Academic literature on the topic 'Bio-met'
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Journal articles on the topic "Bio-met"
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Giromini, Carlotta, Marco Tretola, Cinzia Cristiani, Elisabetta Finocchio, Paolo Silacci, Sara Panseri, Matteo Dell’Anno, Antonella Baldi, and Luciana Rossi. "Evaluation of the Absorption of Methionine Carried by Mineral Clays and Zeolites in Porcine Ex Vivo Permeability Models." Applied Sciences 11, no. 14 (July 10, 2021): 6384. http://dx.doi.org/10.3390/app11146384.
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Supplemental dietary amino acids (AAs) need to be provided in a form that prevents their degradation along the gastrointestinal tract to guarantee their high bioavailability and bioactivity. In this study, methionine (Met) protected via organo-clay intercalation (natural carriers) has been developed as a sustainable alternative to polymeric coating. Specifically, two different bentonite-zeolite-based mineral clays were tested, Adsorbene (ADS) and BioKi (BIO). Briefly, 1 g of the carrier (ADS or BIO) was contacted with 50 mL of an aqueous solution at a pH of 3.0, 5.8, and 8.9. Solid-liquid separation was conducted. The released Met in the liquid phase was analysed by Chemical Oxygen Demand, while residual Met in the solid phase was analysed by Fourier Transform Infra-Red (FT-IR) spectroscopy. The effect of Met-ADS complex on cell viability was tested on IPEC-J2 cells incubated 3 h with Met-ADS 2.5 mM. Jejunum segments obtained by entire male pigs (Swiss Large White, body weight 100 ± 5 kg) were used as ex vivo models to compare the absorption of 2.5 mM Met released by ADS with 2.5 mM free Met and its influence on epithelial integrity in perfusion Ussing chambers. The carriers released a very low amount of Met and Met-BIO interaction was stronger than Met-ADS. The maximum release of Met was at pH 3, with 3% and 6% of Met release from Met-BIO and Met-ADS, respectively. Cell viability experiments revealed that Met-ADS did not alter cell metabolic activity. No differences in Met absorption and intestinal epithelial integrity were observed ex vivo between free Met and Met-ADS. This study provided new insights into the release of Met from natural clays such as ADS and BIO, the safety of its use in the porcine intestine and the ability of ADS-released Met to absorb to the same extent as the free Met in porcine jejunum.
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Le Curieux, F., and F. Nesslany. "Le "bio" nous met-il à l'abri des contaminants ?" Sciences des Aliments 28, no. 3 (June 28, 2008): 265–69. http://dx.doi.org/10.3166/sda.28.265-269.
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Walsh, John, and Dilip Kumar Jha. "Bio-Caps Nepal." South Asian Journal of Business and Management Cases 1, no. 1 (June 2012): 43–50. http://dx.doi.org/10.1177/227797791200100105.
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Bio-Caps India manufactures gelatin capsules for pharmaceutical manufacturers in India. The capsules are made in part from animal products, which represents an area of cultural sensitivity and requires the trust of end users and intermediaries who recommend specific drugs. Currently, Nepalese manufacturers deal with a single supplier and there is an opportunity for Bio-Caps to open a branch office in Kathmandu to work with local producers to provide better service. However, Nepal remains a poor country with very limited physical or business infrastructure, and it is far from certain that projected market demand can be met in circumstances of such uncertainty. The case focuses on the specific form and business model selected by the company and considers whether these are suitable for the environment to be explored.
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Zhang, Hong Yu, Jun Gu, Gui Qin Wang, Li Wei Hao, and Xue Qin Wu. "Influence of Aeration Modes on Aerobic Bio-Drying of Municipal Solid Waste (MSW)." Advanced Materials Research 1010-1012 (August 2014): 934–38. http://dx.doi.org/10.4028/www.scientific.net/amr.1010-1012.934.
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The process of biodrying could be a good solution for municipal solid waste management, allowing the production of fuel with an interesting energy content. In this study, bio-drying the mixed municipal solid waste (with the size among 15-80 mm) with different aeration modes were conducted. During the experiment, temperature, oxygen content and moisture content were determined, and continuous measurements of H2S and CH4 were taken. The results indicated that the thermophilic phases of all treatments beside T1 were met the Chinese standard of >55°C for 5-7 days for sanitation. The aeration mode of T4 was in favor of reduced the H2S and CH4 emission during MSW bio-drying. Under the condition of this study, the bio-drying cycle should be determined for 18 days. Intermittent ventilation mode is more effective to reduce the moisture content in MSW bio-drying process. So the aeration mode of T4 (2.0L/min, 30min run/30 min stop) was the first choice during MSW bio-drying.
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. "Overstap van een merk naar een merkloos product, hoe zit het met de bio-equivalentie?" Medisch-Farmaceutische Mededelingen 40, no. 7 (July 2002): 209. http://dx.doi.org/10.1007/bf03057988.
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Abergel, Élisabeth. "La connaissance scientifique aux frontières du bio-art : le vivant à l’ère du post-naturel." Cahiers de recherche sociologique, no. 50 (September 27, 2011): 97–120. http://dx.doi.org/10.7202/1005979ar.
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C’est en situant le concept du vivant tel qu’appréhendé par les technosciences et la nouvelle bio-économie, que le texte tente d’articuler la place du bio-art dans la production de la connaissance scientifique. La notion d’objet-frontière est utilisée afin de comprendre le dialogue qui peut s’établir entre deux mondes hétérogènes autour du statut du vivant. D’un côté, le monde de l’art qui met en scène le vivant dans ses oeuvres en le manipulant de manière créative et qui s’immisce dans la pratique scientifique et biogénétique à des fins « est-éthiques » et politiques, et qui tente d’interroger l’avenir de l’humain en explorant les possibilités du vivant. De l’autre côté, le monde scientifique qui tente de s’approprier le vivant en le redéfinissant dans le contexte de la bio-économie dans une logique endogène de production des savoirs. L’article explore les façons dont l’univers du bio-art, en intervenant dans le vivant, peut ouvrir de nouveaux espaces de réflexion sur le statut du vivant dans un monde post-naturel.
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Cuillerai, Marie, and Marc Abélès. "Mondialisation : du géo-culturel au bio-politique." Anthropologie et Sociétés 26, no. 1 (March 27, 2003): 11–28. http://dx.doi.org/10.7202/000700ar.
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Résumé La mondialisation est souvent décrite comme un phénomène principalement économique, et l’intérêt d’une approche anthropologique est d’en saisir la dimension géo-culturelle. Notre but est de faire apparaître tout l’intérêt de cette perspective en nous référant aux travaux d’Arjun Appadurai. Ce dernier met en évidence la crise de l’État-nation traditionnel et l’impact de la circulation des individus et des informations. Dans ce contexte, l’imagination joue un rôle essentiel, il est possible de produire de nouvelles localités. On confronte ici l’analyse d’Appadurai à une autre perspective qui souligne aussi l’importance des déplacements de population, mais place l’accent sur la dimension bio-politique de cette situation. En nous référant aux travaux de Michel Foucault et de Giorgio Agamben, nous montrerons que la prise en compte de cette perspective bio-politique peut permettre de mieux comprendre certains aspects de la mondialisation qui échappent à l’approche géo-culturelle.
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Le, Thi Thom, and Diem Hong Dang. "Cultivation and extraction of omega 3-6 fatty acids from the heterotrophic marine microalga Schizochytrium mangrovei TB17 to make a functional food." Research Journal of Biotechnology 16, no. 8 (July 25, 2021): 22–32. http://dx.doi.org/10.25303/168rjbt2221.
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The objective of this study was to investigate the different fermentation conditions for Schizochytrium mangrovei TB17 biomass production rich in omega-3 and omega-6 fatty acids to determine the optimal conditions for bio-oil extraction from the algal biomass and to study the pharmacological effects of this bio-oil in experimental animal models. After 108 h of fed-batch fermentation, the cell density, dry biomass, lipid contents and docosahexaenoic acid (DHA) contents reached 392.53±3.89×106 cells/mL, 100.41±3.17 g/L, 41.04±0.87% dry cell weight (DCW) and 33.33±1.96% total fatty acids (TFAs) respectively. The in situ transesterification producing bio-oil rich in omega 3-6 fatty acids from the biomass of the TB17 strain reached a yield of TFAs of 45.02±1.37% DCW. The yields of PUFAs and SFAs were 30.02±0.38% and 69.98±0.53% of TFA respectively. The bio-oil mainly contains DHA and EPA accounting for 74.04±0.25% and 10.97±0.43% of the TFAs respectively. The bio-oil met the Vietnam food safety standard. According to the results of the acute in mice and the subchronic oral toxicity in rats for 90 days, the bio-oil rich in omega 3-6 fatty acids is safe and has the ability to improve memory and learning ability in mice which can be made functional food oil capsules for human.
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Lord, Phillip, and Robert Stevens. "ISMB 2003 Bio-ontologies SIG and Sixth Annual Bio-ontologies Meeting Report." Comparative and Functional Genomics 4, no. 6 (2003): 663–66. http://dx.doi.org/10.1002/cfg.339.
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The Annual Bio-Ontologies meeting (http://www.cs.man.ac.uk/˜stevens/meeting03/) has now been running for 6 consecutive years, as a special interest group (SIG) of the much larger ISMB conference. It met in Brisbane, Australia, this summer, the first time it was held outside North America or Europe. The bio-ontologies meeting is 1 day long and normally has around 100 attendees. This year there were many fewer, no doubt a result of the distance, global politics and SARS. The meeting consisted of a series of 30 min talks with no formal peer review or publication. Talks ranged in style from fairly formal and complete pieces of work, through works in progress, to the very informal and discursive. Each year's meeting has a theme and this year it was ‘ontologies, and text processing’. There is a tendency for those submitting talks to ignore the theme completely, but this year's theme obviously struck a chord, as half the programme was about ontologies and text analysis (http://www.cs.man.ac.uk/˜stevensr/meeting03/programme.html). Despite the smaller size of the meeting, the programme was particularly strong this year, meaning that the tension between allowing time for the many excellent talks, discussion and questions from the floor was particular keenly felt. A happy problem to have!
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Gea, Saharman, Noni Oktari, Andriayani Andriayani, Sri Rahayu, and Averroes F. Piliang. "Comparative Optimization of Cellulase and Laccase Enzymes in Deinking Process of Used Newspapers." Jurnal Kimia Sains dan Aplikasi 23, no. 10 (October 8, 2020): 353–59. http://dx.doi.org/10.14710/jksa.23.10.353-359.
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The use of enzymes in the bio-deinking process of newspaper waste has promising potential. However, investigations on the concentration of enzyme combinations need to be carried out to obtain the optimum ratio of cellulase and laccase enzymes for the bio-deinking process of recycled newspapers. The mixture of the two enzymes at various ratios was used to remove the ink on paper pulp from used newspapers by mechanical disintegration method treatment and followed by the bio-deinking process in an incubator shaker. The characterization of functional groups, structures, and thermal properties of bio-deinked pulp paper was carried out by FTIR, XRD, DTG/TGA, and an analysis of the degree of brightness to the prepared paper. FTIR results confirmed three main components of papers, such as cellulose, hemicellulose, and lignin. The XRD results showed that the equal ratio of cellulase and laccase enzymes had an effect on a higher crystallinity index, which was 78.8% compared to those obtained from the conventional methods with a crystallinity index of 69.7%. Thermal analysis showed that the optimum combination of both enzymes contributed the most at the highest temperature where the rate of degradation decreased. Brightness analysis showed that bio-deinking had met the quality requirements for newsprint paper in SNI 7273:2008. Our findings show that the combination of cellulase and laccase enzymes at the same ratio can produce optimal bio-deinked pulp for paper fabrication with excellent characteristics in brightness, thermal, and physical properties.
Dissertations / Theses on the topic "Bio-met"
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Silva, J?nior Jos? Ferreira da. "Comportamento da adi??o do carbeto de ni?bio (nBC) na matriz met?lica do a?o ferr?tico 15kH2mfa." Universidade Federal do Rio Grande do Norte, 2012. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12804.
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Previous issue date: 2012-11-01Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico
The 15Kh2MFA steel is a kind of Cr-Mo-V family steels and can be used in turbines for energy generation, pressure vessels, nuclear reactors or applications where the range of temperature that the material works is between 250 to 450?C. To improve the properties of these steels increasing the service temperature and the thermal stability is add a second particle phase. These particles can be oxides, carbides, nitrites or even solid solution of some chemical elements. On this way, this work aim to study the effect of addition of 3wt% of niobium carbide in the metallic matrix of 15Kh2MFA steel. Powder metallurgy was the route employed to produce this metallic matrix composite. Two different milling conditions were performed. Condition 1: milling of pure 15Kh2MFA steel and condition 2: milling of 15Kh2MFA steel with addition of niobium carbide. A high energy milling was carried out during 5 hours. Then, these two powders were sintered in a vacuum furnace (10-4torr) at 1150 and 1250?C during 60 minutes. After sintering the samples were normalized at 950?C per 3 minutes followed by air cooling to obtain a desired microstructure. Results show that the addition of niobium carbide helps to mill faster the particles during the milling when compared with that steel without carbide. At the sintering, the niobium carbide helps to sinter increasing the density of the samples reaching a maximum density of 7.86g/cm?, better than the melted steel as received that was 7,81g/cm?. In spite this good densification, after normalizing, the niobium carbide don t contributed to increase the microhardness. The best microhardness obtained to the steel with niobium carbide was 156HV and to pure 15Kh2MFA steel was 212HV. It happened due when the niobium carbide is added to the steel a pearlitic structure was formed, and the steel without niobium carbide submitted to the same conditions reached a bainitic structure
O a?o 15Kh2MFA, da fam?lia dos a?os CrMoV, pode ser utilizado em turbinas para gera??o de energia, vasos de press?o, reatores nuclear ou aplica??es, onde o material ? submetido a temperaturas de servi?o entre 250 e 450?C. Uma forma de melhorar as propriedades do a?o, para que ele trabalhe a temperaturas mais altas ou que se torne mais est?vel ? adicionar part?culas de segunda fase na sua matriz. Estas part?culas podem estar na forma de ?xidos, carbetos, nitretos ou at? mesmo em solu??o s?lida quando alguns elementos qu?micos s?o adicionados ao material. Neste contexto, este trabalho objetiva estudar o efeito da adi??o de 3% de carbeto de ni?bio na matriz met?lica do a?o 15Kh2MFA. Para isto a metalurgia do p? foi a rota empregada para a produ??o deste comp?sito de matriz met?lica. Para tal, duas moagens distintas foram realizadas. A primeira com o a?o 15Kh2MFA e a segunda com o a?o 15Kh2MFA com adi??o de 3% de carbeto de ni?bio. A moagem de alta energia foi realizada durante 5 horas. Em seguida, os dois p?s produzidos foram sinterizados em um forno a v?cuo (10-4torr) a temperaturas de 1150?C e 1250?C durante 60 minutos. Ap?s a sinteriza??o as amostras foram submetidas ao tratamento t?rmico de normaliza??o a 950?C. Os resultados mostraram que a adi??o do carbeto de ni?bio ajuda o processo de cominui??o das part?culas, quando comparado com o a?o sem o carbeto de ni?bio. O carbeto de ni?bio tem um papel fundamental na densifica??o das amostras durante a sinteriza??o, levando a densidade 7,86g/cm?, que ? maior do que a densidade do a?o fundido recebido que era de 7,81g/cm?. Apesar desta boa densifica??o, ap?s a normaliza??o, o NbC n?o contribuiu de forma significativa para aumento da dureza, onde a melhor dureza obtida para o a?o com NbC foi de 156HV e para o a?o puro foi de 212HV. Isto se deve ao fato de que, quando o NbC foi adicionado ao a?o, formou-se uma estrutura perl?tica, enquanto que, com o a?o sem adi??o de NbC, submetido as mesmas condi??es, obteve-se uma estrutura bain?tica
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Braga, Renata Martins. "Pir?lise r?pida catal?tica do capim elefante utilizando materiais mesoporosos e ?xidos met?licos para deoxigena??o em bio-?leo." Universidade Federal do Rio Grande do Norte, 2012. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13017.
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Previous issue date: 2012-08-09Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico
The fast pyrolysis of lignocellulosic biomass is a thermochemical conversion process for production energy which have been very atratactive due to energetic use of its products: gas (CO, CO2, H2, CH4, etc.), liquid (bio-oil) and charcoal. The bio-oil is the main product of fast pyrolysis, and its final composition and characteristics is intrinsically related to quality of biomass (ash disposal, moisture, content of cellulose, hemicellulose and lignin) and efficiency removal of oxygen compounds that cause undesirable features such as increased viscosity, instability, corrosiveness and low calorific value. The oxygenates are originated in the conventional process of biomass pyrolysis, where the use of solid catalysts allows minimization of these products by improving the bio-oil quality. The present study aims to evaluate the products of catalytic pyrolysis of elephant grass (Pennisetum purpureum Schum) using solid catalysts as tungsten oxides, supported or not in mesoporous materials like MCM-41, derived silica from rice husk ash, aimed to reduce oxygenates produced in pyrolysis. The biomasss treatment by washing with heated water (CEL) or washing with acid solution (CELix) and application of tungsten catalysts on vapors from the pyrolysis process was designed to improve the pyrolysis products quality. Conventional and catalytic pyrolysis of biomass was performed in a micro-pyrolyzer, Py-5200, coupled to GC/MS. The synthesized catalysts were characterized by X ray diffraction, infrared spectroscopy, X ray fluorescence, temperature programmed reduction and thermogravimetric analysis. Kinetic studies applying the Flynn and Wall model were performed in order to evaluate the apparent activation energy of holoceluloce thermal decomposition on samples elephant grass (CE, CEL and CELix). The results show the effectiveness of the treatment process, reducing the ash content, and were also observed decrease in the apparent activation energy of these samples. The catalytic pyrolysis process converted most of the oxygenate componds in aromatics such as benzene, toluene, ethylbenzene, etc
A pir?lise r?pida da biomassa lignocelul?sica ? um processo de convers?o termoqu?mica para produ??o de energia que vem se tornando muito atratativo devido ao aproveitamento energ?tico de seus produtos: g?s (CO, CO2, H2, CH4, etc), l?quido (bio-?leo) e carv?o vegetal. O bio-?leo ? o principal produto da pir?lise r?pida, sendo a sua composi??o e caracter?sticas finais intrinsecamente relacionadas ? qualidade da biomassa (elimina??o de cinzas, teor de umidade, teor de celulose, hemicelulose e lignina) bem como ? efici?ncia da remo??o dos compostos oxigenados que causam caracter?sticas indesej?veis como aumento da viscosidade, instabilidade, corrosividade e baixo poder calor?fico. Os compostos oxigenados s?o originados no processo de pir?lise convencional da biomassa onde o uso de catalisadores s?lidos, em geral, permite a minimiza??o destes produtos melhorando a qualidade do produto final, o bio-?leo. O presente trabalho teve como objetivo avaliar os produtos da pir?lise catal?tica do capim elefante (Pennisetum purpureum Schum) utilizando catalisadores s?lidos, ?xidos a base de tungst?nio, suportados ou n?o em materiais mesoporosos do tipo MCM-41, derivados da s?lica da casca do arroz, visando ? redu??o de compostos oxigenados produzidos na pir?lise. O tratamento da biomasssa atrav?s da lavagem com ?gua aquecida (CEL) ou lavagem com solu??o ?cida (CELix), bem como a aplica??o de catalisadores a base de tungst?nio nos vapores provenientes do processo de pir?lise, teve a finalidade de melhorar a qualidade dos produtos da pir?lise. A pir?lise convencional e catal?tica da biomassa foram realizadas em um micro pirolisador, Py-5200, acoplado ao GC/MS. Os catalisadores sintetizados foram caracterizados por Difra??o de raios X, Espectroscopia na regi?o do infravermelho, Fluoresc?ncia de Raios X, Redu??o por Temperatura Programada e An?lise termogravim?trica. Estudos cin?ticos aplicando o modelo de Flynn Wall foram realizados com a finalidade de avaliar a energia de ativa??o aparente da decomposi??o t?rmica da holoceluloce nas amostras de capim elefante (CE, CEL e CELix). Os resultados mostraram a efici?ncia do processo de tratamento, reduzindo o teor de cinzas, como tamb?m foi observada a diminui??o na energia de ativa??o aparente dessas amostras. O processo de pir?lise catal?tica converteu a maioria dos produtos oxigenados do CE em arom?ticos como benzeno, tolueno, etilbenzeno, etc
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Maciel, Thais Aline Oliveira. "Estudo da influ?ncia de linf?citos TCD-8 e das c?lulas NK em casos de carcinoma epiderm?ide de l?bio inferior sem met?stase e com met?stase e sua rela??o com a progress?o da les?o." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17133.
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Previous issue date: 2014-02-26Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
The presence of inflammatory cells within the tumor microenvironment plays a dual role that may contribute both to the progression and for inhibition of tumor growth. Recent studies suggest that the quality, not the quantity, of the inflammatory infiltrate is the most important determinant for prognosis. Therefore, TCD8 cells and natural killer cells are the main effector cells in combating cancer. The aim of this study was to assess, through the immunohistochemical study, the expression of TCD8 lymphocytes and NK cells in epidermoid carcinoma (EC) of the lower lip. The sample consisted of 32 specimens of EC of the lower lip, of which 16 had regional lymph node metastasis, and the 16 remaining, free of metastases. The total number of positive cells at the front of invasion were evaluated quantitatively and the results were related to clinical TNM staging, histological grade of malignancy and prognostic factors. It was observed for the group with metastasis, prevalence of stages III and IV (p<0.0001). Most patients with metastasis, had a high grade of malignancy (p=0.006). Most cases classified as high grade of malignancy had stages III and IV (p=0.032). Of the total sample, there were three cases of recurrence and five with death, however these variables were not statistically significant when associated with clinicopathological parameters. The immunostaining of CD8 and CD57, respectively, showed no statistically significant association with any of the clinicopathological parameters studied, metastasis (p=0.346, p=0.622), TNM classification (p=0.146, p=0.576), histological grade of malignancy (p=0.936, p=936), recurrence (p=0.075, p=0.075) and death (p=0.897, p=0.856). Believing in the function of the immunological system against malignant cells, it is concluded that the TD8 lymphocytes and NK cells, would be acting in the control of the progression of malignant neoplasms, but not in isolated manner
A presen?a de c?lulas inflamat?rias dentro do microambiente tumoral exerce um papel dual podendo contribuir tanto para a progress?o como para a inibi??o do crescimento do tumor. Estudos recentes sugerem que a qualidade, e n?o a quantidade, do infiltrado inflamat?rio ? o determinante mais importante para o progn?stico. Portanto, as c?lulas TCD8 e as c?lulas natural killer (NK), s?o as principais c?lulas efetoras no combate do c?ncer. O objetivo desse trabalho foi avaliar, atrav?s do estudo imunoistoqu?mico, a express?o dos linf?citos TCD8 e das c?lulas NK em carcinoma epiderm?ide (CE) de l?bio inferior e sua rela??o com a progress?o da les?o. A amostra foi composta por 32 esp?cimes de CE de l?bio inferior, dos quais 16 apresentavam met?stase linfonodal regional, e os 16 restantes, livres de met?stase. O total de c?lulas positivas no front de invas?o foram avaliados de forma quantitativa e os resultados obtidos foram relacionados com estadiamento cl?nico TNM, grada??o histopatol?gica de malignidade e fatores progn?sticos. Observou-se para o grupo com met?stases, preval?ncia dos est?gios III e IV (p<0,0001). A maioria dos casos com met?stase, apresentava alto grau de malignidade (p=0,006). A maioria dos casos classificados como de alto grau de malignidade apresentava est?gios III e IV (p=0,032). Do total da amostra, houve tr?s casos com recidiva e cinco com ?bito, no entanto essas vari?veis n?o apresentaram diferen?a estatisticamente significativa quando associadas a par?metros clinico-patol?gicos. A imunoexpress?o do CD8 e do CD57, respectivamente, n?o apresentaram associa??o estatisticamente significativa com nenhum dos par?metros cl?nico patol?gicos estudados, met?stases (p=0,346; p=0,622); estadiamento cl?nico TNM (p=0,146; p=0,576) grada??o histopatol?gica de malignidade (p=0,936; p=936); recidiva (p=0,075; p=0,075) e ?bito (p=0,897; p=0,856). Acreditando na fun??o que o sistema imunol?gico possui frente a c?lulas malignas, conclui-se que os linf?citos TCD8 e as c?lulas NK, estariam atuando no controle da progress?o de neoplasias malignas, mas n?o de forma isolada
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Lima, H?rik Dantas de. "Estudo de um comp?sito Nb-15%pCu obtidos por moagem de alta energia e sinterizados por fase l?quida." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br/handle/123456789/19594.
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Existe uma grande dificuldade na forma??o de um comp?sito do metal refrat?rio de ni?bio com o cobre. Isto se deve ao fato de que o sistema Nb-Cu ? quase mutuamente imisc?vel, podendo ser desprezada a solubilidade entre eles. Estas propriedades dificultam ou impedem a obten??o de estruturas homog?neas e de alta densidade, convencionalmente preparadas. Este trabalho tem por objetivo analisar a utiliza??o do processo de moagem de alta energia (MAE) para transpor estas dificuldades naturais, no que se refere ? densifica??o dos corpos sinterizados. A MAE e a prensagem foram utilizadas na prepara??o dos p?s, para a obten??o de uma fina e homog?nea distribui??o do tamanho dos gr?os. Quatro cargas de p?s de Nb e Cu contendo 15% em massa de Cu foram ent?o mo?dos por MAE em um moinho de bolas tipo planet?rio, sob diferentes per?odos e velocidades de moagem. Os resultados obtidos pela MAE foram analisados atrav?s da microscopia eletr?nica de varredura (MEV), de acordo com os par?metros de tempo e velocidade de moagem. As amostras foram compactadas sob press?o de 200 MPa, em seguida foram sinterizadas por fase l?quida em um forno ? v?cuo nas temperaturas de 1100?C/60 min e 1200?C/60 min. Depois foi utilizada a t?cnica de caracteriza??o de difra??o de raios-X para a identifica??o das fases. As microestruturas das amostras sinterizadas foram observadas e avaliadas atrav?s de microscopia eletr?nica de varredura (MEV). Ensaios de Microdureza Vickers foram realizados, obtendo maiores valores para os corpos sinterizados nos maiores tempos de moagem dos p?s e para as maiores velocidades de moagem. Foi verificado que a sinteriza??o por fase l?quida das amostras que foram processadas por MAE, produziu no final uma estrutura homog?nea e densificada em 77,4% em rela??o ao valor da densidade te?rica do comp?sito
There is great difficulty in forming a composite refractory metal niobium with copper. This is due to the fact that Nb-Cu system is almost mutually immiscible and may be neglected solubility between them. These properties hinder or prevent obtaining homogeneous and high-density structures, conventionally prepared. This study aims to analyze the use of high-energy milling process (MAE) to implement these natural difficulties, with regard to the densification of the sintered bodies. The MAE and the press were used in the preparation of powders, to obtain a fine and homogeneous distribution of the grain size. Four loads Nb and Cu powders containing 15% by weight of Cu were then milled for MAE in a planetary type ball mill under various milling times and speeds. The results obtained by MAE were analyzed by scanning electron microscopy (SEM), according to the parameters of time and grinding speed. The samples were compacted under pressure of 200 MPa, were then sintered in liquid phase in a vacuum furnace at temperatures of 1100 ? C / 60 min and 1200 ? C / 60 min. Then it was used to characterize diffraction of X-rays to identify the phases. The microstructures of the sintered samples were observed and evaluated using scanning electron microscopy (SEM). Vickers Microhardness tests were performed, obtaining higher values for the sintered bodies in the largest of the post milling times and the larger grinding speeds. It was found that the liquid phase sintering of the samples that were processed by MAE produced at the end of a homogeneous and densified structure in 77,4% relative to the value of the theoretical density of the composite
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Oliveira, Samuel Alves de. "Avalia??o cin?tica e potencial do Nb2O5 obtido a partir de um complexo de ni?bio para forma??o do oleato de metila atrav?s da rea??o de esterifica??o do ?cido oleico." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br:8080/jspui/handle/123456789/15854.
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Previous issue date: 2014-01-30Among the heterogeneous catalysts materials made from niobium show up as an alternative to meet the demand of catalysts for biodiesel production. This study aims to evaluate the potential of a heterogeneous catalyst derived from a complex of niobium in the reaction of methyl esterification of oleic acid. The catalyst was synthesized after calcination at different temperatures of a niobium complex ((NH4)3[NbO(C2O4)3].H2O) generating a niobium oxide nanostructure with a different commercial niobium oxide used to synthesize the complex. The commercial niobium oxide, the complex niobium and niobium catalyst were characterized by thermogravimetry (TG and DTA), surface area analysis (BET), scanning electron microscopy (SEM) and X-ray diffraction (XRD), showing the catalyst has researched morphological and crystallographic indicating a catalytic potential higher than that of commercial niobium oxide characteristics. Factorial with central composite design point, with three factors (calcination temperature, molar ratio of alcohol/oleic acid and mass percentage of catalyst) was performed. Noting that the optimal experimental point was given by the complex calcination temperature of 600?C, a molar ratio alcohol/oleic acid of 3.007/1 and the catalyst mass percentage of 7.998%, with a conversion of 22.44% oleic acid in methyl oleate to 60 min of reaction. We performed a composite linear and quadratic regression to determine an optimal statistical point of the reaction, the temperature of calcination of the complex at 450?C, the molar ratio of alcohol/oleic acid 3.3408/1 and mass percentage of catalyst of 7.6833% . Kinetic modeling to estimate parameters for heterogeneous catalysis it set well the experimental results with a final conversion of 85.01% with 42.38% of catalyst and without catalyst at 240 min reaction was performed. Allowing to evaluate the catalyst catalytic studied has the potential to be used in biodiesel production
Dentre os catalisadores heterog?neos os materiais a base de ni?bio mostram-se como uma alternativa para suprir a demanda de catalisadores para a produ??o de biodiesel. O presente trabalho visa avaliar o potencial de um catalisador heterog?neo derivado de um complexo de ni?bio na rea??o de esterifica??o met?lica do ?cido oleico. O catalisador foi sintetizado ap?s a calcina??o em diferentes temperaturas de um complexo de ni?bio ((NH4)3[NbO(C2O4)3].H2O) gerando um ?xido de ni?bio com uma nanoestrutura diferente do ?xido de ni?bio comercial, usado para sintetizar o complexo. O ?xido de ni?bio comercial, o complexo de ni?bio e o catalisador de ni?bio foram caracterizados por termogravimetria (TG e DTA), an?lise de ?rea superficial (BET), microscopia eletr?nica de varredura (MEV) e difra??o de raios-X (DRX), demostrando que o catalisador pesquisado possui caracter?sticas morfol?gicas e cristalogr?ficas que indicam um potencial catal?tico superior ao ?xido de ni?bio comercial. Foi realizado um planejamento fatorial composto com ponto central, com tr?s fatores (temperatura de calcina??o, raz?o molar de ?lcool/?cido oleico e percentual m?ssico de catalisador). Verificando que o ponto ?timo experimental se deu mediante a temperatura de calcina??o do complexo em 600?C, uma raz?o molar de ?lcool/?cido oleico de 3,007/1 e percentual m?ssico de catalisador de 7,998%, apresentando uma convers?o de 22,44% do ?cido oleico em oleato de metila em 60 min de rea??o. Realizou-se uma regress?o linear e quadr?tica composta para se determinar de um ponto ?timo estat?stico da rea??o, sendo a temperatura de calcina??o do complexo em 450?C, raz?o molar de ?lcool/?cido oleico de 3,3408/1 e percentual m?ssico de catalisador de 7,6833%. Foi realizada uma modelagem cin?tica para estima??o de par?metros para a cat?lise heterog?nea que se ajustou satisfatoriamente aos resultados experimentais com uma convers?o final de 85,01% com catalisador e de 42,38% sem o catalisador em 240 min de rea??o. Permitindo avaliar que o catalisador estudado possui potencial catal?tico para ser utilizado na produ??o de biodiesel
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Asses, Yasmine. "Conception par modélisation et criblage in silico d'inhibiteurs du récepteur c-Met." Phd thesis, Université Henri Poincaré - Nancy I, 2011. http://tel.archives-ouvertes.fr/tel-00653609.
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L'enjeu des travaux effectués au cours de cette thèse est l'extraction in silico de molécules potentiellement intéressantes dans le processus d'inhibition du récepteur tyrosine kinase c-Met. La faculté de cette protéine à interagir dans les phénomènes d'embryogenèse et de réparation tissulaires rendent son inhibition cruciale dans les traitements contre les développements tumoraux où c-Met se trouve impliquée. Dans ce but, la stratégie que nous avons employée implique l'utilisation de plusieurs méthodes in silico de conception rationnelle de médicaments. Nous avons utilisé comme support les multiples structures cristallographiques publiées sur la ProteinData Base (PDB). Un travail de modélisation par homologie fut tout d'abord nécessaire pour combler les lacunes des structures cristallographiques collectées. Afin d'échantillonner au mieux l'espace conformationnel du récepteur kinase c-Met et de caractériser sa flexibilité, une longue campagne de simulation de Dynamique Moléculaire (DM) fut menée concernant les formes apo et holo des structures cristallographiques disponibles. Pour compléter ces simulations, une partie du travail consista à utiliser également la méthode des modes normaux de vibration (NM). De ces 2 approches (DM et NM), nous avons extrait un ensemble de 10 conformères considérés comme les plus représentatifs de l'espace conformationnel simulé pour la kinase c-Met et avons proposé un mode de fonctionnement de ce récepteur. Utilisant les conformations extraites de l'échantillonnage conformationnel, nous avons ensuite mené une importante campagne de criblage virtuel sur plusieurs chimiothèques constituant au total environ 70.000 composés. L'analyse des résultats de l'arrimage moléculaire nous a conduits à la sélection de plusieurs molécules intéressantes possédant théoriquement une bonne affinité pour la kinase c-Met. Ces molécules ont été soumises aux tests expérimentaux effectués par l'équipe de biologistes associée à nos travaux.
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Silveira, Ericka Janine Dantas da. "Perfil imuno-histoqu?mico do infiltrado inflamat?rio no front de invas?o em carcicomas epiderm?ides de l?ngua e l?bio inferior." Universidade Federal do Rio Grande do Norte, 2007. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17168.
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Previous issue date: 2007-03-09Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
The progression of the oral squamous cells carcinomas (OSCCs) seems to suffer influence from related factors to the host, as local and systemic immunologic response, which are essential to the antineoplasic defenses. The purpose of this study was evaluate the local immunity in 30 tongue and 20 lower lip SCC by immunohistochemistry method, utilizing antibodies anti-CD3, CD4, -CD8, -CD25 e -ζ(zeta), which immunoexpressions were compared considering the anatomical localization, the intensity of the inflammatory infiltrate into the front of invasion and metastases. The CD4/CD8+ ratio was calculated for each case and associate with the mentioned variable, being the intensity of the inflammatory infiltrated also compared with the anatomical localization and metastase and for this the cases had been grouped in two categories: (n = 10) absent/scarce inflammatory infiltrate; and (n = 40) moderate/intense infiltrate. Fisher?s exact test was performed (α= 0.05) and it was not observed any significant correlation between these groups with anatomical sites and metastases. With regard to the immunoexpression, the CD3+, CD4+, CD8+ and CD25+ cells count was higher in the lower lip SCCs while the anti-ζimmunomarcation was more evident in the non metastatic cases. Through the statistical analyses, it was verified that the CD3 exhibited positive-significant correlation with the inflammatory infiltrate (p = 0.023). Furthermore, antibodies against CD8 and CD25 cells were also significantly correlated with the inflammatory infiltrate (p = 0.002 and 0.030, respectively) and with the anatomical site (p = 0.004 and p = 0.004) mainly in the lower lip SCCs. CD4/CD8 ratio did not show significant association with metastase nor with anatomical localization. We conclude that the inflammatory infiltrated of the Bryne s (1998) system did not constitute an indicator of aggressiveness in the tongue and lower lip SCCs analyzed and that clinical behavior of the SCCs studied was related in part to the immunohistochemical profile of infiltrated the inflammatory present in tumoral invasion front
A progress?o dos carcinomas epiderm?ides orais (CEOs) parece sofrer influ?ncia de fatores relacionados ao hospedeiro, como a resposta imunol?gica local e sist?mica, as quais parecem ser essenciais para a defesa anti-neopl?sica. O presente estudo teve por objetivo analisar a imunidade local em 30 casos de CEs de l?ngua e 20 de l?bio inferior, atrav?s do m?todo da imuno-histoqu?mica, utilizando os anticorpos anti-CD3, -CD4, -CD8, -CD25 e -ζ(zeta), comparando a imunomarca??o em ambas as localiza??es, com a intensidade de infiltrado inflamat?rio no front de invas?o e com presen?a ou n?o de met?stase. A raz?o de c?lulas CD4/CD8+ foi calculada para cada caso e associada com as vari?veis mencionadas, sendo a intensidade do infiltrado inflamat?rio comparada tamb?m com a localiza??o anat?mica e met?stase e para isso os casos foram agrupados em duas categorias (infiltrado escasso ou ausente E/A e infiltrado intenso ou moderado I/M), sendo encontrado 10 casos na categoria E/A e 40 na categoria I/M. Aplicado o teste exato de Fisher n?o verificamos associa??o significativa destes grupos com o s?tio anat?mico ou com met?stase. Em rela??o ? imunomarca??o, a contagem das c?lulas CD3+, CD4+, CD8+ e CD25+ foi maior nos CEs de l?bio inferior e sem met?stase, enquanto que o anti-ζfoi mais expresso apenas nos casos sem met?stase. Atrav?s da an?lise estat?stica verificou-se que os anticorpos anti-CD3, anti-CD8 e anti-CD25 exibiram associa??o significativa positiva com o infiltrado inflamat?rio (p=0.023, p=0.002 e p=0.030, respectivamente); e os anticorpos anti-CD8 a anti-CD25 estiveram associados de forma positiva com a localiza??o anat?mica, ambos com valores de p=0.004, estando estes mais presentes nos CEs de l?bio inferior. A raz?o CD4/CD8 n?o exibiu associa??o significativa com met?stase nem com localiza??o anat?mica. Conclu?mos que o padr?o infiltrado inflamat?rio da grada??o histol?gica de malignidade de Bryne (1998) n?o constituiu um indicador de agressividade nos CEs de l?ngua e l?bio inferior analisados, e que o comportamento cl?nico dos CEs estudados esteve relacionado em parte ao perfil imuno-histoqu?mico do infiltrado inflamat?rio presente no front de invas?o tumoral
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Lima, Camila Diana. "S?ntese de ?steres met?licos de ?cidos graxos (biodiesel) e de ?steres benz?licos por rea??o qu?mica com catalisadores heterog?neos baseados em NbCl5 e SiO2-Nb." UFVJM, 2017. http://acervo.ufvjm.edu.br/jspui/handle/1/1370.
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O presente trabalho descreve o estudo de novas metodologias para obten??o de ?steres benz?licos e ?steres met?licos de ?cidos graxos (biodiesel) utilizando o NbCl5 s?lido e catalisadores heterog?neos ?cidos. No estudo, o NbCl5 s?lido foi utilizado como reagente, e nos outros m?todos foi empregado um catalisador de ni?bio enxertado em s?lica e um catalisador de grupos sulf?nicos imobilizado em s?lica. Nos processos heterog?neos a SiO2 (507 m2g-1, ?rea espec?fica) utilizada como suporte dos catalisadores, foi produzida a partir de areia constru??o e carbonato. O NbCl5 e os grupos ?SO3H foram imobilizados diretamente ? temperatura ambiente na SiO2, formando respectivamente o SiO2-Nb, com 412 m2g-1 de ?rea espec?fica e o SiO2-SO3H, com 115 m2g-1 de ?rea espec?fica. Nas esterifica??es utilizando NbCl5 s?lido foi determinado que para a obten??o de rendimentos razo?veis de ?steres de benz?licos (>85%) e ?steres met?licos (>70%) em rea??es a temperatura ambiente, a propor??o m?nima em moles de NbCl5:?lcool benz?lico deve ser 1,5:1,0 e para obten??o dos ?steres met?licos a propor??o de 1,5:6,0. Nas metodologias aplicando os catalisadores heterog?neos foi utilizada uma quantidade de 7% (m/m) do catalisador SiO2-SO3H para catalisar a esterifica??o de diferentes ?cidos carbox?licos com ?lcool benz?lico. E para as mesmas rea??es com o catalisador SiO2-Nb foi utilizada uma raz?o de 10% (m/m) do catalisador. Ambos os processos foram realizados sob refluxo na aus?ncia de um solvente; rendimentos muito semelhantes foram obtidos apesar do catalisador SiO2-SO3H possuir uma ?rea superficial muito menor que o catalisador SiO2-Nb.
Disserta??o (Mestrado) ? Programa de P?s-gradua??o em Biocombust?veis, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2017.
The current work describes the study of new methodologies for obtaining benzyl esters and methyl esters of fatty acids (biodiesel) using solid NbCl5 and heterogeneous acid catalysts. In this study, solid NbCl5 was used as a reagent, and in the other methods a silica grafted niobium catalyst and a sulphonic group catalyst immobilized on silica were used. In the heterogeneous processes the SiO2 (507 m2g-1, specific area) used as support of the catalysts, was produced from sand building and carbonate. The NbCl5 and the -SO3H groups were directly immobilized at room temperature in SiO2, forming respectively SiO2-Nb, with 412 m2g-1 of specific area and SiO2 -SO3H, with 115 m2g-1 of specific area. In the esterifications using solid NbCl5 it was determined that in order to obtain reasonable yields of benzyl esters (>85%) and methyl esters (>70%) in reactions at room temperature, the minimum mole ratio of NbCl5/benzyl alcohol should be 1,5:1,0 and in the obtainment of the methyl esters at a ratio of 1,5:6,0. In the methodologies applying the heterogeneous catalysts to an amount of 7% (w/w) of the catalyst SiO2 -SO3H to catalyze an esterification of different carboxylic acids with benzyl alcohol. Both processes were performed under reflux in the absence of a solvent; very similar yields were obtained although the SiO2-SO3H catalyst had a much lower surface area than the SiO2-Nb catalyst.
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Bellander, Ylva. "Återanvändning av sulfidförande berg : Aktuellt kunskapsläge, statistisk analys och biotillgänglighetsmodellering." Thesis, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-444793.
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Sulfidförande berg förekommer på många platser i Sveriges berggrund. När sulfidförande berg losshålls frigörs nya ytor som utsätts för kontakt med syre och vatten, vilket oxiderar sulfidmineralen och berget vittrar. Vittringsprodukten kallas surt lakvatten. Syftet med arbetet har varit att undersöka hur det sura lakvattnet påverkar den omgivande miljön, och hur spridning av det kan förhindras, samt vilka teoretiska möjligheter och risker det finns för användning av sulfidförande berg i infrastrukturprojekt. När lakvattnet kommer i kontakt med omkringliggande vattendrag orsakar det försurning och förhöjda metallhalter. Det kan också orsaka geotekniska skador. För att på ett säkert sätt kunna återanvända bergmaterialet bör provtagning och provanalys utföras enligt representativa metoder och bedömning av omgivningens förutsättningar ske. De metoder som idag används är i stor grad utvecklade för gruvnäringen och behöver därför anpassas. Om materialet bedöms lämpligt för återanvändning eller om sulfidbärande bergmaterial oavsiktligt använts finns en mängd metoder för att minska negativ påverkan på omgivningen. Mest effektivt är förhindrande av bildning av lakvatten genom övertäckning eller mikroinkapsling. Det finns även metoder för att förhindra spridning av surt lakvatten, såsom kalkning eller olika typer av barriärer eller dräneringsbäddar. För att det losshållna berget ska kunna återanvändas behöver hänsyn tas till en mängd olika lagar och regler. Inom ramen på projektet utfördes en fallstudie av ett område där sulfidförande berg losshållits och oavsiktligt använts som fyllnadsmaterial i lokala vägar. Detta har lett till att vattendraget som rinner genom området kraftigt förorenats med metaller och på vissa platser har mycket låga pH-värden. Sex metaller (Cd, Co, Cu, Ni, Pb and Zn) och sex andra parametrar (pH, Fe, fosfat, nitrat, sulfat och DOC) valdes ut för korrelationsanalys mellan metallerna och parametrarna med Kendall's Tau i fyra olika provpunkter. Statistiskt säkerställda korrelationer förekom mellan samtliga metaller och parametrar, men inte i alla punkter. Korrelationerna med pH och DOC var starkast, men även korrelationer med järn, fosfat och sulfat förekom enligt förväntan. Korrelationer med nitrat förekom med samtliga metaller men med oregelbundenhet och utan mönster. Biotillgänglighetsmodellering med verktyget bio-met utfördes för Cu, Ni, Pb och Zn. Biotillgängligheten var starkast relaterad till DOC-halten, men även samband med pH kunde statistiskt säkerställas. Ni och Zn var de metaller med högst biotillgänglighet. I vissa fall översteg den biotillgängliga koncentrationen HC5, gränsvärdet för skydd av 95 % av organismerna i vattendraget. I flera av punkterna över- eller underskred pH och kalciumhalten modellens godkända intervall. En utveckling av modellen för inkludering av fler förutsättningar och metaller är därför något att eftersträva.Sulfide-bering rock is found in multiple places in Swedish bedrock. When blasted, new surfaces is exposed and weathering occurs. This has the consequence that Acid Rock Drainage (ARD), water with low pH and high concentrations of heavy metals is spread to local watercourses, the environment becomes toxic. The aim of this project was to investigate theoretical possibilities and risks with recycling of sulfide-bering rock in infrastructure projects, as well as to examine how ARD affects the surrounding environment and how spreading of ARD can be prevented. To safely recycle the rock, it needs to be sampled and analysed by proper methods and the conditions of the sorrounding environment evaluated. Methods for applying this in infrastructure projects is currently being developed. If used, there is multiple methods to prevent or mitigate the spreading of ARD. The most effective way is to prevent its forming by covering or microencapsling, but prevention of spreading can also be dealt with by liming or drainage beds. A case study was made of an area affected by ARD. Correlation analysis with Kendall's tau was conducted between six metals (Cd, Co, Cu, Ni, Pb and Zn) and six other parameters (pH, Fe, phosphate, nitrate, sulphate and DOC). The correlations between the metals and pH as well as DOC was the stongest. It was difficult to find a pattern in the correlations with nitrate. Bioavailability modelling with the Biotic Ligand model bio-met was also made. Ni and Zn hade the highest bioavailable concentrations and exceeded the limit for protection of 95 % of species in one (Zn) or two (Ni) measuring stations. Expanded models for bioavailability is needed, since they have narrow boundaries for water chemistry conditions and only exist for few metals.
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Joubert, Karen. "Rol van die ouers by die kontinue insluiting van leerders met Downsindroom in inklusiewe onderwys in Gauteng." Diss., 2012. http://hdl.handle.net/10500/7665.
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Text in AfrikaansThe purpose of this study is to identify the role of the parents in the continuous inclusion of learners with Down’s syndrome in inclusive education. The study was conducted in the South African context with the parents of children with Down’s syndrome and who are currently included in inclusive education in Gauteng. The roles that these parents play in the inclusion of their children were identified by means of semi-structured interviews. This was done according to a qualitative phenomenological research design within the theoretical framework of the bio-ecological model of Brunfenbrenner. Results from this study indicated that parents will have to fulfil specific roles in a multi-faceted manner to ensure continuous inclusion for these learners with Down’s syndrome in inclusive education. The primary contribution of this study is towards the expansion of the theoretical knowledge of the role of the parents in continuous inclusive education of learners with Down’s syndrome.
Die doel van hierdie studie is om die ouers se rol by die kontinue insluiting van leerders met Downsindroom in inklusieweonderwys te bepaal. Die studie is binne die Suid-Afrikaanse milieu onderneem met die ouers van leerders met Downsindroom wat tans gewone inklusieweonderwys in Gauteng ontvang. Semi-gestruktureerdeonderhoude is gebruik om die ouers se rol in die kontinue insluiting van hul kinders in gewone inklusiewe onderwys te identifiseer. Hierdie studie is volgens’n kwantitatiewefenomenologiesenavorsingsontwerp binne die teoretiese raamwerk van die bio-ekosistemiesebenaderingsmodel van Bronfenbrenner uitgevoer.Die bevindings van hierdie studie toon dat ouers spesifieke rolle behoort te vervul om hierdie leerders se kontinue insluiting in inklusiewe onderwys te verseker. Die primêre bydrae wat hierdie studie sal lewer, is tot die uitbreiding van teoretiese kennis aangaande die ouers se rol in die insluiting van leerders met Downsindroom in inklusiewe onderwys.
Inclusive Education
M. Ed. (Inklusiewe Onderwys)
Books on the topic "Bio-met"
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van, Bork G. J., and Verkruijsse P. J, eds. De Nederlandse en Vlaamse auteurs: Van middeleeuwen tot heden met inbegrip van de Friese auteurs. Weesp: De Haan, 1985.
Find full textBook chapters on the topic "Bio-met"
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Zondag, W., and M. V. Huisman. "Is antistolling met een vitamine-K-antagonist bij een bio-hartklepprothese overbodig?" In Vademecum permanente nascholing huisartsen, 1912–13. Houten: Bohn Stafleu van Loghum, 2006. http://dx.doi.org/10.1007/978-90-313-8808-0_1024.
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Gonçalves-Pereira, Manuel, and António Leuschner. "Portugal." In Dementia Care: International Perspectives, 219–30. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198796046.003.0029.
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Dementia care in Portugal presents a mixed balance of strengths and important problems and challenges. This chapter begins by highlighting the scarcity of health service data on dementia, within a rapidly changing and complex array of health and social care systems. Public, private, and third-sector services are not integrated enough to fully meet the needs of people with dementia and their families. Despite examples of good standards in dementia care, some complex challenges still need tackling. Portugal does not have a National Dementia Plan, although formal efforts are being made and a general strategy has been proposed. The chapter briefly discusses leading issues, while highlighting that any selection of goals and the feasibility of achieving them are constrained by a shortage of resources. Taking the need to improve timely diagnosis and integrated formal services as an example, the exact role of primary care is one of the primary topics for discussion. In short, there are three aspects which Portugal does well in terms of dementia care: (1) every person with dementia has access to emergency services and, in principle, to primary care services within the public National Health Service; (2) there are examples of high-quality standards in clinical dementia care, mainly in urban centres, and an increasing interest from the social sector, non-governmental organizations, and private institutions in community or institutional social care; and (3) there is increasing interest in dementia-related service research, as well as in psycho-geriatric training. For the future, first, primary care should be more involved in early diagnosis of dementia and its appropriate disclosure, as well as in other areas, e.g. treatment monitoring in collaboration with specialized care, counselling and support, and monitoring caregivers’ health. Second, the complex bio-psycho-social needs in dementia should be better met through improvement of: timely access to community formal services or specialized accommodation when necessary; ‘dementia-friendly’ communities and health/social units (e.g. general hospitals, given the multimorbidity in people with dementia); management of behavioural and psychological symptoms of dementia (with more emphasis on non-pharmacological approaches, and less on antipsychotics); informal caregivers’ support, ensuring minimum standards of information, counselling, psycho-education, and other family interventions; and legal procedures, access to new technologies, and decent end-of-life care. Finally, gaps should be bridged between health and social care, fostering care coordination and case management in every phase of dementia (with standardization of dementia care processes, e.g. definition of the roles of professionals).
Conference papers on the topic "Bio-met"
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Zielinski, Oliver, Barbara Cembella, and Ru¨diger Heuermann. "Bio-Optical Sensors Onboard Autonomous Profiling Floats." In 25th International Conference on Offshore Mechanics and Arctic Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/omae2006-92482.
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The perspective of an array of thousands of floats drifting in the world ocean offers the possibility to monitor global ocean currents via the distribution of oceanographic parameters like temperature and salinity (WOCE – ARGO programme). Deploying these floats with advanced bio-optical sensors for the detection of bio-geochemical parameters offers a potential for large scale assessment of the pelagic primary productivity and the bio-geochemical processes involved. Technical specifications to be met by these sensors will be: low power consumption, long-term stability and reliability, standardized interfaces and protocols together with an intelligent data handling. However, these requirements also demand sophisticated capabilities of the float as a platform. Enhanced interfaces, algorithmic power and memory including new telemetry and docking solutions are necessary to provide a flexible and yet reliable platform for bio-geochemical sensors onboard floats. Within this work an overview of bio-optical sensors, which were integrated in autonomous profiling systems, will be given. This introduction will be followed by first results from hyperspectral irradiance and radiance data from the Navigating European Marine Observer (NEMO) float which were obtain during a two-day lake experiment. Finally, future integrations of sensors and general requirements for floating profiling drifter in the context of coastal and open ocean observatories will be discussed.
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Gunn, Ben, Panagiotis Alevras, and Stephanos Theodossiades. "Energy Harvesting From Torsional Vibrations Using a Nonlinear Oscillator." In ASME 2016 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/detc2016-59467.
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Harvesting ambient energy in a variety of systems and applications is a relatively recent trend, often referred to as Energy Harvesting. This can be typically achieved by harvesting energy (that would otherwise get wasted) through a physical process aiming to convert energy amounts to useful electrical energy. The harvested energy can be thermal, solar, wind, wave or kinetic energy, with the last class mainly referring to harvesting energy from vibrating components or structures. More often these oscillations are error states from the systems’ ideal function and through harvesting this potentially wasted energy could be reclaimed and become useful. Regardless of the generally low power output of the devices designed to harvest energy from vibrations, their use remains an attractive concept, which is mostly attributed to the growing use of modern electronic devices that exploit the low power requirements of semi-conductors. Energy Harvesting applications are often met in situations where a network of essential electronic devices, such as sensors in Structural Health Monitoring or bio-implantable devices, becomes hardly accessible. Harvesting ambient vibrations to power up these devices offers the option to utilize wireless sensors rendering these systems autonomous. Typical cases of systems, where ambient vibrations are ubiquitous are met in automotive and aerospace applications. Besides their potentially adverse impact, the energy carried by vibrating parts could be harvested, such that wireless sensors are powered. In this paper, a concept for harvesting torsional vibrations is proposed, based on a concept that employs magnetic levitation to establish a nonlinear Energy Harvester. Experience has shown that linear harvesters require resonant response to operate, often leading to low performance of the device when the excitation frequency deviates from resonance conditions. This is why harvesters with essential nonlinearity are preferred, since they are able to demonstrate high response levels over wider frequency regions. Herein, the conducted study aims to demonstrate the functionality of this concept for torsional systems. A mathematical model of the coupled nonlinear electromechanical system is established, seeking preliminary estimates of the harvested power. The compelling attribute of this system lies in the dependency of its linear natural frequency on the excitation frequency, which is found to cause multiple response peaks in the corresponding frequency spectra. Moreover, the selection of the static equilibrium of the levitating magnet is found to greatly influence the system’s response.
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Teets, Jon W., and J. Michael Teets. "A 150Kw Integrated Solar Combined Cycle (ISCC) Power Plant." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-69020.
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With the soaring price of oil and the global push toward reduction in carbon emissions, renewable energy is treated by many as a solution to the economic and environmental cost of consumption of fossil fuels. With the power plant reviewed in this paper use of Solar and Bio-fuels will be attained. During the day power needs can be met with Solar energy and when that energy supply is not adequate can use bio-fuels or fuel of choice (gaseous or liquid). If there is a need for use only with Solar energy (i.e. peak power demand) can shut down and restart when desired. Due to the size of the unit, start up is not a long labor intensive task and can be accomplished within the hour. The 150 Kw Integrated Solar Combined Cycle (ISCC) power plant is for commercial and residential use. The unit will produce 150 Kw electrical power output to customer with Solar Thermal Energy (STE). Solar Thermal energy is attained from parabolic trough concentrator(s). Working fluid in the STE system is Syltherm 800 (Silicone Heat Transfer Fluid) is acceptable use from –40F to 750 F. This fluid is heated and passes through a heat exchanger to transfer energy to the closed rankine cycle (where the liquid is changed to vapor stage. Steady state analysis performed on the rankine cycle, with ammonia / water mixture (50/50) used NIST standard reference database 23 for the thermodynamic and transport properties REFPROP [1]. A unique feature with the combined cycle unit, is the rankine cycle turbine wheel is directly attached to the power producing gas turbine spool, thus share a common high speed permanent magnet alternator assembly. The core gas turbine engine used in the combined cycle is a two spool, high pressure ratio (11:1) simple cycle microturbine with cycle efficiency of 20%, at 70Kw output electrical power (sea level standard day). The latter is defined as model TMA 70SC. In addition to the gas turbine engine and rankine turbine stage, the combined cycle incorporates a gas turbine waste heat boiler, economizer, condenser and economizer fluid preheater. The combined cycle unit, without thermal energy, will produce 145Kw (sea level standard day) with an electrical output efficiency of 40%. The gas turbine exhaust to atmosphere will be less than 240 F. The ISCC unit power producing spool / rotor will operate at 100% N regardless of gas turbine power demand. Whereas, spool number one will vary with gas turbine power demand. When the available solar thermal energy decreases the gas turbine fuel flow will increase to maintain electrical power, pending day conditions. The ISCC power plant, can be used for main power plants in [stand alone] communities, business, industrial or distributed energy (D.E.). Also, will provide electrical power to the customer at lower rate than traditional power companies.