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1

Pap, Ilona. "Productivity enhancement in optical semiconductor manufacturing: Early warning of failures in BHet laser fabrication." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/26736.

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There are unique challenges in the fabrication and testing of optical semiconductor devices because, unlike typical silicon semiconductor devices, which can be tested cost-effectively on the wafer, many optical devices can only be 'fully' tested once the individual die is bonded to a heat sink. As a result, both the manufacturing process and test strategy need to be capable of predicting yields and product quality attributes based on limited sampling from a batch of the product. The large number of product quality and process variables that are measured for each device when it is manufactured
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Bhat, Hilal [Verfasser], and Karl [Akademischer Betreuer] Lang. "Role of arenavirus therapy in melanoma / Hilal Bhat ; Betreuer: Karl Lang." Duisburg, 2021. http://d-nb.info/1227188072/34.

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3

Verhagen, Franciscus Johannes Josephus. "Toxicology of the food additives BHA and BHT." Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Maastricht University [Host], 1989. http://arno.unimaas.nl/show.cgi?fid=5479.

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Bhat, Gajanan S. "Stabilization of pan-based precursors for carbon fibers by Gajanan S. Bhat." Diss., Georgia Institute of Technology, 1990. http://hdl.handle.net/1853/10119.

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5

Bhat, Akshay [Verfasser]. "Bioinformatics modeling of proteomics changes in muscle invasive bladder cancer / Akshay Bhat." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2016. http://d-nb.info/1113011882/34.

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6

Weisberg, Ilan S. "Evaluation of common polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and betaine-homocysteine methyltransferase (BHMT)." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0032/MQ64479.pdf.

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7

Mercer, Carol A. "Structural and Signaling Elements Important for the Efficient Degradation of BHMT through Macroautophagy." Wright State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=wright1176234559.

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8

Bhat, Shruti S. [Verfasser], and Markus [Akademischer Betreuer] Hoth. "Functions of Syntaxin 8 in human cytotoxic T lymphocytes / Shruti S. Bhat. Betreuer: Markus Hoth." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2014. http://d-nb.info/1053983433/34.

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9

Bhat, Anayat [Verfasser]. "Live Cell Fluorescence Imaging of Nucleotide Dynamics : ATP Hydrolysis and DNA Damage Response / Anayat Bhat." Konstanz : KOPS Universität Konstanz, 2021. http://d-nb.info/1229351094/34.

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10

Bhat, Jaydeep [Verfasser], Thomas [Akademischer Betreuer] Bosch та Dietrich [Gutachter] Kabelitz. "Epigenetic analysis of human γδ T lymphocytes / Jaydeep Bhat ; Gutachter: Dietrich Kabelitz ; Betreuer: Thomas Bosch". Kiel : Universitätsbibliothek Kiel, 2017. http://nbn-resolving.de/urn:nbn:de:gbv:8-diss-205915.

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Bhat, Avinash Shashidhar [Verfasser], and Michael [Akademischer Betreuer] Mastalerz. "Accessing chemically robust amide cages via the Pinnick oxidation / Avinash Shashidhar Bhat ; Betreuer: Michael Mastalerz." Heidelberg : Universitätsbibliothek Heidelberg, 2021. http://d-nb.info/1236345487/34.

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Borges, Ãngela da Silva. "Uso de compostos extraÃdos da manga (Mangifera indicus) no controle da oxidaÃÃo lipÃdica na carne de frango, em produto cÃrneo tipo mortadela e ovos de consumo." Universidade Federal do CearÃ, 2009. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=6057.

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FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>O presente trabalho teve como objetivos avaliar o efeito da inclusÃo de antioxidantes naturais da manga na raÃÃo de frangos de corte e de poedeiras comerciais sobre a estabilidade oxidativa da carne de frango, produto cÃrneo tipo mortadela, bem como dos ovos de consumo. Foram preparados dois extratos etanÃlicos com a casca (E1) e o caroÃo (E2) da manga. Os extratos desidratados foram utilizados em dois ensaios biolÃgicos: um com frangos de corte e outro com poedeiras comercias. Em ambos os ensaios os tratamentos alimenta
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Gürtler, Nora [Verfasser]. "Asymptotische Untersuchungen zur Klasse der BHEP-Tests auf multivariate Normalverteilung mit festem und variablem Glättungsparameter / Nora Gürtler." Karlsruhe : KIT-Bibliothek, 2000. http://d-nb.info/1013896866/34.

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14

Bojesen, Christine K. "Assessing the Effects of Bio-identical Hormone Replacement Therapy Using the Menopause Rating Scale." The University of Arizona, 2008. http://hdl.handle.net/10150/624277.

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Class of 2008 Abstract<br>Objectives: The purpose of this study was to assess the effects of using compounded Bio-identical Hormone Replacement Therapy (BHRT) in menopausal women, by employing the MRS. Methods: This study used a one group pre-test/ post-test. Included were 25 menopausal women, whom at initial BHRT consultation at Reed’s Compounding Pharmacy filled out a baseline menopausal rating scale (MRS). Eleven weeks into therapy, patients were asked to participate in this study and if interest was expressed, they were asked to fill out another MRS for comparison. Results: There was a s
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15

Häner, Robert. "Erzeugung von Ketenen aus BHT-Esterenolaten sowie Metallierung von Cyclopropan- und Aziridin-2-carbonsäurederivaten /." [S.l.] : [s.n.], 1987. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=8265.

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Wiginton, John Franklin. "Instrumental laboratories based on the analysis of butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) /." Full text available from ProQuest UM Digital Dissertations, 2008. http://0-proquest.umi.com.umiss.lib.olemiss.edu/pqdweb?index=0&did=1850457291&SrchMode=1&sid=1&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1279301048&clientId=22256.

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17

Wajman, Michal. "Technical and Economical Analysis of Ground Source Heat Pump Systems with BHE in Poland." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-33642.

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Nowadays, Ground Source Heat Pumps (GSHPs) are more frequently acting as a main or the only device covering the building heat/cool demand. The most efficient way to extract/dissipate the low-temperature heat from/to the ground is by means of Borehole Heat Exchanger (BHE). In this Master of Science Thesis various aspects related to this technology are studied, focused on summarizing the possibilities of installing this tech-nology in Poland. Borehole drilling methods used in Poland and Sweden are analyzed and the most proper and economical ones according to Polish geological structure are propo
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Kertzscher, Jana. "2. Freiberger Kolloquium Elektrische Antriebstechnik: Kolloquium im Rahmen des 70. BHT - Freiberger Universitätsforum 2019." Technische Universität Bergakademie Freiberg, 2019. https://tubaf.qucosa.de/id/qucosa%3A38447.

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Vom 6.6. bis 7.6.2019 fand das 2. Freiberger Kolloquium Elektrische Antriebstechnik (FKEA) im Rahmen des 70. BHT statt. Schwerpunkte sind die Modellierung und Simulation von elektrischen Maschinen, thermische Untersuchungen, Auslegung und Fertigung neuer Motorenkonzepte sowie Traktionsspeicher.
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Kertzscher, Jana. "3. Freiberger Kolloquium Elektrische Antriebstechnik: Kolloquium im Rahmen des 72. BHT - Freiberger Universitätsforum 2021." Technische Universität Bergakademie Freiberg, 2021. https://tubaf.qucosa.de/id/qucosa%3A75538.

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Dieser Konferenzband stellt alle schriftlich eingereichten Beiträge zum 3. Freiberger Kolloquium Elektrische Antriebstechnik zusammen. Thematische Schwerpunkte waren 2021: Modellierung und Simulation von elektrischen Maschinen und Antrieben, Auslegung und Fertigung neuer Motorenkonzepte, Thermische Untersuchungen an elektrischen Maschinen, Regelung elektrischer Maschinen, Ladetechnologien für Elektrofahrzeuge, Theoretische Elektrodynamik von Traktionsantrieben
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Tran, Amy V. "Do BHA and BHT Induce Morphological Changes and DNA Double-Strand Breaks in Schizosaccharomyces pombe?" Scholarship @ Claremont, 2013. http://scholarship.claremont.edu/scripps_theses/152.

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Butylated Hydroxyanisole, BHA, and Butylated Hydroxytoluene, BHT, are commonly used as preservatives for our food as well as additives in many products such as cosmetics, petroleum, and medicine. Although their use has been approved by the Food and Drug Administration (FDA), there have been controversies and debates on whether these phenol derivatives or antioxidants are safe to use. Their accumulative toxicology and side effects need to be thoroughly investigated as we continue to consume them on a daily basis. Data obtained by genomic analysis in Tang lab suggested the involvement of DNA dam
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Martins, Marli Cardoso. "Resposta cardiovascular a noradrenalina e ao BHT-920 em ratos submetidos aos "stress" por natação." [s.n.], 1991. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314612.

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Orientador: Regina Celia Spadari<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-14T00:03:56Z (GMT). No. of bitstreams: 1 Martins_MarliCardoso_M.pdf: 3221775 bytes, checksum: 809e499c474fa4c62483d771cca4381d (MD5) Previous issue date: 1991<br>Resumo: Estudos prévios demonstraram que átrios direitos isolados de ratos submetidos ao "stress" apresentam alterações de sensibilidade ao efeito cronotrópico das catecolaminas. Os objetivos deste trabalho são: avaliar a possibilidade de uitilização da técnica de registro da pr
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Paradis, Alexandre. "Implication des récepteurs de type Toll dans la migration des monocytes via la modulation du récepteur CCR7." Mémoire, Université de Sherbrooke, 2015. http://hdl.handle.net/11143/8071.

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Notre laboratoire a démontré que le récepteur de chimiokine CCR7 joue un rôle majeur dans la migration des monocytes en réponse à ses ligands naturels, les chimiokines CCL19 et CCL21. Plusieurs études ont permis de mettre en évidence que les monocytes en réponse à des infections, des traumatismes ou des maladies neurologiques, migrent vers les tissus en inflammation du cerveau par un mécanisme jusqu’à présent inconnu. D’un autre côté, l’activation de certains récepteurs TLR (de l’anglais « Toll-like receptors ») par des composants bactériens est caractéristique aux infections bactériennes et t
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Leblanc, David. "Les monocytes CCR7+ comme outil de transport des nanoantirétroviraux vers le système nerveux central." Mémoire, Université de Sherbrooke, 2015. http://hdl.handle.net/11143/6774.

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Actuellement, l'infection au virus de l'immunodéficience humaine de type 1 (VIH-1) est considérée comme une infection chronique contrôlable à moyen et long terme. En effet, l'utilisation appropriée de combinaisons d'antirétroviraux ainsi qu'un suivi du développement de la résistance chez le virus peut diminuer la charge virale pendant des décennies et retarder l'apparition du syndrome d'immunodéficience acquise (SIDA). Cependant, certains de ces médicaments, et tout particulièrement les inhibiteurs de protéase du VIH-1 pénètrent difficilement dans certains organes pouvant servir de réservoirs
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Kertzscher, Jana. "Freiberger Kolloquium Elektrische Antriebstechnik: 68. BHT - Freiberger Universitätsforum : Herrn Prof. Dr.-Ing. habil. Ulrich Beckert zum 75. Geburtstag gewidmet." Technische Universität Bergakademie Freiberg, 2017. https://tubaf.qucosa.de/id/qucosa%3A36174.

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Vom 8.6. bis 9.6.2017 fand im Rahmen des BHT das Fachkolloquium Elektrische Antriebstechnik statt. Das Freiherger Kolloquium Elektrische Antriebstechnik umfasst den Themenkreis elektrische Maschinen, elektrische Antriebe und Energiespeicher. Dabei sind Modellierung und Simulation von elektrischen Maschinen und Antrieben, Auslegung neuer Motorenkonzepte, thermische Untersuchungen an elektrischen Maschinen und Alterung der Energiespeicher die thematischen Schwerpunkte der Veranstaltung. Der Kolloquiumsband ist Herrn Prof. Dr.-Ing. habil. Ulrich Beckert zu semem 75. Geburtstag gewidmet.
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Bhat, Shrikant [Verfasser], Ralf [Akademischer Betreuer] Riedel, and Hans-Joachim [Akademischer Betreuer] Kleebe. "Studies on Boron-Carbon-Nitrides (B-C-N) Leading to the Discovery of the Novel Boron Oxynitride B6N4O3 / Shrikant Bhat. Betreuer: Ralf Riedel ; Hans-Joachim Kleebe." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2016. http://d-nb.info/1112269614/34.

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Araujo, Endrigo Adonis Braga de [UNESP]. "Efeito da adição de butil-hidroxitolueno nos meios de refrigeração e congelação sobre a viabilidade espermática de equinos." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/138123.

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Submitted by ENDRIGO ADONIS BRAGA DE ARAUJO null (adonis.tecvet@yahoo.com.br) on 2016-04-27T02:07:05Z No. of bitstreams: 1 DISSERTAÇÃO_BHT_Araujo, EAB.pdf: 638286 bytes, checksum: 01feb4c9fddef023795b0f62318b20f2 (MD5)<br>Approved for entry into archive by Felipe Augusto Arakaki (arakaki@reitoria.unesp.br) on 2016-04-28T16:16:58Z (GMT) No. of bitstreams: 1 araujo_eab_me_bot.pdf: 638286 bytes, checksum: 01feb4c9fddef023795b0f62318b20f2 (MD5)<br>Made available in DSpace on 2016-04-28T16:16:58Z (GMT). No. of bitstreams: 1 araujo_eab_me_bot.pdf: 638286 bytes, checksum: 01feb4c9fddef023795b0f62
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Araujo, Endrigo Adonis Braga de. "Efeito da adição de butil-hidroxitolueno nos meios de refrigeração e congelação sobre a viabilidade espermática de equinos." Botucatu, 2016. http://hdl.handle.net/11449/138123.

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Orientador: Frederico Ozanam Papa<br>Resumo: O processo de criopreservação acarreta estresse oxidativo à célula espermática e a adição de antioxidantes aos meios de refrigeração e congelação de sêmen pode auxiliar na proteção dos espermatozoides contra o dano induzido pelas espécies reativas de oxigênio (ERO), incluindo perda da motilidade de forma irreversível, peroxidação lipídica e fragmentação do DNA, interferindo na capacidade de fertilização do espermatozoide. Dentre os diferentes antioxidantes, o Butil-hidroxitolueno (BHT) é um análogo sintético da vitamina E, cujo efeito protetor é atr
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Iglebaek, Herceglija Ena. "Stability testing of all-trans-retinol in an experimental cosmetic formulation and in methanol and methanol containing butylhydroxytoluene (BHT) using reversed-phase HPLC." Thesis, KTH, Kemi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-302695.

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All-trans-retinol (vitamin A) används ofta som en aktiv ingrediens i kosmetiska produkter på grund av dess kliniskt validerade anti-age-egenskaper. Däremot är användningen av all-trans-retinol i kosmetiska formuleringar begränsad till följd av den kemiska stabiliteten av all-trans-retinol som påverkas av värme, syre, ljus och syror. Både kompositionen av en kosmetisk formulering, samt lagringsförhållanden och förpackningen av produkten, kan påverka nedbrytningen av all-trans-retinol till mindre aktiva former.  I denna studie har stabilitetstestning genomförts under två månader i syfte att utvä
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Mysiorek, Caroline. "La barrière hémato-encéphalique et l'ischémie cérébrale : étude in vitro de la dysfonction et de la protection microvasculaire." Thesis, Artois, 2009. http://www.theses.fr/2009ARTO0403/document.

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La barrière hémato-encéphalique (BHE) est une interface localisée au niveau des cellules endothéliales des capillaires cérébraux. Elle présente des caractéristiques physiques et métaboliques spécifiques restreignant les échanges entre le sang et le cerveau dans le but de maintenir l’homéostasie du système nerveux central. Dans des conditions pathologiques comme l’ischémie cérébrale, la perte de son intégrité provoque l’apparition d’un oedème vasogénique qui aggrave considérablement le pronostic vital des patients. Malheureusement, les mécanismes impliqués dans l’hyperperméabilité vasculaire de
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Gregg, Alison Dianne. "The design and synthesis of potential dual action cardioprotective agents acting at adenosine receptors." Queensland University of Technology, 2006. http://eprints.qut.edu.au/16629/.

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Adenosine and adenosine analogues are recognised as cardioprotective agents due to the responses that they induce through the activation of myocardial adenosine receptors. Antioxidants such as nitroxide radicals have also been found to possess cardioprotective properties in biological systems, namely through their ability to scavenge the oxygen-based free radicals that are potentially damaging to tissues and cells. It was envisaged that the linking of an antioxidant moiety to adenosine would produce an adenosine analogue that activates adenosine receptors and also scavenges oxygen-derived fre
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Gondim, Amanda Duarte. "Avalia??o da estabilidade t?rmica e oxidativa do biodiesel de algod?o e do efeito da adi??o de antioxidantes (α-tocoferol e BHT)." Universidade Federal do Rio Grande do Norte, 2009. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17703.

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Made available in DSpace on 2014-12-17T15:42:06Z (GMT). No. of bitstreams: 1 AmandaDG.pdf: 3418517 bytes, checksum: 8b4c45093282af02fba617928f13a7de (MD5) Previous issue date: 2009-03-20<br>Petr?leo Brasileiro SA - PETROBRAS<br>This work aims to study the effects of adding antioxidants, such as, &#945;- tocopherol and BHT on the thermal and oxidative stability of biodiesel from cottonseed (B100). The Biodiesel was obtained through the methylical and ethylical routes. The main physical and chemical properties of cotton seed oil and the B100 were determined and characterized by FTIR and GC. Th
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Gomes, Tarsila Daysy Ursula Hermogenes. "Efeito da concentração de metionina na dieta durante o período pré e pósnatal sobre o estresse oxidativo, a instabilidade genômica e expressão de RNAm de Mat1a, Bhmt e Cbs em camundongos." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/60/60134/tde-10022014-143246/.

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A metionina é doadora de grupos metil para metilação do DNA, processo responsável por modificações da expressão gênica. Diante da importância da metionina para o crescimento e desenvolvimento normais, variações desse aminoácido na dieta podem alterar a estabilidade do DNA. O objetivo desse trabalho foi avaliar o efeito de dietas deficiente e suplementada em metionina sobre a instabilidade genômica e o estresse oxidativo em camundongos e suas mães tratadas durante gestação e lactação e destas também foi realizada a expressão de RNAm de Mat1a, Bhmt e Cbsdas vias de transmetilação, remetilação e
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Maxwell, Sheena, and sheenamax@optusnet com au. "An assesssment of non-conventional measures of lung function and the effedt of a herbal extract on mild-moderate childhood asthma." RMIT University. Health Sciences, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080507.150547.

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Background: Respiratory conditions are prevalent and cause an enormous burden on society. In recent decades, there has been a global increase in asthma in children and adults, yet the diagnosis of asthma must be made on clinical grounds as the diagnostic use of pharmacological reversibility of airway obstruction remains controversial. It is possible however that tools exist from different medical paradigms that may assist in the clinical diagnosis of asthma. Tools such as Traditional Chinese Medicine (TCM) enquiry, Breath Holding Time (BHT) or Electro-Dermal Screening Test (EDST) may provid
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Kirker, Grant Terral. "Effects of chlorothalonil (CTN) and butylated hydroxy-toluene (BHT) on microbial communities involved in the deterioration of wood using terminal restriction fragment length polymorphism (T-RFLP) analyses." Diss., Mississippi State : Mississippi State University, 2008. http://library.msstate.edu/etd/show.asp?etd=etd-04022008-155301.

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Saint-Pol, Julien. "Liver X Receptors (LXRs), agonistes et gènes cibles : implication dans le transport des peptides ß-amyloïdes par les cellules endothéliales et les péricytes de la barrière hémato-encéphalique." Thesis, Artois, 2013. http://www.theses.fr/2013ARTO0402.

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Depuis le début du XXIème siècle, de nombreuses études ont souligné les relations étroites existant entre la voie des récepteurs nucléaires Liver X Receptors (LXRs), leurs gènes cibles et la maladie d'Alzheimer (MA). La stimulation de cette voie est considérée par conséquent comme une approche thérapeutique prometteuse. Cette voie régule de manière complexe et précise l'homéostasie cérébrale du cholestérol et le métabolisme des peptides β-amyloïde (Aβ). Les effets des oxystérols (produits de l'autoxydation du cholestérol) tels que le 24S-hydroxycholestérol (24S-PH-chol) et le 27-hydroxycholest
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Romano, Dario. "Influence of catalytic systems on the synthesis of (dis)entangled UHMWPE and its implications on mechanical properties." Thesis, Loughborough University, 2014. https://dspace.lboro.ac.uk/2134/14446.

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Two different catalysts (bis[N-(3-tert-butylsalicylidene)-pentafluoroanilinato] titanium (IV) dichloride and [1-(8-quinolyl)indenyl] chromium (III) dichloride catalysts) activated with aluminoxane based co-catalysts (MAO, PMAO, MMAO12 and MMAO3A) have been evaluated in the polymerisation of ethylene leading to UHMWPE having a reduced number of entanglements between the chains. The effect of a co-catalyst modifier (BHT) on the catalytic systems and the resulting polymers is also addressed. Both catalysts are capable to promote the synthesis of UHMWPE having a reduced amount of entanglements in
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Reed, Gail L. "Fast GC: Applications and Theoretical Studies." Diss., Virginia Tech, 1999. http://hdl.handle.net/10919/29085.

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Experimental data are presented for the first time in support of a theoretical model of band broadening proposed by Blumberg (1997). This model addresses the effects of the compressibility of the mobile phase in gas chromatography and presents an equation derived from only two mutually independent variables. Solutions of decane and tridecane in hexane were analyzed at pressures ranging from 15 to 150 psi. Six different columns were used that varied in length, internal diameter and film thickness. Theoretical plate heights were obtained from this data and plotted versus the average linear c
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Ball, Kathryn. "Physiologically based pharmacokinetic modelling of the central nervous system : strategies for drug development." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05P630.

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Une étape critique au cours du développement de médicaments est la mesure ou la prédiction des concentrations du médicament dans un tissu cible, qui peuvent ensuite être liées à des mesures de leur efficacité ou leur toxicité. Les concentrations de médicaments ne pouvant être mesurées dans le cerveau humain, ils doivent être simulés ou prédits en utilisant des approches alternatives de modélisation. L'objectif de cette thèse est de développer in silico des approches de prédiction combinant à la fois des données précliniques in vitro et in vivo dans un modèle physiologique structuré, avec une s
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Thiebaut, Nicolene Magrietha. "Statistical properties of forward selection regression estimators." Diss., University of Pretoria, 2011. http://hdl.handle.net/2263/29520.

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Santos, Francisco Francielle Pinheiro dos. "AvaliaÃÃo de antioxidantes aplicados à produÃÃo de biodiesel." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=10400.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>Este trabalho apresenta um estudo do comportamento e eficÃcia de antioxidantes aditivados ao biodiesel do Ãleo de soja. Os antioxidantes mais utilizados sÃo de estrutura fenÃlica, deste modo, sintetizar, comparar e estudar a aÃÃo destes antioxidantes avaliando as possÃveis causas que os levam a serem mais eficazes traz-nos informaÃÃes para a sÃntese de compostos com melhor atuaÃÃo antioxidante. Para uso como substrato orgÃnico, foi sintetizado o biodiesel a partir do Ãleo de soja, uma vez que à a partir deste, a produÃÃo de 81 % do
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Varini, Karine. "Trafic intracellulaire de peptide-vecteurs ciblant le récepteur au LDL pour des stratégies de délivrance ciblée d'agents thérapeutiques ou d'imagerie à travers la barrière hémato-encéphalique." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5023.

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La plupart des médicaments développés pour les maladies du SNC n’atteignent pas leur cible en raison des propriétés uniques de la BHE, nécessitant la mise en place de stratégies de délivrance comme l'utilisation d'un processus physiologique, le RMT. Des peptides ciblant le LDLR (exprimé à la BHE et impliqué dans ces processus) ont été développés. Les objectifs de cette thèse ont été de caractériser le trafic intracellulaire et la capacité de transport de différentes formes de ces peptides dans différents modèles in vitro y compris dans un modèle de BHE.Les résultats obtenus dans une lignée cel
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Bonnet, Amandine. "Etudes de trois métalloprotéases matricielles, MT1-MMP, MT5-MMP et MMP-12 dans l'amyloïdogenèse et les atteintes inflammatoires et vasculaires associées à la maladie d'Alzheimer." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0036.

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La maladie d’Alzheimer (MA) est la maladie neurodégénérative la plus commune et reste à ce jour incurable. Elle se caractérise par l’accumulation dans le cerveau du peptide neurotoxique bêta-amyloïde (Aβ), par une neuroinflammation et des atteintes neurovasculaires, qui ensemble induisent la mort des neurones et des déficits cognitifs. En raison de leurs activités multiples, les métalloprotéases matricielles (MMPs) émergent comme des acteurs importants dans la MA. Mes travaux ont permis de mieux comprendre l’implication de 3 de ces MMPs dans la MA et soulignent le caractère spécifique et compl
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Dalla, Santa Giorgia. "Effetti sulle proprietà meccaniche, idrauliche e termiche prodotti da scambiatori geotermici nei terreni argillosi: il caso studio della città di Venezia." Doctoral thesis, Università degli studi di Padova, 2016. http://hdl.handle.net/11577/3425232.

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In Ground Source Heat Pump systems (GSHP) a continuous circulation of a fluid inside the exchangers installed in the ground transfers heat between the ground and the building’s conditioning system. The heat exchange connected to a GSHP has been shown to alter the natural thermal status of the surrounding subsoil (Banks, 2012). Often the carrier fluids are brines consisting of a mixture of water and anti-freezing solutions, which lower their working temperature in order to improve the heat extraction from the ground during the cold season. The international community has already pointed out t
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Denker, Richard. "Dimensioning and control for heat pump systems using a combination of vertical and horizontal ground-coupled heat exchangers." Thesis, Karlstads universitet, Institutionen för ingenjörsvetenskap och fysik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-36475.

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A model has been developed which simulates a system consisting of a horizontal and vertical ground-coupled heat exchanger connected in parallel to the same heat pump. The model was used in computer simulations to investigate how the annual minimum and mean fluid temperatures at the heat pump varied as several parameters of the combined system were changed. A comparison was also made between different control settings for fluid flow rate distribution between the two exchangers. For the case when the flow rate distribution was not controlled, the effect of viscosity differences between a colder
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Richardot, Thomas. "Développement d'un matériau piézoélectrique sans plomb pour la réalisation de sondes ultrasonores haute fréquence." Thesis, Tours, 2016. http://www.theses.fr/2016TOUR4011/document.

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L’échographie haute résolution est une technique d’imagerie médicale permettant une observation du corps de très bonne définition, à faible profondeur (quelques micromètres). Pour réaliser cela, des ondes ultrasonores sont utilisées (quelques dizaines de mégahertz), produites par l’élément actif de la sonde: un film piézoélectrique. Pour atteindre de telles fréquences, cet élément doit être d’une épaisseur déterminée: de l’ordre de la dizaine de micromètres. Aujourd’hui, le PZT, zirconotitanate de plomb, est le matériau piézoélectrique démontrant les meilleures propriétés pour de telles applic
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Borin, Diego Becker. "EFEITO ANTIOXIDANTE DE LIPOSSOMAS CONTENDO CREATINA NO PROCESSO DE ISQUEMIA/REPERFUSÃO CEREBRAL EM RATOS: DESENVOLVIMENTO, CARACTERIZAÇÃO E AVALIAÇÃO FARMACOLÓGICA." Universidade Franciscana, 2013. http://tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/206.

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Made available in DSpace on 2018-06-27T18:56:03Z (GMT). No. of bitstreams: 3 Diego Becker Borin.pdf: 1553948 bytes, checksum: b94d052c85f74f3bcc5e4cadbcb71e67 (MD5) Diego Becker Borin.pdf.txt: 134530 bytes, checksum: f3ad94a2052d1806ff21e9c0ce7733fb (MD5) Diego Becker Borin.pdf.jpg: 3538 bytes, checksum: b4b8b2603cafaeb4736f56efe30f7f1d (MD5) Previous issue date: 2013-03-26<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Creatine is a biomolecule endogenously synthesized from amino acids which can also be obtained through the diet. But it does not permeate easily through th
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Drolez, Aurore. "Métastases cérébrales des cellules du cancer du sein : étude in vitro des mécanismes responsables du passage au travers de la Barrière Hémato Encéphalique." Thesis, Artois, 2016. http://www.theses.fr/2016ARTO0404/document.

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Dans le monde, une femme sur neuf sera atteinte d’un cancer du sein et environ un tiers développeront alors des métastases, principalement au niveau des poumons, des os et du cerveau. Dans ce dernier cas, le pronostic de survie des patientes est extrêmement faible, et ce, malgré le développement constant de nouvelles molécules anticancéreuses. En effet, la majorité de ces composés sont inefficaces du fait de leur incapacité à franchir la barrière hémato-encéphalique (BHE) pour aller cibler les métastases cérébrales. Ainsi, bloquer le passage des cellules tumorales vers l’endothélium cérébral p
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Previdelli, Ágatha Nogueira. "Padrões da dieta de adolescentes do município de São Paulo e fatores associados: estudo de base populacional." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/6/6138/tde-02042013-092319/.

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Introdução: Padrões alimentares estabelecidos na adolescência têm sido associados a fatores de risco para o desenvolvimento de doenças crônicas, tais como diabetes, doenças cardiovasculares e câncer. Objetivo: Avaliar os padrões da dieta de adolescentes e seus fatores associados. Metodologia: Utilizaram-se dados de adolescentes provenientes do estudo de base populacional do município de São Paulo. Foram utilizadas duas abordagens distintas na identificação dos padrões da dieta: o Índice de Qualidade da Dieta Revisado (IQD-R) e a análise fatorial. Para estimar a ingestão usual, foram coletados
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Westin, Rasmus. "Värmeöverföring i bergvärmesystem : En numerisk analys av den ringformade koaxiala borrhålsvärmeväxlaren." Thesis, Uppsala universitet, Elektricitetslära, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-176915.

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The borehole heat exchangers of today suffer from poor thermal and hydrodynamic performance. The purpose of this thesis is to improve the performance of ground source heat pump systems and thermal energy storages by increasing the energy efficiency of the borehole heat exchangers. For this reason, the annular coaxial borehole heat exchanger (CBHE) has been analyzed. This type of heat exchanger is interesting in terms of both thermal and hydrodynamic performance. A model has been set up in the program Comsol Multiphysics in order to investigate the heat transfer characteristics along the boreho
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Silva, Lidia Maria Rebolho Batista. "Variantes genéticas envolvidas no metabolismo do folato: impacto na carcinogênese de cabeça e pescoço." Faculdade de Medicina de São José do Rio Preto, 2010. http://bdtd.famerp.br/handle/tede/191.

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Made available in DSpace on 2016-01-26T12:51:46Z (GMT). No. of bitstreams: 1 lidiamariarbatistadasilva_dissert.pdf: 704096 bytes, checksum: f7be6357fe128cc459a3a697cab13d68 (MD5) Previous issue date: 2010-12-07<br>Introduction: Head and neck cancer is a collective term defined by anatomical and topographical basis to describe malignant tumors of the upper aerodigestive tract. This anatomical region includes the oral cavity, pharynx and larynx, having as the main risk factors smoking and alcoholism. The most representative hystologic type from head and neck cancer was squamous cell carcinoma
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