Relevant bibliographies by topics / Bioactive

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Academic literature on the topic 'Bioactive'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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Journal articles on the topic "Bioactive"

Ouma, Stephen, Richard Kagia, and Faith Kamakia. "Determination of pharmacological activity of bioactives in Allium sativum using computational analysis." F1000Research 12 (February 9, 2023): 151. http://dx.doi.org/10.12688/f1000research.130105.1.

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Introduction: Use of natural products for management of diseases has increased widely due to the belief that natural products are less toxic than conventional medicines. Natural products have been utilised for management of chronic diseases such as diabetes and cancers. Respiratory infections have also been managed using natural products. Allium sativum is one of the natural products that has been utilised in the management of SARS-CoV infections, diabetes and cancer. Methods: This study was aimed at screening bioactive agents in Allium sativum using computational analysis. The targets of the

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Postružnik, Vesna, Slađana Stajčić, Dragana Borjan, et al. "Impact of Storage Conditions on Stability of Bioactive Compounds and Bioactivity of Beetroot Extract and Encapsulates." Processes 12, no. 7 (2024): 1345. http://dx.doi.org/10.3390/pr12071345.

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(1) Background: In this study, bioactive compounds (phenolics and betalains) extracted from beetroot were stabilized by encapsulation with maltodextrin and soy protein by the freeze drying method. Stability of bioactive compounds and bioactivities in a beetroot extract and encapsulates during 60 days of storage at 4 °C (without light) and at 25 °C (with and without light) were investigated. (2) Methods: Contents of bioactive compounds and bioactivity (antioxidant activity by DPPH, RP, and ABTS tests; anti-inflammatory and antihyperglycemic activity) were determined. Improvement in stability of

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Yates, Allison A., Johanna T. Dwyer, John W. Erdman, et al. "Perspective: Framework for Developing Recommended Intakes of Bioactive Dietary Substances." Advances in Nutrition 12, no. 4 (2021): 1087–99. http://dx.doi.org/10.1093/advances/nmab044.

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ABSTRACT Dietary bioactives are food substances that promote health but are not essential to prevent typical deficiency conditions. Examples include lutein and zeaxanthin, omega-3 fatty acids, and flavonoids. When quality evidence is available, quantified intake recommendations linking dietary bioactives with specific health benefits will enable health professionals to provide evidence-based information to consumers. Without evidence-based recommendations, consumers use information from available sources that often lack standards and rigor. This article describes a framework to develop guidanc

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Evans, Levi W., Samantha S. Romanick, and Bradley S. Ferguson. "Natural product inhibitors of acetyl-lysine erasers in the prevention and treatment of heart failure." Functional Foods in Health and Disease 7, no. 8 (2017): 577. http://dx.doi.org/10.31989/ffhd.v7i8.376.

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Background: Heart failure (HF) is a major public health concern, with five-year mortality rates following first admission for HF being approximately 50%, thereby stressing the need for novel therapeutic approaches. Histone deacetylases (HDACs) govern lysine acetylation of histone tails that regulates nucleosmal DNA. HDAC inhibitors have emerged as efficacious therapies in pre-clinical models of HF. Interest in diet-gene interactions has given rise to the study of ‘food bioactives’ as epigenetic regulators of gene expression that control human health and disease. These reports demonstrate that

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Ramadan, Mohamed Fawzy, Alessandra Durazzo, and Massimo Lucarini. "Advances in Research on Food Bioactive Molecules and Health." Molecules 26, no. 24 (2021): 7678. http://dx.doi.org/10.3390/molecules26247678.

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Fresh and processed food products are rich in bioactive molecules, including polysaccharides, vitamins, carotenoids, peptides, antioxidants, phenolics, phytosterols, and novel lipids. Bioactive molecules in food could prevent several diseases (i.e., metabolic syndrome, cardiovascular diseases, cancer, etc.). Thus, consumer awareness is growing about the health-promoting impact of food bioactive molecules. Health claims are essential added-value features, wherein health-enhancing potential of bioactives depend on their chemical structure. On the other hand, the investigation of the structure-fu

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Bordoni, A., C. Boesch, C. Malpuech-Brugère, C. Orfila, and L. Tomás-Cobos. "The role of bioactives in energy metabolism and metabolic syndrome." Proceedings of the Nutrition Society 78, no. 3 (2019): 340–50. http://dx.doi.org/10.1017/s0029665119000545.

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Some food bioactives potentially exert anti-obesity effects. Anthocyanins (ACN), catechins, β-glucan (BG) and n-3 long chain PUFA (LCPUFA) are among the most promising candidates and have been considered as a strategy for the development of functional foods counteracting body weight gain. At present, clinical trials, reviews and meta-analyses addressing anti-obesity effects of various bioactives or bioactive-rich foods show contradictory results. Abdominal obesity is an important criterion for metabolic syndrome (MetS) diagnosis along with glucose intolerance, dyslipidaemia and hypertension. F

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Cecchi, Nicola, Roberta Romanelli, Flavia Ricevuti, et al. "Bioactives in Oral Nutritional Supplementation: A Pediatric Point of View." Nutrients 16, no. 13 (2024): 2067. http://dx.doi.org/10.3390/nu16132067.

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Background: Oral nutritional supplements (ONSs) are crucial for supporting the nutritional needs of pediatric populations, particularly those with medical conditions or dietary deficiencies. Bioactive compounds within ONSs play a pivotal role in enhancing health outcomes by exerting various physiological effects beyond basic nutrition. However, the comprehensive understanding of these bioactives in pediatric ONSs remains elusive. Objective: This systematic narrative review aims to critically evaluate the existing literature concerning bioactive compounds present in oral nutritional supplements

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Günal-Köroğlu, Deniz, Aysenur Betul Bilgin, Gulsah Karabulut, Beyza Saricaoglu, and Esra Capanoglu. "Encapsulation of hydrophobic compounds in yeast cells: methods, characterization, and applications." Exploration of Foods and Foodomics 2, no. 3 (2024): 252–74. http://dx.doi.org/10.37349/eff.2024.00037.

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Encapsulation is a pivotal technique for protecting and enhancing the efficiency of sensitive natural bioactive substances, notably essential oils, vitamins, and phenolic compounds, widely used in foods and nutraceuticals. Critical considerations in selecting encapsulation agents encompass safety, release kinetics, stability, and cost-effectiveness. Yeast cells emerge as versatile carriers distinguished by their low cost, compatibility with biological systems, and eco-friendly degradation properties, accommodating both hydrophilic and hydrophobic bioactive agents. Various yeast strains, includ

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K B S, Sushma. "Bioactive Glass: A Review." International Journal of Science and Research (IJSR) 12, no. 6 (2023): 1645–49. http://dx.doi.org/10.21275/sr23612165802.

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Donsì, Francesco, and Giovanna Ferrari. "Changing the Vision in Smart Food Design Utilizing the Next Generation of Nanometric Delivery Systems for Bioactive Compounds." Foods 9, no. 8 (2020): 1100. http://dx.doi.org/10.3390/foods9081100.

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In modern foods, the delivery systems for bioactive compounds play a fundamental role in health promotion, wellbeing, and disease prevention through diet. Nanotechnology has secured a fundamental role in the fabrication of delivery systems with the capability of modulating the in-product and in-body behavior for augmenting bioavailability and activity of bioactive compounds. Structured nanoemulsions and nanoparticles, liposomes, and niosomes can be designed to improve bioactives preservation after ingestion, mucoadhesion, as well as of their release and pathophysiological relevance. In the fut

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Dissertations / Theses on the topic "Bioactive"

Wilcox, Matthew David. "Bioactive alginates." Thesis, University of Newcastle Upon Tyne, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.578262.

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Alginates are polysaccharides extracted from the cell walls of brown seaweed or from certain bacteria such as Azotobacter vinelandii. Alginates have been shown to reduce the activity of pepsin and initial data suggest that it may affect the activity of pancreatic lipase. Pancreatic lipase plays an important role in the breakdown of triacylglycerol, if the activity of pancreatic lipase can be reduced then the breakdown of triacylglycerol would be reduce which in turn would lower the amount absorbed by the body. A pharmaceutical treatment for obesity called orlistat inhibits lipase and accounts

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Woods, Katherine B. "Bioactive natural products." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/26234.

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Montbretins A-E were isolated from the corms of Crocosmia sp., an invasive perennial plant. The montbretins are inhibitors of human pancreatic α-amylase (HPA). Montbretin A (2- 30) is a competitive inhibitor of HPA with a K₁ of 1.3 nM. The activity of the other family members varied significantly and provided structure-activity information. Saturation Transfer Difference (STD) NMR spectroscopy was used to determine that the caffeic acid region of the montbretins is important for binding. HPA is involved in the breakdown of complex carbohydrates; inhibition of this enzyme could help with regula

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Drummond, Allison K. "Bioactive metabolites from microorganisms /." Electronic version (PDF), 2006. http://dl.uncw.edu/etd/2006/drummonda/allisondrummond.pdf.

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Lavelle, S. P. "Characterisation of bioactive aerosols." Thesis, London South Bank University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618633.

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Desjardine, Kelsey Lorne. "Bioactive marine natural products." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31286.

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The chemical exploration of extracts from cultures of the marine bacterial isolate PNG-276 yielded the novel antibiotic tauramamide (2.13), a non-ribosomal peptide active against cultures of Enterococcus sp. and methicillin-resistant Staphylococcus aureus (MRSA). A study of extracts of the marine sponge Spirastrella coccinea yielded the novel macrolide methylspirastrellolide C (3.14), which is active against protein phosphatase 2A (PP2A). A third study examined sponge extracts active in a cannabinoid receptor assay, yielding two known compounds, an A- nor -steroid derivative (4.10) and bengami

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Zhang, Yulan. "Diffusion of bioactive molecules." Thesis, University of Birmingham, 2013. http://etheses.bham.ac.uk//id/eprint/3982/.

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An artificial liposome membrane system has been employed for in vitro screening of the human absorption of biologically active molecules for applications in nutrition and drug treatments. Initial work with molecules having small permeabilities demonstrated that they could not be measured using the technique since they were absorbed by the membrane. A critical innovation was to pre-treat the membrane by equilibrating it with the molecule of interest since this avoids the absorption problem but required more complex data analysis. Bioactive molecules with strong antioxidant and anti-cancer activ

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Xinping, X. "Bioactive peptides from phyllomedusinae." Thesis, Queen's University Belfast, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.677853.

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For thousands of years, Nature has' been considered to be essential for human beings for the treatment of their diseases. Amphibians are an important component of the Animal Kingdom and have played a significant role in sourcing many active compounds and some therapeutics. In the course of this research, genomic and proteomic techniques have been used to investigate the bioactive peptides from the skin secretions of four American amphibian species: the Central American red-eyed leaf frog, Agalychnis callidryas~ the South American orange-legged leaf frog, Phyllomedusa hypochondrialis, Rohde's l

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She, Fengyu. "Development of Bioactive Peptidomimetics." Scholar Commons, 2018. https://scholarcommons.usf.edu/etd/7571.

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Peptidomimetics are synthetic foldamers that expected more resistant to proteolytic degradation and enormous chemodiversity when compared with peptides. To date, the functional peptidomimetics such as β-peptides, peptoids, oligoureas, etc have been developed in many science fields. In order to explore the unnatural foldameric architectures, it’s necessary to discover the novel frameworks and molecular scaffolds. γ-AApeptides were reported to be a new class of peptidomimetics that showed its potential applications in drug discovery and chemical biology. However, a wide function and property of

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Martínez, Subirà Mariona. "Hull-less and coloured-grain barley as a source of valuable healthy bioactive compounds." Doctoral thesis, Universitat de Lleida, 2021. http://hdl.handle.net/10803/672377.

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Tot i que poques vegades es fa servir en els aliments, l'ordi està rebent un interès creixent com un gra saludable, per les seves propietats nutricionals. Es van estudiar a camp genotips d'ordi sense cobertes i de gra acolorit que es diferenciaven en una varietat de compostos bioactius valuosos i saludables, en diferents condicions ambientals i de temperatura. L'estrès per alta temperatura durant l'ompliment del gra va augmentar la concentració de compostos bioactius claus en el gra. S'ha de considerar la collita primerenca de grans immadurs per maximitzar la capacitat antioxidant. El 30% més

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Sandoval, Sandoval Viviana Paz. "Impact on gene expression and metabolic homeostasis of bioactive compounds-enriched diets." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/671150.

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The excess of fat deposits are originated by a prolonged imbalance between the energy intake and the energy expenditure. The current food pattern based on a high consumption of saturated fats, simple sugars and processed foods, together with the sedentary lifestyle of the population, favor the development of obesity, which is responsible for 3.4 million deaths per year and is the main risk factor for the development of associated comorbidities, such as type 2 diabetes mellitus, non-alcoholic fatty liver and cardiovascular diseases. Given the current pandemic scope of obesity,

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Books on the topic "Bioactive"

Boccaccini, Aldo R., Delia S. Brauer, and Leena Hupa, eds. Bioactive Glasses. Royal Society of Chemistry, 2016. http://dx.doi.org/10.1039/9781782622017.

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Onuh, John Oloche, M. Selvamuthukumaran, and Yashwant V. Pathak, eds. Bioactive Peptides. CRC Press, 2021. http://dx.doi.org/10.1201/9781003052777.

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Börner, Hans G., and Jean-Francois Lutz, eds. Bioactive Surfaces. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-20155-4.

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Kaur, Gurbinder. Bioactive Glasses. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-45716-1.

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Thakur, Monika, and Tarun Belwal, eds. Bioactive Components. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-2366-1.

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T, Peters, and Evans S. V. 1959-, eds. Bioactive conformation. Springer, 2007.

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John, Howl, and Jones Sarah Dr, eds. Bioactive peptides. CRC Press/Taylor & Francis, 2009.

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Nicolaou, Anna, and George Kokotos. Bioactive lipids. The Oily Press, 2004.

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Eguchi, Shoji. Bioactive heterocycles. Edited by Eguchi Shoji. Springer, 2006.

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Jean-François, Lutz, and SpringerLink (Online service), eds. Bioactive Surfaces. Springer-Verlag Berlin Heidelberg, 2011.

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Book chapters on the topic "Bioactive"

Uemura, Daisuke. "Bioactive Polyethers." In Bioorganic Marine Chemistry. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76320-5_1.

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Chouzouri, Georgia, and Marino Xanthos. "Bioactive Fillers." In Functional Fillers for Plastics. Wiley-VCH Verlag GmbH & Co. KGaA, 2005. http://dx.doi.org/10.1002/3527605096.ch22.

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Rodan, Katie, Kathy Fields, and Timothy Falla. "Bioactive Peptides." In Cosmeceuticals and Cosmetic Practice. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118384824.ch14.

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Vázquez, Luis, Marta Corzo-Martínez, Pablo Arranz-Martínez, Elvira Barroso, Guillermo Reglero, and Carlos Torres. "Bioactive Lipids." In Bioactive Molecules in Food. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-78030-6_58.

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Chouzouri, Georgia, and Marino Xanthos. "Bioactive Fillers." In Functional Fillers for Plastics. Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527629848.ch22.

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de Oliveira, Camila Areias, and Michelli Ferrera Dario. "Bioactive Cosmetics." In Handbook of Ecomaterials. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-48281-1_157-1.

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Kiessling, Laura L., and Laura E. Strong. "Bioactive Polymers." In Topics in Organometallic Chemistry. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/3-540-69708-x_8.

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Hupa, Leena, Xiaoju Wang, and Siamak Eqtesadi. "Bioactive Glasses." In Springer Handbook of Glass. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-93728-1_23.

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West, Jennifer L., and Jeffrey A. Hubbell. "Bioactive Polymers." In Synthetic Biodegradable Polymer Scaffolds. Birkhäuser Boston, 1997. http://dx.doi.org/10.1007/978-1-4612-4154-6_5.

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LeGeros, Racquel Z., Guy Daculsi, and John P. LeGeros. "Bioactive Bioceramics." In Musculoskeletal Tissue Regeneration. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-239-7_8.

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Conference papers on the topic "Bioactive"

Polo, Ester. "Bioactive Colloidal Nanosystems." In Advanced materials and devices for nanomedicine. Fundació Scito, 2022. http://dx.doi.org/10.29363/nanoge.amamed.2022.032.

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Khan, Mohidus Samad, Junfei Tian, Li Xu, Wei Shen, and Gil Garnier. "Bioactive Enzymatic Papers." In Advances in Pulp and Paper Research, Oxford 2009. Fundamental Research Committee (FRC), Manchester, 2009. http://dx.doi.org/10.15376/frc.2009.2.1149.

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The thermal stability of Alkaline phosphatase enzyme (ALP) adsorbed on paper was measured using a colorimetric technique quantifying the intensity of the product complex. ALP adsorbed on paper retains its functionality and selectivity. Adsorption of ALP on paper increased the enzyme thermal stability by 2 to 4 orders of magnitude compared to the same enzyme in solution. Complex patterns of enzyme were also printed using a thermal inkjet printer on paper. Microﬂuidic channels were printed on paper to demonstrate the concept of paper-based bioassays as diagnostic devices. Paper is an ideal mater

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Graubmann, Julia E., Sigrid Seuβ, and Aldo R. Boccaccini. "Soft Bioactive Coatings based on Electrophoretically Deposited Bioactive Glass Nanoparticles and Polycaprolactone." In Biomedical Engineering. ACTAPRESS, 2013. http://dx.doi.org/10.2316/p.2013.791-101.

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Lepienski, Carlos, and Eduardo Mioduski Szesz. "Bioactive response on Ti alloy surface induced by anodically bonded bioactive glass." In 24th ABCM International Congress of Mechanical Engineering. ABCM, 2017. http://dx.doi.org/10.26678/abcm.cobem2017.cob17-0167.

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Dufossé, Laurent. "Microbial carotenoids as bioactive food ingredients." In Foods: Bioactives, Processing, Quality and Nutrition. MDPI, 2013. http://dx.doi.org/10.3390/bpqn2013-01169.

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Dufossé, Laurent. "Microbial aryl carotenoids as bioactive food ingredients." In Foods: Bioactives, Processing, Quality and Nutrition. MDPI, 2013. http://dx.doi.org/10.3390/bpqn2013-01295.

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Kessler, Horst, Robert Konat, Michael Kurz, and Chaim Gilon. "Conformational design of bioactive peptides." In Future Aspect in Peptide Chemistry - Ringberg Conference. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 1999. http://dx.doi.org/10.1135/css199901086.

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Kwak, M., JS Kim, and TK Hyun. "Variation in bioactive compounds and bioactive principles of rosehip (Rosa rugosa Thunb.) during repening." In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3400146.

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Pelton, Robert. "Review: Bioactive Paper – A Paper Science Perspective." In Advances in Pulp and Paper Research, Oxford 2009, edited by S. J. I’Anson. Fundamental Research Committee (FRC), Manchester, 2009. http://dx.doi.org/10.15376/frc.2009.2.1095.

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This paper reviews the initial developments in a new field we call “bioactive paper”. At the interface between the enormous global biomedical-biotechnology research activities and the small, esoteric world of paper science research, bioactive paper research targets exciting new paper products, improving quality of life world wide. The most exciting potential implementations of bioactive paper involve leading edge concepts in genetic engineering, biochemistry, and microbiology. Current bioactive paper initiatives are summarized herein from a paper technology perspective. Elementary descriptions

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Uzor, PF, and CO Nnadi. "Dereplication of Bioactive Markers from the Leaves of Anthocleista nobilis: Searching for new Bioactive Metabolites." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608074.

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Reports on the topic "Bioactive"

Taub, Floyd E. Fluorinated Analogs of Bioactive Garlic Components. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1018158.

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Taub, Floyd. Fluorinated Analogs of Bioactive Garlic Components. Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1035209.

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Honn, Kenneth. Bioactive Lipids: Role in Prostate Cancer Angiogenesis. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada405532.

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Honn, Kenneth V. Bioactive Lipids: Role in Prostate Cancer Angiogenesis. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada419706.

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Honn, Kenneth. Bioactive Lipids: Role in Prostate Cancer Angiogensis. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada384373.

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Teixeira, Carla, Caterina Villa, Joana Costa, Isabel M. P. L. V. O. Ferreira, and Isabel Mafra. Edible insects as a source of bioactive peptides. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.3.0075.

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Review question / Objective: This systematic review aimed at performing an exhaustive bibliographic search of all research articles reporting sequenced bioactive peptides obtained from edible insects and the respective properties demonstrated by in silico, in vitro and/or in vivo approaches. This report intends to evaluate the existing weigh-of-evidence regarding each specific claimed bioactive property, thus representing a valuable contribution to the divulgation of the scientific basis on the health benefits associated to the consumption of insects. Condition being studied: Insects are a goo

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López-Valverde, Nansi, Javier Aragoneses, Antonio López-Valverde, Cinthia Rodríguez, and Juan Manuel Aragoneses. Role in the osseointegration of titanium dental implants, of bioactive surfaces based on biomolecules: A systematic review and meta-analysis of in vivo studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.6.0076.

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Review question / Objective: Does the bioactive surface of titanium dental implants, based on biomolecules, influence osseointegration?. The aim of our study was to evaluate the role and efficacy of bioactive surfaces in osseointegration. Our review study limited the research interest to titanium dental implants coated with a biomolecule, i.e., an organic molecule produced by a living organism. Condition being studied: In recent years, much attention has been paid to topographical modifications of dental implant surfaces, as well as to their coating with biologically active substances.a bioact

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ตันติสิระ, มยุรี, บุญยงค์ ตันติสิระ та จุไรพร สมบุญวงศ์. การศึกษาฤทธิ์ในการสมานแผลและผลต่อการเรียนรู้และความจำของสารสกัดมาตรฐานบัวบกในโมเดลของสัตว์ทดลอง : รายงานการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2005. https://doi.org/10.58837/chula.res.2005.27.

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งานวิจัยนี้เป็นส่วนหนึ่งของชุดโครงการ “การวิจัยและพัฒนาผลิตภัณฑ์ยาและเครื่องสำอางที่มรมาตรฐานจากสมุนไพรบัวบกสู่การผลิตระดับอุตสาหกรรม” ซึ่งมีวัตถุประสงค์หลักที่มุ่งจะเตรียมสารสกัดมาตรฐานที่มีฤทธิ์แก้ไขสภาวะบกพร่องของการเรียนรู้และความจำ และสารสกัดมาตรฐานที่มีฤทธิ์สมานแผล โดยใช้วิธี activity-guided isolation แยกสารทดสอบไปทีละขั้นตอนเพื่อกำหนดสารที่เป็น bioactive markers ในสารสกัดมาตรฐาน โมเดลของสภาวะบกพร่องของการเรียนรู้และความจำที่ใช้คือการปิดกั้นหลอดเลือดคาโรติดชั่วคราว (2VO) และการฉีดสารสโคโปลามีน ส่วนโมเดลที่ใช้ในการทดสอบการสมานแผลก็คือแผนที่เกิดจากการกรีดและแผลที่เกิดจากความร้อน โดยทำการทด

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Honn, Kenneth. Phase I Bioactive Lipids: Role in Prostate Cancer Angiogenesis"". Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada394907.

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Yamil Liscano, Yamil Liscano. New bioactive peptides from skin of a colombian frog. Experiment, 2018. http://dx.doi.org/10.18258/10880.

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