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Journal articles on the topic 'Betel nut extract'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Phaechamud, T., and Sasiprapa Chitrattha. "Development of Soaps Containing Betel Nut Extract." Advanced Materials Research 506 (April 2012): 339–42. http://dx.doi.org/10.4028/www.scientific.net/amr.506.339.

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Areca catechu L. or betel nut tree is one of popular traditional herbal medicines used in Thailand. The betel nut, seed of Areca catachu contains polyphenols, flavonoids and alkaloids that have a potent muscarinic action, which the potential application in Alzheimers disease and antioxidative effect have been mentioned. The anti-aging effects of Areca catechu L. extract on skin has been investigated previously which it could improve the skin hydration, skin elasticity, and wrinkle reduction. The methanolic extract of Areca catechu L. seed gave high antioxidant activity than the other parts of

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2

Ida Bagus Oka Suyasa, Trisna Bagus Wibawa, Ni Made Defy Janurianti, and Putu Diah Wahyuni. "Antibacterial Activity of Legundi Leaf Extract (Vitex trifolia L.) with Betel Leaf Extract (Piper betle L.) against Staphylococcus aureus." SEAS (Sustainable Environment Agricultural Science) 6, no. 2 (2022): 112–18. http://dx.doi.org/10.22225/seas.6.2.5843.111-117.

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One of the plants that have antibacterial compounds is legundi leaves and betel leaves. The combination of the two extracts is expected to provide a synergistic effect so that it can increase the inhibition of Staphylococcus aureus bacteria. This study used the disc diffusion test method to determine the antibacterial activity. The data obtained were analyzed using the Kolmogrov-Smirnov test and continued with the one-way Anova test. The average diameter of the inhibition zone in this study ranged from 6.43 mm to 18.63 mm where legundi extract had a medium category, betel extract had a moderat

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3

Dasugo, Angeline Dario. "Anthelmintic Effects of Betel Nut to Free-Range Chicken." European Journal of Theoretical and Applied Sciences 2, no. 3 (2024): 18–23. http://dx.doi.org/10.59324/ejtas.2024.2(3).02.

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The study aims to evaluate the efficacy of Processed Betel Nut as an anthelmintic to Free-Range Chickens. The research employed a Completely Randomized Design (CRD) and utilized 90 heads of uniformed experimental free–range chickens. The experimental birds were divided into 5 treatment combinations replicated thrice as follows: C- (pure water), C+ (commercial anthelmintic), S1L1 (Betel nut extract (10ml), S1L2 (Betel nut extract (20ml), S1L3 – Betel nut extract (30ml). The anthelmintic effect was observed during days 1,2,3,7,14,21, and 28 of the study. Prior to the allotment of the birds, feca

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Angeline, Dario Dasugo. "Anthelmintic Effects of Betel Nut to Free-Range Chicken." European Journal of Theoretical and Applied Sciences 2, no. 3 (2024): 18–23. https://doi.org/10.59324/ejtas.2024.2(3).02.

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The study aims to evaluate the efficacy of Processed Betel Nut as an anthelmintic to Free-Range Chickens. The research employed a Completely Randomized Design (CRD) and utilized 90 heads of uniformed experimental free–range chickens. The experimental birds were divided into 5 treatment combinations replicated thrice as follows: C- (pure water), C+ (commercial anthelmintic), S1L1 (Betel nut extract (10ml), S1L2 (Betel nut extract (20ml), S1L3 – Betel nut extract (30ml). The anthelmintic effect was observed during days 1,2,3,7,14,21, and 28 of the study. Prior to the allotment of the

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Afni, Nur, Nasrah Said, and Yuliet Yuliet. "UJI AKTIVITAS ANTIBAKTERI PASTA GIGI EKSTRAK BIJI PINANG (Areca catechu L.) TERHADAP Streptococcus mutans DAN Staphylococcus aureus." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 1, no. 1 (2015): 48–58. http://dx.doi.org/10.22487/j24428744.2015.v1.i1.7900.

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Betel nut (Areca catechu L.) is a natural material that has antibacterial activity content against Streptococcus mutans and Staphylococcus aureus. Under these conditions, betel nuts were formulated in a toothpaste that has antibacterial activity.This study aims to determine the antibacterial activity of betel nut extract in toothpaste with various concentrations of 1.5%, 3% and 4.5% and to determine the effective concentration of betel nut extract in toothpaste that meets the physical quality of chemical and antibacterial activity against Streptococcus mutans and Staphylococcus aureus. The res

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6

Thepwatee, Sukanya, Panida Adam, Pimsiri Boonpongha, et al. "Color Masking of Betel Nut Extract Using Encapsulation Technology for Nutricosmeceutical Applications." Key Engineering Materials 824 (October 2019): 245–53. http://dx.doi.org/10.4028/www.scientific.net/kem.824.245.

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In this work, encapsulation technology—nanoemulsions (NEs) and nanostructured lipid carriers (NLCs)—was applied for color masking of betel nut extract for oral and skin applications. Types and extents of surfactant and lipid as well as homogenization process showed essential roles on physical properties of the encapsulated betel nut extract. Comparing to solution of betel nut extract in methanol, the degree of lightness of the optimized NE and NLC formulations improved more than 44 time compared to unencapsulated formulation. The optimized NE and NLC were most stable at 25 °C. Extreme storage

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7

Khatun, Masuda, and Md Mahfuzul Hoque. "Antibacterial activity of ethanol extracts of betel leaf (Piper betle L.) and areca (Areca catechu L.) nuts against food borne and oral pathogens." Bangladesh Journal of Microbiology 38, no. 1 (2021): 15–19. http://dx.doi.org/10.3329/bjm.v38i1.55531.

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Antimicrobial activity of ethanol extracts of betel leaf (Piper betle L.) and areca nut (Areca catechu) against six food borne enteric pathogens viz. Staphylococcus aureus (ATCC 25923), Staphylococcus epidermidis (icddr,b), Salmonella typhimurium (AIM-40, icddr,b), Escherichia coli (ATCC 25922), Escherichia coli O157:H7 (ATCC 12079) and Bacillus cereus (ATCC 12079), and four oral pathogens such as isolates 1 & 2 of each of the two bacteria viz. Staphylococcus sp. and Pseudomonas sp. was investigated. Ethanol extract of betel leaf produced highest zone of inhibition (18.0 ± 1.91 mm) against

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SARI, MULIA SAFRIDA, and AHMAD RIDWAN. "Efektivitas Ekstrak Etanol Biji Pinang Terhadap Densitas GLUT4 pada Sel-Sel Otot Rangka Mencit yang Terinduksi Hiperglikemia." Jurnal Sumberdaya Hayati 2, no. 2 (2017): 52–58. http://dx.doi.org/10.29244/jsdh.2.2.52-58.

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Betel nut (Areca catechu) was proven to have antihyperglycemic activity through increased PI3K pathway in the GLUT4 translocation in cells. However, research on the ethanol extract of betel nut in Indonesia is still limited. The main problem in this study was whether the ethanol extract of betel nut could improve glucose tolerance in a two-hour postprandial period and whether the ethanol extract of betel nut could induce GLUT4 translocation in skeletal muscle cells of mice induced hyperglycemia. Glucose tolerance test results showed that treatment of the ethanol extract of betel nut for 24 day

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9

Gunawan, Elsye, Mega Silvia, and Nur Fadilah Bakri. "Gel of Betel (Areca Catechu Linn.) Nut Ethanol Extract Activity Test as Cuts Healing against Diabetic Rabbits (Oryctolagus cuniculus)." Journal of Clinical Trials and Regulations 5, no. 1 (2023): 41–52. http://dx.doi.org/10.46610/jctr.2023.v05i01.004.

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Background: Areca nut (Areca catechu Linn.) contains the main components in the form of tannins, flavonoids, alkaloids, and saponins. People usually use the young betel nut as cuts medicine by mashing it and applying it directly to the cuts cut area or by boiling the betel nut and the boiled water is used to clean cuts and other skin infections. Objective: The purpose of this study was to determine the effect of giving betel nut (Areca catechu Linn.) ethanol extract gel and to determine the most effective concentration of cuts healing in diabetic rabbits (Oryctolagus cuniculus). Method: This s

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10

Prasko, Prasko, Yaya Widyatmoko, and Sadimin Sadimin. "The Effect of Gargling Areca Nut Extract (Areca catechu L) 2,5% Against Plaque pH and Saliva pH." Jurnal Kesehatan Gigi 9, no. 2 (2022): 148–53. http://dx.doi.org/10.31983/jkg.v9i2.8504.

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ABSTRACTThe most common dental and oral health problems are dental caries and periodontal disease caused by dental plaque. Dental plaque is a soft deposit consisting of microorganisms found on a matrix that is formed and adheres tightly to the tooth surface. Bacteria in plaque will metabolize food waste, especially the type that can be fermented so that it will produce acid. The acid produced will lower the plaque pH to 4.5-5.0 wthin 1-3 minutes and return to normal at pH 7 within 30-60 minutes. Plaque buildup on the tooth surfaces is related to plaque pH salivary pH. The continuous decrease i

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Sumardi, Surmadi, Nilsya Febrika Zebua, Vriezka Mierza, Reihan Maurani Arafah, Qhairunnisa Qhairunnisa, and Riska Amalia. "Profil Noda Ekstrak Kloroform : Metanol (2:1) dan Aktivitas Bslt Kulit Batang Nyirih (Xylocarpus Granatum)." Journal of Pharmaceutical and Health Research 4, no. 2 (2023): 326–32. http://dx.doi.org/10.47065/jharma.v4i2.3678.

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Nyirih plants (Xylocarpus granatum) grows along the edge of the sea, and in other salty environments. Chemical compounds contained in the bark of the betel nut (Xylocarpus granatum) include alkaloids, triterpenoids, steroids, saponins, and flavonoids. The content of lipid compounds in the bark of betel nut (Xylocarpus granatum) has not been widely studied, including toxicity to cells. This study aims to determine the profile of stains on the bark extract of nyirih (Xylocarpus granatum) and to determine the toxicity of the bark extract of nyirih (Xylocarpus granatum). This research method is ex

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12

Sitompul, Erly, Ahmad Hafizullah, Yosy Cinthya Eriwaty Silalahi, and Realisni Telaumbanua. "UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP PERTUMBUHAN BAKTERI Escherichia coli, Shigella dysentriae, DAN Salmonella typhi." JURNAL FARMANESIA 4, no. 2 (2017): 79–83. http://dx.doi.org/10.51544/jf.v4i2.2705.

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One of the medicinal plants is the areca nut (Areca catechu L.) from the Arecae family which has the potential as an anticancer having antioxidant and antimutagenic, astringent, and anthelmintic effects. Areca nut seeds contain alkaloids, such as arekoline, arekolidine, arekain, guvakolin, guvasine and isoguvasine. This study aims to determine the characteristics of the betel nut (Areca catechu L.) simplicia, class of compounds, and the antibacterial activity of the ethanol extract of areca nut (Areca catechu L.) against the growth of Escherichia coli, Shigella dysentriae, and Salmonella typhi

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Lestari, Uce, Ardi Novra, and Romi Kurniadi. "Chewable Tablet Formulation from Ethanol Extracts of Betel, Areca, and Gambir as a Substitute for Betel." Jurnal Jamu Indonesia 10, no. 1 (2025): 49–54. https://doi.org/10.29244/jji.v10i1.311.

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The tradition of betel nut needs to be preserved because it is useful for maintaining oral health and the digestive system, but this betel nut has an impact on oral cavity injuries. Therefore, to prevent injuries to the oral cavity, this research makes an interesting innovation from the betel nut tradition in the form of formulating safe chewable tablets using natural ingredients, such as betel nut, areca nut, and gambier. This study aimed to determine the best chewable tablet formula from three formulas with different concentrations of betel, areca nut, gambier, and whiting, by testing the ph

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14

Efdi, Mai, M. Iqbal Alfarisyi, and Bustanul Arifin. "Isolasi Senyawa Metabolit Sekunder Dari Fraksi Aktif Antibakteri Pada Tumbuhan Sirih Merah (Piper porphyrophyllum)." Jurnal Kimia Unand 12, no. 2 (2022): 1–7. http://dx.doi.org/10.25077/jku.12.2.1-7.2023.

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The red betel plant (Piper porphyrophyllum) belongs to the Piperaceae family which is traditionally used to treat various diseases, including headaches, bone pain, chest tightness, leprosy, stomach ache, as well as for various other diseases such as skin diseases and diabetes. In this study, the antibacterial activity was tested for the hexane, ethyl acetate and methanol extracts of red betel nut using the disc diffusion method and the isolation of secondary metabolites from the hexane fraction of red betel nut using column chromatography technique. Determination of the antibacterial activity

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15

Wuisan, Jane, Bernat Hutagalung, and Wellsy Lino. "PENGARUH PEMBERIAN EKSTRAK BIJI PINANG (ARECA CATECHU L.) TERHADAP WAKTU PERDARAHAN PASCA EKSTRAKSI GIGI PADA TIKUS JANTAN WISTAR (RATTUS NORVEGICUS L.)." JURNAL ILMIAH SAINS 17, no. 1 (2015): 129. http://dx.doi.org/10.35799/jis.15.2.2015.9572.

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PENGARUH PEMBERIAN EKSTRAK BIJI PINANG (ARECA CATECHU L.) TERHADAP WAKTU PERDARAHAN PASCA EKSTRAKSI GIGI PADA TIKUS JANTAN WISTAR (RATTUS NORVEGICUS L.) ABSTRAK Biji pinang (Areca catechu L.) merupakan salah satu tanaman obat yang dikenal masyarakat dapat menghentikan perdarahan. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak biji pinang terhadap waktu perdarahan pasca ekstraksi gigi pada tikus jantan galur Wistar. Pada penelitian ini metode yang digunakan merupakan eksperimental. Ekstrak biji pinang didapatkan dengan cara maserasi dan penguapan menggunakan Rotary vacuum

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Munira, Munira, Galuh Trioktafiani, and Muhammad Nasir. "UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK DAUN SIRIH DAN BIJI PINANG SERTA GAMBIR TERHADAP Streptococcus mutans." Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan 5, no. 2 (2020): 298–308. http://dx.doi.org/10.36387/jiis.v5i2.501.

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Chewing the betel leaf is a proses of concocting a mixture of several ingredients such us betel leaves, areca nuts and gambier were known to provide a refreshing teste, overcoming stress and believed can strengthen teeth and gums. In addition, these plants also suspected of having antibacterial potential. This research was conducted to determine the ability of combination of betel leaf extract, areca nut and gambier against Streptococcus mutans. This research was experimental by using Completely Randomized Design (CRD) with 8 treatments which is P0 (aquadest), P1{combination of betel leaf extr

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Mat Salleh, Noor Fadilatul Akmal, Ahmad Azlina, Masitah Hayati Harun, et al. "Cytotoxicity and Morphological Effects of Aqueous Areca Nut Crude Extract on L929 Fibroblast Cell Line." Asian Journal of Medicine and Biomedicine 4, no. 1 (2020): 34–41. http://dx.doi.org/10.37231/ajmb.2020.4.1.328.

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Betel quid chewing is a detrimental recreational habit amongst Asians and a risk factor for oral cancer. Arecoline, a component of areca nut (a major constituent of betel quid) is a known carcinogen. However, the effect of areca nut crude extract is not much studied. To evaluate the cytotoxicity and morphologic effects of areca nut aqueous extract on mouse fibroblast cell line (L929). Dried raw areca nut obtained from a local market in Kota Bharu, Kelantan was prepared and suspended in DMEM (Dulbecco’s Modified Eagle’s medium), prior to serial dilution of 1.56, 0.781, 0.39, 0.195, 0.0976, 0.04

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Suparno, Nilasary Rochmanita, Citra Monika Sainti Camalin, and Chintami Setyawan Putri. "Pengaruh Formulasi Pasta Gigi Kombinasi Ekstrak Etanol Daun Sirih (Piper betle L), Biji Pinang (Areca catechu) dan Gambir (Uncaria gambir) terhadap Hambatan Pertumbuhan Bakteri Streptococcus Mutans." CERATA Jurnal Ilmu Farmasi 11, no. 2 (2020): 15–21. http://dx.doi.org/10.61902/cerata.v11i2.139.

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Appropriate use of toothpaste is an effort to reduce problems in the oral cavity, namely reducing plaque that causes dental caries. One of the advantages of herbal toothpaste compared to some toothpastes on the market is that it does not use Sodium Lauryl Sulphate (SLS) which often causes side effects on the oral mucosa. Betel leaf, areca nut and gambier are herbal ingredients which are proven to be effective in inhibiting bacterial growth. To determine the combination of betel leaf, areca nut, and gambier extract ethanol toothpaste in inhibiting the growth of Streptococcus mutans bacteria. Th

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Ningsih, Wida. "FORMULASI DAN UJI EFEKTIVITAS ANTIBAKTERI EDIBLE FILM EKSTRAK BIJI PINANG (Areca catechu Linn)." JIFFK : Jurnal Ilmu Farmasi dan Farmasi Klinik 15, no. 2 (2018): 71. http://dx.doi.org/10.31942/jiffk.v15i2.2569.

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ABSTRACTThe tannins contained in areca nut extract can inhibit the growth of Streptococcus mutans bacteria. To facilitate the use of betel seed extract as an antibacterial, it was formulated into an edible film with a concentration of 2.5%, 3% and 3.5%. Making edible films using solvent casting method and testing antibacterial activity using blood agar diffusion method. The edible film of areca nut extract made an evaluation included organoleptic, thickness, brittleness, water content, pH, and swelling test. The evaluation results of betel nut edible fim extract showed almost the same characte

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Liu, Jin, Li Ma, Senwen Deng та ін. "Deep Eutectic Solvents for Efficient and Selective Extraction of α-Glucosidase Inhibitors from Waste Seeds of Refined Betel Nuts". Foods 13, № 7 (2024): 1070. http://dx.doi.org/10.3390/foods13071070.

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During the production process of refined betel nuts in China, a large amount of processing by-product, betel nut waste seeds, is generated. Betel nut waste seeds are rich in bioactive elements, but they have not been effectively utilized yet. In this study, an ultrasonic-assisted deep eutectic solvent method (DES) was used to selectively extract α-glucosidase inhibitors from waste seeds. Compared with traditional extraction solvents such as water and ethanol, the extraction efficiency of specific DESs is higher, and the content of alkaloids in the extracts is lower. However, it should be noted

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Tiandho, Yuant, Purwati Purwati, Marlina Marlina, Mahjur Mahjur, and Widodo Budi Kurniawan. "Dye Sensitized Solar Cell (Dssc) With Areca Extract As A Natural Dye Sensitized." KONSTAN - JURNAL FISIKA DAN PENDIDIKAN FISIKA 7, no. 1 (2022): 18–24. http://dx.doi.org/10.20414/konstan.v7i01.102.

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Dye-sensitized Solar Cell (DSSC) is a solar cell that uses dye as one of its components. DSSC is interesting to develop because it can be fabricated simply with low production costs. This study aims to develop a DSSC that uses dye-sensitized from natural ingredients to be environmentally friendly. We chose betel nut (Areca catechu L.) as a natural dye source because betel nut has a reddish-brown color and is often used as a natural dye. The stages of this research consisted of betel nut extraction, TiO2 deposition, manufacture of a carbon layer on the counter electrode, and DSSC fabrication. M

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Asrianto, Asrianto, Asrori Asrori, Indra Taufik Sahli, Risda Hartati, Fajar Bakti Kurniawan, and Rina Purwati. "Bioaktivitas Ekstrak Etanol Biji Pinang (Arecha catechu L.) terhadap Staphylococcus aureus dan Escherichia coli." Jurnal Sains dan Kesehatan 3, no. 6 (2021): 839–45. http://dx.doi.org/10.25026/jsk.v3i6.702.

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Areca nut (Areca catechu Linn) is a plant that is widely distributed in tropical and subtropical regions. People have used it to treat various health problems. This study aims to determine the ability of betel nut ethanol extract to inhibit the growth of Staphylococcus aureus and Escherichia coli bacteria. The research method is experimental. Stages of research, first the betel nut is dried by aerating for 7-10 days. After drying, the seeds are ground into powder. The extraction stage of the active compounds uses the maceration method using 92% ethanol, evaporation is carried out using a rotar

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Anto, Endy Juli, Aznan Lelo, Syafruddin Ilyas, and Marline Nainggolan. "Effect of Ethanol Extract and Ethyl Acetate Fraction of Betel Nut (Areca catechu L.) in Colonic Goblet Cells of Mice (Mus musculus) Given Orally Infective Egg of Trichuris muris." Open Access Macedonian Journal of Medical Sciences 8, B (2020): 637–42. http://dx.doi.org/10.3889/oamjms.2020.4878.

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BACKGROUND: Trichuris trichiura is a soil-transmitted parasitic worm commonly found in humid, tropical to subtropical areas, as well as poor sanitation area. These worms are cosmopolitan, especially in tropical and humid countries like Indonesia. This worm infection is more common in developing countries and more in children than adults due to poorer child self-hygiene. Worm disease is one of the common society diseases with 60% of children in Indonesia which are estimated to be affected. One species of T. trichiura worm that is often used in research on experimental animals is Trichuris muris

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Christanto, Raymond, Andre Andre, Shania Foustine, and Leonny Yulita Hartiadi. "Combination of Piper betel Leaves and Areca catechu Nuts Ethanolic Extract Effects on In Vitro Antimicrobial Test against Aerobic Mouth Microbiota." Indonesian Journal of Life Sciences | ISSN: 2656-0682 (online) 1, no. 2 (2019): 48–53. http://dx.doi.org/10.54250/ijls.v1i2.24.

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Introduction: Oral health awareness in Indonesia is still low with more and more oral and/or dental infection becomes more prevalent such as gingivitis, endodontitis, and pericoronitis. These infections could be caused by mouth microflora such as lactobacilli, Streptococcus mutans, Streptococcus mitis, Streptococcus oralis, and Streptococcus sobrinus. As time goes by, these bacteria could also become more problematic as antibacterial resistance emerges. Betel nut and betel leaf are well known traditional herbs that is often used in combination for "nyirih"; an Indonesian tradition to chew both

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Chadijah, St, Sari Ningsih, Ummi Zahra, Syarifah Rabiatul Adawiah, and Iin Novianty. "Ekstraksi dan Uji Stabilitas Zat Warna Alami dari Biji Buah Pinang (Areca catechu L.) sebagai Bahan Pengganti Pewarna Sintetik pada Produk Minuman." KOVALEN: Jurnal Riset Kimia 7, no. 2 (2021): 137–45. http://dx.doi.org/10.22487/kovalen.2021.v7.i2.15541.

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Natural dyes are an alternative dye that is not toxic, environmentally, friendly and easily degraded. Therefore, optimizing the use of body coloring sources is carried out. One of the natural dyes released is tannin from betel nuts. Tannins are polar pigments. This study aims to determine the results of natural dyes in betel nuts and find out the durability produced and known organoleptic results. Dyestuff extraction from betel nuts was carried out with 96% ethanol. Testing the color stability of betel nut seedlings was carried out on the effect of pH, temperature and storage time with the met

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Sudipta, Chowdhury, and Nath Banerjee Samarendra. "Genotoxic activity of betel nut on germinal cell in Sarcoma 180 ascites tumour bearing male mice." GSC Biological and Pharmaceutical Sciences 16, no. 2 (2021): 172–81. https://doi.org/10.5281/zenodo.5285167.

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The genotoxicity of the ethanolic extract of betel nut was evaluated using sarcoma 180 tumour bearing mouse considering sperm motility, sperm viability, biochemical estimation of fructose in seminal fluid and sperm head morphology assays. Sperm head morphology was studied by H-E staining and Toluidine blue staining method. But Toluidine blue staining method is a reliable method to evaluate the DNA damage of sperms. Ethanolic BNE (betel nut extract) can suppress the percentage of sperm motility, sperm viability and seminal fructose level. In addition, it can also enhance the percentage of DNA d

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Tong, Ting, Aiqing Xu, Shuhua Tan, et al. "Biological Effects and Biomedical Applications of Areca Nut and Its Extract." Pharmaceuticals 17, no. 2 (2024): 228. http://dx.doi.org/10.3390/ph17020228.

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The dried, mature fruit of the palm tree species Areca catechu L. is known as the areca nut (AN) or betel nut. It is widely cultivated in the tropical regions. In many nations, AN is utilized for traditional herbal treatments or social activities. AN has historically been used to address various health issues, such as diarrhea, arthritis, dyspepsia, malaria, and so on. In this review, we have conducted a comprehensive summary of the biological effects and biomedical applications of AN and its extracts. Initially, we provided an overview of the constituents in AN extract. Subsequently, we summa

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Rahman, Ave Olivia, Erny Kusdiyah, Herlambang Herlambang, and Aldo Victoria. "UJI EFEK AFRODISIAK EKSTRAK BIJI PINANG MUDA (Areca Catechu L) PADA TIKUS JANTAN." JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" 8, no. 1 (2020): 34–39. http://dx.doi.org/10.22437/jmj.v8i1.9455.

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ABSTRACT Background: polyphenols and alkaloids in herbal plants could have aphrodisiac effect. Betel nut (Areca catechu L) contain polyphenol and alkaloid. Alkaloid of betel nut has aphrodisiac effect, but also has side effect to many organs. Data of aphrodisiac effect of betel nut’s polyphenols is limited. This study aim to determine aphrodisiac effect of extraction of betel nut’s polyphenols in rats Method: twelve rats, Sprague dawney, aged 2-3 months, weight 150-200 gram were divided into 2 group randomly. Group A were given the extract with doses 100mg/kgWB and group B were giv

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Sudipta Chowdhury and Samarendra Nath Banerjee. "Genotoxic activity of betel nut on germinal cell in Sarcoma 180 ascites tumour bearing male mice." GSC Biological and Pharmaceutical Sciences 16, no. 2 (2021): 171–81. http://dx.doi.org/10.30574/gscbps.2021.16.2.0235.

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The genotoxicity of the ethanolic extract of betel nut was evaluated using sarcoma 180 tumour bearing mouse considering sperm motility, sperm viability, biochemical estimation of fructose in seminal fluid and sperm head morphology assays. Sperm head morphology was studied by H-E staining and Toluidine blue staining method. But Toluidine blue staining method is a reliable method to evaluate the DNA damage of sperms. Ethanolic BNE (betel nut extract) can suppress the percentage of sperm motility, sperm viability and seminal fructose level. In addition, it can also enhance the percentage of DNA d

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Ayu Putu Swastini, I. Gusti Agung, I. Gusti Agung Ayu Dharmawati, Ni Nengah Sumerti, Tjokorda Gde Bagus Mahadewa, and I. Putu Eka Widyadharma. "The Difference Between Gargling Using Betel Nut Seed (Areca Catechu) Extract and Chlorhexidine 0.2% Solution in Chronic Gingivitis Healing." Biomedical and Pharmacology Journal 12, no. 2 (2019): 723–27. http://dx.doi.org/10.13005/bpj/1694.

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The use of mouthwash is an effective way to help cure gingivitis. Mouthwash that is often used is mouthwash containing antiseptic. Recently, there has been increasing use of traditional medicines that are considered safer such as areca nuts compared to chemically synthesized agents. The aim of this study was to calculate the difference in the healing of chronic gingivitis due to calculus between gargling using areca nut (Areca catechu) extract and using Chlorhexidine 0.2% solution. This was an experimental test with pre and post-test control group design and involved two treatment groups. A to

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Bali, Dr Sharadendu. "Paan – A Mouthful of Betel Leaf Packaged Ambrosia for Good Health." Scholars Journal of Applied Medical Sciences 13, no. 01 (2025): 104–29. https://doi.org/10.36347/sajb.2025.v13i01.012.

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The chewing of sachet-like betel leaf quids, packing various spicy and flavoured ingredients in a folded betel leaf, is a customary practise in a number of nations of South Asia. The betel leaf munchie (paan), most popularly chewed after meals, has been much berated and unfairly scorned, as it is thought to produce detrimental effects on the body. This dogma about the harmful effects of paan has been upended by recent studies demonstrating the beneficial impact of betel phytochemicals on several body functions, as well as on the gut microbiota. Moreover, the advantageous effects of the health-

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Putri, Aisy, Ica Yulianti Pulungan, and Olivia Des Vinca Albahana Napitupulu. "The effect of betel nut extract on melanin pigment levels in rats' skin exposed to Ultraviolet B radiation." Jurnal Prima Medika Sains 6, no. 1 (2024): 72–78. http://dx.doi.org/10.34012/jpms.v6i1.5454.

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This study aims to analyze the effect of areca nut extract on the amount of melanin pigment in the skin of Wistar rats exposed to ultraviolet-B light. The research method used was post-test with control group design. The total sample of white rats used was 20 rats, which were divided into 4 groups with each group consisting of 5 rats. The cream preparation was made using cold cream base. The rats were then exposed to UVB with a certain intensity for 5 days, characterized by erythema as a result of UVB absorption into the epidermis. Each group of treated rats received base cream, 10% areca nut

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Djohari, Meiriza, Wulandari Yulia Putri, and Erniza Pratiwi. "ISOLASI DAN UJI AKTIVITAS DAYA HAMBAT EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP BAKTERI PADA LIDAH." Jurnal Riset Kefarmasian Indonesia 1, no. 3 (2019): 177–88. http://dx.doi.org/10.33759/jrki.v1i3.57.

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Betel nut (Areca catechu L.) is a natural material that has antibacterial activity in treating diseased on teeth, halitosis and can inhibit of dental caries. The objective of this research is type of bacteria based on morphology, the results of bacterial identification tests on the tongue and to determine the effect of the inhibitory power of betel nut ethanol extract (Areca catechu L.) to bacteria of the tongue. Antibacterial activity testing using disc diffusion method with various concentrations of 10%, 20% and 30%. Secondary metabolite contents are alkaloid, terpenoid and flavonoid.The res

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Lilyawati, Sega Ade, Nurul Fitriani, and Fajar Prasetya. "Aktivitas Antimikroba Ekstrak Etanol Biji Pinang Muda (Areca catechu)." Proceeding of Mulawarman Pharmaceuticals Conferences 10 (October 31, 2019): 135–38. http://dx.doi.org/10.25026/mpc.v10i1.378.

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Thrush is an oral disease caused by bacterial and fungal infections. Treatment for this disease can be done by administering drugs that contain antimicrobial compounds. This study aims to test the ethanol extract of young areca nut against bacteria and fungi that cause Oral thrush. Young betel nut extract is obtained through maceration process using 96% ethanol. Then the activity of the Streptococcus sanguis bacteria and Candida albican fungus was tested. This test used the well method which was carried out on 5 variations of the concentration of young areca nut extract (2.5%; 5%; 7.5%; 10% an

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Lukito, Pradea Indah, Makhabbah Jamilatun, and Innaya Rahma Salsabila. "Antibacterial Activity Of Nginang Herb Extract Mouthwash Formulation Against The Streptococcus Mutans Bacteria." International Journal of Science and Environment (IJSE) 4, no. 2 (2024): 47–51. http://dx.doi.org/10.51601/ijse.v4i2.97.

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Nginang was chewing the raw green betel leaf combined with areca nut and gambier seeds, it was Indonesian people’s habit in ancient times to maintain the dental health. Over time, the nginang mixture was developed into a mouthwash formula to make it easier and acceptable to use. Mouthwash is a liquid form preparation with a pleasant taste and smell, to keep clean the mouth. The phytochemical content in the nginang herbs was tannin which is a phenolic compound. The mechanism of action of phenolics was by inactivated the microbial cell adhesion and to avoid the attached to host cells by the cell

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Rahman, Ave Olivia, and Humaryanto Humaryanto. "EFEK SALEP EKSTRAK PINANG TERHADAP LEVEL FIBROBLAST DAN KOLAGEN PADA PROSES PENYEMBUHAN LUKA." JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" 7, no. 1 (2019): 19–25. http://dx.doi.org/10.22437/jmj.v7i1.7121.

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ABSTRACT Background: Some plants, such as betel nuts (Areca catechu), is used as traditional antiseptic. Betel nut mash is applied on ulcus wound. Fibroblast and collagen are important factor in wound healing. Research objective : this study is to determine the effect of betel nuts extract on fibroblast and collagen level in full thickness wound healing processs. Methodology: this study used male rats Sprague dawney that randomly divided into 3 groups. Groups I received no treatment, groups II and III received areca catechu extracts with concentration 15% and 30% respectively. There are

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Fajar, Fajar Lestari, and Beny Rahmanto Beny. "The Plants Extract Toxicity Againts Achatina fulica (Ferussac, 1821) in Nyawai Ficus variegata (Blume)." Jurnal Wasian 7, no. 1 (2020): 39–50. http://dx.doi.org/10.62142/1ewcvx39.

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One of the problems in developing Nyawai plants is the attack of snail pests Achatina fulica (Ferussac, 1821) at seedling level of the plants. Plant damage caused by these pests is quite large and causes seedling death. One of the control efforts that can be done is utilizing biomaterials which have molluscicidal properties (can kill mollusks). This study aimed to determine the toxicity of some extracts of biomaterial to control Achatina fulica (Ferussac, 1821) pests. The research was conducted on a laboratory scale. The study used a factorial random design with 3 replications. The treatment c

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Koontongkaew, Sittichai, Boonyanit Thaweboon, and Rungsunn Tungtrongchitr. "The toxicity of betel nut extract determined by inhibition of microbial dehydrogenase activity." Toxicity Assessment 1, no. 4 (1986): 419–29. http://dx.doi.org/10.1002/tox.2540010404.

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Muhammad, Sultanaulya, Muhmammad Azdar Setiawan, Kemal Idris Balaka, and Ayu Astuti. "UJI EKSTRAK BIJI BUAH PINANG (Areca catechu L) SEBAGAI ALTERNATIF PEWARNAAN TELUR NEMATODA USUS SOIL TRANSMITED HELMINTH." Jurnal Analis Kesehatan Kendari 6, no. 2 (2024): 49–53. http://dx.doi.org/10.46356/jakk.v6i2.306.

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ABSTRACT Worm infection or can be called worm disease, including infection problems called parasitic infections. Soil transmited helmits are intestinal worms that in their life cycle to reach the infective stage require soil. Eosin 2% is a dye used in examination of intestinal nematode worm eggs. Areca (Areca catechu L) which is a natural and acidic plant material contains phobapheen compounds which have natural red wine color. This research was conducted in an Experiment with Variations in the concentration of betel nut extract and aqudest ( 1%, 2%, 3%) using the direct method using eosin 2%.

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A. Faden, Asma’a. "Evaluation of Antibacterial Activities of Aqueous and Methanolic Extracts of Areca catechu against Some Opportunistic Oral Bacteria." Biosciences, Biotechnology Research Asia 15, no. 3 (2018): 655–59. http://dx.doi.org/10.13005/bbra/2673.

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The aqueous and methanolic extracts of Areca catechu seeds (known as areca nut: a component of a betel quid, where their chewing habitis a popular cultural tradition in some South East Asian countries used as an oral cleanser) have shown some antimicrobial potentials against some oral bacteria which are capable of causing opportunistic infections in the mouth. The objective of this study is to detect the antibacterial activities of aqueous and methanolic extracts of Areca catechu against Escherichia coli and Staphylococcus aureus.Manystudies showed different antibacterial activity, depending o

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Bhattacharjee, Kasturi, Moumita Nath, and Yashmin Choudhury. "Berberine Mitigates Betel-Nut Induced Hepatocarcinogenesis, Enhances Chemosensitivity to Cisplatin and Reduces Cisplatin- Induced Nephrotoxicity in Mice Exposed to an Aqueous Extract of Betel Nut." Pharmacognosy Journal 16, no. 5 (2024): 1021–28. http://dx.doi.org/10.5530/pj.2024.16.165.

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Meutia Sari, Liza, Gus Permana Subita, and Elza Ibrahim Auerkari. "POTENTIAL ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF ARECA NUT (ARECA CATECHU LINN.) EXTRACT IN HUMAN ORAL SQUAMOUS CELL CARCINOMA AND KERATINOCYTE CELLS." Asian Journal of Pharmaceutical and Clinical Research 10, no. 10 (2017): 286. http://dx.doi.org/10.22159/ajpcr.2017.v10i10.20287.

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Objectives: Areca (betel, Areca catechu) nuts have been reported to show high contents of phenolic and flavonoid compounds with associated antioxidant activity. This study was undertaken to assess the anticancer potential of areca nut extract on human squamous carcinoma (HSC)-3, HSC-2, and human keratinocyte (HaCat) cancer cell lines, and to elucidate the mechanism of its action.Methods: In this study, the areca nut extract was prepared in 96% ethanol and analyzed for the total phenolic and flavonoid content, 2,2-diphenyl-1- picrylhydrazyl (DPPH) assay, and 5-(3-carboxymethoxyphenyl)-2-(4,5-di

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Lin, Shu-Chun, Suu-Yi Lu, Szu-Ying Lee, Chi-Yen Lin, Chun-Hsien Chen та Kuo-Wei Chang. "Areca (betel) nut extract activates mitogen-activated protein kinasesand NF-κB in oral keratinocytes". International Journal of Cancer 116, № 4 (2005): 526–35. http://dx.doi.org/10.1002/ijc.21104.

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Rusli Rustam and Ice S. Hutagalung. "¬UJI BEBERAPA KONSENTRASI BIJI PINANG (Areca catechu L.) UNTUK MENGENDALIKAN Helopeltis theivora." DINAMIKA PERTANIAN 37, no. 2 (2023): 141–48. http://dx.doi.org/10.25299/dp.2021.vol37(2).11867.

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Cocoa (Theobroma cacao L.) is a plantation commodity that plays an important role in Indonesia’s economic activities and is a potential foreign exchange earner. One of the biggest obstacles in growing cacao in Indonesia is the attack of the cocoa pod-sucking pests (Helopeltis theivora Waterhouse). The aim of this study is to obtain an effective concentration of betel nut to control the fruit-sucking pests (Helopeltis theivora Waterhouse) in cocoa plants in the laboratory. The research was conducted at the Plant Pest Laboratory and Experimental farm, Faculty of Agriculture, Riau University from

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Hsieh, Tusty-Jiuan, Pei-Chen Hsieh, Ming-Tsang Wu, et al. "Betel nut extract and arecoline block insulin signaling and lipid storage in 3T3-L1 adipocytes." Cell Biology and Toxicology 27, no. 6 (2011): 397–411. http://dx.doi.org/10.1007/s10565-011-9195-5.

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Panigrahi, G. B., and A. R. Rao. "Study of the genotoxicity of the total aqueous extract of betel nut and its tannin." Carcinogenesis 7, no. 1 (1986): 37–39. http://dx.doi.org/10.1093/carcin/7.1.37.

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Yang, Nai-Yen Jack, Krishna Kaphle, Pei-Hwa Wang, De-Shien Jong, Leang-Shin Wu, and Jen-Hsou Lin. "Effects of Aqueous Extracts of "Betel Quid" and Its Constituents on Testosterone Production by Dispersed Mouse Interstitial Cells." American Journal of Chinese Medicine 32, no. 05 (2004): 705–15. http://dx.doi.org/10.1142/s0192415x04002430.

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Betel quid (BQ) is a favorite chewing item among many communities in different parts of Asia where it is popular by different names. BQ is a unique combination of nut or fruit from the Areca catechu Linn. (AN) tree, leaf from the Piper betle Linn. (BL) vine, slaked lime, paste of bark from the Acacia catechu tree and other spices. AN has been used successfully in various traditional medicines by different civilizations over several ages. Initially condemned by the medical communities for its health hazards, identification and application of potent pharmacologically bioactive compounds from dif

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Dewi, Marzela, David Pakaya, and Joni Tandi. "Aktivitas Antischistosomiasis Sediaan Nanopartikel Ekstrak Biji Pinang pada Tikus Putih Jantan Terinfeksi Schistosoma japonicum." KOVALEN: Jurnal Riset Kimia 7, no. 1 (2021): 89–97. http://dx.doi.org/10.22487/kovalen.2021.v7.i1.15438.

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Schistosomiasis is a disease caused by Schistosoma japonicum worms and Oncomelania hupensis lindoensis as the intermediate snails. Praziquantel is a drug used to reduce the prevalence of schistosomiasis. However, its use has several side effects such as headaches, dizziness, nausea, vomiting as well as abdominal, joint, and muscle pain. The development of alternative drugs is a solution to reduce side effects. Betel (A. catechu) seeds are known to the public to have an anthelmintic effect because they contain alkaloids, tannins, flavan, phenolic compounds, as well as arecoline. To increase the

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Juswardi, Sinta Fitriani, Singgih Tri Wardana, Sarno, Syafrina Lamin, and Kamila Alawiyah. "Metabolite profiling of betel palm nuts (Areca catechu L.)." Open Access Research Journal of Biology and Pharmacy 12, no. 2 (2024): 034–49. https://doi.org/10.53022/oarjbp.2024.12.2.0039.

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The nuts of the betel palm (Areca catechu L.) are a valuable medicinal component due to their pharmacological effects and the presence of numerous bioactive metabolite compounds. To analyze the composition, abundance, and bioactivity of these metabolites, metabolite profiling was conducted using Gas Chromatography-Mass Spectrometry (GC-MS). The GC-MS analysis resulted in a chromatogram with 88 peaks, identifying 63 compounds, including four dominant ones, as well as other unknown metabolites, yielding a total metabolite compound abundance of 96.66%. The most abundant compound was arecoline (31

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Tari, Yusnia, Elsa Anggriani Sihombing, Maimum Maimum, et al. "INNOVATION OF DEODORANT STICKS AND LOTIONS BASED ON BETEL NUT EXTRACT AS AN ANTIBACTERIAL PROBLEM OF BODY ODOR AGAINST STAPHYLOCOCCUS AUREUS BACTERIA." Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) 6, no. 02 (2025): 169. https://doi.org/10.30587/herclips.v6i02.9625.

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Body odor is a common problem caused by the interaction between sweat and Staphylococcus aureus bacteria. Areca nut has potential as a pharmaceutical preparation because it contains secondary metabolite compounds such as alkaloids, flavonoids, tannins, saponins and polyphenols which have antibacterial properties. This research aims to extract areca nut seeds using the maceration method with 96% ethanol and formulate them into stick deodorant and lotion with a concentration of 5%. Physical properties tests were carried out to evaluate pH, homogeneity, spreadability, melting point and antibacter

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