Academic literature on the topic 'Bible. O.T. Numbers'

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Journal articles on the topic "Bible. O.T. Numbers"

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Huang, Wenting, Kritika Kachapati, David Adams, Yuehong Wu, Patrick Leung, Guo-Xiang Yang, Weici Zhang, et al. "Murine autoimmune cholangitis requires two hits: cytotoxic KLRG1+ CD8 effector cells and defective T regulatory cells (BA13P.122)." Journal of Immunology 192, no. 1_Supplement (May 1, 2014): 177.8. http://dx.doi.org/10.4049/jimmunol.192.supp.177.8.

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Abstract Primary biliary cirrhosis (PBC) is an enigmatic disease mediated by autoimmune destruction of cholangiocytes in hepatic bile ducts. Early immunological events in PBC are poorly understood; clinical signs of disease occur very late in the pathological process. We have used our unique murine model of PBC in dominant-negative TGF-β receptor type II transgenic mice to delineate critical early immunopathological pathways, and previously showed that dnTGFβRII CD8 T cells alone transfer biliary disease. Herein we report significantly increased numbers of hepatic terminally differentiated (KLRG1+) CD8 T cells in dnTGFβRII compared to B6; these cells are the major cytotoxic CD8 subset. Unexpectedly, the disease is not simply CD8 T cell intrinsic since mixed bone marrow chimeric mice were protected from biliary disease. Adoptive transfer studies showed that co-transfer of B6 but not dnTGFβRII Tregs prevented dnTGFβRII CD8 T cell mediated cholangitis; the protection was associated with decreased numbers of hepatic KLRG1+ CD8 T cells and with elimination of hepatic dnTGFβRII CD8 mediated cholangiocyte cytotoxicity. DnTGFβRII Treg cells were inferior in suppressing effector CD8 T cells in vitro compared to wild type B6 Tregs. In conclusion, these results emphasize that autoimmune cholangitis requires defects in both the T effector and regulatory compartments, which has important implications for understanding the early pathogenesis of human PBC.
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Tucker, Rebecca, Ronald Gill, and Cara Mack. "Generation of T-cell Hybridomas Specific for Bile Duct and Rhesus Rotavirus Antigens in a Murine Model of Biliary Atresia (130.27)." Journal of Immunology 178, no. 1_Supplement (April 1, 2007): S233. http://dx.doi.org/10.4049/jimmunol.178.supp.130.27.

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Abstract Rhesus rotavirus (RRV)-inoculated neonatal BALB/c mice develop an immune mediated inflamation of both extra- and intraheptatic bile ducts which progresses to biliary obstruction and death by 3 weeks of age. The livers of diseased animals demonstrate increased numbers of T-lymphocytes along with elevated expression of Th1 type cytokines at both one and two weeks. Previous work in our laboratory has demonstrated that the liver infiltrating T-lymphocytes are both RRV-reactive and autoreactive to bile duct antigens. In addition, transfer of T-cells from diseased animals leads to inflamation of bile ducts in SCID mice. This inflamation occurs in the absence of virus, suggesting that bile duct antigens alone are capable of soliciting this response. In order to identify the antigens being targeted, and to determine if the autoreactivity arises via an epitope spreading or molecular mimicry mechanism, we have generated T-cell hybridomas from the livers of 2 week old diseased mice. Initial analysis of these hybridomas reveals four classes of hybridomas. TCR positive but non-reactive to tested antigens,RRV-specific,bile duct-specific, anddual reactive to both RRV and bile duct antigens. Further study of these hybridomas should clarify what mechanism is occuring and assist in identification of autoantigens.
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Tucker, Rebecca, Stephen Brindley, and Cara Mack. "Regulatory T cell perturbation in biliary atresia (115.4)." Journal of Immunology 186, no. 1_Supplement (April 1, 2011): 115.4. http://dx.doi.org/10.4049/jimmunol.186.supp.115.4.

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Abstract Biliary atresia (BA) is an inflammatory disease of the biliary system which leads to cirrhosis and the need for liver transplantation in the majority of children. The etiology of BA is unknown and one theory is that bile duct injury is due to a virus-induced, subsequent autoreactive T cell-mediated inflammatory insult. Perturbation of the quantity or function of regulatory T cells (Tregs) in BA could result in unchecked autoimmunity. The aim of this study is to determine if Tregs are diminished or dysfunctional in murine and human BA. Murine BA results from infection of BALB/c neonates with Rhesus rotavirus (RRV). Mice infected with RRV on day 1 that received either Tregs or control T cells on day 5 led to a difference in disease status as early as 4 days post-transfer. This trend continued and biliary disease occurred in 67% of controls vs. 39% of Tregs recipients at 17 days of life. Secondly, ablation of functional Tregs in 4 day-old mice by treatment with a CD25-depleting antibody followed by RRV infection 3 days later results in increased bile duct infiltrate and disease incidence at 3 weeks of age. Finally, analysis of human PBMCs revealed a decreased percentage of FoxP3+ Tregs in BA patients (1.5±0.3%) compared to age-matched controls (4.1±0.7%). These studies suggest that lack of or dysregulation of Tregs is present in the murine model of BA and that diminished numbers of Tregs may be implicated in human BA progression.
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Probert, C. S., A. D. Christ, L. J. Saubermann, J. R. Turner, A. Chott, D. Carr-Locke, S. P. Balk, and R. S. Blumberg. "Analysis of human common bile duct-associated T cells: evidence for oligoclonality, T cell clonal persistence, and epithelial cell recognition." Journal of Immunology 158, no. 4 (February 15, 1997): 1941–48. http://dx.doi.org/10.4049/jimmunol.158.4.1941.

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Abstract The phenotype of T cells associated with the common bile duct (CBD) is unknown. We investigated the hypothesis that they behave like other intraepithelial lymphocytes (IEL). Thus, we sought to determine the phenotype, TCR repertoire, and epithelial recognition of T cells obtained during endoscopic retrograde cholangiopancreatography. Three subjects were studied: two with primary sclerosing cholangitis and one normal control. After establishing a short-term T cell line, cells were 1) stained with mAbs for flow cytometric analysis, 2) analyzed for TCRB chain transcript expression, and 3) used as effector cells for cytotoxicity and proliferation. Flow cytometry revealed that for all the subjects 98% of the T cells were TCR-alpha beta-positive. Immunohistology of the CBD showed that the epithelium and lamina propria contained significant numbers of CD3+ CD43+ CD45RO+ lymphocytes. Complementarity-determining region 3 length displays suggested that the CBD-derived lines were oligoclonal. This was confirmed by cloning and random sequencing of PCR amplification products using TCRBV region family-specific primers; TCRB chain sequences were reiterated in all transcripts analyzed. In one case, two expanded TCRB clones could be identified that were persistent in the bile duct over a 1-yr period. The CBD-derived lines were cytolytic in a redirected lysis assay and caused cytolysis of an intestinal epithelial cell line (Caco-2). This recognition was likely preferential for intestinal epithelial cells, since a CBD-derived line exhibited proliferation to two intestinal epithelial cell lines (HT-29 and Caco-2) but not three other lines (HepG2, human foreskin fibroblast, and KD). We conclude that the CBD contains IELs that share several characteristics with intestinal IELs.
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Uchida, Kazushige, Takeo Kusuda, Masanori Koyabu, Hideaki Miyoshi, Norimasa Fukata, Kimi Sumimoto, Yuri Fukui, et al. "Regulatory T Cells in Type 1 Autoimmune Pancreatitis." International Journal of Rheumatology 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/795026.

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Autoimmune pancreatitis (AIP) is a newly recognized pancreatic disorder. Recently, International Consensus Diagnostic Criteria for AIP (ICDC) was published. In this ICDC, AIP was classified into Type 1 and Type 2. Patients with Type 1 AIP have several immunologic and histologic abnormalities specific to the disease, including increased levels of serum IgG4 and storiform fibrosis with infiltration of lymphocytes and IgG4-positive plasmacytes in the involved organs. Among the involved organs showing extrapancreatic lesions, the bile duct is the most common, exhibiting sclerosing cholangitis (IgG4-SC). However, the role of IgG4 is unclear. Recently, it has been reported that regulatory T cells (Tregs) are involved in both the development of various autoimmune diseases and the shift of B cells toward IgG4, producing plasmacytes. Our study showed that Tregs were increased in the pancreas with Type 1 AIP and IgG4-SC compared with control. In the patients with Type 1 AIP and IgG4-SC, the numbers of infiltrated Tregs were significantly positively correlated with IgG4-positive plasma cells. In Type 1 AIP, inducible costimulatory molecule (ICOS)+and IL-10+Tregs significantly increased compared with control groups. Our data suggest that increased quantities of ICOS+Tregs may influence IgG4 production via IL-10 in Type 1 AIP.
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Jones, David E. J. "T-Cell Autoimmunity in Primary Biliary Cirrhosis." Clinical Science 91, no. 5 (November 1, 1996): 551–58. http://dx.doi.org/10.1042/cs0910551.

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1. Primary biliary cirrhosis is a chronic cholestatic liver disease with an autoimmune aetiology. The classical histopathological lesion, of portal tract biliary epithelial cell damage, is accompanied by a T-cell-rich mononuclear cell infiltrate and upregulation of cell surface markers suggestive of local T-cell activation and cytokine release. This suggests that T-cell mediated mechanisms play an important role in tissue damage in primary biliary cirrhosis. 2. CD4+ T-cells specific for the E2 component of human pyruvate dehydrogenase complex (PDC-E2), a highly conserved enzyme which plays a critical role in intermediate metabolism, are present in the peripheral repertoire of the majority of patients with primary biliary cirrhosis. These cells are almost entirely absent from normal and chronic liver disease control subjects. The observations that peripheral blood PDC-E2-specific cells are most commonly seen in early stage disease, when active bile duct damage is occurring, and that PDC-E2-specific cells can be found in the portal tract infiltrate at times when this damage is occurring, suggest that these autoreactive cells may have a role to play in the aetiology of primary biliary cirrhosis. 3. T-cells specific for the whole PDC and its E1 component are seen in significant numbers of normal control subjects as well as patients with primary biliary cirrhosis. Retention of potentially autoreactive cells in the normal T-cell repertoire has been reported for a number of other autoantigens. 4. T-cell epitopes appear to be widely distributed throughout PDC-E2. This is in contrast to the B-cell epitopes which are highly restricted to the inner lipoyl binding domain of the protein.
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Fujihashi, K., J. R. McGhee, M. N. Kweon, M. D. Cooper, S. Tonegawa, I. Takahashi, T. Hiroi, J. Mestecky, and H. Kiyono. "gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses." Journal of Experimental Medicine 183, no. 4 (April 1, 1996): 1929–35. http://dx.doi.org/10.1084/jem.183.4.1929.

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Mucosal tissues of mice are enriched in T cells that express the gamma/delta T cell receptor. Since the function of these cells remains unclear, we have compared mucosal immune responses in gamma/delta T cell receptor-deficient (TCRdelta-/-) mice versus control mice of the same genetic background. The frequency of intestinal immunoglobulin (Ig) A plasma cells as well as IgA levels in serum, bile, saliva, and fecal samples were markedly reduced in TCRdelta-/- mice. The TCRdelta-/- mice produced much lower levels of IgA antibodies when immunized orally with a vaccine of tetanus toxoid plus cholera toxin as adjuvant. Conversely, the antigen-specific IgM and IgG antibody responses were comparable to orally immunized control mice. Direct assessment of the cells forming antibodies against the tetanus toxoid and cholera toxin antigens indicated that significantly lower numbers of IgA antibody-producing cells were present in the intestinal lamina propria and Peyer's patches of TCRdelta-/- mice compared with the orally immunized control mice. The selective reduction of IgA responses to ingested antigens in the absence of gamma/delta T cells suggests a specialized role for gamma/delta cells in mucosal immunity.
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Huang, Shing-Moo, Chung-Chin Yao, Ya-Wen Cheng, Ling-Yun Chen, Huichin Pan, Kuang-Ming Hsiao, Mei-Due Yang, Chew-Wun Wu, Wing-Yiu Lui, and Te-Jen Lai. "Laparoscopic Primary Closure of Common Bile Duct Combined with Percutaneous Cholangiographic Drainage for Treating Choledocholithiasis." American Surgeon 76, no. 5 (May 2010): 517–21. http://dx.doi.org/10.1177/000313481007600521.

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The aim of this study was to compare the efficacy and safety of laparoscopic primary closure of the common bile duct (CBD) combined with percutaneous transhepatic cholangiographic drainage (PTCD) and laparoscopic choledocholithotomy with T-tube placement for the treatment of CBD stones. Between January 1991 and July 2002, 50 patients with choledocholithiasis and a CBD diameter larger than or equal to 1 cm underwent laparoscopic CBD explorations. The study group consisted of 10 patients undergoing laparoscopic primary closure of the CBD combined with PTCD. The control group consisted of 40 patients undergoing laparoscopic choledocholithotomy with T-tube placement. Parameters were compared statistically. The study group showed higher female/male ratio (6/4 vs 8/32, P = 0.02), less stone numbers (1.90 ± 0.88 vs 3.40 ± 1.65, P = 0.0078), shorter operation time (138 ± 37 minutes vs 191 ± 75 minutes, P = 0.014), and shorter postoperative stays (7 ± 3 days vs 10 ± 3 days, P = 0.0013). It seems that laparoscopic primary closure of the CBD combined with PTCD can shorten the operation time and postoperative stays as compared with laparoscopic choledocholithotomy with T-tube placement for the treatment of CBD stones.
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Hofmann, Tanja, Sonja Schmucker, Vera Sommerfeld, Korinna Huber, Markus Rodehutscord, and Volker Stefanski. "Immunomodulatory Effects of Dietary Phosphorus and Calcium in Two Strains of Laying Hens." Animals 11, no. 1 (January 8, 2021): 129. http://dx.doi.org/10.3390/ani11010129.

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Insufficient nutrient supply can impair the immune system, which is important for animal health and welfare. Since chicken can partly hydrolyze phytate, which is the primary phosphorus storage in plant seeds, a reduction of mineral phosphorus in the diets could be an option for more sustainable egg production. Laying hens require high concentrations of calcium that might inhibit the function of endogenous enzymes for phytate hydrolyzation. The objective of this study was to characterize the impact of standard and reduced dietary phosphorus and calcium concentrations on the number and functionality of immune cells in the peripheral and gut-associated immune system in a white and brown laying hen strain. Reduced mineral phosphorus enhanced several immune parameters such as B cells in blood and IgA concentrations in bile in both strains, and peripheral monocytes and T cells in cecal tonsils in brown hens. Reduced calcium levels resulted in lower numbers of T cells in blood and cecal tonsils in both strains, suggesting negative effects on adaptive immunity. Differences between the two strains were found in almost all immune parameters. Results suggest a potentially beneficial effect of reduced dietary mineral phosphorus on the immune system that is dependent on the genetic background.
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Hofmann, Tanja, Sonja Schmucker, Vera Sommerfeld, Korinna Huber, Markus Rodehutscord, and Volker Stefanski. "Immunomodulatory Effects of Dietary Phosphorus and Calcium in Two Strains of Laying Hens." Animals 11, no. 1 (January 8, 2021): 129. http://dx.doi.org/10.3390/ani11010129.

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Insufficient nutrient supply can impair the immune system, which is important for animal health and welfare. Since chicken can partly hydrolyze phytate, which is the primary phosphorus storage in plant seeds, a reduction of mineral phosphorus in the diets could be an option for more sustainable egg production. Laying hens require high concentrations of calcium that might inhibit the function of endogenous enzymes for phytate hydrolyzation. The objective of this study was to characterize the impact of standard and reduced dietary phosphorus and calcium concentrations on the number and functionality of immune cells in the peripheral and gut-associated immune system in a white and brown laying hen strain. Reduced mineral phosphorus enhanced several immune parameters such as B cells in blood and IgA concentrations in bile in both strains, and peripheral monocytes and T cells in cecal tonsils in brown hens. Reduced calcium levels resulted in lower numbers of T cells in blood and cecal tonsils in both strains, suggesting negative effects on adaptive immunity. Differences between the two strains were found in almost all immune parameters. Results suggest a potentially beneficial effect of reduced dietary mineral phosphorus on the immune system that is dependent on the genetic background.
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Dissertations / Theses on the topic "Bible. O.T. Numbers"

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Ferrarini, Marco. "Evaluation of CD8+ T-cell numbers and repertoires." Thesis, University of Leeds, 2018. http://etheses.whiterose.ac.uk/21520/.

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This thesis tackles the problem of T-cell receptor (TCR) diversity, from two different points of view. On one hand, the observed TCR diversity is studied from a mathematical perspective, concentrating on the probability of a sample to reproduce a certain percentage of the total TCR diversity. On the other hand, biological samples are considered, focusing on statistical analysis of the observed VDJ gene segments. To conclude, a stochastic model is developed to explore the population dynamics of a simulated TCR repertoire. Computer simulations complete this multidisciplinary approach, helping verifying the different mathematical theories behind the stochastic models.
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Van, Gorp Terry L. "An investigation of serpent symbolism and Numbers 21:4-9." Theological Research Exchange Network (TREN), 1986. http://www.tren.com.

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Ingram, Douglas Nairn. "The ambiguity of Qohelet : a study of the ambiguous nature of the language, syntax and structure of the Masoretic text of Qohelet." Thesis, University of Stirling, 1996. http://hdl.handle.net/1893/2589.

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The premise upon which this thesis is founded is that the book of Qohelet is fundamentally ambiguous. Ambiguity is attached to all its major themes, and can be discerned in its language, syntax and structure. This has not been given due attention in previous works on Qohelet. The introduction considers the concepts of 'ambiguity' and 'meaning': it is crucial for the reader to understand what is meant in this thesis by these terms. 'Ambiguity' is understood as those aspects of the text whose indeterminacy requires the reader to fill in 'meaning' in order for a coherent reading to be produced: thus the reader's role is crucial, but is nonetheless restricted by the determinate schemata in the text. Part 1 explores the determinate schemata in Qohelet in an attempt to provide objective criteria against which the ambiguities may be set. Detailed attention is paid to the text in order to discern trends and patterns in the book. These are employed in an attempt to discover how the book as a whole and the sections within it are structured. Part 1 ends by asserting that it is ultimately futile to seek an overall structure or pattern to the book: this is an aspect of its ambiguity. Part 2 systematically examines linguistic and syntactical ambiguities in Qohelet, exploring the possibilities for interpretation according to the ways in which the reader fills in the gaps left by these ambiguities. The conclusion argues that the ambiguity of Qohelet is the primary reason for the hugely diverse interpretations of the book throughout its history, and for the many varied proposals for its structure. In this way it is a realistic reflection of an ambiguous world and the relationship between the people of this world and the God who made the world with all its ambiguities.
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Shumate, David R. "The vindication of God's leadership the divine probation of the theocratic order in Numbers 10:11-25:18 and its contribution to the structure and message of the book as a whole /." Online full text .pdf document, available to Fuller patrons only, 2001. http://www.tren.com.

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Giere, Samuel D. "A new glimpse of Day One : an intertextual history of Genesis 1.1-5 in Hebrew and Greek texts up to 200 CE." Thesis, University of St Andrews, 2007. http://hdl.handle.net/10023/155.

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This thesis is an unconventional history of the interpretation of Day One, Genesis 1.1-5, in Hebrew and Greek texts up to c. 200 CE. Using the concept of ‘intertextuality’ as developed by Kristeva, Derrida, and others, the method for this historical exploration looks at the dynamic interconnectedness of texts. The results reach beyond deliberate exegetical and eisegetical interpretations of Day One to include intertextual, and therefore not necessarily deliberate, connections between texts. The purpose of the study is to gain a glimpse into the textual possibilities available to the ancient reader / interpreter. Central to the method employed is the identification of the intertexts of Day One. This is achieved, at least in part, by identifying and tracing flags that may draw the reader from one text to another. In this study these flags are called ‘intertextual markers’ and may be individual words, word-pairs, or small phrases that occur relatively infrequently within the corpus of texts being examined. The thesis first explores the intertextuality of Genesis 1.1-5 in the confines of the Hebrew Bible and the Septuagint. The second half of the thesis identifies and explores the intertexts of Day One in other Hebrew texts (e.g. the Dead Sea Scrolls, Sirach) and other Greek texts (e.g. Philo, the New Testament) up to c. 200 CE. The thesis concludes with a summation of some of the more prominent and surprising threads in this intertextual ‘tapestry’ of Day One. These summary threads include observations within the texts in a given language and a comparative look at the role of language in the intertextual history of Day One.
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Uhlenbruch, Frauke. "The Nowhere Bible : the Biblical passage Numbers 13 as a case study of Utopian and Dystopian readings by diachronic audiences." Thesis, University of Derby, 2014. http://hdl.handle.net/10545/315827.

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Applying utopian theory to the Bible reveals a number of issues surrounding the biblical text within academic disciplines such as biblical studies, which study the Bible as an ancient cultural artefact, and among religious readers of the Bible. The biblical passage Numbers 13 was chosen as a case study of a utopian reading of the image of the Promised Land to demonstrate the Bible’s multifaceted potential by externalising the presupposition brought to the text. The underlying method is derived from an ideal type procedure, appropriated from Weber. Instead of comparing phenomena to each other, one compares a phenomenon to a constructed ideal type. This method enables one to compare phenomena independently of exclusive definitions and direct linear influences. It has been suggested by biblical scholars that utopian readings of the Bible can yield insights into socio-political circumstances in the society which produced biblical texts. Using observations by Holquist about utopias’ relationships to reality it is asked if applying the concept of utopia to a biblical passage allows drawing conclusions about the originating society of the Hebrew Bible. The answer is negative. Theory about literary utopias is applied to the case study passage. Numbers 13 is similar to literary utopias in juxtaposing a significantly improved society with a home society, the motif of travellers in an unfamiliar environment, and the feature of a map which is graphically not representable. Noth’s reading of the biblical passage’s toponyms reveals that its map is a utopian map. Numbers 13 is best understood as a literary utopia describing an unrealistic environment and using common utopian techniques and motifs. Despite describing an unrealistic environment, the passage was understood as directly relevant to reality by readers throughout time, for example by Bradford. Following two Puritan readings, it is observed that biblical utopian texts have the potential of being applied in reality by those who see them as a call to action. If a literary utopia is attempted to be brought into reality, it becomes apparent that it marginalises those who are not utopian protagonists; in the case study passage, the non-Israelite tribes, in Bradford’s reading, the Native Nations in New England. The interplay of utopia and dystopia is explored and it is concluded that a definitive trait of literary utopias is their potential to turn into an experienced dystopia if enforced literally. This argument is supported by demonstrating that the utopian traits of the case study passage contain dystopian downsides if read from a different perspective. A contemporary utopian reading of the case study passage is proposed. Today utopian speculation most often appears in works of science fiction (SF). Motifs appearing in the case study passage are read as tropes familiar to a contemporary Bible reader from SF. Following D. Suvin’s SF theory, it is concluded that the Bible in the contemporary world can be understood as a piece of SF. It contains the juxtaposition of an estranged world with a reader’s experienced world as well as a potential utopian and dystopian message.
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Mangililo, Ira. "Rahab speaks back : a postcolonial feminist analysis of Joshua 2:1-24." Thesis, University of Wales Trinity Saint David, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.683063.

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Saxon, David L. "Fundamentalist Bibliology 1870-1900 an analysis of the early fundamentalist views of inspiration, Bible translations, and Bible criticism from the writings of James H. Brookes, A.J. Gordon, and A.T. Pierson /." Theological Research Exchange Network (TREN), 1998. http://www.tren.com.

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Oualha, Khaled. "Étude expérimentale et numérique de l'hydrodynamique de l’écoulement dans un réacteur continu." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCD082/document.

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Au cours de ce travail de thèse, sur l'hydrodynamique de l'écoulement dans le un réacteur continu, où les propriétés des nanomatériaux élaborés dépendent des caractéristiques morphologiques et structurales de la solution colloïdale issue du réacteur, nous avons d'abord optimisé les conditions d'utilisation (Re ≈ 6000), ainsi que la géométrie du T-mélange dans le but d'améliorer la qualité du micro-mélange. Ensuite, des mesures expérimentales ont permis de vérifier que la condition de Damköhler est respectée (Da ≤ 1). Enfin, ce résultat a été validé numériquement. Au delà de cette valeur de Re critique (Re* ≈ 8000), nous avons mis en évidence le phénomène de cavitation dans le T-mélange. Ce phénomène à été étudié expérimentalement, par des mesures SLS, et numériquement par des simulations CFD. Les résultats obtenus par ces deux approches concordent. Enfin, des mesures DLS ont été effectuées pour étudier et caractériser les bulles de cavitation. Ces dernières ont permis d'évaluer la taille des bulles ainsi que leur trajectoire le long de l'axe Z à la sortie du T-mélange. Cette étude a été suivie par des simulations numériques de la cavitation et du modèle multiphasique dans notre écoulement. Les deux études, expérimentale et numérique, ont confirmé que la diminution de l'intensité de la lumière diffusée mesurée par SLS le long de l'axe Z est due à l'évolution du nombre et de la taille des bulles
During this Phd work, on the hydrodynamics of flow in a continuous reactor, where the properties of the elaborated nanomaterials depend on the morphological and structural characteristics of the colloidal solution out coming from the reactor, we first optimized the conditions of use of the latter (Re ≈ 6000), as well as the geometry of the T-mixer in order to improve the quality of the micro-mixing. Then, experimental measurements allowed us to verify that the condition of Damköhler is respected (Da ≤ 1). Finally, this result has been validated numerically. Beyond this Re critical value (Re * ≈ 8000), we have highlighted the phenomenon of cavitations in the T-mixer. This phenomenon has been studied experimentally, by SLS measurements, and numerically by CFD simulation. The results obtained by these two approaches are in agreement. Finally, DLS measurements were made to study and characterize cavitations bubbles. These measurements allowed us to evaluate the size of the bubbles as well as their trajectory along the Z axis 121 at the outlet of the T-mixer. This study was followed by numerical simulations of the cavitations and the multiphase model in our flow. Both experimental and numerical studies confirmed that the decrease in the intensity of scattered light measured by SLS along the Z axis is result to the changes of the number and the size of bubbles
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Hiejima, Eitaro. "Reduced numbers and proapoptotic features of mucosal-associated invariant T cells as a characteristic finding in IBD patients." Kyoto University, 2016. http://hdl.handle.net/2433/204557.

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Books on the topic "Bible. O.T. Numbers"

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Numbers. Grand Rapids, MI: Brazos, 2009.

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Cole, R. Dennis. Numbers. Nashville, Tenn: Broadman & Holman, 2000.

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Numbers: The law numbers. [Place of publication not identified]: Thomas Nelson, 1995.

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1947-, Anders Max E., ed. Exodus, Leviticus, Numbers. Nashville, Tenn: Broadman & Holman, 2002.

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Leviticus and Numbers. Peabody, Mass: Hendrickson Publishers, 2001.

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The book of Numbers. Grand Rapids, Mich: William B. Eerdmans, 1993.

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The book of Numbers. Grand Rapids, Mich: Eerdmans, 1993.

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Numbers: A practical commentary. Grand Rapids, Mich: Eerdmans, 1987.

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Leviticus and Numbers. Minneapolis, Min: Fortress Press, 2013.

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The book of Numbers: A critique of Genesis. New Haven: Yale University Press, 2012.

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Book chapters on the topic "Bible. O.T. Numbers"

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Brimhall, Jason, David Dye, Jonathan Gennick, Andy Roberts, and Wayne Sheffield. "Working with Numbers." In SQL Server 2012 T-SQL Recipes, 219–40. Berkeley, CA: Apress, 2012. http://dx.doi.org/10.1007/978-1-4302-4201-7_11.

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Brimhall, Jason, Jonathan Gennick, and Wayne Sheffield. "Chapter 11: Working with Numbers." In SQL Server T-SQL Recipes, 255–78. Berkeley, CA: Apress, 2015. http://dx.doi.org/10.1007/978-1-4842-0061-2_11.

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Robbins, Neville, and M. V. Subbarao. "Some Parity Results Regarding t-Core Partitions." In Applications of Fibonacci Numbers, 201–11. Dordrecht: Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-0-306-48517-6_20.

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Davidson, Graham. "S. T. Coleridge." In The Blackwell Companion to the Bible in English Literature, 413–24. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444324174.ch29.

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Fuller, David. "T. S. Eliot." In The Blackwell Companion to the Bible in English Literature, 667–80. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444324174.ch48.

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Caveny, Deanna. "U-Numbers and T-Numbers: Some Elementary Transcendence and Algebraic Independence Results." In Number Theory with an Emphasis on the Markoff Spectrum, 43–52. Taylor & Francis Group, 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742: CRC Press, 2017. http://dx.doi.org/10.4324/9780203747018-7.

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Bey, Christian, and Konrad Engel. "Old and New Results for the Weighted t-Intersection Problem via AK-Methods." In Numbers, Information and Complexity, 45–74. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/978-1-4757-6048-4_5.

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Marzo, Amanda L., Ryan T. Sowell, and Bernadette Scott. "The Role of Precursor Frequency in the Differentiation of Memory T Cells: Memory by Numbers." In Memory T Cells, 69–78. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6451-9_6.

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Bassalygo, Leonid, and Mark Pinsker. "Calculation of the Asymptotically Optimal Capacity of a T-User M-Frequency Noiseless Multiple-Access Channel." In Numbers, Information and Complexity, 177–80. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/978-1-4757-6048-4_16.

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Mackay, C. R., and W. R. Hein. "Marked Variations in γδT Cell Numbers and Distribution Throughout the Life of Sheep." In Function and Specificity of γ/δ T Cells, 107–11. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76492-9_15.

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Conference papers on the topic "Bible. O.T. Numbers"

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Verleysen, Cédric, and Christophe De Vleeschouwer. "Recognition of sport players' numbers using fast-color segmentation." In IS&T/SPIE Electronic Imaging, edited by Amir Said, Onur G. Guleryuz, and Robert L. Stevenson. SPIE, 2012. http://dx.doi.org/10.1117/12.908723.

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Zhang, Xujie, Tamar Kashti, Dror Kella, Tal Frank, Doron Shaked, Robert Ulichney, Mani Fischer, and Jan P. Allebach. "Measuring the modulation transfer function of image capture devices: what do the numbers really mean?" In IS&T/SPIE Electronic Imaging, edited by Frans Gaykema and Peter D. Burns. SPIE, 2012. http://dx.doi.org/10.1117/12.912989.

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Liu, Pei-De, and Shyi-Ming Chen. "Heronian aggregation operators of intuitionistic fuzzy numbers based on the Archimedean t-norm and t-conorm." In 2016 International Conference on Machine Learning and Cybernetics (ICMLC). IEEE, 2016. http://dx.doi.org/10.1109/icmlc.2016.7872971.

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Krasnobayev, Victor, Alexandr Kuznetsov, Mykhaylo Bagmut, and Yelyzaveta Kuznetsova. "Design of the Residual Adder of Two Numbers." In 2021 IEEE 8th International Conference on Problems of Infocommunications, Science and Technology (PIC S&T). IEEE, 2021. http://dx.doi.org/10.1109/picst54195.2021.9772132.

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Chiao, Kuo-Ping. "Controllable Fuzziness of General Fuzzy Numbers Addition Based on Yager T-norms." In 2019 IEEE International Conference on Fuzzy Systems (FUZZ-IEEE). IEEE, 2019. http://dx.doi.org/10.1109/fuzz-ieee.2019.8858831.

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Zheng, Jiaying. "PD-1 Inhibitor Treatment in Mastocytosis Increasing T and NK Cell Numbers and Activation." In ISAIMS 2022: 2022 3rd International Symposium on Artificial Intelligence for Medicine Sciences. New York, NY, USA: ACM, 2022. http://dx.doi.org/10.1145/3570773.3570884.

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Klapa, Sebastian, Anja Kerstein, Andreas Koch, Silke Pitann, Relana Nieberding, Gabriela Riemekasten, Antje Müller, and Peter Lamprecht. "SAT0021 ELEVATED NUMBERS OF C-TYPE LECTIN CD161 POSITIVE PR3-SPECIFIC T-CELLS IN GPA." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.6771.

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Samoshchenko, Oleksandr, Irina Zeleneva, Heorhii Marhiiev, and Oleksandr Miroshkin. "Biased Exponents Encoding With Positive Zero When Comparing Absolute Values of Floating-Point Numbers." In 2020 IEEE International Conference on Problems of Infocommunications. Science and Technology (PIC S&T). IEEE, 2020. http://dx.doi.org/10.1109/picst51311.2020.9468077.

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Fu, X., J. Li, X. Li, J. Luo, C. Gao, and Q. Chen. "OP0132 Low-dose INTERLEUKIN-2 selectively restore regulatory T cell numbers in patients with behcet's disease." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.4047.

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Kockmann, Norbert, Simon Dreher, and Peter Woias. "Unsteady Laminar Flow Regimes and Mixing in T-Shaped Micromixers." In ASME 2007 5th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2007. http://dx.doi.org/10.1115/icnmm2007-30041.

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Convective micromixers create vortices in curved channel elements and allow characteristic mixing times below 1 millisecond for gaseous and liquid media. The flow regimes in the T-shaped junction of rectangular microchannels determine the mixing characteristics of the device. This contribution gives an overview about the flow regimes of symmetrical 1:1 mixing in T-shaped micromixers for Reynolds numbers from 0.01 to 1000 in the mixing channel. CFD simulations with the CFD-ACE+ code of ESI group give a detailed picture of the flow and mixing regimes in the investigated range of Reynolds numbers Re. First symmetrical vortices are formed at the entrance of the mixing channel for Re > 10. Due the symmetrical flow and the undisturbed interface between the components, the mixing quality at a distinct mixing channel length decreases with increasing Re number. At a certain Re number of about 140, the flow symmetry is disturbed, fluid from one side swaps to the opposite side and creates a double vortex within the mixing channel. For Re > 240 the flow becomes unsteady. The vortex formation at the mixing channel entrance is disturbed and a kind of wake flow establishes within the mixing channel. From 240 < Re < 500 the wake flow is periodic with a dimensionless frequency, the Strouhal number Sr of about 0.2. The Sr number is found to be the same in scaled mixer geometries. The mixing quality shows also a periodic behavior and reaches its maximum at this point. With further increasing Re number, the flow starts to become chaotic and the two components are often flowing parallel in the mixing channel leading to a decreasing mixing quality. Besides detailed CFD simulations, the periodic flow is observed in experimental studies with colored flow and stroboscopic imaging and has the same frequency. The decreasing mixing quality is also reflected in a lower selectivity of parallel, chemical test reactions for Re numbers larger than 500. With the knowledge of the flow regimes in microchannels, design criteria can be formulated for efficient mixing devices.
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Reports on the topic "Bible. O.T. Numbers"

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Harman, Gary E., and Ilan Chet. Enhancement of plant disease resistance and productivity through use of root symbiotic fungi. United States Department of Agriculture, July 2008. http://dx.doi.org/10.32747/2008.7695588.bard.

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The objectives of the project were to (a) compare effects ofT22 and T-203 on growth promotion and induced resistance of maize inbred line Mol7; (b) follow induced resistance of pathogenesis-related proteins through changes in gene expression with a root and foliar pathogen in the presence or absence of T22 or T-203 and (c) to follow changes in the proteome of Mol? over time in roots and leaves in the presence or absence of T22 or T-203. The research built changes in our concepts regarding the effects of Trichoderma on plants; we hypothesized that there would be major changes in the physiology of plants and these would be reflected in changes in the plant proteome as a consequence of root infection by Trichoderma spp. Further, Trichoderma spp. differ in their effects on plants and these changes are largely a consequence of the production of different elicitors of elicitor mixtures that are produced in the zone of communication that is established by root infection by Trichoderma spp. In this work, we demonstrated that both T22 and T-203 increase growth and induce resistance to pathogens in maize. In Israel, it was shown that a hydrophobin is critical for root colonization by Trichoderma strains, and that peptaibols and an expansin-like protein from Ttrichoderma probably act as elicitors of induced resistance in plants. Further, this fungus induces the jasmonate/ethylene pathway of disease resistance and a specific cucumber MAPK is required for transduction of the resistance signal. This is the first such gene known to be induced by fungal systems. In the USA, extensive proteomic analyses of maize demonstrated a number of proteins are differentially regulated by T. harzianum strain T22. The pattern of up-regulation strongly supports the contention that this fungus induces increases in plant disease resistance, respiratory rates and photosynthesis. These are all very consistent with the observations of effects of the fungus on plants in the greenhouse and field. In addition, the chitinolytic complex of maize was examined. The numbers of maize genes encoding these enzymes was increased about 3-fold and their locations on maize chromosomes determined by sequence identification in specific BAC libraries on the web. One of the chitinolytic enzymes was determined to be a heterodimer between a specific exochitinase and different endochitinases dependent upon tissue differences (shoot or root) and the presence or absence of T. harzianum. These heterodimers, which were discovered in this work, are very strongly antifungal, especially the one from shoots in the presence of the biocontrol fungus. Finally, RNA was isolated from plants at Cornell and sent to Israel for transcriptome assessment using Affymetrix chips (the chips became available for maize at the end of the project). The data was sent back to Cornell for bioinformatic analyses and found, in large sense, to be consistent with the proteomic data. The final assessment of this data is just now possible since the full annotation of the sequences in the maize Affy chips is just now available. This work is already being used to discover more effective strains of Trichoderma. It also is expected to elucidate how we may be able to manipulate and breed plants for greater disease resistance, enhanced growth and yield and similar goals. This will be possible since the changes in gene and protein expression that lead to better plant performance can be elucidated by following changes induced by Trichoderma strains. The work was in, some parts, collaborative but in others, most specifically transcriptome analyses, fully synergistic.
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Ullman, Diane, James Moyer, Benjamin Raccah, Abed Gera, Meir Klein, and Jacob Cohen. Tospoviruses Infecting Bulb Crops: Evolution, Diversity, Vector Specificity and Control. United States Department of Agriculture, September 2002. http://dx.doi.org/10.32747/2002.7695847.bard.

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Objectives. The overall goal of the proposed research was to develop a mechanistic understanding of tospovirus evolution, diversity and vector specificity that could be applied to development of novel methods for limiting virus establishment and spread. Our specific objectives were: 1) To characterize newly intercepted tospoviruses in onion, Hippeastrum and other bulb crops and compare them with the known tomato spotted wilt virus (TSWV) and its isolates; 2) To characterize intra- and interspecific variation in the virus transmission by thrips of the new and distinct tospoviruses. and, 3) To determine the basis of vector specificity using biological, cellular and molecular approaches. Background. New tospoviruses infecting bulb crops were detected in Israel and the US in the mid-90s. Their plant host ranges and relationships with thrips vectors showed they differed from the type member of the Tospovirus genus, tomato spotted wilt virus (TSWV). Outbreaks of these new viruses caused serious crop losses in both countries, and in agricultural and ornamental crops elsewhere. In the realm of plant infecting viruses, the tospoviruses (genus: Tospovirus , family: Bunyaviridae ) are among the most aggressive emerging viruses. Tospoviruses are transmitted by several species of thrips in a persistent, propagative fashion and the relationships between the viruses and their thrips vectors are often specific. With the emergence of new tospoviruses, new thrips vector/tospovirus relationships have also arisen and vector specificities have changed. There is known specificity between thrips vector species and particular tospoviruses, although the cellular and molecular bases for this specificity have been elusive. Major conclusions, solutions and achievements. We demonstrated that a new tospovirus, iris yellow spot virus (IYSV) caused "straw bleaching" in onion (Allium cepa) and lisianthus necrosis in lisianthus (Eustoma russellianum). Characterization of virus isolates revealed genetic diversity among US, Brazilian, Dutch and Israeli isolates. IYSV was not seed transmitted, and in Israel, was not located in bulbs of infected plants. In the US, infected plants were generated from infected bulbs. The relationship between IYSV and Thrips tabaci was shown to be specific. Frankliniella occidentalis, the primary vector of many other tospoviruses, did not transmit IYSV isolates in Israel or the US. Furthermore, 1': tabaci populations varied in their transmission ability. Transmission was correlated to IYSV presence in thrips salivary glands. In Israel, surveys in onion fields revealed that the onion thrips, Thrips tabaci Lindeman was the predominant species and that its incidence was strongly related to that of IYSV infection. In contrast, in the U.S., T. tabaci and F. occidentalis were present in high numbers during the times sampled. In Israel, insecticides reduced onion thrips population and caused a significant yield increase. In the US, a genetic marker system that differentiates non-thrips transmissible isolates from thrips transmissible isolate demonstrated the importance of the M RNA to thrips transmission of tospoviruses. In addition, a symbiotic Erwinia was discovered in thrips and was shown to cause significant artifacts in certain types of virus binding experiments. Implications, scientific and agricultural. Rapid emergence of distinct tospoviruses and new vector relationships is profoundly important to global agriculture. We advanced the understanding of IYSV in bulb crops and its relationships with thrips vector species. The knowledge gained provided growers with new strategies for control and new tools for studying the importance of particular viral proteins in thrips specificity and transmission efficiency.
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