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Relevant bibliographies by topics / Bilayer formulation

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Academic literature on the topic 'Bilayer formulation'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Bilayer formulation"

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Pallavi, T., G. S. Sharma, B. Rama, L. Jyothi Rani, and B. Rajkamal. "Formulation and evaluation of floating bilayer tablets of epleronone." World Journal of Pharmaceutical Sciences 10, no. 04 (2022): 08–17. http://dx.doi.org/10.54037/wjps.2022.100402.

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Gastro retentive drug delivery systems have been widely used to prolong retention of dosage forms in stomach. Among the various approaches, the floating bilayer tablets formulation offers sustained drug release as well as prolonged gastric retention, along with the added advantage of liquid oral dosage form. The present study was an attempt to formulate and evaluate floating bilayer tablets of Epleronone by using various polymers like guar gum, ethyl cellulose, SSG, CCS. The prepared floating Bilayered tablets were evaluated for hardness, Weight variation, thickness, friability, drug content u

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Jangid, Vikash, Arindam Chatterjee, Saurabh Pandey, Vikash Agarwal, and Deeksha Sharma. "Formulation and Evaluation of Bi-Layer Tablet of Nebivolol and Nateglinide." Journal of Biomedical and Pharmaceutical Research 12, no. 3 (2023): 34–42. http://dx.doi.org/10.32553/jbpr.v12i3.993.

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In the present work, the Bilayered matrix type tablet were prepared by direct and wet granulation technique, in which immediate release layer ( by direct compression) contains Nebivolol and extended release layer (by wet granulation) contains Nateglinide. All the developed bilayer tablets were evaluated for weight variation, friability, thickness and hardness. The percent deviation from the average weight, friability, thickness and hardness was found to be within the prescribed official limits. Release profile of Nebivolol from formulations indicate that lower MCC (Formulations CF1 and CF3) an

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Gandhi, Kunjan, Sunil Kumar Shah, C. K. Tyagi, Prabhakar Budholiya, and Harish Pandey. "Formulation, Development and Evaluation of Uncoated Bilayer Tablet of Anti-Hypertensive Agents." Journal of Drug Delivery and Therapeutics 10, no. 4-s (2020): 100–107. http://dx.doi.org/10.22270/jddt.v10i4-s.4229.

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The present research work was carried out to Formulate and evaluation of bilayer tablet dosage form for the treatment of Hypertension.The objective of this study to compare the specific characteristics of Metoprolol [beta selective (cardio selective) adrenoreceptor blocking agent] and Hydrochlorothiazide (Thiazide Diuretics]) in order to design stable formulation. It can be concluded that bilayer tablet were successfully formulated to achieve immediate release of Hydrochlorothiazide (HCTZ) and tailored release of Metoprolol (MPL)by using Dual Release Drug Absorption System(DUREDAS technology).

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Saha, Shreya, Mithun Bhowmick, and Rimpa Goswami. "Bilayer Tablet: Novel Technology Use in Extended Release Drug Delivery System." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 962–65. http://dx.doi.org/10.22270/jddt.v9i3-s.2877.

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Bilayer tablet is a successful technology of controlled release formulation or extended release formulation to provide successful drug delivery. The name of this development is clear that the tablets have been consisting of two layers, these are immediate release layer (IR) and another is extended release layer (ER). In this era it is very useful in many developing countries as a combination therapy for various disease treatment purposes. Bilayer tablet are needs to separate incompatible active pharmaceutical ingredients (API) by physical separation. In this formulation IR and ER both layers a

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K, Kulkarni, and Deokar G. "From Challenges to Advancement for Bilayer Tablet Technology as Drug Delivery System." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 1676–82. https://doi.org/10.25258/ijddt.14.4.64.

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Bilayer tablet technology is in focus because it advantageous for combination therapy, for combining two different release profile and it gives patent novelty to existing dosage. Hence its advantages, challenges and applications need to be discuss. The objective of preparing a review article on bilayer tablets is multifaceted, aiming to cover challenges at formulation development to scaleup and opportunity for new product development by integrating it bilayer tablet technology with other formulation technology. With reference to all the electronic data it was found that bilayer tablets face ma

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Reddy, K. Srinivasa, D. Vinay Kumar, CH Lakshmi Bharath, and P. Sri Ramya Madhuri. "FORMULATION AND EVALUATION OF SUMATRIPTAN SUCCINATE AND NAPROXEN SODIUM GASTRORETENTIVE (FLOATING) BILAYERED TABLETS." INDIAN DRUGS 57, no. 10 (2021): 30–41. http://dx.doi.org/10.53879/id.57.10.12196.

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The main aim of the present work was to formulate and evaluate sumatriptan succinate and naproxen sodium gastro retentive(floating) bilayered tablets. Floating bilayer tablets were formulated using direct compression method, it consist of two layers i.e IR layer containing Naproxen and floating CR layer containing sumatriptan. IR2 layer containing 2% concentration of Cross Povidone was found to be optimum and released 99.23% of naproxen in 45min. The optimized floating CR8 layer containing HPMC K 100M in 46% concentration showed 81.21% of drug release at the end of 12h. Among all formulations,

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Jamshiya.E*, and Anju.P. "FORMULATION, EVALUATION AND OPTIMIZATION OF FLOATING MATRIX TABLETS OF CARVEDILOL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 02 (2018): 1146–58. https://doi.org/10.5281/zenodo.1188894.

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Bilayer floating tablets were prepared by direct compression using HPMC K100M and Ethyl cellulose as the release controlling polymers and sodium bicarbonate as a gas generating agent. The optimum concentrations of the above ingredients were determined under experimental conditions and on the basis of trial batches of the tablets. In the present study bilayer tablet was prepared manually using single station punching machine. Accurately weighed 150mg of sustained release layer powder mixture was fed manually into die cavity. Sustained release layer was compressed at mild compression force (2-3

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Subhash Tarate, Mr Vivek, and Dr Jagdishchandra Pati. "A Study on Bilayer Tablets for the Anti-Allergic Drug." Journal of Drug Discovery and Therapeutics 11, no. 2 (2023): 29–39. http://dx.doi.org/10.32553/jddt.v11i2.462.

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The bilayer tablet formulations used for each individual layer should be compressible (i.e., the capacity of a material to undergo a reduction in volume as a result of an applied pressure) and compactable (i.e., the capacity of a powder to be transformed into tablets with strength during densification) on their own, i.e., they should show satisfactory reduction in volume and form mechanically sound and coherent solid bodies. A bigger contact area exists between the layers as a result of the increased surface roughness, which improves interlayer adhesion. Bilayer tablet characterisation in earl

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Yunus, Attar Arshan. "Formulation and Evaluation of Bilayer of Omeprazole Sustained release action." International Journal of Research Publication and Reviews 6, no. 5 (2025): 16491–98. https://doi.org/10.55248/gengpi.6.0525.19106.

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Arti, Parmar* Akanksha jagwani Toshiba Khanam Narendra Gehalot Vikas Jain. "COMPREHENSIVE REVIEW ON FORMULATION AND MANUFACTURING TECHNIQUES OF BILAYER TABLETS." International Journal in Pharmaceutical Sciences 2, no. 8 (2024): 3117–21. https://doi.org/10.5281/zenodo.13316959.

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Bilayer tablets are an inventive and adaptable drug delivery device because they have two layers, each with a unique drug release profile. This review summarises the development, manufacturing processes, formulation strategies, and pharmaceutical uses of bilayer tablets. Carefully choosing formulation ingredients is essential to the effectiveness of these tablets, taking into account medication compatibility as well as the effects of formulation variables on stability and bioavailability. A range of manufacturing approaches are examined, emphasising their scalability and appropriateness for ce

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Books on the topic "Bilayer formulation"

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Formulation and Evaluation of Antiviral Bilayered Floating Tablets. Independently Published, 2020.

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Book chapters on the topic "Bilayer formulation"

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Shamblin, Sheri L. "Controlled Release Using Bilayer Osmotic Tablet Technology: Reducing Theory to Practice." In Oral Controlled Release Formulation Design and Drug Delivery. John Wiley & Sons, Inc., 2010. http://dx.doi.org/10.1002/9780470640487.ch9.

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Öztürk Öncel, M. Özgen, Bora Garipcan, and Fatih Inci. "Biomedical Applications: Liposomes and Supported Lipid Bilayers for Diagnostics, Theranostics, Imaging, Vaccine Formulation, and Tissue Engineering." In Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-11596-8_8.

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Bhatjire, Gitanjali S., Priyanka P. Thore, Vandana V. Shirsath, and Vaishali Naphade. "Advances in liposomal drug delivery: Formulation and optimization." In Targeted Therapies and Drug Delivery Systems: A Multidisciplinary Perspective. Deep Science Publishing, 2025. https://doi.org/10.70593/978-93-7185-674-4_1.

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This abstract discusses advances in the field of liposome research, focusing on their nano-details, functionalization, and commercialization. Liposomes, which are bio-degradable and bio-compatible phospholipid bilayer vesicles, are favored carriers for conveying both hydrophobic and hydrophilic bioactives. Clinically, liposomal medicate conveyance frameworks are utilized to treat cancer, contagious contaminations, and viral contaminations, with many advanced clinical trials. The development of liposomes has evolved to meet clinical and industrial demands, including ligand acquisition, long cir

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Sharma, Rachana, and Uma Sharma. "LIPID BASED VESICLES: FORMULATION AND LOADING OF ANTIHYPERTENSIVE DRUG ATENOLOL." In Futuristic Trends in Chemical Material Sciences & Nano Technology Volume 3 Book 1. Iterative International Publishers, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bdcs1ch15.

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The term ‘vesicles’ is used to define circular or ellipsoidal single or multicompartment, closed double layered structures irrespective of their chemical structure. Liposomes are microscopic, tiny synthetic vesicles of sphere-shape that can be formed from cholesterol and natural phospholipids in water as solvent causing closed bilayer structures to form. In present work, lipid-based vesicles were synthesized (by soy lecithin and cholesterol) and loaded with antihypertensive model drug Atenolol by using Rotatory-evaporator. The synthesized liposomes were further evaluated by Fourier Transform I

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Schué, F., R. Sagnes, L. Giral, and C. Montiginoul. "A New Positive Optical Resist for Bilayer Resist Systems." In Silicon-Containing Polymers. Royal Society of Chemistry, 1995. http://dx.doi.org/10.1039/9781837672448-00164.

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Thi s paper describes a positive resist formulation [PSi] containing silylated polystyrene polymer, made photosensitive at 436 nm wavelength, by means of an onium salt sensitizer and a dye photosensitizer. This resist system is highly resistant to etching in an oxygen plasma and could be integrated into a bilayer resist process as a thin imaging layer coated on a thick hard baked novolac resist layer. Its behaviour as a photosensitive resist at ’A = 436 nm and as a positive deep uv resist at ’A = 257 nm have been evaluated. The schematic function of the resist and its lithographic properties a

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Shabanpour, Sakineh. "Phytosome: A Novel Drug Delivery Approach in Herbal Medicine." In Dosage Forms - Emerging Trends and Prospective Drug-Delivery Systems [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1005766.

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Phytomedicine is known widely in novel drug delivery systems due to its herbal properties. Extracting the effective substance of plants and targeting the drug to the desired site is a challenging task. Many biologically active constituents are water soluble, which reduce their absorption and thus their bioavailability. Phytosome technology has solved this problem. Phytosomes, due to amphiphilic properties, can effectively absorb from a hydrophilic environment to a lipophilic environment such as a cell membrane and finally reach the blood circulation system. The increase in bioavailability also

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Parashar, Tarun, and Soniya Rani. "Formulation and In –Vitro Evaluation of Bilayer Tablet of Atenolol for Biphasic Drug Release: Experimental Investigation." In Challenges and Advances in Pharmaceutical Research Vol. 2. Book Publisher International (a part of SCIENCEDOMAIN International), 2022. http://dx.doi.org/10.9734/bpi/capr/v2/15687d.

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Patel, Vaibhavi, and Pranav Y. Dave. "Liposomal Technology in Drug Formulations: Enhancing Therapeutic Efficacy and Safety." In Latest Research on Drug Formulation Design [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1007868.

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Liposomes are vesicular structures made of lipid bilayers that naturally develop when phospholipids scatter in water. These small vesicles included an aqueous core within a membrane made of lipid bilayers. Novel Drug Delivery Systems (NDDS) are intended to release medications at a controlled rate dependent on the body’s needs during therapy while targeting specific locations of action. Liposomes, which are spherical structures made up of phospholipid bilayers, have gained popularity in therapeutic formulations due to their ability to encapsulate both hydrophilic and hydrophobic medicines. This

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Yaghmur, Anan, Jesper Østergaard, Susan Larsen, Henrik Jensen, Claus Larsen, and Michael Rappolt. "Drug Formulations Based on Self-Assembled Liquid Crystalline Nanostructures." In Liposomes, Lipid Bilayers and Model Membranes. CRC Press, 2014. http://dx.doi.org/10.1201/b16617-20.

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Batra, Unnati, Tejashree Waghule, Ranendra N. Saha, and Gautam Singhvi. "Liposomal Drug Delivery." In Nanoparticles and Nanocarriers-Based Pharmaceutical Formulations. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815049787122010013.

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Liposomes are emerging as uni or multilamellar micro particulate phospholipid bilayer sphere vesicles, which can be produced synthetically and have the ability to encapsulate any kind of drug molecule. Either hydrophilic or lipophilic drug substances can be easily entrapped in these vesicles for efficient delivery of a drug. Over the past decades, these have been under investigation to develop novel and revolutionary drug delivery aspects in the pharmaceutical field. Liposomes are based on a simple mechanism of formation of the enclosed sphere formed when amphiphilic lipid comes in contact wit

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Conference papers on the topic "Bilayer formulation"

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Jia, Ru, Duy Nguyen, Boyd Laurent, and Jeremy Moloney. "Investigation on the Mechanism of Corrosion Inhibitors by Contact Angle and Surface Tension." In CONFERENCE 2024. AMPP, 2024. https://doi.org/10.5006/c2024-21173.

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Abstract Corrosion is common, costly and a prevalent industrial problem in the oil and gas industry. Corrosion inhibitors, which are surfactant-like molecules, adsorb on the metallic surface of a pipe to form a barrier film that inhibits interactions of the pipe surface with corrosive species. Despite the prominence of surfactants as corrosion inhibitors, their adsorption behavior inside a pipeline is not well understood. In this study, continuous corrosion inhibitors were evaluated to correlate corrosion performance testing with contact angle and surface tension studies. Contact angle method

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Brunsvold, W., C. Lyons, W. Conley, D. Crockatt, M. Skinner, and A. Uptmor. "Advanced Bilayer Resist Process With Optimized PMGT Formulation." In 1989 Microlithography Conferences, edited by Elsa Reichmanis. SPIE, 1989. http://dx.doi.org/10.1117/12.953041.

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Alapati, Raghava, Dorel Moldovan, and Ram Devireddy. "Atomistic Simulation of Pore Formation in Lipid Bilayers in the Presence of Dimethylsulfoxide: Further Evidence for Entropic Driven Pore Formation." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192793.

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In a recent study, Moldovan et al [1] have demonstrated that in the presence of 11.3 mol% dimethylsulfoxide (DMSO) a pore can nucleate and grow spontaneously in a lipid bilayer even in the absence of an externally applied stresses or electric field. The authors rationalized the spontaneous pore nucleation, in the absence of any external driving force, by considering the combined effect of the entropy of pore shape fluctuation and the significant decrease of the bilayer line tension in the presence of DMSO. Building on the classical nucleation theory developed three decades ago by Lister [2] th

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Tsai, Yi-Chia, Ming-Yi Lee, Yiming Li, and Seiji Samukawa. "Miniband formulation of bilayer type II Ge/Si quantum dot superlattices." In 2016 IEEE 16th International Conference on Nanotechnology (IEEE-NANO). IEEE, 2016. http://dx.doi.org/10.1109/nano.2016.7751492.

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Erceg, Tamara, Olja Šovljanski, Ana Tomić, et al. "The influence of different plasticizers on the mechanical properties of active edible bilayer films." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.217e.

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In addition to potentially resolving environmental issues that come from plastic and food waste, active biodegradable packaging is being developed to increase the shelf life, quality, and safety of packaged food. In order to overcome the drawbacks of monolayer hydrocolloid-based coating, such as poor mechanical and barrier properties, the design of bilayer hydrocolloid-based coating has been structured using pullulan and gelatin. Sugar alcohols are widely used for the plasticizing of biopolymer-based films. The aim of this work is to investigate the influence of different sugar alcohols – xyli

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Freeman, Eric C., Michael K. Philen, and Donald J. Leo. "Principles of Biomolecular Network Design." In ASME 2013 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/smasis2013-3113.

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Networks of biomolecular unit cells are proposed as a new type of biologically inspired intelligent materials. These materials are derived from natural cellular mechanics and aim to improve current biologically-inspired technologies by recreating the desired systems from the basic building block of the natural world; the cell. The individual biomolecular unit cell is able to replicate natural cellular abilities through a combination of lipid bilayer membranes containing embedded proteins and peptides. While individual unit cells offer an ideal testing environment for demonstrating proofs of co

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Danso, D. K., Jozef Bicerano, Douglas P. Heller, and R. G. Barati. "Development of Polyelectrolyte Complex Nanoparticles for Direct Lithium Extraction from Oilfield Brines." In SPE Energy Transition Symposium. SPE, 2024. http://dx.doi.org/10.2118/221397-ms.

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Abstract This paper details the formulation and characterization of a novel nanoparticle system composed of polyethyleneimine (PEI) and dextran sulfate (DS) for direct lithium extraction (DLE) from bulk oilfield brines sourced from North America. Different mass ratios of solutions of PEI and DS at varied concentrations (1 -10wt%) were prepared in the presence of 150 ppm Li concentration to yield nanoparticle systems that electrostatically entrap the Li ions in the solution. The nanoparticles produced were characterized by their size, zeta potential (charge), polydispersity index, and count rat

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Tartis, Michaelann S., Jan Marik, Azadeh Kheirolomoom, et al. "Pharmacokinetics of Encapsulated Paclitaxel: Multi-Probe Analysis With PET." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176435.

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We have combined two imaging probes and used PET as a means to provide image-based validation for a novel targeted drug delivery system. The first probe was a direct labeling of the drug [18F]fluoropaclitaxel [1–3], which was inserted into various carrier vehicle formulations. The second probe, [18F]fluoro-1,2-dipalmitoyl-sn-glycerol, i.e. [18F]FDP involved radiolabeling the lipid vehicle. Paclitaxel, which is poorly soluble in aqueous media, also has limited solubility and stability in lipophilic environments such as liposomes. Stable association of paclitaxel with the lipid bilayer is affect

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Ma, Wentao, Xuning Zhao, and Kevin Wang. "A Fluid-Structure Coupled Computational Model for the Certification of Shock-Resistant Elastomer Coatings." In ASME 2020 39th International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/omae2020-18501.

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Abstract Shock waves from underwater and air explosions are significant threats to surface and underwater vehicles and structures. Recent studies on the mechanical and thermal properties of various phase-separated elastomers indicate the possibility of applying these materials as a coating to mitigate shock-induced structural failures. To demonstrate this approach and investigate its efficacy, this paper presents a fluid-structure coupled computational model capable of predicting the dynamic response of air-backed bilayer (i.e. elastomer coating – metal substrate) structures submerged in water

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