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Dissertations / Theses on the topic 'Bioassays in vitro'

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Published: 4 June 2021

Last updated: 8 February 2022

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1

Zhang, Yanling 1955. "Development of in vitro bioassays for determination of salinity tolerance in potato (Solanum spp.)." Thesis, McGill University, 1998. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35659.

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Salinity problems seriously affect agricultural production by reducing crop yield and arable land. The evaluation of potato genotypes (Solanum spp.) for their salinity (NaCl) tolerance in conventional field trials is time consuming and labour intensive. The results are often confounded by many field and environmental variations. In vitro bioassays can overcome some of these difficulties by providing faster, more convenient and dependable methods for screening and selection of salt tolerant potato genotypes. The objective of this research was to develop in vitro bioassay methods for screening a

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2

Zhang, Yanling. "Development of in vitro bioassays for determination of salinity tolerance in potato (Solanum spp.)." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0017/NQ44645.pdf.

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3

Berkelind, Ellinor. "In vitro bioassays for toxicity testing of wastewater - an evaulation of different sample treatment techniques." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-412525.

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4

Wang, Ruxi [Verfasser], and Andreas [Akademischer Betreuer] Hensel. "Bioassays guided in vitro investigations on skin active plants from traditional Chinese medicine / Ruxi Wang. Betreuer: Andreas Hensel." Münster : Universitäts- und Landesbibliothek der Westfälischen Wilhelms-Universität, 2012. http://d-nb.info/1027021069/34.

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5

Iji, Oluwafikemi Temitayo. "In vitro bioassays as tools for evaluating toxicity of acidic drainage from a coal mine in Mpumalanga, South Africa." Thesis, University of Pretoria, 2016. http://hdl.handle.net/2263/60126.

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Coal mining and coal utilization in Mpumalanga have increased over the years due to national reliance on coal as a source of power generation. In general, this has caused significant deterioration of water quality wherever streams are impacted by acid mine drainage (AMD). The aim of this research was to assess the use of in vitro bioassays as a complement to, or potential future replacement of, waste effluent testing in whole animals from AMD impacted watersheds subjected to passive and active treatment, correlating observed changes with water chemistry analysis. To accomplish this goal, water

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6

Liefooghe, Emily Claire. "Studies on the specificities of in vivo and in vitro bioassays used in the potency determination of therapeutic erythropoietin." Thesis, Open University, 2006. http://oro.open.ac.uk/54864/.

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Erythropoietin (Epo), a kidney-produced cytokine, promotes the proliferation and differentiation of erythroid progenitors into mature red blood cells. The <i>in vivo</i> biological activity of Epo is dependent on it being adequately glycosylated. Glycosylation is a variable process and its precise effect on clearance mechanisms within the body has yet to be fully established. Studies have shown, however, that the loss of the terminal sialic acid residue, leading to exposure of the penultimate galactose residue, results in a dramatic reduction in activity, owing to the liver's galactose-depende

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7

Clarke, Rachel Sarah. "Investigation of the biological effects of mixtures of man-made and natural chemical food contaminants using in vitro bioassays." Thesis, Queen's University Belfast, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.695302.

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Mycotoxins, heavy metals and pesticides are ubiquitous in the environment, contributing to multiple contamination of foodstuff. However, due to complications of determining their combined toxicity, legal limits of exposure are determined for single compounds, based on long standing toxicological techniques. Governmental regulatory bodies must begin to contemplate how to safeguard the population when such mixtures of contaminants are present in food. The aim of this thesis was to study the interactive and cytotoxic effects .of mixtures of chemical food contaminants when present at their corresp

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8

Alles, Gabriela Cristina. "Análise do potencial de Bacillus thuringiensis como agente de controle de Spdoptera frugiperda (Lepidoptera, Noctuidae) e Ostrinia nubilalis (Lepidoptera, Pyralidae)." Universidade do Vale do Rio dos Sinos, 2012. http://www.repositorio.jesuita.org.br/handle/UNISINOS/3662.

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Submitted by Mariana Dornelles Vargas (marianadv) on 2015-05-26T13:54:04Z No. of bitstreams: 1 analise_potencial.pdf: 1430284 bytes, checksum: 12436295c40ce78cf9c53abb0f1e16e3 (MD5)<br>Made available in DSpace on 2015-05-26T13:54:04Z (GMT). No. of bitstreams: 1 analise_potencial.pdf: 1430284 bytes, checksum: 12436295c40ce78cf9c53abb0f1e16e3 (MD5) Previous issue date: 2012-10-26<br>CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>A bactéria Bacillus thuringiensis exibe alta atividade tóxica específica para insetos devido à sintese de delta-endotoxinas, codificadas po

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9

Ngcobo, Silindile. "The suitability of estrogen and androgen bioassays for the measurement of endocrine activity in different water matrices." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/63041.

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Endocrine disrupting chemicals (EDCs) are ubiquitous in the environment and their presence in water bodies is documented. They discharge into surface water (SW) unmonitored, posing a threat to both aquatic and terrestrial lives. This is a challenge as not all populations have access to treated drinking water (TDW). The EDC contaminated serves as a route of exposure, together with ineffective treatment plants. Given the complexity of the endocrine system, EDCs may mimic or antagonise natural hormones or disrupt their synthesis, metabolism and excretion. The associated health effects incl

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10

Wyrepkowski, Claudia Dantas Comandolli. "Avaliação anti-leishmania in vitro e in vivo de Libidibia ferrea e estudo de formulações tópicas para o tratamento da forma cutânea da Leishmaniose." Universidade Federal do Amazonas - Instituto Nacional de Pesquisas da Amazônia, 2016. http://tede.ufam.edu.br/handle/tede/5133.

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Submitted by Izabel Monteiro (izabel_22@hotmail.com) on 2016-08-03T15:01:33Z No. of bitstreams: 1 Tese - Claudia Dantas Comandolli Wyrepkowski.pdf: 5493553 bytes, checksum: 2facc8046c9c0fe6bc72cf077d977196 (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-08-17T15:41:32Z (GMT) No. of bitstreams: 1 Tese - Claudia Dantas Comandolli Wyrepkowski.pdf: 5493553 bytes, checksum: 2facc8046c9c0fe6bc72cf077d977196 (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-08-1

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11

Souton, Emilie. "Utilisation de biotests in vitro, en complément d’analyses chimiques, pour l’évaluation du danger lié aux matériaux papiers-cartons recyclés destinés au contact alimentaire." Thesis, Bourgogne Franche-Comté, 2017. http://www.theses.fr/2017UBFCK057.

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Les matériaux au contact des aliments (MCDA) constituent un enjeu majeur pour les industriels européens de l’alimentation et de l’emballage d’autant que les MCDA doivent être produits selon les bonnes pratiques de fabrication et être en accord avec les règlementations, notamment le règlement cadre européen 1935/2004. Les MCDA constituent une source potentielle de contamination des aliments car ils peuvent transférer des constituants aux aliments par migration. Parmi les MCDA, les matériaux papiers-cartons sont les plus utilisés après les matériaux plastiques et leur taux de recyclage en Europe

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12

Schiwy, Andreas Herbert [Verfasser], Henner [Akademischer Betreuer] Hollert, and Andreas [Akademischer Betreuer] Schäffer. "The nanotoxicology of a newly developed zero-valent iron nanomaterial for groundwater remediation and its remediation efficiency assessment combined with in vitro bioassays for detection of dioxin-like environmental pollutants / Andreas Herbert Schiwy ; Henner Hollert, Andreas Schäffer." Aachen : Universitätsbibliothek der RWTH Aachen, 2016. http://d-nb.info/1130792668/34.

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13

Janer, Eleonor Adega Castro. "Resistência de Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) a fipronil: Padronização de bioensaios in vitro, detecção de resistência em populações de campo e avaliação sobre resistência cruzada com outras drogas." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-17012011-113819/.

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Para o sucesso das estratégias de manejo de Rhipicephalus (Boophilus) microplus (carrapato bovino) são necessários testes práticos, econômicos e confiáveis que possam detectar a presença de fenótipos resistentes a drogas em suas populações. O fipronil é um acaricida de uso relativamente recente não havendo testes padronizados para o diagnóstico de resistência do carrapato à molécula. No presente trabalho, foram padronizados bioensaios in vitro para esta finalidade: Teste de Imersão de Adultas, Teste de Imersão de Larvas e Teste de Pacote com Larvas. Os testes foram aplicados e, de forma inédit

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14

Gardia-Parège, Caroline. "Développement et applications de l'analyse dirigée par l'effet pour la recherche et l'identification de contaminants à risque pour les écosystèmes aquatiques." Thesis, Bordeaux, 2015. http://www.theses.fr/2015BORD0063/document.

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Les méthodes actuellement disponibles pour la surveillance de la qualité du milieu se réfèrent au suivi de composés définis par les réglementations et ne permettent pas d’appréhender l’(éco)toxicité réelle de tous les composés présents dans l’environnement (e.g. composés inconnus, produits de transformation, effets de mélange…). Dans ce contexte, une méthode d’analyse pluridisciplinaire intégrative, l’analyse dirigée par l’effet (EDA), a été développée. Cette approche bio-analytique vise à établir un lien de causalité entre une exposition aux contaminants et l’effet biologique observé. La déma

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15

Martínez, Gómez Concepción. "Sublethal effects of chemical pollution in benthic fish species from marine Spanish waters." Doctoral thesis, Universidad de Alicante, 2013. http://hdl.handle.net/10045/36264.

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16

Fuster, Laura. "Mise en oeuvre d’une démarche intégrée pour identifier des contaminants pertinents dans l’environnement." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0880/document.

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De nos jours, l’évaluation de la qualité d’un milieu naturel repose traditionnellement sur des analyses ciblant des molécules déjà connues pour être biologiquement actives. Cependant ces molécules ne reflètent que partiellement les effets biologiques observés et la complexité des matrices environnementales. Par ailleurs, les contaminants dans l’environnement subissent des phénomènes de dégradation (hydrolyse, biodégradation, photodégradation). Ces processus peuvent conduire à la génération de produits de transformation qui sont encore trop peu pris en compte dans l’évaluation du risque, alors

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17

Burbridge, Deborah Kate. "The development and use of an in vitro bioassay for pituitary growth hormone." Thesis, University of Sussex, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244321.

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18

Abrahams, Meryl Arlene. "Bioassay-guided fractionation of Artemisia afra for in vitro antimalarial activity against Plasmodium falciparum." Master's thesis, University of Cape Town, 1997. http://hdl.handle.net/11427/26263.

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With the increase in recent years in the prevalence of malaria, and in drug resistance of Plasmodium falciparum, there has been much interest in natural plant products for new antimalarials with novel modes of action against Plasmodium. Artemisinin or Qinghaosu is one such antimalarial isolated from a Chinese herb, Anemisia annua (Asteraceae) and it is currently undergoing phase I and II clinical trials. The Southern African species, Artemisia afra (African wormwood, wildeals, lengana) is commonly used by local traditional healers for symptoms of malaria, in particular fever. Thus it seemed ap

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19

Zhang, Weicheng. "Prediction of the skin sensitization potential of organic chemicals through in vitro bioassay and chemoassay information." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2015. http://nbn-resolving.de/urn:nbn:de:bsz:105-qucosa-161710.

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Skin sensitization resulting for allergic contact dermatitis (ACD) is an occupational and environmental health issue. The allergic hazard for workers and consumers is a serious problem for individuals, employers and marketing certain products. Consequently, it is necessary to accurately identify chemicals skin sensitization potential. According to the new EU chemical regulation REACH (Registration, Evaluation, Authorization and Restriction of Chemicals), information of skin sensitization of chemicals manufactured or imported at or above 1 ton/year should be available. Currently, valid approach

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20

Kotze, Danelle. "Production and pharmacological analysis of microcultures of Pelargonium sidoides DC and Pelargonium reniforme Curtis." Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/18115.

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21

Laqua, Anja. "Reaktive Toxizität in vitro." Doctoral thesis, Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2014. http://nbn-resolving.de/urn:nbn:de:bsz:105-qucosa-132574.

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Es wird eine Bioassay-Analyse von 168 Testsubstanzen gegenüber Tetrahymena pyriformis beschrieben. Mithilfe dieses In-vitro-Ansatzes konnte eine erste prognostische Aussage über die toxische Wirkung unbekannter Stoffe getroffen werden. Aus den Konzentrations-Wirkungs-Beziehungen erfolgte eine Bestimmung der Toxizitätserhöhung gegenüber der Narkoselevel-Toxizität. Dadurch war eine mechanistische Interpretation der Wirkstärke der Fremdstoffe möglich. Die Wirkung der Fremdstoffe basiert auf direkten toxikologisch relevanten Reaktionsmechanismen mit nukleophilen Biomolekülen oder nach entsprechend

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22

GABURO, JANETE C. G. "Desenvolvimento de um metodo de bioanalise in vitro para a determinacao de torio natural incorporado." reponame:Repositório Institucional do IPEN, 1989. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10214.

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Made available in DSpace on 2014-10-09T12:36:05Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T13:59:36Z (GMT). No. of bitstreams: 1 03641.pdf: 1524540 bytes, checksum: 9eac945221973ca315eb33b118d750af (MD5)<br>Dissertacao (Mestrado)<br>IPEN/D<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN/CNEN-SP

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Eichbaum, Kathrin Verfasser], Henner [Akademischer Betreuer] [Hollert, and Andreas [Akademischer Betreuer] Schäffer. "In vitro bioassay tools for the toxicological evaluation of dioxins and dioxin-like compounds in sediments and biota / Kathrin Eichbaum ; Henner Hollert, Andreas Schäffer." Aachen : Universitätsbibliothek der RWTH Aachen, 2016. http://d-nb.info/1130326551/34.

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24

Eichbaum, Kathrin [Verfasser], Henner [Akademischer Betreuer] Hollert, and Andreas [Akademischer Betreuer] Schäffer. "In vitro bioassay tools for the toxicological evaluation of dioxins and dioxin-like compounds in sediments and biota / Kathrin Eichbaum ; Henner Hollert, Andreas Schäffer." Aachen : Universitätsbibliothek der RWTH Aachen, 2016. http://nbn-resolving.de/urn:nbn:de:hbz:82-rwth-2016-009703.

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Laqua, Anja [Verfasser], Gerrit [Akademischer Betreuer] Schüürmann, Gerrit [Gutachter] Schüürmann, and Thomas [Gutachter] Braunbeck. "Reaktive Toxizität in vitro : Bioassay-Analyse organischer Elektrophile und Proelektrophile mit den Ciliaten Tetrahymena pyriformis / Anja Laqua ; Gutachter: Gerrit Schüürmann, Thomas Braunbeck ; Betreuer: Gerrit Schüürmann." Freiberg : Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2014. http://d-nb.info/1220837482/34.

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26

Bao, Weier. "The study of in vitro superfused spiral modiolar artery bioassay on the endothelin-1 antagonistic activity of (+)-myriceric acid a and its novel synthetic tetracyclic terpenoids intermediates." Thesis, Manhattan, Kan. : Kansas State University, 2010. http://hdl.handle.net/2097/4123.

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27

Zhang, Weicheng [Verfasser], Gerrit [Akademischer Betreuer] Schüürmann, Gerrit [Gutachter] Schüürmann, Wolfgang [Gutachter] Voigt, and Monika [Gutachter] Mazik. "Prediction of the skin sensitization potential of organic chemicals through in vitro bioassay and chemoassay information / Weicheng Zhang ; Gutachter: Gerrit Schüürmann, Wolfgang Voigt, Monika Mazik ; Betreuer: Gerrit Schüürmann." Freiberg : Technische Universitaet Bergakademie Freiberg Universitaetsbibliothek "Georgius Agricola", 2015. http://d-nb.info/1220912050/34.

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28

Masango, Mxolisi Goodwill. "A comparative analysis of the cytotoxicity of cyanotoxins using in vitro (cell culture) and in vivo (mouse) assays." Diss., Pretoria : [s.n.], 2007. http://upetd.up.ac.za/thesis/available/etd-05122008-100402/.

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29

Blanco, Carcache Peter Josephin. "Chemical Characterization and Biological Evaluation of Secondary Metabolites Isolated from Glycosmis ovoidea." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1580383951030389.

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30

Jeffery, Richard William Paul. "Ethoxyresorufin-O-deethylase (EROD) inducing potency of polycyclic aromatic hydrocarbons (PAHs) in avian hepatocyte cultures: Investigations of the ability of an in vitro bioassay to predict the toxic potency of PAHs." Thesis, University of Ottawa (Canada), 2001. http://hdl.handle.net/10393/9164.

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Eighteen polycyclic aromatic hydrocarbons (PAHs) and 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD) were examined for their potencies to induce ethoxyresorufin-O-deethylase (EROD) activity in primary cultures of White Leghorn chicken (Gallus domesticus), Pekin duck (Anas platyrhynchos), and Greater Scaup (Aythya marila) embryo hepatocytes. Of the 18 PAHs, only eight induced EROD activity. In chicken hepatocytes the rank order of potency of the eight EROD inducing PAHs was BkF ≥ DahA > Ind > BaA ≥ BghiP ≥ Chr ≥ BaP > BNT. A log-log plot of the ECthr plotted against the LD50 (LD50 data fr

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MORENO, CAROLINA dos S. "Avaliação dos efeitos da radiação ionizante e do Resveratrol na cultura de células tumorais de pulmão." reponame:Repositório Institucional do IPEN, 2016. http://repositorio.ipen.br:8080/xmlui/handle/123456789/26829.

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Submitted by Claudinei Pracidelli (cpracide@ipen.br) on 2016-11-11T17:21:57Z No. of bitstreams: 0<br>Made available in DSpace on 2016-11-11T17:21:57Z (GMT). No. of bitstreams: 0<br>O carcinoma mucoepidermóide de pulmão, um tipo histológico que deriva das glândulas mucosas traqueobrônquicas, manifesta-se com sintomas obstrutivos e tende a comprometer a traqueia. Com finalidade curativa ou paliativa da doença, atualmente há uma forte tendência na oncologia em desenvolver estratégias terapêuticas que visam à administração de compostos com elevado potencial de otimizar o efeito do tratamento com

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Leusch, F. D. L. "Estrogenic and androgenic potential of municipal sewage in Australia and New Zealand." Lincoln University, 2004. http://hdl.handle.net/10182/1983.

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Studies in Europe, Japan, and North America have reported that wild fish exposed to treated sewage effluents can exhibit significant physiological and reproductive abnormalities consistent with exposure to hormonally active chemicals. The main objective of this research project was to examine the estrogenic and androgenic activity in treated sewage to determine the risk associated with treated sewage discharges in Australia and New Zealand. Several bioassays, including a sheep estrogen receptor and a rainbow trout androgen receptor binding assay, were set up and validated with model compounds

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SNYDER, STEPHEN. "Modeling the Thermal Stability of in vitro Diagnostic Bioassays." Thesis, 2011. http://hdl.handle.net/1974/6303.

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The objective of this work is to develop mathematical models for predicting the thermal stability of commercial diagnostic assays. These assays are a product of the Point of Care division of Abbott laboratories, and are used for analyzing patient blood samples for specific substances. The accuracy of the results from these diagnostic tests relies on the activity of specific biological and/or chemical components of the sensors. Mathematical models that describe the stability of these active components are useful for supporting product shelf-life claims and for the design and implementation of a

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Howell, Janet Sue. "Evaluation of three in vitro bioassays for measuring the anthelmintic activity of plant extracts containing condensed tannins." 2009. http://purl.galileo.usg.edu/uga%5Fetd/howell%5Fjanet%5Fs%5F200905%5Fms.

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Youn, Hyun-Yi. "Ultraviolet B and blue light - induced phototoxic effects on retinal pigment epithelium using in vitro assays." Thesis, 2008. http://hdl.handle.net/10012/3973.

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It is well known that ultraviolet (UV) B (280-315 nm) and blue light (400-500 nm) radiation can produce phototoxic lesions in the neural retina and the retinal pigment epithelium (RPE). In the first section of this thesis, bovine lens cells (epithelium and superficial cortical fibre cell) and human retinal pigment epithelial (ARPE-19) cells were used to characterize in vitro changes following oxidative stress with UVB radiation in ocular lens optics and cellular function in terms of mitochondrial dynamics. In the second part, human retinal pigment epithelial (ARPE-19) cells and in vitro bioa

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Ngoma, Lubanza. "Characterization, host bioassay, and in vitro culture of indigenous entompathogenic nematodes and their bacterial symbionts." Thesis, 2009. http://hdl.handle.net/10539/6880.

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The prevailing use of chemical pesticides has generated several problems including insecticide resistance, outbreak of secondary pests, safety risks for humans and domestic animals, contamination of ground water and decrease in biodiversity among other environmental concerns (Webster, 1982). These problems and the nonsustainability of control programs based mainly on conventional insecticides have stimulated increased interest in the development and implementation of costeffective, environmentally safe alternatives to chemical pesticides for insect pest control. One of the most promisin

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Laqua, Anja. "Reaktive Toxizität in vitro: Bioassay-Analyse organischer Elektrophile und Proelektrophile mit den Ciliaten Tetrahymena pyriformis." Doctoral thesis, 2013. https://tubaf.qucosa.de/id/qucosa%3A22903.

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Es wird eine Bioassay-Analyse von 168 Testsubstanzen gegenüber Tetrahymena pyriformis beschrieben. Mithilfe dieses In-vitro-Ansatzes konnte eine erste prognostische Aussage über die toxische Wirkung unbekannter Stoffe getroffen werden. Aus den Konzentrations-Wirkungs-Beziehungen erfolgte eine Bestimmung der Toxizitätserhöhung gegenüber der Narkoselevel-Toxizität. Dadurch war eine mechanistische Interpretation der Wirkstärke der Fremdstoffe möglich. Die Wirkung der Fremdstoffe basiert auf direkten toxikologisch relevanten Reaktionsmechanismen mit nukleophilen Biomolekülen oder nach entsprechend

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Zhang, Weicheng. "Prediction of the skin sensitization potential of organic chemicals through in vitro bioassay and chemoassay information." Doctoral thesis, 2014. https://tubaf.qucosa.de/id/qucosa%3A22971.

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Skin sensitization resulting for allergic contact dermatitis (ACD) is an occupational and environmental health issue. The allergic hazard for workers and consumers is a serious problem for individuals, employers and marketing certain products. Consequently, it is necessary to accurately identify chemicals skin sensitization potential. According to the new EU chemical regulation REACH (Registration, Evaluation, Authorization and Restriction of Chemicals), information of skin sensitization of chemicals manufactured or imported at or above 1 ton/year should be available. Currently, valid approach

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PAULIČ, Radim. "Hodnocení účinnosti entomopatogenní houby Beauveria bassiana pomocí standardního laboratorního biotestu." Master's thesis, 2011. http://www.nusl.cz/ntk/nusl-55068.

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In laboratory bioassays, the efficacy of the entomopathogenic fungus Beauveria bassiana against the yellow mealworm (Tenebrio molitor) was tested under various temperature conditions. Six different strains of fungus B. bassiana was investigated. The evaluation was based on vitality bioassays including germination and growth index assessment and the bioassay of virulence based on target organism T. molitor was also assessed growth and yield of conidia different strains of fungus B. bassiana on natural substrates and artificial nutrient substrates.

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Hong, Julie Ann. "Characterization of a cypia gene expression in rainbow trout implications for the development of an in vitro bioassay for determination of TCDD toxicity /." 1999. http://catalog.hathitrust.org/api/volumes/oclc/42025280.html.

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Thesis (M.S.)--University of Wisconsin--Madison, 1999.<br>Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 52-60).

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"Bioassay-guided isolation, characterization, and mechanistic study of the bioactive components from scutellaria barbata for the anti-proliferative effect on human hepatoma cells in vitro adn in vivo." Thesis, 2007. http://library.cuhk.edu.hk/record=b6074509.

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Both mRNA and protein expression levels of P-glycoprotein, one of the major factors involved in drug resistance, was decreased in Pa-treated R-HepG2 cells. The chemo-sensitivity of these MDR cells towards doxorubicin would be enhanced by pretreatment of Pa.<br>In the study, 35 TCMs with historical background in treating liver diseases were screened. S. barbata was chosen for intensive studies based on its significant anti-hepatoma activity. Using bioassay-guided purification approach, an active component, pheophorbide a (Pa) - a chlorophyll derivative, was isolated from Scutellaria barbata.<br

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"In vitro and in vivo mechanistic studies of the wound-healing effects of Astragali Radix and phytochemical analysis of its active fractions/components isolated using bioassay-guided fractionation." 2013. http://library.cuhk.edu.hk/record=b5884429.

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Lai, Kwok Kin.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2013.<br>Includes bibliographical references (leaves 229-251).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstract also in Chinese.

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Silva, Isabel Gomes da. "Estabelecimento de uma metodologia de cultura in vitro visando a limpeza de infecções virais de material clonal de populações de Allium sativum L." Master's thesis, 2013. http://hdl.handle.net/1822/27819.

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Dissertação de mestrado em Biologia Molecular, Biotecnologia e Bioempreendedorismo em Plantas<br>O género Allium encontra-se distribuído por todo o mundo e é de grande importância económica. O alho (Allium sativum L.) é a segunda espécie mais importante deste género tanto pelo seu uso na dieta humana, como pelas suas propriedades terapêuticas. Um dos principais problemas que afectam a produtividades desta cultura e a qualidade do bolbo são as doenças virais sistémicas. Associações de vírus pertencentes aos géneros Potyvirus – Onion yellow dwarf virus e Leek yellow stripe virus - e Carlavi

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