Relevant bibliographies by topics / Bernard's college

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Bernard's college'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "Bernard's college"

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Reeve, M. D. "Acidalius on Manilius." Classical Quarterly 41, no. 1 (May 1991): 226–39. http://dx.doi.org/10.1017/s0009838800003694.

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Thomas Marshall, who became Rector of Lincoln College in 1672 and died in 1685, left to the Bodleian his collection of books and manuscripts. Two lists of the manuscripts appear in Edward Bernard's Catalogi librorum manuscriptorum Angliae et Hiberniae (Oxford, 1697), i (1). 272–3, 373–4, but both omit what is now called MS. Marshall 140, which F. Madan in the Summary Catalogue describes as follows
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Demaitre, Luke. "The Medical Notion of ‘Withering’ From Galen to the Fourteenth Century: The Treatise on Marasmus by Bernard of Gordon." Traditio 47 (1992): 259–307. http://dx.doi.org/10.1017/s036215290000725x.

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Some twenty years ago, when few major books of Galen were available in modern English, one of his lesser writings, the treatise Περὶ μαρασμοῦ was published in translation. Even while this translation was in press, Pearl Kibre unearthed in the Vatican Library a text De marasmode secundum sententiam Galieni, which was composed by Bernard of Gordon at Montpellier in the early 1300s and is the only systematic discussion of marasmus in the medical literature for some fifteen centuries after Galen. By further coincidence, these two texts made their appearance just as several historians of science and of medicine were drawing attention to the ancient and medieval interpretations of life as the interaction between ‘innate heat' and ‘radical moisture'—precisely the paradigms in which the concept of marasmus was rooted. In 1974, in a seminal article on the Humidum radicale in thirteenth-century medicine, Michael McVaugh offered a first assessment of Bernard's discussion. His positive appraisal suggested that the text was worth editing and analyzing on its own terms, an enterprise that became more feasible with the recognition of additional manuscripts, references, and implications. A critical and annotated edition is presented here, together with an effort to collate Bernard's treatment of marasmus with his other works, with the teachings of his colleagues, and with the Galenic tradition.
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Liptrot, Sarah, and Eleonore Breuning. "College visits Caribbean for conference and workshops." Bulletin of the Royal College of Surgeons of England 89, no. 9 (October 1, 2007): 310–11. http://dx.doi.org/10.1308/147363507x239370.

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The president of the Royal College of Surgeons of England, Bernard Ribeiro, was invited to participate in the fifth annual conference of the Caribbean College of Surgeons from 8–10 June 2007, following the success of previous visits. In recent years, the English College has run a successful Basic Surgical Skills (BSS) course in Barbados and Jamaica. We were delighted to continue this international educational collaboration by par ticipating in the 2007 BSS course, which this year included training in advanced laparoscopy.
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Armitage, James, Paul Cathcart, and Mayoni Gooneratne. "Presidential visit to Ghana." Bulletin of the Royal College of Surgeons of England 88, no. 6 (June 1, 2006): 202–3. http://dx.doi.org/10.1308/147363506x114063.

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The College president Mr Bernard Ribeiro was invited by the West African College of Surgeons (WACS) to participate in its annual conference in Ghana in February 2006. Along with the Association of Surgeons of Great Britain and Ireland (ASGBI), our College had also been asked by the conference committee to run an intercollegiate Basic Surgical Skills (BSS) course together with a Research Methods course. Mr Martyn Coomer, head of research at the College, assembled a team that included Professor Jerry Kirk (former Council member), Dr Jan van der Meulen (director of the College's clinical effectiveness unit) and three of the College's research fellows.
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Pedatella, R. Anthony. "DILM at Bernard Baruch College: An Open Letter." Hispania 68, no. 1 (March 1985): 199. http://dx.doi.org/10.2307/341644.

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Williams, Michael E. "Lisbon College—The Final Years." Recusant History 26, no. 4 (October 2003): 616–33. http://dx.doi.org/10.1017/s0034193200031794.

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A previous article gave an account of the difficulties besetting Lisbon College at the beginning of the twentieth century. These were due both to the unsettled state of Portugal where the new Republic was hostile to the Church and to the failure of Mgr James Warwick to win the support of his staff in revitalising the college after the long and rather monochrome presidency of William Hilton. Warwick’s failure led to an unfortunate difference of opinion among the staff of the college and in the absence of an Apostolic Nuncio in Lisbon, the traditional Protector of the College and the court of appeal, Cardinal Bourne sent Mgr Bernard Ward of Old Hall, Ware, to make an official visitation and report on the state of affairs in Lisbon.
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Gardner, Dugald. "William Rutherford Sanders (1828–1881), anatomist, physician, linguist and museum conservator." Journal of Medical Biography 28, no. 2 (October 18, 2018): 120–23. http://dx.doi.org/10.1177/0967772018801740.

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William Rutherford Sanders spent a childhood and early student days divided between Edinburgh and Montpelier, France before graduating in Medicine in Edinburgh. An early interest in the spleen was encouraged by a two-year period in Europe where he became familiar with the work of Helmholtz, Bernard and Henle. Returning to Edinburgh, his growing experience led to the position of assistant in the Infirmary pathology department. He conducted classes in the University of Edinburgh and on behalf of the Royal Colleges became familiar with the museum of the Royal College of Surgeons where he was chosen as Conservator in 1853. Criticised by 20th century historians for concentrating on verbal teaching rather than on the conservation of the museum, Sanders became a consultant physician to the Royal Infirmary in 1861 and in 1869 Professor of General Pathology. Throughout these years, Sanders gave as much time as possible to the study of the structure and function of the spleen and to neurological disorders such as hemiplegia. His later life was interrupted by a series of illnesses commencing with an abdominal abscess. A prolonged convalescence allowed the resumption of work but deranged vision and hemiplegia preceded his death on 18 February 1881.
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Brighton, Trevor, and Brian Sprakes. "Medieval and Georgian Stained Glass in Oxford and Yorkshire. The Work of Thomas of Oxford (1385–1427) and William Peckitt of York (1731–95) in New College Chapel, York Minster and St James, High Melton." Antiquaries Journal 70, no. 2 (September 1990): 380–415. http://dx.doi.org/10.1017/s0003581500070840.

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In the story of the survival and revival of glass-painting in post-Reformation England, York and Oxford play a significant part. York was especially important because it supported three important artists who helped to maintain the city as a major glass-painting centre, namely Bernard Dinninckhoff (fl. 1585-c. 1620), Henry Gyles (1645–1709), and William Peckitt (1731–95). Oxford's part lay in its patronage of glass-painters. Various colleges patronized foreign and native artists, in particular Abraham and Bernard van Linge, Henry Gyles, William Price and William Peckitt.
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Cruwys, Liz, and Beau Riffenburgh. "Bernard Stonehouse: biologist, writer, and educator." Polar Record 38, no. 205 (April 2002): 157–69. http://dx.doi.org/10.1017/s003224740001754x.

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AbstractThis is the first in a series of biographies entitled ‘Children of the Golden Age’, the purpose of which is to describe the background and contributions of a number of significant living figures in polar research, all of whom began their scientific careers and earned their Antarctic spurs in the years following World War II. Bernard Stonehouse was born in Hull on 1 May 1926. Joining the Royal Navy in 1944, he trained as a pilot, and in 1946–50 served as meteorologist, second pilot, dog-sledger, and ultimately biologist with the Falkland Islands Dependencies Survey, mainly from Base E, Stonington Island, Antarctic Peninsula. His first biological investigation was a winter study of breeding emperor penguins. Returning to Britain in 1950 he read zoology and geology at University College, London. Doctoral research at the Edward Grey Institute of Field Ornithology and Merton College, Oxford, involved an 18-month field study of king penguins on South Georgia. Between 1960 and 1968, as senior lecturer, later reader, in zoology, at University of Canterbury, Christchurch, New Zealand, he continued Antarctic and sub-Antarctic research in McMurdo Sound and on the New Zealand southern islands. A Commonwealth Research Fellowship at the University of British Columbia, 1970–71, gave him opportunities for research in the Yukon. After developing undergraduate and postgraduate studies in environmental science at the University of Bradford, 1972–83, he joined the Scott Polar Research Institute as editor of Polar Record, thereafter forming the Institute's Polar Ecology and Management Group, and heading a long-term study on the ecological impacts of polar tourism. At SPRI he continues to combine the two factors that have always played an important part in his life: working in polar regions and communicating with the general public on issues of biology, the environment, and conservation.
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Armitage, James, and Neil Russell. "The Future Delivery of Surgical Services: a meeting for managers and surgeons." Bulletin of the Royal College of Surgeons of England 89, no. 1 (January 1, 2007): 22–23. http://dx.doi.org/10.1308/147363507x163518.

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The structure of the NHS is currently undergoing radical reforms that will inevitably impact on the future delivery of surgical care in England. In light of these changes, The Royal College of Surgeons of England has set out to establish a greater understanding between surgeons and hospital managers. In October 2006, a meeting was held in the Lake District at Rheged, Europe's largest grass-covered building. It was attended by almost a hundred people and included both managers of NHS hospitals and those from the independent sector, chief executives, and consultant and trainee surgeons representing all of the surgical specialties. The meeting was hosted by the president of the College, Mr Bernard Ribeiro, and was facilitated by Professor Tony Mundy, medical director of University College Hospital and director of the Institute of Urology. The meeting took an interactive format and generated some lively debate.
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Dissertations / Theses on the topic "Bernard's college"

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Spradlin, Jamie Lynn. "Tolerance of Diversity, Collective Efficacy, and Criminal Victimization on a College Campus." Thesis, Virginia Tech, 2006. http://hdl.handle.net/10919/33686.

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Victimization and hate crimes are becoming more prominent on Americaâ s college campuses. Indeed, nearly 20,000 crimes of violence, and over 600 hate crimes, occurred on and around university campuses in 2003 (Department of Education 2004). Given its inverse relationship to crime at the aggregate level, (Sampson et al 1997), one possible means of reversing this trend would be to increase levels of collective efficacy across U.S. campuses. The purpose of this research is to determine if an individualâ s tolerance of diversity is related to their willingness to intervene in criminal or potentially criminal situations. That is, is tolerance of diversity related to collective efficacy at Virginia Tech? The research on collective efficacy is based on neighborhood level variables. This research, conducted in the â neighborhoodâ of Virginia Tech, focuses on collective efficacy and tolerance of diversity at the individual level. This research is unique in that it fills gaps in existing literature; to date, no research has analyzed the potential causes of collective efficacy at the individual level. Participants in this study will be asked to complete a survey regarding issues of diversity, tolerance and integration, and sense of belonging to community. The results will then be analyzed in order to gain some insight into this phenomenon. The main questions that will be explored in this research are: Does an individualâ s sense of belonging to his or her community and tolerance of diversity lead to their willingness to intervene if they see someone doing something wrong? That is, is sense of belonging to community and tolerance of diversity related to collective efficacy? Routine Activities Theory and studies of Collective Efficacy will be used to explore these questions.
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Jones, Jacqueline. "Post-Katrina Student Resilience: Perspectives of Nunez Community College Students." ScholarWorks@UNO, 2010. http://scholarworks.uno.edu/td/1137.

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This study examines the phenomenon of student resiliency as it relates to Nunez Community College students who returned to attend school in the community of St. Bernard Parish following Hurricane Katrina. Nunez Community College is located in Chalmette, Louisiana, fifteen miles east of the City of New Orleans. The community is adjacent to the Lower Ninth Ward. This study seeks to answer the questions of why the students returned to a disaster-stricken area to continue their studies and how the students coped in the aftermath. There is a significant gap in the literature on post-disaster resiliency and in particular, the role of education in post-disaster recovery. Twelve students who returned to Nunez Community College post-Katrina were interviewed using a Student Resilience Model as a conceptual framework. The perceptions of the students' post-disaster experiences resulted in five themes which included Individual Resilience, Post-Disaster Academic Integration, Post-Disaster Social Int
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Bala, Yamini. "Where Have All The Voices Gone? A Case Study in Marginalization Politics at the Robert J. Bernard Field Station of the Claremont Colleges." Scholarship @ Claremont, 2001. http://scholarship.claremont.edu/pomona_theses/68.

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This thesis is not intended to be an indictment of our leaders — well, not entirely, anyway. This thesis is meant to be an exercise in listening. I talked to a lot of people on every side of this issue, and tried hard to listen. I obviously have my biases, but I did my best to understand where everyone was coming from. I tried to evaluate groups instead of individuals as participants in this issue. My interviewees were requested to express views on behalf of the community group to which they belonged. I tried to find the opinions that best defined the majority of each group. Sometimes these came from resolutions, sometimes surveys, and other times analyses of local newspaper letters. In writing this up, I hoped to express the the voices I heard from a common ground. It seems that we've let our voices become antagonistic — that we've lost the will to embrace new opinions and engage in debate. I hope that people reading this might listen to the voices that are speaking — understand where they come from instead of preparing a rebuttal of their opinions. Consider our own actions and how they affect the situation. Think about whether we’re prepared to let this battle divide our community into the dreamers who get their way and those who don’t — or if we are ready to listen to one another, offer compromises, and do what really benefits this community the most. This thesis is an effort to explore different perspectives on a common issue and document the voices that have been cast aside and ignored. I originally wanted to speak for the Bernard Field Station, because I wasn’t sure how much longer it would be around to speak for itself. But I now realized it is futile. If you are willing to listen, the place speaks for itself ... and the story it tells is remarkable.
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Meyer, Frauke [Verfasser], and Bernard [Akademischer Betreuer] Moussian. "Regulation of Drosophila Motor Axon Pathfinding by the Metalloprotease Tolloid-related 1 (Tlr1) and the Collagen Drosophila multiplexin (Dmp) / Frauke Meyer ; Betreuer: Bernard Moussian." Tübingen : Universitätsbibliothek Tübingen, 2012. http://d-nb.info/1162699396/34.

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Dautrey, Philippe. "Des comptes aux œuvres : les travaux de l'église des Bernardins de Paris (1339-1342) et du Palais des Papes d'Avignon (1344-1345)." Paris, EHESS, 2006. http://www.theses.fr/2006EHES0088.

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Ce travail rapproche le chantier de l'église des Bernardins de Paris lancé par Benoît XII en 1338 de celui du Palais d'Avignon, engagé par Clément VI, en 1344, tels qu'ils apparaissent dans les registres de comptes des Archives Vaticanes IE181, IE197, IE228 et IE227. Il en reconstitue le fonctionnement. À Paris, un directeur des œuvres, Pons de Madières, est associé à un maître maçon, Bernard Podéros, qui sert de maître d'œuvre. À Avignon, l'œuvre Neuf d'abord rattaché à une administration des « Œuvres et édifices » relèvent ensuite d'un Jean de Louvres, maître des œuvres autonome. La gestion de ces chantiers est l'occasion d'une rationalisation des méthodes de travail (calendrier, emploi du temps, récupération de jours chômés, embauche régulière). Même soucis de rationalité dans les programmes des maîtres d'ouvrage et dans les appréciations de contemporains (Jean Dupin, Pétrarque, biographes), sensibles à « l'utilité » de ces œuvres
This work is, throught the account books of Vatican Archives IE181, IE197, IE228 and IE227, a comparison of two building sites : the church des Bernardins de Paris started by Benoît XII (1338) and the Palais d'Avignon worked out by Clement VI (1344) and more precisely of the site management and its organisation. In Paris, Pons de Madières, "directeur des œuvres" was working in collaboration with Bernard Podéros, mason master who was acting as "maître d'œuvre". In Avignon, "l'œuvre Neuf" was first dependant on the administration of "Œuvres et édifices", then on Jean de Louvres autonomous "maître des œuvres". The management of this two building sites was the opportunity for rationalizing working methods using for example : calendar, time table, recovery of holidays, regular work. The rationalization spirit was also found in the contractors' programs and recognized by contemporaneous writers (Jean Dupin, Pétrarque, biographers) who appared to be very attracted by the useful purpose of these tools
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Pronto, Lindon N. "Exploring German and American Modes of Pedagogical and Institutional Sustainability: Forging a Way into the Future." Scholarship @ Claremont, 2012. http://scholarship.claremont.edu/pitzer_theses/21.

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Rooted deep in Germany's past is its modern socio-political grounding for environmental respect and sustainability. This translates into individual and collective action and extends equally to the economic and policy realm as it does to educational institutions. This thesis evaluates research conducted in Germany with a view to what best approaches are transferable to the United States liberal arts setting. Furthermore, exemplary American models of institutional sustainability and environmental education are explored and combined with those from abroad to produce a blueprint and action plan fitting for the American college and university.
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Nevils, Henry Lane. "The actions of institutional leadership at two Louisiana community colleges in the aftermath of Hurricanes Katrina and Rita." 2013. http://hdl.handle.net/2152/23198.

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In August and September of 2005, Hurricanes Katrina and Rita devastated the Gulf Coast with damages estimated at $85 billion. Hurricane Katrina was so devastating that the number of lives lost and injuries sustained is still being calculated. Hurricane Rita, which made landfall in the southwestern part of the Louisiana just a few weeks after Katrina, did not cause as much damage as Katrina but was devastating nonetheless. In both cases, two Louisiana community colleges, Nunez Community College and SOWELA Technical Community College, were damaged to the point that many doubted that either college would have a future. Both community colleges, however, continued classes and are in operation today. This study examines the actions of the institutional leadership at Nunez Community College and SOWELA Technical Community College in the aftermath of Hurricanes Katrina and Rita. A constructivist grounded theory approach was used to conduct case studies on each college. A substantive theory emerged from the findings explaining the resiliency of both institutions.
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Pierik, Derk, Ginkel Aileen Van, and Haan Phil de. "Perspective vol. 19 no. 3 (Jun 1985)." 2013. http://hdl.handle.net/10756/251272.

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Pierik, Derk, Ginkel Aileen Van, and Haan Phil de. "Perspective vol. 19 no. 3 (Jun 1985)." 1985. http://hdl.handle.net/10756/277602.

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Books on the topic "Bernard's college"

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Liekis, Algimantas. Prof. Bernardas Kodatis: Sugrįžusio lietuvio gyvenimas : apie prof. Bernardą Kodatį, astronomą ir geodezinės astronomijos Lietuvoje pradininką : monografija. Vilnius: Mokslotyros institutas, 2010.

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Le Collège des Bernardins: Histoire d'une reconversion. Paris: Éditions Alternatives, 2009.

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Drake, Frances Bernard. Two men and an idea: Robert Bernard with James Blaisdell, partners in pioneering the Group Plan of the Claremont Colleges. Claremont, Calif: Claremont University Center, 1996.

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Georgi, Galabov, Zhang Sophie, and Dante Alighieri 1265-1321, eds. Vers le Paradis: Dante au Collège des Bernardins. Paris: Collège des Bernardins, 2010.

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York, New York (State) Office of the State Deputy Comptroller for the City of New. City University of New York Baruch College, review of executive programs. [New York, N.Y: Office of the State Deputy Comptroller, 1993.

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Magubane, Bernard. Bernard Magubane: My life & times. Scottsville, South Africa: University of KwaZulu-Natal Press, 2010.

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Hosmer, Charles Bridgham. Bernard Maybeck and Principia College: The historic district : guidebook. Elsah, Ill: Principia College, 1998.

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Bernard Maybeck at Principia College: The art and craft of building. Layton, Utah: Gibbs Smith, 2004.

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Berrol, Selma Cantor. Getting down to business: Baruch College in the city of New York, 1847-1987. New York: Greenwood Press, 1989.

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Le cas Bernard Faÿ: Du Collège de France à l'indignité nationale. [Paris]: Gallimard, 2009.

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Book chapters on the topic "Bernard's college"

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Davis, Michael T. "Cistercians in the City: The Church of the Collège Saint-Bernard in Paris." In Perspectives for an Architecture of Solitude, 223–34. Turnhout: Brepols Publishers, 2004. http://dx.doi.org/10.1484/m.mcs-eb.3.1856.

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Feffer, Andrew. "The Stooge Grebanier." In Bad Faith, 36–53. Fordham University Press, 2019. http://dx.doi.org/10.5422/fordham/9780823281169.003.0003.

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This chapter turns to the inquiry’s first main “friendly” or cooperative witness, Brooklyn College (BC) English professor, Bernard Grebanier. Windels began by investigating BC because of its reputation for left-wing activism and the involvement of teachers and students in Popular Front causes. Grebanier, like many of his colleagues, joined the Communist Party because of its strong stance against European fascism, anti-Semitism, and right-wing movements in the United States. Although Grebanier was an unreliable witness, Windels led him to promote the myth that Brooklyn faculty indoctrinated their students.
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Schindler, Thomas E. "The Pathway to Bacterial Genetics." In A Hidden Legacy, 15–30. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780197531679.003.0003.

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This chapter reviews Esther Zimmer’s early training, as she set out on a parallel career pathway, from Neurospora to bacteria, to her future husband Joshua Lederberg. While still a junior at Hunter College, Zimmer found the best possible mentor in Bernard Ogilvie Dodge, the foremost expert in Neurospora, the new model organism of genetic research. After graduation, Dodge helped her gain further research experience at the Industrial Hygiene Research Laboratory in Bethesda, Maryland, where she worked with Alexander Hollaender, an expert in radiation biology. After two years of training in the procedures for developing X-ray and UV induced mutations, Zimmer acquired her bona fides for graduate school. She was accepted to graduate school at Stanford University because of Dodge’s association with George Beadle, who, with Edward Tatum, had developed a new paradigm for biochemical genetics: “one gene: one enzyme.” In 1946, their similar experiences in Neurospora research brought Joshua and Esther together.
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Glasscock, Robin. "Maurice Warwick Beresford 1920–2005." In Proceedings of the British Academy, Volume 161, Biographical Memoirs of Fellows, VIII. British Academy, 2009. http://dx.doi.org/10.5871/bacad/9780197264577.003.0002.

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Maurice Warwick Beresford (1920–2005), a Fellow of the British Academy, was an economic and social historian born in Sutton Coldfield, Warwickshire to Harry Bertram Beresford and Nora Elizabeth Jefferies. He was ill at ease in the social fabric of Jesus College in the late 1930s. Still, Beresford flourished academically under the guidance of an understanding Tutor, Bernard Manning, and a supportive Director of Studies, Charles Wilson. Social work of various kinds was to remain a major interest throughout his life. In the autumn of 1942, Beresford moved to Rugby to take up a residential post as Sub-Warden (and later Warden, 1943–1948) of the Percival Guildhouse, an adult education centre. By early 1946, he had applied for posts in history at Glasgow and economic history at Nottingham. While settling in at the University of Leeds in 1948, several papers resulting from his archival and fieldwork in the midlands were published. But before moving to Leeds, Beresford trespassed into archaeology for the first time. Beresford retired from Leeds in 1985.
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Pierrot, Anne Herschberg. "Barthes, the Desire to Write, and the Prevision of the Work." In Interdisciplinary Barthes, 276–87. British Academy, 2020. http://dx.doi.org/10.5871/bacad/9780197266670.003.0017.

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This chapter explores the connections between Le Lexique de l’auteur (the seminar of 1973–4 in which Barthes reflects on the genesis of the text that will become Roland Barthes par Roland Barthes), La Préparation du roman (his last Collège de France lecture course of 1978–80), and critical essays he wrote in the mid- and late 1970s on scription, the ductus, and writing as gesture (from an anthropological point of view, as in the posthumously published Variations sur l’écriture, and within the paintings of Bernard Réquichot and Cy Twombly). The main focus will be on Barthes’s reflection, across the two seminars, on the idea of the virtual work: his exploration of the modalities of literary genesis in the grammatical mood of the ‘as if’, and his development of ways of modelling literary genesis through the concept of the œuvre-maquette. This bringing together of modelling, genesis, and writing as process, placed in relation to the desire to write as a significant dimension of actual writing, is one of the strikingly original aspects of Barthes’s 1970s thought. It is one that the posthumous publication of the seminars and lectures allows us to understand.
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Taber, Douglass F. "Enantioselective Construction of Arrays of Stereogenic Centers: The Breit Synthesis of (+)-Bourgeanic Acid." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0044.

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Kyungsoo Oh of Indiana University Purdue University Indianapolis devised (Organic Lett. 2009, 11, 5682) a new ligand that with Cu delivered predominantly one diastereomer of the Henry adduct 3, and with Zn delivered the other. Liu-Zhu Gong of the University of Science and Technology of China reported (Angew. Chem. Int. Ed. 2009, 48, 6503) the Darzens condensation of the diazoacetamide 5 with a variety of aldehydes to give the corresponding epoxy amides with high diastereo- and enantiocontrol. Michael J. Krische of the University of Texas, Austin, applied (Organic Lett. 2009, 11, 3108, 3112) his asymmetric allylation to a variety of primary diols including 7, leading to the homologated product 9. M. Christina White of the University of Illinois showed (J. Am. Chem Soc. 2009, 131, 11707) that Pd-mediated oxidative amination of carbamate 10 delivered the protected 1,3-amino alcohol 11 with high diastereocontrol. James P. Morken of Boston College devised (J. Am. Chem Soc. 2009, 131, 9134) a Pt catalyst for the asymmetric bis-boration of dienes. The allyl borane prepared from 12 added with high stereocontrol to benzaldehyde, to give, after oxidation, the diol 13. Carlos F. Barba III of Scripps/La Jolla optimized (Angew. Chem. Int. Ed. 2009, 48, 9848) an organocatalyst for the enantioselective conjugate addition of an alkoxy aldehyde 15 to a nitroalkene. Do Hyun Ryu of Sungkyunkwan University found (Chem. Commun. 2009, 5460) that an organocatalyst could also mediate the dipolar cycloaddition of a diazo ester 18 to an unsaturated aldehyde, giving 19 with high diastereo- and enantiocontrol. Francesco Fini and Luca Bernardi of the University of Bologna developed (J. Am. Chem Soc. 2009, 131, 9614) an organocatalyst that effected enantioselective dipolar cycloaddition of the nitrone derived from 20 to the unsaturated ester 21. Kevin Burgess of Texas A&M optimized (J. Am. Chem Soc. 2009, 131, 13236) an Ir catalyst for the enantioselective hydrogenation of trisubstituted alkenes such as 23. In the course of a synthesis of (+)-faranal, Varinder K. Aggarwal of the University of Bristol described (Angew. Chem. Int. Ed. 2009, 48, 6317) a one-pot procedure for the conversion of the allyl borane 25 into 27.
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Conference papers on the topic "Bernard's college"

1

Nichols, W. L., S. E. Kaese, D. A. Gastineau, L. A. Otteman, and E. J. W. Bowie. "BERNARD-SOULIER SYNDROME: WHOLE BLOOD DIAGNOSTIC ASSAYS OF PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644561.

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Diagnosis of Bernard-Soulier syndrome (BSS) is complicated by the difficulty of separating the giant platelets from other blood cells to pursue analyses of platelet function and structure. We report on the utility of three whole blood assay techniques for diagnosis of a patient with BSS. To our knowledge, these three techniques have not been simultaneously applied or compared for efficacy in laboratory diagnosis of BSS. (1) Whole blood platelet aggregation responses, studied with an electrical impedence aggregometer, were equivalent to those more laboriously obtained using platelet-rich plasma prepared by unit gravity sedimentation, studied with an optical light transmittance aggregometer. Platelet aggregation responses were normal with ADP or collagen stimulation, and absent with Ristocetin or bovine plasma stimulation. (2) Whole blood radioimmunoassay of platelet glycoprotein (GP) expression was performed using iodinated murine monoclonal antibodies HP1-1D (anti-GP IIb/IIIa) and 6D1 (anti-GPlb, kindly supplied by Dr. Barry Coller, Stony Brook, NY). After incubation with citrated whole blood, centrifugation was used to separate cell-bound antibody which was quantitated with a gamma counter. The patient’s whole blood had a normal level of cell-bound GP Ilb/IIIa, but a markedly reduced level of cell-bound GP lb (5% of normal mean; n = 20). (3) Whole blood smear immunocytochemical staining with the monoclonals (indirect immuno-alkaline phosphatase technique), and qualitative analysis by light microscopy, revealed a marked reduction of GP lb expression by the patient’s giant platelets, whereas GP Ilb/IIIa expression was normal. This latter technique might be especially valuable as a screening technique when the patient is not directly available for laboratory study. Together with the patient’s life-long history of thrombocytopenia and moderate bleeding diathesis, and other laboratory observations including markedly prolonged bleeding times and reduced whole blood prothrombin consumption, these data established diagnosis of BSS. We conclude that these three relatively simple assays of platelets in whole blood should be of particular value in the laboratory differential diagnosis of patients with congenital thrombocytopenias and giant platelet syndromes.
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2

Wyler, B., and K. J. Clemetson. "THE ROLE OF GPIb IN PLATELET ACTIVATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642922.

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Platelet membrane glycoprotein lb (GPIb) is known to contain a receptor for von Willebrand factor (vWf) and for thrombin. The role of GPIb in platelet activation was investigated by comparing the effect of removal of the binding sites by specific proteolysis with that of blocking them using specific antibodies. Specific removal of the 45 kDa outer part of GPIb by treatment of platelets with human leukocyte elastase caused loss of platelet agglutination response to von Willebrand factor (vWf) but also a weaker activation by thrombin similar to that found with Bernard-Soulier syndrome platelets which lack GPIb. Removal of the major part of the external region of the GPIba chain, including the 45 kDa domain, by calcium activated protease or by chymotrypsin, produced similar effects. The 45 kDa region of GPIba was purified by tryptic cleavage of isolated glycocalicin followed by gel filtration. Antibodies to this fragment were produced in rabbits and showed high specificity and affinity for the 45 kDa polypeptide. Fab fragments of IgG prepared from this anti serum affect platelet response to vWf and thrombin in a dose-dependent way. In both protease-treated and antibody-treated platelets the reduced response to thrombin, but not to vWf could be overcome by increasing the dose of thrombin. In contrast to removal of the 45 kDa domain, antibody treatment affected not only the platelet response to vWf and thrombin but also to collagen, ADP, PAF and arachidonic acid. Only the response to the calcium ionophore A23,187 was unaltered.Though not the essential receptor GPIb is clearly involved in platelet response to thrombin. A possible mechanism could involve a conformational change in the cytoplasmic/inter-membranous part of GPIb induced by binding of thrombin to the 45 kDa domain. Binding of antibodies might affect platelet activation by other agonists via a general down regulation effect. These results support the two receptor models for thrombin activation of platelets as proposed for other cell -types. In platelets the first receptor appears to be GPIb but the second receptor has not yet been identified.
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