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Journal articles on the topic '-(benzylideneamino)- 2'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Shrivastava, Shobhit, and Dharmendra Ahuja. "Synthesis, Characterization and Antimicrobial Activity of Some Novel Mannich Bases of Indole-2,3-dione." Asian Journal of Chemistry 35, no. 5 (2023): 1183–88. http://dx.doi.org/10.14233/ajchem.2023.27738.

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Indole-2,3-dione (isatin) and its 5-substituted derivatives have been reacted with N2-benzylidenepyridine-2,6-diamine to form Schiff bases and the Mannich bases of these compounds were synthesized by reacting them with some secondary amines in presence of formaldehyde. Their chemical structures have been confirmed by mean of their IR and 1H NMR. Antimicrobial screening of synthesized compounds was done by well diffusion method against 4 pathogenic bacteria and 2 pathogenic fungi. Amongst the tested compounds 3-{[6-(benzylideneamino)pyridin-2-yl]imino}-1- (piperazin-1-ylmethyl)-5-fluoro-indolin

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2

Wang, Yong, Shanshan Shi, Yanhua Han, and Guo-Dong Wei. "Bis[2-(benzylideneamino)phenyl] disulfide." Acta Crystallographica Section E Structure Reports Online 67, no. 12 (2011): o3364. http://dx.doi.org/10.1107/s1600536811048239.

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3

Khan, Muhammad Naeem, Misbahul Ain Khan, Noreen Aslam, Pir Bakhsh Khan, and Ehsan ul Haq. "Tetracyclic Heteroaromatic Systems-Synthesis of Ethoxycarbonylphenylpyrido[3',2':5,6] Thiopyranoquinolines." Pakistan Journal of Scientific & Industrial Research Series A: Physical Sciences 64, no. 3 (2021): 191–94. http://dx.doi.org/10.52763/pjsir.phys.sci.64.3.2021.191.194.

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7-benzylideneamino-5H-thiochromeno[2,3-b]pyridin-5-ones and 9-benzylideneamino-5H-thio- chromeno[2,3-b]pyridin-5-ones, on reaction with ethyl pyruvate to afford 1-ethoxycarbonyl-3-phenyl-12H- pyrido[3',2':5,6]thiopyrano[3,2-f]quinoline-12-ones and 4-ethoxycarbonyl-2-phenyl-7H- pyrido[3',2':5,6]thiopyrano[3,2-h]quinoline-7-ones respectively by the two different methods. These products were precipitated by addition of ethanol, water (1:1), were purified by recrystalizing from appropriate solvents and were characterized from their IR, 1H-NMR, mass spectra and elemental analysis data.

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4

Varsha, G., V. Arun, Manju Sebastian, P. Leeju, Digna Varghese, and K. K. M. Yusuff. "(Z)-2-Amino-3-[(E)-benzylideneamino]but-2-enedinitrile." Acta Crystallographica Section E Structure Reports Online 65, no. 4 (2009): o919. http://dx.doi.org/10.1107/s1600536809010873.

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5

Karadağ, Aslı Tosyalı, Şehriman Atalay, and Hasan Genç. "2-[(E)-2-Hydroxy-5-(trifluoromethoxy)benzylideneamino]-4-methylphenol." Acta Crystallographica Section E Structure Reports Online 67, no. 1 (2010): o95. http://dx.doi.org/10.1107/s1600536810050579.

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6

Khlebnikov, A. F., E. I. Kostik, and R. R. Kostikov. "Reaction of dihalocarbenes with 2-(benzylideneamino)pyridines. Cyclization of 2-(benzylideneamino)pyridinium dihalomethylids to give 2-aryl-3-haloimidazo[1,2-?]pyridines." Chemistry of Heterocyclic Compounds 27, no. 6 (1991): 636–42. http://dx.doi.org/10.1007/bf00472515.

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7

Vennila, M., G. Manikandan, V. Thanikachalam, and J. Jayabharathi. "Non-Isothermal Decomposition of 2-(2-Hydroxybenzylideneamino)-3-phenylpropanoic Acid in Nitrogen Atmosphere." E-Journal of Chemistry 8, no. 2 (2011): 819–29. http://dx.doi.org/10.1155/2011/235090.

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The non-isothermal decomposition properties of 2-(2-hydroxy- benzylideneamino)-3-phenylpropanoic acid [HBAPPA] have been studied using microanalysis, FT-IR, UV, DTA, DTG and TG techniques. The TG studies were carried out at different heating rates of 10, 15 and 20 K/min. The Schiff base decomposed in three stages. The kinetic parameters were deduced for each stage. A probable mechanism has been proposed for the decomposition process.

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8

Deohate, Pradip P., and Roshani S. Mulani. "Microwave Irradiative Synthesis of Triazine Substituted Pyrazoles and Study of Antitubercular and Antimicrobial Activities." Asian Journal of Chemistry 31, no. 5 (2019): 1087–90. http://dx.doi.org/10.14233/ajchem.2019.21826.

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Microwave irradiative synthesis of triazine substituted pyrazoles i.e. (4-benzylideneamino-6-methyl-[1,3,5]-triazin-2-yl)-(5-methyl-2-substituted benzoyl/isonicotinoyl/cinnamoyl-pyrazol-3-yl)-amines have been achieved by the cyclocondensation of N-(4-benzylideneamino-6-methyl-[1,3,5]-triazin-2-yl)-3-oxo butyramide with substituted acid hydrazides. Synthesis of required butyramide was done by reacting 2,4-diamino-6-methyl-[1,3,5]-triazine with benzaldehyde and then condensing the product with ethyl acetoacetate. Structural investigation of synthesized compounds has been done by chemical transfo

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9

Akerman, Matthew P., and Sarah J. Maher. "(E)-2,3-Bis[(E)-benzylideneamino]but-2-enedinitrile." Acta Crystallographica Section E Structure Reports Online 68, no. 3 (2012): o688. http://dx.doi.org/10.1107/s1600536812005363.

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10

Balcázar, J. L., F. Florencio та S. García-Blanco. "Structure of 2-[α-(methylthio)benzylideneamino]-2-phenyl-1,1-ethylenedicarbonitrile". Acta Crystallographica Section C Crystal Structure Communications 41, № 12 (1985): 1795–97. http://dx.doi.org/10.1107/s0108270185009490.

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11

G., Bhargavi, Sireesha B., and Sarala Devi Ch. "A study on potential donor sites of some substituted 1,2,4-triazoles and their denticity." Journal of Indian Chemical Society Vol. 79, Oct 2002 (2002): 826–27. https://doi.org/10.5281/zenodo.5847784.

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Department of Chemistry, University College for Women, Osmania University, Hyderabad-500 195, India <em>E-mail : </em>dr_saraladevich@yahoo.com <em>Manuscript received 20 November 2001, revised 3 May 2002. accepted 17 June 2002</em> 4-Amino-5-(2'-hydroxy)pheny1-3-mercapto-1,2,4-triazole (AHPMT) and its Schiff bases, viz. 4-benzylideneamino-5-(2'-hydroxy)pheny1- 3-mercapto-1,2,4-triazole (BHPMT) and 4-(2'-hydroxy)benzylideneamino-5-(2'-hydroxy)pheny1-3-mercapto-1,2,4-triazole (HBHPMT) were synthesized. Proton-ligand and metal(ii)-ligand constants (M = Co, Ni, Zn and Pb) of

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12

Mironov, V. F., T. A. Baronova, M. N. Dimukhametov, R. Z. Musin, L. M. Abdrakhmanova, and A. I. Konovalov. "Reaction of 2-[2-(Benzylideneamino)phenoxy]-and 2-[2-(Benzylideneamino)ethoxy]-1,3,2-benzodioxaphospholes with hexafluoroacetone. Formation of spirophosphoranes with phosphorus-carbon and phosphorus-nitrogen bonds." Russian Journal of General Chemistry 76, no. 3 (2006): 490–92. http://dx.doi.org/10.1134/s1070363206030224.

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13

Widiyana, Anita Puspa. "COMPUTATION DESIGN OF QUINAZOLINE-4(3H)-ON DERIVATIVES AS CYCLOOXYGENASE-2 (COX-2) INHIBITOR." Jurnal Farmasi Sains dan Praktis 7, no. 2 (2021): 163–70. http://dx.doi.org/10.31603/pharmacy.v7i2.4827.

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    The 3-(benzylideneamino)-2-(2,4-dichlorophenyl)-quinazoline-4(3H)-ones (BDCQ) are compounds developed as anticancer drugs and quinazolines. The activity and bioavailability of BDCQ derivatives as anticancer compounds that inhibit COX-2 can be predicted by computer programs and online servers. Substituents are added at positions 2 and 3 to the quinazoline-4(3H)-on ring, such as -H, -NO2, -OCH3, -N(CH3)2, -SO2NH2, -OH, and –OCH3. QSAR as COX-2 inhibitor analysis was performed by SPSS Ver. 21 software. Lipinski’s rule of five for determining bioavailability is performe

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14

Yin, Weiyan, Zhi Wang, and Zi-Wen Yang. "5-({[(E)-Benzylideneamino]oxy}methyl)-1,3,4-thiadiazol-2-amine." Acta Crystallographica Section E Structure Reports Online 68, no. 3 (2012): o769. http://dx.doi.org/10.1107/s1600536812003893.

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15

Kumaradhas, P., G. Sankara Lakshmi, B. Sridhar, P. Paneer Selvam, and G. Saravanan. "3-[4-(Dimethylamino)benzylideneamino]-2-methylquinazolin-4(3H)-one." Acta Crystallographica Section E Structure Reports Online 63, no. 11 (2007): o4293. http://dx.doi.org/10.1107/s1600536807047393.

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In the title compound, C18H18N4O, the dihedral angle between the quinazoline and benzylidene groups is 54.0 (4)°. In the crystal structure, the molecules associate into centrosymmetric dimers via C—H...O interactions.

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16

Merugu, Shivanand, Vijaya Kumar Ponnamaneni, Ravi Varala, et al. "Metal-free Catalyzed One-Pot Multicomponent Synthesis of (E)-3-(2-((5-(Benzylideneamino)-1,3,4-thiadiazol-2-yl)thio) Acetyl)-2H-chromen-2-one Derivatives and Their Biological Evaluation." Journal of Chemistry 2020 (April 10, 2020): 1–7. http://dx.doi.org/10.1155/2020/4869279.

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A series of (E)-3-(2-((5-(benzylideneamino)-1,3,4-thiadiazol-2-yl)thio) acetyl)-2H-chromen-2-one and its derivatives (4a-h) have been obtained using a one-pot multicomponent reaction with good yields. The compounds have been synthesized from 3-(2-bromoacetyl)chromen-2-ones (1), 5-amino-1,3,4-thiadiazole-2-thiol (2), and substituted benzaldehydes (3) in anhydrous ethanol and conc. H2SO4. Subsequently, all the synthesized compounds have been screened for their antimicrobial activity and characterized by analytical and spectral data.

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17

Rivera, Augusto, Ingrid Miranda-Carvajal, Jaime Ríos-Motta, and Michael Bolte. "Crystal structure of 1,3-bis[(E)-benzylideneamino]propan-2-ol." Acta Crystallographica Section E Crystallographic Communications 73, no. 4 (2017): 627–29. http://dx.doi.org/10.1107/s2056989017004741.

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In the title compound, C17H18N2O, the central carbon atom with the OH substituent and one of the (E)-benzylideneamino substituents are disordered over two sets of sites with occupancies of 0.851 (4) and 0.149 (4). The relative positions of the two disorder components is equivalent to a rotation of approximately 60° about the C—N single bond. In the crystal, the molecules are held together by O—H...N hydrogen bonds, forming simpleC(5) chains along theb-axis direction. In addition, pairs of the chains are further aggregated by weak C—H...π interactions.

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18

YILMAZ, Zehra Kübra, Belma ASIM, and Ozlem OZDEMIR. "In vitro antioxidant properties of 2-(4-(2-hydroxybenzylideneamino)benzylideneamino)benzoic acid." ICONTECH INTERNATIONAL JOURNAL 5, no. 3 (2021): 7–12. http://dx.doi.org/10.46291/icontechvol5iss3pp7-12.

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In recent years, it has attracted great attention to determine and appraise synthetic antioxidants with high free radical scavenging capacity associated with various disorders. Because synthetic antioxidants are widely used in place of native antioxidants as they are influential and less expensive. In this study, the antioxidant activity of the newly synthesized asymmetric diimine Schiff base was determined by using DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging, ferrous ion chelation (FIC) activity and total antioxidant activity (Phosphomolybdenum assay) methods. The effective concen

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19

Vasu, K. A. Nirmala, Deepak Chopra, S. Mohan, and J. Saravanan. "2-[(E)-Benzylideneamino]-N-(2-fluorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide." Acta Crystallographica Section E Structure Reports Online 61, no. 2 (2005): o236—o238. http://dx.doi.org/10.1107/s1600536804033008.

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20

Huang, Yuan, Yaru Qin, Yu Ge, et al. "Rationally assembled nonanuclear lanthanide clusters: Dy9 displays slow relaxation of magnetization and Tb9 serves as luminescent sensor for Fe3+, CrO42− and Cr2O72−." New Journal of Chemistry 43, no. 48 (2019): 19344–54. http://dx.doi.org/10.1039/c9nj04893f.

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The utilization of a Schiff base ligand 2-((2-hydroxy-4-methoxy-benzylideneamino)methyl)phenol (H<sub>2</sub>L) afforded five nonanuclear lanthanide(iii) clusters. Dy<sub>9</sub> displays slow relaxation of magnetization and Tb<sub>9</sub> serves as luminescent sensor for Fe<sup>3+</sup>, CrO<sub>4</sub><sup>2−</sup> and Cr<sub>2</sub>O<sub>7</sub><sup>2−</sup>.

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21

Kaur, Manpreet, Jerry P. Jasinski, Channappa N. Kavitha, Hemmige S. Yathirajan, and K. Byrappa. "[2-(Benzylideneamino)-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl](phenyl)methanone." Acta Crystallographica Section E Structure Reports Online 70, no. 5 (2014): o507—o508. http://dx.doi.org/10.1107/s1600536814006679.

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In the title compound, C22H19NOS, the cyclohexene ring of the tetrahydrobenzothiophenyl ring system adopts a slightly distorted half-chair conformation and is twisted slightly [7.5 (8)° for the major disorder component] from the mean plane of the thiophene ring. The dihedral angles between the mean planes of the thiophene ring and the phenyl rings are 65.7 (3) and 8.3 (4)°. The phenyl rings are twisted with respect to each other by 73.8 (7)°. Disorder was modeled for four C atoms of the cyclohexene ring over two sets of sites with an occupancy ratio of 0.659 (2):0.341 (2). In the crystal, a si

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22

Takabayashi, Yutaka, Takeshi Yusa, Masahiro Minabe, Takao Kimura, and Motohiro Tsubota. "Liquid Crystallinity of 2-Acyl-7-[p-(alkoxy)benzylideneamino]fluorenes." Bulletin of the Chemical Society of Japan 72, no. 12 (1999): 2755–60. http://dx.doi.org/10.1246/bcsj.72.2755.

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23

D.K. Gautam and I. Singh. "A NEW SERIES OF 1,3,4-THIADIAZOLE SUBSTITUTED AZETIDINONE AND THIAZOLIDINONE DERIVATIVES AND THEIR ANTIMICROBIAL ACTIVITY." RASAYAN Journal of Chemistry 17, no. 01 (2024): 176–82. http://dx.doi.org/10.31788/rjc.2024.1718308.

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The new series of 2-({[5-(3-chloro-2-oxo-4-substituted-phenylazetidin-1-yl)-1,3,4-thiadiazol-2- yl]methyl}amino)benzoic acid (13-20) and 2-({[5-(4-oxo-2- substituted-phenyl-1,3-thiazolidin-3-yl)- 1,3,4- thiadiazol-2-yl]methyl}amino)benzoic acid (21-28) have been synthesized from 2-[({5-[(benzylideneamino]- 1,3,4- thiadiazol-2-yl }methyl)amino]-benzoic acid (5-12). All these synthesized compounds were tested for their antimicrobial activity and established by spectroscopic data, and elemental analyses.

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24

Yan, Guo-Bing, Chun-Niu Zhang, and Ming-Hua Yang. "1,5-Dimethyl-4-[2-(methylsulfanyl)benzylideneamino]-2-phenyl-1H-pyrazol-3(2H)-one." Acta Crystallographica Section E Structure Reports Online 63, no. 5 (2007): o2663—o2664. http://dx.doi.org/10.1107/s1600536807007453.

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25

Hunas hala, Rajesh, Pradeepkumar Ronad, Veeresh Maddi, Satyanarayana Darbhamulla, and Mohammad Kamdod. "Synthesis and Biological Activities of N’-[4-(substituted benzylideneamino)-3- (2′,4′-dichlorophenoxymethyl)-1,2,4-triazol-5yl)] isonicotinyl hydrazides." International Journal of Drug Design and Discovery 1, no. 2 (2010): 107–13. https://doi.org/10.37285/ijddd.1.2.1.

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N'-[4-(substituted benzylideneamino)-3-(2′,4′-dichlorophenoxymethyl)-1,2,4-triazol-5yl)] isonicotinyl hydrazide derivatives have been synthesized by the reaction between N′ -[4-amino-3-(2′,4′-dichlorophenoxymethyl)-1,2,4-triazol-5yl] isonicotinyl hydrazide and various aromatic aldehydes in presence catalytic amount of hydrochloric acid in alcohol. All these compounds were screened for antibacterial, antifungal and antitubercular activity. The compounds 3b and 3j exhibited more potent antifungal activity against A. niger, and A. fumigatus at MIC of 0.25 µg/mL.

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26

Fernández-Lodeiro, Javier, Cristina Núñez, Emilia Bértolo, José Capelo, and Carlos Lodeiro. "N1-Benzylidene-N2-(2-((2-((2-(benzylideneamino)ethyl)amino) ethyl)amino)ethyl)ethane-1,2-diamine." Molbank 2012, no. 4 (2012): M779. http://dx.doi.org/10.3390/m779.

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27

AYTEMIZ, Fevzi, Murat BEYTUR, and Haydar YUKSEK. "Experimentical and Gaussian Calculations of 3-Ethyl-4-(2-Benzenesulfonyloxy)-Benzylideneamino-4,5-Dihydro-1H-1,2,4-Triazol-5-One." Eurasia Proceedings of Science Technology Engineering and Mathematics 20 (December 21, 2022): 103–11. http://dx.doi.org/10.55549/epstem.1222658.

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3-Ethyl-4-(2-benzenesulfonyloxy)-benzylideneamino-4,5-dihydro-1H-1,2,4-triazol-5-one has been optimized using the DFT/B3LYP and B3PW91 methods with the 6-311G(d,p) basis set in the ground state. The vibrational (IR) frequencies, 1H and 13C NMR chemical shift values (in gas phase and in DMSO solvent), nonlinear optical properties (NLO), HOMO−LUMO analysis and molecular electrostatic potential surfaces of 3-Ethyl-4-(2-benzenesulfonyloxy)-benzylideneamino-4,5-dihydro-1H-1,2,4-triazol-5-one have been calculated using the DFT/B3LYP and DFT/B3PW91 methods with the 6-311G(d,p) basis set. IR absorptio

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28

Bruno, Giuseppe, Francesco Nicoló, Fausto Puntoriero, Gaetano Giuffrida, Vittorio Ricevuto, and Giuseppe Rosace. "4-[4-(Dimethylamino)benzylideneamino]-3,5-bis(2-pyridyl)-4H-1,2,4-triazole." Acta Crystallographica Section C Crystal Structure Communications 59, no. 7 (2003): o390—o391. http://dx.doi.org/10.1107/s0108270103011697.

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29

Jian, Fang-Fang, Xiao-Yan Ren, Yong-Qi Qin, and Li-Hong Hu. "4-(Benzylideneamino)-3-(2-pyridyl)-1H-1,2,4-triazole-5(4H)-thione." Acta Crystallographica Section E Structure Reports Online 63, no. 7 (2007): o3056. http://dx.doi.org/10.1107/s1600536807025573.

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30

Gasparto, Alan Kiill, Ludmila Matos Baltazar, Ludmila Ferreira Gouveia, et al. "2-(Benzylideneamino)phenol: A Promising Hydroxyaldimine with Potent Activity Against Dermatophytoses." Mycopathologia 179, no. 3-4 (2014): 243–51. http://dx.doi.org/10.1007/s11046-014-9850-5.

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31

Gaucher, Anne, Jean Ollivier, Jacqueline Marguerite, Renée Paugam, and Jacques Salaün. "Total asymmetric syntheses of (1S,2S)-norcoronamic acid, and of (1R,2R)- and (1S,2S)-coronamic acids from the diastereoselective cyclization of 2-(N-benzylideneamino)-4-chlorobutyronitriles." Canadian Journal of Chemistry 72, no. 5 (1994): 1312–27. http://dx.doi.org/10.1139/v94-164.

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(3R)-2-(N-Benzylideneamino)-4-chloro-3-methylbutyronitrile 3, prepared from the commercially available methyl (2S)-3-hydroxy-2-methyl propionate 5 (96% ee), readily underwent potassium carbonate induced cyclization to provide, after acid hydrolysis (6 N HCl) and chromatography, the (1S,2S)-norcoronamic acid 1a with 88% diastereoselectivity and > 95% enantiomeric excess. From (2R)-2-(hydroxymethyl)butyl acetate 23 (> 88% ee) obtained by enzymatic enantioselective hydrolysis with lipase PS, was prepared the (3S)-2-(N-benzylideneamino)-3-(chloromethyl)valeronitrile 29, which after base-indu

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32

Diao, Chun-Hua, and Xin Chen. "(E)-1,5-Dimethyl-4-{2-[2-(2-nitrophenoxy)ethoxy]benzylideneamino}-2-phenyl-1H-pyrazol-3(2H)-one." Acta Crystallographica Section E Structure Reports Online 62, no. 10 (2006): o4422—o4424. http://dx.doi.org/10.1107/s1600536806036269.

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33

Laus, Gerhard, Volker Kahlenberg, Klaus Wurst, Thomas Müller, Holger Kopacka, and Herwig Schottenberger. "Synthesis and Crystal Structures of New 1,3-Disubstituted Imidazoline-2-thiones." Zeitschrift für Naturforschung B 68, no. 11 (2013): 1239–52. http://dx.doi.org/10.5560/znb.2013-3184.

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Two methods (MeOH/K2CO3, pyridine/Et3N) were assessed for the introduction of sulfur into the 2-position of 1,3-disubstituted quaternary imidazolium salts 1-9 (Cl, I, BF4, PF6, CH3OSO3 were used as anions) to yield nine 1,3-disubstituted imidazoline-2-thiones 10-18 (1, 10: R1 = CH3, R2 = CH3; 2, 11: R1 = OCH2Ph, R2 = CH3; 3, 12: R1 = OCH3, R2 = CH3; 4, 13: R1 = OCH3, R2 = OCH3; 5, 14: R1 = NH2, R2 = CH2Ph; 6, 15: R1 = NCHPh, R2 = CH3; 7, 16: R1 = NH2, R2 = CH3; 8, 17: R1 = NCHPh, R2 = NCHPh; 9, 18: R1 = NH2, R2 = OCH3). Compounds 11-18 represent N-alkyloxy and N-amino imidazoline-2-thiones, wh

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34

Elaas, Nibras Ahmed, Danfeng Huang, Ke-Hu Wang, Yingpeng Su, and Yulai Hu. "Tin powder-promoted allylation and cyclization of 2-(benzylideneamino)isoindoline-1,3-diones." Heterocyclic Communications 24, no. 3 (2018): 159–63. http://dx.doi.org/10.1515/hc-2017-0249.

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Abstractα-Methylene-γ-lactams were synthesized from readily available N-acylhydrazones by a tin-mediated Barbier-type reaction. The method avoids the use of toxic allylstannanes and the reaction proceeds smoothly under mild conditions.

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35

Harrison, William T. A., H. J. Ravindra, M. R. Suresh Kumar, and S. M. Dharmaprakash. "(2E)-1-{4-[(1E)-Benzylideneamino]phenyl}-3-phenylprop-2-en-1-one." Acta Crystallographica Section E Structure Reports Online 63, no. 12 (2007): o4675. http://dx.doi.org/10.1107/s160053680705684x.

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36

Takabayashi, Yutaka, Takeshi Yusa, Masahiro Minabe, Takao Kimura, and Motohiro Tsubota. "ChemInform Abstract: Liquid Crystallinity of 2-Acyl-7-[p-(alkoxy)benzylideneamino]fluorenes." ChemInform 31, no. 13 (2010): no. http://dx.doi.org/10.1002/chin.200013069.

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37

Wei, Zhen, Xujun Zheng, Junjun Bai, Xiaohong Zhai, and Lili Song. "2-[(E)-2-(Benzylideneamino)ethyl]-3′,6′-bis(diethylamino)spiro[isoindoline-1,9′-xanthen]-3-one." Acta Crystallographica Section E Structure Reports Online 67, no. 7 (2011): o1733. http://dx.doi.org/10.1107/s1600536811020320.

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38

Diao, Chun-Hua, and Ming Yu. "(E)-1,5-Dimethyl-4-[3-(2-phenoxyethoxy)benzylideneamino]-2-phenyl-1H-pyrazol-3(2H)-one." Acta Crystallographica Section E Structure Reports Online 62, no. 10 (2006): o4658—o4659. http://dx.doi.org/10.1107/s1600536806038402.

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39

Zhang, Qiao-Zhen, Yan-Li Zhao, Xin Chen, and Ming Yu. "(E)-4-[2-(4-Chlorobenzyloxy)benzylideneamino]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one." Acta Crystallographica Section E Structure Reports Online 62, no. 11 (2006): o5252—o5254. http://dx.doi.org/10.1107/s1600536806043625.

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J. Abdulghani, Prof Dr Ahlam, and Rasha Kudher Hussain. "SYNTHESIS AND CHARACTERIZATION OFGOLDNANOPARTICLESUSING CEFOTAXIMSODIUM AND ITS SCHIFF BASE DERIVATIVE WITH 4-N,N-DIMETHYLAMINO BENSALDEHYDEAS REDUCING ANDSTABILIZING AGENTS." JOURNAL OF ADVANCES IN CHEMISTRY 11, no. 8 (2015): 3838–49. http://dx.doi.org/10.24297/jac.v11i8.2190.

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Conjugated GNPs were synthesized by one step reaction of AuCl4- with cefotaxim (CFX) and its Schiff base derivative with 4-N,N-dimethylamino benzaldehyde [sodium 3-(acetoxymethyl)-7-((2Z)-2-(2-(4-dimethylamino) benzylideneamino) thiazol-4-yl)-2-(methoxyimino) acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] (SCFX)without the need of reducing and functionalizing agents. The reduction process was monitored by uv-visible spectrophotometry and the synthesized GNPs were characterized by TEM, SEM, AFM and XRD analysis. The conjugation of GNPs with the two ligands was characterized

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41

Wang, Qiang, та Daqi Wang. "Di-μ-chlorido-bis(chlorido{2-[4-(dimethylamino)benzylideneamino]pyridine-κN}mercury(II))". Acta Crystallographica Section E Structure Reports Online 63, № 8 (2007): m2074. http://dx.doi.org/10.1107/s1600536807032047.

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42

Balcazar, J. L., F. Florencio та S. García-Blanco. "Structure of methyl (Z)-2-cyano-3-[(E)-α-(methylthio)benzylideneamino]-3-phenylpropenoate". Acta Crystallographica Section C Crystal Structure Communications 43, № 7 (1987): 1438–40. http://dx.doi.org/10.1107/s0108270187091534.

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43

Taile, V. S., V. N. Ingle, and K. M. Hatzade. "Synthesis of 2-(Substituted Benzylideneamino)-4-(4′-hydroxyphenyl) Thiazoles and Their O-Glucosides." Journal of Carbohydrate Chemistry 29, no. 5 (2010): 207–21. http://dx.doi.org/10.1080/07328303.2010.497589.

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44

Thilagavathi, R., Helen Kavitha, R. Arulmozhi, and Sunil Manohar Babu. "Synthesis of 3-{4-[4-(Benzylideneamino)benzenesulfonyl]- phenyl}-2-phenylquinazolin-4(3H)-one." Molbank 2009, no. 1 (2009): M589. http://dx.doi.org/10.3390/m589.

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Iwasaki, Fujiko, Joseph H. Yoshikawa, Hajime Yamamoto, et al. "TEMPO radicals showing magnetic interactions. II. 4-(Benzylideneamino)-TEMPO and related compounds." Acta Crystallographica Section B Structural Science 55, no. 6 (1999): 1057–67. http://dx.doi.org/10.1107/s0108768199007326.

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X-ray crystal structure analyses were performed on 4-(Ar-methyleneamino)-TEMPO radicals at room temperature (TEMPO = 2,2,6,6-tetramethylpiperidyl-1-oxyl): Ar = Ph [4-(benzylideneamino)-2,2,6,6-tetramethylpiperidyl-1-oxyl], 4-MeS-Ph [2,2,6,6-tetramethyl-4-(4-methylthiobenzylideneamino)piperidyl-1-oxyl], 4-Me-Ph [4-(4-methylbenzylideneamino)-2,2,6,6-tetramethylpiperidyl-1-oxyl], 4-PhO-Ph [2,2,6,6-tetramethyl-4-(4-phenoxybenzylideneamino)piperidyl-1-oxyl], 4-MeSO_{2}-Ph [2,2,6,6-tetramethyl-4-(4-methylsulfonylbenzylideneamino)piperidyl-1-oxyl], 3-Py [2,2,6,6-tetramethyl-4-(3-pyridylmethylideneami

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46

Thirunarayanan, Ganesamoorthy, and K. G. Sekar. "Solvent-Free Synthesis and Spectral Linearity of Some (E)-2-(substituted benzylideneamino)-N-(3-chloro-4-fluorophenyl)-hexahydro-2H-cyclopenta[b]thiophene-3-carboxamides." International Letters of Chemistry, Physics and Astronomy 13 (September 2013): 160–74. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.13.160.

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Some (E)-2-(substituted benzylideneamino)-N-(3-chloro-4-fluorophenyl)-hexahydro-2H-cyclopenta[b]thiophene-3-carboxamide derivatives have been synthesized by SiO2:H3PO4 catalyzed solvent-free condensation of 2-amino-N-(3-chloro-4-fluorophenyl)-hexahydro-2H-cyclopenta [b]thiophene-3-carboxamide and various substituted benzaldehydes in microwave irradiation. The yield of the imine-carboximido derivatives has been found to be more than 85 %. The purity of all imine-carboximido derivatives has been checked using their physical constants and spectral data. The spectral data of the imine-carboximido

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47

Laus, Gerhard, Klaus Wurst, Alexander Schwärzler, Günther Bonn, and Herwig Schottenberger. "Crystal structure of bis(1-benzylideneamino-3-ethylimidazolin-2-ylidene)- silver(I) hexafluorophosphate, [Ag(C12H13N3)2][PF6]." Zeitschrift für Kristallographie - New Crystal Structures 223, no. 3 (2008): 213–14. http://dx.doi.org/10.1524/ncrs.2008.0089.

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48

Zhang, Wen-Jun, Zhong-Yu Duan, and Xin Zhao. "(E)-4-[3-Ethoxy-4-(2-phenoxyethoxy)benzylideneamino]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one." Acta Crystallographica Section E Structure Reports Online 62, no. 7 (2006): o2963—o2964. http://dx.doi.org/10.1107/s160053680602304x.

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The title compound, C28H29N3O4, was prepared by the reaction of 4-amino-1,5-dimethyl-2-phenylpyrazol-3-one and 3-ethoxy-4-(2-phenoxyethoxy)benzaldehyde. The vanillin group makes dihedral angles of 73.08 (8) and 66.54 (6)° with the planes of the two terminal phenyl rings, and an angle of 30.49 (6)° with the pyrazolone ring plane. The crystal structure is stabilized by intermolecular C—H...O hydrogen bonds that form centrosymmetric dimers.

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Lin, Shwu-Jiuan, Wei-Jern Tsai, Wen-Fei Chiou, Tsang-Hsiung Yang, and Li-Ming Yang. "Selective COX-2 inhibitors. Part 2: Synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides." Bioorganic & Medicinal Chemistry 16, no. 5 (2008): 2697–706. http://dx.doi.org/10.1016/j.bmc.2007.11.033.

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John, Franklin, Jinu George, Mrinal Srivastava, et al. "Pluronic copolymer encapsulated SCR7 as a potential anticancer agent." Faraday Discussions 177 (2015): 155–61. http://dx.doi.org/10.1039/c4fd00176a.

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Nonhomologous end joining (NHEJ) of DNA double strand breaks (DSBs) inside cells can be selectively inhibited by 5,6-bis-(benzylideneamino)-2-mercaptopyrimidin-4-ol (SCR7) which possesses anticancer properties. The hydrophobicity of SCR7 decreases its bioavailability which is a major setback in the utilization of this compound as a therapeutic agent. In order to circumvent the drawback of SCR7, we prepared a polymer encapsulated form of SCR7. The physical interaction of SCR7 and Pluronic® copolymer is evident from different analytical techniques. The in vitro cytotoxicity of the drug formulati

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