Relevant bibliographies by topics / Bioassay-guided fractionation

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Bioassay-guided fractionation'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 January 2023

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Journal articles on the topic "Bioassay-guided fractionation"

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Niu, Siwen, Dong Liu, Zongze Shao, Peter Proksch, and Wenhan Lin. "Eutypellazines A–M, thiodiketopiperazine-type alkaloids from deep sea derived fungus Eutypella sp. MCCC 3A00281." RSC Advances 7, no. 53 (2017): 33580–90. http://dx.doi.org/10.1039/c7ra05774a.

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Verma, Ankita, B. N. Johri, and Anil Prakash. "Antagonistic Evaluation of Bioactive Metabolite from Endophytic Fungus, Aspergillus flavipes KF671231." Journal of Mycology 2014 (August 27, 2014): 1–5. http://dx.doi.org/10.1155/2014/371218.

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Of the total 40 endophytic fungi isolated from foliar tissues of medicinal plant Stevia rebaudiana Bertoni, a fungal isolate, Aspergillus flavipes, was subjected to bioassay guided fractionation. The fractionation was found active against medicinal plant pathogen Sclerotinia sclerotiorum with an inhibition zone of 29 mm in size. Further the metabolite was extracted which shows 20% growth inhibition in 24 h and 46% after 48 h, respectively. Bioassay guided chemical compound was identified as 1,2-benzenedicarboxylic acid, mono(2-ethylhexyl) ester. On the basis of morphological characters and rDN
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Uhlig, Silvio, Helene Wisløff, and Dirk Petersen. "Identification of Cytotoxic Constituents ofNarthecium ossifragumUsing Bioassay-Guided Fractionation." Journal of Agricultural and Food Chemistry 55, no. 15 (2007): 6018–26. http://dx.doi.org/10.1021/jf070776k.

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Li, Yong, Dong Liu, Zhongbin Cheng, Peter Proksch, and Wenhan Lin. "Cytotoxic trichothecene-type sesquiterpenes from the sponge-derived fungus Stachybotrys chartarum with tyrosine kinase inhibition." RSC Advances 7, no. 12 (2017): 7259–67. http://dx.doi.org/10.1039/c6ra26956g.

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López-Ogalla, Javier, Esther García-Palomero, Jorge Sánchez-Quesada, et al. "Bioactive prenylated phenyl derivatives derived from marine natural products: novel scaffolds for the design of BACE inhibitors." MedChemComm 5, no. 4 (2014): 474–88. http://dx.doi.org/10.1039/c3md00236e.

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Bioassay guided-fractionation of active extracts from the sponge Sarcotragus sp. led to the isolation biochemical characterization and development of a chemistry program of bioactive prenylated phenyl derivatives.
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Kim, Gyoung-Deuck, Jin Lee, and Joong-Hyuck Auh. "Metabolomic Screening of Anti-Inflammatory Compounds from the Leaves of Actinidia arguta (Hardy Kiwi)." Foods 8, no. 2 (2019): 47. http://dx.doi.org/10.3390/foods8020047.

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The metabolomic screening of potential anti-inflammatory compounds in the leaves of Actinidia arguta was performed by using LC-MS/MS. Ethanol extracts were prepared, and the anti-inflammatory effects were investigated based on nitric oxide (NO) synthesis and inducible nitric oxide synthase expression in lipopolysaccharide-induced RAW 264.7 macrophages. The 75% ethanol extract showed the highest inhibitory effect on nitric oxide (NO) production, and it was further separated by in vitro bioassay-guided fractionation using preparative LC with reversed-phase column separation. Through multiple ste
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Matos Lopes, Tamyris Regina, Fábio Rodrigues de Oliveira, Flávia Filocreão Malheiros, Marcieni Ataíde de Andrade, Marta Chagas Monteiro, and Ana Cristina Baetas Gonçalves. "Antimicrobial bioassay-guided fractionation of a methanol extract ofEupatorium triplinerve." Pharmaceutical Biology 53, no. 6 (2014): 897–903. http://dx.doi.org/10.3109/13880209.2014.948634.

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Finger, Daiane, Christiane Schinieder Machado, Yohandra Reyes Torres, et al. "Antifungal Bioassay-Guided Fractionation of an Oil Extract of Propolis." Journal of Food Quality 36, no. 5 (2013): 291–301. http://dx.doi.org/10.1111/jfq.12039.

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Melariri, Paula, William Campbell, Paschal Etusim, and Peter Smith. "Antiplasmodial Properties and Bioassay-Guided Fractionation of Ethyl Acetate Extracts fromCarica papayaLeaves." Journal of Parasitology Research 2011 (2011): 1–7. http://dx.doi.org/10.1155/2011/104954.

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We investigated the antiplasmodial properties of crude extracts fromCarica papayaleaves to trace the activity through bioassay-guided fractionation. The greatest antiplasmodial activity was observed in the ethyl acetate crude extract.C. papayashowed a high selectivity forP. falciparumagainst CHO cells with a selectivity index of 249.25 and 185.37 in the chloroquine-sensitive D10 and chloroquine-resistant DD2 strains, respectively.Carica papayaethyl acetate extract was subjected to bioassay-guided fractionation to ascertain the most active fraction, which was purified and identified using high-
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Shahbazi, Behzad, Saba Feyzmand, Fataneh Jafari, et al. "Antidiabetic Potential of Prosopis farcta Roots: In Vitro Pancreatic Beta Cell Protection, Enhancement of Glucose Consumption, and Bioassay-Guided Fractionation." Evidence-Based Complementary and Alternative Medicine 2020 (January 20, 2020): 1–9. http://dx.doi.org/10.1155/2020/8048273.

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By using the streptozotocin- (STZ-) induced cytotoxicity in β-TC3 cells as an assay model, a bioassay-guided fractionation study was employed to isolate and characterize the potential antidiabetic principles of roots of Prosopis farcta. A combination of open column chromatography on reverse-phase silica gel using a water-ethanol gradient (10 : 90 to 100 : 0) followed by HPLC-based fractionation led to an active compound that appears to be composed of carbohydrate/sugar. When cell viability under STZ was reduced to 49.8 ± 4% (mean ± SD), treatment with the active compound at the concentration o
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Dissertations / Theses on the topic "Bioassay-guided fractionation"

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Mianda, Mutombo Sephora. "Isolation of antiplasmodial naphthylisoquinoline alkaloids from Ancistrocladus sp. through bioassay-guided fractionation." Diss., University of Pretoria, 2019. http://hdl.handle.net/2263/77853.

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Ancistrocladus is the only genus in the Ancistrocladaceae family and together with the closely related Dioncophyllaceae, they produce naphthylisoquinoline (NIQ) alkaloids. This class of compounds exhibits a very interesting large spectrum of bioactivities. Some of these compounds have shown very promising antiplasmodial activity. Leaves of an as yet unidentified Ancistrocladus sp collected in the region of Bonsolerive (Northwestern part of DRC), were investigated for their antiplasmodial activity. They were air dried at room temperature and ground. The ground plant material was extracted seque
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Jia, Xuegang. "Optimization methods for analytical separations : MALDI, dynamic IEF and bioassay guided fractionation /." Available to subscribers only, 2008. http://proquest.umi.com/pqdweb?did=1650505471&sid=13&Fmt=2&clientId=1509&RQT=309&VName=PQD.

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Mokwelu, Onyinye Vivian. "Bioassay guided fractionation of Angiotensin converting enzyme inhibitor compound from Hypericum perforatum." University of the Western Cape, 2019. http://hdl.handle.net/11394/6975.

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Magister Pharmaceuticae - MPharm<br>Due to the contribution of hypertension to various cardiovascular diseases, many studies are currently focused on identifying efficient bioactive compounds with antihypertensive activity and thus reducing the levels of cardiovascular disease. ACE inhibitors are an important component of the therapeutic regimen for treating hypertension, but due to the increase in the prevalence of side effects of synthetic compounds, alternative and complementary medicines which may consist of pure bioactive compound or a combination of various compounds from natural sources
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Abrahams, Meryl Arlene. "Bioassay-guided fractionation of Artemisia afra for in vitro antimalarial activity against Plasmodium falciparum." Master's thesis, University of Cape Town, 1997. http://hdl.handle.net/11427/26263.

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With the increase in recent years in the prevalence of malaria, and in drug resistance of Plasmodium falciparum, there has been much interest in natural plant products for new antimalarials with novel modes of action against Plasmodium. Artemisinin or Qinghaosu is one such antimalarial isolated from a Chinese herb, Anemisia annua (Asteraceae) and it is currently undergoing phase I and II clinical trials. The Southern African species, Artemisia afra (African wormwood, wildeals, lengana) is commonly used by local traditional healers for symptoms of malaria, in particular fever. Thus it seemed ap
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Sevak, Hamel P. "Potential chemical defenses against diatom fouling in macroalgae from the Antarctic Peninsula insights from bioassay guided fractionation /." Birmingham, Ala. : University of Alabama at Birmingham, 2010. https://www.mhsl.uab.edu/dt/2009m/sevak.pdf.

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Wilson, Shannon Courtney. "Applications and Advancements of Dynamic Isoelectric Focusing." OpenSIUC, 2014. https://opensiuc.lib.siu.edu/dissertations/865.

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The work in the dissertation expands the applications of DIEF and describes the development of incorporating DIEF in a microfluidic chip to create a comprehensive proteomics tool. Proof-of-concept DIEF experiments have been done previously, so the focus of this work is to explore the capabilities of DIEF. Dynamic isoelectric focusing (DIEF) is a separation technique invented by Dr. Luke Tolley. It is similar to capillary isoelectric focusing except it uses four high voltage electrodes to form a pH gradient instead of only two. The additional two electrodes are able to manipulate the pH gra
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Segopa, Ellen Kelebogile. "Marine bacteria as a potential source for novel antimicrobial compounds." University of the Western Cape, 2021. http://hdl.handle.net/11394/7918.

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>Magister Scientiae - MSc<br>The high rate of rediscovery of known compounds has led to a decline in the discovery of novel natural products. The high biodiversity of organisms growing in extreme conditions such as oceans has led to the increased interest by researchers for their use as a source of novel natural products. Marine bacteria are known for their extensive biosynthetic capacity to produce diverse natural products, which are suitable for various biotechnology applications such as in agriculture, for treatment of fungal plant pathogens, and as antibiotics, for treatment of bacterial i
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Marion, Zachary Harrison. "Ecological efficacy of chemically-mediated antipredator defenses in the Eastern newt Notophthalmus viridescens." Thesis, Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/34856.

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Frogs, toads, and salamanders are well known for harboring an array of distasteful (and poisonous) secondary metabolites, presumably as antipredator defenses; yet few experiments have rigorously demonstrated the efficacy of amphibian chemical defenses against ecologically relevant consumers. For example, despite an absence of rigorous statistical evidence showing their distastefulness to predators, eastern newts (Notophthalmus viridescens (Rafinesque))--a common salamander in lentic North American habitats--are assumed to tolerate diverse predator assemblages because newts secrete tetrodotoxin
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Neves, Michelline Viviane Marques das. "Fracionamento biomonitorado da própolis vermelha de Igarassu, Pernambuco, Brasil." Universidade Federal da Paraí­ba, 2014. http://tede.biblioteca.ufpb.br:8080/handle/tede/6840.

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Made available in DSpace on 2015-05-14T13:00:09Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 6176997 bytes, checksum: 84882ba9517a6db053cc7c655b0e9d39 (MD5) Previous issue date: 2014-08-25<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>Propolis is an heterogeneous mixture of substances, produced by melliferous bees from plants in close proximity with the bee´s hives. It is usually classified according to its botanical origin and chemical composition that vary according to geographical origin. Studies have shown that red propolis have physicochemical and biol
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Segopa, Ellen Kelebogile. "Marine bacteria as a potential source for novel antimicrobial compounds." University of the Western Cape, 2020. http://hdl.handle.net/11394/7828.

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>Magister Scientiae - MSc<br>The high rate of rediscovery of known compounds has led to a decline in the discovery of novel natural products. The high biodiversity of organisms growing in extreme conditions such as oceans has led to the increased interest by researchers for their use as a source of novel natural products. Marine bacteria are known for their extensive biosynthetic capacity to produce diverse natural products, which are suitable for various biotechnology applications such as in agriculture, for treatment of fungal plant pathogens, and as antibiotics, for treatment of bacterial i
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Book chapters on the topic "Bioassay-guided fractionation"

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Bulloch, Daryl, Ramon Lavado, and Daniel Schlenk. "Bioassay Guided Fractionation (Toxicity Identification and Evaluation) for the Determination of Estrogenic Agents in Environmental Samples." In ACS Symposium Series. American Chemical Society, 2010. http://dx.doi.org/10.1021/bk-2010-1048.ch026.

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Conference papers on the topic "Bioassay-guided fractionation"

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Jambwa, P., F. N. Makhubu, S. M. Nkadimeng, G. Matope, G. Fouche, and L. J. McGaw. "Bioassay guided fractionation of Senna singueana and its potential for development of poultry phytogenic feed additives." In GA – 69th Annual Meeting 2021, Virtual conference. Georg Thieme Verlag, 2021. http://dx.doi.org/10.1055/s-0041-1736818.

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