J. Hmmerle, and P. Stanetty. "S-Alkylation of Benzoxazole-2(3)-thiones." In Science of Synthesis Knowledge Updates KU 2010/4. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-111-00482.

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Conference papers on the topic "Benzoxazole – Synthesis"

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Affeldt, Ricardo F., Dennis Russowsky, and Fabiano S. Rodembusch. "Novel Photoactive N-Heterocycles Bearing a Benzoxazole Moiety: Synthesis and Photophysical study." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0156-1.

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Jampilek, Josef, Jarmila Vinsova, Tatjana Grafnetterova, and Jiri Dohnal. "Synthesis and Hydrophobic Properties of Benzoxazoles." In The 9th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2005. http://dx.doi.org/10.3390/ecsoc-9-01466.

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Ha, Sie-Tiong, and Kok-Leei Foo. "New thermotropic liquid crystals with benzoxazole core." In The 15th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2011. http://dx.doi.org/10.3390/ecsoc-15-00747.

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Vinšová, Jarmila, Václav Horák, Vladimír Buchta, and Jarmila Kaustová. "Highly Lipophilic Benzoxazoles with Potential Antibacterial Activity." In The 8th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2004. http://dx.doi.org/10.3390/ecsoc-8-01977.

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Soares, Ana, Susana Costa, and M. Sameiro Gonçalves. "Benzoxazole Derivatives as Phototriggers for the Release of Butyric Acid." In The 18th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2014. http://dx.doi.org/10.3390/ecsoc-18-a034.

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Seijas, Julio, M. Vázquez-Tato, M. Carballido-Reboredo, and José Crecente-Campo. "P2S5 Mediated Synthesis of Benzoxazoles and Benzothiazoles by Microwave Irradiation." In The 9th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2005. http://dx.doi.org/10.3390/ecsoc-9-01642.

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