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Journal articles on the topic 'Biochemical research methods'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Edelev, N. S., V. G. Vorob'ev, and I. S. Edelev. "Application of biochemical research methods for solving questions of forensic medical practice." Sudebno-meditsinskaya ekspertiza 62, no. 4 (2019): 63. http://dx.doi.org/10.17116/sudmed20196204163.

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2

Gureeva, N. V. "River water quality research within the city limits using some biochemical methods." Contemporary Problems of Ecology 4, no. 1 (2011): 84–90. http://dx.doi.org/10.1134/s1995425511010140.

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3

K, Hema Shree. "Saliva Collection Methods: A Comprehensive Guide for Scientific Research." International Journal of Orofacial Biology 7, no. 2 (2023): 21–25. http://dx.doi.org/10.56501/intjorofacbiol.v7i2.1058.

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Saliva has recently emerged as a valuable biological fluid in scientific research due to its rich biochemical composition and non-invasive accessibility. This article aims to provide a comprehensive guide to saliva collection methods in scientific research, covering procedures, materials, contamination prevention, storage protocols, collection methods, clinical trial considerations, and sample stabilization. By adhering to meticulous protocols, researchers can ensure the accuracy and reliability of their findings, thus maximizing the potential of saliva as a biospecimen for various research ap

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Aguilar, Adriana, Jacques Planas, Enrique Trilla, and Juan Morote. "Methods for Evaluating the Efficacy of Medical Castration: A Systematic Review." Cancers 15, no. 13 (2023): 3479. http://dx.doi.org/10.3390/cancers15133479.

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Measuring serum testosterone determination during medical castration is recommended by prostate cancer (PCa) guidelines to assess its efficacy and define castration resistance. It has been suggested that other biochemical compounds, such as free testosterone or luteinising hormone (LH), could also assess castration efficacy. We aimed to analyse the current evidence for serum biochemical compounds that could be appropriate candidates for evaluating medical castration efficacy. A systematic review was conducted after two investigators independently searched the literature in the PubMed, Cochrane

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Murskiy, S. I. "On possibility of using routine biochemical techniques for research of alternative biological human liquids." Medical alphabet 4, no. 35 (2020): 54–57. http://dx.doi.org/10.33667/2078-5631-2019-4-35(410)-54-57.

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Biochemical studies of alternative human biological fluids are not common in laboratory practice due to the lack of validation methods. The aim of the study was to validatе on semen plasma routine biochemical research methods using an automatic biochemical analyzer. The studies were carried out on a Cobas Integra 400 plus automatic biochemical analyzer (Roche, Switzerland) using original Roche reagents (Switzerland). Materials for the study were 30 samples of semen plasma obtained from clinically healthy men of reproductive age. Planning and organization of validation activities were carried o

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Lane, Dan. "Expect the unexpected: presenting research leads to unforeseen gains." Biochemist 41, no. 4 (2019): 48–49. http://dx.doi.org/10.1042/bio04104048.

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Dan Lane is a first year PhD student at the University of Leicester, developing biochemical methods in non-adherence testing alongside Leicester Diabetes Centre. A pilot study he helped to conduct prior to the start of his postgraduate degree was accepted by Diabetes UK and so, with the help of a travel grant from the Biochemical Society, he travelled to Liverpool to present his work. The Biochemical Society provides General Travel Grants to support attendance at scientific meetings, training events or any other event relevant to your career. Postgraduate, Early Career, Full and Emeritus Membe

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Feng, Hao. "Research Progress in Pharmaceutical Wastewater Treatment Technology." E3S Web of Conferences 118 (2019): 04019. http://dx.doi.org/10.1051/e3sconf/201911804019.

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With the development of the medical industry, according to the characteristics of pharmaceutical wastewater, the corresponding pharmaceutical wastewater treatment technology is used to optimize the technology in the production process, which is a measure for the welfare of human health. The wastewater discharged during the production process, especially the pharmaceutical wastewater, is very polluting to the human environment. According to the physicochemical and biochemical and combined process technologies used in pharmaceutical wastewater at home and abroad, new methods are used to improve

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Vranová, Valerie, Theodore Danso Marfo, and Klement Rejšek. "Soil Scientific Research Methods Used in Archaeology – Promising Soil Biochemistry: a Mini-review." Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis 63, no. 4 (2015): 1417–26. http://dx.doi.org/10.11118/actaun201563041417.

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This work seeks to review soil scientific methods that have been used and are still being used in archaeology. This review paper aims at emphasising the importance of soil science practice to archaeology thus adding a scientific analytical nature to the cultural nature of archaeology. Common methods (physical, chemical and biochemical) used to analyse archaeological soils and artefacts is touched on and their strengths and shortcomings duly noted to become the base for future research. Furthermore, the authors made emphasis on distinctive excavating/sampling methods, biochemical analyses focus

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Zhu, Ziyue. "Current common prodrug delivery methods and biochemical property." Theoretical and Natural Science 32, no. 1 (2024): 67–71. http://dx.doi.org/10.54254/2753-8818/32/20240798.

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Prodrugs are pivotal in overcoming drug delivery and absorption challenges. These bioreversible derivatives are strategically designed to address medicines poor bioavailability and administration constraints. Prodrugs offer versatile solutions for various delivery methods, including oral, dermal, nasal, and central nervous system (CNS) routes and tumor targeting. This literature review aims to summarize several prodrugs delivery methods. The report also focuses on the common concepts of prodrug design. The utilization of prodrugs also includes innovative strategies, such as receptor-mediated i

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Maharani, Ni Putu Radela, Nur Ashfiya Fadlyah, Dyah Ayu Woro Setyaningrum, and Nany Hairunisa. "Effects of Euthanasia on Animal Research." Veterinary Biomedical and Clinical Journal 6, no. 1 (2024): 41–46. http://dx.doi.org/10.21776/ub.vetbioclinj.2024.006.01.6.

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The use of experimental animals is widely conducted in the medical field, both for research on the processes of disease occurrence (pathogenesis), the causes of disease (etiology), and research on therapy. Therefore, it is important to understand how euthanasia in experimental animals affects the integrity of the sample and its influence on research results. This article was compiled from several literature sources searched from Google Schoolar and PubMed published within the last 10 years, with keywords such as "code of ethics in experimental animals", "methods of euthanasia in experimental a

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Goncharov, N. P., G. V. Katsiia, and N. M. Malysheva. "Modern biochemical methods for the diagnostics of pheochromocytoma." Problems of Endocrinology 58, no. 2 (2012): 10–15. http://dx.doi.org/10.14341/probl201258210-15.

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The objective of the present work was to estimate the possibility of using the ELISA technique for the quantitative analysis of the metanephrine and normetanephrine levels in urine and to determine the cross-off points for the discrimination between their normal and pathological values for the purpose of diagnostics of pheochromocytoma. Methylated derivatives of adrenaline and noradrenaline were measured in 3,234 urine sample obtained from the patients presenting with elevated arterial pressure, resistance to therapy, and adrenal mass lesions who had visited the inpatient and outpatient depart

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Gasparini, Giampietro, Franco Pozza, Ruggero Dittadi, Salvatore Meli, Stefania Cazzavillan, and Pierantonio Bevilacqua. "Progesterone receptor determined by immunocytochemical and biochemical methods in human breast cancer." Journal of Cancer Research and Clinical Oncology 118, no. 7 (1992): 557–63. http://dx.doi.org/10.1007/bf01225273.

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13

Zhang, Yali, Junqi Xiao, Kangting Yan, et al. "Advances and Developments in Monitoring and Inversion of the Biochemical Information of Crop Nutrients Based on Hyperspectral Technology." Agronomy 13, no. 8 (2023): 2163. http://dx.doi.org/10.3390/agronomy13082163.

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Crop nutrient biochemical information (mainly including chlorophyll class and nutrient elements mainly nitrogen, phosphorus and potassium) is an important basis for revealing crop growth and development patterns and their relationship with the environment. Hyperspectral technology has been rapidly developed and applied in crop nutrient biochemical information monitoring research. This paper firstly describes the theoretical basis of hyperspectral technology for monitoring crop nutrients and biochemical information. Then, the research progress of hyperspectral technology in monitoring nutrient

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Niyonambaza, Shimwe Dominique, Praveen Kumar, Paul Xing, et al. "A Review of Neurotransmitters Sensing Methods for Neuro-Engineering Research." Applied Sciences 9, no. 21 (2019): 4719. http://dx.doi.org/10.3390/app9214719.

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Neurotransmitters as electrochemical signaling molecules are essential for proper brain function and their dysfunction is involved in several mental disorders. Therefore, the accurate detection and monitoring of these substances are crucial in brain studies. Neurotransmitters are present in the nervous system at very low concentrations, and they mixed with many other biochemical molecules and minerals, thus making their selective detection and measurement difficult. Although numerous techniques to do so have been proposed in the literature, neurotransmitter monitoring in the brain is still a c

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Williams, Robin S. B. "Employing multiple models, methods and mechanisms in bipolar disorder research." Biochemical Society Transactions 37, no. 5 (2009): 1077–79. http://dx.doi.org/10.1042/bst0371077.

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BD (bipolar disorder) is a devastating condition, giving rise to debilitating mood swings and a greatly increased likelihood of suicide. Research into the origins, progression and treatment of BD has been slow, primarily due to lack of suitable model systems for BD research. However, the complexity of the neurological basis for mood, variability in patient populations and the lack of clear readouts for BD diagnosis also provide significant problems for research in this area. In this Biochemical Society Focused Meeting, held at Royal Holloway University of London, approx. 40 national and intern

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Lages, Paulo Sergio, Luciano Prado Junior, Leonardo Prado, and Luciana Lages. "Experience of a single Brazilian center on PSMA-PET in biochemical recurrence in patients with prostate cancer." Journal of Clinical Oncology 37, no. 7_suppl (2019): 134. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.134.

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134 Background: Biochemical recurrence in prostate cancer is a common event, and we have data showing that PSMA-PET may guide therapy when it happens. Objectives: Verify the sensibility of PSMA-PET on biochemically recurrent prostate cancer and correlate it with PSA level and Gleason score. Methods: From October 2015 to August 2018, 547 PSMA-PET (68Ga-PSMA) was performed to evaluate prostate cancer individuals. 276 patients had already been treated from prostate cancer and were in biochemical recurrence. From these patients, 122 had information regarding Gleason Score. Results: From the 276 pa

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17

Alexeev, Yuri, Michael P. Mazanetz, Osamu Ichihara, and Dmitri G. Fedorov. "GAMESS As a Free Quantum-Mechanical Platform for Drug Research." Current Topics in Medicinal Chemistry 12, no. 18 (2013): 2013–33. http://dx.doi.org/10.2174/1568026611212180008.

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Driven by a steady improvement of computational hardware and significant progress in ab initio method development, quantum-mechanical approaches can now be applied to large biochemical systems and drug design. We review the methods implemented in GAMESS, which are suitable to calculate large biochemical systems. An emphasis is put on the fragment molecular orbital method (FMO) and quantum mechanics interfaced with molecular mechanics (QM/MM). The use of FMO in the protein-ligand binding, structure-activity relationship (SAR) studies, fragment- and structure-based drug design (FBDD/SBDD) is dis

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18

Makarkina, M. A., and E. N. Sedov. "Apple tree selection methods for fruit biochemical composition improving." Вестник российской сельскохозяйственной науки, no. 1 (February 15, 2023): 48–52. http://dx.doi.org/10.31857/2500-2082/2023/1/48-52.

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Apple is the most widespread crop in the world, the fruits of which contain nutrients (sugars) and biologically active substances (ascorbic acid and phenolic compounds) that have a beneficial effect on the human body. One of the priorities in the creation of new apple cultivars is to improve the chemical composition of fruits. Such work is carried out in the Russian Research Institute of Fruit Crop Breeding (VNIISPK). The method of repeated and geographically distant crosses is used. Over the years of breeding work at the Institute, a number of cultivars have been created that surpass previous

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19

Molino, A., R. Micciolo, M. Turazza, et al. "Estrogen receptors in 699 primary breast cancers: A comparison of immunohistochemical and biochemical methods." Breast Cancer Research and Treatment 34, no. 3 (1995): 221–28. http://dx.doi.org/10.1007/bf00689713.

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20

Haemmerli, G., W. Müller-Glauser, P. Bruckner, I. Hauser-Urfer, and P. Sträuli. "Tumor-associated desmoplasia in the rabbit mesentery characterized by morphological, biochemical and cytophotometric methods." International Journal of Cancer 35, no. 4 (1985): 527–34. http://dx.doi.org/10.1002/ijc.2910350417.

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21

Chen, Bingjie, Hui He, Xiao Wang, et al. "Research Progress on Shrimp Allergens and Allergenicity Reduction Methods." Foods 14, no. 5 (2025): 895. https://doi.org/10.3390/foods14050895.

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Shrimp are highly favored by consumers for their delicious taste and rich nutritional value. However, reports of allergic reactions caused by shrimp and its derivatives have been increasing, significantly impacting consumer health and posing a growing global food safety concern. This article introduces the structure and biochemical characteristics of major allergenic proteins in shrimp, including tropomyosin (TM), arginine kinase, sarcoplasmic calcium-binding protein, myosin light chain, troponin C, and hemocyanin. Currently, there is no effective treatment for shrimp allergies, and prevention

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22

Hasanov, Elnur Latif oglu. "SIGNIFICANCE OF MULTIDISCIPLINARY RESEARCH OF HANDICRAFT PATTERNS OF GANJA ON THE BASIS OF BIOCHEMICAL METHODS." Theoretical & Applied Science 19, no. 11 (2014): 41–43. http://dx.doi.org/10.15863/tas.2014.11.19.8.

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23

Sengirbekova, L. K., and L. S. Syzdykova. "Research of safe methods of production of canned vegetables using grain crops." Journal of Almaty Technological University, no. 1 (April 10, 2022): 65–71. http://dx.doi.org/10.48184/2304-568x-2022-1-65-71.

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This article presents microbiological study of canned vegetable snacks replaced with various cereals.Currently both abroad and in our country, regulatory documents and recommendations on ensuring quality and safety of foodsare actively developed. The quality reduction and food spoilage may be related to biochemical (fermentative) processes inherent to products themselves. As another important factor, influencing on this can be microbiological contaminants.Miroorganisms constantly contaminates on surface of technological equipments, vegetables raw material and as a result they end up in canned

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Filer, Jameson, Huihuang H. Ding, and Sheng Chang. "Biochemical Methane Potential (BMP) Assay Method for Anaerobic Digestion Research." Water 11, no. 5 (2019): 921. http://dx.doi.org/10.3390/w11050921.

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Biochemical methane potential (BMP) tests are widely used for characterizing a substrate’s influence on the anaerobic digestion process. As of 2018, there continues to be a lack of standardization of units and techniques, which impacts the comparability and validity of BMP results. However, BMP methods continue to evolve, and key aspects are studied to further eliminate systematic errors. This paper aims to update these key aspects with the latest research progress both to introduce the importance of each variable to those new to BMP measurements and to show the complexity required to design a

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25

Garashova, M. A., and E. M. Alieva. "Diagnostic significance of hormonal, biochemical and echographic methods of research in postmenopausal women with endometrial cancer." Tumors of female reproductive system 15, no. 2 (2019): 62–66. http://dx.doi.org/10.17650/1994-4098-2019-15-2-62-66.

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Objective: to determine the significance of hormonal, biochemical, echographic research methods in the diagnosis of endometrial cancer.Materials and methods. Fifty patients with endometrial cancer with varying degree of severity were examined. The average age of patients with endometrial cancer was 62.4 ± 1.0 years. The study of the prevalence of the tumor process made it possible to establish that the frequency of patients with stage I was 68 %, with stage II – 30 %, and with stage III – 2 %.Results and conclusions. According to hormonal studies, the statistical significance of a decrease in

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Bachynskyi, Viktor, Oleh Vanchulyak, Marta Garazdiuk, Oleksandr Garazdiuk, and Oleh Palyvoda. "CSF RELEVANCE OF RESEARCH IN FORENSIC PRACTICE." Forensic-medical examination, no. 2 (November 20, 2015): 28–34. http://dx.doi.org/10.24061/2707-8728.2.2015.4.

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In a review article current data of cerebrospinal fluid investigation methods are present. It is described their ability to solve urgent issues of forensic practice, namely the postmortem interval, time of the injuries appearence and diagnosis of pathological states and processes that preceded or caused the death. In particular, the possibility of biochemical analytical methods of changes diagnosis of CSF compared with changes in biochemical parameters in the human blood both before and after death. Indicators studied spectrophotometric investigation of cerebrospinal fluid obtained by the auth

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Sigacheva, Т. В., I. I. Chesnokova, О. L. Gostyukhina, et al. "Assessment of recreational potential of Sevastopol bays using bioindication methods." South of Russia: ecology, development 16, no. 1 (2021): 151–67. http://dx.doi.org/10.18470/1992-1098-2021-1-151-167.

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Aim. Study of a group of biochemical parameters of the hepatopancreas and gills of the Black Sea mussel Mytilus galloprovincialis Lam. and the functional indicator of cardiac system adaptivity of mussels from Sevastopol bays with different levels of recreational and anthropogenic impact.Methods. Mussels were collected from four Sevastopol water areas (Kruglaya Bay, Kazachya Bay, Matyushenko Bay and Cape Khrustalnii) in autumn 2018. The bioindication methods used were based on application of functional (cardiac system adaptability) and biochemical indicators (antioxidant enzymes activity [AEA],

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Maryam, javaid Kainat Javeed. "Natural Product Research for Drug Development: Methods, Limitations, and Potential Applications." International Journal in Pharmaceutical Sciences 1, no. 11 (2023): 356–64. https://doi.org/10.5281/zenodo.10149044.

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The multifaceted strategy used in contemporary exploration on the development of new medicines from medicinal shops combines botanical, phytochemical, biochemical combinatorial chemistry, and bioassay- guided separation ways. Natural coffers continue to offer an volition to pharmacological leads in the fight against multitudinous deadly conditions as diabetes, cardiovascular complaint, cancer, etc. There's a huge global demand for medicinals that are both safe and effective moment. Scientists are now turning again to natural coffers as a possible source of drugs for the treatment and operation

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Nakamura, R. A., C. R. Monti, R. Ferrigno, F. A. Trevisan, L. N. Castilho, and J. A. Reinato. "Post-operative conformal radiotherapy on prostate cancer after radical prostatectomy. Results and dose constraint on bladder volume." Journal of Clinical Oncology 24, no. 18_suppl (2006): 14647. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.14647.

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14647 Background: To report on the results of post-operative conformal radiotherapy (3DCRT) on patients submitted to radical prostatectomy with high risk of biochemical failure or with biochemical failure. Methods: From July 1998 to December 2001, 40 patients with high risk of biochemical failure (T3 stage or positive margins) or with biochemical failure (PSA ≥ 0.2 ng/ml) after radical prostatectomy were submitted to 3DCRT on a single institution and were analyzed retrospectively. The median age was 65 years (52–74). The median pre-3DCRT PSA was 1.3 ng/ml (0–8.98). Twenty eight patients were s

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Al-fahham, Ali A., Naba Irfan Abbas, Muslim M. M. Jassim, and Lina S. Al-jameel. "Optical Density in Biochemistry: Principles and Applications in Analytical Methods: A Review." International Journal of Medical Science and Dental Health 11, no. 06 (2025): 62–69. https://doi.org/10.55640/ijmsdh-11-06-10.

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Optical density is one of the great principles of optics, expressed as the attenuation of light by a medium through which it passes. In most applications, it provides a critical link between the phenomena of light-matter interactions observed in such diverse fields as photonics, materials science, and nanotechnology. It therefore becomes a key parameter in biochemical analysis that links sample absorbance characteristics at given wavelengths quantitatively to desirable determinations for an array of laboratory applications. The measurement of optical density has recently been reported to becom

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Francolini, Giulio, Michele Ganovelli, Vanessa Di Cataldo, et al. "Early biochemical outcomes following PSMA-guided approach for biochemical relapse after prostatectomy: PSICHE trial." Journal of Clinical Oncology 41, no. 6_suppl (2023): 137. http://dx.doi.org/10.1200/jco.2023.41.6_suppl.137.

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137 Background: Main approach for early biochemical relapse (BR) after radical prostatectomy (RP) is prostate bed salvage radiotherapy (SRT). PSICHE is a prospective trial aimed to explore oncological results of a 68Ga-PSMA-11 PET/CT tailored strategy based on a pre-defined treatment algorithm. We present results focusing on early biochemical outcomes after therapy. Biochemical response was defined as Complete (CBR) or Partial (PBR) if a PSA < 0.2 or <50% of baseline was reached. Methods: Enrolled patients were affected by BR (defined as PSA > 0.2 ng/ml) after RP +/- postoperative SRT

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Behne, D., D. Alber, and A. Kyriakopoulos. "Selenium research in mammals using nuclear analytical methods and related techniques in conjunction with biochemical procedures." Journal of Radioanalytical and Nuclear Chemistry 259, no. 3 (2004): 435–39. http://dx.doi.org/10.1023/b:jrnc.0000020914.98944.08.

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Romero-Gameros, Carlos Alfonso, Baldomero González-Virla, Guadalupe Vargas-Ortega, et al. "Efficiency and Safety of CyberKnife Robotic Radiosurgery in the Multimodal Management of Patients with Acromegaly." Cancers 15, no. 5 (2023): 1438. http://dx.doi.org/10.3390/cancers15051438.

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Objective: To analyze, in a cohort of acromegalic patients, the results of the efficiency and safety of radiosurgery (CyberKnife), as well as the prognostic factors associated with disease remission. Material and methods: Observational, retrospective, longitudinal, and analytical study that included acromegalic patients with persistent biochemical activity after initial medical–surgical treatment, who received treatment with CyberKnife radiosurgery. GH and IGF-1 levels at baseline after one year and at the end of follow-up were evaluated. Results: 57 patients were included, with a median follo

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Lee, Emerson, Tanmay Singh, Misop Han, et al. "Early initiation of salvage radiotherapy is associated with improved metastasis-free survival in patients with relapsed prostate cancer following prostatectomy." Journal of Clinical Oncology 40, no. 6_suppl (2022): 262. http://dx.doi.org/10.1200/jco.2022.40.6_suppl.262.

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262 Background: Salvage radiation therapy is a recognized management option for patients who develop biochemical failure following radical prostatectomy. However, given the documented long natural history of biochemically relapsed prostate cancer after prostatectomy, questions remain on the value of early salvage intervention vs initial expectant management, especially with regards to more critical clinical rather than biochemical endpoints. We sought to determine the impact of early salvage radiotherapy (initiated at PSA 0.2 - 0.5 ng/ml) on metastasis-free survival in patients who receive sal

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Warne, David J., Ruth E. Baker, and Matthew J. Simpson. "Simulation and inference algorithms for stochastic biochemical reaction networks: from basic concepts to state-of-the-art." Journal of The Royal Society Interface 16, no. 151 (2019): 20180943. http://dx.doi.org/10.1098/rsif.2018.0943.

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Stochasticity is a key characteristic of intracellular processes such as gene regulation and chemical signalling. Therefore, characterizing stochastic effects in biochemical systems is essential to understand the complex dynamics of living things. Mathematical idealizations of biochemically reacting systems must be able to capture stochastic phenomena. While robust theory exists to describe such stochastic models, the computational challenges in exploring these models can be a significant burden in practice since realistic models are analytically intractable. Determining the expected behaviour

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Lang, E. "Section 7: Bioinformatics: Bioinformatics and its Impact on Clinical Research Methods." Yearbook of Medical Informatics 15, no. 01 (2006): 104–6. http://dx.doi.org/10.1055/s-0038-1638478.

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SummaryTo summarize current excellent research in the field of bioinformatics.Synopsis of the articles selected for the IMIA Yearbook 2006. Results: Current research in the field of bioinformatics clearly shows ongoing unification of experimental findings and clinical outcomes. Microarray data, gene sequences and clinical data are more and more perceived as different but related facets of one entity. Significant work is done in the area of text and data mining in order to bring together patient data and biochemical phenomena by means of ontologies. A strong trend in the clinical field is perfo

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Gao, Zhouyang, Jiangxia Zheng, and Guiyun Xu. "Research Progress and Technological Application Prospects of Comprehensive Evaluation Methods for Egg Freshness." Foods 14, no. 9 (2025): 1507. https://doi.org/10.3390/foods14091507.

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Eggs, recognized as a “complete nutritional food”, constitute a crucial source of high-quality protein and maintain an essential position in China’s animal protein supply system. However, extended storage periods induce biochemical degradation, including protein denaturation, air cell expansion, and microbial growth, substantially affecting both food safety and nutritional value. As consumer demand for food quality assurance increases, research in egg freshness evaluation has made substantial progress. While existing studies have focused on isolated detection methods for egg freshness, there r

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Bolla, Michel, Philippe Maingon, Christian Carrie, et al. "Short Androgen Suppression and Radiation Dose Escalation for Intermediate- and High-Risk Localized Prostate Cancer: Results of EORTC Trial 22991." Journal of Clinical Oncology 34, no. 15 (2016): 1748–56. http://dx.doi.org/10.1200/jco.2015.64.8055.

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Purpose Up to 30% of patients who undergo radiation for intermediate- or high-risk localized prostate cancer relapse biochemically within 5 years. We assessed if biochemical disease-free survival (DFS) is improved by adding 6 months of androgen suppression (AS; two injections of every-3-months depot of luteinizing hormone–releasing hormone agonist) to primary radiotherapy (RT) for intermediate- or high-risk localized prostate cancer. Patients and Methods A total of 819 patients staged: (1) cT1b-c, with prostate-specific antigen (PSA) ≥ 10 ng/mL or Gleason ≥ 7, or (2) cT2a (International Union

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Kulikova, M. G., M. V. Belyakov, and A. A. Gerts. "Quality control of malt by photoluminescent method." Sovremennaya nauka i innovatsii, no. 3 (39) (2022): 140–49. http://dx.doi.org/10.37493/2307-910x.2022.3.13.

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Malting is one of the most important stages in the production of brewing products. It is very long and can take place within 7-10 days, during which time the seeds used are converted directly into finished raw materials, malt. This period is characterized by the course of complex biochemical processes taking place in the grain and that is why it is especially demanding for express and high-precision quality control. To meet such needs, it is necessary to introduce modern methods of quality assessment, for example, the photoluminescent analysis method. Such a technological solution will make it

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Álvarez, Carlos, Lara Morán, Derek F. Keenan, Anne-Maria Mullen, and Gonzalo Delgado-Pando. "Mechanical and Biochemical Methods for Rigor Measurement: Relationship with Eating Quality." Journal of Food Quality 2019 (June 13, 2019): 1–13. http://dx.doi.org/10.1155/2019/1894543.

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Meat quality parameters are affected by a complex series of interacting chemical, biochemical, physical, and physiological components that determine not only the suitability for consumption and the conditions for further processing and storage but also consumer acceptability. Deep understanding and careful manipulation of these intrinsic and extrinsic factors have to be taken in account to ensure high quality of meat, with better technological properties and increased safety for consumers. Among meat quality characteristics, meat tenderness has been perceived as the most important factor gover

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Anikina, Oksana V., and Irina V. Kim. "Creating and evaluating new potato genotypes using traditional breeding methods." Far Eastern Agrarian Herald 18, no. 1 (2024): 5–15. http://dx.doi.org/10.22450/1999-6837-2024-18-1-5-15.

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The paper presents a comparative evaluation of economically important traits of potato variety collection. Selected genotypes were included in directed crossbreeding. New hybrid combinations with the most significant parameters were created for potato breeding. The research was carried out in a breeding field plot of Federal Scientific Center of Agricultural Biotechnology of the Far East named after A. K. Chaika, Putsilovka, Ussuriysk district, Primorsky krai. The research was based on the methodology developed by Federal Potato Research Center named after A. G. Lorkh and the All-Russian Insti

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Guo, Xiaorui. "Utilization of New Methods for Antibody Drug Conjugates: Research Progress and Future Prospects." Transactions on Materials, Biotechnology and Life Sciences 3 (March 24, 2024): 658–62. http://dx.doi.org/10.62051/11qfks06.

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Cancer has become an obvious health problem and scientists focus on this to help the problem. Antibody drug conjugates (ADC) has been considered as an efficient way to treat cancer. There are already many ways to produce ADC, but traditional methods need long and complicated biochemical process. Synthesis methods with high efficiency need to be found. This article aimed to describe three new methods for ADC synthesis, and it came out that all these three methods have high quality and can be used as a common technology to produce ADC. Also, the safety of ADC and several examples of clinical use

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Kind, Felix, Thomas F. Fassbender, Geoffroy Andrieux, Melanie Boerries, Philipp T. Meyer, and Juri Ruf. "Early PSA Change after [177Lu]PSMA-617 Radioligand Therapy as a Predicator of Biochemical Response and Overall Survival." Cancers 14, no. 1 (2021): 149. http://dx.doi.org/10.3390/cancers14010149.

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Purpose: Radioligand therapy with [177Lu]PSMA-617 (PSMA-RLT) is a promising therapeutic option for metastatic castration-resistant prostate cancer (mCPRP). This study assessed the prognostic value of early PSA measurements during PSMA-RLT. Methods: 27 patients with mCRPC scheduled for PSMA-RLT were prospectively enrolled for a serial short-interval PSA-assessment. Change in PSA (∆%PSA) during two treatment cycles was correlated with biochemical response (BR) and change in tumor volume on PET (TV) after 16 weeks (w16), as well as overall survival (OS). PCWG3 criteria and the recently recommende

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Nakamura, R. A., C. R. Monti, F. A. Trevisan, et al. "Delaying conformal radiation therapy in high-risk prostate cancer patients lowers the actuarial distant metastases free survival." Journal of Clinical Oncology 25, no. 18_suppl (2007): 15614. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.15614.

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15614 Background: It is not well documented on medical literature the value of time to treat prostate cancer. This study was performed to evaluate the value of treatment time with conformal radiotherapy (3DCRT) in high-risk prostate cancer patients. Methods: From October 1997 to January 2002, 116 patients with high-risk prostate cancer were submitted to 3DCRT and were analyzed retrospectively. The median age was 65 years-old. High risk patients were defined as patients with PSA > 20 ng/ml, and/or T3 clinical stage and/or Gleason score > 7, or two factors of intermediate risk (PSA >= 1

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Meenakshi, Suresh, Kakade Kaushiki, and Khodade Khushi. "Biochemical test for identification of proteins by biuret reagent using microscale methods." i-manager's Journal on Life Sciences 3, no. 1 (2024): 6. http://dx.doi.org/10.26634/jls.3.1.20938.

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This research paper explores the qualitative analysis of protein samples using the Biuret reagent through microscale methods involving ceramic tiles, grooved tiles, and Eppendorf tubes. The study highlights the advantages of minimal reagent usage, reduced waste, and enhanced safety. The Biuret test is employed to detect peptide bonds indicative of protein presence. Protein concentrations used for the identity assay ranged from 0.1% to 1.0%. Protein was detected by all three methods compared; however, the Eppendorf method detected proteins at a concentration of 0.3% and above. The ceramic and g

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Peddada, Suneal Gopal, Craig Oliver, Angela Phelps, Steven H. Stokes, and Jarrod Bartlett Adkison. "Post-prostatectomy salvage radiation therapy in prostate cancer upon identification of biochemical failure." Journal of Clinical Oncology 34, no. 2_suppl (2016): 127. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.127.

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127 Background: Prostate Specific Antigen (PSA) values post-prostatectomy are used as an indication for salvage radiation therapy. It has been suggested that initiation of therapy at lower PSA values lead to better outcomes. This study investigates outcomes of salvage radiation therapy at specific PSA thresholds. Methods: One hundred two prostate cancer patients were treated with salvage radiotherapy at our institution with curative intent, 19 of whom had Gleason score ≤6, 52 of whom had Gleason 7, and 31 with Gleason ≥8. Median follow-up after radiotherapy was 51 months. The median PSA prior

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Loeb, Stacy, Yasin Folkvaljon, David Robinson, Thorsten Schlomm, Hans Garmo, and Pär Stattin. "Phosphodiesterase type 5 inhibitors (PDE5i) and prostate cancer recurrence." Journal of Clinical Oncology 34, no. 2_suppl (2016): 55. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.55.

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55 Background: Phosphodiesterase type 5 inhibitors are commonly used for management of erectile dysfunction after prostate cancer (CaP) treatment. Single-institution studies have reported conflicting data on PDE5i use and recurrence after radical prostatectomy (RP). We re-evaluated the association between PDE5i use after RP and RT with biochemical recurrence in a nationwide, population-based registry. Methods: We performed a nested case-control study using data from the National Prostate Cancer Register of Sweden (including >98% prostate cancer cases nationwide), linked to the national Pres

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Melo, N., C. Hobday, M. Dowsett, et al. "Oestrogen receptor (ER) analysis in B-cell chronic lymphocytic leukemia: Correlation of biochemical and immunocytochemical methods." Leukemia Research 14, no. 11-12 (1990): 949–52. http://dx.doi.org/10.1016/0145-2126(90)90106-j.

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Molino, A., R. Micciolo, M. Turazza, et al. "Prognostic significance of estrogen receptors in 405 primary breast cancers: a comparison of immunohistochemical and biochemical methods." Breast Cancer Research and Treatment 45, no. 3 (1997): 241–49. http://dx.doi.org/10.1023/a:1005769925670.

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Muller, Don, and Paul Monsour. "Prostate brachytherapy implant quality on biochemical control." Journal of Clinical Oncology 33, no. 7_suppl (2015): 128. http://dx.doi.org/10.1200/jco.2015.33.7_suppl.128.

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128 Background: prostate brachytherapy at our institution was analyzed for implant quality on biochemical control. Methods: We treated 368 patients with clinically localized prostate cancer. All patients underwent 1 month CT based dosimetric analysis. Follow up data was available on 289 patients with a minimum follow up of 5 years. Gleason score was 6 in 80% (n=233), and 7 in 20% (n=56). Clinical stage was T1c in 90% of cases (n=260), T2a was 8% (n=23), T2b was <1% (n=3), T2c was < 1% (n=2). The initial prostate-specific antigen was < 10 ng/ml in 95% (n=274), 10.1-20 ng/ml in 5% (15).

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