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1

Tavoloni, Nicola. "Biliary excretion of inorganic electrolytes: its role in hepatic bile formation." Canadian Journal of Physiology and Pharmacology 63, no. 10 (1985): 1245–51. http://dx.doi.org/10.1139/y85-206.

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To define the role of inorganic electrolyte secretion in hepatic bile formation, the effects of secretin, glucagon, and differently structured bile acids on bile flow and composition were studied in the dog, guinea pig, and rat. In the dog and guinea pig, secretin (2.5–10 clinical units∙kg−1∙30 min−1) increased bile flow and bicarbonate concentration in bile, a finding consistent with the hypothesis that the hormone stimulates a bicarbonate-dependent secretion possibly at the level of the bile ductule–duct. In the rat, secretin (5–15 CU∙kg−1∙30 min−1) failed to increase bile secretion. Glucago
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2

Fasano, Alessio, Maria Carmela Verga, Francesco Raimondi, and Stefano Guandalini. "Effects of Deconjugated Bile Acids on Electrolyte and Nutrient Transport in the Rabbit Small Intestine In Vitro." Journal of Pediatric Gastroenterology and Nutrition 18, no. 3 (1994): 327–33. http://dx.doi.org/10.1002/j.1536-4801.1994.tb11183.x.

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To obtain new information on the poorly investigated mechanisms of the diarrheogenic effects of bile acids, we investigated the effects of the unconjugated bile acids chenodeoxycholate and ursodeoxycholate on the small intestine transport of electrolytes and nutrients in the rabbit jejunal and ileal mucosa mounted in vitro in Ussing or influx chambers. When added to the ileal mucosa at a concentration of 1 m M, both bile acids induced a secretory shift in ion transport; absorption of Na and Cl was abolished and secretion of bicarbonate was enhanced. No changes in short circuit current or elect
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3

Zsembery, Akos, Theresia Thalhammer, and Jürg Graf. "Bile Formation: a Concerted Action of Membrane Transporters in Hepatocytes and Cholangiocytes." Physiology 15, no. 1 (2000): 6–11. http://dx.doi.org/10.1152/physiologyonline.2000.15.1.6.

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A large number of membrane transport mechanisms in hepatocytes and cholangiocytes serves for the secretion of bile acids, various other organic anions, organic cations, lipids, and electrolytes. After their functional characterization, some of these mechanisms' individual transport molecules are now identified, allowing better understanding of inherited and acquired disorders of bile formation.
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4

Huang, Rang-Lang, Wen-Kai Huang, Xiang-Yi Xiao, Lin-Feng Ma, He-Zi-Rui Gu, and Guo-Ping Yang. "Diagnosis and treatment of post-cholecystectomy diarrhoea." World Journal of Gastrointestinal Surgery 15, no. 11 (2023): 2398–405. http://dx.doi.org/10.4240/wjgs.v15.i11.2398.

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The incidence of cholecystitis is relatively high in developed countries and may usually be attributed to gallstones, the treatment for which involves complete surgical removal of the gallbladder (cholecystectomy). Bile acids produced following cholecystectomy continue to flow into the duodenum but are poorly absorbed by the colon. Excessive bile acids in the colon stimulate mucosal secretion of water and electrolytes leading, in severe cases, to diarrhoea. Bile acid diarrhoea (BAD) is difficult to diagnose, requiring a comprehensive medical history and physical examination in combination with
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5

Khan, Fatir Dad, Motasim Billah, Sultan Zeb, Mohammad Usman, and Syed Aamer Hussain. "Bile duct injury during laparoscopic cholecystectomy." International journal of health sciences 7, S1 (2023): 460–67. http://dx.doi.org/10.53730/ijhs.v7ns1.14225.

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Background and Aim: Bile duct injuries (BDIs) are complex complications developed during laparoscopic cholecystectomy leading to the postoperative morbidity and mortality. Auxiliary bile duct injury, vascular structures injuries, portal vein, cyst duct leakage and damage to right hepatic artery are caused by bile duct injuries. The purpose of the present study was to investigate the incidence, clinical presentation, and treatment modality of bile duct injuries during laparoscopic cholecystectomy. Patients and Methods: This descriptive case series was conducted on 96 extra hepatic biliary injur
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6

Ammon, H. V., D. S. Cho, R. L. Loeffler, and K. L. Reetz. "Effects of taurodeoxycholate on in vivo water and solute transport in rat jejunum in absence and presence of calcium." American Journal of Physiology-Gastrointestinal and Liver Physiology 250, no. 2 (1986): G248—G251. http://dx.doi.org/10.1152/ajpgi.1986.250.2.g248.

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Bile acids and fatty acids enhance the permeability of brush-border membrane vesicles for calcium. It has been postulated that increased influx of calcium into the enterocyte might be responsible for the fluid secretion induced by dihydroxy bile acids and fatty acids. During in vivo perfusion studies of the rat jejunum, 15 mM taurodeoxycholate induced secretion of electrolytes and water (P less than 0.001), reduced glucose absorption (P less than 0.001), and enhanced the absorption of mannitol (P less than 0.0125) and calcium (P less than 0.001). Calcium absorption continued to be enhanced dur
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7

Rodriguez, Myrian R., Leandro R. Soria, María S. Ventimiglia, et al. "Endothelin-1 and -3 induce choleresis in the rat through ETB receptors coupled to nitric oxide and vagovagal reflexes." Clinical Science 125, no. 11 (2013): 521–32. http://dx.doi.org/10.1042/cs20120633.

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We have reported previously that centrally applied ET (endothelin)-1 and ET-3 induce either choleresis or cholestasis depending on the dose. In the present study, we sought to establish the role of these endothelins in the short-term peripheral regulation of bile secretion in the rat. Intravenously infused endothelins induced significant choleresis in a dose-dependent fashion, ET-1 being more potent than ET-3. Endothelins (with the exception of a higher dose of ET-1) did not affect BP (blood pressure), portal venous pressure or portal blood flow. ET-1 and ET-3 augmented the biliary excretion o
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8

Okolo, Charles, Thomas Wong, Mark W. Moody, and Toan D. Nguyen. "Effects of bile acids on dog pancreatic duct epithelial cell secretion and monolayer resistance." American Journal of Physiology-Gastrointestinal and Liver Physiology 283, no. 5 (2002): G1042—G1050. http://dx.doi.org/10.1152/ajpgi.00436.2001.

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Pancreatic duct epithelial cells (PDEC) mediate the secretion of fluid and electrolytes and are exposed to refluxed bile. In nontransformed cultured dog PDEC, which express many ion transport pathways of PDEC, 1 mM taurodeoxycholic acid (TDCA) stimulated an125I−efflux inhibited by DIDS and 5-nitro-2-(3-phenylpropylamino)benzoic acid (NPPB) and a86Rb+efflux inhibited by charybdotoxin. Inhibition by 1,2-bis(2-aminophenoxy)ethane- N,N,N′,N′-tetraacetic acid (BAPTA)-AM suggests mediation via increased intracellular Ca2+concentration, whereas the absence of lactate dehydrogenase release excludes ce
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9

Hegyi, Peter, Jozsef Maléth, Julian R. Walters, Alan F. Hofmann, and Stephen J. Keely. "Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease." Physiological Reviews 98, no. 4 (2018): 1983–2023. http://dx.doi.org/10.1152/physrev.00054.2017.

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Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and fluid to and from the luminal contents. At the same time, epithelial cells are responsible for forming a physical and biochemical barrier that prevents the entry into the body of harmful agents, such as bacteria and their toxins. Dysregulation of epithelial transport and barrier function is associated with the pathogenesis of a number of conditions throughout the intestine, such as inflammatory bowel diseas
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10

Smeets-Peeters, Marianne, Tim Watson, Mans Minekus, and Robert Havenaar. "A review of the physiology of the canine digestive tract related to the development ofin vitrosystems." Nutrition Research Reviews 11, no. 1 (1998): 45–69. http://dx.doi.org/10.1079/nrr19980005.

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AbstractFood and nutrition studies in animals and human beings often meet with technical difficulties and sometimes with ethical questions. An alternative to research in living animals is the dynamic multicompartmentalin vitromodel for the gastrointestinal tract described by Minekuset al.(1995) and Havenaar & Minekus (1996). The dynamic conditions that are simulated in this model are peristaltic movements, transit times, pH responses, secretion of enzymes and electrolytes and absorption of nutrients and water. To obtain data for anin vitromodel of the dog gastrointestinal tract, the litera
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11

Anthone, Gary J., M. Kevin Barry, and Charles J. Yeo. "Site specificity and meal stimulation of the intestinal absorption of water, electrolytes, and bile acids." American Journal of Surgery 165, no. 6 (1993): 704–7. http://dx.doi.org/10.1016/s0002-9610(05)80792-5.

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12

Nze, P.O., O.E. Edebiri, O.H. Blackie, et al. "The Ameliorating Effect of The Velvet Tamarind (Icheku) Fruit Pulp of Ethanol Extraction on Some Gastrointestinal Functions in Adult Wistar Rats." Research and Reviews: Journal of Holistic Nursing 2, no. 2 (2025): 12–39. https://doi.org/10.5281/zenodo.15461517.

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<em>Velvet tamarind is used in folk medicine for the management of gastrointestinal disease. In this study, the effect of the fruit pulp extract on some gastrointestinal function prepared from the fruit pulp was subjected to analysis and the acute toxicity (LD50) evaluated rates. The effects on gastrointestinal function were studied in different experimental groups of the animals. In the first section, 20 adult Wistar rats were assigned to four (4) groups of five (5) rats each we studied. Group one served as control while group 2, 3, and 4 were treated with 250, 500, and 1000mg/kg of the extra
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13

Xu, Yue, Hang Zhang, Nannan Li, et al. "Preclinical Pharmacokinetic Studies of a Novel Diuretic Inhibiting Urea Transporters." Molecules 27, no. 8 (2022): 2451. http://dx.doi.org/10.3390/molecules27082451.

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Urea transporter (UT) inhibitors are a class of promising novel diuretics that do not cause the imbalance of Na+, K+, Cl−, and other electrolytes. In our previous studies, 25a, a promising diuretic candidate inhibiting UT, was discovered and showed potent diuretic activities in rodents. Here, a sensitive liquid chromatography–tandem mass spectrometry method for the quantitation of 25a in rat plasma, urine, feces, bile, and tissue homogenates was developed and validated to support the preclinical pharmacokinetic studies. The tissue distribution, excretion, and plasma protein binding were invest
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14

Lin, CS, GH Chiang, CH Liu, et al. "Comparison of a full-spectrum multi-analyte clinical analyser with six reference instruments using canine and feline blood samples." Veterinární Medicína 62, No. 6 (2017): 342–50. http://dx.doi.org/10.17221/109/2016-vetmed.

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In this study, we report the characterisation of a novel centrifugation and spectrum-integrated veterinary clinical analyser, the AmiShield&lt;sup&gt;TM&lt;/sup&gt;, which has been developed for the multiplex measurement of biochemical, electrolyte and immunoassay parameters in a point-of-care testing environment. The aims of this study were to evaluate the analytical performance of the AmiShield&lt;sup&gt;TM&lt;/sup&gt; and to compare it with six reference instruments using clinical blood samples. Two hundred and four canine and 120 feline blood samples collected from veterinary teaching hosp
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15

Keely, Stephen J., and Kim E. Barrett. "Intestinal secretory mechanisms and diarrhea." American Journal of Physiology-Gastrointestinal and Liver Physiology 322, no. 4 (2022): G405—G420. http://dx.doi.org/10.1152/ajpgi.00316.2021.

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One of the primary functions of the intestinal epithelium is to transport fluid and electrolytes to and from the luminal contents. Under normal circumstances, absorptive and secretory processes are tightly regulated such that absorption predominates, thereby enabling conservation of the large volumes of water that pass through the intestine each day. However, in conditions of secretory diarrhea, this balance becomes dysregulated, so that fluid secretion, driven primarily by Cl− secretion, overwhelms absorptive capacity, leading to increased loss of water in the stool. Secretory diarrheas are c
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16

Singh, Shailendra Pal, Pradeep Kumar Singh, Praveen Singh, Shashank Verma, and Krishna Kumar Tiwari. "Correlation of prolonged fasting and gall bladder sludge formation after emergency G. I. surgery." International Surgery Journal 4, no. 8 (2017): 2546. http://dx.doi.org/10.18203/2349-2902.isj20173206.

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Background: After emergency laparotomy due to some intestinal pathology patient are kept fasting to rest the bowel so that repaired pathology could get the proper time for healing. And during this period body’s nutritional requirement are replenished either by total parenteral nutrition or other intravenous fluids containing glucose and electrolytes. The major complication of TPN is liver disease that most commonly include steatosis, cholestasis, Cholelithiasis. Development of cholestasis, biliary sludge, and gall stone are due to loss of enteric stimulation and not directly linked to TPN. The
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17

Kimura, Tohru, and Kengo Inaka. "The First Case Report of Ectopic Hepatic Tissue in a Guinea Pig." Case Reports in Veterinary Medicine 2021 (January 23, 2021): 1–5. http://dx.doi.org/10.1155/2021/6626299.

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Ectopic hepatic tissue is an extremely rare developmental abnormality in human beings. Although this lesion is likewise rare in veterinary medicine and there were sparse reports in several species such as dogs, cats, cows, and calves, we incidentally encountered ectopic hepatic tissue in a guinea pig. In the case of guinea pigs, we report for the first time the occurrence of ectopic hepatic tissue implanted in the gallbladder. The healthy guinea pig remained asymptomatic, and its macroscopic findings also showed no abnormalities. Hematological examinations exhibited moderate decreases in white
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18

Sobh, Mahmoud, Mohamed Abdalbary, Mostafa Abdelsalam, and Amr El-Husseini Mohamed. "Renal Dysfunction in Patients with Liver Cirrhosis." Digestive Disease Interventions 06, no. 02 (2022): 131–36. http://dx.doi.org/10.1055/s-0042-1746192.

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AbstractLiver cirrhosis is a major health problem that can affect people of different ages. It induces pivotal hemodynamic and metabolic systemic disturbances along with other organs dysfunction. Renal dysfunction in cirrhotic patients is not uncommon, and subtle renal impairment is an early and very frequent finding. Liver cirrhosis can afflict kidney functions through different mechanisms. Renal vasoconstriction is usually the initial response of splanchnic vasodilation and decreased effective renal plasma flow. This induces a reduction of intraglomerular pressure leading to stimulation of r
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19

Onu, A., Y. Saidu, M. J. Ladan, L. S. Bilbis, A. A. Aliero, and S. M. Sahabi. "Effect of Aqueous Stem Bark Extract ofKhaya senegalensison Some Biochemical, Haematological, and Histopathological Parameters of Rats." Journal of Toxicology 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/803835.

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The subchronic effect of aqueous stem bark extract ofKhaya senegalensison some biochemical, haematological, and histopathological parameters of rats was investigated. The rats were divided into six groups of five rats per group. Groups I to VI were administered graded doses of 0, 400, 800, 1200, 1600, and 2000 mg/kg bw, respectively. The result of study revealed that administration of theKhaya senegalensisfor twenty-eight days at the experimental dose resulted in significant (P&lt;0.05) increase in urea, electrolytes (Na+, K+), and creatinine levels. The extract also significantly (P&lt;0.05)
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20

Strasberg, S. M., R. G. Ilson, and C. E. Bear. "Bile salt dependent bile flow in the rabbit: evidence for the importance of an amiloride inhibitabie pathway." Canadian Journal of Physiology and Pharmacology 64, no. 10 (1986): 1316–20. http://dx.doi.org/10.1139/y86-222.

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Bile salt dependent flow and electrolyte secretion in response to two bile salts were studied in awake rabbits. It was found that sodium glycodeoxycholate had a much greater choleretic and cholioneretic efficiency than sodium taurocholate. The effect of the bile salts on flow and electrolyte secretion was not linear across the range of bile salt secretion rates studied. When amiloride was administered significant decreases in choleretic and cholioneretic efficiencies occurred, but furosemide had no effect. It is concluded that bile salts stimulate electrolyte transport via amiloride inhibitabl
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21

Bucking, Carol, and Chris M. Wood. "Gastrointestinal processing of Na+, Cl−, and K+ during digestion: implications for homeostatic balance in freshwater rainbow trout." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 291, no. 6 (2006): R1764—R1772. http://dx.doi.org/10.1152/ajpregu.00224.2006.

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The role of the gastrointestinal tract in maintaining ionic homeostasis during digestion, as well as the relative contribution of the diet for providing electrolytes, has been generally overlooked in many aquatic species. An experimental diet that contained an inert reference marker (lead-glass beads) was used to quantify the net transport of Na+, K+, and Cl− during the digestion and absorption of a single meal (3% ration) by freshwater rainbow trout ( Oncorhynchus mykiss). Secretion of Cl− into the stomach peaked at 8 and 12 h following feeding at a rate of 1.1 mmol·kg−1·h−1, corresponding to
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22

Chariot, J., C. Nagain, F. Hugonet, A. Tsocas, and C. Roze. "Control of interdigestive and intraduodenal meal-stimulated pancreatic secretion in rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 259, no. 2 (1990): G198—G204. http://dx.doi.org/10.1152/ajpgi.1990.259.2.g198.

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Mechanisms of neural (vagal and cholinergic) and hormonal [cholecystokinin (CCK)] control of pancreatic exocrine secretion were studied in basal interdigestive conditions and after stimulation by an intraduodenal meal in rats equipped with a semichronic pancreatic fistula. Bile was recirculated into the duodenum, and a solution of trypsin and electrolytes was continuously infused. Pancreatic secretion was compared in control experiments, after vagotomy, and after venous infusion of cholinergic and CCK antagonists. Basal pancreatic secretion was decreased by atropine, pirenzepine, and hexametho
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23

Falcón-Cancino, Luis A., Ernesto Baltazar-Herrera, Alejandro A. Flores-López, et al. "Drainage of the hepatic cyst by laparoscopy - clinical case." International Journal of Research in Medical Sciences 11, no. 4 (2023): 1361–64. http://dx.doi.org/10.18203/2320-6012.ijrms20230892.

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Liver cysts are formations of serous content surrounded by normal liver parenchyma, without communication with the bile duct. The cyst wall is generally lined with cuboidal epithelium surrounded by layers of connective tissue. They are rare entities in adult patients, generally, they are asymptomatic in 3%, and between 10-15% of all patients will generate symptoms that lead them to consult. A 38-year-old man with an external abdominal tomography study that reported a giant hepatic cyst. Laboratory blood tests: hemoglobin 7.9 g/dl; leukocytosis 11,000/ul; serum electrolytes, liver transaminases
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24

Solomon, A. M. "The role of dietary fiber in functional nutrition." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 26, no. 101 (2024): 77–83. http://dx.doi.org/10.32718/nvlvet-f10112.

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The process of nutrition is a function of the relationship between a person and the environment. Food should contribute to the adaptation of the human body to unfavorable conditions and, in addition to its main function – meeting the physiological needs of the human body for nutrients and energy, also perform preventive and therapeutic tasks. Recently, the popularity of healthy food has increased. Experts predict that the market for functional products is growing every year. In this regard, in many countries, in-depth research is being carried out on the structure, composition, properties of d
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25

González, Carol, Daniela González, Rommy N. Zúñiga, Humberto Estay, and Elizabeth Troncoso. "Simulation of Human Small Intestinal Digestion of Starch Using an In Vitro System Based on a Dialysis Membrane Process." Foods 9, no. 7 (2020): 913. http://dx.doi.org/10.3390/foods9070913.

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This work deepens our understanding of starch digestion and the consequent absorption of hydrolytic products generated in the human small intestine. Gelatinized starch dispersions were digested with α-amylase in an in vitro intestinal digestion system (i-IDS) based on a dialysis membrane process. This study innovates with respect to the existing literature, because it considers the impact of simultaneous digestion and absorption processes occurring during the intestinal digestion of starchy foods and adopts phenomenological models that deal in a more realistic manner with the behavior found in
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26

Schlenker, T., and J. G. Fitz. "Ca(2+)-activated C1- channels in a human biliary cell line: regulation by Ca2+/calmodulin-dependent protein kinase." American Journal of Physiology-Gastrointestinal and Liver Physiology 271, no. 2 (1996): G304—G310. http://dx.doi.org/10.1152/ajpgi.1996.271.2.g304.

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Biliary epithelial cells contribute to bile formation through absorption and secretion of fluid and electrolytes. Recent studies indicate that membrane Cl- permeability is regulated in part by increases in intracellular Ca2+ concentration. The purpose of these studies was to evaluate the effects of intracellular Ca2+ on channel activity, using the human Mz-ChA-1 cholangiocarcinoma cell line as a model, and to assess the possible roles of Ca(2+)-dependent kinases in channel regulation. Exposure to ionomycin (1 microM) activated ion channels in the cell-attached configuration in 63 of 74 attempt
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27

Roma, Marcelo G., Cristina Carnovale, and Emilio A. Rodríguez Garay. "Bile salt-associated electrolyte secretion." Experimental and Toxicologic Pathology 44, no. 6 (1992): 354–60. http://dx.doi.org/10.1016/s0940-2993(11)80228-9.

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28

Cwikiel, W., J. Harnek, E. Zoucas, and U. Stenram. "Electrolytic stent in the normal bile duct." Acta Radiologica 39, no. 2 (1998): 157–60. http://dx.doi.org/10.1080/02841859809172170.

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Purpose: to evaluate and compare changes in the bile-duct wall after the insertion of electrolytic and nonelectrolytic stents Material and Methods: the electrolytic stents were composed of 3 different layers (iron, isolating polyethylene and tantalum) and were implanted surgically in the bile duct of 8 healthy pigs. the nonelectrolytic stents were also composed of 3 layers (2 layers of tantalum and an isolating layer of polyethylene) and were implanted surgically in the bile ducts of 9 healthy pigs. After an observation time of 8 weeks, the pigs were killed and the bile ducts were excised and
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29

Garcia-Marin, J. J., J. G. Redondo-Torres, F. Perez-Barriocanal, and M. M. Berenson. "Effect of protoporphyrin IX on ursodeoxycholate-induced hypercholeresis in the rat." Clinical Science 75, no. 6 (1988): 593–99. http://dx.doi.org/10.1042/cs0750593.

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1. It is known that the perfusion of rat livers with solutions containing protoporphyrin IX induces a decrease in bile flow which is not due to inhibition of bile acid secretion but rather to decreased electrolyte transport into bile. By contrast, ursodeoxycholate induces hypercholeresis, partly due to a marked stimulation of biliary bicarbonate secretion. The aim of the present work was to investigate the effect of protoporphyrin IX on ursodeoxycholate-induced choleresis in anaesthetized male Wistar rats. 2. Protoporphyrin IX infusion at rates of 10, 20 and 40 μg min−1 100 g−1 body weight int
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30

Bergholz, Carolyn M., Ronald J. Jandacek, and Alan BR Thomson. "Review of Laboraotory and Clinical Studies of Olestra, a Nonabsorbable Lipid." Canadian Journal of Gastroenterology 5, no. 4 (1991): 137–46. http://dx.doi.org/10.1155/1991/208460.

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The classical understanding of fat digestion and absorption is provided as background for a review of research on olestra, a triglyceride-derived lipid that is not digested or absorbed from the intestinal lumen. Olestra (formerly ‘sucrose polyester’) is the generic name proposed for the mixture of the hexa, hepta and octa long chain fatty acid esters of sucrose. Olestra has the physical properties of fat and can therefore function as a zero calorie fat replacement in foods. The fate and effects of olestra in the gastrointestinal tract have been extensively investigated in animals and humans. E
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31

Hollifield, Ian E., Natalya I. Motyka, Sydney R. Stewart, et al. "Heat-Stable Enterotoxin Secretions Assessed via ICP-MS Reveal Iron-Mediated Regulation of Virulence in CFA/I- and CS6-Expressing ETEC Isolates." Cells 12, no. 4 (2023): 567. http://dx.doi.org/10.3390/cells12040567.

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Enterotoxigenic Escherichia coli (ETEC) are a significant cause of childhood diarrhea in low-resource settings. ETEC are defined by the production of heat-stable enterotoxin (ST) and/or heat-labile enterotoxin (LT), which alter intracellular cyclic nucleotide signaling and cause the secretion of water and electrolytes into the intestinal lumen. ETEC take cues from chemicals (e.g., glycans, bile salts, and solutes) that may be liberated following enterotoxin activity to recognize entrance into the host. ETEC then alter the expression of surface adhesins called colonization factors (CFs) to atta
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32

Shoikhedbrod, Michael. "Juice concentration using juice electrolysis generated by solar cells of solar panel." BOHR International Journal of Engineering 2, no. 1 (2023): 38–42. http://dx.doi.org/10.54646/bije.2023.16.

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Juice concentrates are made by extracting water from freshly squeezed juice. Extracting water from fresh juice today is done by evaporation, freezing of the water, or using diaphragms. During evaporating, freshly squeezed juice is heated in a vacuum below the boiling point to preserve all its beneficial substances. When water freezes, it is removed by cold. When using diaphragms, freshly squeezed juice is passed through a membrane with tiny cells, as a result of which water penetrates through the membrane, and large molecules of freshly squeezed juice concentrate are deposited on the membrane.
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33

Andersen, Helene Bryde, Ljiljana Petronijevic, Birgitte Giese, Thorkild Mygind, and Flemming Burcharth. "Somatostatin Reduces Bile Secretion and Loss of Bile Constituents in Patients with External Biliary Drainage." HPB Surgery 9, no. 4 (1996): 229–33. http://dx.doi.org/10.1155/1996/12097.

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The effect of 24-hours continuous somatostatin 14 infusion on the volume of the bile secretion and on the bile composition were studied in seven patients with malignant biliary obstruction who had transhepatic external biliary drainage.The bile acid composition was measured with high performance liquid chromatography (HPLC). Somatostatin infusion significantly reduced the daily bile loss from median 473 ml to 140 ml (41 percent, p=0.01) with a concomitant significant reduction in the daily molar loss of cholesterol, triglyceride, Na+, K+, CI−, Ca++ and Mg++. The loss of chloride and sodium was
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34

Cwikiel, W., J. Harnek, E. Zoucas, and U. Stenram. "Electrolytic stent in the normal bile duct." Acta Radiologica 39, no. 2 (1998): 157–60. http://dx.doi.org/10.3109/02841859809172170.

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35

Joyce, Susan A., and Cormac G. M. Gahan. "Disease-Associated Changes in Bile Acid Profiles and Links to Altered Gut Microbiota." Digestive Diseases 35, no. 3 (2017): 169–77. http://dx.doi.org/10.1159/000450907.

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The gastrointestinal microbiota plays a central role in the host metabolism of bile acids through deconjugation and dehydroxylation reactions, which generate unconjugated free bile acids and secondary bile acids respectively. These microbially generated bile acids are particularly potent signalling molecules that interact with host bile acid receptors (including the farnesoid X receptor, vitamin D receptor and TGR5 receptor) to trigger cellular responses that play essential roles in host lipid metabolism, electrolyte transport and immune regulation. Perturbations of microbial populations in th
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36

NATHANSON, Michael H., Angela D. BURGSTAHLER, Anatoly MASYUK, and Nicholas F. LaRUSSO. "Stimulation of ATP secretion in the liver by therapeutic bile acids." Biochemical Journal 358, no. 1 (2001): 1–5. http://dx.doi.org/10.1042/bj3580001.

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ATP receptors are ubiquitously expressed and are potential targets for the therapy of a number of disorders. However, delivery of ATP or other nucleotides to specific tissues is problematic, and no pharmacological means to stimulate the release of endogenous ATP has been described. We examined the effects of the bile acid ursodeoxycholic acid (UDCA) on ATP release into bile, since this bile acid is the only agent known to be of therapeutic benefit in secretory disorders of the liver, and since its mechanism of action is not established. Both UDCA and its taurine conjugate stimulated secretion
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37

Shrestha, BR, M. R. Joshi, and T. P. Bohara. "Anaesthetic issues in Brugada electrocardiogram/syndrome undergoing laproscopic common bile duct exploration and laproscopic primary common bile duct closure." Journal of Kathmandu Medical College 2, no. 1 (2014): 36–39. http://dx.doi.org/10.3126/jkmc.v2i1.10555.

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Here we report a rare case of Brugada Syndrome in a young Nepalese male undergoing laparoscopic common bile ductexploration and laparoscopic primary common bile duct closure. Recognition of the disease, preparedness to tacklethe developing arrhythmias, avoidance of precipitating drugs, adopting policy of anaesthetic interventions to balancethe autonomic system, maintenance of normothermia and electrolyte balance, avoidance of hypoxia, hypercarbia andacidosis are the key to management of this disease in anaesthetic pursuit.DOI: http://dx.doi.org/10.3126/jkmc.v2i1.10555Journal of Kathmandu Medic
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38

Carrella, Massimino, Annalisa Csillaghy, Renato de Mercato, and Agesilao D'Arienzo. "Biliary Excretion of Chylomicron Remnant Cholesterol in the Rat: Responses to the Expansion of Their Plasma Pool and Promoting Role of Stimulated Bile-Acid Synthesis." Clinical Science 89, no. 2 (1995): 121–28. http://dx.doi.org/10.1042/cs0890121.

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1. Chylomicron remnants, the intermediate intestinal lipoproteins carrying the bulk of dietary cholesterol, are actively taken up and degraded in the hepatocytes, releasing cholesterol which can be excreted in bile. To study this pathway, a mass of remnants, leading to a consistent rise in hepatic cholesterol, was administered as an intravenous bolus in rats with chronic bile fistula equilibrated by water, electrolyte and taurocholate infusions, and changes in biliary lipids and bile acids were evaluated for up to 24 h in comparison with baseline. 2. A mean 16% increase in the net output of bi
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39

Sebenji, Ana, Mihalj Pоsa, Nevena Grujic-Letic, and Kosta Popovic. "Influence of the structure of bile acids on their partition coefficient in dibutyl ether and chloroform." Zbornik Matice srpske za prirodne nauke, no. 128 (2015): 77–85. http://dx.doi.org/10.2298/zmspn1528077s.

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Bile acids are well known natural surfactants able to modify the per?meability of biological membranes. The logarithm of partition coefficient between, tradi?tionally used, n-octanol and water is a measure of lipophilicity as a predictor of solute membrane partitioning. The aim of this work was to determine partition coefficients of bile acids in a mixture of water and chloroform and dibutyl ether at different pH values and with addition of different concentrations of sodium ions, and to examine the influence of the structure of bile acid nucleus on measured partition coefficients. Partition c
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40

Bear, Christine E., and Eldon A. Shaffer. "Hepatocellular water and electrolyte secretion." Canadian Journal of Physiology and Pharmacology 66, no. 10 (1988): 1253–60. http://dx.doi.org/10.1139/y88-206.

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The study of hepatocellular water and electrolyte secretion has been hampered because of the inaccessibility of the hepatobiliary secretory lumen, the canaliculus. The advent of novel experimental models has allowed the application of electrophysiological techniques to investigate the ionic basis of hepatocellular secretion. The "hepatocyte couplet" isolated from the liver in primary monolayer cultures consists of two hepatocytes which enclose a single canalicular unit. The canaliculus of the couplet appears to behave as it would in vivo, exhibiting both secretory and contractile activity. Int
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41

Anwer, M. S. "Effects of ion substitution on transport and choleretic effect of ouabain." American Journal of Physiology-Gastrointestinal and Liver Physiology 252, no. 3 (1987): G357—G364. http://dx.doi.org/10.1152/ajpgi.1987.252.3.g357.

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The role of inorganic ions in hepatic transport and choleretic effect of ouabain was studied in isolated perfused rat liver to verify whether Na+-coupled ouabain uptake into hepatocytes is responsible for the choleretic effect. Hepatic uptake and clearance of ouabain were not significantly affected when perfusate Na+ was replaced by Li+ or choline+, chloride by nitrate or isethionate, or bicarbonate by tricine. However, these ion substitutions, with the exception of Li+, significantly reduced ouabain-induced choleresis and biliary electrolyte excretion. When ouabain was infused at different ra
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42

Aleman, Ricardo S., Dany Avila, Allan Avila, et al. "Effects of Weevil (Rhynchophorus palmarum), Teosinte (Dioon mejiae) and Caesar’s Mushroom (Amanita caesarea) on the Properties of Lactobacillus acidophilus LA-K." Fermentation 9, no. 9 (2023): 852. http://dx.doi.org/10.3390/fermentation9090852.

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Weevil (Rhynchophorus palmarum) powder, teosinte (Dioon mejiae) and Caesar’s mushroom (Amanita caesarea) flour have bioactive compounds with significant nutritional applications. This paper aimed to examine the influence of weevil, teosinte, and mushroom powders on the protease activity, acid tolerance, bile tolerance, lysozyme tolerance, and gastric juice resistance ability of Lactobacillus acidophilus LA-K. Acid tolerance was determined by adjusting the pH of MRS broth to 2.0 for L. acidophilus incubated under aerobic conditions at 37 °C. Bile tolerance was determined by incorporating 0.3% o
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Aleman, Ricardo S., Franklin Delarca, Mallerly Sarmientos, Jhunior Marcia, Ajitesh Yaday, and Aryana Kayanush. "Impact of Novel Functional Ingredients on Lactobacillus casei Viability." Bacteria 3, no. 1 (2024): 30–41. http://dx.doi.org/10.3390/bacteria3010003.

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Nipple fruit (Solanum mammosum), teosinte (Dioon mejiae), Caesar mushroom (Amanita caesarea), and weevil (Rhynchophorus palmarum) powders have shown great nutritional content with meaningful dietary applications. This study aspired to investigate the impact of nipple fruit, teosinte, Caesar mushroom, and weevil powders on the bile tolerance, acid tolerance, lysozyme tolerance, gastric juice resistance, and protease activity of Lactobacillus casei. Nipple fruit, teosinte, Caesar mushroom, and weevil powders were combined at 2% (wt/vol), whereas the control samples did not include the ingredient
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44

Aleman, Ricardo S., Dany Avila, Allan Avila, et al. "Chemical Characterization and Impact of Nipple Fruit (Solanum mammosum) on the Characteristics of Lactobacillus acidophilus LA K." Fermentation 9, no. 8 (2023): 715. http://dx.doi.org/10.3390/fermentation9080715.

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Nipple fruit (Solanum mammosum) has been considered to have great pharmaceutical potential because of its high amounts of solamargine and solasonine. This study aimed to examine the effect of nipple fruit at different concentrations (0.5%, 1%, and 2% (w/v)) on the viability, acid, bile, lysozyme, and gastric juice tolerance, and protease activity of Lactobacillus acidophilus LA K. The viability was studied in MRS broth. Acid tolerance was determined by adjusting the pH to 2, whereas bile tolerance was examined with oxgall 0.3% (w/v) in MRS broth. Lysozyme resistance was investigated in an elec
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45

RaimoiKll, F., A. Fasno, M. C. Verga, and S. Guandalini. "57 EFFECTS OF DECONJUGATED BILE ACIDS ON SMALL INTESTINAL ELECTROLYTE AND NUTRIENT TRANSPORT." Journal of Pediatric Gastroenterology and Nutrition 15, no. 3 (1992): 350. http://dx.doi.org/10.1097/00005176-199210000-00081.

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46

RaimoiKll, F., A. Fasno, M. C. Verga, and S. Guandalini. "57 EFFECTS OF DECONJUGATED BILE ACIDS ON SMALL INTESTINAL ELECTROLYTE AND NUTRIENT TRANSPORT." Journal of Pediatric Gastroenterology and Nutrition 15, no. 3 (1992): 350. http://dx.doi.org/10.1002/j.1536-4801.1992.tb10727.x.

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47

Bonincontro, Adalberto, Angelo Antonio D'Archivio, Luciano Galantini, Edoardo Giglio, and Francesco Punzo. "X-ray, Electrolytic Conductance, and Dielectric Studies of Bile Salt Micellar Aggregates." Langmuir 16, no. 26 (2000): 10436–43. http://dx.doi.org/10.1021/la000844w.

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48

Dubey, Ishant. "Hydrogen fuel as Renewable energy source for Hybrid motorized vehicle." Edumania-An International Multidisciplinary Journal 01, no. 01 (2023): 11–20. http://dx.doi.org/10.59231/edumania/edmn8962.

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Hybrid Powered Bike with Energy Saver is a hybrid bike concept where bike will be run based on of water and battery powered. The oxygen and hydrogen gases generated through electrolysis will be used to power the bike piston engine. Another option is to use electric motor to power the bike. The proposed solution emphasizes on the use of environment friendly fuel. Implementing this system will enable us to reduce the cost of fuel and also make it less polluting. Impact: ● It will help us to overcome from the uses of Non-Renewable energy sources as they are limited. ● It will help us to overcome
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49

Wang, Yan-Ni, He-He Hu, Dan-Dan Zhang, et al. "The Dysregulation of Eicosanoids and Bile Acids Correlates with Impaired Kidney Function and Renal Fibrosis in Chronic Renal Failure." Metabolites 11, no. 2 (2021): 127. http://dx.doi.org/10.3390/metabo11020127.

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Chronic renal failure (CRF) is an irreversible deterioration of the renal functions that characterized by fluid electrolyte unbalance and metabolic-endocrine dysfunctions. Increasing evidence demonstrated that metabolic disturbances, especially dyslipidemia and profound changes in lipid and lipoprotein metabolism were involved in CRF. Identification of lipids associated with impaired kidney functions may play important roles in the understanding of biochemical mechanism and CRF treatment. Ultra-performance liquid chromatography coupled with high-definition mass spectrometry-based lipidomics wa
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50

Tietz, P. S., G. Alpini, L. D. Pham, and N. F. Larusso. "Somatostatin inhibits secretin-induced ductal hypercholeresis and exocytosis by cholangiocytes." American Journal of Physiology-Gastrointestinal and Liver Physiology 269, no. 1 (1995): G110—G118. http://dx.doi.org/10.1152/ajpgi.1995.269.1.g110.

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Previous work from our laboratory has implicated hormone-induced plasma membrane movement (i.e., endo- and exocytosis) in water and electrolyte transport by the epithelial cells that line the ducts in the liver (i.e., cholangiocytes). To further explore the cellular mechanisms regulating ductal bile secretion, we infused somatostatin and/or secretin intravenously into rats 2 wk after either bile duct ligation (BDL), a procedure that induces selective proliferation of cholangiocytes, or sham surgery and measured bile flow and biliary constituents. We also determined the effect of somatostatin o
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