Academic literature on the topic 'Bioanalytical methods'

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Journal articles on the topic "Bioanalytical methods"

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Woltman, Steven J. "Bioanalytical methods." TrAC Trends in Analytical Chemistry 15, no. 5 (May 1996): VI. http://dx.doi.org/10.1016/0165-9936(96)80634-0.

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Skrzydlewska, Elżbieta. "Bioanalytical Methods in Toxicology." Toxicology Mechanisms and Methods 18, no. 6 (January 2008): 453. http://dx.doi.org/10.1080/15376510802156655.

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Hartmann, C., J. Smeyers-Verbeke, D. L. Massart, and R. D. McDowall. "Validation of bioanalytical chromatographic methods." Journal of Pharmaceutical and Biomedical Analysis 17, no. 2 (June 1998): 193–218. http://dx.doi.org/10.1016/s0731-7085(97)00198-2.

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Van Emon, Jeanette M. "Bioanalytical Methods for Food Contaminant Analysis." Journal of AOAC INTERNATIONAL 93, no. 6 (November 1, 2010): 1681–91. http://dx.doi.org/10.1093/jaoac/93.6.1681.

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Abstract Foods are complex mixtures of lipids, carbohydrates, proteins, vitamins, organic compounds, and other naturally occurring substances. Sometimes added to this mixture are residues of pesticides, veterinary and human drugs, microbial toxins, preservatives, contaminants from food processing and packaging, and other residues. This milieu of compounds can pose difficulties in the analysis of food contaminants. There is an expanding need for rapid and cost-effective residue methods for difficult food matrixes to safeguard our food supply. Bioanalytical methods are established for many food contaminants such as mycotoxins and are the method of choice for many food allergens. Bioanalytical methods are often more cost-effective and sensitive than instrumental procedures. Recent developments in bioanalytical methods may provide more applications for their use in food analysis.
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Labuda, Ján, Richard P. Bowater, Miroslav Fojta, Günter Gauglitz, Zdeněk Glatz, Ivan Hapala, Jan Havliš, et al. "Terminology of bioanalytical methods (IUPAC Recommendations 2018)." Pure and Applied Chemistry 90, no. 7 (July 26, 2018): 1121–98. http://dx.doi.org/10.1515/pac-2016-1120.

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AbstractRecommendations are given concerning the terminology of methods of bioanalytical chemistry. With respect to dynamic development particularly in the analysis and investigation of biomacromolecules, terms related to bioanalytical samples, enzymatic methods, immunoanalytical methods, methods used in genomics and nucleic acid analysis, proteomics, metabolomics, glycomics, lipidomics, and biomolecules interaction studies are introduced.
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Gleason, Carol R., Qin C. Ji, and Enaksha R. Wickremsinhe. "Evaluation of correlation between bioanalytical methods." Bioanalysis 12, no. 6 (March 2020): 419–26. http://dx.doi.org/10.4155/bio-2020-0019.

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Bioanalytical methods evolve throughout clinical development timelines, resulting in the need for establishing equivalency or correlation between different methods to enable comparison of data across different studies. This is accomplished by the conduct of cross validations and correlative studies to compare and describe the relationship. The incurred sample reanalysis acceptance criterion seems to be adopted universally for cross validations and correlative studies; however, this does not identify any trends or biases between the two methods (datasets) being compared. Presented here are graphing approaches suitable for comparing two methods and describing equivalence or correlation. This article aims to generate awareness on graphing techniques that can be adopted during cross validations and correlative studies.
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Heudi, Olivier. "Green bioanalytical methods are now a reality." Bioanalysis 4, no. 11 (June 2012): 1257. http://dx.doi.org/10.4155/bio.12.112.

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Wong, Yong Foo, Constanze Hartmann, and Philip J Marriott. "Multidimensional gas chromatography methods for bioanalytical research." Bioanalysis 6, no. 18 (September 2014): 2461–79. http://dx.doi.org/10.4155/bio.14.186.

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Babington, Ruth, Sonia Matas, M. Pilar Marco, and Roger Galve. "Current bioanalytical methods for detection of penicillins." Analytical and Bioanalytical Chemistry 403, no. 6 (April 10, 2012): 1549–66. http://dx.doi.org/10.1007/s00216-012-5960-4.

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TSUYAMA, Naohiro. "Visualization of Radiation Dose by Bioanalytical Methods." BUNSEKI KAGAKU 63, no. 6 (2014): 445–53. http://dx.doi.org/10.2116/bunsekikagaku.63.445.

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Dissertations / Theses on the topic "Bioanalytical methods"

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Cannan, Susan. "Microelectrode methods for bioanalytical and biophysical applications." Thesis, University of Warwick, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397013.

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Brown, Stacy D., and Tyler C. Melton. "Trends in Bioanalytical Methods for Club Drugs: 2000-2010." Digital Commons @ East Tennessee State University, 2011. https://doi.org/10.1002/bmc.1549.

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The term 'club drug' can be loosely defined as any substance used to enhance social settings. Such drugs are commonly found at raves or similar all-night dance parties and include methamphetamine, 3,4-methylenedioxymethamphetamine, gamma-hydroxybutyrate (GHB), ketamine (KET), and flunitrazepam (FLU). These drugs have potentially dangerous side effects including hallucinations, paranoia, amnesia and hyperthermia. In addition, GHB, KET and FLU are considered predatory drugs due to their roles in drug-facilitated sexual assault. Forensic and regulatory agencies routinely have the need for determination and accurate quantification of these drugs in biological fluids, especially in cases of mortality or criminal investigations. This review presents the chromatographic and spectroscopic methods published for such analyses over the last decade, including sample preparation techniques and validation data.
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Pihlblad, Alma. "Development and comparison of bioanalytical methods to measure free analyte." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-413669.

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Free analyte is measured to be able to understand the pharmacological effects of a drug in the body, the binding to its ligand, and the effective drug level among other things. Thereby, it is important with correct measurements of free analyte, although it is not that easy to achieve since overestimations can occur. In this project, several immunoassays were developed for the bioanalytical methods Gyrolab and ELISA to measure free analyte, where the biotherapeutics Avastin® and Lucentis®, and the ligand VEGF were used as analytes. One difference between the methods is the short contact time of just a few seconds for Gyrolab compared to the sample incubation time of a couple of hours for ELISA. One difference between the antibodies is that Lucentis is an affinity-matured Fab region, and therefore, has a stronger affinity to VEGF compared to Avastin. When free Avastin was measured, the difference was significant, with ELISA estimating higher concentrations compared to Gyrolab. However, this was not the case for all assays. In some cases, this was probably due to differences between the methods that could not be seen. Otherwise, the results with no difference between the methods, when measuring free analyte with Lucentis as the drug, were expected due to the stronger affinity and longer halftime of dissociation. However, the difference with the longer sample incubation time for ELISA compared to the short contact time for Gyrolab seems to influence the measurement of free analyte, depending on the affinity of the components being measured.
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Cai, Xiaohan. "¿¿¿¿¿¿Development of Bioanalytical Methods for Clinical Applications and Drug Screening." Cleveland State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=csu1314982525.

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Kunati, Sandeep Reddy. "DEVELOPMENT OF BIOANALYTICAL METHODS FOR QUANTITATIVE MEASUREMENT OF ANTICANCER AGENTS." Cleveland State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=csu1523439107242919.

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Deupree, Susan M. Schoenfisch Mark H. "Bioanalytical methods for investigating bacterial adhesion and the antibacterial action of nitric oxide." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2009. http://dc.lib.unc.edu/u?/etd,2314.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2009.
Title from electronic title page (viewed Jun. 26, 2009). " ... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry Biological Chemistry." Discipline: Chemistry; Department/School: Chemistry.
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Feng, Ye. "DEVELOPMENT OF QUANTITATIVE BIOANALYTICAL METHODS FOR THE PHARMACOLOGICAL STUDIES OF ANTI-CANCER DRUGS." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1392249778.

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Römsing, Susanne. "Development and Validation of Bioanalytical Methods : Application to Melatonin and Selected Anti-Infective Drugs." Doctoral thesis, Uppsala universitet, Analytisk kemi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-131519.

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This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. Developed methods were validated according to international guidelines. Melatonin is a hormone secreted by the pineal gland with a robust circadian rhythm. Bioanalytical methods for determination of melatonin in plasma and saliva have been developed which were used for monitoring melatonin levels in volunteers and patients suffering from sleep related diseases. Eflornithine (DFMO) is a chiral drug used for the treatment of human African trypanosomiasis. A bioanalytical method for determination of the DFMO enantiomers in plasma, after precolumn derivatization with o-phtalaldehyde and N-acetyl-L-cystein has been developed. The method has been used to study the L- and D-DFMO pharmacokinetics, in order to investigate the possible development of an oral treatment of DFMO. A method for simultaneous determination of three antiretroviral drugs i.e. Lamivudine (3TC), Zidovudine (AZT) and Nevirapine (NVP) in dried blood spots (DBS) was developed. The method was used for drug determination in two subjects after receiving standard antiretroviral treatment. The method seemed well suitable for the determination of 3TC and NVP and in some extent for AZT. Lumefantrine (LF) is one of the active components in a new fixed drug combination recommended by the WHO as a replacement to older drugs that has lost their effect. A method for the determination of LF in DBS was developed. The method is suitable for monitoring of drug treatment in rural settings. Tafenoquine is a new promising antimalarial drug under development. A method for the determination of Tafenoquine in plasma and in DBS is described. The method may be useful in future clinical studies in laboratory environment as well as in rural settings.
Felaktigt tryckt som Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 703
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Atherton, Adrian Ashley. "Nonlinear wave-mixing spectroscopic methods for bioanalytical and biophysical applications with sensitive detection at the single cell level." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2006. http://wwwlib.umi.com/cr/ucsd/fullcit?p3230037.

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Thesis (Ph. D.)--University of California, San Diego and San Diego State University, 2006.
Title from first page of PDF file (viewed November 17, 2006). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
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McCulloch, Melissa. "Development of Quantitative Bioanalytical Methods for the Measurement of Pharmaceutical Compounds via HPLC-UV and HPLC-MS/MS." Cleveland State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=csu1255046678.

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Books on the topic "Bioanalytical methods"

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High throughput bioanalytical sample preparation: Methods and automation strategies. Amsterdam: Elsevier, 2003.

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Christine T. C. Fook Sheung. The applicability of ASTED/HPLC to the development of bioanalytical methods. Leicester: De Montfort University, 1996.

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Barceló, Damià. Biosensors for the environmental monitoring of aquatic systems: Bioanalytical and chemical methods for endocrine disruptors. Dordrecht: Springer, 2009.

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Methods of Biochemical Analysis: Bioanalytical Instrumentation. Wiley-Interscience, 1993.

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Wells, David Ames. High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies. Elsevier, 2020.

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Wells, David Ames, and Wells David. High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies. Elsevier Science & Technology Books, 2003.

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Cass, Quezia B., Gabriella Massolini, Enrica Calleri, and Carmen Lucia Cardoso, eds. Advances in Bioanalytical Methods for Probing Ligand-Target Interactions. Frontiers Media SA, 2020. http://dx.doi.org/10.3389/978-2-88963-818-5.

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High Throughput Bioanalytical Sample Preparation - Methods and Automation Strategies. Elsevier, 2003. http://dx.doi.org/10.1016/s1464-3456(03)x8001-1.

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Van Emon, Jeanette M., 1956-, ed. Immunoassay and other bioanalytical techniques. Boca Raton: CRC Press/Taylor & Francis, 2007.

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Emon, Jeanette M. van. Immunoassay and Other Bioanalytical Techniques. CRC, 2006.

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Book chapters on the topic "Bioanalytical methods"

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Stead, Sara, and Jacques Stark. "Bioanalytical Screening Methods." In Chemical Analysis of Antibiotic Residues in Food, 153–86. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118067208.ch5.

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Rup, Bonita, Corinna Krinos-Fiorotti, Boris Gorovits, and Hendrik Neubert. "Bioanalytical Methods and Immunogenicity Assays." In Biophysical Methods for Biotherapeutics, 207–42. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9781118354698.ch8.

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Loos, Walter J., Peter de Bruijn, and Alex Sparreboom. "Bioanalytical Methods in Clinical Drug Development." In Principles of Anticancer Drug Development, 63–86. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-7358-0_3.

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Karnes, H. Thomas, and Kumar A. Shah. "Validation and Control of Bioanalytical Methods." In Cancer Drug Discovery and Development, 117–39. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9135-4_8.

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Wagmann, Lea, and Hans H. Maurer. "Bioanalytical Methods for New Psychoactive Substances." In New Psychoactive Substances, 413–39. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/164_2017_83.

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Gupta, M. N., and B. Mattiasson. "Unique Applications of Immobilized Proteins in Bioanalytical Systems." In Methods of Biochemical Analysis, 1–34. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/9780470110577.ch1.

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Powell, Mark L., and Steve E. Unger. "Bioanalytical Methods: Challenges and Opportunities in Drug Development." In Applications of Pharmacokinetic Principles in Drug Development, 21–52. Boston, MA: Springer US, 2004. http://dx.doi.org/10.1007/978-1-4419-9216-1_2.

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Ambardekar, Vishakha V., and Stephan T. Stern. "NBCD Pharmacokinetics and Bioanalytical Methods to Measure Drug Release." In Non-Biological Complex Drugs, 261–87. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-16241-6_8.

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Chagas, Cyro L. S., Thiago M. G. Cardoso, and Wendell K. T. Coltro. "Paper-Based Electrophoresis Microchip as a Powerful Tool for Bioanalytical Applications." In Methods in Molecular Biology, 133–42. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-8964-5_10.

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Karnes, H. Thomas. "Validation and Control of Bioanalytical Methods in Clinical Drug Development." In Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 91–110. Totowa, NJ: Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-734-5_7.

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Conference papers on the topic "Bioanalytical methods"

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Narayanan, Narasimhachari, Garrick Little, Ramesh Raghavachari, and Gabor Patonay. "New near-infrared dyes for applications in bioanalytical methods." In Photonics West '95, edited by Joseph R. Lakowicz. SPIE, 1995. http://dx.doi.org/10.1117/12.208471.

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Lin, Hao, Rajiv Bharadwaj, Juan G. Santiago, and Bijan Mohammadi. "A High-Fidelity Electrokinetic Flow Model for the Prediction of Electrophoregrams in On-Chip Eletrophoresis Applications." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-79439.

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On-chip electrophoresis is a growing field with increasing chemical and bioanalytical applications such as genomics and proteomics. The use of multicomponent and heterogeneous electrolyte configurations can often lead to complex flow behavior. In this work, we present a high-fidelity, low computational cost electrokinetic flow model for the modeling and optimization of electrophoretic separations. The model adopts a depth-averaged approach that captures convective-dispersion processes, and includes important physical effects such as electrical body force and fully nonlinear multi-species electromigration. The corresponding numerical scheme is based on a finite volume approach using a monotonic upstream-centered construction (MUSCL). The numerical model can simulate arbitrary electrolyte and sample configurations, and capture the complex evolution of sharp, narrow sample peaks and high pre-concentration (stacking) ratios. Exemplary results showing both field amplified sample stacking and isotachophoresis processes are presented. The development of such models is critical to the efficient design and optimization of on-chip CE methods and devices.
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