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Relevant bibliographies by topics / Bepotastine

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Journal articles

Academic literature on the topic 'Bepotastine'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Bepotastine"

1

Malahat, Amatur R., Sudhakar Kodudula, and Vijaya L. Gali. "A prospective comparative study to evaluate the efficacy and safety of olopatadine eye drops and bepotastine eye drops in subjects of vernal kerato conjunctivitis." International Journal of Basic & Clinical Pharmacology 9, no. 5 (2020): 706. http://dx.doi.org/10.18203/2319-2003.ijbcp20201743.

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Background: Vernal keratoconjunctivitis (VKC) is an allergic eye disease that especially affects young boys. Both olopatadine and bepotestine are dual acting drugs that provide rapid symptomatic relief coupled with the long-term disease-modifying benefit. The present study is conducted to compare the efficacy and safety of olopatadine eye drops and bepotastine eye drops in patients of vernal keratoconjunctivitis.Methods: A prospective, randomized, parallel-group, comparative study is conducted over a period of 4 weeks on paediatric patients with VKC. 50 patients are recruited and randomized in

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2

Lyseng-Williamson, Katherine A. "Oral Bepotastine." Drugs 70, no. 12 (2010): 1579–91. http://dx.doi.org/10.2165/11205880-000000000-00000.

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3

Prashant, Kumar, and Verma Anurag. "Comparative Research on the Effectiveness and Safety of LongActing Antihistamines in Allergic Conjunctivitis in Indian Patients: An RCT Trial." International Journal of Pharmaceutical and Clinical Research 13, no. 4 (2021): 181–87. https://doi.org/10.5281/zenodo.14201914.

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<strong>Aim:</strong> The aim of the present study was to compare the safety and efficacy of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2% and Bepotastine besilate 1.5% in allergic conjunctivitis. <strong>Methods:</strong> A total of 90 patients with mild or moderate allergic conjunctivitis were randomized into three groups with an allocation ratio of 1:1:1 using computer-generated random number sequence to receive topical anti-allergic medication for 14 days as Group 1: Topical 0.25% Alcaftadine eye drops OD, Group 2: Topical 0.2% Olopatadine eye drops OD and Group 3: Topic

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4

Mrinalini, C. Damle* and Shital P. Ghode. "STABILITY INDICATING CHROMATOGRAPHIC METHOD FOR ESTIMATION OF BEPOTASTINE BESILATE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 06 (2018): 5222–28. https://doi.org/10.5281/zenodo.1289735.

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A Simple, rapid, stability indicating HPTLC method has been developed for estimation of bepotastine besilate. HPTLC separation was carried out on Merck TLC aluminium sheets precoated with silica gel 60F254 using mobile phase as chloroform : methanol. Bepotastine besilate gave sharp peak at RF 0.53 ±0.03 at 225nm.calibration curve was linear in range 5-25ug/band for bepotastine besilate. Stress degradation study was carried out according to ICH guidelines Q1A (R2) and the method was validated as per ICH guideline.

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5

Damle, M. C., and K. K. Pardeshi. "Development of Analytical Method to Monitor Dissolution of Bepotastine Besilate Tablet." Journal of Drug Delivery and Therapeutics 9, no. 4 (2019): 251–56. http://dx.doi.org/10.22270/jddt.v9i4.3037.

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Bepotastine Besilate is an anti-histaminic drug and it is marketed as tablet of strength 10mg. In this study an attempt is made to monitor the dissolution of Bepotastine Besilate tablet. Dissolution study was done for marketed sample using phosphate buffer 6.8, phosphate buffer 4.5 and 0.1 N HCl as dissolution media. Samples were analysed using UV spectrophotometer, HPLC and HPTLC. Detection wavelength selected was 226nm. A chromatographic separation is achieved on a C18 column with a mobile phase consisting of acetonitrile, water with isocratic elution with flow rate 1ml/min. Solvents used fo

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6

Renuka, Ranjan Alok, and Kumar Sinha Ajay. "Comparative Assessment of Alcaftadine 0.25%, Olopatadine Hydrochloride 0.2% and Bepotastine Besilate 1.5% as AntiAllergic Conjunctivitis Agents." International Journal of Pharmaceutical and Clinical Research 13, no. 6 (2021): 412–19. https://doi.org/10.5281/zenodo.14218171.

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<strong>Aim:</strong> The aim of the present study to compare the safety and efficacy of Alcaftadine 0.25%, Olopatadine hydrochloride 0.2% and Bepotastine besilate 1.5% in allergic conjunctivitis. <strong>Methods: </strong>A total of 90 patients with mild or moderate allergic conjunctivitis were randomized into three groups with an allocation ratio of 1:1:1 using computer‑generated random number sequence to receive topical anti-allergic medication for 14 days as Group 1: Topical 0.25% Alcaftadine eye drops OD, Group 2: Topical 0.2% Olopatadine eye drops OD and Group 3: Topical 1

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7

Sudipto Chatterjee, Vijendra R, Soumyadeep Mahapatra, and Kiran Kumar L. "A comparative study of efficacy and tolerability of bepotastine besilate (1.5%) and olopatadine hydrochloride (0.1%) eye drops in allergic conjunctivitis in a tertiary care hospital of the southern part of India." Asian Journal of Medical Sciences 15, no. 10 (2024): 9–14. https://doi.org/10.71152/ajms.v15i10.4136.

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Background: Allergic conjunctivitis is increasing with the rise in the levels of allergens. Drug therapy is usually needed in addition to avoidance of general allergens to treat this condition. Both bepotastine besilate and olopatadine hydrochloride ophthalmic solutions are newer additions in the treatment of allergic conjunctivitis having dual properties of second-generation antihistaminics along with mast cell stabilizing activity. Aims and Objectives: The aim of the study was to compare the efficacy and tolerability of bepotastine besilate (1.5%) and olopatadine hydrochloride (0.1%) eye dro

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8

Sudipto Chatterjee, Vijendra R, Soumyadeep Mahapatra, and Kiran Kumar L. "A comparative study of efficacy and tolerability of bepotastine besilate (1.5%) and olopatadine hydrochloride (0.1%) eye drops in allergic conjunctivitis in a tertiary care hospital of the southern part of India." Asian Journal of Medical Sciences 15, no. 10 (2024): 9–14. http://dx.doi.org/10.3126/ajms.v15i10.67247.

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Abstract:

Background: Allergic conjunctivitis is increasing with the rise in the levels of allergens. Drug therapy is usually needed in addition to avoidance of general allergens to treat this condition. Both bepotastine besilate and olopatadine hydrochloride ophthalmic solutions are newer additions in the treatment of allergic conjunctivitis having dual properties of second-generation antihistaminics along with mast cell stabilizing activity. Aims and Objectives: The aim of the study was to compare the efficacy and tolerability of bepotastine besilate (1.5%) and olopatadine hydrochloride (0.1%) eye dro

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9

Kitaba, Shun, Hiroyuki Murota, Yoko Yahata, Hiroaki Azukizawa, and Ichiro Katayama. "Novel Functional Aspect of Antihistamines: The Impact of Bepotastine Besilate on Substance P-Induced Events." Journal of Allergy 2009 (June 21, 2009): 1–7. http://dx.doi.org/10.1155/2009/853687.

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Besides histamine, substance P (SP) has been demonstrated to play a crucial role in pruritic skin diseases. Although antihistamines are frequently used for pruritic skin diseases, little is known concerning the effect on an SP-induced event such as mast cell degranulation and the upregulation of adhesion molecules or the nitric oxide (NO) synthesis in endothelial cells. Our aim was to study the effect of bepotastine besilate on SP-induced degranulation of rat basophillic leukemia (RBL-2H3) cells and expression of adhesion molecules and NO synthesis in human dermal microvascular endothelial cel

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10

Gupta, Priya, Seema Baishnab, and Parveen Rewri. "Comparative evaluation of efficacy and safety of bepotastine besilate 1.5% ophthalmic solution versus olopatadine hydrochloride 0.1% ophthalmic solution in patients with vernal keratoconjunctivitis." International Journal of Basic & Clinical Pharmacology 10, no. 5 (2021): 552. http://dx.doi.org/10.18203/2319-2003.ijbcp20211652.

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Background: Vernal keratoconjunctivitis (VKC) is a chronic, seasonally exacerbated, allergic ocular inflammation. It affect children and young adults and has male predominance. The first line of treatment often used is dual acting drugs like olopatadine and bepotastine. It combine the immediate histamine receptor antagonism, coupled with mast cell stabilization with other anti-inflammatory properties. The present study was conducted to compare the efficacy and safety of olopatadine 0.1% and bepotastine 1.5% eye drops in VKC patients.Methods: This was a prospective, open label, randomized and c

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