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Journal articles on the topic 'Biochemistry Laboratory'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 February 2022

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1

Jovičić, Snežana, and Nada Majkić-Singh. "Medical Biochemistry as Subdiscipline of Laboratory Medicine in Serbia." Journal of Medical Biochemistry 36, no. 2 (April 1, 2017): 177–86. http://dx.doi.org/10.1515/jomb-2017-0010.

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SummaryMedical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia, and medical biochemist is the official name for the clinical chemist (or clinical biochemist). This is the largest sub-discipline of the laboratory medicine in Serbia. It includes all aspects of clinical chemistry, and also laboratory hematology with coagulation, immunology, etc. Medical biochemistry laboratories in Serbia and medical biochemists as a profession are part of Health Care System and their activities are regulated through: the Health Care Law and rules issued by the Chamber of Medical Biochemists of Serbia. The first continuous and organized education for Medical Biochemists (Clinical Chemists) in Serbia dates from 1945, when the Department of Medical Biochemistry was established at the Pharmaceutical Faculty in Belgrade. In 1987 at the same Faculty a five years undergraduate study program was established, educating Medical Biochemists under a special program. Since the academic year 2006/2007 the new five year undergraduate (according to Bologna Declaration) and four-year postgraduate program according to EC4 European Syllabus for Postgraduate Training in Clinical Chemistry and Laboratory Medicine has been established. The Ministry of Education and Ministry of Public Health accredited these programs. There are four requirements for practicing medical biochemistry in the Health Care System: University Diploma of the Faculty of Pharmacy (Study of Medical Biochemistry), successful completion of the professional exam at the Ministry of Health after completion of one additional year of obligatory practical training in the medical biochemistry laboratories, membership in the Serbian Chamber of Medical Biochemists and licence for skilled work issued by the Serbian Chamber of Medical Biochemists. In order to present laboratory medical biochemistry practice in Serbia this paper will be focused on the following: Serbian national legislation, healthcare services organization, sub-disciplines of laboratory medicine and medical biochemistry as the most significant, education in medical biochemistry, conditions for professional practice in medical biochemistry, continuous quality improvement, and accreditation. Serbian healthcare is based on fundamental principles of universal health coverage and solidarity between all citizens.

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2

Majkić-Singh, Nada. "Education and Recognition of Professional Qualifications in the Field of Medical Biochemistry in Serbia." Journal of Medical Biochemistry 30, no. 4 (October 1, 2011): 279–86. http://dx.doi.org/10.2478/v10011-011-0013-7.

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Education and Recognition of Professional Qualifications in the Field of Medical Biochemistry in Serbia Medical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia, and medical biochemist is the official name for the clinical chemist (or clinical biochemist). This is the largest sub-discipline of the laboratory medicine in Serbia. It includes all aspects of clinical chemistry, and also laboratory hematology with coagulation, immunology, etc. Medical biochemistry laboratories in Serbia and medical biochemists as a profession are part of Health Care System and their activities are regulated through: the Health Care Law and rules issued by the Chamber of Medical Biochemists of Serbia. The first continuous and organized education for Medical Biochemists (Clinical Chemists) in Serbia dates from 1945, when the Department of Medical Biochemistry was established at the Pharmaceutical Faculty in Belgrade. In 1987 at the same Faculty a five years undergraduate branch was established, educating Medical Biochemists under a special program. Since school-year 2006/2007 the new five year undergraduate (according to Bologna Declaration) and postgraduate program of four-year specialization according to EC4 European Syllabus for Post-Gradate Training in Clinical Chemistry and Laboratory Medicine has been established. The Ministry of Education and Ministry of Public Health accredits the programs. There are four requirements for practicing medical biochemistry in the Health Care System: University Diploma of the Faculty of Pharmacy (Study of Medical Biochemistry), successful completion of the profession exam at the Ministry of Health after completion of one additional year of obligatory practical training in the medical biochemistry laboratories, membership in the Serbian Chamber of Medical Biochemists and licence for skilled work issued by the Serbian Chamber of Medical Biochemists. The process of recognition of a foreign higher education document for field of medical biochemistry is initiated on request by Candidate. The process of recognition of foreign higher education documents is performed by the University. In the process of recognition in Serbia national legislations are applied as well as international legal documents of varying legal importance.

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3

Majkic-Singh, Nada. "Society of medical biochemists of Serbia and Montenegro: 50 years anniversary." Jugoslovenska medicinska biohemija 24, no. 3 (2005): 157–70. http://dx.doi.org/10.2298/jmh0503157m.

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Medical biochemistry (synonyms: clinical chemistry or clinical biochemistry) in the terms of professional and scientific discipline, stems from and/or has developed along with the natural sciences and its influences (mathematics, physics, chemistry and biochemistry) and medical sciences as well (physiology, genetics, cell biology). As a scientific discipline, medical biochemistry studies metabolic processes of physiological and pathological changes with humans and animals. Applying analytical chemistry's and biochemistry's techniques enables medical biochemists to gain plenty of information related to diagnosis and prognosis which serve physicians to asses the gravity of illness and prescribe healing therapy. Therefore medical biochemistry is an integral part of modern medicine. This discipline was dubbed various, often confusing names such as pathology, physiology, clinical biology, clinical pathology, chemical pathology, clinical biochemistry, medical biochemistry, clinical chemistry and laboratory medicine, all depending on place of origin. The official, internationally accepted name - clinical chemistry, was mentioned for the first time in 1912 by Johan Scherer, who described his laboratory as Clinical Chemistry Laboratory (Klinisch Chemische Laboratorium) in the hospital Julius in Wurzburg in Germany. After creating national societies of clinical chemists, Professor Earl J. King of Royal Postgraduate Medical School from London incited an initiative to unite national societies into the organization with worldwide character - it was the International Association of Clinical Biochemists, monitored by the International Union for Pure and Applied Chemistry (IUPAC). On 24 July 1952 in Paris, a Second International Congress of Biochemistry was held. A year later, in Stockholm, the name of a newly formed association was altered into International Federation of Clinical Chemistry, which was officially accepted in 1955 in Brussels. Today this federation-s name is International Federation for Clinical Chemistry and Laboratory Medicine (IFCC). Right after the World War II our medical biochemists began to gather within their expert societies. Even before 1950 Pharmaceutical Society of Serbia hosted laboratory experts among whom the most active were Prof. Dr. Aleksandar Damanski for bromatology, Prof. Dr. Momcilo Mokranjac for toxicology and Docent Dr. Pavle Trpinac for biochemistry. When the Managing Board of the Pharmaceutical Society of National Republic of Serbia held its session on 22 December 1950, an issue was raised with reference to creation of a Section that would gather together the laboratory experts. Section for Sanitary Chemistry, combining all three profiles of laboratory staff, i.e. medical biochemists, sanitary chemists and toxicologists, was founded on 1st of January 1951. On 15 May 1955, during the sixth plenum of the Society of Pharmaceutical Societies of Yugoslavia (SFRY) held in Split, the decision was passed to set up a Section for Medical Biochemistry in SFDJ. The Section for Medical Biochemistry in SFDJ was renamed into Society for Medical Biochemistry of SFDJ based on the decision passed during the 16th plenum of SFDJ, held on 15 May 1965 in Banja Luka. Pursuant to the decision passed by SMBY on 6 April 1995 and based on the historic data, 15 May was declared as being the official Day of the Society of Medical Biochemists of Yugoslavia. The purpose of YuSMB (currently SMBSCG) is to gather medical biochemists who would develop and enhance all the branches of medical biochemistry in health industry. Its tasks are as following: to standardize operations in clinical-biochemical laboratories, education of young biochemists on all levels, encouraging scientific research, setting up of working norms and implementation, execution and abiding by the ethics codices with health workers. SMBSCG is to promote the systemized standards in the field of medical biochemistry with the relevant federal and republican institutions. SMBSCG is to enable exchange of experiences of its members with the members of affiliate associations in the country and abroad. .

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4

Freitas-Rego, F. R., M. G. Pereira, S. O. Loureiro, M. T. de Santana, R. G. Garrido, and F. de S. R. G. Garrido. "Biochemistry: from supermarket to laboratory." Revista de Ensino de Bioquímica 5, no. 2 (May 25, 2007): 21. http://dx.doi.org/10.16923/reb.v5i2.109.

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5

OOIZUMI, TOORU. "3. Laboratory course of biochemistry." NIPPON SUISAN GAKKAISHI 83, no. 5 (2017): 846. http://dx.doi.org/10.2331/suisan.wa2435-4.

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6

Saunders, K. B. "Laboratory Instrumentation in Clinical Biochemistry." Journal of the Royal Society of Medicine 91, no. 1 (January 1998): 58–59. http://dx.doi.org/10.1177/014107689809100131.

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7

Adiga, Usha, and A. Preethika. "Errors in Clinical Biochemistry Laboratory." British Journal of Medicine and Medical Research 14, no. 8 (January 10, 2016): 1–6. http://dx.doi.org/10.9734/bjmmr/2016/25012.

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8

Boyer, Rodney F. "A proposal for biochemistry laboratory." Biochemical Education 14, no. 1 (January 1986): 12–14. http://dx.doi.org/10.1016/0307-4412(86)90006-3.

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9

Aksoy, Hilal, Abdullah Ozturk, Dilek Tarhan, Ibrahim Dolukup, and Duygu Ayhan Baser. "Biochemistry laboratory errors and patient safety: Turkey data." Turkish Journal of Biochemistry 46, no. 4 (August 1, 2021): 377–85. http://dx.doi.org/10.1515/tjb-2020-0193.

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Abstract Objectives Our aim in this study is to provide information about the rate of errors in the process of the biochemistry laboratories in the hospitals in Turkey with the “Indicators”. Methods The hospitals calculate their own data according to the indicator cards defined by the Ministry of Health of Turkey and enter into the system once in a year. In this study we examined the quality indicators related to the disruptions in the biochemistry laboratory of hospitals for the year of 2018. Results All indicators except “Non-timely reported result rate in biochemistry laboratory” are found to be significantly higher in university hospitals. This indicator is found to be significantly higher in private hospitals(p:0.030) “Lost sample rate in biochemistry laboratory” is found to be significantly higher in Eastern Anatolia Region (p:0.000) and “Non-timely reported result rate in biochemistry laboratory” is found to be significantly higher in Aegean Region (p:0.008). Conclusions The ratio of non-timely reported result rate is the most seen disruption in biochemistry laboratories. It may be due to lots of reasons; lack of biochemistry equipment, lack of staff, problems in transportation, etc. The management of hospitals and the staff should take measures and regulations about problems.

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10

Creanga, Iulian, Alexandra Totan, Olivera Lupescu, Iulia-Ioana Stanescu, Costin Dumitru, and Maria Greabu. "Aldolase - From Biochemistry to Laboratory Medicine." Revista de Chimie 70, no. 2 (March 15, 2019): 578–80. http://dx.doi.org/10.37358/rc.19.2.6959.

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Aldolase (ALD) (fructose-1,6-bisphosphate aldolase ) is a 160 kDa, enzyme which catalyzes the conversion of fructose 1-6-biphosphate in glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic metabolic pathway. There are also experimental data suggesting that nuclear ALD isoenzyme A might play an important role in cell proliferation. At the present time, the most useful serum markers of muscle injury following intense, prolonged exercise are: creatine kinase (CK), lactate dehydrogenase (LDH), aspartate aminotransferase myoglobin and troponin. Although serum ALD is not usually measured yet, it may be used together with CK to evaluate the status of muscle adaptation to training. Recent studies offered ALD a new perspective, as a future valuable biomarker in monitoring the evolution of muscle crush injuries, in order to prevent silent, but progressiv muscle fibers necrosis after injury. It has also been shown that ALD was an independent clinical prognostic marker in many other human cancers, being involved in some well-known signaling pathways.

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11

Vincent, John B., and Stephen A. Woski. "Cytochrome c: A Biochemistry Laboratory Course." Journal of Chemical Education 82, no. 8 (August 2005): 1211. http://dx.doi.org/10.1021/ed082p1211.

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12

Allison, Matthew J., and C. Larry Bering. "Immobilized Lactase in the Biochemistry Laboratory." Journal of Chemical Education 75, no. 10 (October 1998): 1278. http://dx.doi.org/10.1021/ed075p1278.

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13

Trindade, Vera Maria Treis, Geancarlo Zanatta, Pablo Ricardo Arantes, Iuri Dos Santos Blanco, Fernanda Paludo Demore, and Christianne Gazzana Salbego. "Virtual Laboratory Activities in Basic Biochemistry." Procedia - Social and Behavioral Sciences 106 (December 2013): 3329–34. http://dx.doi.org/10.1016/j.sbspro.2013.12.385.

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14

Craig, Paul A. "A Project-Oriented Biochemistry Laboratory Course." Journal of Chemical Education 76, no. 8 (August 1999): 1130. http://dx.doi.org/10.1021/ed076p1130.

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15

Dreisbach, Joseph H. "A problems-oriented biochemistry laboratory program." Journal of Chemical Education 63, no. 12 (December 1986): 1068. http://dx.doi.org/10.1021/ed063p1068.

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16

Garland, Matthew. "The practice laboratory — Part 2: biochemistry." Veterinary Nursing Journal 28, no. 3 (March 2013): 104–6. http://dx.doi.org/10.1111/vnj.12012.

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17

Wood, EJ. "Laboratory practical classes in biochemistry courses." Biochemical Education 18, no. 1 (January 1990): 9–12. http://dx.doi.org/10.1016/0307-4412(90)90006-a.

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18

Majkić-Singh, Nada. "Laboratory Medicine Management: Leadership Skills for Effective Laboratory." Journal of Medical Biochemistry 36, no. 3 (September 1, 2017): 207–10. http://dx.doi.org/10.1515/jomb-2017-0034.

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SummaryForum of the European Societies of Clinical Chemistry (FESCC) decided that the FESCC Symposium for Balkan Region would be held each year in Belgrade and organized by the Society of Medical Biochemists of Serbia and Montenegro (SMBSM). Professor Victor Blaton, at the time President of the FESCC, supported the organization of the Symposium. Purpose of these Symposia has been to educate clinical biochemists from Balkan region to improve management, leadership skills for effective laboratories. As a result of these decision twelve symposia have been organized thus far very successfully. Here the most important Symposium topics will be reviewed. Also, the 13thEFLM Symposium for Balkan Region under the title »Laboratory Medicine Management: Leadership Skills for Effective Laboratory«(Belgrade, September 2017) is organized by EFLM and SMBS under the Auspices of the International Federation of Clinical Chemistry (IFCC), Ministry of Education, Science and Technological Development of Serbia and Ministry of Health of Serbia with participation of the European and domestic specialists in field of Laboratory Medicine.

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19

Mulimani, V. H., and K. Dhananjay. "Immobilized alpha-Galactosidase in the Biochemistry Laboratory." Journal of Chemical Education 84, no. 12 (December 2007): 1974. http://dx.doi.org/10.1021/ed084p1974.

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20

Falk, Peter M. "Biochemistry laboratory for the freshman chemistry curriculum." Journal of Chemical Education 66, no. 11 (November 1989): 944. http://dx.doi.org/10.1021/ed066p944.

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21

Vestling, Martha M. "A peptide HPLC experiment for biochemistry laboratory." Journal of Chemical Education 68, no. 1 (January 1991): 72. http://dx.doi.org/10.1021/ed068p72.

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22

Erkoc, Figen, Aylin Sepici Dincel, Levent Kayrin, Yesim Ozkan, Subhan Eksioglu, Meral Yuksel, Goncagul Haklar, Ozlem Yavuz, Haydar Celik, and Muhsin Konuk. "The Multidisciplinary Approach to Biochemistry Laboratory Education." Turkish Journal of Biochemistry 38, no. 4 (2013): 506–12. http://dx.doi.org/10.5505/tjb.2013.02360.

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23

Verras, Peter, and Ronda Greaves. "Abnormal Laboratory Results: Interpreting paediatric biochemistry results." Australian Prescriber 28, no. 5 (October 1, 2005): 126–29. http://dx.doi.org/10.18773/austprescr.2005.096.

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24

Wolfson, Adele J., Mona L. Hall, and Thomas R. Branham. "An Integrated Biochemistry Laboratory, Including Molecular Modeling." Journal of Chemical Education 73, no. 11 (November 1996): 1026. http://dx.doi.org/10.1021/ed073p1026.

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25

Palmer, Richard E. "A kinetic experiment for the biochemistry laboratory." Journal of Chemical Education 63, no. 11 (November 1986): 1007. http://dx.doi.org/10.1021/ed063p1007.

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26

Furge, Laura Lowe, Rodney Boyer, and Adele J. Wolfson. "Innovation in the Biochemistry/Molecular biology laboratory." Biochemistry and Molecular Biology Education 43, no. 2 (February 25, 2015): 66–67. http://dx.doi.org/10.1002/bmb.20853.

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27

MacGillivray, A. J. "Laboratory techniques in biochemistry and molecular biology." FEBS Letters 224, no. 1 (November 16, 1987): 233. http://dx.doi.org/10.1016/0014-5793(87)80455-6.

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28

Klyushkin, I. V., K. T. Valeeva, and E. E. Krasnoshchekova. "Modern laboratory equipment." Kazan medical journal 74, no. 3 (June 15, 1993): 239–40. http://dx.doi.org/10.17816/kazmj64732.

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With the creation of new measuring instruments equipped with automation elements and powerful computer systems, the prospect of a qualitatively new level of laboratory diagnostics has arisen. Currently, large diagnostic laboratories are being equipped with equipment from well-known companies in Japan, USA, Germany, Austria, Switzerland. Research opportunities in the field of hematology, clinical biochemistry, immunology, microbiology have expanded significantly.

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29

Dreux, C., and Pr Y. Goussault. "Laboratory techniques in biochemistry and molecular biology. Applications of HPLC in biochemistry." Clinica Chimica Acta 172, no. 2-3 (March 1988): 342. http://dx.doi.org/10.1016/0009-8981(88)90341-5.

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30

Jørgensen, Per E. "Leadership and Management in Clinical Biochemistry." Journal of Medical Biochemistry 36, no. 3 (September 1, 2017): 216–19. http://dx.doi.org/10.1515/jomb-2017-0023.

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Summary Challenging times lay ahead for laboratory medicine in Europe due to at least three factors. 1) The scientific and technological developments increase the diagnostic possibilities but at the same time they will also change the interfaces among the different specialties of laboratory medicine. 2) The demographic changes with a more elderly population increase the demands for laboratory tests. 3) The increased complexity of the health care system combined with more well-informed patients calls for more coherent clinical pathways across the different sectors, for an increased focus on patient safety, and for a stronger involvement of patients and relatives. These issues cause both threats and opportunities for laboratory medicine – and they have to be handled in a situation with limited economic growth and shortage of money. This calls for a new organization of laboratory medicine in many hospitals as well as for a more active involvement of laboratory medicine in the clinical work and in the contact with the patients. Laboratory medicine will need dedicated and skillful leadership in order to prosper and grow during these challenging changes.

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31

Toffaletti, John G. "Blood Lactate: Biochemistry, Laboratory Methods, and Clinical Interpretation." Critical Reviews in Clinical Laboratory Sciences 28, no. 4 (January 1991): 253–68. http://dx.doi.org/10.3109/10408369109106865.

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32

Robyt, John F., and Bernard J. White. "Laboratory practical exams in the biochemistry lab course." Journal of Chemical Education 67, no. 7 (July 1990): 600. http://dx.doi.org/10.1021/ed067p600.

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33

Robinson, Arthur C. "An integrated approach to the undergraduate biochemistry laboratory." Biochemical Education 24, no. 4 (October 1996): 247. http://dx.doi.org/10.1016/s0307-4412(97)80797-2.

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34

Hakan Aydin, H., Ferhan K. Girgin, Biltan Ersoz, and Eser Sozmen. "Undergraduate laboratory work in biochemistry and new perspectives." Biochemical Education 27, no. 3 (July 1999): 160–61. http://dx.doi.org/10.1016/s0307-4412(99)00025-4.

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35

Bianco, Cristina Del, Domenica Torino, and Sheref S. Mansy. "Vesicle Stability and Dynamics: An Undergraduate Biochemistry Laboratory." Journal of Chemical Education 91, no. 8 (July 10, 2014): 1228–31. http://dx.doi.org/10.1021/ed400105q.

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36

Harman, James G., John A. Anderson, Richard A. Nakashima, and Robert W. Shaw. "An Integrated Approach to the Undergraduate Biochemistry Laboratory." Journal of Chemical Education 72, no. 7 (July 1995): 641. http://dx.doi.org/10.1021/ed072p641.

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37

Olukoga, A. O., J. Bolodeoku, and D. Donaldson. "Laboratory Instrumentation in Clinical Biochemistry: An Historical Perspective." Journal of the Royal Society of Medicine 90, no. 10 (October 1997): 570–77. http://dx.doi.org/10.1177/014107689709001013.

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38

Cornely, Kathleen, Eric Crespo, Michael Earley, Rachel Kloter, Aime Levesque, and Mary Pickering. "Kinetics of Papain: An Introductory Biochemistry Laboratory Experiment." Journal of Chemical Education 76, no. 5 (May 1999): 644. http://dx.doi.org/10.1021/ed076p644.

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39

Flurkey, William H. "An Inexpensive Gradient Maker for the Biochemistry Laboratory." Journal of Chemical Education 77, no. 8 (August 2000): 1041. http://dx.doi.org/10.1021/ed077p1041.

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40

Keck, Michael V. "DNA Topology Analysis in the Undergraduate Biochemistry Laboratory." Journal of Chemical Education 77, no. 11 (November 2000): 1471. http://dx.doi.org/10.1021/ed077p1471.

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41

Heron, Robert Campbell, and Wai Weldon Chiu. "Hydroxy-chloroquine Interference in Common Biochemistry Laboratory Assays." Journal of Applied Laboratory Medicine 5, no. 5 (June 30, 2020): 1130–37. http://dx.doi.org/10.1093/jalm/jfaa099.

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42

Cronholm, Jan-Olov Hoog, Dick Marte, Tomas. "Student attitudes towards laboratory exercises in medical biochemistry." Medical Teacher 22, no. 1 (January 2000): 30–33. http://dx.doi.org/10.1080/01421590078788.

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43

Furge, Laura, Adele Wolfson, and Rodney Boyer. "Commentary: Innovation in the biochemistry/molecular biology laboratory." Biochemistry and Molecular Biology Education 40, no. 1 (November 30, 2011): 23. http://dx.doi.org/10.1002/bmb.20575.

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Furge, Laura Lowe, Adele Wolfson, and Rodney Boyer. "Commentary: Innovation in the biochemistry/molecular biology laboratory." Biochemistry and Molecular Biology Education 41, no. 1 (January 2013): 11. http://dx.doi.org/10.1002/bmb.20664.

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45

Salman Ashraf, S. "Raising environmental awareness through applied biochemistry laboratory experiments." Biochemistry and Molecular Biology Education 41, no. 5 (September 2013): 341–47. http://dx.doi.org/10.1002/bmb.20717.

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46

Wolfson, Adele J., Laura Lowe Furge, and Rodney Boyer. "Commentary: Innovation in the biochemistry/molecular biology laboratory." Biochemistry and Molecular Biology Education 42, no. 1 (December 20, 2013): 39–40. http://dx.doi.org/10.1002/bmb.20759.

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Furge, Laura Lowe, Adele J. Wolfson, and Rodney Boyer. "Commentary: Innovation in the Biochemistry/Molecular Biology laboratory." Biochemistry and Molecular Biology Education 44, no. 2 (February 23, 2016): 117. http://dx.doi.org/10.1002/bmb.20945.

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48

Lefurgy, Scott T., and Emily C. Mundorff. "A 13-week research-based biochemistry laboratory curriculum." Biochemistry and Molecular Biology Education 45, no. 5 (March 2, 2017): 437–48. http://dx.doi.org/10.1002/bmb.21054.

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49

Wolfson, Adele J., and Rodney Boyer. "Commentary: Innovation in the Biochemistry/Molecular Biology Laboratory." Biochemistry and Molecular Biology Education 47, no. 3 (February 9, 2019): 219. http://dx.doi.org/10.1002/bmb.21217.

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50

Hall, Mona L., Christine A. Guth, Susan J. Kohler, and Adele J. Wolfson. "Advanced instrumentation projects for first-year biochemistry laboratory." Biochemistry and Molecular Biology Education 31, no. 2 (March 2003): 115–18. http://dx.doi.org/10.1002/bmb.2003.494031020194.

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