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Dissertations / Theses on the topic 'Biodegradation pathway'

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1

Kurt, Zohre. "Biodegradation of chlorinated compounds at interfaces and biodegradation of 4-nitroaniline." Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/50111.

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Most microbial activity in nature takes place at interfaces where redox discontinuities are present. Organic pollutants in groundwater encounter oxic/anoxic interfaces when they emerge to surface water bodies or volatilize above the plume. Such oxic/anoxic interfaces are key habitats for aerobic bacteria and are in turn created by the bacteria that degrade organic electron donors. In the absence of biodegradation, synthetic pollutants can migrate from the plume and impact a variety of receptors. The aims of our study were to determine whether microbes at oxic/anoxic interfaces can use syntheti
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2

Aemprapa, Sirinun. "Toluene/xylene catabolic pathway of Pseudomonas putida strain O←2C←2." Thesis, Bangor University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321526.

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3

Nakatsu, Cindy Hatsuyo Carleton University Dissertation Biology. "The biochemical pathway and catabolic genes for chlorobenzoate degradation encoded on the transposon Tn5271 of Alcaligenes SP. Strain BR60." Ottawa, 1992.

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4

Haddock, John David. "Biochemistry and genetics of the pathway for the anaerobic degradation of aromatic compounds by Eubacterium oxidoreducens." Diss., Virginia Tech, 1990. http://hdl.handle.net/10919/39756.

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The biochemical pathway for the anaerobic degradation of gallate, pyrogallol and phloroglucinol by Eubacterium oxidoreducens was investigated. Phloroglucinol reductase was purified 90-fold, from the soluble fraction of cell extract, to electrophoretic homogeneity. The enzyme was an α₂ homodimer with a native M<sub>r</sub> of 78,000, did not contain metals or cofactors and was specific for phloroglucinol and NADPH with a K<sub>m</sub> of 800 μM and 6.7 μM respectively at pH 6.8. The Km for phloroglucinol decreased with increasing pH. The enzyme catalyzed reaction was reversible and the equilib
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5

Hussain, Sabir. "Characterization of the isoproturon degrading community : from the field to the genes." Phd thesis, Université de Bourgogne, 2010. http://tel.archives-ouvertes.fr/tel-00674042.

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Frequent use of phenylurea herbicide isoproturon (IPU) in agricultural fields has resulted not only in the contamination of the natural resources including soil and water but also in the adaptation of the soil microflora to its rapid degradation. However, up to now, the mechanisms underlying this microbial adaptation are not well elucidated. The aim of this study was to explore the processes and factors implicated in IPU degradation from the agricultural field to the genes coding for catabolic genes. The study carried out at the experimental field of Epoisses cropped with a winter wheat / barl
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6

Ballaminut, Nara. "Caracterização do processo de descoloração de corante reativo diazo por basidiomicetos tropicais." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-23032017-164405/.

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Corantes reativos têxteis podem ser degradados por basidiomicetos, por meio de enzimas oxidativas e hidrolíticas, e compostos de baixa massa molar. Foi avaliada a descoloração de CI Reactive Blue 222 por Peniophora cinerea, Pleurotus ostreatus e Trametes villosa, selecionando condições ótimas para o processo e diferentes vias metabólicas foram observadas. A degradação foi confirmada por cromatografia de camada delgada. Foi sugerido que lacases de P. ostreatus oxidam o grupo cromóforo azo, ligado ao fenol, nas primeiras 24 horas, conjuntamente hidroxilização não enzimática. Lacases de P. cinere
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7

Oh, Mina. "Prediction of biodegradation pathways using knowledge base of enzymatic reactions." 京都大学 (Kyoto University), 2007. http://hdl.handle.net/2433/137124.

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8

Oliveira, Luciana de. "Avaliação da capacidade de biodegradação de benzeno, tolueno, etilbenzeno e isômeros de xileno por bactérias isoladas de área contaminada." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-02022018-160943/.

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Os compostos BTEX (benzeno, tolueno, etilbenzeno e xilenos) são os contaminantes mais frequentemente encontrados dentre os hidrocarbonetos de petróleo. A remoção destes compostos é dependente da atividade de uma população de micro-organismos adaptados capazes de promover a biodegradação dos mesmos. Neste estudo, foram utilizadas cinco cepas isoladas de área contaminada capazes de degradar estes compostos. As concentrações de BTEX foram determinadas por análises quantitativas realizadas por cromatografia gasosa com extração por headspace. Uma série de experimentos foi realizada para investigar
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9

Gupta, Ankit. "Mathematical Modeling of Reductive Transformation Kinetics of Branched Degradation Pathways of Groundwater Contaminants." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/45045.

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Groundwater contaminants such as chlorinated ethenes, chlorinated ethanes and nitroaromatic explosive compounds (e.g. 2,4,6-Trinitrotoluene (TNT)) degrade in the subsurface primarily by microbially catalyzed reductive transformation reactions. From a regulatory point of view, the capability to simulate the kinetics of these reductive transformation reactions coupled with other attenuation processes in the subsurface (e.g., sorption, advection, and dispersion) is required for site-specific solute transport models. A kinetic model based on Michaelis-Menten type equations (Widdowson 2004) has bee
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10

Menzies, Jennifer Z. "An Evaluation of Biodegradation Rates and Pathways of High Volume Surfactants in the Sewer System." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1439301189.

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11

Merrett, Greg Lee. "Groundwater redox conditions at a petroleum contaminated site, Kuils River, South Africa : pathways for BTEX biodegradation." Master's thesis, University of Cape Town, 2003. http://hdl.handle.net/11427/8588.

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Includes bibliographical references (leaves 84-88).<br>A shallow sandy aquifer, contaminated by petrol from an underground storage tank, was studied to determine if intrinsic bioremediation of the hydrocarbons is taking place. Groundwater samples taken from 32 monitoring wells were analysed for NO₃-,NH₄+, Mn²+, Fe²+, SO₄²-, and ΣH₂S. Portable electrodes were used to make field measurements of electrical conductivity, redox potential, and pH. The variation and distribution of these redox-sensitive groundwater constituents show that bioremediation via NO₃- reduction, Fe³+ reduction, and SO₄²- re
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12

Montgomery-Brown, John. "Elucidating the biodegradation pathways of alkylphenol polyethoxylate metabolites in potable and non-potable water reuse systems /." May be available electronically:, 2007. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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13

Ulbricht, Juliane [Verfasser], and Robert [Gutachter] Luxenhofer. "Insights into Polymer Biodegradation - Investigations on oxidative, hydrolytic and enzymatic Pathways / Juliane Ulbricht ; Gutachter: Robert Luxenhofer." Würzburg : Universität Würzburg, 2018. http://d-nb.info/1154686825/34.

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14

Lan, Renny Shang-Lun. "Pathway and enzymology of cyclic ether biodegradation by Mycobacterium vaccae JOB5." 2006. http://www.lib.ncsu.edu/theses/available/etd-12212006-134444/unrestricted/etd.pdf.

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15

Gitiafroz, Roya. "Microorganisms and Metabolic Pathways Involved in Anaerobic Benzene Biodegradation under Nitrate-reducing Conditions." Thesis, 2012. http://hdl.handle.net/1807/32720.

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This thesis describes the characterization of benzene-degrading denitrifying cultures. Four objectives were pursued. The first objective was to identify conditions that promote or inhibit benzene decomposition and thus, to improve the biodegradation capacity of the cultures. FeS, resazurin, and nitrite had a detrimental impact on benzene degradation, whereas addition of supernatant from an active culture improved the benzene degradation activity by reducing the lag times. The second objective was to determine the microbial community composition in enrichment cultures and to identify the ba
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16

Bains, Jasleen. "Structural and functional characterization of a hybrid benzoate degradation pathway." Thesis, 2011. http://hdl.handle.net/1828/3640.

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Aromatic compounds comprise approximately one quarter of the Earth's biomass and thus play a critical role in the biogeochemical carbon cycle. These compounds are degraded almost exclusively by specialized microbial enzymes that are part of complex metabolic pathways. Detailed characterization of these enzymes is both a gateway to understanding a biological process fundamental to nature and a platform for bioengineering applications in bioremediation. Recently, a novel pathway was shown to metabolize two key aromatic intermediates: Benzoate and Benzoyl-Coenzyme A. Designated as the box pathway
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17

Ulbricht, Juliane. "Insights into Polymer Biodegradation - Investigations on oxidative, hydrolytic and enzymatic Pathways." Doctoral thesis, 2018. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-158683.

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The present work aims towards the investigation of polymer degradation under biologically relevant conditions. In order to assess a potential degradation of polymers of interest for biomedical applications in vivo and associated effects on living tissue, representatives of poly(2-oxazoline)s and polypeptoids as well as poly(ethylene glycol) and poly(N-vinylpyrrolidone) for reference purposes are examined regarding their stability under oxidative and hydrolytic conditions as well as towards enzymatic degradation. The polymers investigated in the framework of this thesis are generally considered
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18

Bessa, Vânia Sofia de Sousa. "Carbamazepine and diclofenac : biodegradation, metabolic pathways and fate in aerobic granular sludge reactors." Doctoral thesis, 2020. http://hdl.handle.net/10400.14/32240.

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The widespread occurrence of various types of emerging contaminants (ECs) has become an issue of high concern. Among ECs, pharmaceuticals and its metabolites deserve particular attention as their presence, continuous release and persistence in water bodies pose serious health issues affecting the entire ecosystem. It is important to understand the biodegradation of such molecules to devise strategies to avoid dispersal of these ECs in the environment. The work described in this thesis aimed at investigating of the microbial degradation of two pharmaceutical compounds, carbamazepine (CBZ) and d
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19

Lamberti, Kelvin Robert. "Endoplasmic reticulum associated degradation (ERAD) overflow pathways." Thesis, 2008. http://hdl.handle.net/10413/10839.

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Accumulation of misfolded proteins in the endoplasmic reticulum (ER) causes numerous human pathologies. Biochemical evidence suggests that soluble misfolded proteins are retrotranslocated out of the ER, via the endoplasmic reticulum associated degradation (ERAD) pathway, for proteosome-mediated cytoplasmic degradation. Excess, misfolded- or insoluble proteins, are suggested to cause induction of “overflow” degradation pathways. For soluble proteins, overflow to vacuole-mediated destruction is suggested to occur via two Golgi-to-vacuole (Gvt) routes, the alkaline phosphatase (ALP), direct route
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20

Gallagher, Erin Maureen. "Anaerobic degradation of 2,4,6- trinitrotoluene (TNT) molecular analysis of active degraders and metabolic pathways /." 2010. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.000052111.

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21

Rajendran, Ranjith Kumar, and 古瑞杰. "Biodegradation of the endocrine disrupter octylphenol by fungi from the environment and its proposed metabolic pathways." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/07597457491199946579.

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博士<br>國立中央大學<br>生命科學系<br>105<br>4-t-Octylphenol (4-t-OP) is a common biotransformation product of the widely used nonionic surfactants, octylphenol polyethoxylates (OPEOn). However, compared to the parent compound that has been extensively used in many industrial sectors including textile, petroleum, paper, and plastic industries, 4-t-OP is known to be more persistent, ubiquitous in the environment, and estrogenically active. Microbial biodegradation is one of the most important natural processes which can influence the fate and removal of pollutants in both aquatic and terrestrial environment
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22

Rutkevich, Lori Ann. "Disulfide Bond Formation: Identifying Roles of PDI Family Thiol Oxidoreductases and ER Oxidant Pathways." Thesis, 2012. http://hdl.handle.net/1807/34871.

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Protein disulfide isomerases (PDIs) catalyze the oxidation and isomerization of disulfide bonds in proteins passing through the endoplasmic reticulum (ER). Although as many as 20 enzymes are classified as PDI family members, their relative contributions to protein folding have remained an open question. Additionally, Ero1 has been characterized as the ER oxidase that transfers oxidizing equivalents from oxygen to PDI enzymes. However, knockout mice lacking the mammalian Ero1 isoforms, Ero1Lα and Ero1Lβ, are viable, and the role of other potential ER oxidases in maintaining an oxidative ER e
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23

Alexandrino, Diogo Alves da Mota. "Microbial degradation of persistent fluorinated pesticides - understanding the microbial dynamics and catabolic pathways associated with the biodegradation of epoxiconazole and fludioxonil." Doctoral thesis, 2022. https://hdl.handle.net/10216/140679.

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24

Kim, Myung Hee 1982. "Factors Affecting Biodefluorination of Fluorotelomer Alcohols (FTOHs): Degradative Microorganisms, Transformation Metabolites and Pathways, and Effects of Co-substrates." Thesis, 2012. http://hdl.handle.net/1969.1/148234.

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Fluorotelomer alcohols (FTOHs, F(CF2)nCH2CH2OH) are emerging contaminants in the environment. Biodegradation of 6:2 and 8:2 FTOHs has been intensively studied using soils and activated sludge. However, little is known about the bacteria responsible for biotransformation of FTOHs. This study deciphered factors affecting biodefluorination of FTOHs and their metabolites, and developed three effective FTOH-degrading consortia. Two alkane-degrading Pseudomonas strains (P. oleovorans and P. butanovora) can defluorinate 4:2, 6:2 and 8:2 FTOHs, with a higher degree of defluorination for 4:2 FTOH.
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