Academic literature on the topic 'Bicyclic compound'

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Journal articles on the topic "Bicyclic compound"

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Pushpanathan, V., and D. Suresh Kumar. "Synthesis and Characterization of Zn Nanoparticles by Using Hetero-Bicyclic Compound." Advanced Materials Research 938 (June 2014): 3–8. http://dx.doi.org/10.4028/www.scientific.net/amr.938.3.

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The 1:1 condensation reaction between benzil and tris (hydroxymethyl) aminomethane in methanol yields a hetero bicyclic compound 5-(hydroxymethyl)-1,2-diphenyl-3,7-dioxa-8-aza-bicyclo [3.2.octan-2-ol. It was characterized by FT-IR, NMR (1H and 13C) spectroscopy and ESI mass spectrometry. The structure was conclusively determined by X-ray diffractrometric analysis. The structure shows a hetero bicyclic ring system. It consists of six membered morpholine and five membered oxazolidine rings with free hydroxyl groups. This bicyclic compound was used as a reducing and stabilizing agent to prepare z
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Corfield, Peter W. R., and Richard A. Kershaw. "Crystal structures of two bicyclo[5.1.0]octanes: potassiumtrans-bicyclo[5.1.0]octane-4-carboxylate monohydrate andcis-bicyclo[5.1.0]octan-4-yl 4-bromobenzenesulfonate." Acta Crystallographica Section E Crystallographic Communications 73, no. 9 (2017): 1357–62. http://dx.doi.org/10.1107/s2056989017011756.

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The crystal structures of thetrans-fused compound potassiumtrans-bicyclo[5.1.0]octane-4-carboxylate monohydrate, K+·C9H13O2−·H2O, (I), and ofcis-bicyclo[5.1.0]octan-4-yl 4-bromobenzenesulfonate, C14H17BrO3S, (II), have been determined. Compound (I) represents the smallesttrans-fused cyclopropane structure known to date, and features the expectedshorteningof the bridging C—C bond relative to the other cyclopropane bond lengths, in contrast to thecis-fused system, (II), where all of the cyclopropane bond lengths are the same. The bicyclic ring system of (I) is disordered across a crystallographi
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Lauro, Figueroa-Valverde, Rosas-Nexticapa Marcela, Lopez-Ramos Maria, et al. "Synthesis of a New Dioxaspiro[bicyclo[3.3.1]nonane-oxabicyclo[6.2.0]deca- 1(10),8-dien-4-one Derivative Using Some Chemical Strategies." Letters in Organic Chemistry 17, no. 5 (2020): 393–402. http://dx.doi.org/10.2174/1570178617666191116123359.

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There are several protocols for the preparation of bicyclic derivatives; however, some methods use dangerous and require special conditions. The aim of this study was to synthesize a new Dioxaspiro[ bicyclo[3.3.1]nonane-oxabicyclo[6.2.0]-deca-1(10), 8-dien-4-one (compound 8). Compound 8 was prepared using some reactions such as; i) etherification, ii) reduction, iii) amidation, iv) imination and v) 2+2 addition. The chemical structure of 8 and its intermediaries were completely characterized by spectroscopic techniques and elemental analysis. The synthesis showed a yield of 85% for compound 8.
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Suryanarayana Birudukota, N. V., Raimo Franke, and Bernd Hofer. "An approach to “escape from flatland”: chemo-enzymatic synthesis and biological profiling of a library of bridged bicyclic compounds." Organic & Biomolecular Chemistry 14, no. 15 (2016): 3821–37. http://dx.doi.org/10.1039/c5ob02539g.

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A small library of 78 bridged bicyclic compounds were synthesized via a chemo-enzymatic pathway. Biological evaluation suggested that rigid spherical scaffolds are useful to enhance the success rate of compound libraries for drug development.
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Ogoshi, Tomoki, Tomohiro Akutsu, and Tada-aki Yamagishi. "An amphiphilic pseudo[1]catenane: neutral guest-induced clouding point change." Beilstein Journal of Organic Chemistry 14 (July 26, 2018): 1937–43. http://dx.doi.org/10.3762/bjoc.14.167.

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The hydrophobic/hydrophilic ratio in a molecule largely affects its assembled properties in aqueous media. In this study, we synthesized a new bicyclic compound which could dynamically change its hydrophobic/hydrophilic ratio by chemical stimulus. The bicyclic compound consisted of amphiphilic pillar[5]arene and hydrophobic alkyl chain rings, and formed a self-inclusion structure in aqueous media, which was assigned as a pseudo[1]catenane structure. The hydrophobic chain ring was hidden inside the pillar[5]arene cavity in the pseudo[1]catenane structure, thus the bicyclic compound was soluble
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H., Möhrle, and Vetter W. "Oxidative Cyclisierungsreaktionen von 1-(3-Nitro-3-phenylpropyl)piperidin." Scientia Pharmaceutica 70, no. 2 (2002): 113–22. http://dx.doi.org/10.3797/scipharm.aut-02-13.

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The title compound 2 - prepared by Komblum reaction - reacted with Hg(II)-edta in a two electron withdrawal to a bicyclic compound 6, which showed in solution an equilibrium of two species probably of diastereomers, which was deduced from NMR-measurements. Additionally, resulting of an threefold dehydrogenation two diastereomeric bicyclic lactams 11A and 11B were isolated.
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Laus, Gerhard, Mirco E. Kostner, Volker Kahlenberg, and Herwig Schottenberger. "Synthesis and reactions of 2-azido-1,3-di(benzyloxy)imidazolium hexafluoridophosphate." Zeitschrift für Naturforschung B 71, no. 9 (2016): 997–1003. http://dx.doi.org/10.1515/znb-2016-0104.

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Abstract2-Azido-1,3-di(benzyloxy)imidazolium hexafluoridophosphate was obtained from the corresponding 2-bromo compound by reaction with sodium azide. Cycloaddition of the 2-azido compound with norbornene and norbornadiene gave the respective tricyclic aziridine and bicyclic azaoctadiene. Addition of triphenylphosphane yielded the phosphazide which upon heating eliminated dinitrogen to afford the phosphazene. The crystal structures of five compounds were determined by X-ray diffraction.
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Nie, Aihua, Sutapa Ghosh, and Ziwei Huang. "2′-[2-(4-Fluorophenyl)chroman-4-ylidene]isonicotinohydrazide." Acta Crystallographica Section E Structure Reports Online 62, no. 5 (2006): o1824—o1825. http://dx.doi.org/10.1107/s1600536806012153.

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In the title compound, C21H16FN3O2, the pyridine ring is nearly coplanar with the plane of the fused bicyclic ring system [dihedral angle = 4.1 (2)°], while the 4-fluorophenyl ring forms a dihedral angle of 67.7 (3)° with the fused bicyclic ring system.
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Christoffers, Jens, Wolfgang Frey, Heiko Scharl, and Angelika Baro. "Absolute Konfiguration von (+)-1,2,3,4,6,7,8,8a-Octahydro-6-isochinolon- 8a-carbonsäuremethylester und die Stereochemie einer Kupfer-katalysierten asymmetrischen Michael-Reaktion / Absolute Configuration of Methyl (+)-1,2,3,4,6,7,8,8a-Octahydro-6-isoquinolone-8a-carboxylate and Stereochemistry of a Copper-Catalyzed Asymmetric Michael Reaction." Zeitschrift für Naturforschung B 59, no. 4 (2004): 375–79. http://dx.doi.org/10.1515/znb-2004-0404.

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AbstractEnantiopure Boc-protected piperidine derivative (+)-5c, with a quaternary stereocenter, was obtained by copper-catalyzed, L-valine diethylamide-mediated Michael reaction. For determination of the absolute configuration, 5c was derivatized by cyclization with pyrrolidine/AcOH to give compound 6 with bicyclo[4.4.0]-constitution, deprotection of the amino function with TFA and subsequent reaction with 2-iodobenzoic acid to yield the crystalline bicyclic amide 7. X-ray crystallographic analysis confirmed the constitution of compounds 5c and 6 and established the (R) configuration of 7. Thu
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Guthrie, J. Peter, Roger T. Gallant, and Michael C. Jennings. "Preparation and characterization of bicyclic amide acetals and monothioacetals." Canadian Journal of Chemistry 82, no. 2 (2004): 268–78. http://dx.doi.org/10.1139/v03-204.

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We have prepared and characterized new examples of 5-substituted-1-aza-4,6-dioxabicyclo[3.3.0]octanes (bicyclic amide acetals) and examples of the new heterocyclic system, 5-substituted-1-aza-4-oxa-6-thiabicyclo[3.3.0]octanes (bicyclic amide monothioacetals). Detailed analysis of NMR coupling constants and X-ray structure determination for an example of each class of compound established the stereochemistry and conformation of these ring systems.Key words: bicyclic amide acetals, preparation, coupling constants, X-ray structure.
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Dissertations / Theses on the topic "Bicyclic compound"

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Becker, Christian. "Systèmes polymérisables à faible retrait et études de matériaux pour la stéréolithographie à laser CO2." Vandoeuvre-les-Nancy, INPL, 1994. http://docnum.univ-lorraine.fr/public/INPL_T_1994_BECKER_C.pdf.

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Cette thèse concerne l'étude des matériaux polymérisant avec de faibles variations de volume et dont les caractéristiques mécaniques sont compatibles avec les exigences d'applications pratiques telle que la stéréolithographie. Trois méthodes de réduction du retrait et leurs applications ont été étudiées: le premier système étudié comporte un monomère polyfonctionnel, un monomère difonctionnel possédant un point d'ébullition relativement bas et un polymère thermoplastique. Lors d'une polymérisation rapide, le système développe une exothermicité importante conduisant à une séparation de phase vi
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Er-Rhaimini, Abderrahman. "Hétérocycles azotes N-benziles : synthèse de dérivés N-benziles de l'adénine : étude de la photoélimination de substituants benzyliques." Angers, 1986. http://www.theses.fr/1986ANGE0002.

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Synthèse des cinq N-(dimethoxy-3,5 benzyl) adénines. Photolyse de ces compose en solution aqueuse. Tentative de synthèse de l'(imidazo (1,2-a) pyridinyl-6methyl)-1 adénine. Ce travail montre que des substituants benzyliques photoéliminables peuvent être utilisés comme groupes protecteurs dans des synthèses mettant en jeu l'adénine et ses dérivés.
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Barré, Virginie. "Synthèses de cétones à l'aide de propargyle sulfones." Paris 6, 1986. http://www.theses.fr/1986PA066495.

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On décrit une nouvelle méthode de cyclopentanation permettant, à partir d'une cyclopenténone, d'obtenir une bicyclo(3. 3. 0) octanédione, intermédiaire-cle de la synthèse d'une classe importante de composés naturels : les pentalenolactones. L'agent d'anhélation utilisé, une sulfone allylique comportant un reste alkylthio en position vinylique, est commodément préparé à partir d'une sulfone propargylique. Le synthon et son précurseur se révèlent être, par ailleurs, d'excellents outils synthétiques et permettront notamment une préparation extrêmement commode de cétones sulfonylées en position 2
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SCHMIDT, FREDERIC. "Syntheses et proprietes d'un recepteur macrocyclique a parois planes et d'elements structuraux plans derives de l'anthracene et de la phenazine." Paris 6, 1988. http://www.theses.fr/1988PA066530.

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Synthese d'un macrocycle forme de deux sous-unites phenazines substituees en 2,7 et maintenues face a face par des ponts diacetyleniques; interactions des chlorures de ces composes avec des molecules planes telles que le terephtalate, le naphtalenedicarboxylate-2,6 et des polynucleotides
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Belotti, Damien. "Cyclisation photoreductrice de cetones insaturees, applications : syntheses totales de l'hirsutene et de l'actinidine." Reims, 1988. http://www.theses.fr/1988REIMS006.

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L'irradiation de cetones delta ,epsilon -insaturees en presence de donneurs d'electrons tels que l'hmpt et la triethylamine donne une cyclisation photoreductrice menant a des cyclopentanols. Generalisation de cette reaction a des cetoamides : obtention d'aza-3 bicyclo(4. 3. 0) nonanes
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Charpentier, Langlois Patricia. "Activation d'une réaction entre un acide et une amine par reconnaissance moléculaire. Synthèse d'un récepteur d'amine." Rouen, 1995. http://www.theses.fr/1995ROUES027.

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Notre objectif a été de définir un récepteur hétérocyclique susceptible de faciliter, de manière générale, la réaction entre un acide carboxylique et une amine afin de conduire à un amide. La première partie de ce travail a consisté en l'examen de diverses stratégies d'approche de la partie tricyclique du récepteur. Nous nous sommes notamment intéressés à des dérivés de la tétrahydroisoquinoléine. A cette occasion, nous avons été amenés à apporter une contribution intéressante à la chimie de ce type de dérivés. Dans une seconde partie, nous nous sommes attachés à synthétiser la partie simplifi
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Luzi, Stefan Emanuel. "Phagemid display of bicyclic peptides." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648903.

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Tallon, Valérie. "Fonctionnalisation des quinoxalines et des cinnolines par réaction d'ortho-métallation." Rouen, 1996. http://www.theses.fr/1996ROUES041.

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La préparation de plusieurs quinoxalines et cinnolines, et en particulier une nouvelle synthèse de la 4-hydroxycinnoline ont été réalisées. Ce travail décrit la fonctionnalisation de la partie hétérocyclique de diverses quinoxalines et cinnolines par la réaction de métallation. La possibilité de métallation sur le cycle benzénique, en péri de l'azote, a aussi été montrée sur les cinnolines, avec l'iode et le chlorure de triméthylsilyle comme électrophiles. Enfin l'interêt de cette réaction de métallation est illustré par la préparation de xanthones et de diazépines.
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Fort, Yves. "Nouvelles applications des réducteurs complexes et étude de leur réactivité." Nancy 1, 1987. http://www.theses.fr/1987NAN10172.

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L'adjonction de chlorotriméthylsilane a un réducteur complexe au nickel conduit à de nouveaux systèmes notés NiRC-Si dont les propriétés réductrices ont été étudiées. La réduction régiosélective d'époxydes par les réducteurs complexes au nickel et au zinc a été développée. Il a été montré que les NIRC-L (réducteurs complexes préparés en présence de ligand) sont d'excellents agents de désulfuration d'hétérocycles contenant du soufre et un autre hétéroatome. Mécanisme des réductions
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Bédat, Joëlle. "Synthèses et études spectroscopiques de modèles biomimétiques chiraux du NADH : évaluation des facteurs conformationnels qui gouvernent le transfert énantiosélectif de l'hydrogène." Rouen, 1995. http://www.theses.fr/1995ROUES024.

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L'objectif de ce travail était d'évaluer les paramètres importants responsables des excès énantiomériques obtenus par des modèles biométiques chiraux du NADH. Cette stéréodifférenciation serait le fruit d'une synergie entre l'orientation de la fonction carbonyle et l'encombrement stérique du à l'auxiliaire chiral. Cette étude nous a, de plus, permis d'élaborer deux des modèles chiraux du NADH les plus performants en synthèse asymétrique. Dans une seconde partie, nous avons envisagé la synthèse de modèles plus stables et plus réactifs en série benzo[b]naphthyridine et indolo[2,3-b]pyridine
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Books on the topic "Bicyclic compound"

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Lednicer, Daniel. The organic chemistry of drug synthesis. Wiley, 1995.

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Lednicer, Daniel. The organic chemistry of drug synthesis. Wiley, 1990.

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Ian, Fryer R., ed. Bicyclic diazepines: Diazepines with an additional ring. Wiley, 1991.

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Fryer, R. Ian. Volume 50, Bicyclic Diazepines: Diazepines with an Additional Ring. Wiley-Interscience, 1991.

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Lednicer, Daniel. Organic Chemistry of Drug Synthesis. Wiley & Sons, Incorporated, John, 2007.

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Lednicer, Daniel, and Lester A. Mitscher. Volume 4, The Organic Chemistry of Drug Synthesis. Wiley-Interscience, 1990.

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Lednicer, Daniel. Organic Chemistry of Drug Synthesis. Wiley & Sons, Incorporated, John, 2013.

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Book chapters on the topic "Bicyclic compound"

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Fryer, R. Ian, and A. Walser. "Bicyclic 1,2-Diazepines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187371.ch1.

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Fryer, R. Ian, and A. Walser. "Bicyclic 1,3-Diazepines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187371.ch2.

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Whitesell, James K., and Mark A. Minton. "Mono- and Bicyclic Systems." In Stereochemical Analysis of Alicyclic Compounds by C-13 NMR Spectroscopy. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3161-9_3.

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Klärner, Frank-Gerrit. "Walk Rearrangements in [n.1.0] Bicyclic Compounds." In Topics in Stereochemistry. John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470147245.ch1.

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Whitesell, James K., and Mark A. Minton. "Bicyclo[3.2.0]heptanes." In Stereochemical Analysis of Alicyclic Compounds by C-13 NMR Spectroscopy. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3161-9_10.

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Whitesell, James K., and Mark A. Minton. "Bicyclo[3.2.1]octanes." In Stereochemical Analysis of Alicyclic Compounds by C-13 NMR Spectroscopy. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3161-9_11.

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Whitesell, James K., and Mark A. Minton. "Bicyclo[3.2.2]nonanes." In Stereochemical Analysis of Alicyclic Compounds by C-13 NMR Spectroscopy. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3161-9_12.

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Whitesell, James K., and Mark A. Minton. "Bicyclo[3.3.0]octanes." In Stereochemical Analysis of Alicyclic Compounds by C-13 NMR Spectroscopy. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3161-9_13.

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Whitesell, James K., and Mark A. Minton. "Bicyclo[4.1.0]heptanes." In Stereochemical Analysis of Alicyclic Compounds by C-13 NMR Spectroscopy. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3161-9_15.

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Whitesell, James K., and Mark A. Minton. "Bicyclo[4.2.0]octanes." In Stereochemical Analysis of Alicyclic Compounds by C-13 NMR Spectroscopy. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3161-9_16.

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Conference papers on the topic "Bicyclic compound"

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Castro, C., E. A. Dixon, N. Ibrahim, et al. "The Vibrational Spectra Of Selected Bicyclic Compounds." In 1985 International Conference on Fourier and Computerized Infrared Spectroscopy, edited by David G. Cameron and Jeannette G. Grasselli. SPIE, 1985. http://dx.doi.org/10.1117/12.970820.

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Doria, Alberto, and Matteo Formentini. "Identification of the Structural Modes of High Performance Bicycles in the Perspective of Wobble Control." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-47030.

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Most of researches in the field of bicycle dynamics deal with auto-stabilization and rider control by means of steer-torque and lean-torque. Bicycle models composed by rigid bodies with thin wheels making point contact with the road and rolling without any slip are suited for carrying out these studies. Numerical analysis of stability by means of these models leads to the capsize, castering and weave modes, which make it possible to understand many aspects of bicycle dynamics. However, some high performance bicycles at high speed show dangerous wobble oscillations. Cyclists’ experience and rec
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Petrone, Nicola, and Francesco Trabacchin. "Development of a Test Bench for the Subjective and Objective Evaluation of the Vibrational Comfort of Bicycle Components." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-34869.

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Vibrational comfort is one of the most important parameters evaluated by cyclists and it is correlated to the response of bicycle components in combination with the cyclist’s characteristics. Vibration transmissibility of wheels and saddles had been recently studied during lab tests using a wooden dummy bottom resting on the saddle and in road tests on an instrumented racing bicycle at different speeds on different surfaces. In this study, a test bench was developed in order to simulate different vibrational inputs to the seatpost from the road surface on a group of real cyclists during steady
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Ito, Teruaki. "Intuition-Based Browsing Interaction Towards Emotional Design." In ASME 2008 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/detc2008-49456.

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Emotional qualities such as the product’s aesthetics are regarded as critical factors in mature products. In the mean time, the products, whichever they are matured or not, must satisfy the functional requirements from the customers considering the technical constraints. For emotional designing, the designer’s view point towards the design object plays a very critical role. However, those views are not well taken care of in the conventional design support tools. The author proposed the idea of perspective browsing, where the designer’s viewpoint is represented as “Perspective”. There can be a
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Doria, Alberto, and Mauro Tognazzo. "Identification of the Biomechanical Parameters of the Riders of Two-Wheeled Vehicles by Means of Vibration Testing." In ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-70054.

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In bicycles and motorcycles the mass of the rider is a relevant share of the total mass and the passive response of the rider’s body to vibrations influences the dynamics and stability of the whole system. Therefore advanced models of two-wheeled vehicles have to include a passive biomechanical model of the rider. This paper focuses on the development of biomechanical models able to simulate the response of the rider to yaw and steer oscillations and on the identification of the rider’s body mechanical properties. Rider models composed by some rigid bodies with lumped stiffness and damping ele
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Vallee, Glenn E. "Implementation of Multi-Year Product Innovation Projects." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-36443.

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A methodology and case study detailing the implementation of multi-year product innovation projects is presented. A product called the Waterboy, an inexpensive water purification system designed for under developed countries, was developed by three different groups of students over a span of two years. The initial concept was first developed by a six member entrepreneurial team composed of senior level business and engineering students enrolled in a one semester Product Innovation and Development course. This team was responsible assessing the market need, determining product requirements and
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