Academic literature on the topic 'Bifurcation of artery'

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Journal articles on the topic "Bifurcation of artery"

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Kalinin, Roman E., Igor’ A. Suchkov, Aleksandr V. Karpov, and Ivan N. Shanayev. "Anatomic Variants and Features of Atherosclerotic Lesion of Coronary Artery Bifurcations." Nauka molodykh (Eruditio juvenium) 12, no. 1 (2024): 25–34. https://doi.org/10.23888/hmj202412125-34.

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INTRODUCTION: Atherosclerotic lesion of coronary arteries is the ultimate cause of the development of the coronary heart disease. The situation becomes more complicated with the involvement of bifurcations of the coronary arteries, since their endovascular correction presents a problem which has not been completely solved until the present moment. AIM: To clarify the anatomic variants of coronary artery bifurcations and features of their lesion in atherosclerosis. MATERIALS AND METHODS: The study included 342 patients with an acute coronary syndrome, 85 of them had bifurcation stenoses of coro
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Stapleton, Christopher J., Jay I. Kumar, Brian P. Walcott, et al. "The effect of basilar artery bifurcation angle on rates of initial occlusion, recanalization, and retreatment of basilar artery apex aneurysms following coil embolization." Interventional Neuroradiology 22, no. 4 (2016): 389–95. http://dx.doi.org/10.1177/1591019916633243.

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Background Arterial bifurcations are common locations for aneurysm development given the altered hemodynamic forces and shear stress variations present at these locations. Recent reports indicate that a wide basilar artery bifurcation angle is an independent predictor of aneurysm development, growth, and subsequent rupture. Methods To determine the effect of basilar artery bifurcation angle on rates of initial occlusion, recanalization, and retreatment of basilar artery apex aneurysms following coil embolization, the records of 46 patients with basilar artery apex aneurysms treated with endova
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Chen, Bo, Wengui Tao, Shifu Li, et al. "Medial Gap: A Structural Factor at the Arterial Bifurcation Aggravating Hemodynamic Insult." Journal of Neuropathology & Experimental Neurology 81, no. 4 (2022): 282–90. http://dx.doi.org/10.1093/jnen/nlac017.

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Abstract Previous studies have reported that intracranial aneurysms frequently occur adjacent to the medial gap. However, the role of the medial gap in aneurysm formation is controversial. We designed this study to explore the potential role of the medial gap in aneurysm formation. Widened artery bifurcations with or without medial gaps were microsurgically created and pathologically stained in the carotid arteries of 30 rats. Numerical artery bifurcation models were constructed, and bidirectional fluid-solid interaction analyses were performed. Animal experiments showed that the apexes of wid
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Lee, Oh-Hyun, Ji Woong Roh, Eui Im, et al. "Feasibility and Safety of the Left Distal Radial Approach in Percutaneous Coronary Intervention for Bifurcation Lesions." Journal of Clinical Medicine 10, no. 10 (2021): 2204. http://dx.doi.org/10.3390/jcm10102204.

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Recently, the left distal radial approach (DRA) for percutaneous coronary intervention (PCI) has been shown to be a feasible option, but there are limited data regarding the feasibility of performing bifurcation PCI via the left DRA. Therefore, this study aimed to describe our experience with the contemporary left DRA to perform PCI of bifurcation lesions. Between December 2017 and December 2019, we identified 106 patients treated with bifurcation PCI via the left DRA. We evaluated the success rate of PCI, access-site complications including major bleeding requiring surgery or transfusion, hem
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Molavi Zarandi, Marjan, Rosaire Mongrain, and Olivier F. Bertrand. "Determination of Flow Conditions in Coronary Bifurcation Lesions in the Context of the Medina Classification." Modelling and Simulation in Engineering 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/419087.

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Coronary artery bifurcation lesions are complex and several classifications are presented to describe them. Recently, the Medina classification has been proposed. This classification uses binary values for characterization of stenosis. Flow conditions according to Medina classification have not been described. In this paper, bifurcation lesions corresponding to anatomical Medina lesion classification are compared on the basis of flow and Wall Shear Stress (WSS). Computational models of healthy and stenosed coronary artery bifurcations ((1, 1, 1), (0, 1, 1) and (1, 0, 1)) with moderate and seve
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Ingebrigtsen, Tor, Michael K. Morgan, Ken Faulder, Linda Ingebrigtsen, Trygve Sparr, and Henrik Schirmer. "Bifurcation geometry and the presence of cerebral artery aneurysms." Journal of Neurosurgery 101, no. 1 (2004): 108–13. http://dx.doi.org/10.3171/jns.2004.101.1.0108.

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Object. The angles of arterial bifurcations are governed by principles of work minimization (optimality principle). This determines the relationship between the angle of a bifurcation and the radii of the vessels. Nevertheless, the model is predicated on an absence of significant communication between these branches. The circle of Willis changes this relationship because the vessels proximal to the ring of vessels have additional factors that determine work minimization compared with more distal branches. This must have an impact on understanding of the relationship between shear stress and an
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M Ayman, Fakhry, Nagib Sohiel, and Elabd A. "Kissing Balloons Angioplasty for Infra-genicular Lower Limb Critical Ischemia." Archives of Anatomy and Physiology 10, no. 1 (2025): 001–5. https://doi.org/10.17352/aap.000024.

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Background: This study aimed to analyze the technical aspects and follow-up findings regarding patients with critical limb ischemia who underwent the Kissing Balloon Technique (KBT). Methods: 20 patients (22 bifurcations) were enrolled in this retrospective analysis between September 2020 and February 2022. All patients were submitted to infrapopletial intervention for critical limb ischemia. The KBT is the primary treatment in 3 situations: for cases with > 70% stenosis of the main artery located less than 1 cm of the bifurcation, occlusion of one branch with greater than 50% stenosis of t
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Koutouzi, Giasemi, Marcus Pfister, Katharina Breininger, Mikael Hellström, Håkan Roos, and Mårten Falkenberg. "Iliac artery deformation during EVAR." Vascular 27, no. 5 (2019): 511–17. http://dx.doi.org/10.1177/1708538119840565.

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Objectives To quantify the deformation of the common iliac artery caused by stiff guide wires and delivery systems during abdominal endovascular aortic repair (EVAR). Methods Twenty-two patients treated with abdominal EVAR were included. The following three image data-sets were acquired for each patient: (1) a preoperative computed tomography angiography (CTA), (2) an intraoperative contrast-enhanced cone beam CT (CBCT) obtained after the main trunk of the bifurcated stent graft was released and both iliac limbs were engaged with stiff guide wires, and (3) the first postoperative CTA. These da
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Kalinin, R. E., I. A. Suchkov, A. V. Karpov, and I. N. Shanaev. "Bifurcation stenting in patients with acute coronary syndrome." Russian Journal of Cardiology and Cardiovascular Surgery 18, no. 4 (2025): 399. https://doi.org/10.17116/kardio202518041399.

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Objective. To analyze the immediate and long-term results of bifurcation stenting in patients with acute coronary syndrome. Material and methods. The study included 265 patients with bifurcation coronary lesions who admitted with acute coronary syndrome. In 16 patients (6%), two lateral arteries arose from the affected area of the main artery. Thus, 281 bifurcations were included in the study. Patients underwent one-stent bifurcation stenting (provisional without kissing balloon dilation and provisional with kissing balloon dilation) and, if indicated, two-stent techniques (TAP, Culotte and DK
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Corballis, Natasha H., Sophie Paddock, Tharusha Gunawardena, Ioannis Merinopoulos, Vassilios S. Vassiliou, and Simon C. Eccleshall. "Drug coated balloons for coronary artery bifurcation lesions: A systematic review and focused meta-analysis." PLOS ONE 16, no. 7 (2021): e0251986. http://dx.doi.org/10.1371/journal.pone.0251986.

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Objectives We sought to systematically review the evidence supporting the role of drug coated balloons (DCBs) in the treatment of coronary bifurcation lesions. Background DCBs are emerging as an attractive alternative treatment strategy for treating coronary bifurcations due to simplifying the approach and reducing rates of stent related complications. We systematically reviewed the evidence for DCB use in coronary bifurcations and conducted a focused meta-analysis on late lumen loss in the side branch comparing DCB and plain old balloon angioplasty (POBA). Methods This study was conducted in
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Dissertations / Theses on the topic "Bifurcation of artery"

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Gin, Ronald. "Numerical modelling of the carotid artery bifurcation with a mild stenosis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0021/MQ58037.pdf.

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Jones, Zachary Ramey. "THE EFFECT OF ARTERY BIFURCATION ANGLES ON FLUID FLOW AND WALL SHEAR STRESS IN THE MIDDLE CEREBRAL ARTERY." DigitalCommons@CalPoly, 2014. https://digitalcommons.calpoly.edu/theses/1311.

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Saccular aneurysms are the abnormal plastic deformation of veins and arteries that can lead to lethal thrombus genesis or internal hemorrhaging. Medication and surgery greatly reduce the mortality rates, but treatment is limited by predicting who will develop aneurysms. A common location for saccular aneurysm genesis is at the main middle cerebral artery (MCA) bifurcation. The main MCA bifurcation is comprised of the M1 MCA segment, parent artery, and two M2 segments, daughter arteries. Studies have found that the lateral angle (LA) ratio of the MCA bifurcation is correlated with aneurysm form
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Ghalichi, Farzan. "Pulsatile laminar and turbulent blood flow simulation in large stenosed arteries and stenosed carotid artery bifurcation." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0013/NQ36272.pdf.

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Baalen, Jacob Marinus van. "Noninvasive detection of lesions in the carotid artery bifurcation a comparison between direct and indirect techniques /." Assen [etc.] : Maastricht : Van Gorcum ; University Library, Maastricht University [Host], 1987. http://arno.unimaas.nl/show.cgi?fid=5355.

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Ohya, Masanobu. "Long-Term Outcomes After Stent Implantation for Left Main Coronary Artery (from the Multicenter Assessing Optimal Percutaneous Coronary Intervention for Left Main Coronary Artery Stenting Registry)." Kyoto University, 2018. http://hdl.handle.net/2433/235034.

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Molavi-Zarandi, Marjan. "Characterization of physiological flow in stenosed and stented coronary artery bifurcations." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=117096.

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Myocardial infarction (MI) is a severe form of heart disease caused by the blockage of coronary arteries. Percutaneous coronary angioplasty of coronary artery bifurcation is associated with complications. The Medina classification is used by physicians to categorize the bifurcation lesions. However, the Medina classification is an anatomical classification which does not discriminate the complex disease. For example, there are reported cases, which are still unexplained, implying that there is anatomically significant appearance of a coronary stenosis in bifurcation disease detected by coronar
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Augst, Alexander David. "Haemodynamics in human carotid artery bifurcations : a combined CFD and 3D ultrasound study." Thesis, Imperial College London, 2003. http://hdl.handle.net/10044/1/11253.

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Reis, Samir Seme Arab. "Proposta de uma nova projeção angiográfica específica para a bifurcação da artéria coronária esquerda na era da intervenção percutânea do tronco coronário esquerdo." Universidade Federal de Uberlândia, 2016. https://repositorio.ufu.br/handle/123456789/18107.

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Introdução – Pouco se publicou na literatura médica a respeito de projeções angiográficas dedicadas às anatomias especiais. Neste cenário, propomos uma projeção angiográfica para a exposição da bifurcação do tronco da artéria coronária esquerda (TCE) quando o conjunto de projeções rotineiras previamente utilizadas foi ineficaz para exibir com clareza essa região. Pacientes e Métodos – 84 pacientes foram submetidos à projeção Lateral Direita (90-120°) associada a Cranial (30-40°). Estudo de reprodutibilidade, realizado com a participação de dois observadores independentes, julgou a eficácia da
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Yu, Xiaohong. "Hemodynamic analysis of blood flows in carotid bifurcations." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B3864700X.

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Yu, Xiaohong, and 于曉紅. "Hemodynamic analysis of blood flows in carotid bifurcations." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B3864700X.

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Books on the topic "Bifurcation of artery"

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Reuderink, Petrus Johannes. Analysis of the flow in a 3D distensible model of the carotid artery bifurcation. s.n.], 1991.

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Nicolaides, Andrew, Efthyvoulos Kyriacou, Constantinos S. Pattichis, and Kirk W. Beach. Ultrasound and Carotid Bifurcation Atherosclerosis. Springer London, Limited, 2016.

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Nicolaides, Andrew, Efthyvoulos Kyriacou, Constantinos S. Pattichis, and Kirk W. Beach. Ultrasound and Carotid Bifurcation Atherosclerosis. Springer, 2011.

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Kahn, S. Lowell. Balloon Anchor Techniques for Sheath, Guide Catheter, and Stent Advancement and to Facilitate Chronic Total Occlusion Traversal. Edited by S. Lowell Kahn, Bulent Arslan, and Abdulrahman Masrani. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199986071.003.0061.

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Advancement of a sheath or guide catheter into a small, diseased or angled branch vessel such as the superior mesenteric artery or renal artery can be difficult. Similarly, there are times when placement of a sheath up and over a sharply angulated aortic bifurcation can present a challenge. Obtaining a sheath position at or beyond a stenotic or occlusive lesion may be critical for delivering a stent, particularly with the inherent risk of dislodgment associated with balloon-expandable stents. The use of balloons as anchors has been described most commonly in the coronary vasculature, but it ca
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Khandelwal, Sarthak. Effect of Flow Diverting Stents on Intracranial Artery Bifurcations with a Focus on Bifurcating Vessels Diameter on Hemodynamics and Occlusion. GRIN Verlag GmbH, 2015.

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Book chapters on the topic "Bifurcation of artery"

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Legrand, Victor. "Classification of Coronary Artery Bifurcation Lesions." In Bifurcation Stenting. John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781444347005.ch1.

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Park, Seung-Jung, and Young-Hak Kim. "Stenting for Left Main Coronary Artery Bifurcation Lesions." In Bifurcation Stenting. John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781444347005.ch6.

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Bekelis, Kimon, Nicos Labropoulos, Maura Griffin, and Andrew Nicolaides. "Grading Internal Carotid Artery Stenosis." In Ultrasound and Carotid Bifurcation Atherosclerosis. Springer London, 2011. http://dx.doi.org/10.1007/978-1-84882-688-5_30.

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Amaya, Sergio E. Murillo, and Marios S. Pattichis. "Motion Estimation of Carotid Artery Plaques." In Ultrasound and Carotid Bifurcation Atherosclerosis. Springer London, 2011. http://dx.doi.org/10.1007/978-1-84882-688-5_21.

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Louvard, Yves, and Thierry Lefèvre. "Treatment of Coronary Artery Bifurcation Lesions." In Catheter-Based Cardiovascular Interventions. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-27676-7_31.

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Molinari, Filippo, and Jasjit S. Suri. "Automated Measurement of Carotid Artery Intima-Media Thickness." In Ultrasound and Carotid Bifurcation Atherosclerosis. Springer London, 2011. http://dx.doi.org/10.1007/978-1-84882-688-5_11.

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Drake, Charles G., Sydney J. Peerless, and Juha A. Hernesniemi. "Giant Basilar Artery Bifurcation Aneurysms: 137 Cases." In Surgery of Vertebrobasilar Aneurysms. Springer Vienna, 1996. http://dx.doi.org/10.1007/978-3-7091-9409-6_6.

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Abbott, Anne L. "Transcranial Doppler and Cerebrovascular Risk Stratification in Patients with Internal Carotid Artery Atherosclerosis." In Ultrasound and Carotid Bifurcation Atherosclerosis. Springer London, 2011. http://dx.doi.org/10.1007/978-1-84882-688-5_34.

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Cohen, José E., Hosni Abu Al-Hasan, Carlos Candanedo, Moatasim Shweiki, and Gustavo Rajz. "Internal Carotid Artery Bifurcation Aneurysm: Symptomatic Internal Carotid Artery Bifurcation Aneurysm in a Pediatric Patient Treated with Flow Diversion." In The Aneurysm Casebook. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-77827-3_121.

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Cohen, José E., Hosni Abu Al-Hasan, and Samuel Moscovici. "Middle Cerebral Artery Bifurcation Aneurysm: Saccular Aneurysm of the Middle Cerebral Artery Bifurcation Treated with a Flow Diverter Stent." In The Aneurysm Casebook. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-319-77827-3_95.

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Conference papers on the topic "Bifurcation of artery"

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Zarandi, Marjan Molavi, Rosaire Mongrain, Olivier F. Bertrand, and Ali Bonakdar. "Non-Newtonian Effects on Blood Flow Dynamics in Stented Coronary Artery Bifurcations." In ASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting collocated with 8th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-31187.

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From clinical practice, it is known that coronary artery bifurcations are regions where the flow is strongly perturbed, and is prone to the development of atherosclerotic lesions. Bifurcation lesions have always represented a major challenge for placement of stents for treatment of stenosis. Conventional bare metal stents are mostly used in clinical practice of bifurcation lesion treatments since there is no specific commercially available stent dedicated for treating bifurcations. Stent design is strongly influenced by the specific hemodynamic conditions in a given vessel. Therefore, in princ
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Bernad, S. I., A. I. Bosioc, A. F. Totorean, I. Petre, and E. S. Bernad. "Wall shear stress evolution in carotid artery bifurcation." In INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS (ICNAAM 2016). Author(s), 2017. http://dx.doi.org/10.1063/1.4992173.

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Zarandi, Marjan Molavi, Rosaire Mongrain, and Olivier F. Bertrand. "Modeling Drug Eluting Stents for Coronary Artery Bifurcation Considering Non-Newtonian Effects." In ASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting collocated with 8th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-31190.

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Drug Eluting Stents (DES) are commonly used for the treatment of stenotic arteries. Restenosis can be treated by delivering anti-thrombotic and anti-proliferative drugs to the arterial wall. The main mechanism of the drug eluting stent is to allow diffusion of the drug from the coating on the stent, into the arterial wall over a prolonged period of time. Investigation of blood flow hemodynamics and shear stress are of great importance in understanding the transport of drugs through the circulatory systems and predicting the performance of drug eluting stents. While drug eluting stent effective
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Berger, Stanley A., and Vitaliy L. Rayz. "Flow in the Stenotic Carotid Bifurcation." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32525.

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The carotid artery bifurcation is prone to the development of atherosclerotic plaques, and is a site where the consequences of this development can be severe. The most immediate effects are changes in lumenal cross-section, volumetric blood flow, and forces on the wall. The end result may be plaque rupture, possibly resulting in a stroke. Plaque development, and plaque rupture, are likely both strongly influenced by the changes of the shear stress, and possibly normal stress, at the artery wall [1]. Numerical simulations of the flow in the carotid bifurcation can elucidate the influence of the
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Choi, Gilwoo, Marie N. Dusch, Guanglei Xiong, Nan Xiao, Christopher P. Cheng, and Charles A. Taylor. "In Vivo Quantification of Human Coronary Artery Deformation From Cardiac-Gated Computed Tomography Data." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-205285.

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Despite significant advances in percutaneous coronary interventions (PCI), bifurcation lesions still remain technically challenging for treatment. In an attempt to treat bifurcation lesions, innovative interventional techniques such as T-stenting, V-stenting and crush stenting have been developed. However, stenting both main and branch vessels inherently involves geometrical constraint on the devices at the site of a branch junction. Moreover, dynamic cardiac motion may cause significant deformation of the coronary artery (Fig. 1) and hence may adversely impact the functionality as well as dur
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Kim, Soyoon, Kyoungchul Ro, and Hong Sun Ryou. "Numerical Investigation for the Effect of Blood Flow Rate and Asymmetric Bifurcation Angle on the Anterior Circulation Aneurysm Formation." In ASME-JSME-KSME 2011 Joint Fluids Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajk2011-19009.

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Most of aneurysms in the cranial cavity occur at the bifurcation of anterior circulation system. A cerebral aneurysm is easily ruptured, and it is fatal for most patients. Generally it is known that aneurysm occurs when arterial wall is deformed by high pressure or high wall shear stress (WSS). A blood flow pattern and the geometry and the blood vessel are important factors for aneurysm formation and the location. The transient interaction between blood flow and the arterial wall affects for simulating deformation of the blood vessel. Thus, numerical analysis is performed for various bifurcati
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Berger, Stanley A., and Jennifer S. Stroud. "Flow in the Atherosclerotic Carotid Artery." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-1924.

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Abstract The carotid artery bifurcation is vulnerable to the buildup of atherosclerotic plaque. This buildup may lead to vessel occlusion or to embolism or plaque rupture. Numerical simulations of blood flow in severely stenotic vessels, when considered in conjunction with experimental and in vivo data, can contribute to the understanding of plaque rupture. The Navier-Stokes equations are solved in their finite-volume formulation for carotid bifurcation geometries based on surgically removed specimens. Aspects of plaque morphology are isolated so that their effect on flow patterns and fluid me
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Momin, Marzia, Nusrat Ara, and M. Tarik Arafat. "Analysis of Blood Flow Patterns to Estimate Atherosclerosis Formation in the Left Carotid Artery by CFD Simulation." In ASME 2020 Fluids Engineering Division Summer Meeting collocated with the ASME 2020 Heat Transfer Summer Conference and the ASME 2020 18th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/fedsm2020-20052.

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Abstract The purpose of this computational fluid dynamics (CFD) study is to simulate left carotid artery models to evaluate the influence of hematocrit (Hct) level and angle of bifurcation on the formation of atherosclerosis. Bifurcation angle can vary from person to person based on sex, age or diseased condition which has an impact on hemo-dynamic parameters. From the anatomical study, it is seen that the carotid artery bifurcation is the preferential region for atherosclerosis formation. The combination of bifurcation, curvature and diameter change in this bifurcation region causes the blood
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Gallo, Diego, David A. Steinman, and Umberto Morbiducci. "Effect of Common Carotid Artery Inlet Length on Helical Flow at the Carotid Bifurcation: Influence on Exposure to Disturbed Shear." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80853.

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There is evidence that helical blood flow elicits atheroprotective fluid-wall interaction processes and regulates the transport of atherogenic particles at the luminal surface [1]. In particular, with reference to the carotid bifurcation it was also suggested that helical flow might play a key role in determining wall shear stress patterns [2]. Those findings suggest that a relationship could exist in the carotid bifurcation between exposure to disturbed shear and helical bulk flow patterns, an hypothesis that has been tested only in simplified models [3]. For this reason, in the present study
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Bressloff, N. W., J. Banks, and K. V. Bhaskar. "Parametric Geometry Definition and Analysis of the Human Carotid Artery Bifurcation." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-59124.

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Three-dimensional parametric computer aided design (CAD) geometry definitions of the human carotid artery bifurcation are presented for both Y-shaped and tuning-fork models. Drawing on methods largely developed in aerodynamic design, these parametric CAD geometries are deployed within a response surface methodology to systematically map the variation of spatially integrated mean shear stress with the angles of the internal carotid artery (ICA) and the external carotid artery (ECA). Although the absolute values of this shear stress metric agree in some regions of the design space, significant d
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