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Journal articles on the topic 'Bilateral multinodular goiter'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

LEVIN, RANDY. "Bilateral Horner's Syndrome Secondary to Multinodular Goiter." Annals of Internal Medicine 105, no. 4 (1986): 550. http://dx.doi.org/10.7326/0003-4819-105-4-550.

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2

Delbridge, Leigh. "Total Thyroidectomy for Bilateral Benign Multinodular Goiter." Archives of Surgery 134, no. 12 (1999): 1389. http://dx.doi.org/10.1001/archsurg.134.12.1389.

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3

Akdeniz, Didem Dereli, and Gürkan Avcı. "Total or less than total thyroidectomy for multinodular goiter long term follow-up." Medical Science and Discovery 8, no. 3 (2021): 181–86. http://dx.doi.org/10.36472/msd.v8i3.515.

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Objective: Multinodular goiter is a common surgical disease. There is no common consensus regarding the extent of thyroidectomy for multinodular goiter. This study aims to present personal experience on treating patients with multinodular goiter and to compare complication rates and results of total and partial thyroidectomy for multinodular goiter. Material and Method: Three hundred fifty patients underwent thyroidectomy for multinodular goiter between May 2003 and October 2010. All patients were diagnosed as multinodular goiter and were referred to surgery by one endocrinologist. All o

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4

Gapany, M. "Symptomatic benign multinodular goiter: Unilateral or bilateral thyroidectomy?" Yearbook of Otolaryngology-Head and Neck Surgery 2008 (January 2008): 184–85. http://dx.doi.org/10.1016/s1041-892x(08)79187-x.

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5

Olson, Sarah E., James Starling, and Herbert Chen. "Symptomatic benign multinodular goiter: Unilateral or bilateral thyroidectomy?" Surgery 142, no. 4 (2007): 458–62. http://dx.doi.org/10.1016/j.surg.2007.07.003.

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6

Fahey, T. J. "Symptomatic benign multinodular goiter: Unilateral or bilateral thyroidectomy?" Yearbook of Surgery 2008 (January 2008): 179–80. http://dx.doi.org/10.1016/s0090-3671(08)79067-0.

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7

Souza, John W., John T. Williams, Macram M. Ayoub, Matthew L. Jerles, and Martin L. Dalton. "Bilateral Recurrent Nerve Paralysis Associated with Multinodular Substernal Goiter: A Case Report." American Surgeon 65, no. 5 (1999): 456–59. http://dx.doi.org/10.1177/000313489906500516.

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Substernal goiter is an infrequent occurrence and is found in two to five per cent of all patients undergoing thyroid surgery. These lesions are well known to cause respiratory symptoms and alterations in phonation due to direct compression of airway structures. Infrequently, unilateral recurrent nerve palsy has been reported in patients with substernal goiter. We report a case of bilateral recurrent nerve palsy associated with multinodular substernal goiter in an 89-year-old female who presented in respiratory distress.

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8

Cohen-Kerem, Raanan, Pinhas Schachter, Maxim Sheinfeld, Elzbieta Baron, and Oded Cohen. "Multinodular Goiter: The Surgical Procedure of Choice." Otolaryngology–Head and Neck Surgery 122, no. 6 (2000): 848–50. http://dx.doi.org/10.1016/s0194-59980070012-x.

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Surgical management of multinodular goiter (MNG) poses an ongoing dilemma between radical resection with its associated complications and partial resection, which carries the risk of recurrence and increased morbidity and difficulty for rethyroidectomy. This study was designed to evaluate the recurrence rate and need for reoperation in a carefully selected population of MNG patients, after nontotal thyroidectomy. The study addressed a highly selected population of patients who were treated and thoroughly evaluated at one surgical department for several years. We analyzed the recurrence rate of

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9

Digonnet, Antoine, Esther Willemse, Cécile Dekeyser, Nicolas de Saint Aubain, Moreau Michel, and Guy Andry. "Surgical Management of Toxic Multinodular Goiter." World Journal of Endocrine Surgery 3, no. 2 (2011): 69–73. http://dx.doi.org/10.5005/jp-journals-10002-1060.

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ABSTRACT Management of toxic multinodular goiter (TMNG) is still debated. We report our current experience with thyroidectomy for toxic multinodular goiter at a tertiary center. A retrospective database of 141 patients who underwent surgery for TMNG disease from January 1985 to December 2008. During that period, six patients underwent subtotal thyroidectomy and 135 patients underwent near total thyroidectomy. Around 53 patients (38%) underwent surgery for recurrent disease after medical therapy; 88 patients (62%) had surgery as a primary treatment, the indications were large goiter size in 58

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10

KULAÇOGLU, HAKAN, CENAP DENER, IPEK ZIRAMAN, and NURI A. KAMA. "Thyroxine Prophylaxis after Bilateral Subtotal Thyroidectomy for Multinodular Goiter." Endocrine Journal 47, no. 3 (2000): 349–52. http://dx.doi.org/10.1507/endocrj.47.349.

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11

Grant, Clive S. "Invited Critique: Total Thyroidectomy for Bilateral Benign Multinodular Goiter." Archives of Surgery 134, no. 12 (1999): 1393. http://dx.doi.org/10.1001/archsurg.134.12.1393.

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12

Zavhorodnii, S. M., M. S. Gatia, М. А. Kubrak, and M. B. Danyliuk. "Surgical treatment of patients with nodular toxic goiter." Zaporozhye Medical Journal 23, no. 3 (2021): 370–74. http://dx.doi.org/10.14739/2310-1210.2021.3.229724.

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Nodular toxic goiter (NTG) accounts for 7.3 % to 10.0 % of the goiter population. There are difficulties in the preoperative differential diagnosis between NTG and other thyroid diseases. There is also controversy about the benefits of resection surgery over thyroidectomy in patients with NTG. The aim of the study: a comparative assessment of the diagnosis and treatment results of patients with NTG in the early and late postoperative periods after resection surgery and thyroidectomy. Materials and methods. The study enrolled 51 patients with NTG. The mean age of patients in the group was 51.7

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13

Mohammad, Benazeer H., Manju, Rahul Pusuluri, Srijan Pandey, Ashish Garg, and Rajat Saini. "Huge multinodular goiter with retrosternal extension, a challenge to both surgeon and anesthetist: a case report." International Journal of Research in Medical Sciences 13, no. 1 (2024): 421–23. https://doi.org/10.18203/2320-6012.ijrms20244148.

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Retrosternal goitre, defined as over 50% of the thyroid mass extending below the thoracic inlet, is a rare presentation of goitre. These cases are particularly observed among females in their 5th and 6th decades. Symptoms like breathlessness, facial flushing, and dysphagia, alongside complications like superior vena cava syndrome, increase morbidity. Surgery is the management of choice. While most cases are managed surgically via a cervical approach, some require thoracic intervention due to airway and neurovascular compression, including displacement of critical vessels like the subclavian an

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14

Tennyson, Heath Charles, and Joseph A. Brennan. "A Rare Etiology of Bilateral Vocal Fold Immobility: Multinodular Goiter." Otolaryngology–Head and Neck Surgery 131, no. 2 (2004): P297. http://dx.doi.org/10.1016/j.otohns.2004.06.652.

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15

Tennyson, Heath, Craig Fowler, and Joseph Brennan. "A Rare Etiology of Bilateral Vocal Fold Paresis: Multinodular Goiter." Otolaryngology–Head and Neck Surgery 134, no. 2 (2006): 340–42. http://dx.doi.org/10.1016/j.otohns.2004.12.009.

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16

Arican, Cigdem D., Tulin Ozturk, Muhammet Sait Sager, et al. "Incidental Papillary Microcarcinoma and Papillary Thyroid Carcinoma in Multinodular Goiter." Analytical Cellular Pathology 2023 (January 14, 2023): 1–7. http://dx.doi.org/10.1155/2023/2768344.

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Introduction. This study aimed to examine the incidence of incidental papillary microcarcinoma (PMC) and papillary thyroid carcinoma (PTC) in patients with benign multinodular goiter (MNG) and to compare their relationship with some prognostic factors from a new perspective. Methods. Bilateral total thyroidectomy (BTT) was used to evaluate the data of 716 patients who underwent a surgery for MNG. The prognostic data for these tumors and the relationship between patients with bilateral and multifocal tumors were evaluated using statistical tests. Results. Papillary carcinomas were detected in 2

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17

Li, Yujie, Yangjun Li, and Xiaodong Zhou. "Total Thyroidectomy versus Bilateral Subtotal Thyroidectomy for Bilateral Multinodular Nontoxic Goiter: A Meta-Analysis." ORL 78, no. 3 (2016): 167–75. http://dx.doi.org/10.1159/000444644.

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18

Yoldas, Tayfun, Ozer Makay, Gokhan Icoz, et al. "Should Subtotal Thyroidectomy Be Abandoned in Multinodular Goiter Patients From Endemic Regions Requiring Surgery?" International Surgery 100, no. 1 (2015): 9–14. http://dx.doi.org/10.9738/intsurg-d-13-00275.1.

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Abstract The most convenient surgical procedure for benign thyroid diseases is still controversial. The aim of this study is to determine the recurrence rate and risk factors for recurrence after different thyroidectomy procedures in multinodular goiter patients. Patients were separated into two groups according to the detection of a recurrent nodule or not after thyroidectomy. Of the 748 patients, 216 (29%) had recurrence, while 532 had no recurrent nodule. The difference between surgical procedures described as subtotal (ST), near total (NT) and total thyroidectomy (TT) was statistically sig

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19

Cholancheski, Risto, Natasha Tolevska, Ardit Qafjani, et al. "Evaluation of Total Thyroidectomy for Treatment of Benign Diseases of Thyroid Gland." Open Access Macedonian Journal of Medical Sciences 8, B (2020): 166–70. http://dx.doi.org/10.3889/oamjms.2020.3929.

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BACKGROUND: The controversy of using total thyroidectomy (TT) in treatment of benign thyroid diseases still remains controversial over the rates of complication, mostly recurrence nerve palsy and hypocalcemia, compared to non-total thyroidectomies. The latest reports in this field of research showed that that the number of complications of TT is decreasing as the skills of surgeons increase. AIM: In this study, we reviewed 209 cases of total thyroidectomies for benign thyroid diseases where such surgery was indicated. The results were evaluated whether they support the previous reports t

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20

Iriarte, María B., Eliana I. Morales, Mauricio Velásquez, Valeria Zúñiga, Luz F. Sua, and Liliana Fernández-Trujillo. "Giant Intrathoracic Goiter of Atypical Presentation: A Case Report." Clinical Pathology 13 (January 2020): 2632010X2091674. http://dx.doi.org/10.1177/2632010x20916741.

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Background: The term goiter is used to describe any abnormal growth of the thyroid gland, which can be diffuse or nodular, and can be associated with normal, diminished, or increased thyroid function. Multinodular goiter is a common disease whose prevalence increases at age 50. Clinical manifestations can be due to thyroid function impairment or related to size and location of the gland with compressive symptoms. Intrathoracic location is less frequent, can be mistaken with pulmonary lesions and usually implies a difficult surgical approach. Case presentation: A 66-year-old woman with a histor

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21

Adnan, Saeed Khan, Riaz Afridi, Abdullah, Arif Ahmed, and Mubashir Afridi. "Efficacy and safety of Total thyroidectomy in Multi Nodular Goitre management: a review of 172 cases." Khyber Journal Of Medical Sciences 14, no. 4 (2022): 208–11. https://doi.org/10.70520/kjms.v14i4.75.

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Background: Multinodular goiter is a common endocrine disorder worldwide. It presents mainly in the4th and 5th decade of life and is more common in women. Etiopathologically iodine deficiency isimplicated as most common factor. Objectives: Our study aimed to evaluate whether the outcomes of total thyroidectomy are safe andcan be considered as the optimal surgical approach for the treatment of Multinodular goiter.Materials and Methods: This was a retrospective analysis conducted on patients of Thyroid surgeriesfrom 1st January 2014 to 31stth December 2019 in ENT department Hayatabad Medical Com

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22

Maler, Neal, and Ellis R. Levin. "The Unusual Case of a Rapidly Enlarging Thyroid Gland in a Patient With Pendred Syndrome." Journal of the Endocrine Society 5, Supplement_1 (2021): A960. http://dx.doi.org/10.1210/jendso/bvab048.1962.

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Abstract Pendred syndrome is a genetic condition that is characterized by sensorineural hearing loss, abnormalities of the vestibular system, and goiter. In patients with Pendred syndrome, goiter tends to develop in late childhood or early adulthood and the literature details a progressive enlargement of goiter in these individuals. Here we report the case of a 26 year old female with Pendred syndrome and congenital deafness who presented with a rapidly enlarging thyroid gland over 1 week with associated symptoms of dysphagia, dyspnea, insomnia, and diaphoresis. Thyroid function tests at the t

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23

Yang, Weiping, Tanglei Shao, Jiazeng Ding, et al. "The Feasibility of Total or Near-Total Bilateral Thyroidectomy for the Treatment of Bilateral Multinodular Goiter." Journal of Investigative Surgery 22, no. 3 (2009): 195–200. http://dx.doi.org/10.1080/08941930902866279.

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24

Putri, Poppy Permata, Eva Decroli, Dinda Aprilia, Alexander Kam, Yanne Pradwi Efendi, and Syafril Syahbuddin. "AN UNUSUAL CASE PRESENTATION." Journal of the ASEAN Federation of Endocrine Societies 40, S1 (2025): 61. https://doi.org/10.15605/jafes.040.s1.102.

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INTRODUCTION/BACKGROUNDLung adenocarcinoma is a prevalent subtype of lung cancer known for its capacity to metastasize to various organs. In patients diagnosed with this cancer, thyroid nodules pose diagnostic challenges, as they may indicate metastasis or represent distinct conditions such as multinodular goiter or other thyroid malignancies. Notably, lung adenocarcinoma has a higher tendency to metastasize to the thyroid, with an incidence rate of 1–3%. CASEA 53-year-old female, undergoing chemotherapy for lung adenocarcinoma, presented to the Internal Medicine Clinic at RSUP M. Djamil Padan

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25

Mauriello, Claudio, Gianpaolo Marte, Alfonso Canfora, et al. "Bilateral benign multinodular goiter: What is the adequate surgical therapy? A review of literature." International Journal of Surgery 28 (April 2016): S7—S12. http://dx.doi.org/10.1016/j.ijsu.2015.12.041.

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26

Capellan, Maria Leonora, and Leo Tiu. "ODP590 Combined Orbital Irradiation and Systemic Steroids in the Management of Progressive Thyroid Eye Disease." Journal of the Endocrine Society 6, Supplement_1 (2022): A793. http://dx.doi.org/10.1210/jendso/bvac150.1640.

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Abstract We present a case of a 62-year-old female with Multinodular Toxic Goiter who later developed Grave's Ophthalmopathy. She had an elevated baseline TRAb with an orbital MRI that showed bilateral proptosis with enlarged bilateral medial and lateral recti and extraocular muscles of the superior complex. She was initially treated with oral steroids which led to resolution of her visual complaints. However, due to recurrence of an active ophthalmopathy, she was subsequently given pulsing corticosteroid therapy. This was followed by radiotherapy due to minimal improvement in double vision. A

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27

Oueslati, Ibtissem, Imen Sakka, Olfa Ismail, Ines Akrout, Adel Marghli, and Melika Chihaoui. "Tuberculosis of the Thyroid Gland Presented as a Rapid Enlargement of a Preexisting Goiter." Case Reports in Endocrinology 2018 (November 12, 2018): 1–4. http://dx.doi.org/10.1155/2018/4369531.

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Thyroid involvement with tuberculosis is an uncommon condition even in endemic countries. As its clinical presentation is not specific, diagnosis is often difficult and requires histopathological confirmation. Herein we report an observation of secondary tuberculosis of the thyroid gland in a woman with a type 2 diabetes mellitus and a primary hypothyroidism. She presented with a rapid enlargement of a preexisting goiter without compressive symptoms. The imaging exams showed a voluminous plunging multinodular thyroid gland and multiple bilateral lung nodules. Malignancy was suspected and the p

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28

Majid, M. A., and Md Ibrahim Siddique. "Major post-operative complications of thyroid surgery: Preventable or not?" Bangladesh Medical Research Council Bulletin 34, no. 3 (2009): 99–103. http://dx.doi.org/10.3329/bmrcb.v34i3.1973.

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Factors responsible for major complications following thyroid surgery in 598 patients were studied. Patients with non toxic multinodular goiter involving both lobes of thyroid constituted the maximum bulk subjected to thyroidectomy. The most frequent procedure was bilateral subtotal thyroidectomy. Reactionary hemorrhage occurred in 6 patients, all following bilateral procedures and among them 5 patients developed tension hematoma with respiratory obstruction despite the presence of a drain. Temporary vocal cord palsy was observed in 7 patients whereas one patient subjected to total thyroidecto

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T.V., Murali, Anuraj V .T., Kiran Vishnu Narayan, and Sajitha M. "Airway Fire During Tracheostomy." Bengal Journal of Otolaryngology and Head Neck Surgery 30, no. 3 (2023): 337–40. http://dx.doi.org/10.47210/bjohns.2022.v30i3.842.

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Introduction Airway fire is a life-threatening complication in the operation table which is preventable. We report an incident of airway fire that occurred during a tracheostomy and discuss what went wrong. Case report A 48-year-old gentleman with carcinoma tongue and multinodular goiter underwent modified radical neck dissection, hemithyroidectomy, tracheostomy, hemi glossectomy, and free radial forearm flap reconstruction. During tracheal hemostasis with cautery, a flame appeared, and airway burns resulted. It was extinguished in a few seconds with wet mops, but the resultant combustion inju

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Rahali, Anwar, Rahal Mssrouri, Hamid Mohamed, et al. "Intra-operative discovery of nonrecurrent inferior laryngeal nerve: a report of 3 cases including one of left nonrecurrent inferior laryngeal nerve and literature review." International Journal of Scientific Reports 8, no. 8 (2022): 236. http://dx.doi.org/10.18203/issn.2454-2156.intjscirep20221838.

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<p>The nonrecurrent inferior laryngeal nerve (NRILN), a rare variant in the course of the inferior laryngeal nerve, passes transversely into larynx directly arising from the vagus nerve that increases the risk of damage to the nerve during thyroid and parathyroid surgery. We discussed clinical significance of non-recurrent laryngeal nerve during cervicotomy. Its importance was demonstrated in three clinical cases as well as the related literature reviews. All patients underwent bilateral thyroidectomy for a multinodular goiter. Two patients had identification of the NRILN on the right si

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31

Wells, Gregg B., Todd M. Lasner, David M. Yousem, and Eric L. Zager. "Lhermitte-Duclos disease and Cowden's syndrome in an adolescent patient." Journal of Neurosurgery 81, no. 1 (1994): 133–36. http://dx.doi.org/10.3171/jns.1994.81.1.0133.

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✓ Recent reports of seven cases of Lhermitte-Duclos disease occurring in adult patients with Cowden's syndrome (multiple hamartoma syndrome) strongly suggest that Lhermitte-Duclos disease is one of the types of neoplasia that characterize this syndrome. A case of Lhermitte-Duclos disease is reported in a 16-year-old girl with craniomegaly, choroidal hamartoma, and conjunctival papilloma of the right eye, and a history of bilateral multinodular adenomatous goiter and cystic hygroma. These findings strongly suggest a diagnosis of Cowden's syndrome. Although the syndrome traditionally has been de

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32

Cansu, Guven Baris, B. Taskiran, T. Bakar, and B. P. Cengiz. "An unusual case in endocrinology practice: Suture granuloma." Endocrine Regulations 50, no. 3 (2016): 145–47. http://dx.doi.org/10.1515/enr-2016-0016.

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Abstract Objective. Suture granuloma, the rare complication of thyroidectomy, results from the use of nonabsorbable suture materials. Despite its typical ultrasound images and benign course, it carries utmost importance in the diff erential diagnosis of lymph nodes, recurrent nodules, and recurrence in the case of thyroid cancers. Subject and Results. Fifty four years old female patient, who underwent bilateral thyroidectomy in July 2010, was diagnosed with multinodular goiter and incidentally discovered micropapillary carcinoma (2 mm). Four years later, she was readmitted to hospital due to p

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33

Cherif, Yosra, Baha Zantour, Wafa Alaya, Olfa Berriche, Samia Younes, and Mohamed Habib Sfar. "Primary Hyperparathyroidism and Hyperthyroidism in a Patient with Myotonic Dystrophy: A Case Report and Review of the Literature." Case Reports in Endocrinology 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/735868.

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Various endocrine manifestations are commonly described in myotonic dystrophy (MD), including primary hypogonadism, diabetes mellitus, and thyroid and parathyroid dysfunction. We describe a 46-year-old woman with a family history of MD with her son. She was diagnosed with cardiac arrhythmia and required the implantation of a pacemaker. She was noted to have a bilateral cataract. She complained of muscle weakness, diffuse myalgia, and palpitation. The electromyography (EMG) showed myotonic discharges. Laboratory tests showed high serum calcium 2.83 mmol/L, serum phosphate 1.2 mmol/L, parathormo

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34

Haque, GHM Shahidul, Nahash Farid, and Sayed Sanaul Islam. "Incidence of Complications of Thyroid Surgery." Medicine Today 28, no. 2 (2017): 62–65. http://dx.doi.org/10.3329/medtoday.v28i2.32927.

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During the period of July 2009 to June 2012 the study was conducted on 200 cases of thyroid swelling in the Department of ENT and Head- Neck surgery, Rangpur Medical College Hospital, Rangpur. The age range of the study population was from 10 years to 75 years. Female to male ratio was 3.14:1. Diagnosis of all cases was established preoperatively by clinical examination, thyroid function tests, fine needle aspiration cytology (FNAC) and ultrasonogram (USG). Most of the patients were suffering from multinodular goiter. Maximum operations were done in the form of subtotal thyroidectomy followed

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35

Gurleyik, Emin, Sami Dogan, Omer Gunal, and Mevlut Pehlivan. "The Rare Coincidence: Nonrecurrent Laryngeal Nerve Pointed by a Zuckerkandl's Tubercle." Case Reports in Medicine 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/143049.

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The safety of thyroid operations mainly depends on complete anatomical knowledge. Anatomical and embryological variations of the inferior laryngeal nerve (ILN), of the thyroid gland itself and unusual relations between ILN and the gland threaten operation security are discussed. The patient with toxic multinodular goiter is treated with total thyroidectomy. During dissection of the right lobe, the right ILN which has nonrecurrent course arising directly from cervical vagus nerve is identified and fully isolated until its laryngeal entry. At the operation, we observe bilateral Zuckerkandl's tub

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Çeliker, Metin, Fatma Beyazal Çeliker, Arzu Turan, Mehmet Beyazal, and Hatice Beyazal Polat. "Submandibular Lateral Ectopic Thyroid Tissue: Ultrasonography, Computed Tomography, and Scintigraphic Findings." Case Reports in Otolaryngology 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/769604.

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Ectopic thyroid can be encountered anywhere between the base of tongue and pretracheal region. The most common form is euthyroid neck mass. Herein, we aimed to present the findings of a female case with ectopic thyroid tissue localized in the left submandibular region. A 44-year-old female patient, who underwent bilateral subtotal thyroidectomy four years ago with the diagnosis of multinodular goiter, was admitted to our hospital due to a mass localized in the left submandibular area that gradually increased in the last six months. Neck ultrasonography, contrast-enhanced computed tomography, a

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37

Williams, Vanessa, Hadoun Jabri, and Michael G. Jakoby. "Carney Complex With Endocrine Involvement Isolated to the Thyroid Gland." Journal of the Endocrine Society 5, Supplement_1 (2021): A992—A993. http://dx.doi.org/10.1210/jendso/bvab048.2030.

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Abstract Introduction: Carney complex is a rare autosomal dominant disorder characterized by pigmented lesions of skin and mucosae, endocrine neoplasms or overactivity, and myxomas of the heart, skin, and other organs. Most patients have at least two affected endocrine organs at time of diagnosis. We present a case of Carney complex with endocrine involvement limited to the thyroid gland. Case: A 48-year-old female was referred for evaluation of thyroid nodules incidentally discovered on imaging for submandibular salivary gland swelling. Ultrasound evaluation of the thyroid revealed numerous,

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Boeder, Schafer, Charles Choe, and Jimmy Mao. "PSAT324 Altered Mental Status, Hypercalcemia, and Atrial Fibrillation Induced by Post-Parathyroidectomy Thyroiditis." Journal of the Endocrine Society 6, Supplement_1 (2022): A823—A824. http://dx.doi.org/10.1210/jendso/bvac150.1704.

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Abstract Background Parathyroidectomy-induced thyroiditis is a rare but possibly underreported phenomenon. It has been reported in primary, secondary, and tertiary hyperparathyroidism, and typically presents with transient thyrotoxicosis in the days to weeks following surgery. Clinical Case A 66-year-old man with end stage renal disease complicated by tertiary hyperparathyroidism and no prior history of thyroid disease or cardiac dysrhythmia was admitted for parathyroidectomy. A multinodular goiter and four enlarged parathyroid glands were identified intraoperatively. With significant thyroid

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39

Guraya, Salman. "Total and Near-total Thyroidectomy is Better Than Subtotal Thyroidecomy for the Treatment of Bilateral Bening Multinodular Goiter; A Prospective Analysis." British Journal of Medicine and Medical Research 1, no. 1 (2011): 1–6. http://dx.doi.org/10.9734/bjmmr/2011/156.

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40

Castellano, Elena, Paolo Benso, Roberto Attanasio, et al. "Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study." International Journal of Endocrinology 2020 (February 22, 2020): 1–6. http://dx.doi.org/10.1155/2020/2182539.

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Background. Primary hyperparathyroidism (PHPT) and thyroid diseases are a frequent concomitant occurrence, but the surgical approach to associated disease is still debated. Methods. We retrospectively evaluated a series of PHPT patients focusing on thyroid disease and surgery. Results. Among 238 PHPT patients undergoing parathyroidectomy (PTX) between 2002 and 2017, 128 were affected also by a benign thyroid disease, namely, goiter in 118 (76 multinodular (MNG) and 42 uninodular (UNG)), autoimmune thyroiditis in 10, and hyperthyroidism in 21. Surgical approach was unilateral neck exploration (

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41

Roumpou, Afroditi, Argyro-Ioanna Ieronimaki, Aspasia Manta, et al. "A Novel Pathogenic Variant of DICER1 Gene in a Young Greek Patient with 2 Different Sex-Cord Ovarian Tumors and Multinodular Goiter." International Journal of Molecular Sciences 26, no. 5 (2025): 1990. https://doi.org/10.3390/ijms26051990.

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DICER1 syndrome (DICERs) represents a tumor predisposition genetic syndrome, inherited in an autosomal dominant manner. Germline loss-of-function variants of the DICER1 gene lead to impaired processing of microRNA, gene expression, and increased risk of tumorigenesis. Although pleuropulmonary blastoma (PPB) is the hallmark of the syndrome, multiple extrapulmonary malignant and non-malignant conditions have also been described, including multinodular goiter (MNG) and sex-cord stromal tumors. MNG is one of the most common components and is associated with an increased risk of thyroid carcinoma.

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Puntambekar, Shailesh, Abhishek Bhaumik, Suyog Bharambe, et al. "Endoscopic management of retrosternal goitres through cervical approach: a single centre experience." International Journal of Otorhinolaryngology and Head and Neck Surgery 8, no. 4 (2022): 363. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20220804.

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<h1><strong>Background:</strong> Retrosternal extension of thyroid poses a significant challenge due to its size and high vascularity. The objective of this study was to assess the outcomes of endoscopic approach via cervical approach for retrosternal thyroid removal.</h1><h1><strong>Methods:</strong> This was a hospital based retrospective cross-sectional study, conducted among<strong> 12 patients of goitres with retrosternal extension who fulfilled the inclusion criteria for endoscopic excision via cervical approach from January 2016 to Decembe

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Rico, Ferdinand, and John Lung. "Thyroid Embryonic Anomalies Involving the Medial and Lateral Anlagen: Two Surgical Case Reports." Case Reports in Surgery 2019 (December 5, 2019): 1–6. http://dx.doi.org/10.1155/2019/3174848.

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Introduction. An ectopic anomalous accessory thyroid is extremely rare. We present two related case reports. Case. A 43-year-old morbidly obese female presented with a palpable left thyroid mass. Initial impression after preoperative workup was a diffuse bilateral multinodular goiter with a left nodule suspicious for malignancy. She underwent a total thyroidectomy. On further palpation after initial excision, two masses on the left neck area were noted, dissected, and excised. In the second case, a 65-year-old female presented with a substernal exophytic mass displacing the trachea to the righ

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Barczyński, Marcin, Aleksander Konturek, Alicja Hubalewska-Dydejczyk, Filip Gołkowski, Stanisław Cichoń, and Wojciech Nowak. "Five-year Follow-up of a Randomized Clinical Trial of Total Thyroidectomy versus Dunhill Operation versus Bilateral Subtotal Thyroidectomy for Multinodular Nontoxic Goiter." World Journal of Surgery 34, no. 6 (2010): 1203–13. http://dx.doi.org/10.1007/s00268-010-0491-7.

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Barczyński, Marcin, Aleksander Konturek, Alicja Hubalewska-Dydejczyk, Filip Gołkowski, and Wojciech Nowak. "Ten-Year Follow-Up of a Randomized Clinical Trial of Total Thyroidectomy Versus Dunhill Operation Versus Bilateral Subtotal Thyroidectomy for Multinodular Non-toxic Goiter." World Journal of Surgery 42, no. 2 (2017): 384–92. http://dx.doi.org/10.1007/s00268-017-4230-1.

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Farook, Dr Mohammad Omar, Dr Mohammad Jamal Hussain, and Dr Kazi Shah Alam. "Subtotal Thyroidectomy Postoperative Complications with Unplanned Thyroid Surgery." SAS Journal of Medicine 9, no. 04 (2023): 289–92. http://dx.doi.org/10.36347/sasjm.2023.v09i04.011.

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Background: The surgical treatment for bilateral multinodular nontoxic goiter (BMNG) is still debatable. Avoiding RLN harm during thyroid surgery if the pathology is not identified. Reduce the incidence of hypoparathyroidism by reducing the rate of parathyroid gland damage during excision. Objective: To see the complications of subtotal thyroidectomy in random thyroid surgery. Materials and Methods: This was a prospective, observational study conducted in the Department of ENT & Head- Neck surgery, Rangamati Medical College, Rangamati for a period of 2 years from January 2019 and December

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Hassan, Iyad, Lina Hassan, Ibrahim Gamal, Mohamad Ibrahim, and Abdel Rahman Omer. "Abu Dhabi Neural Mapping (ADNM) during Minimally Invasive Thyroidectomy Enables the Early Identification of Non-Recurrent Laryngeal Nerve and Prevents Voice Dysfunction." Journal of Clinical Medicine 11, no. 19 (2022): 5677. http://dx.doi.org/10.3390/jcm11195677.

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The aim of this study was to evaluate the diagnostic accuracy of a neuromonitoring protocol—the Abu Dhabi Neural Mapping protocol (ADNM)—using a new device, Nim-Vital™, during minimally invasive thyroidectomy in the early identification of non-recurrent laryngeal nerve (n-RLN) problems and the preservation of its function. Method: Patients with thyroid disorders that required thyroid resection, who were admitted to the Department of Surgery at Burjeel Hospital, Abu Dhabi, between January and July 2022, were included in the study. The data were extracted from a prospective database and were ana

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Falco, O., S. Taras, P. Maninchedda, S. Cambule, and M. Atzori. "P435 THE IMPORTANCE OF CORRELATION BETWEEN HEART FAILURE AND THYROID: A CASE REPORT." European Heart Journal Supplements 25, Supplement_D (2023): D215. http://dx.doi.org/10.1093/eurheartjsupp/suad111.501.

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Abstract A 39–year–old African man was admitted to our department within a four days symptoms of short of breath, cough, tachycardia and lower limb edema. He also complained headache for about a month. He denied fever, chest pain and loss of consciousness. Clinical and family history were unremarkable. Blood tests showed moderate microcytic anemia ( Hb 9.6 g/dl, MCV 93.3 fL), hypoalbuminemia ( Albumin: 3.20 g/dl), elevated levels of LDH ( LDH: 246 U/L), mild C–reactive protein (CRP) and pro–Brain Natriuretic Peptide (pro–BNP) increase (CRP: 1.14 mg/dl); (PRO–BNP: 1133 pg/mL) and negative tropo

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Rifani, Rizqi, and Dyah Purnamasari. "MARINE-LENHART SYNDROME." Journal of the ASEAN Federation of Endocrine Societies 40, S1 (2025): 38–39. https://doi.org/10.15605/jafes.040.s1.061.

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INTRODUCTION/BACKGROUND Marine-Lenhart syndrome is a rare thyroid disorder characterized by the presence of Graves’ disease and autonomously functioning thyroid nodules. This dual pathology poses a diagnostic and therapeutic challenge as it combines features of autoimmune hyperthyroidism and toxic multinodular goiter. The prevalence is estimated to be 0.8–4.1% among patients with Graves’ disease. Patients with Marine-Lenhart Syndrome generally have lower remission rates with thionamide therapy, unlike typical Graves’ disease, and frequently require definitive treatment such as radioiodine abla

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Kusumaningtyas, Luki, Tri Juli Edi Tarigan, and Pradana Soewondo. "MALIGNANT STRUMA OVARII IN A PATIENT WITH GRAVES’ DISEASE." Journal of the ASEAN Federation of Endocrine Societies 40, S1 (2025): 62. https://doi.org/10.15605/jafes.040.s1.104.

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INTRODUCTION/BACKGROUNDMalignant struma ovarii (MSO) is a rare ovarian teratoma containing malignant thyroid tissue, accounting for <5% of all struma ovarii cases. Papillary carcinoma is the most common histological subtype, followed by follicular carcinoma. Diagnosis may be challenging, especially when coexisting with thyroid nodules or autoimmune thyroid diseases such as Graves’ disease, due to overlapping histologic and functional features. CASEA 58-year-old female with longstanding hyperthyroidism due to Graves’ disease presented with an abdominal mass measuring 15 × 10 × 9 cm. Laparoto

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