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1

Solano-Aguilar, Gloria, Harry Dawson, Marta Restrepo, Kate Andrews, Bryan Vinyard, and Joseph F. Urban. "Detection of Bifidobacterium animalis subsp. lactis (Bb12) in the Intestine after Feeding of Sows and Their Piglets." Applied and Environmental Microbiology 74, no. 20 (2008): 6338–47. http://dx.doi.org/10.1128/aem.00309-08.

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ABSTRACT A real-time PCR method has been developed to distinguish Bifidobacterium animalis subspecies in the gastrointestinal tracts of pigs. Identification of a highly conserved single-copy tuf gene encoding the elongation factor Tu involved in bacterial protein biosynthesis was used as a marker to differentiate homologous Bifidobacterium animalis subsp. lactis (strain Bb12) from Bifidobacterium animalis subsp. animalis, as well as Bifidobacterium suis, Bifidobacterium breve, Bifidobacterium longum, several species of Lactobacillus, and Enterococcus faecium. Real-time PCR detection of seriall
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Lisová, I., Š. Horáčková, R. Kováčová, V. Rada, and M. Plocková. "Emulsion encapsulation of Bifidobacterium animalis subsp. lactis Bb12 with the addition of lecithin." Czech Journal of Food Sciences 31, No. 3 (2013): 270–74. http://dx.doi.org/10.17221/188/2012-cjfs.

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The commercial probiotic strain Bifidobacterium animalis subsp. lactis Bb12 was encapsulated using emulsion encapsulation into milk protein matrix without and with the addition of 0.5% w/w lecithin into the oil. Different agitation speeds were used during the encapsulation process. The examination of microcapsules was carried out by optical microscope and fluorescence in situ hybridisation. The particle size distribution as volume based median d<sub>0.5</sub> was evaluated by the laser diffraction method. In the case of no lecithin addition, the agitation speed did not influence si
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Kumherová, Monika, Kristina Veselá, Kateřina Jokešová, Iveta Klojdová, and Šárka Horáčková. "Influence of co-encapsulation of Bifidobacterium animalis subsp. lactis Bb12 with inulin and ascorbic acid on its viability." Czech Journal of Food Sciences 38, No. 1 (2020): 57–62. http://dx.doi.org/10.17221/292/2019-cjfs.

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Eight types of capsules containing Bifidobacterium animalis subsp. lactis Bb12 with addition of inulin and/or ascorbic acid were prepared by emulsion method with milk protein matrix or by extrusion method with alginate matrix. The size of protein and alginate capsules containing only Bb12 was 204 ± 18 µm and 1.7 ± 0.1 mm, respectively. Addition of both inulin (1% w/w) and ascorbic acid (0.5% w/w) increased the size of alginate capsules. Both methods of encapsulation prevented efficiently the manifestation of Bb12 cell metabolic activity. All types of encapsulation provided higher resistance of
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Alhaj, Omar A., Ara D. Kanekanian, Adrian C. Peters, and Arthur S. Tatham. "Hypocholesterolaemic effect of Bifidobacterium animalis subsp. lactis (Bb12) and trypsin casein hydrolysate." Food Chemistry 123, no. 2 (2010): 430–35. http://dx.doi.org/10.1016/j.foodchem.2010.04.061.

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5

Splichal, Igor, Sharon M. Donovan, Zdislava Kindlova, et al. "Release of HMGB1 and Toll-like Receptors 2, 4, and 9 Signaling Are Modulated by Bifidobacterium animalis subsp. lactis BB-12 and Salmonella Typhimurium in a Gnotobiotic Piglet Model of Preterm Infants." International Journal of Molecular Sciences 24, no. 3 (2023): 2329. http://dx.doi.org/10.3390/ijms24032329.

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Gnotobiotic (GN) animals with defined microbiota allow us to study host–microbiota and microbiota–microbiota interferences. Preterm germ-free (GF) piglets were mono-associated with probiotic Bifidobacterium animalis subsp. lactis BB-12 (BB12) to ameliorate/prevent the consequences of infection with the Salmonella Typhimurium strain LT2 (LT2). Goblet cell density; expression of Toll-like receptors (TLRs) 2, 4, and 9; high mobility group box 1 (HMGB1); interleukin (IL)-6; and IL-12/23p40 were analyzed to evaluate the possible modulatory effect of BB12. BB12 prevented an LT2-induced decrease of g
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Šárka, Horáčková, Rokytová Kristýna, Bialasová Kristina, Klojdová Iveta, and Sluková Marcela. "Fruit juices with probiotics – new type of functional foods." Czech Journal of Food Sciences 36, No. 4 (2018): 284–88. http://dx.doi.org/10.17221/39/2018-cjfs.

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The cells of commercial strain Bifidobacterium animalis subsp. lactis Bb12 were encapsulated using emulsion encapsulation in a milk protein matrix. The volume based median of the microcapsules was 52.1 ± 6.2 µm. The stability of free and encapsulated cells was compared during 28 day-storage in pineapple juice and in strawberry-apple juice at 8 ± 1°C and 22 ± 1°C. Encapsulation ensured a higher number of cells compared to the free cells only at 8 ± 1°C. Strawberry-apple juice was found to be not suitable as probiotic vehicle. Both free and encapsulated cells lost their viability after 14 days a
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Yahla, Imene, Hasnia Ziar, Mohamed Benali, and Ali Riazi. "Bacterial Conjugated Linoleic Acid Effect on Hepatic and Adipose Tis-sues of High-Fat diet-Induced Obese Rats." South Asian Journal of Experimental Biology 6, no. 4 (2016): 143–49. http://dx.doi.org/10.38150/sajeb.6(4).p143-149.

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The aim of the present study is to background the effect of conjugated lino-leic acid isomers (CLA) produced by two probiotic strains, Lactobacillus rham-nosus LBRE-LSAS (a human originated bacterium) and Bifidobacterium ani-malis subsp lactis Bb12, on both hepatic and adipose tissues of high-fat diet fed Wistar rats. Five-week-old male Wistar rats were divided into 4 groups (n=6) fed a high-fat diet for three of them (control and supplemented with 1x109 CFU per rat of LBRE-LSAS or Bb12 strain and 1.4% of free linoleic acid; designed as treated rats) and a standard diet for the fourth group. A
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8

Anania, Caterina, Vincenza Patrizia Di Marino, Francesca Olivero, et al. "Treatment with a Probiotic Mixture Containing Bifidobacterium animalis Subsp. Lactis BB12 and Enterococcus faecium L3 for the Prevention of Allergic Rhinitis Symptoms in Children: A Randomized Controlled Trial." Nutrients 13, no. 4 (2021): 1315. http://dx.doi.org/10.3390/nu13041315.

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Background: Probiotics may prevent the allergic response development due to their anti-inflammatory and immunomodulatory effects. The aim of this study is to determine if the prophylactic treatment with a mixture of Bifidobacterium animalis subsp. Lactis BB12 and Enterococcus faecium L3 would reduce symptoms and need for drug use in children with allergic rhinitis (AR). Methods: The study included 250 children aged from 6 to 17 years, affected by AR. Patients were randomly assigned to the intervention group (150) or to the placebo group (100). Patients in the intervention group, in addition to
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9

Splichalova, Alla, Sharon M. Donovan, Helena Tlaskalova-Hogenova, Zbynek Stranak, Zdislava Splichalova, and Igor Splichal. "Monoassociation of Preterm Germ-Free Piglets with Bifidobacterium animalis Subsp. lactis BB-12 and Its Impact on Infection with Salmonella Typhimurium." Biomedicines 9, no. 2 (2021): 183. http://dx.doi.org/10.3390/biomedicines9020183.

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Preterm germ-free piglets were monoassociated with probiotic Bifidobacterium animalis subsp. lactis BB-12 (BB12) to verify its safety and to investigate possible protection against subsequent infection with Salmonella Typhimurium strain LT2 (LT2). Clinical signs of salmonellosis, bacterial colonization in the intestine, bacterial translocation to mesenteric lymph nodes (MLN), blood, liver, spleen, and lungs, histopathological changes in the ileum, claudin-1 and occludin mRNA expression in the ileum and colon, intestinal and plasma concentrations of IL-8, TNF-α, and IL-10 were evaluated. Both B
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10

Hyrslova, Ivana, Gabriela Krausova, Jana Smolova, et al. "Functional Properties of Chlorella vulgaris, Colostrum, and Bifidobacteria, and Their Potential for Application in Functional Foods." Applied Sciences 11, no. 11 (2021): 5264. http://dx.doi.org/10.3390/app11115264.

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The market for new functional foods and food supplements is rapidly evolving, with a current emphasis on using natural sources. Algae, probiotics, and colostrum are rich sources of nutrients and bioactive compounds with positive effects on human and animal health. To determine the potential for developing new functional foods combining these components, we evaluated their synergistic effects. We assessed the growth of selected bifidobacteria in a medium supplemented with Chlorella vulgaris and its immunomodulatory and cytotoxic effects on the human peripheral mononuclear cells and colon cancer
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11

Harata, Gaku, Kazutoyo Yoda, Ruipeng Wang, et al. "Species- and Age/Generation-Dependent Adherence of Bifidobacterium bifidum to Human Intestinal Mucus In Vitro." Microorganisms 9, no. 3 (2021): 542. http://dx.doi.org/10.3390/microorganisms9030542.

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Adhesion to intestinal mucus is the first event in the process by which intestinal microbes colonize the intestine. It plays a critical role in the initiation of interactions between gut microbes and host animals. Despite the importance, the adhesion properties of probiotics are generally characterized using porcine mucin; adhesion to human mucus has been poorly characterized. In the present study, human intestinal mucus samples were isolated from 114 fecal samples collected from healthy infants and adults. In initial screening, four out of the 13 beneficial microbes tested, including the type
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12

Chaves, Fernanda M., Igor L. Baptista, Fernando M. Simabuco, et al. "High-intensity-exercise-induced intestinal damage is protected by fermented milk supplemented with whey protein, probiotic and pomegranate (Punica granatum L.)." British Journal of Nutrition 119, no. 8 (2018): 896–909. http://dx.doi.org/10.1017/s0007114518000594.

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AbstractHere we evaluated the effect of fermented milk supplemented with whey protein (approximately 80 % protein), probiotic (Bifidobacterium animalis subsp. lactis BB12) and pomegranate juice (Punica granatum L.) on the physical performance, intestinal motility and villi structure, inflammatory markers and intestinal microbiota of rats under high-intensity acute exercise. In all, twenty-four Wistar rats were separated into groups: control (Ctrl), supplemented (Supp), exercised (Exe) and exercised and supplemented (Exe+Supp). Rats in the Supp groups received fermented milk during 6 weeks by o
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13

Skenderidis, Prodromos, Chrysanthi Mitsagga, Dimitrios Lampakis, Konstantinos Petrotos, and Ioannis Giavasis. "The Effect of Encapsulated Powder of Goji Berry (Lycium barbarum) on Growth and Survival of Probiotic Bacteria." Microorganisms 8, no. 1 (2019): 57. http://dx.doi.org/10.3390/microorganisms8010057.

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The aim of the present work was to investigate the potential prebiotic action of Goji berry powder on selected probiotic bacteria grown in a nutritive synthetic substrate and in simulated gastric and intestinal juices. Different probiotic strains of Bifidobacterium and Lactobacillus were grown in these substrates with or without the addition of encapsulated goji berry extracts of different polysaccharide and polyphenol contents. The results proved that the addition of the extracts promoted the proliferation of probiotic strains and, in particular, increased the number of bacterial colonies of
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14

Božanić, R., S. Lovković, and I. Jeličić. "Optimising fermentation of soymilk with probiotic bacteria." Czech Journal of Food Sciences 29, No. 1 (2011): 51–56. http://dx.doi.org/10.17221/97/2010-cjfs.

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Soymilk was fermented with probiotic culture ABT5 and yoghurt culture with the addition of bifidobacteria at different temperatures (37°C and 42°C) with the aim of shortening the fermentation time and producing a probiotic fermented soymilk. During the fermentation and storage of the fermented soymilk (28 days at +4°C), the changes in pH-value and viable cells count were observed. Incubation temperature did not affect significantly fermentation time (7 h at 42°C and 8 h at 37°C, respectively), with ABT5 culture (Lactobacillus acidophilus, Bifidobacterium
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15

Keddari, Soumia, Iyas Aldib, and Ali Riazi. "In vivo stimulatory effects of wheat bran on intestinal microbial ecosystem of mice." South Asian Journal of Experimental Biology 4, no. 1 (2014): 24–32. http://dx.doi.org/10.38150/sajeb.4(1).p24-32.

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The prebiotic effect in vivo of wheat bran on growth and colonization of both strains bifidobacteria (Bifidobacterium animalis subsp lactis Bb12 and B. bifi-dum Bb 443) and two lactic strains (Lactobacillus acidophilus LbA - CEC-T4529; L.rhamnosus LBRE - LSAS) was investigated. Conventional Swiss mice received a daily dose of orogastric monocultures of different strains tested for 4 weeks. These mice were fed a diet supplemented with or without wheat bran by weight. Changes in weight, implantation of strains and modifi-cation of microflora were monitored throughout the study. At the end of the
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16

Ziar, Hasnia, Philippe Gérard, and Ali Riazi. "CLA-Producing Probiotics for the Development of a Yogurt-Type Beverage." Beverages 11, no. 2 (2025): 50. https://doi.org/10.3390/beverages11020050.

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This study examined the ability of four beneficial strains (Lactobacillus rhamnosus LbRE-LSAS, Bifidobacterium animalis subsp. lactis Bb12, and two yogurt starters TA040 and LB340) to ferment MRS or milk containing free linoleic acid (0, 0.5, or 1 mg/mL). The goal was to produce an enriched conjugated linoleic acid (CLA) isomers’ yogurt-type beverage. Linoleic acid (LA) at 0.5 mg/mL did not interfere with the growth of the assayed bacteria on de Man Rogosa and Sharpe broth (MRS) or milk. On the other hand, increasing the content of LA in the MRS or yogurt-type beverage to 1 mg/mL slightly inhi
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17

Du, Xue, Jessica Rodriguez, and Josephine Wee. "Dietary Postbiotics Reduce Cytotoxicity and Inflammation Induced by Crystalline Silica in an In Vitro RAW 264.7 Macrophage Model." Foods 11, no. 6 (2022): 877. http://dx.doi.org/10.3390/foods11060877.

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Crystalline silica (cSiO2) particles are naturally existing environmental toxicants. Exposure to cSiO2 could cause local or systemic inflammation and aggregate inflammation-associated diseases. Dietary postbiotics are reported to possess anti-inflammatory activities; however, their effects on cSiO2-triggered inflammation are unknown. Here, we investigate the impact of postbiotics from Lacticaseibacillus rhamnosus (LGG), Limosilactobacillus reuteri (L.reu), and Bifidobacterium animalis subsp. lactis Bb12 (BB12) on cSiO2-induced cytotoxicity and IL-1 cytokines in vitro using macrophages. The pos
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18

Chae, Jung Min, Wan Heo, Hyung Taek Cho, et al. "Effects of Orally-Administered Bifidobacterium animalis subsp. lactis Strain BB12 on Dextran Sodium Sulfate-Induced Colitis in Mice." Journal of Microbiology and Biotechnology 28, no. 11 (2018): 1800–1805. http://dx.doi.org/10.4014/jmb.1805.05072.

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19

Yuliani, Kartika, Nyoman Kertia, and Lily Arsanti Lestari. "Efek konsumsi yoghurt probiotik terhadap kadar low density lipoprotein pada penyandang diabetes mellitus tipe 2." Jurnal Gizi Indonesia 8, no. 1 (2020): 69. http://dx.doi.org/10.14710/jgi.8.1.69-74.

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Background : As one of important markers of cardiovascular complication in patients with type 2 diabetes mellitus, low density lipoprotein (LDL) shall be maintained to be in normal range. Based on previous research, consumption of probiotic yogurt contains Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis is presumed can improve LDL in patients with type 2 diabetes mellitus but the scientific evidence is still few.Objectives: To investigate the effect of probiotic yogurt on LDL in patients with type 2 diabetes.Methods: This study was double blinded randomized controlled tria
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Lesniewska, Violetta, Ian Rowland, Patrice D. Cani, Audrey M. Neyrinck, Nathalie M. Delzenne, and Patrick J. Naughton. "Effect on Components of the Intestinal Microflora and Plasma Neuropeptide Levels of Feeding Lactobacillus delbrueckii, Bifidobacterium lactis, and Inulin to Adult and Elderly Rats." Applied and Environmental Microbiology 72, no. 10 (2006): 6533–38. http://dx.doi.org/10.1128/aem.00915-06.

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ABSTRACT The aim of this study was to compare the effects of the mixture of Lactobacillus delbrueckii subsp. rhamnosus strain GG, Bifidobacterium lactis Bb12, and inulin on intestinal populations of lactobacilli, bifidobacteria, and enterobacteria in adult and elderly rats fed the same (in quality and quantity) diet. The portal plasma levels of two neuropeptides, neuropeptide Y (NPY) and peptide YY (PYY), were also evaluated to assess the physiological consequences of the synbiotic treatment for the gastrointestinal (GI) tracts of rats of different ages. Adult (n = 24) and elderly (n = 24) mal
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Gómez, E., F. Martín, A. M. Nogacka, et al. "Impact of probiotics on development and behaviour in Drosophila melanogaster – a potential in vivo model to assess probiotics." Beneficial Microbes 10, no. 2 (2019): 179–88. http://dx.doi.org/10.3920/bm2018.0012.

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In vitro models are frequently used in probiotic research. However, such models often fail to predict in vivo functionality and efficacy. This fact complicates the screening process for selecting the most suitable strains, prior to accomplish expensive animal studies and clinical intervention trials. Therefore, additional sensitive, discriminating and cost-effective models are needed to conduct preliminary assays before undertaking human intervention studies definitely proving efficacy. With this purpose in mind, we explored the potential of axenic Drosophila melanogaster populations as well a
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Ünal, Gülfem. "Microbiological, antioxidant, and sensory properties of probiotic yoghurt enriched with different strawberry varieties." Mljekarstvo 75, no. 1 (2025): 41–51. https://doi.org/10.15567/mljekarstvo.2025.0104.

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The influence of different strawberry varieties on the microbiological, antioxidant and sensory properties of probiotic yoghurt, containing Bifidobacterium animalis subsp. lactis Bb12, were monitored for 21 days. For this purpose, strawberry pulp (15 %) containing strawberry and sugar in a 1:1 ratio was used in the yoghurt formulation. Higher total phenolic content and ferric reducing antioxidant power (FRAP) were detected in Albion and Camarosa varieties than Rubygem whereas Albion variety had the highest total anthocyanin content (p<0.05). Colour parameters (L*, a*, b*) of probiotic yoghu
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23

Mantziari, Anastasia, Juhani Aakko, Himanshu Kumar, et al. "The Impact of Storage Conditions on the Stability of Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis Bb12 in Human Milk." Breastfeeding Medicine 12, no. 9 (2017): 566–69. http://dx.doi.org/10.1089/bfm.2017.0051.

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Tomasik, Jakub, Robert H. Yolken, Sabine Bahn, and Faith B. Dickerson. "Immunomodulatory Effects of Probiotic Supplementation in Schizophrenia Patients: A Randomized, Placebo-Controlled Trial." Biomarker Insights 10 (January 2015): BMI.S22007. http://dx.doi.org/10.4137/bmi.s22007.

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Although peripheral immune system abnormalities have been linked to schizophrenia pathophysiology, standard antipsychotic drugs show limited immunological effects. Thus, more effective treatment approaches are required. Probiotics are microorganisms that modulate the immune response of the host and, therefore, may be beneficial to schizophrenia patients. The aim of this study was to examine the possible immunomodulatory effects of probiotic supplementation in chronic schizophrenia patients. The concentrations of 47 immune–related serum proteins were measured using multiplexed immunoassays in s
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Ermolenko, K. D., S. E. Ukraintsev, N. P. Gladysheva, E. A. Martens, L. I. Zhelezova, and E. I. Ermolenko. "Antagonistic activity of probiotics in campylobacteriosis." Voprosy detskoj dietologii 21, no. 5 (2023): 24–32. http://dx.doi.org/10.20953/1727-5784-2023-5-24-32.

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Campylobacter species are globally recognized as the most common causative agents of acute intestinal infections. In recent years, Campylobacter spp. have become increasingly resistant to antibiotics, necessitating the search for new methods of treatment. Objective. To evaluate the antagonistic activity of different probiotics and autoprobiotic enterococci against Campylobacter spp. Materials and methods. Clinical isolates of Campylobacter coli and Campylobacter jejuni were obtained from the microbial culture collection in the Pediatric Research and Clinical Center for Infectious Diseases, Sai
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Amiri, Saber, Reza Rezaei Mokarram, Mahmoud Sowti Khiabani, Mahmoud Rezazadeh Bari, and Mohammad Alizadeh Khaledabad. "Exopolysaccharides production by Lactobacillus acidophilus LA5 and Bifidobacterium animalis subsp. lactis BB12: Optimization of fermentation variables and characterization of structure and bioactivities." International Journal of Biological Macromolecules 123 (February 2019): 752–65. http://dx.doi.org/10.1016/j.ijbiomac.2018.11.084.

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Hao, Linlin, Yinxue Liu, Ignatius Man-Yau Szeto, et al. "Milk Exosome-Based Delivery System for Probiotic Encapsulation That Enhances the Gastrointestinal Resistance and Adhesion of Probiotics." Nutrients 17, no. 5 (2025): 923. https://doi.org/10.3390/nu17050923.

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The oral administration of probiotics is a promising strategy to regulate the host–intestinal flora balance and improve health. Nevertheless, adverse gastrointestinal (GI) conditions affect the activity of free native probiotics. In this study, a novel probiotic encapsulation system based on milk exosomes (mExos) and DSPE-PEG-PBA was developed. mExos acted as a shield to protect probiotics from harsh GI environments, and DSPE-PEG-PBA served as a bridge between mExos and probiotics. The coated probiotics were characterized by transmission electron microscopy (TEM), Fourier transform infrared sp
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Mantziari, Anastasia, Enni Mannila, Maria Carmen Collado, Seppo Salminen, and Carlos Gómez-Gallego. "Exogenous Polyamines Influence In Vitro Microbial Adhesion to Human Mucus according to the Age of Mucus Donor." Microorganisms 9, no. 6 (2021): 1239. http://dx.doi.org/10.3390/microorganisms9061239.

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Adhesion to intestinal mucus is the first step for microbiota colonization in early life. Polyamines are polycations with important physiological functions in both procaryotic and eucaryotic cells. However, their role in intestinal mucus adhesion is not known. The objective of the present study was to evaluate whether exogenous polyamines (putrescine, spermidine, spermine, and their combination) would alter the adhesive properties of Lacticaseibacillus rhamnosus GG (LGG), Bifidobacterium animalis subs. lactis Bb12, Cronobacter sakazakii, and Escherichia coli. Human intestinal mucus was isolate
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Rahali, Abdallah, Mounira Ariech, Badreddine Moussaoui, and Ali Riazi. "Encapsulation effects of galactomannans combined with xanthan on the survival of two lactic strains under simulated digestive hostilities." European Journal of Biological Research 12, no. 3 (2022): 262–70. https://doi.org/10.5281/zenodo.7048634.

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Galactomannans are the main component of locust bean gum from the fruit of the carob tree, <em>Ceratonia siliqua </em>L. They are a reserve of polysaccharides, found in the translucent endosperm of the seeds. They are designated as the best gels with thickening capacity and are, therefore, widely used as a natural food additive (E410) in many food, pharmaceutical and cosmetic preparations. In this study, we aim to exploit this gelling property of carob galactomannans in the microencapsulation of lactic bacteria in order to protect them from the negative effects of simulated digestive condition
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Ziar, Hasnia, Imène Yahla, Meryem Sadoud, et al. "Association of carob galactomannans with probiotic bacteria in synbiotic fermented milk and colon targeted-release carrier." International Food Research Journal 29, no. 4 (2022): 879–91. http://dx.doi.org/10.47836/ifrj.29.4.15.

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For the first time, this study presented the use of raw locust bean gum (LBG) as a prebiotic, with one probiotic strain in synbiotic fermented milk or combined with Na-alginate as a biopolymer, for a targeted release of bacteria under colon-like conditions. For this purpose, the fermentative characteristics (biomass, pH), bacterial survival, and developed viscosities of the stored fermented milks were determined. The survival rates of microencapsulated bacteria using the emulsion technique under simulated gastrointestinal conditions (stomach: pH 2 + 0.3% pepsin; colon: pH 6.5 + 1% pancreatin +
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Fino, Luciana Carvalho, Fabíola Lima Pena, Maria Carolina Pelatieri Valle, Thais Ramos Silva, Vivian Cristina Cruz Rodrigues, and Adriane Costa Antunes. "Digestão Simulada de Bebida Esportiva Contendo Diferentes Probióticos." Ensaios e Ciência C Biológicas Agrárias e da Saúde 24, no. 1 (2020): 47–53. http://dx.doi.org/10.17921/1415-6938.2020v24n1p47-53.

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O exercício físico de alta intensidade está relacionado com diversas alterações sistêmicas que podem prejudicar a performance do indivíduo, tais como: a queda da imunidade, a perda de massa muscular, a insônia, entre outros. Os probióticos, quando administrados regularmente para esse público, podem reduzir os sintomas relacionados ao overtraining. O presente estudo buscou selecionar uma cepa probiótica para empregar em uma bebida esportiva (a base de leite fermentado), contendo elevada quantidade de compostos fenólicos e adicionada de cepas probióticas, sendo utilizadas como principal critério
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Akkaya, Müctebanur. "Effect of different drying methods on the quality attributes of probiotic-enriched cheese chips." Mljekarstvo 75, no. 3 (2025): 146–59. https://doi.org/10.15567/mljekarstvo.2025.0302.

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In this study, the possibilities of producing probiotic-enriched cheese chips from White cheese (fresh) using various drying methods including natural air drying at 25 °C for 24 hours, microwave drying at 180 W for 120 seconds, and tray drying at 25 °C for 4 hours with an air velocity of 1.3 m/s were investigated. The aim was to examine the effects of different drying systems used in production on the viability of probiotic bacteria (Lactobacillus acidophilus (LA-5) and Bifidobacterium animalis subsp. lactis (BB-12) and the quality characteristics of probiotic-enriched cheese chips. Physicoche
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Leong, Andrea, Zhiqian Liu, Hala Almshawit, et al. "Oligosaccharides in goats’ milk-based infant formula and their prebiotic and anti-infection properties." British Journal of Nutrition 122, no. 04 (2019): 441–49. http://dx.doi.org/10.1017/s000711451900134x.

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AbstractHuman milk contains an abundant supply and diverse array of oligosaccharides that are known to impart significant health benefits to the nursing infant including establishment and maintenance of a healthy gut microflora, immune development and protection against gastrointestinal infections. When breastfeeding is not possible or insufficient, infant formulas are commonly used as an alternative. However, limited information is available about the presence of naturally occurring oligosaccharides in these infant formulas and their likely health benefits. The present study examined the pres
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Ventura, Marco, and Ralf Zink. "Comparative Sequence Analysis of the tuf and recA Genes and Restriction Fragment Length Polymorphism of the Internal Transcribed Spacer Region Sequences Supply Additional Tools for Discriminating Bifidobacterium lactis from Bifidobacterium animalis." Applied and Environmental Microbiology 69, no. 12 (2003): 7517–22. http://dx.doi.org/10.1128/aem.69.12.7517-7522.2003.

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ABSTRACT The relationship between Bifidobacterium lactis and Bifidobacterium animalis was examined by comparative analysis of tuf and recA gene sequences and by restriction fragment length polymorphism analysis of their internal 16S-23S transcribed spacer region sequences. The bifidobacterial strains investigated could be divided into two distinct groups within a single species based on the tuf, recA, and 16S-23S spacer region sequence analysis. Therefore, all strains of B. lactis and B. animalis could be unified as the species B. animalis and divided into two subspecies, Bifidobacterium anima
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Utebaeva, Aidana, Viktoriia Yevlash, Eleonora Gabrilyants, Zhansaya Abish, and Aigerim Aitbayeva. "Development of kefir product with Bifidobacterium animalis subsp. lactis (BB-12) activated by Sanguisorba officinalis L. extract." Eastern-European Journal of Enterprise Technologies 5, no. 11 (131) (2024): 6–15. http://dx.doi.org/10.15587/1729-4061.2024.312708.

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This study addresses the challenge of enhancing the activation of Bifidobacterium animalis subsp. lactis (BB-12) to improve the quality and functionality of kefir-based products. The objective was to develop a kefir product enriched with Bifidobacterium animalis subsp. lactis, activated using an extract of Sanguisorba officinalis L., a natural antioxidant, to reduce activation time and boost probiotic efficacy. Two kefir samples were prepared: a control and an experimental product enriched with Bifidobacterium animalis subsp. lactis activated by Sanguisorba officinalis L. at 10⁻⁵ g/cm³ concent
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Janer, C., F. Arigoni, B. H. Lee, C. Peláez, and T. Requena. "Enzymatic Ability of Bifidobacterium animalis subsp. lactis To Hydrolyze Milk Proteins: Identification and Characterization of Endopeptidase O." Applied and Environmental Microbiology 71, no. 12 (2005): 8460–65. http://dx.doi.org/10.1128/aem.71.12.8460-8465.2005.

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ABSTRACT The proteolytic system of Bifidobacterium animalis subsp. lactis was analyzed, and an intracellular endopeptidase (PepO) was identified and characterized. This work reports the first complete cloning, purification, and characterization of a proteolytic enzyme in Bifidobacterium spp. Aminopeptidase activities (general aminopeptidases, proline iminopeptidase, X-prolyl dipeptidylaminopeptidase) found in cell extracts of B. animalis subsp. lactis were higher for cells that had been grown in a milk-based medium than for those grown in MRS. A high specific proline iminopeptidase activity wa
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Bottacini, Francesca, Fabio Dal Bello, Francesca Turroni, et al. "Complete Genome Sequence of Bifidobacterium animalis subsp. lactis BLC1." Journal of Bacteriology 193, no. 22 (2011): 6387–88. http://dx.doi.org/10.1128/jb.06079-11.

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Bifidobacterium animalis subsp. lactis BLC1 is a probiotic bacterium that is widely exploited by food industries as the active ingredient of various functional foods. Here we report the complete genome sequence of B. animalis subsp. lactis BLC1, which is expected to provide insights into the biology of this health-promoting microorganism and improve our understanding of its phylogenetic relatedness with other members of the B. animalis subsp. lactis taxon.
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Masco, Liesbeth, Marco Ventura, Ralf Zink, Geert Huys, and Jean Swings. "Polyphasic taxonomic analysis of Bifidobacterium animalis and Bifidobacterium lactis reveals relatedness at the subspecies level: reclassification of Bifidobacterium animalis as Bifidobacterium animalis subsp. animalis subsp. nov. and Bifidobacterium lactis as Bifidobacterium animalis subsp. lactis subsp. nov." International Journal of Systematic and Evolutionary Microbiology 54, no. 4 (2004): 1137–43. http://dx.doi.org/10.1099/ijs.0.03011-0.

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Borshchev, Yury Y., Inessa Y. Burovenko, Alena B. Karaseva, et al. "Probiotic Therapy with Lactobacillus acidophilus and Bifidobacterium animalis subsp. lactis Results in Infarct Size Limitation in Rats with Obesity and Chemically Induced Colitis." Microorganisms 10, no. 11 (2022): 2293. http://dx.doi.org/10.3390/microorganisms10112293.

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In this study, we investigated the effect of three different probiotics, namely, a combination of Lactobacillus acidophilus (LA–5) and Bifidobacterium animalis subsp. lactis (BB–12), Saccharomyces boulardii, and Enterococcus faecium L3 on myocardial infarct size in rats with diet-induced obesity (DIO) and chemically-induced colitis (CIC). Potential associations between the effects of probiotics on myocardial ischemia-reperfusion injury and gut microbiome patterns as well as the serum levels of pro- and anti-inflammatory cytokines, lipopolysaccharide, and short chain fatty acids were also studi
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Candela, Marco, Manuela Centanni, Jessica Fiori, et al. "DnaK from Bifidobacterium animalis subsp. lactis is a surface-exposed human plasminogen receptor upregulated in response to bile salts." Microbiology 156, no. 6 (2010): 1609–18. http://dx.doi.org/10.1099/mic.0.038307-0.

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Bifidobacterium animalis subsp. lactis lives in the gastrointestinal tract of most mammals, including humans. Recently, for the probiotic strain B. animalis subsp. lactis BI07, a dose-dependent plasminogen-binding activity was demonstrated and five putative plasminogen-binding proteins were identified. Here we investigated the role of surface DnaK as a B. animalis subsp. lactis BI07 plasminogen receptor. DnaK was visualized on the bacterial cell surface by transmission electron microscopy. The His-tagged recombinant DnaK protein showed a high affinity for human plasminogen, with an equilibrium
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Bozkurt, Hüseyin. "A NEW BACTERIAL TRANSFER THERAPY FOR IBD: ENDOSCOPIC BIFIDOBACTERIUM AND XYLOGLUCAN ADMINISTRATION." Inflammatory Bowel Diseases 27, Supplement_1 (2021): S37—S38. http://dx.doi.org/10.1093/ibd/izaa347.091.

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Abstract Ulcerative colitis (UC) pathogenesis includes the altered gut microbiota, environmental factors, and human immune and genetic predisposition. Recently, its association with reduced bifidobacteria quantity in the microbiota is reported.Xyloglucan, a plant based prebiotic oligosaccharide, causes increase in bifidobacteria quantity. In this article we share the results of our UC cases treated by intracolonic single dose administration of Bifidobacterium animalis subsp. Lactis and xyloglucan combination. Intracolonic single dose administration of 200 billion CFUs of Bifidobacterium animal
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S�nchez, Borja, Marie-Christine Champomier-Verg�s, Birgitte Stuer-Lauridsen, et al. "Adaptation and Response of Bifidobacterium animalis subsp. lactis to Bile: a Proteomic and Physiological Approach." Applied and Environmental Microbiology 73, no. 21 (2007): 6757–67. http://dx.doi.org/10.1128/aem.00637-07.

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ABSTRACT Bile salts are natural detergents that facilitate the digestion and absorption of the hydrophobic components of the diet. However, their amphiphilic nature makes them very inhibitory for bacteria and strongly influences bacterial survival in the gastrointestinal tract. Adaptation to and tolerance of bile stress is therefore crucial for the persistence of bacteria in the human colonic niche. Bifidobacterium animalis subsp. lactis, a probiotic bacterium with documented health benefits, is applied largely in fermented dairy products. In this study, the effect of bile salts on proteomes o
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Sidarenka, Anastasiya, Leonid Valentovich, and Galina Novik. "Evaluation of probiotic potential of Bifidobacterium animalis subsp. lactis strains: an in vitro study." EuroBiotech Journal 1, no. 2 (2017): 182–83. http://dx.doi.org/10.24190/issn2564-615x/2017/02.12.

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Abstract Probiotic potential of two bifidobacterial strains isolated from feces of healthy adults and identified as Bifidobacterium animalis subsp. lactis was evaluated using in vitro testing. The analyzed strains were able to ferment a broad spectrum of carbohydrates, produced bioactive exopolysaccharides, demonstrated high survival rate in model GIT conditions, under heat and oxidative stresses, inhibited growth of a wide range of pathogenic and opportunistic bacteria, and proved to be safe for biotechnological application. Based on the complex phenotypic characteristics tested, Bifidobacter
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Sun, Zhihong, Xia Chen, Jicheng Wang, et al. "Complete Genome Sequence of Probiotic Bifidobacterium animalis subsp. lactis Strain V9." Journal of Bacteriology 192, no. 15 (2010): 4080–81. http://dx.doi.org/10.1128/jb.00369-10.

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ABSTRACT Bifidobacterium animalis subsp. lactis strain V9 is a Chinese commercial bifidobacteria with several probiotic functions. It was isolated from a healthy Mongolian child in China. We present here the complete genome sequence of V9 and compare it to 3 other published genome sequences of B. animalis subsp. lactis strains. The result indicates the lack of polymorphism among strains of this subspecies from different continents.
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Carreras, N. López, P. Martorell, E. Chenoll, S. Genovés, D. Ramón, and A. Aleixandre. "Anti-obesity properties of the strain Bifidobacterium animalis subsp. lactis CECT 8145 in Zücker fatty rats." Beneficial Microbes 9, no. 4 (2018): 629–41. http://dx.doi.org/10.3920/bm2017.0141.

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We evaluated the effect of oral administration of Bifidobacterium animalis subsp. lactis CECT 8145 strain in Zücker fatty rats. The Zücker fatty rats were randomly divided into two groups (n=10 each) and administered either B. animalis subsp. lactis CECT 8145 (1010 cfu/day) suspended in skim milk, or skim milk alone (control group). Each treatment was administered in drinking bottles from week 5 until week 17 of age. A lean Zücker rat group (standard group) was included to provide normal values for the Zücker strain. This group was administered skim milk in the drinking bottle for the same exp
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Khavkin, A. I., M. M. Gurova, V. P. Novikova, and A. Yu Vashura. "Probiotics and probiotic products for children with intestinal disorders." Voprosy praktičeskoj pediatrii 17, no. 6 (2022): 97–105. http://dx.doi.org/10.20953/1817-7646-2022-6-97-105.

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This article outlines current concepts of probiotic drugs and probiotic foods for children, provides the list of gastrointestinal disorders in children that can be considered as indications for probiotics, as well as their mechanism of action. Particular attention is paid to probiotic use according to the criteria of evidence-based medicine. The review also focuses on the positive role of the probiotic strain Bifidobacterium animalis subsp. lactis in the treatment and prevention of gastroenterological disorders in children, both as part of pharmacotherapy and enriched food products. Key words:
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Bozkurt, Huseyin Sancar, and Banu Kara. "A new treatment for ulcerative colitis: Intracolonic Bifidobacterium and xyloglucan application." European Journal of Inflammation 18 (January 2020): 205873922094262. http://dx.doi.org/10.1177/2058739220942626.

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Ulcerative colitis (UC) pathogenesis includes the altered gut microbiota, environmental factors, and human immune and genetic predisposition. Recently, its association with reduced bifidobacteria quantity in the microbiota is reported. Xyloglucan, a plant-based prebiotic oligosaccharide, causes increase in bifidobacteria quantity. In this article, we share the results of our UC cases treated by intracolonic single-dose administration of Bifidobacterium animalis subsp. lactis and xyloglucan combination. Intracolonic single-dose administration of 200 billion colony-forming units (CFUs) of B. ani
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Bozkurt, Hüseyin. "P077 A NEW TREATMENT APPROACH FOR INFLAMMATORY BOWEL DISEASE: INTRACOLONIC BIFIDOBACTERIUM AND XYLOGLUCAN APPLICATION." Inflammatory Bowel Diseases 26, Supplement_1 (2020): S35—S36. http://dx.doi.org/10.1093/ibd/zaa010.090.

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Abstract Background Inflammatory bowel disease (IBD) pathogenesis includes the altered gut microbiota, environmental factors, human immune responses and genetic. Reduced bifidobacteria level is associated with IBD. Xyloglucan is a plant based prebiotic oligosaccharide. Bifidobacteria level is increased in the presence of xyloglucan. In this article we aim to share the results of our cases; Ulcerative colitis (UC) patients treated by intracolonic single administration of Bifidobacterium animalis subsp. lactis and Xyloglucan combination. Methods Ten UC patients were evaluated; before and after i
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Kim, Jihyun F., Haeyoung Jeong, Dong Su Yu, et al. "Genome Sequence of the Probiotic Bacterium Bifidobacterium animalis subsp. lactis AD011." Journal of Bacteriology 191, no. 2 (2008): 678–79. http://dx.doi.org/10.1128/jb.01515-08.

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ABSTRACT Bifidobacterium animalis subsp. lactis is a probiotic bacterium that naturally inhabits the guts of most mammals, including humans. Here we report the complete genome sequence of B. animalis subsp. lactis AD011 that was isolated from an infant fecal sample. Biological functions encoded in a single circular chromosome of 1,933,695 bp, smallest among the completely sequenced bifidobacterial genomes, are suggestive of their probiotic functions, such as utilization of bifidogenic factors and a variety of glycosidic enzymes and biosynthesis of polysaccharides.
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Liang, Xi, Zhe Zhang, Xiaohong Zhou, et al. "Probiotics improved hyperlipidemia in mice induced by a high cholesterol diet via downregulating FXR." Food & Function 11, no. 11 (2020): 9903–11. http://dx.doi.org/10.1039/d0fo02255a.

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