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1

TÖrmälä, P., T. Pohjonen, and P. Rokkanen. "Bioabsorbable polymers: Materials technology and surgical applications." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 212, no. 2 (1998): 101–11. http://dx.doi.org/10.1243/0954411981533872.

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Biostable and bioabsorbable biomaterials are used to manufacture implants for supporting, replacement, augmentation and guiding of growth of tissues. Bioabsorbable implants are a better choice for applications where only the temporary presence of the implant is needed. Because of bioabsorption of such implants, there is no need for a removal operation after healing of the tissue and the risks of implant related, long-term complications are eliminated or strongly reduced. Reinforcing of bioabsorbable materials is necessary in order to develop strong and safe, small implants for fixation of bone
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2

Reznik, L. B., V. V. Guryev, M. A. Turushev, D. A. Negrov, and R. E. Il’in. "Avulsion Fractures Osteosynthesis in Patients with Normal Bone Mineral Density and Osteoporosis." Traumatology and Orthopedics of Russia 24, no. 4 (2018): 72–80. http://dx.doi.org/10.21823/2311-2905-2018-24-4-72-80.

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Objective:to compare the effectiveness of osteosynthesis for avulsion fractures using bioabsorbable versus titanium implants in patients differing in bone mineral density.Material and Methods.In the experimental phase of study, two groups of bone blocks were singled out from patients' femoral heads to assess the anchoring properties of the implant in osteoporotic and healthy bone. The first group included blocks of 31 patients with osteoporosis, the second one — 27 blocks of patients without osteoporosis. In the first group, cortical bioabsorbable Poly-L-Lactic/ co-glycolic acid (PLGA) screws
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Hagelstein, Salome, Michael Seidenstuecker, Adalbert Kovacs, Roland Barkhoff, and Sergej Zankovic. "Fixation Performance of Bioabsorbable Zn-6Ag Pins for Osteosynthesis." Materials 15, no. 9 (2022): 3280. http://dx.doi.org/10.3390/ma15093280.

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Bioabsorbable implants have become the focus of the latest research for new bone implant materials. With favorable characteristics such as compatible mechanical characteristics, no long-term side effects, and even osteogenesis enhancing properties they seem to be the future of osteosynthesis. Besides these characteristics, they must perform on the same level as traditional implant materials regarding their mechanical support for bone healing. A particular focus in the research for bioabsorbable implants has been on metal alloys, as these have particularly good mechanical properties such as exc
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Patton, C. S., R. F. McConnel, R. Ross, G. M. H. Shires, and Nancy Korenek. "A Bioabsorbable Polymer for Collateral Ligament Repair in the Pig." Veterinary and Comparative Orthopaedics and Traumatology 05, no. 02 (1992): 80–84. http://dx.doi.org/10.1055/s-0038-1633072.

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SummaryA bioabsorbable internal fixation device of a poly-L-isomer of lactic acid (PLLA) was used to repair the proximal attachment of the medial femorotibial collateral ligament (MCL) in six miniature Yucatan pigs and compared with metal screw fixation in four pigs. Healing was evaluated by physical examination, gross dissection of surgical sites and histological evaluation of bone ligament interface. Chemical stress analysis of the tack was also evaluated.The absorbable PLLA tack induced minimal tissue reaction and maintained sufficient apposition for healing of the MCL in the miniature Yuca
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Minocha, Dr. Pramod Kumar, Deveshkumar Mahendralal Kothwala, and Niravkumar Maheshbhai Rana. "Development of a Bioresorbable Implant for Nasal Valve Collapse." International Journal Of Medical Science And Clinical Research Studies 02, no. 09 (2022): 928–34. https://doi.org/10.5281/zenodo.7067023.

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The aim of the present study is to report outcomes after treatment of nasal valve collapse with a bioabsorbable nasal implant. Nasal obstruction is a main occurrence of breathing difficulties, with lateral wall insufficiency (LWI) playing a crucial role. A bioabsorbable nasal implant was recently introduced to treat nasal blockage and rectify lateral wall insufficiency. In this study, a systematic review and meta-analysis were conducted to investigate bioabsorbable nasal implant efficacy in treating nasal obstruction following reconstructive or rehabilitation surgery. A bioresorbable nasal imp
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Maurus, Peter B., and Christopher C. Kaeding. "Bioabsorbable implant material review." Operative Techniques in Sports Medicine 12, no. 3 (2004): 158–60. http://dx.doi.org/10.1053/j.otsm.2004.07.015.

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Vaccaro, Alexander R., and Luke Madigan. "Spinal applications of bioabsorbable implants." Journal of Neurosurgery: Spine 97, no. 4 (2002): 407–12. http://dx.doi.org/10.3171/spi.2002.97.4.0407.

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✓ With the increasing use of bioabsorbable implants in a variety of clinical conditions, potential advantages in selected spinal applications are now being realized. Newer polymers with biomechanical properties relevant to the requirements of specific spinal implants and resorption rates appropriate for specific spinal applications are being developed. These new materials offer the necessary biomechanical stability of conventional spinal implants without the sequelae associated with metallic implants such as long-term loosening, implant migration, and imaging interference. At this time, the ma
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Robbins, Matthew M., Alexander R. Vaccaro, and Luke Madigan. "The use of bioabsorbable implants in spine surgery." Neurosurgical Focus 16, no. 3 (2004): 1–7. http://dx.doi.org/10.3171/foc.2004.16.3.2.

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The use of bioabsorbable implants in spine surgery is expanding at a rapid pace. These implants are mimicking the roles of traditional metallic devices and are demonstrating similar efficacy in terms of maintaining stability and acting as carriers for grafting substances. Biomechanical studies have demonstrated their ability to stabilize effectively a degenerative cervical and lumbar motion segment. In numerous animal models, researchers have illustrated the ability of bioabsorbable implants to function satisfactorily as an interbody spacer and to achieve satisfactory bone fusion. Investigator
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Rousselle, Serge D., Yuval Ramot, Abraham Nyska, and Nicolette D. Jackson. "Pathology of Bioabsorbable Implants in Preclinical Studies." Toxicologic Pathology 47, no. 3 (2019): 358–78. http://dx.doi.org/10.1177/0192623318816681.

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Bioabsorbable implants can be advantageous for certain surgical tissue bioengineering applications and implant-assisted tissue repair. They offer the obvious benefits of nonpermanence and eventual restoration of the native tissue’s biomechanical and immunological properties, while providing a structural scaffold for healing and a route for additional therapies (i.e., drug elution). They present unique developmental, imaging, and histopathological challenges in the conduct of preclinical animal studies and in interpretation of pathology data. The bioabsorption process is typically associated wi
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Kawamura, Naohiko, Yuya Nakao, Rina Ishikawa, Dai Tsuchida, and Masahiro Iijima. "Degradation and Biocompatibility of AZ31 Magnesium Alloy Implants In Vitro and In Vivo: A Micro-Computed Tomography Study in Rats." Materials 13, no. 2 (2020): 473. http://dx.doi.org/10.3390/ma13020473.

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In current orthodontic practice, miniscrew implants (MSIs) for anchorage and bone fixation plates (BFPs) for surgical orthodontic treatment are commonly used. MSIs and BFPs that are made of bioabsorbable material would avoid the need for removal surgery. We investigated the mechanical, degradation and osseointegration properties and the bone-implant interface strength of the AZ31 bioabsorbable magnesium alloy to assess its suitability for MSIs and BFPs. The mechanical properties of a Ti alloy (TiA), AZ31 Mg alloy (MgA), pure Mg and poly-L-lactic acid (PLA) were investigated using a nanoindenta
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Medina, Giovanna, Guilherme Garofo, Caio O. D’Elia, Alexandre C. Bitar, Wagner Castropil, and Breno Schor. "Bioabsorbable Suture Anchor Migration to the Acromioclavicular Joint: How Far Can These Implants Go?" Case Reports in Orthopedics 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/834896.

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Few complications regarding the use of bioabsorbable suture anchors in the shoulder have been reported. What motivated this case report was the unusual location of the anchor, found in the acromioclavicular joint which, to our knowledge, has never been reported so far. A 53-year old male with previous rotator cuff (RC) repair using bioabsorbable suture anchors presented with pain and weakness after 2 years of surgery. A suspicion of retear of the RC led to request of a magnetic resonance image, in which the implant was found located in the acromioclavicular joint. The complications reported wi
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Mullen, Michael J., Carol A. Devellian, and Christian Jux. "BioSTAR®bioabsorbable septal repair implant." Expert Review of Medical Devices 4, no. 6 (2007): 781–92. http://dx.doi.org/10.1586/17434440.4.6.781.

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Roesner, Maria, Sergej Zankovic, Adalbert Kovacs, Moritz Benner, Roland Barkhoff, and Michael Seidenstuecker. "Mechanical Properties and Corrosion Rate of ZnAg3 as a Novel Bioabsorbable Material for Osteosynthesis." Journal of Functional Biomaterials 15, no. 2 (2024): 28. http://dx.doi.org/10.3390/jfb15020028.

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Osteosynthesis in fracture treatment typically uses hardware that remains in the patient’s body, which brings a permanent risk of negative side effects such as foreign body reactions or chronic inflammation. Bioabsorbable materials, however, can degrade and slowly be replaced by autologous bone tissue. A suitable material is requested to offer great biocompatibility alongside excellent mechanical properties and a reasonable corrosion rate. Zinc–silver alloys provide these characteristics, which makes them a promising candidate for research. This study investigated the aptitude as a bioabsorbab
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Nguyen, Shawn, Katie L. Fletcher, and John A. Schlechter. "OUTCOMES OF BIOABSORBABLE FIXATION OF OSTEOCHONDRAL INJURIES IN THE PEDIATRIC AND ADOLESCENT KNEE." Orthopaedic Journal of Sports Medicine 7, no. 3_suppl (2019): 2325967119S0017. http://dx.doi.org/10.1177/2325967119s00172.

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Background: Osteochondral lesions (OCL), including osteochondritis dissecans (OCD) and traumatic osteochondral fractures (OCF), are often encountered when treating injuries affecting the pediatric and adolescent knee. There are an array of treatment options depending upon lesion size, location, chronicity, and equally important, surgeon experience. There is a potential for healing in children and adolescents that may not be present in adults and the intent of internal fixation is to reduce and restore the injured hyaline cartilage and underlying bone. Stable fixation utilizing bioabsorbable im
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15

Vaccaro, Alexander R., Matthew M. Robbins, Luke Madigan, Todd J. Albert, William Smith, and Alan S. Hilibrand. "Early findings in a pilot study of anterior cervical fusion in which bioabsorbable interbody spacers were used." Neurosurgical Focus 16, no. 3 (2004): 1–5. http://dx.doi.org/10.3171/foc.2004.16.3.8.

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Object In this pilot study the authors assessed the efficacy of bioabsorbable interbody spacers in the treatment of cervical degenerative disease. Metallic cages or interbody spacers have been widely used in the treatment of degenerative and traumatic cervical disease. Bioabsorbable technology has been used to develop a resorbable cage that can eliminate the complications and drawbacks seen with the use of traditional metallic implants. In general clinical practice bioabsorbable implants have shown the ability to degrade safely while demonstrating optimal imaging characteristics as a result of
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Harms, Steven, Gail Lebovic, Cary Steven Kaufman, and Michael Cross. "Mammographic imaging after partial breast reconstruction: Impact of a bioabsorbable breast implant." Journal of Clinical Oncology 33, no. 28_suppl (2015): 111. http://dx.doi.org/10.1200/jco.2015.33.28_suppl.111.

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111 Background: Marking the site of the excised tumor bed during partial mastectomy is critical for radiation targeting and surveillance for breast cancer recurrence. However, delineating the lumpectomy cavity margins is challenging, and dense fibrosis and scarring often present obstacles when reviewing post-operative mammograms for signs of early recurrence. To determine whether implantation of a "mini" breast implant used for partial breast reconstruction adversely affected post-operative breast imaging, we reviewed clinical imaging of 100 patients that had been implanted with a new bioabsor
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Tallarico, Marco, Nicola Baldini, Matteo Martinolli, et al. "Do the New Hydrophilic Surface Have Any Influence on Early Success Rate and Implant Stability during Osseointegration Period? Four-Month Preliminary Results from a Split-Mouth, Randomized Controlled Trial." European Journal of Dentistry 13, no. 01 (2019): 095–101. http://dx.doi.org/10.1055/s-0039-1688737.

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Abstract Objective The objective of this study is to compare the implant stability of Hiossen ET III implants with its new hydrophilic (NH) surface and Hiossen ET III implants with the sandblasted and acid-etched (SA) surface. Materials and Methods Patients required at least two teeth to be rehabilitated with a fixed, implant-supported restoration, consecutively enrolled. Patients randomly received SA surface implants (SA group) or SA implants with a newly developed bioabsorbable apatite nanocoating (NH group). Outcome measures were implant and prosthetic survival rate, complications, insertio
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Huolman, Riikka, and Nureddin Ashammakhi. "New Multifunctional Anti-Osteolytic Releasing Bioabsorbable Implant." Journal of Craniofacial Surgery 18, no. 2 (2007): 295–301. http://dx.doi.org/10.1097/scs.0b013e31802e2a85.

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Guthrie, James, and Noel Fitzpatrick. "Single-Stage Revision of an Infected Total Hip Replacement Using Antibiotic-Impregnated Bioabsorbable Beads in a Canine Patient." VCOT Open 02, no. 01 (2019): e5-e12. http://dx.doi.org/10.1055/s-0038-1677523.

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AbstractThis report describes a technique and the outcome following surgical revision of a periprosthetic infected total hip replacement (THR) in a single-stage procedure with the use of antibiotic-impregnated bioabsorbable beads. A 6-year-old German Shepherd dog underwent THR 16 months previously, which subsequently became infected. The contaminated femoral and acetabular prostheses were explanted. A femoral window was used to remove the stem and cement. The endosteal surfaces of the femur and acetabulum were reamed to remove periprosthetic tissues. The femoral window was replaced and secured
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20

WARIS, E., N. ASHAMMAKHI, O. KAARELA, T. RAATIKAINEN, and J. VASENIUS. "Use of Bioabsorbable Osteofixation Devices in the Hand." Journal of Hand Surgery 29, no. 6 (2004): 590–98. http://dx.doi.org/10.1016/j.jhsb.2004.02.005.

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Bioabsorbable internal fixation by means of pins, tacks, screws and miniplates offers an alternative to metallic osteofixation for the stabilization of small bone fractures, osteotomies, ligament injuries and fusions in the hand. The advantages of using them include avoidance of metallic-implant-related long-term complications and a secondary removal operation. Currently the most commonly used devices are made of poly l-lactide (PLLA) and copolymers of polylactides (P(L/DL)LA) and polyglycolide (PLGA). In areas of mechanical stress, the use of ultra-high-strength self-reinforced devices is rec
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Ford, Timothy C., Kevin Brown, Trinity Mereau, and David Seligson. "NuGen Fx Bioabsorbable Screws." Journal of the American Podiatric Medical Association 96, no. 1 (2006): 73–77. http://dx.doi.org/10.7547/0960073.

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A single prospective group study in adults was performed using a new bioabsorbable screw, the NuGen Fx screw (Linvatec Biomaterials Ltd, Tampere, Finland). This multisite study included five sites and 50 patients (10 patients per site). The goal of this study was to evaluate the efficiency and safety of the NuGen Fx screw system in the fixation of osteotomies, arthrodeses, and fractures in the foot and ankle. We discuss our own results from 12 patients treated at the Kentucky Podiatric Residency Program at Norton Audubon Hospital, Louisville. The number of patients in the study, screw sizes, i
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Gabay Bass, Noa, Galit Katarivas Levy, Tomer Ron, et al. "Electrochemical Behaviour and Direct Cell Viability Analysis of Hybrid Implants Made of Ti-6Al-4V Lattices Infiltrated with a Bioabsorbable Zn-Based Alloy." Metals 12, no. 10 (2022): 1735. http://dx.doi.org/10.3390/met12101735.

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Biodegradable metals are being developed for biomedical implants or components of implants. Biodegradable zinc-based materials, in particular, have been shown to promote bone regeneration in orthopaedic applications. Here, we investigated the potential of a hybrid Ti-Zn system, comprising a Ti-6Al-4V biostable lattice produced by additive manufacturing (AM) infiltrated by a bioabsorbable Zn-2%Fe alloy, to serve as an osseointegrated implant for dental and orthopaedic applications. The osseointegration of implants can be enhanced by a porous implant structure that facilitates bone ingrowth to a
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Craig, Ronald G., Angela R. Kamer, Sathya P. Kallur, Miho Inoue, and Dennis P. Tarnow. "Effects of Periodontal Cell Grafts and Enamel Matrix Proteins on the Implant–Connective Tissue Interface: A Pilot Study in the Minipig." Journal of Oral Implantology 32, no. 5 (2006): 228–36. http://dx.doi.org/10.1563/820.1.

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Abstract We have developed an experimental model to help identify and characterize factors necessary for periodontal connective tissue attachment formation on dental implants. In this pilot study, we report the effect of autogenous periodontal cell grafts, with and without the application of enamel matrix derivative (EMD), on the implant–connective tissue interface. Periodontal ligament (PDL) and gingival connective tissue (GCT) cultures were established from an adult minipig. Implants were placed in osteotomies prepared with exaggerated countersinks that served as recipient sites for autogeno
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Lyutkevych, M. "Differentiated approach in the treatment of fractures of the distal humerus in children based on the use of bioabsorbable implants." Paediatric Surgery. Ukraine, no. 1(74) (March 30, 2022): 97–98. http://dx.doi.org/10.15574/ps.2022.74.97.

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In the practice of pediatric traumatologists there are a number of complex problems in the treatment of fractures of the distal humerus, which require a differentiated approach: atraumatic anatomical reposition with minimal damage to active growth zones, minimal damage to articular cartilage during surgery, stable fixation and early rehabilitation. At present, the generally accepted methods of osteosynthesis (fixation with K - wires, metal screws, etc.) do not fully meet the requirements of modern pediatric traumatology. One of the newest methods of fixation in the treatment of fractures of th
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Guan, Zeyi, Chase S. Linsley, Injoo Hwang, Gongcheng Yao, Benjamin M. Wu, and Xiaochun Li. "Novel zinc/tungsten carbide nanocomposite as bioabsorbable implant." Materials Letters 263 (March 2020): 127282. http://dx.doi.org/10.1016/j.matlet.2019.127282.

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Umer, Hafiz Muhammad, Hafiz Javaid Iqbal, and Raghuram Thonse. "Unusual osteochondral fracture of the second metatarsal head in a paediatric patient treated with bioabsorbable pin." BMJ Case Reports 14, no. 2 (2021): e238376. http://dx.doi.org/10.1136/bcr-2020-238376.

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Osteochondral second metatarsal head fractures are rare. Various management options have been described in the published literature. We used bioabsorbable pin (Activa Pin) system for our case of second metatarsal head fracture. This method not only achieves good compressive fixation, it also eliminates the risk of implant-related issues such as implant irritation. To our knowledge, no such paediatric case managed with this technique has been published in the literature.
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Patel, Vishal S., Evan Walgama, Alkis Psaltis, Francois Lavigne, Steven D. Pletcher, and Peter H. Hwang. "Biocompatibility and Pharmacokinetics of Fluticasone-Eluting Sinus Implant in a Rabbit Model." American Journal of Rhinology & Allergy 31, no. 6 (2017): 382–88. http://dx.doi.org/10.2500/ajra.2017.31.4481.

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Background A novel, bioabsorbable, fibrinogen-based implant has been developed as a mucosal dressing after endoscopic sinus surgery (ESS). This implant can be formulated with fluticasone propionate (TP) for local elution of corticosteroid to reduce postoperative inflammation and promote mucosal healing. Objective This study investigated the biocompatibility and pharmacokinetics of the implant in a rabbit model. Methods Implants with and without TP were placed on both intact and demucosalized maxillary sinuses of 33 New Zealand White rabbits. Sinuses with either intact or denuded bone without i
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Hasan, Saqib, Samir Nayyar, Ikemefuna Onyekwelu, Kunal Kalra, Soterios Gyftopoulos, and Laith M. Jazrawi. "Complications Using Bioabsorbable Cross-Pin Femoral Fixation: A Case Report and Review of the Literature." Case Reports in Radiology 2011 (2011): 1–6. http://dx.doi.org/10.1155/2011/349230.

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The use of bioabsorbable cross-pin transcondylar fixation has remained a viable option for femoral fixation in anterior cruciate ligament reconstruction. Although numerous biomechanical studies have demonstrated high fixation strength and minimal slippage with use of this method of fixation, there have been increasing reports of a variety of clinical complications associated with these implants. We reviewed the literature for all complications associated with the Bio-TransFix implant and present a case report of a patient status after ACL reconstruction using Bio-TransFix cross-pin femoral fix
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Covani, Ugo, Simone Marconcini, Roberto Crespi, and Antonio Barone. "Immediate Implant Placement After Removal of a Failed Implant: A Clinical and Histological Case Report." Journal of Oral Implantology 35, no. 4 (2009): 189–95. http://dx.doi.org/10.1563/1548-1336-35.4.189.

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Abstract The purpose of this study was to evaluate the clinical success of an implant placed immediately after the explantation of a fractured blade implant. A healthy 58-year-old male nonsmoker presented with a fractured blade implant that had been subjected to biomechanical overload. A new blade implant was placed immediately after the removal of the fractured one. The new implant was placed with a composite graft of collagen gel and corticocancellous porcine bone and covered with a bioabsorbable membrane. Radiographic evaluation at 6 months postoperation showed complete bone healing. No res
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Turan, Adil, Yusuf Alper Kati, Baver Acar, and Ozkan Kose. "Magnesium Bioabsorbable Screw Fixation of Radial Styloid Fractures: Case Report." Journal of Wrist Surgery 09, no. 02 (2019): 150–55. http://dx.doi.org/10.1055/s-0039-1685489.

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Abstract Background Several types of fixation materials may be used for the radial styloid fractures such as Kirschner wire fixation, screw fixation, volar plate fixation, and fragment-specific radial buttress plate fixation. However, each of these fixation techniques has certain complications usually related to either the surgical dissection or the application of fixation and symptomatic permanent hardware. Implant removal secondary to irritation of prominent screw heads or bulky plates is not uncommon after radial styloid fracture fixation. Case Description Herein, two patients with an isola
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Tomasino, Andre, Harry Gebhard, Karishma Parikh, Christian Wess, and Roger Härtl. "Bioabsorbable instrumentation for single-level cervical degenerative disc disease: a radiological and clinical outcome study." Journal of Neurosurgery: Spine 11, no. 5 (2009): 529–37. http://dx.doi.org/10.3171/2009.6.spine08838.

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Object The authors present the radiological and clinical outcome data obtained in patients who underwent single-level anterior cervical discectomy and fusion (ACDF) for cervical spondylosis and/or disc herniation; bioabsorbable plates were used for instrumentation. The use of metallic plates in ACDF has gained acceptance as a stabilizing part of the procedure to increase fusion rates, but when complications occur with these devices, the overall effectiveness of the procedure is compromised. As a possible solution, bioabsorbable implants for ACDF have been developed. This study investigates the
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Ylinen, P., R. M. Tulamo, M. Kellomäki, P. Türmälä, P. Rokkanen, and T. Palmgren. "Lumbar intervertebral disc replacement using bioabsorbable self-reinforced poly-L-lactide full-threaded screws, or cylindrical implants of polylactide polymers, bioactive glass and Polyactive™." Veterinary and Comparative Orthopaedics and Traumatology 16, no. 03 (2003): 138–44. http://dx.doi.org/10.1055/s-0038-1632777.

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SummaryIntervertebral disc surgery leads to changes in the segmental anatomy and mobility, and subsequently to degenerative changes in the lumbar spine. Artificial intervertebral disc implants sufficient to replace the human lumbar intervertebral disc have been developed and the requirements for these defined. This is to our knowledge the first study on bioabsorbable intervertebral disc replacement implants. SR-PLLA screws, previously used in orthopaedic internal fixations, and cylindrical implants, specifially developed for this experimental preliminary study, were used to replace lumbar inte
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Coe, Jeffrey D. "Instrumented transforaminal lumbar interbody fusion with bioabsorbable polymer implants and iliac crest autograft." Neurosurgical Focus 16, no. 3 (2004): 1–9. http://dx.doi.org/10.3171/foc.2004.16.3.12.

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Object The purpose of this study was to evaluate the clinical and radiographic results in 31 patients from one center who underwent instrumented transforaminal lumbar interbody fusion (TLIF) for primarily degenerative indications. Methods Bioabsorbable polymer spacers manufactured with a copolymer of 70:30 poly(L-lactide-co-D,L-lactide) and filled with iliac crest autograft bone were used for the TLIF procedure. In this paper the details of this procedure, intermediate (1- to 2-year) clinical and radiographic outcomes, and the basic science and rationale for the use of bioabsorbable polymers a
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Tai, Chien-Cheng, Yu-Min Huang, Chen-Kun Liaw, et al. "Biocompatibility and Biological Performance of Additive-Manufactured Bioabsorbable Iron-Based Porous Interference Screws in a Rabbit Model: A 1-Year Observational Study." International Journal of Molecular Sciences 23, no. 23 (2022): 14626. http://dx.doi.org/10.3390/ijms232314626.

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This study evaluated the mid-term (12-month) biomechanical, biocompatibility, and biological performance of additive-manufactured bioabsorbable iron-based interference screws (ISs). Two bioabsorbable iron IS types—manufactured using pure iron powder (iron_IS) and using pure iron powder with 0.2 wt% tricalcium phosphate (TCP_IS)—were compared with conventional metallic IS (control) using in vitro biocompatibility and degradation analyses and an in vivo animal study. The in vitro ultimate failure strength was significantly higher for iron_IS and TCP_IS than for control ISs at 3 months post-opera
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Overbeck, J. P., S. T. Winckler, R. Meffert, P. Törmälä, H. U. Spiegel, and E. Brug. "Penetration of Ciprofloxacin into Bone: A New Bioabsorbable Implant." Journal of Investigative Surgery 8, no. 3 (1995): 155–62. http://dx.doi.org/10.3109/08941939509023138.

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Weber, Stephen C., and Jeffrey I. Kauffman. "Distant migration of a bioabsorbable implant in the shoulder." Journal of Shoulder and Elbow Surgery 15, no. 6 (2006): e48-e53. http://dx.doi.org/10.1016/j.jse.2005.11.005.

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Filip, Nina, Iulian Radu, Bogdan Veliceasa, et al. "Biomaterials in Orthopedic Devices: Current Issues and Future Perspectives." Coatings 12, no. 10 (2022): 1544. http://dx.doi.org/10.3390/coatings12101544.

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In orthopedics, bone fixation imposes the use of implants in almost all cases. Over time, the materials used for the implant have evolved from inert materials to those that mimic the morphology of the bone. Therefore, bioabsorbable, biocompatible, and bioactive materials have emerged. Our study aimed to review the main types of implant materials used in orthopedics and present their advantages and drawbacks. We have searched for the pros and cons of the various types of material in the literature from over the last twenty years. The studied data show that consecrated metal alloys, still widely
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Chagnon, Madeleine, Louis-Georges Guy, and Nicolette Jackson. "Evaluation of Magnesium-based Medical Devices in Preclinical Studies: Challenges and Points to Consider." Toxicologic Pathology 47, no. 3 (2019): 390–400. http://dx.doi.org/10.1177/0192623318816936.

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Absorbable metallic implants have been under investigation for more than a century. Animal and human studies have shown that magnesium (Mg) alloys can be safely used in bioresorbable scaffolds. Several cardiovascular and orthopedic biodegradable metallic devices have recently been approved for use in humans. Bioresorbable Mg implants present many advantages when compared to bioabsorbable polymer or nonabsorbable metallic implants, including similar strength and mechanical properties as existing implant-grade metals without the drawbacks of permanence or need for implant removal. Imaging visibi
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Aynardi, Michael, Kempland Walley, Jesse Hallam, Gearin Green, and Paul Juliano. "Mid-term Outcomes & Complications Following the Use of an Arthroereisis Implant to Aid in Stage II Flat-Foot Correction in Adults." Foot & Ankle Orthopaedics 2, no. 3 (2017): 2473011417S0000. http://dx.doi.org/10.1177/2473011417s000021.

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Category: Hindfoot Introduction/Purpose: The use of an arthroereisis implant to augment a stage II, flat-foot reconstruction in adults has been described and may improve postoperative alignment. Yet, painful hardware has been reported. Additionally, there are no reports of mid-term follow up on these implants. The purpose of this study is to describe the mid-term clinical and radiographic outcomes as well as complications with the use of an arthroereisis implant as an adjunct procedure for patients undergoing surgical correction of a flexible acquired, stage II, flat-foot deformity as compared
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Schlechter, John A., Shawn V. Nguyen, and Katie L. Fletcher. "Utility of Bioabsorbable Fixation of Osteochondral Lesions in the Adolescent Knee: Outcomes Analysis With Minimum 2-Year Follow-up." Orthopaedic Journal of Sports Medicine 7, no. 10 (2019): 232596711987689. http://dx.doi.org/10.1177/2325967119876896.

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Background: Osteochondral lesions (OCLs) of the knee, whether occurring secondary to osteochondritis dissecans or a traumatic osteochondral fracture, are commonly encountered in the pediatric and adolescent population. Given the potential for healing in this population, coupled with adequate surgical reduction and stability of OCL fixation, an opportunity exists to avoid a major restorative procedure and the associated substantial costs and potential morbidity. Purpose: To analyze the outcomes of bioabsorbable fixation of OCLs in the adolescent knee at a minimum of 2 years. Study Design: Case
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Benca, E., K. van Knegsel, I. Zderic, et al. "BIOMECHANICAL EVALUATION OF AN ALLOGRAFT FIXATION SYSTEM FOR ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION IN COMPARISON WITH THE INTERFERENCE SCREW." Orthopaedic Proceedings 105-B, SUPP_7 (2023): 42. http://dx.doi.org/10.1302/1358-992x.2023.7.042.

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Screw fixation is an established method for anterior cruciate ligament (ACL) reconstruction, although with a high rate of implant-related complications. An allograft system for implant fixation in ACL reconstruction, the Shark Screw ACL (surgebright GmbH) could overcome some of the shortcomings of bioabsorbable screws, such as foreign body reaction, need for implant removal and imaging artefacts. However, it needs to provide sufficient mechanical stability. Therefore, the aim of this study was to investigate the biomechanical stability, especially graft slippage, of the novel allograft system
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42

Lowry, K. J., K. R. Hamson, L. Bear, et al. "Polycaprolactone/glass bioabsorbable implant in a rabbit humerus fracture model." Journal of Biomedical Materials Research 36, no. 4 (1997): 536–41. http://dx.doi.org/10.1002/(sici)1097-4636(19970915)36:4<536::aid-jbm12>3.0.co;2-8.

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Donley, Brian G., Clinton Jambor, Ahmet Erdermier, James Sferra, and Peter Cavanagh. "Effect of Pilot-Hole Size on the Pullout Strength of Flexor Digitorum Longus Transfer Fixed with a Bioabsorbable Screw." Foot & Ankle International 28, no. 10 (2007): 1078–81. http://dx.doi.org/10.3113/fai.2007.1078.

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Background: Fixation of tendon transfers with a bioabsorbable interference-fit screw has several advantages over other fixation methods: decreased dissection, operative time, and blood loss; preservation of tendon length; no interference with radiographic studies; no need for implant removal; and no barrier to revision surgery. Whether strength of fixation is affected by the size of the pilot hole has not been established. The purpose of this study was to determine the effect of pilot hole size on the pullout strength of a flexor digitorum longus (FDL) tendon secured into a bone analog using a
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44

Suuronen, Riitta, Risto Kontio, Nureddin Ashammakhi, Christian Lindqvist, and Pekka Laine. "Bioabsorbable self‐reinforced plates and screws in craniomaxillofacial surgery." Bio-Medical Materials and Engineering 14, no. 4 (2004): 517–24. https://doi.org/10.1177/095929892004014004016.

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Bioabsorbable fixation devices have been used in craniomaxillofacial (CMF) surgery since the early 70's. In our departments the experimental use started in the 80's with self‐reinforced (SR) polylactide devices. The first clinical operations were carried out in 1991. Since that time, we have used different types of self‐reinforced bioabsorbable devices in the fixation of several hundreds of osteotomies and fractures. Patients' acceptance has been generally excellent and very few complications occurred during this follow‐up of over 10 years. The complications have been minor and have not affect
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Lippman, Caleb R., Michael Hajjar, Bret Abshire, George Martin, Robert W. Engelman, and David W. Cahill. "Cervical spine fusion with bioabsorbable cages." Neurosurgical Focus 16, no. 3 (2004): 1–10. http://dx.doi.org/10.3171/foc.2004.16.3.5.

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Object Although it improves rates of fusion in surgical arthrodesis, conventional spinal instrumentation is associated with several risks, including hardware extrusion that injures adjacent anatomical structures, and disuse osteopenia as a result of stress shielding. The long-term effects of indwelling spinal instrumentation, although incompletely documented, may be detrimental. One way to avoid such problems would be to use bioabsorbable implantation devices. In this pilot study, performed in 1998 and 1999, the authors evaluated the use of a bioabsorbable interbody fusion device in a goat cer
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46

Govender, Stan, John Harman, Gail Lebovic, John Simpson, and Benji Benjamin. "A new method for partial breast reconstruction: 3-year New Zealand experience." Journal of Clinical Oncology 33, no. 28_suppl (2015): 89. http://dx.doi.org/10.1200/jco.2015.33.28_suppl.89.

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89 Background: Most women in New Zealand undergo partial mastectomy (PM) and 6 weeks of whole breast irradiation for early breast cancer. Oncoplastic surgery (OPS) is common, however, reconstruction of the breast during partial mastectomy presents challenges for radiation targeting since tissues have been extensively rearranged. Further complicating matters, the seroma cavity is often absent, and many patients travel to different cities for radiation without much communication between the surgeon and radiation oncologist prior to treatment. Throughout the country there is interest in promoting
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De Oliveira, Felipe Alves. "Bioabsorbable pins at the knee - normal imaging findings and complications." Brazilian Journal of Health Review 7, no. 1 (2024): 5793–804. http://dx.doi.org/10.34119/bjhrv7n1-469.

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The traumatic and non-traumatic osteochondral lesions of the knee can be surgically repaired with osteochondral fragment fixation, and bioabsorbable materials have been facing a strong increase in their use for this purpose in recent years. They have specific biomechanical and biological behavior after implantation, which depict normal and abnormal imaging findings on follow-up diagnostic imaging. This article will discuss these and other imaging findings, important to predict implant failure leading to poor evolution and associated complications.
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Hung, Chun Ho, Yui Chit Kwok, Jason Yip, Ho Hin Wong, and Yiu Yan Leung. "Bioabsorbable Magnesium-Based Materials Potential and Safety in Bone Surgery: A Systematic Review." Craniomaxillofacial Trauma & Reconstruction 18, no. 2 (2025): 24. https://doi.org/10.3390/cmtr18020024.

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The goal of this study was to evaluate the clinical outcomes, safety, and clinical applications of bioabsorbable magnesium-based materials for fixation in bone surgeries. The review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. An initial search was performed on electronic databases, followed by manual and reference searches. The articles selected were evaluated for patient characteristics, biocompatibility, the need for revision surgery, bone union rates, and the incidence of gas formation associated with implant degradation.
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Mattila, S., and E. Waris. "Unfavourable short-term outcomes of a poly-L/D-lactide scaffold for thumb trapeziometacarpal arthroplasty." Journal of Hand Surgery (European Volume) 41, no. 3 (2015): 328–34. http://dx.doi.org/10.1177/1753193415601952.

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The bioabsorbable poly-L-D-lactide joint scaffold arthroplasty is a recent attempt in the reconstruction of small joints in rheumatoid patients. In this study, we analysed the 1-year clinical, functional and radiologic results of partial trapeziectomy with the poly-L-D-lactide (96/4) joint scaffold in 23 patients with isolated trapeziometacarpal osteoarthritis. The results showed that the procedure provided pain relief and improvement in overall function according to the Quick Disabilities of the Arm, Shoulder and Hand score in most patients. However, radiographs demonstrated a high frequency
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Tai, Chien-Cheng, Hon-Lok Lo, Chen-Kun Liaw, et al. "Biocompatibility and Biological Performance Evaluation of Additive-Manufactured Bioabsorbable Iron-Based Porous Suture Anchor in a Rabbit Model." International Journal of Molecular Sciences 22, no. 14 (2021): 7368. http://dx.doi.org/10.3390/ijms22147368.

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This study evaluated the biocompatibility and biological performance of novel additive-manufactured bioabsorbable iron-based porous suture anchors (iron_SAs). Two types of bioabsorbable iron_SAs, with double- and triple-helical structures (iron_SA_2_helix and iron_SA_3_helix, respectively), were compared with the synthetic polymer-based bioabsorbable suture anchor (polymer_SAs). An in vitro mechanical test, MTT assay, and scanning electron microscope (SEM) analysis were performed. An in vivo animal study was also performed. The three types of suture anchors were randomly implanted in the outer
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