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Relevant bibliographies by topics / Bioavailability of W. Somnifera

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Academic literature on the topic 'Bioavailability of W. Somnifera'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Bioavailability of W. Somnifera"

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Devaraj Reddy KN, Srilakshmi Aluri, Prathvi Shetty, et al. "Assessing the Efficacy and Biological Benefits of Withanolide-rich Withania somnifera Root Extract." Annual Research & Review in Biology 39, no. 5 (2024): 54–64. http://dx.doi.org/10.9734/arrb/2024/v39i52081.

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The medicinal plant Withania somnifera, usually referred to as Ashwagandha, is a member of the Solanaceae family. The presence of Withanolides in the roots is responsible for a number of pharmacological effects in Ashwagandha. Withanolides have been demonstrated to be an effective neuronal, immune, anti-stress, and anti-cancer agent. However, Withanolides demonstrated limited permeability, lowering the bioavailability and efficacy of active compounds. The goal of the study was to ascertain the biological efficacy of Ashwagandha Composition, a blend of W. somnifera milk extract and water extrac

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Li, Mingxuan, Lin Liu, Sen Lin Zhu, and Cheng Zhang. "Somniferine Emerging As Lead Phytochemical From Withania somnifera to Target CASP3, JUN, and PTGS2 in Lung Cancer." Acta Poloniae Pharmaceutica - Drug Research 81, no. 5 (2025): 813–30. https://doi.org/10.32383/appdr/196239.

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This integrated research uses computational approaches to examine the lung cancer targeting potential of Withania somnifera root bioactive principles. IMPPAT and SwissADME were used to screen phytochemicals for druglikeness and bioavailability. MOLSOFT measured druglikeness, whereas ProTox 3.0 assessed toxicity. SwissTarget Prediction and GeneCards identified biological and lung cancer targets, respectively. Venn plots showed overlapping targets. Cytoscape used Cytohubba-plugin to display string database PPI and identify hub-genes. ShinyGo analysed BP, CC, MF, and KEGG pathways for enriched hu

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Nykvist, Cathryn Dawn, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "A Comprehensive Physical, Spectroscopic, and Thermal Characterization of Withania somnifera (Ashwagandha) Root Extract Treated with the Energy of Consciousness (The Trivedi Effect®)." International Journal of Biomedical Materials Research 5, no. 1 (2017): 5–14. https://doi.org/10.5281/zenodo.822549.

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Withania somnifera (Ashwagandha) root extract possesses a broad range of pharmacological activities. The aim of current study was to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts. One part was denoted as the control, while the other part was defined as The Trivedi Effect® - Biofield Energy Treated sample, which received

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Vincent, Dianne Heather, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "A Comprehensive Physical, Spectroscopic, and Thermal Characterization of Withania somnifera (Ashwagandha) Root Extract Treated with the Energy of Consciousness (The Trivedi Effect®)." International Journal of Biomedical Materials Research 5, no. 1 (2017): 5–14. https://doi.org/10.5281/zenodo.834415.

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Withania somnifera (Ashwagandha) root extract possesses a broad range of pharmacological activities. The aim of current study was to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts. One part was denoted as the control, while the other part was defined as The Trivedi Effect® - Biofield Energy Treated sample, which received

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Konersman, Douglas Jay, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "A Comprehensive Physical, Spectroscopic, and Thermal Characterization of Withania somnifera (Ashwagandha) Root Extract Treated with the Energy of Consciousness (The Trivedi Effect®)." International Journal of Biomedical Materials Research 5, no. 1 (2017): 5–14. https://doi.org/10.5281/zenodo.835640.

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Abstract:

Withania somnifera (Ashwagandha) root extract possesses a broad range of pharmacological activities. The aim of current study was to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts. One part was denoted as the control, while the other part was defined as The Trivedi Effect® - Biofield Energy Treated sample, which received

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Feeney, Elizabeth Ann, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "A Comprehensive Physical, Spectroscopic, and Thermal Characterization of Withania somnifera (Ashwagandha) Root Extract Treated with the Energy of Consciousness (The Trivedi Effect®)." International Journal of Biomedical Materials Research 5, no. 1 (2017): 5–14. https://doi.org/10.5281/zenodo.836593.

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Abstract:

Withania somnifera (Ashwagandha) root extract possesses a broad range of pharmacological activities. The aim of current study was to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts. One part was denoted as the control, while the other part was defined as The Trivedi Effect® - Biofield Energy Treated sample, which received

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Prague, Jay Anthony, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "A Comprehensive Physical, Spectroscopic, and Thermal Characterization of Withania somnifera (Ashwagandha) Root Extract Treated with the Energy of Consciousness (The Trivedi Effect®)." International Journal of Biomedical Materials Research 5, no. 1 (2017): 5–14. https://doi.org/10.5281/zenodo.838384.

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Abstract:

Withania somnifera (Ashwagandha) root extract possesses a broad range of pharmacological activities. The aim of current study was to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts. One part was denoted as the control, while the other part was defined as The Trivedi Effect® - Biofield Energy Treated sample, which received

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Starodub, Joanne Lydia, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "A Comprehensive Physical, Spectroscopic, and Thermal Characterization of Withania somnifera (Ashwagandha) Root Extract Treated with the Energy of Consciousness (The Trivedi Effect®)." International Journal of Biomedical Materials Research 5, no. 1 (2017): 5–14. https://doi.org/10.5281/zenodo.839093.

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Abstract:

Withania somnifera (Ashwagandha) root extract possesses a broad range of pharmacological activities. The aim of current study was to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts. One part was denoted as the control, while the other part was defined as The Trivedi Effect® - Biofield Energy Treated sample, which received

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Rasdan, Karan, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "A Comprehensive Physical, Spectroscopic, and Thermal Characterization of Withania somnifera (Ashwagandha) Root Extract Treated with the Energy of Consciousness (The Trivedi Effect®)." International Journal of Biomedical Materials Research 5, no. 1 (2017): 5–14. https://doi.org/10.5281/zenodo.840618.

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Abstract:

Withania somnifera (Ashwagandha) root extract possesses a broad range of pharmacological activities. The aim of current study was to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts. One part was denoted as the control, while the other part was defined as The Trivedi Effect® - Biofield Energy Treated sample, which received

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Mayne, Maire Anne, Mahendra Kumar Trivedi, Gopal Nayak, Alice Branton, and Dahryn Trivedi. "A Comprehensive Physical, Spectroscopic, and Thermal Characterization of Withania somnifera (Ashwagandha) Root Extract Treated with the Energy of Consciousness (The Trivedi Effect®)." International Journal of Biomedical Materials Research 5, no. 1 (2017): 5–14. https://doi.org/10.5281/zenodo.843623.

Full text

Abstract:

Withania somnifera (Ashwagandha) root extract possesses a broad range of pharmacological activities. The aim of current study was to explore the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on the physical, spectroscopic, and thermal properties of ashwagandha root extract using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Ashwagandha root extract was divided into two parts. One part was denoted as the control, while the other part was defined as The Trivedi Effect® - Biofield Energy Treated sample, which received

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Dissertations / Theses on the topic "Bioavailability of W. Somnifera"

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Garcia-Fernandez, Jenifer [Verfasser], Michael W. [Gutachter] Linscheid, Maria [Gutachter] Montes-Bayón, and Ulrich [Gutachter] Panne. "Bioavailability studies of Iron Nanoparticles in Biological Samples using Mass Spectrometric Techniques / Jenifer Garcia-Fernandez ; Gutachter: Michael W. Linscheid, Maria Montes-Bayón, Ulrich Panne." Berlin : Humboldt-Universität zu Berlin, 2018. http://d-nb.info/1185174885/34.

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Books on the topic "Bioavailability of W. Somnifera"

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Brzozowska, Anna. Biodostępność żelaza, cynku i miedzi w zależności od ilości i wzajemnych proporcji tych pierwiastków w diecie. Wydawn. SGGW, 1991.

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Book chapters on the topic "Bioavailability of W. Somnifera"

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Kumar, Brijesh, Vikas Bajpai, Vikaskumar Gond, Surabhi Tiwari, and K. P. Madhusudanan. "Quantitative Determination of Six Withanolides in Five Varieties of W. Somnifera Grown under Different Soil Treatment Conditions." In Phytochemistry of Withania somnifera. CRC Press, 2021. http://dx.doi.org/10.1201/9781003186274-2.

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Rajasreelatha, V., M. Thippeswamy, M. Siva Kumar, V. Naga Padmavathi, and T. Pullaiah. "A Review of Tissue Culture Studies on Withania somnifera (L.) Dunal - An Important Medicinal Plant." In Micropropagation of Medicinal Plants. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815196146124010005.

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Withania somnifera, commonly known as 'Indian ginseng', is a highly important and valuable medicinal plant in traditional family medicine, containing a variety of medicinal bioactive molecules for over 3,000 years. Various medicinal properties of plants are attributed to steroidal lactones (withanolides) present in plants. Its commercial cultivation is hampered by low seed viability and germination rates. Tissue culture techniques can play an important role in the preservation, clonal propagation, and qualitative improvement of this medicinal plant. In vitro shoot differentiation and microprop

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Kumar Sinha, Ambarish, Hagera Dilnashin, Hareram Birla, and Gaurav Kumar. "Role of Withania somnifera (Ashwagandha) in Neuronal Health." In Indopathy for Neuroprotection: Recent Advances. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815050868122010016.

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Neurodegenerative disease refers to the progressive deterioration of neurologic function which leads to loss of speech, vision, hearing, and movement. It is also associated with seizures, eating difficulties, and memory impairment. Natural products have emerged as potential neuroprotective agents for the treatment of neurodegenerative diseases due to the enormous adverse effects associated with pharmacological drugs. Withania somnifera (Ashwagandha) is a traditional Ayurvedic medicine, used in India as a general tonic. It contains withanolides, and phytochemicals that may have adaptogenic prop

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Kulavi, Sohini, Debajit Dhar, Karan Iyer, Arnab Kumar Ghosh, and Jaya Bandyopadhyay. "Unveiling the Potentials of Withania somnifera (L.) Dunal as a Precise Therapeutic Intervention Against Glioblastoma Multiforme." In Life as Basic Science: An Overview and Prospects for the Future [Volume: 1]. International Academic Publishing House (IAPH), 2024. http://dx.doi.org/10.52756/lbsopf.2024.e01.007.

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Glioblastoma multiforme (GBM) is the most severe and fatal form of brain tumor, leading to a poor survival rate in patients and making a significant contribution to cancer-related deaths. The typical approaches to treating GBM involve surgical procedures followed by chemotherapy, targeting molecular pathways involving receptors like Epidermal Growth Factor Receptor (EGFR, EGFRvIII) and Vascular Endothelial Growth Factor Receptor (VEGFR) to modulate various cell signaling pathways. However, the effectiveness of current GBM treatments is notably constrained. Withania somnifera (WS) (L.) Dunal, c

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Takeda, S., H. Obata, A. Okubo, M. Sato, and Y. Kondo. "Bioavailability and Biogeochemical Processes of Trace Metals in the Surface Ocean." In Western Pacific Air-Sea Interaction Study. TERRAPUB, 2014. http://dx.doi.org/10.5047/w-pass.a03.001.

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T. Galatage, Sunil, Rahul Trivedi, Durgacharan A. Bhagwat, et al. "Self-nano Emulsifying Formulations: An Encouraging Approach for Bioavailability Enhancement and Future Perspective." In Dosage Forms [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108703.

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Currently lipid-based formulations are playing a vital and promising role in improving the oral bioavailability of poorly water-soluble drugs. Lipid based formulations mainly consist of a drug dissolved in lipids such as triglycerides, glycerides, oils and surface active agent. Self nanoemulsifying formulations (SNEF) are isotropic mixtures of lipids/oils, surfactants and co-surfactants. On mild agitation followed by dilution in aqueous media, such as GI fluids, SNEF can form fine oil-in-water (o/w) nanoemulsions. Present chapter summarizes different types of lipid formulations with special em

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Kesavan, Karthikeyan, Parasuraman Mohan, Sunil K. Jain, Olivia Parra-Marín, and Selvasankar Murugesan. "Nanoemulsion: A Potential Carrier for Topical Drug Delivery." In Nanoparticles and Nanocarriers-Based Pharmaceutical Formulations. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815049787122010011.

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Nanoemulsions (NEs) are stable nanocarrier systems consisting mainly of oil and water, which are stabilized by surfactant with cosurfactant. Due to their typical size, nano-emulsions are transparent or translucent, and minute droplet size makes them stable against sedimentation or creaming. The nanoemulsion system may be in the form of oil-in-water (O/W) or water-in-oil (W/O). The recent literature revealed that NEs as a colloidal carrier system has been confirmed to be a valuable strategy to improve the bioavailability of topically applied drugs. NE has been proposed as a viable alternative t

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Conference papers on the topic "Bioavailability of W. Somnifera"

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Emanuele, R. M., and J. Fareed. "THE EFFECT OF MOLECULAR WEIGHT ON THE RELATIVE BIOAVAILABILITY OF HEPARIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644179.

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Three fractions of different molecular weight (M. W.) were obtained from gel-filtration of porcine mucosal heparin. These fractions along with unfractionated and a low M. W. heparin (CY 216) were compared for relative bioavailability in primates (Macaca mulatta: n = 5). The M. W.'s of all fractions were determined using high performance liquid chromatography - gel permeation and characterizied in terms of mean M. W., peak M. W. and M. W. distribution. Area under the plasma concentration time curve (AUC) was calculated by the trapezoidal method after intravenous and subcutaneous administration

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Neves, Marcos A., Isao Kobayashi, and Mitsutoshi Nakajima. "Scaling-Up Microchannel Emulsification Foreseeing Novel Bioactives Delivery Systems." In ASME 2013 11th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icnmm2013-73116.

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In the recent years, emulsification technologies that generate droplets individually have attracted a great deal attention in various fields, e.g., for chemicals, cosmetics, foods, and pharmaceuticals. Such drop-by-drop emulsification technologies include membrane emulsification using microporous membranes and microchannel (MC) emulsification, among others. The authors developed MC emulsification chips, consisting of parallel microgrooves or compactly arranged straight through-holes. Using this MC emulsification technique, the authors have evaluated the formulation a two-phase system consistin

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Reports on the topic "Bioavailability of W. Somnifera"

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Singh, Vineet, and Deepak Mundkinajeddu. Adulteration of Ashwagandha (Withania somnifera) Roots and Extracts. ABC-AHP-NCNPR Botanical Adulterants Prevention Program, 2019. https://doi.org/10.59520/bapp.bapb/gsha8763.

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The goal of this bulletin is to provide information and/or updates on the issue of adulteration of ashwagandha (Withania somnifera, Solanaceae) root materials and their extracts to the international herbal products industry and extended natural products community in general. It is intended to complement the previously published work on W. somnifera root and extract adulteration, i.e., the American Herbal Pharmacopoeia monograph by Upton et al.1 and the article by Mundkinajeddu et al.2 by reporting new data on the occurrence of adulteration, the market situation, and its subsequent consequences

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Tengamnuay, Parkpoom. Efficacy and mechanistic studies of chitosan as nasal absorption enhancer of peptide drugs : research report. Chulalongkorn University, 1999. https://doi.org/10.58837/chula.res.1999.27.

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Objective. To evaluation the in vivo efficacy of chitosan as nasal absorption enhancers of peptides in rats and compare the results with that of hydroxypropyl- and dimethyl-Beta-cyclodextrins (HPBetaCD and DMBetaCD). Methods. Two types of chitosan. i.e., the free base (CSJ) and the glutamate salt form (CSG) were evaluated for their nasal absorption enhancing effect on salmon calcitonin (sCT) using an in vibo rat absorption technique. Solutions containing sCT and chitosan (0 to 1.25 % w/v) in isotonic phosphate buffers (pH 3.0 to 6.0) were nasally administered at the dose of 10 IU/kg. The plasm

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