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Relevant bibliographies by topics / Bioactive Heterocycles

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Academic literature on the topic 'Bioactive Heterocycles'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Bioactive Heterocycles"

1

Luna, Isadora Silva, Rayssa Marques Duarte da Cruz, Ryldene Marques Duarte da Cruz, Rodrigo Santos Aquino de Araújo, and Francisco Jaime Bezerra Mendonça-Junior. "1,4-Dithiane-2,5-diol: A Versatile Synthon for the Synthesis of Sulfur-containing Heterocycles." Current Organic Synthesis 15, no. 8 (2018): 1026–42. http://dx.doi.org/10.2174/1570179415666180821154551.

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Background: 1,4-Dithiane-2,5-diol (1,4-DTD) is the stable dimer of α-mercapto acetaldehyde. This commercially available ambidentade compound is characterized as having in its chemical structure one group that acts as an electrophile and another that acts as a nucleophile, this permits its use as versatile and efficient synthon in synthetic heterocycle procedures. Objective: The aim of this review is to present synthetic applications of 1,4-DTD in heterocyclic chemistry and their applicability to the synthesis of bioactive compounds. Conclusion: Gewald reactions to obtain C-4 and C-5 unsubstitu

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KRISHNA, C. JOSHI. "Fluorine containing Bioactive Heterocycles." Journal of Indian Chemical Society Vol. 63, Feb 1986 (1986): 187–90. https://doi.org/10.5281/zenodo.6253363.

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Department of Chemistry, University of Rajasthan, Jaipur-302 004 In recent decades, there has been considerable interest in medical applications and biochemistry of organic compounds containing fluorine. The discovery of 5-fluoronracil in the fifties is a classical example of a heterocyclic compound where the replacement of even one hydrogen by a fluorine atom led to great modification in biological activity of the parent non-fluorinated heterocycle. This presentation gives a background to this exciting new area in organic chemistry and briefly describes some of the recent work in the author&#

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Adak, Laksmikanta, and Tubai Ghosh. "Recent Progress in Iron-Catalyzed Reactions Towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles." Current Organic Chemistry 24, no. 22 (2020): 2634–64. http://dx.doi.org/10.2174/1385272824999200714102103.

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Heterocyclic compounds are the largely diverse organic molecules and find prevalent applications in the fine chemical industry, medicinal chemistry and agricultural science. They are also among the most commonly bearing frameworks in numerous drugs and pharmaceutical substances. Therefore, the development of convenient, efficient and environmentally benign methods to produce various types of heterocyclic compounds is an attractive area of research. For the synthesis and functionalization of heterocycles, enormous achievements have been attributed over the past decades. Recently, ironcatalyzed

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Banerjee, Bubun, and Gurpreet Kaur. "Microwave Assisted Catalyst-free Synthesis of Bioactive Heterocycles." Current Microwave Chemistry 7, no. 1 (2020): 5–22. http://dx.doi.org/10.2174/2213335607666200226102010.

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This review deals with the recent advances on the microwave-assisted synthesis of bioactive heterocycles without using any catalyst under various reaction conditions. Synthesis of various biologically promising N-heterocycles, O-heterocycles, S-heterocycles, N as well as O- or S-heterocycles reported so far under catalyst-free microwave-irradiated conditions are discussed in this review.

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Polshettiwar, Vivek, and Rajender S. Varma. "Greener and expeditious synthesis of bioactive heterocycles using microwave irradiation." Pure and Applied Chemistry 80, no. 4 (2008): 777–90. http://dx.doi.org/10.1351/pac200880040777.

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The utilization of green chemistry techniques is dramatically reducing chemical waste and reaction times as has recently been proven in several organic syntheses and chemical transformations. To illustrate these advantages in the synthesis of bioactive heterocycles, we have studied various environmentally benign protocols that involve greener alternatives. Microwave (MW) irradiation of neat reactants catalyzed by the surfaces of recyclable mineral supports, such as alumina, silica, clay, or their "doped" versions, enables the rapid one-pot assembly of heterocyclic compounds, such as flavonoids

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Palumbo Piccionello, Antonio. "Bioactive Oxadiazoles 2.0." International Journal of Molecular Sciences 23, no. 7 (2022): 3841. http://dx.doi.org/10.3390/ijms23073841.

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Pravinsing, S. Girase1 Bhikan J. Khairnar1 &. Bhata R. Chaudhari1 *2. "RECENT ADVANCES IN SYNTHESIS OF 2H-INDAZOLE FROM 2-SUBSTITUTED BENZALDEHYDE: A REVIEW." GLOBAL JOURNAL OF ENGINEERING SCIENCE AND RESEARCHES 6, no. 6 (2019): 178–91. https://doi.org/10.5281/zenodo.3262348.

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Several compounds has more than one nitrogen contained bicyclic heterocycles were important structural motifs found in numerous natural products and bioactive molecules. In recent years, the synthesis of bicyclic compounds possessing imidazole heterocycle as central core has been the focus of great interest. They are associated with diversified biological activities

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Jha, Mukund, Dani Youssef, Haley Sheehy, and Amitabh Jha. "Synthesis and Pharmacology of Clinical Drugs Containing Isoindoline Heterocycle Core." Organics 6, no. 1 (2025): 3. https://doi.org/10.3390/org6010003.

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Heterocyclic compounds are the cornerstone for active pharmaceutical ingredients. Among heterocycles, isoindoline core occupies a special place, as ten commercial bioactive compounds/drugs contain this skeleton decorated with several functional groups required for optimal receptor binding. These drugs are employed for indications such as multiple myeloma, leukemia, inflammation, hypertension, edema, obesity, and insect control. This review presents the pharmacological activities, mechanisms of action, and chemical syntheses of these commercial bioactive molecules/drugs.

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Palumbo Piccionello, Antonio. "Bioactive Oxadiazoles 3.0." International Journal of Molecular Sciences 25, no. 11 (2024): 6027. http://dx.doi.org/10.3390/ijms25116027.

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Sharma, Praveen Kumar, Andleeb Amin, and M. Kumar. "Synthetic Methods of Medicinally Important Heterocycles-thiazines: A Review." Open Medicinal Chemistry Journal 14, no. 1 (2020): 71–82. http://dx.doi.org/10.2174/1874104502014010071.

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Heterocyclic compounds containing N and S atoms have unique properties so that they can be used as potential reactive materials in pharmacokinetic systems. In medicinal chemistry, the therapeutic applications of nitrogen sulphur heterocycles are well known. Especially, Thiazines attract the attention of chemists due to their great bioactive behavior. The present study is a review of the work carried out by the research community for the synthesis of novel, effective, medicinally important heterocyclic compounds-thiazines.

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Dissertations / Theses on the topic "Bioactive Heterocycles"

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Agocs, Lisa Lynn. "Design of bioactive chalcogenobismuth(III) heterocycles." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq24728.pdf.

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Rai, B. "Synthesis of some bioactive oxygen and nitrogen heterocycles." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1993. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3080.

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Trippier, Paul Charles. "Synthesis of highly substituted heterocycles : the oxazolomycins." Thesis, University of Oxford, 2006. http://ora.ox.ac.uk/objects/uuid:b758987c-7a0c-4c1b-982c-61b4d383680a.

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This thesis is concerned with studies towards the total synthesis of a class of natural products - the oxazolomycins. Attention was focused on the left-hand side triene fragment and right-hand side lactam heterocyclic system. This thesis describes the synthesis of a racemic terminal phenyl analogue of oxazolomycin A and C, possessing the left-hand side triene geometry as required. A novel truncated pyridine analogue is also described. The molecules represent a racemic total synthesis of analogues of phthoxazolin A and inthomycins B and C. The synthesis is based upon a crucial Stille cross-coup

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Deshpande, S. R. "Synthetic studies in bioactive nitrogen, oxygen and sulfur heterocycles." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1991. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2997.

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Shabbir, Ghulam. "The synthesis and mechanism of formation of some bioactive heterocycles." Thesis, University of Hertfordshire, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365934.

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Kilburn, John Paul. "Novel solid-phase synthesis strategies for the preparation of heterocycles and guanidines." Thesis, Open University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247056.

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Pfeifer, Viktor. "Tritium and Deuterium Labelling of Bioactive Molecules Catalyzed by Metallic Nanoparticles." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS275/document.

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Cette thèse vise à développer de nouvelles méthodes efficaces pour incorporer des isotopes de l’hydrogène dans les molécules organiques complexes, après une introduction portant sur les applications et la synthèse des molécules marquées par le deutérium et tritium. Les méthodes permettant le marquage, par échange isotopique direct, d’hétérocycles azotés par des isotopes de l’hydrogène restent perfectibles, voire inexistantes dans certains cas, malgré la récurrence de ce type de sous-structures dans les molécules d’intérêt pharmacologique. Pour cette raison, la majeure partie de ce travail a co

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Mojally, Mariam. "DNA binding studies of fluorinated bioactive heterocyclic compounds." Thesis, Loughborough University, 2015. https://dspace.lboro.ac.uk/2134/16732.

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Fluorinated heterocyclic compounds have drug like properties and possess a valuable biological activity due to their rigid chemical structures and the high solubility profile. Novel fluorinated heteroarenes have been synthesised by SNAr reaction of a range of fluorinated arenes including pentafluoropyridine, hexafluorobenzene and pentafluorotoluene to introduce a range of groups specially nitriles, benzimidazole, carbazole and benzimidazole. A number of cyclization reactions have been investigated with the aim of forming polycyclic structures that could act as DNA intercalators. The synthesise

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Dey, Sourav. "Synthesis of bioactive organic heterocyclic compounds using novel catalysts." Thesis, University of North Bengal, 2022. http://ir.nbu.ac.in/handle/123456789/5160.

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Chan, Lai Chun. "Synthesis of novel heterocyclic constraints as probes for peptide bioactive conformation." Thesis, University of Bath, 1992. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303487.

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Books on the topic "Bioactive Heterocycles"

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Eguchi, Shoji. Bioactive heterocycles. Edited by Eguchi Shoji. Springer, 2006.

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Motohashi, Noboru, ed. Bioactive Heterocycles VI. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-79218-5.

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Khan, Mahmud Tareq Hassan, ed. Bioactive Heterocycles III. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-73402-4.

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Khan, Mahmud Tareq Hassan, ed. Bioactive Heterocycles IV. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-73404-8.

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Khan, Mahmud Tareq Hassan, ed. Bioactive Heterocycles V. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-73406-2.

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Motohashi, Noboru, ed. Bioactive Heterocycles VII. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00336-3.

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Eguchi, Shoji, ed. Bioactive Heterocycles I. Springer-Verlag, 2006. http://dx.doi.org/10.1007/11514725.

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Eguchi, Shoji, ed. Bioactive Heterocycles II. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-72592-3.

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Khan, Mahmud Tareq Hassan. Bioactive Heterocycles III. Springer-Verlag Berlin Heidelberg, 2007.

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Khan, Mahmud Tareq Hassan. Bioactive Heterocycles IV. Springer-Verlag Berlin Heidelberg, 2007.

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Book chapters on the topic "Bioactive Heterocycles"

1

Doustkhah, Esmail, and Fatemeh Majidi Arlan. "Synthesis of Bioactive Thioxoimidazolidinones, Oxazolidinones, Thioxothiazolidinones, Thiazolidinediones." In N-Heterocycles. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-0832-3_13.

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Mohd Nor, Siti Mariam, Zhengshuang Xu, and Tao Ye. "Bioactive Macrocyclic Natural Products." In Heterocycles in Natural Product Synthesis. Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527634880.ch16.

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Gharib, Ali. "Eco-Friendly Synthesis of Bioactive Heterocycles." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_3.

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Kawase, Masami, Hiroshi Sakagami, and Noboru Motohashi. "The Chemistry of Bioactive Mesoionic Heterocycles." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/7081_2007_096.

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Lamberth, Clemens, and Jürgen Dinges. "The Significance of Heterocycles for Pharmaceuticals and Agrochemicals*." In Bioactive Heterocyclic Compound Classes. Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.ch1.

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Lamberth, Clemens, and Jürgen Dinges. "The Significance of Heterocycles for Pharmaceuticals and Agrochemicals." In Bioactive Heterocyclic Compound Classes. Wiley-VCH Verlag GmbH & Co. KGaA, 2013. http://dx.doi.org/10.1002/9783527664450.ch1.

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Gunasekaran, Pethaiah, J. Carlos Menéndez, and Subbu Perumal. "Synthesis of Heterocycles Through Multicomponent Reactions in Water." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_1.

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Dandia, Anshu, Shyam L. Gupta, and Shuchi Maheshwari. "Molecular Iodine: Mild, Green, and Nontoxic Lewis Acid Catalyst for the Synthesis of Heterocyclic Compounds." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_10.

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Bhardwaj, Shipra, and K. L. Ameta. "Microwave Radiations: A Tool for the Synthesis of Heterocycles in an Ecofriendly Manner." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_11.

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Kumar, Sudesh, Prachi Rathi, K. L. Ameta, and Dharma Kishore. "Green Chemistry Approach Using Heterogeneous Catalysts in the Heterocyclic Synthesis." In Green Chemistry: Synthesis of Bioactive Heterocycles. Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_12.

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Conference papers on the topic "Bioactive Heterocycles"

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Kumari, Sonam, Renu Sharma, and Ruchi Bharti. "ZnO nanoparticles: A promosing greener catalytic approach for synthesis of bioactive heterocycles." In INTERNATIONAL CONFERENCE ON HUMANS AND TECHNOLOGY: A HOLISTIC AND SYMBIOTIC APPROACH TO SUSTAINABLE DEVELOPMENT: ICHT 2022. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0114413.

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Fruit, Corinne, Julien Godeau, Marine Harari, Sylvain Laclef, Vincent Levacher, and Thierry Besson. "Microwave-assisted C-H arylation of Quinazolin-4-one-type Precursors of Bioactive Heterocycles." In 1st International Electronic Conference on Medicinal Chemistry. MDPI, 2015. http://dx.doi.org/10.3390/ecmc-1-a004.

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Verdes, Anastasia, Elena Gorincioi, Lucian Lupascu, Gheorghe Duca, and Fliur Macaev. "Targeting the bioactive dihydropyrimidines by ecofriendly procedure of biginelli reaction: study case of monastrol." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab24.

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Biologically active compounds decorated with dihydropyridine moiety are counted amongst the numerous broad-spectrum therapeutic agents that explain the increasing role of this scaffold in rational drug design [1]. The Biginelli reaction is a multicomponent reaction of aldehyde, (thio)urea, and ß-ketoester, involving Mannich reaction in the first step, which produces multifunctionalized 3,4-dihydropyrimidin-2-(1H)-ones and related heterocyclic compounds [2]. The attractiveness of this acid-catalyzed one-pot condensation reaction lies in the simplicity of grafting the substituent into the struct

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