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1

Froning, Karen J., Arlene Sereno, Flora Huang, and Stephen J. Demarest. "Generalizable design parameters for soluble T cell receptor-based T cell engagers." Journal for ImmunoTherapy of Cancer 10, no. 3 (2022): e004281. http://dx.doi.org/10.1136/jitc-2021-004281.

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While most biological and cellular immunotherapies recognize extracellular targets, T cell receptor (TCR) therapeutics are unique in their ability to recognize the much larger pool of intracellular antigens found on virus-infected or cancerous cells. Recombinant T cell receptor (rTCR)-based therapeutics are gaining momentum both preclinically and clinically highlighted by recent positive phase III human clinical trial results for a TCR/CD3 bifunctional protein in uveal melanoma. Unlike antibody-based T cell engagers whose molecular formats have been widely and extensively evaluated, little dat
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2

Somerville, Rosie J. "Bifunctional beginnings." Nature Reviews Chemistry 5, no. 8 (2021): 518–19. http://dx.doi.org/10.1038/s41570-021-00295-0.

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3

Dixon, Darren J. "Bifunctional catalysis." Beilstein Journal of Organic Chemistry 12 (May 25, 2016): 1079–80. http://dx.doi.org/10.3762/bjoc.12.102.

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4

Popov, K. I., N. V. Tsirul'nikova, and N. M. Dyatlova. "Bifunctional complexones." Russian Chemical Reviews 64, no. 10 (1995): 939–51. http://dx.doi.org/10.1070/rc1995v064n10abeh000186.

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5

Li, Cong Qi, Bo Yu, Cheng Wang, Yong Xi Li, and Yu Chen. "An Easy Route for the Preparation of Soluble High Molecular Weight Polymer Under Friedel-Crafts Conditions." Advanced Materials Research 887-888 (February 2014): 989–92. http://dx.doi.org/10.4028/www.scientific.net/amr.887-888.989.

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A facile synthetic method that would be applied to polycondensation reaction between monomer A with bifunctional hydroxyl groups and monomer B with bifunctional reactive hydrogen atoms under Friedel-Crafts conditions was described. This approach, which has the advantage of short reaction time, high yield and simple synthesis operation, opens a way to prepare soluble high molecular weight polymers by the polycondensation reaction between monomer A with bifunctional hydroxyl groups and monomer B with bifunctional reactive hydrogen atoms under Friedel-Crafts conditions.
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6

Luo, Jia, Jiaqi Liu, Xiaoyan Guo, Yuejiao Liu, Haibo Jin, and Daidi Fan. "Preparation, Characterisation, and Application of Bifunctional BaSO4 Sheets." Materials 13, no. 13 (2020): 2903. http://dx.doi.org/10.3390/ma13132903.

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Barium sulfate (BaSO4) is a material with high reflectance for preparing bifunctional sheets used in dry reagent chemical tests. In this study, bifunctional BaSO4 sheets with scattering power and high reflectance were prepared with BaSO4 microspheres sized 1.3~1.8 μm and cellulose acetate (CA). Factors such as the BaSO4 morphology, CA dosage, mixing time, surfactant, solid content and wet sheet thickness were investigated. Scanning electron microscopy (SEM), a dynamic contact angle test, light reflection detector and light reflection densitometer were employed to characterize the structure and
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7

Mathialagan, Kowsalya, Saranya T, Ammu Surendran, Ditty Dixon, Nishanthi S.T., and Aiswarya Bhaskar. "(Digital Presentation) Development of Bifunctional Oxygen Electrocatalysts for Electrically Rechargeable Zinc-Air Batteries." ECS Meeting Abstracts MA2022-02, no. 4 (2022): 403. http://dx.doi.org/10.1149/ma2022-024403mtgabs.

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Zinc-air battery is a promising battery system as it possesses high theoretical energy density and is cost-effective3. The theoretical energy density of a Zinc-air battery is 1086 Wh kg-1, which is five times greater than that of lithium-ion batteries2. Moreover, zinc metal is one of the most abundant metals in the earth’s crust and is inexpensive. Rechargeable metal-air batteries operate based on two fundamental electrochemical reactions as Oxygen Reduction Reaction (ORR) during discharge and Oxygen Evolution Reaction (OER) during recharge processes, respectively3. Electrocatalytic activity o
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8

Carlier, Samuel, Walid Baaziz, Ovidiu Ersen, and Sophie Hermans. "Synergy between Sulfonic Functions and Ru Nanoparticles Supported on Activated Carbon for the Valorization of Cellulose into Sorbitol." Catalysts 13, no. 6 (2023): 963. http://dx.doi.org/10.3390/catal13060963.

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The production of sorbitol from biomass, and especially from its cellulosic component, has been studied as a sustainable method for producing platform molecules. Because it requires two steps, namely, hydrolysis and hydrogenation, bifunctional materials are required as catalysts for this transformation. This study reports a bifunctional catalyst composed of sulfonic functions grafted onto a carbon support for the hydrolysis step and RuO2 nanoparticles for the hydrogenation step. As sulfur can easily poison Ru, synthetic optimization is necessary to obtain an efficient bifunctional catalyst tha
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9

Zuo, Yuxin, Ying Yu, Haoqin Shi, Jiale Wang, Chuncheng Zuo, and Xiaowei Dong. "Inhibition of Hydrogen Evolution by a Bifunctional Membrane between Anode and Electrolyte of Aluminum–Air Battery." Membranes 12, no. 4 (2022): 407. http://dx.doi.org/10.3390/membranes12040407.

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The hydrogen evolution reaction of the anode is a severe barrier that limits the further commercial application of Al–air batteries. Therefore, this study introduces a bifunctional membrane for the inhibition of hydrogen evolution in Al–air batteries. The reference to Al2O3@PAN as “bifunctional” means that it has both hydrophobic and anti-corrosion functions. Al2O3 can effectively inhibit the migration of hydroxide ions, and PAN is an excellent hydrophobic material. The bifunctional membrane is placed between the aluminum anode and the electrolyte, which can prevent the invasion of excess wate
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10

Zhao, Chang-Xin, Jia-Ning Liu, Juan Wang, Ding Ren, Bo-Quan Li, and Qiang Zhang. "Recent advances of noble-metal-free bifunctional oxygen reduction and evolution electrocatalysts." Chemical Society Reviews 50, no. 13 (2021): 7745–78. http://dx.doi.org/10.1039/d1cs00135c.

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11

Arano, Yasushi. "Bifunctional Chelating Agent." Drug Delivery System 33, no. 1 (2018): 51–53. http://dx.doi.org/10.2745/dds.33.51.

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12

Shi, M., P. Toy, C. Kwong, R. Huang, and M. Zhang. "Bifunctional Polymeric Organocatalysts." Synfacts 2007, no. 5 (2007): 0549. http://dx.doi.org/10.1055/s-2007-968482.

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13

Kingwell, Katie. "Bifunctional therapeutic antibody." Nature Reviews Neurology 7, no. 7 (2011): 359. http://dx.doi.org/10.1038/nrneurol.2011.95.

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14

Ivanova, N. D., and S. V. Ivanov. "Bifunctional electrochemical systems." Russian Chemical Reviews 62, no. 10 (1993): 907–18. http://dx.doi.org/10.1070/rc1993v062n10abeh000053.

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15

Murzin, D. Yu. "Mesolevel Bifunctional Catalysis." Kinetics and Catalysis 61, no. 1 (2020): 80–92. http://dx.doi.org/10.1134/s0023158420010073.

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16

Yaroshchuk, O., and R. Kravchuk. "Bifunctional LCD Films." Molecular Crystals and Liquid Crystals 454, no. 1 (2006): 355/[757]—362/[764]. http://dx.doi.org/10.1080/15421400600656152.

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17

Steinhardt, Rachel, Stanley C. Hiew, Hemakesh Mohapatra, et al. "Cooperative CO2Absorption Isotherms from a Bifunctional Guanidine and Bifunctional Alcohol." ACS Central Science 3, no. 12 (2017): 1271–75. http://dx.doi.org/10.1021/acscentsci.7b00418.

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18

Li, Yanqiang, Ming Cui, Zehao Yin, Siru Chen, and Tingli Ma. "Metal–organic framework based bifunctional oxygen electrocatalysts for rechargeable zinc–air batteries: current progress and prospects." Chemical Science 11, no. 43 (2020): 11646–71. http://dx.doi.org/10.1039/d0sc04684a.

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The research progress of MOF-based bifunctional oxygen electrocatalysts for zinc–air batteries is reviewed and the main challenges and prospects for developing advanced MOF-based bifunctional electrocatalysts are proposed.
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19

Guo, Xiaoyan, Jiaqi Liu, Lixia Liu, Suohe Yang, Guangxiang He, and Haibo Jin. "Preparation, Characteristics, and Application of Bifunctional TiO2 Sheets." Materials 13, no. 7 (2020): 1615. http://dx.doi.org/10.3390/ma13071615.

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TiO2 is a high-reflectance material for preparing sheets during dry reagent chemical tests in detail. In this study, bifunctional TiO2 sheets with diffusive and reflective properties were prepared using TiO2 microspheres (particle size 2–3 µm) and cellulose acetate (CA). Factors such as the CA dosage, water content, mixing time, and the choice of surfactant were investigated. The structure and properties of the bifunctional TiO2 sheets were characterized by thermogravimetry and differential thermal analysis (TG-DAT), scanning electron microscopy (SEM), dynamic contact angle test and reflectanc
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20

Russell, Christopher K., Arunima Saxena, and Jeffrey T. T. Miller. "Influence of Bifunctional PtZn/SiO<sub>2</sub> and H-ZSM-5 Catalyst on the Rates and Selectivity of Propene Aromatization." Catalysis Research 03, no. 02 (2023): 1–17. http://dx.doi.org/10.21926/cr.2302018.

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Previous studies on the conversion of olefins to aromatics with bifunctional Ga- or Zn-ZSM-5 catalysts have concluded that benzene, toluene, and xylenes (BTX) yields are significantly higher than for ZSM-5 alone. These results were attributed to the higher aromatic dehydrogenation rate of Ga or Zn. In this study, a highly active, bifunctional PtZn/SiO&lt;sub&gt;2&lt;/sub&gt; (1.3 wt% Pt, 2.6 wt% Zn) with H-ZSM-5 (Si/Al = 40) catalyst is investigated for propene aromatization at 723 K and 823 K. At low to moderate propene conversions, in addition to BTX, small alkanes and olefins are produced.
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21

Ricardo, Carolynne, Piyush Kumar, and Leonard Wiebe. "Bifunctional Metal – Nitroimidazole Complexes for Hypoxia Theranosis in Cancer." Journal of Diagnostic Imaging in Therapy 2, no. 1 (2015): 103–58. http://dx.doi.org/10.17229/jdit.2015-0415-015.

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22

Jeong, Y. C., J. H. Kim, S. H. Kwon, et al. "Rational design of exfoliated 1T MoS2@CNT-based bifunctional separators for lithium sulfur batteries." Journal of Materials Chemistry A 5, no. 45 (2017): 23909–18. http://dx.doi.org/10.1039/c7ta08153g.

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1T exfoliated MoS<sub>2</sub>@CNT-based bifunctional separators in a tandem configuration delivered excellent electrochemical performance, and rational guidelines for preparing bifunctional separators for lithium sulfur batteries were suggested.
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23

Hou, Cheng, Jingxing Jiang, Yinwu Li, Zhihan Zhang, Cunyuan Zhao, and Zhuofeng Ke. "Unusual non-bifunctional mechanism for Co-PNP complex catalyzed transfer hydrogenation governed by the electronic configuration of metal center." Dalton Transactions 44, no. 37 (2015): 16573–85. http://dx.doi.org/10.1039/c5dt02163d.

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The unusual non-bifunctional mechanism for Co<sup>II</sup>-PNP catalyzed transfer hydrogenation is revealed to be governed by the electronic configuration of the metal center, which is different from traditional bifunctional catalysts.
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24

Wang, Xianfeng, Chunhong Li, Meihui Wang, Tao Zhao, and Wenyao Li. "Bifunctional Microcapsules with n-Octadecane/Thyme Oil Core and Polyurea Shell for High-Efficiency Thermal Energy Storage and Antibiosis." Polymers 12, no. 10 (2020): 2226. http://dx.doi.org/10.3390/polym12102226.

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A new kind of bifunctional microcapsule containing a n-octadecane (OD) and thyme oil (TO) core based on polyurea shell designed for thermal energy storage and antibiosis was prepared successfully through interfacial polymerization. The scanning electron microscopic investigations reveal that the obtained composite microcapsules present the regular spherical morphology and the transmission electron microscopic observations confirm the clear core–shell structure. Morphological and chemical structure analyses prove the successful synthesis of bifunctional microcapsules. Thermogravimetric analysis
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25

Sekar, Sankar, Ji-Seop Yun, Seoyeon Park, Deuk Young Kim, Youngmin Lee та Sejoon Lee. "Excellent Bifunctional Water Electrolysis Activities of α-MoO3/AC Nanocomposites". International Journal of Energy Research 2024 (25 січня 2024): 1–13. http://dx.doi.org/10.1155/2024/3167699.

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Electrocatalytic water splitting is a cost-effective and environment-friendly technique for producing oxygen and hydrogen through the oxygen/hydrogen evolution reaction (OER/HER). Developing the highly active and stable electrocatalyst, particularly for bifunctional water electrolysis (i.e., both OER and HER), is still a formidable challenge. Herein, we demonstrated the enhanced bifunctional water splitting activities by utilizing the molybdenum trioxide-anchored activated carbon (MoO3/AC) nanocomposites. The MoO3/AC samples were fabricated by the ultrasonication method using sol-gel synthesiz
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26

Polivanova, A. G., I. N. Solovieva, D. O. Botev, D. Y. Yuriev, A. N. Mylnikova, and M. S. Oshchepkov. "Bifunctional gallium cation chelators." Fine Chemical Technologies 17, no. 2 (2022): 107–30. http://dx.doi.org/10.32362/2410-6593-2022-17-2-107-130.

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Objectives. The chemistry of 67Ga and 68Ga radionuclides plays a key role in nuclear medicine for applications in radiopharmaceuticals, in particular, in noninvasive in vivo molecular imaging techniques. The use of radiometals for labeling biomolecules typically requires the use of bifunctional chelators, which contain a functional group for covalent bonding with the targeting vector in addition to the polydentate fragment coordinating the metal. The aim of the present review article is to analyze the currently accumulated experimental material on the development and application of bifunctiona
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27

WEI, GUANG-TAO, CHAO-HAI WEI, FENG-MEI HE, and CHAO-FEI WU. "A NOVEL CATALYST FOR REDUCTIVE DECHLORINATION OF CHLOROBENZENE IN SUBCRITICAL WATER: BIFUNCTIONAL Fe/ZrO2." Surface Review and Letters 16, no. 04 (2009): 617–21. http://dx.doi.org/10.1142/s0218625x09013050.

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Bifunctional Fe / ZrO 2 was prepared by mechanical mixing method, and its bifunctional effect on reductive dechlorination of chlorobenzene in subcritical water was studied. Dechlorination efficiency increased with increasing iron content in catalyst and catalyst amount. Dechlorination efficiency slowed when the iron content in catalyst reached 30%; bifunctional catalyst of Fe / ZrO 2 was more efficient in dechlorination of chlorobenzene than Fe alone. Catalyst of Fe (30%)/ ZrO 2 was characterized by means of X-ray diffraction (XRD), H 2 temperature programmed desorption ( H 2-TPD), and N 2 ads
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28

Zhang, Tian, Bikun Zhang, Qiong Peng, Jian Zhou, and Zhimei Sun. "Mo2B2 MBene-supported single-atom catalysts as bifunctional HER/OER and OER/ORR electrocatalysts." Journal of Materials Chemistry A 9, no. 1 (2021): 433–41. http://dx.doi.org/10.1039/d0ta08630d.

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29

Chen, Ming, and Jiaming Liu. "1,3-Bifunctional Nucleophilic Allylation Reagents: Preparative Methods and Synthetic Applications." Synthesis 53, no. 13 (2021): 2167–82. http://dx.doi.org/10.1055/a-1389-1438.

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Abstract1,3-Bifunctional nucleophilic allylation reagents play an important role in organic synthesis. In this short review, we summarize the methods for the preparation of 1,3-bifunctional reagents and their reactions with various electrophiles. Synthetic applications of these reagents in the context of complex molecule synthesis are also discussed.1 Introduction2 Reagent Synthesis2.1 Symmetrical Reagents2.2 Unsymmetrical Reagents2.2.1 Bis-silane and Silyl-stannane Reagents2.2.2 Bis-boron and Silyl-boron Reagents3 Synthetic Applications3.1 Allylation of Aldehydes3.2 Allylation of Ketones3.3 A
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30

Elsby, Matthew R., Scott Y. H. Kim, Stephan N. Steinmann, and R. Tom Baker. "Same ligand, three first-row metals: comparing M-amido bifunctional reactivity (Mn, Fe, Co)." Dalton Transactions 50, no. 41 (2021): 14542–46. http://dx.doi.org/10.1039/d1dt02637b.

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Three analogous M(SNS)2 complexes with bifunctional amido donors were used to compare reactivity across the base metals (M = Mn, Fe, Co). Experimental studies support DFT findings in which only the Mn complex can facilitate bifunctional H2 activation.
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31

Gao, Ming-Liang, Xiao-Man Cao, Yu-Yang Zhang, et al. "A bifunctional luminescent europium–organic framework for highly selective sensing of nitrobenzene and 4-aminophenol." RSC Advances 7, no. 71 (2017): 45029–33. http://dx.doi.org/10.1039/c7ra08885j.

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A bifunctional luminescent Eu-MOF can be applied as a highly selective and sensitive bifunctional luminescence sensor to detect NB and 4-AP through an energy competition mechanism with low detection limits of 5–70 ppm and 5–110 ppm, respectively.
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32

Staller, Max V., Ben J. Vincent, Meghan D. J. Bragdon, et al. "Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryo." Proceedings of the National Academy of Sciences 112, no. 3 (2015): 785–90. http://dx.doi.org/10.1073/pnas.1413877112.

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Hunchback (Hb) is a bifunctional transcription factor that activates and represses distinct enhancers. Here, we investigate the hypothesis that Hb can activate and repress the same enhancer. Computational models predicted that Hb bifunctionally regulates the even-skipped (eve) stripe 3+7 enhancer (eve3+7) in Drosophila blastoderm embryos. We measured and modeled eve expression at cellular resolution under multiple genetic perturbations and found that the eve3+7 enhancer could not explain endogenous eve stripe 7 behavior. Instead, we found that eve stripe 7 is controlled by two enhancers: the c
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33

Xu, Junwei, Ping Li, and Yubo Fan. "Preparation of Magnetic-Fluorescent Bifunctional Microrods as a Drug Delivery System via One-Step Electrospraying." Proceedings 78, no. 1 (2020): 44. http://dx.doi.org/10.3390/iecp2020-08646.

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Magnetic-fluorescent bifunctional drug delivery system which possesses magnetic targeting and fluorescent tracing capabilities effectively improves the delivery efficiency of drugs. With the in-depth study of the properties of non-spherical microparticles, it is found that the shape of the microparticles also plays a key role in drug delivery. Because of the unique shape, rod-like microparticles have exhibited great drug molecule metabolic dynamics and excellent anti-tumor effects during the process of treatment. In this study, Fe3O4/NaYF4:Eu3+/PLGA magnetic-fluorescent bifunctional microrods
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34

Zhou, Xiao-Fei, Wei Cheng, and Richard G. Compton. "Nano-impacts of bifunctional organic nanoparticles." Nanoscale 6, no. 12 (2014): 6873–78. http://dx.doi.org/10.1039/c4nr01943a.

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The synthesis and characterization of Oil Blue Dye nanoparticles is reported along with their use for nano-impacts experiments in aqueous solution to quantify the size of bifunctional organic nanoparticles by both direct reduction and oxidation routes of individual bifunctional organic nanoparticles.
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35

Ren, Xiaochen, Chunyan He, Yingle Feng, et al. "Novel ferrocene-based bifunctional amine–thioureas for asymmetric Michael addition of acetylacetone to nitroolefins." Organic & Biomolecular Chemistry 13, no. 17 (2015): 5054–60. http://dx.doi.org/10.1039/c5ob00298b.

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An efficient method was developed to synthesize the ferrocene-based bifunctional amine–thioureas bearing multiple hydrogen-bonding donors. Asymmetric Michael addition of acetylacetone to nitroolefins catalyzed by these novel bifunctional catalysts affords the Michael adducts in high yield and moderate to excellent enantioselectivities.
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36

Febriansyar, Rosyad Adrian, Teguh Riyanto, I. Istadi, Didi D. Anggoro, and Bunjerd Jongsomjit. "Bifunctional CaCO3/HY Catalyst in the Simultaneous Cracking-Deoxygenation of Palm Oil to Diesel-Range Hydrocarbons." Indonesian Journal of Science and Technology 8, no. 2 (2022): 281–306. http://dx.doi.org/10.17509/ijost.v8i2.55494.

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Palm oil is a promising raw material for biofuel production using the simultaneous catalytic mechanism of the bifunctional cracking-deoxygenation reactions. Through the cracking-deoxygenation process, the chains of palmitic acid and oleic acid in the palm oil were converted to diesel-range hydrocarbons. The combination effects of CaCO3 and HY zeolite enhanced the bifunctional catalytic cracking-deoxygenation of palm oil into biofuel, because of the increasing acid and basic sites in the catalysts due to the synergistic roles of CaCO3 and HY. The introduction of CaCO3 on HY zeolite generated bo
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37

Ikariya, Takao, and Yoshihito Kayaki. "Hydrogenation of carboxylic acid derivatives with bifunctional ruthenium catalysts." Pure and Applied Chemistry 86, no. 6 (2014): 933–43. http://dx.doi.org/10.1515/pac-2014-0103.

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AbstractThis paper focuses on recent advances in the chemistry of bifunctional Ru catalysts with chelate protic amine ligands effective for hydrogenation of polar carbonyl compounds. The rational design of the cooperating amine ligand that adjusts the balance of the electronic factors on the M/NH units in the bifunctional catalysts is crucial to exploit the characteristic catalytic performance with a wide scope and high practicability. These bifunctional molecular catalysts offer a great opportunity to develop new fundamental processes for the straightforward hydrogenation of carboxylic acid d
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38

Xue, Hansong, Choon-Hong Tan, and Ming Wah Wong. "Guanidine-catalyzed asymmetric Strecker reaction: modes of activation and origin of stereoselectivity." Canadian Journal of Chemistry 94, no. 12 (2016): 1099–108. http://dx.doi.org/10.1139/cjc-2016-0307.

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Density functional theory calculations were employed to study the catalytic mechanism, modes of activation, and origin of enantioselectivity of guanidine-catalyzed asymmetric Strecker reaction of N-benzhydryl imine with hydrogen cyanide. Two types of bifunctional activation mode were identified, namely conventional bifunctional Brønsted acid activation and unconventional bifunctional Brønsted–Lewis acid activation. The lowest-energy transition states correspond to the conventional bifunctional mode of activation. The calculated enantiomeric excess, based on eight lowest-energy C–C bond forming
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39

Guo, Jianing, Tingting Li, Qiuli Wang, Ningyuan Zhang, Yuanhui Cheng, and Zhonghua Xiang. "Superior oxygen electrocatalysts derived from predesigned covalent organic polymers for zinc–air flow batteries." Nanoscale 11, no. 1 (2019): 211–18. http://dx.doi.org/10.1039/c8nr08330d.

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The in situ synthesis of a bifunctional electrocatalyst based on a predesigned covalent organic polymer was reported. Remarkably, the obtained catalyst affords a remarkable bifunctional electrocatalytic performance with a small potential gap between E<sub>1/2</sub> and E<sub>j=10</sub> of 0.650 V.
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40

Maharramova, L. G. "CONVERSION OF METHANOL INTO FORMALDEHYDE AND DIMETHOXYMETHANE ON BIFUNCTIONAL CATALYSTS." Chemical Problems 18, no. 1 (2020): 97–101. http://dx.doi.org/10.32737/2221-8688-2020-1-97-101.

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41

Ikariya, Takao, Shigeki Kuwata, and Yoshihito Kayaki. "Aerobic oxidation with bifunctional molecular catalysts." Pure and Applied Chemistry 82, no. 7 (2010): 1471–83. http://dx.doi.org/10.1351/pac-con-09-09-11.

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A new series of half-sandwich group 8 and 9 metal complexes bearing a metal/NH bifunctional moiety were synthesized from benzylic amines. The isolable Ir amide complexes serve as effective catalysts for aerobic oxidative transformation of secondary and primary alcohols into the corresponding ketones and esters under mild conditions. The aerobic oxidative kinetic resolution of racemic secondary alcohols with chiral bifunctional Ir catalysts was found to proceed smoothly under mild conditions with high selectivity. A novel imido-bridged dirhodium complex, which may be regarded as a dinuclear var
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42

Moran, T. M., O. Usuba, H. Kuzu, Y. Kuzu, J. Schulman, and C. A. Bona. "Inhibition of multicycle influenza virus replication by hybrid antibody-directed cytotoxic T lymphocyte lysis." Journal of Immunology 146, no. 1 (1991): 321–26. http://dx.doi.org/10.4049/jimmunol.146.1.321.

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Abstract Bifunctional antibodies with specificity for the TCR/CD3 complex as well as to a target cell-surface Ag can redirect CTL to lyse the target cell. We have produced a hybrid hybridoma, HHA6, which secretes bifunctional antibodies capable of redirecting CTL to lyse influenza virus-infected target cells. When added along with CTL to virus-infected cells, these antibodies very efficiently inhibit multicycle virus replication. Because hybrid hybridomas reassort H and L chains randomly we attempted to purify bifunctional antibody by using HPLC. The purification increased the potency of HHA6.
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43

Ni, Xiaoxia, Zhengyang Liu, Jintang Guo, and Genlin Zhang. "Development of Terminator–Promoter Bifunctional Elements for Application in Saccharomyces cerevisiae Pathway Engineering." International Journal of Molecular Sciences 24, no. 12 (2023): 9870. http://dx.doi.org/10.3390/ijms24129870.

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The construction of a genetic circuit requires the substitution and redesign of different promoters and terminators. The assembly efficiency of exogenous pathways will also decrease significantly when the number of regulatory elements and genes is increased. We speculated that a novel bifunctional element with promoter and terminator functions could be created via the fusion of a termination signal with a promoter sequence. In this study, the elements from a Saccharomyces cerevisiae promoter and terminator were employed to design a synthetic bifunctional element. The promoter strength of the s
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44

Wang, Guilin, Xiaoqin Feng, Rongrong Ren, Yuxin Wang, Jie Meng, and Jianfeng Jia. "Theoretical Study on ORR/OER Bifunctional Catalytic Activity of Axial Functionalized Iron Polyphthalocyanine." Molecules 29, no. 1 (2023): 210. http://dx.doi.org/10.3390/molecules29010210.

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Designing efficient ORR/OER bifunctional electrocatalysts is very significant for reducing energy consumption and environmental protection. Hence, we studied the ORR/OER bifunctional catalytic activity of iron polyphthalocyanine (FePPc) coordinated by a series of axial ligands which has different electronegative coordination atom (FePPc-L) (L = -CN, -SH, -SCH3, -SC2H5, -I, -Br, -NH2, -Cl, -OCH3, -OH, and -F) in alkaline medium by DFT calculations. Among all FePPc-L, FePPc-CN, FePPc-SH, FePPc-SCH3, and FePPc-SC2H5 exhibit excellent ORR/OER bifunctional catalytic activities. Their ORR/OER overpo
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Kitamura, Masato. "Donor-Acceptor Bifunctional Catalyst." Journal of Synthetic Organic Chemistry, Japan 76, no. 10 (2018): 1114–17. http://dx.doi.org/10.5059/yukigoseikyokaishi.76.1114.

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CHATAL, JEAN-FRANCOIS, ALAIN FAIVRE-CHAUVET, MANUEL BARDIES, PATRICK PELTIER, EMMANUEL GAUTHEROT, and JACQUES BARBET. "Bifunctional Antibodies for Radioimmunotherapy." Hybridoma 14, no. 2 (1995): 125–28. http://dx.doi.org/10.1089/hyb.1995.14.125.

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Højholt, Karen T., Peter N. R. Vennestrøm, Ramchandra Tiruvalam, and Pablo Beato. "Tight bifunctional hierarchical catalyst." Chemical Communications 47, no. 48 (2011): 12864. http://dx.doi.org/10.1039/c1cc15413c.

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Nag, Angshuman, Akshay Kumar, P. Prem Kiran, S. Chakraborty, G. Ravindra Kumar, and D. D. Sarma. "Optically Bifunctional Heterostructured Nanocrystals." Journal of Physical Chemistry C 112, no. 22 (2008): 8229–33. http://dx.doi.org/10.1021/jp800063f.

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Tius, Marcus A., Jorge Gomez-Galeno, and Javid H. Zaidi. "A bifunctional anthraquinone synthon." Tetrahedron Letters 29, no. 52 (1988): 6909–12. http://dx.doi.org/10.1016/s0040-4039(00)88472-5.

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Dong, Steven D., and Ronald Breslow. "Bifunctional cyclodextrin metalloenzyme mimics." Tetrahedron Letters 39, no. 51 (1998): 9343–46. http://dx.doi.org/10.1016/s0040-4039(98)02160-1.

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