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Journal articles on the topic 'Biochemical toxicology'

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1

Fry, Jeffrey R. "Book Review: Biochemical Toxicology." Alternatives to Laboratory Animals 14, no. 4 (June 1987): 397. http://dx.doi.org/10.1177/026119298701400418.

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2

Vaidya, Vishal S., Kartik Shankar, Udayan M. Apte, Sharmilee P. Sawant, and Pallavi B. Limaye. "Introduction to Biochemical Toxicology." International Journal of Toxicology 20, no. 5 (September 2001): 331–33. http://dx.doi.org/10.1177/109158180102000511.

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3

Bridges, James W. "Frontiers in biochemical toxicology." Trends in Pharmacological Sciences 6 (January 1985): S11—S15. http://dx.doi.org/10.1016/0165-6147(85)90235-4.

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4

Wells, Peter G., and Louise M. Winn. "Biochemical Toxicology of Chemical Teratogenesis." Critical Reviews in Biochemistry and Molecular Biology 31, no. 1 (January 1996): 1–40. http://dx.doi.org/10.3109/10409239609110574.

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5

Marzin, D. "Biochemical toxicology: A practical approach." Biochimie 70, no. 2 (February 1988): 299. http://dx.doi.org/10.1016/0300-9084(88)90081-8.

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6

Hodgson, Ernest. "Biochemical toxicology: A practical approach." Analytical Biochemistry 167, no. 1 (November 1987): 210–11. http://dx.doi.org/10.1016/0003-2697(87)90154-0.

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7

Gibson, G. Gordon. "Biochemical toxicology: A practical approach." Trends in Pharmacological Sciences 8, no. 5 (May 1987): 195. http://dx.doi.org/10.1016/0165-6147(87)90169-6.

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8

Chipman, J. K. "Biochemical toxicology — A practical approach." Clinica Chimica Acta 168, no. 1 (September 1987): 119–20. http://dx.doi.org/10.1016/0009-8981(87)90278-6.

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9

Guengerich, F. Peter. "Life and Times in Biochemical Toxicology." International Journal of Toxicology 24, no. 1 (January 2005): 5–21. http://dx.doi.org/10.1080/10915810590918670.

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The biochemical facets of toxicology have always had a major role in providing insight into mechanisms. Some of the history of the development of this area is summarized, including metabolism, enzymology, and the chemistry of reactive intermediates. Knowledge in these fields has had a major impact in the areas of drug metabolism and safety assessment, which are both critical steps in the development of pharmaceuticals and the rational use of commodity chemicals. The science of toxicology has developed considerably with input from other disciplines and today is poised to emerge as a predictive science with even more dramatic impact. The challenges ahead are considerable but there is renewed excitement in the potential of the field. As in the past, further advances in the field of toxicology will require the input of knowledge from many disciplines.
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10

Eisler, Ronald. "Aquatic Toxicology: Molecular, Biochemical, and Cellular Perspectives." Transactions of the American Fisheries Society 124, no. 5 (September 1, 1995): 786–87. http://dx.doi.org/10.1577/1548-8659-124.5.786.

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11

Forth, W. "Book Reviews : Toxicology of Metals- Biochemical Aspects." Human & Experimental Toxicology 15, no. 3 (March 1996): 277. http://dx.doi.org/10.1177/096032719601500321.

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12

Jensen, Arne. "Aquatic toxicology, molecular, biochemical and cellular perspectives." Journal of Experimental Marine Biology and Ecology 189, no. 1-2 (June 1995): 254–60. http://dx.doi.org/10.1016/0022-0981(95)90060-8.

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13

Turner, Paul. "Book Review: Biochemical Toxicology: A Practical Approach." Tropical Doctor 17, no. 4 (October 1987): 192. http://dx.doi.org/10.1177/004947558701700413.

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14

Wolfe, Douglas A. "Aquatic toxicology: Molecular, biochemical, and cellular perspectives." Aquatic Toxicology 32, no. 4 (July 1995): 355–56. http://dx.doi.org/10.1016/0166-445x(95)90019-o.

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15

Vijverberg, H. PM. "Book Review: Principles of Biochemical Toxicology (3rd edition)." Human & Experimental Toxicology 19, no. 3 (March 2000): 203. http://dx.doi.org/10.1191/096032700678827708.

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16

Fentem, Julia H. "Book Review: Principles of Biochemical Toxicology — Second Edition." Alternatives to Laboratory Animals 20, no. 4 (October 1992): 579–80. http://dx.doi.org/10.1177/026119299202000415.

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17

Chasseaud, L. F. "Biochemical Pharmacology and Toxicology, Vol. 1. Methodological enzymes." Trends in Pharmacological Sciences 7 (January 1986): 243–44. http://dx.doi.org/10.1016/0165-6147(86)90333-0.

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18

Silbergeld, E. K., and Y. Takeuchi. "Summary of Workshop: Biochemical Methods in Neurobehavioral Toxicology." Environmental Research 60, no. 1 (January 1993): 74–75. http://dx.doi.org/10.1006/enrs.1993.1013.

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19

Tormey, W. P., R. Srinivasan, and T. Moore. "Biochemical toxicology and suicide in Ireland: a laboratory study." Irish Journal of Medical Science 182, no. 2 (November 29, 2012): 277–81. http://dx.doi.org/10.1007/s11845-012-0879-5.

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20

Negro Silva, Luis Fernando, Christian Li, Paula Juliana Brizuela de Seadi Pereira, Wendy Tan, Michelle Dubuc-Mageau, Audrey Sanfacon, Roy Forster, Robert Tavcar, Andy Makin, and Simon Authier. "Biochemical and Electroretinographic Characterization of the Minipig Eye in the Context of Drug Safety Investigations." International Journal of Toxicology 38, no. 5 (August 30, 2019): 415–22. http://dx.doi.org/10.1177/1091581819867929.

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Minipigs are an emerging nonrodent alternative for ocular toxicology owing to anatomical similarities in the minipig eyes when compared to humans. Ocular structures and components from Göttingen minipigs were characterized and compared to species commonly used in toxicology. Ocular reference data from Göttingen minipig including intraocular pressure, vitreous electrolyte and thiol concentration, and electroretinography (ERG) data are essential to model characterization and data interpretation during drug safety assessments. Intravitreal positive control agents including gentamicin, indocyanine green, and glycine were used to demonstrate ERG alterations caused by retinal cell toxicity, light transmission obstruction, or neurotransmission interferences, respectively. Electrolyte concentrations of the aqueous and vitreous humors from Göttingen minipigs were similar to other species including humans. The reference data presented herein supports the use of the Göttingen minipig as an alternate nonrodent species in ocular toxicology.
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21

Packer, Melina. "Becoming with Toxicity: Chemical Epigenetics as “Racializing and Sexualizing Assemblage”." Hypatia 37, no. 1 (2022): 2–26. http://dx.doi.org/10.1017/hyp.2021.68.

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AbstractIn this article I think through Black feminism and queer theory to critically analyze toxicology. I focus on toxicology's conception of endocrine-disrupting chemicals (EDCs), a class of toxicants that can cause epigenetic changes leading to inheritable health issues. I suggest that Black feminist interventions are particularly necessary for the study of toxicants because multiply marginalized populations are disproportionately more exposed to EDCs. The structural preconditions that generate this uneven, racialized, and sexualized toxic body-burden threaten to turn cultural constructions of race and sex (epistemologies) into biological realities (ontologies). My discursive analysis of key scientific texts on toxicology, EDCs, and epigenetics underscores how Eurocentric biases and eugenic logics permeate and co-constitute biochemical matter. I further argue that these texts’ un/articulated norms regarding the human, sexual behavior, and evolutionary fitness undermine the usefulness of toxicological assessments for environmental justice. I close by urging scientist scholar-activists to reconceive the study of toxicants. A Black feminist approach to toxicity, I suggest, would not only situate chemical exposures in their sociopolitical contexts, but also radically revision what it means to be human.
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22

Sharma, Alok K., James P. Morrison, Deepa B. Rao, Ingrid D. Pardo, Robert H. Garman, and Brad Bolon. "Toxicologic Pathology Analysis for Translational Neuroscience." International Journal of Toxicology 35, no. 4 (March 24, 2016): 410–19. http://dx.doi.org/10.1177/1091581816636372.

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A half-day American College of Toxicology continuing education course presented key issues often confronted by translational neuroscientists when predicting human risk from animal-derived toxicologic pathology data. Two talks correlated discrete structures with major functions in brains of rodents and nonrodents. The third lecture provided practical advice to obtain highly homologous rodent brain sections for quantitative morphometry in developmental neurotoxicity testing. The last presentation discussed demographic influences (eg, species, strain, sex, age), physiological attributes (eg, body composition, brain vascularity, pharmacokinetic/pharmacodynamic patterns, etc), and husbandry parameters (eg, group housing) recognized to impact the actions of neuroactive chemicals. Speakers described common cases of real-world challenges to animal data interpretation encountered when designing studies or extrapolating biological responses across species. The efficiency of translational neuroscience efforts will likely be enhanced as new methods (eg, high-resolution non-invasive imaging) improve our capability to cross-connect subtle anatomic and/or biochemical lesions with functional changes over time.
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23

Anthony, Maria L., Kevin P. R. Gartland, Christopher R. Beddell, John C. Lindon, and Jeremy K. Nicholson. "Studies of the biochemical toxicology of uranyl nitratein the rat." Archives of Toxicology 68, no. 1 (1994): 43. http://dx.doi.org/10.1007/s002040050031.

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24

Wu, Z. W., X. Q. Yang, and Y. L. Zhang. "The Toxicology and Biochemical Characterization of Cantharidin on Cydia pomonella." Journal of Economic Entomology 108, no. 1 (January 8, 2015): 237–44. http://dx.doi.org/10.1093/jee/tou031.

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25

Netter, K. J. "Chronopharmacology — Cellular and biochemical interactions." Toxicology 61, no. 2 (April 1990): 211. http://dx.doi.org/10.1016/0300-483x(90)90022-9.

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26

Mebs, D. "Biochemical Basis of Chemical Carcinogenesis." Toxicon 23, no. 2 (January 1985): 355. http://dx.doi.org/10.1016/0041-0101(85)90163-1.

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27

Jones, Dennis. "Biochemical pharmacology of obesity." Trends in Pharmacological Sciences 6 (January 1985): 88–89. http://dx.doi.org/10.1016/0165-6147(85)90037-9.

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28

Orrenius, Sten. "Biochemical mechanisms of cytotoxicity." Trends in Pharmacological Sciences 6 (January 1985): S15—S20. http://dx.doi.org/10.1016/0165-6147(85)90236-6.

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29

Fuhrmann, G. F. "Handbook of experimental pharmacology, volume 115. Toxicology of metals. Biochemical aspects." Toxicology 108, no. 1-2 (April 1996): 153–54. http://dx.doi.org/10.1016/s0300-483x(96)03314-8.

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30

Tormey, William P. "Further to the evolution of best practice in forensic biochemical toxicology." Science & Justice 57, no. 2 (March 2017): 155. http://dx.doi.org/10.1016/j.scijus.2017.01.001.

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31

Anthony, Maria L., Kevin P. R. Gartland, Christopher R. Beddell, John C. Lindon, and Jeremy K. Nicholson. "Studies of the biochemical toxicology of uranyl nitrate in the rat." Archives of Toxicology 68, no. 1 (January 1994): 43–53. http://dx.doi.org/10.1007/s002040050028.

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32

BONDY, STEPHEN C. "The Biochemical Evaluation of Neurotoxic Damage." Toxicological Sciences 6, no. 2 (1986): 208–16. http://dx.doi.org/10.1093/toxsci/6.2.208.

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33

BONDY, S. "The biochemical evaluation of neurotoxic damage." Fundamental and Applied Toxicology 6, no. 2 (February 1986): 208–16. http://dx.doi.org/10.1016/0272-0590(86)90234-4.

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34

Akarapipad, Patarajarin, Kattika Kaarj, Yan Liang, and Jeong-Yeol Yoon. "Environmental Toxicology Assays Using Organ-on-Chip." Annual Review of Analytical Chemistry 14, no. 1 (June 5, 2021): 155–83. http://dx.doi.org/10.1146/annurev-anchem-091620-091335.

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Adverse effects of environmental toxicants to human health have traditionally been assayed using in vitro assays. Organ-on-chip (OOC) is a new platform that can bridge the gaps between in vitro assays (or 3D cell culture) and animal tests. Microenvironments, physical and biochemical stimuli, and adequate sensing and biosensing systems can be integrated into OOC devices to better recapitulate the in vivo tissue and organ behavior and metabolism. While OOCs have extensively been studied for drug toxicity screening, their implementation in environmental toxicology assays is minimal and has limitations. In this review, recent attempts of environmental toxicology assays using OOCs, including multiple-organs-on-chip, are summarized and compared with OOC-based drug toxicity screening. Requirements for further improvements are identified and potential solutions are suggested.
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35

Hollenberg, M. D. "Biochemical mechanisms of receptor regulation." Trends in Pharmacological Sciences 6 (January 1985): 299–302. http://dx.doi.org/10.1016/0165-6147(85)90137-3.

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36

Foye, William O. "Medicinal chemistry, a biochemical approach." Trends in Pharmacological Sciences 6 (January 1985): 488. http://dx.doi.org/10.1016/0165-6147(85)90230-5.

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37

Gibson, G. Gordon. "Biochemical pharmacology and toxicology volume 1, methodological aspects of drug metabolizing enzymes." FEBS Letters 202, no. 1 (June 23, 1986): 168. http://dx.doi.org/10.1016/0014-5793(86)80680-9.

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38

Patterson, Andrew D., and Peter J. Turnbaugh. "Microbial Determinants of Biochemical Individuality and Their Impact on Toxicology and Pharmacology." Cell Metabolism 20, no. 5 (November 2014): 761–68. http://dx.doi.org/10.1016/j.cmet.2014.07.002.

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39

Duffel, Michael W. "Biochemical Pharmacology and Toxicology. Vol. I. Methodological Aspects of Drug Metabolizing Enzymes." Journal of Pharmaceutical Sciences 75, no. 7 (July 1986): 727. http://dx.doi.org/10.1002/jps.2600750730.

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40

Bieber, A. L., J. P. Mills, C. Ziolkowski, and J. Harris. "Rattlesnake Neurotoxins: Biochemical and Biological Aspects." Journal of Toxicology: Toxin Reviews 9, no. 2 (January 1990): 285–306. http://dx.doi.org/10.3109/15569549009033117.

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41

SFORCIN, J. M., S. R. C. FUNARI, and E. L. B. NOVELLI. "SERUM BIOCHEMICAL DETERMINATIONS OF PROPOLIS-TREATED RATS." Journal of Venomous Animals and Toxins 1, no. 1 (1995): 31–37. http://dx.doi.org/10.1590/s0104-79301995000100005.

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42

Dokmetjian, José Christian, Sergio del Canto, Sabrina Vinzón, and Mirtha Biscoglio de Jiménez Bonino. "Biochemical characterization of the Micrurus pyrrhocryptus venom." Toxicon 53, no. 3 (March 2009): 375–82. http://dx.doi.org/10.1016/j.toxicon.2008.12.015.

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43

Hirst, Charlotte, Emma Dalton-Brown, Sophie Regan, Craig Benson, Amy Mercer, Dan Carr, James Maggs, et al. "Biochemical and toxicological consequences of methapyrilene bioactivation." Toxicology 240, no. 3 (November 2007): 154–55. http://dx.doi.org/10.1016/j.tox.2007.06.076.

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44

Nolan, C. V., and Z. A. Shaikh. "Lead nephrotoxicity and associated disorders: biochemical mechanisms." Toxicology 73, no. 2 (January 1992): 127–46. http://dx.doi.org/10.1016/0300-483x(92)90097-x.

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45

Upreti, Kaushal K., Mukul Das, Arvind Kumar, Giriraj B. Singh, and Subhash K. Khanna. "Biochemical toxicology of argemone oil. IV short-term oral feeding response in rats." Toxicology 58, no. 3 (October 1989): 285–98. http://dx.doi.org/10.1016/0300-483x(89)90142-x.

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46

Roper, Jason, Elizabeth A. Lipscomb, Jay S. Petrick, Rakesh Ranjan, Alaina Sauve-Ciencewicki, and Laurie Goodwin. "Toxicological Assessment of Newly Expressed Proteins (NEPs) in Genetically Modified (GM) Plants." Journal of Regulatory Science 9, no. 1 (January 5, 2021): 61–66. http://dx.doi.org/10.21423/jrs-v09i1roper.

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This paper details the weight of evidence (WOE) and stepwise approaches used to assess the food and feed safety of newly expressed proteins (NEPs) in genetically modified (GM) plants, based on previously reported principles. The WOE approach is critical, as in a vast majority of cases no single assay or biochemical characteristic can identify a protein as a hazard. A stepwise approach is recommended to evaluate the safety of NEPs taking the totality of information into account. Potential triggers for the need for supplementary toxicology studies are discussed, and an alternative in vitro method for the acute toxicology study is proposed. doi: 10.21423/jrs-v09i1roper
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47

Ouf, Salama A., Jahanzaib Rasheed, Kafeel Ahmad, Zafar Iqbal Khan, Kinza Wajid, Muhammad Nadeem, Shahwana Tehreem, et al. "Nutritional Imbalance, Toxicology and Deficiency Potential of Livestock." Revista de Chimie 71, no. 11 (December 4, 2020): 51–62. http://dx.doi.org/10.37358/rc.20.11.8373.

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This study investigated the changes in the enzymatic and biochemical profiles of lactating, non-lactating, and young buffaloes during different sampling. In the present research thirty buffaloes (Nili-Ravi) were selected and divided into three categories lactating, non-lactating, and young. Four samplings were performed in different seasons (summer, autumn, winter, and spring), and 10 blood serum samples were collected from each category of Nili-Ravi buffaloes during each sampling period. Higher glucose, urea, creatinine, and mycotoxins (AFB1, ZEA, OTA) values were found during summer sampling season, higher SGPT (ALT) and SGOT (AST) values were found during the autumn season, higher cholesterol, alkaline phosphatase and uric acid values were found during the winter season.
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48

Cotgreave, I. A., P. Moldeus, and S. Orrenius. "Host Biochemical Defense Mechanisms Against Prooxidants." Annual Review of Pharmacology and Toxicology 28, no. 1 (April 1988): 189–212. http://dx.doi.org/10.1146/annurev.pa.28.040188.001201.

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49

Needleman, P., E. H. Blaine, J. E. Greenwald, M. L. Michener, C. B. Saper, P. T. Stockmann, and H. E. Tolunay. "The Biochemical Pharmacology of Atrial Peptides." Annual Review of Pharmacology and Toxicology 29, no. 1 (April 1989): 23–54. http://dx.doi.org/10.1146/annurev.pa.29.040189.000323.

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50

Gupta, P. K. "Malathion Induced Biochemical Changes in Rats." Acta Pharmacologica et Toxicologica 35, no. 3 (March 13, 2009): 191–94. http://dx.doi.org/10.1111/j.1600-0773.1974.tb00738.x.

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