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Dissertations / Theses on the topic 'Biofilm development'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Spenceley, Hazel. "Bacterial attachment and biofilm development." Thesis, University of Warwick, 1993. http://wrap.warwick.ac.uk/73521/.

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Initial work involved the isolation and characterization of bacteria found on the surfaces in a range of food processing environments. The attachment characteristics of three species of bacteria (S.liquefaciens, S.cohnii and P.fragi) isolated from the same production surface were examined. Mixed culture biofilm development was also modelled using these three organisms. The species were found to have differing attachment abilities and therefore cell surface characteristics such as outer membrane protein and lipopolysaccharide profiles, exopolysaccharide production, and cell surface hydrophobici

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2

Ulfenborg, Benjamin. "Investigation of the implications of nitric oxide on biofilm development." Thesis, University of Skövde, School of Life Sciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-3195.

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<p>Biofilms are communities of sessile microorganisms attached to a surface and imbeddedin a matrix of extracellular polysaccharide substances. These communities can be foundin diverse aquatic environments, such as in industrial pipes and in humans. By formingmicrocolony structures, which are highly resistant to adverse physical conditions as wellas antimicrobial agents, biofilms are very problematic when associated with e.g.persistent infections. In order to find new ways of controlling biofilm growth, theprocesses involved in biofilm development must be investigated further. The maininterest

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3

Alamri, Hadi M. "Antimicrobial efficacy of different calcium hydroxide containing preparations against biofilms at different stages of biofilm development." Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/55988.

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Objective: To quantify and assess the antibacterial effect of different medicaments on young and aged biofilms, and to modify the medicaments in order to increase their antibacterial effect. Hypotheses: Microbes in aged biofilms grown from a mixture of oral bacteria are more resistant to the antimicrobial activity of calcium hydroxide than microbes in young biofilms. Biofilms are less resistant to calcium hydroxide combined with other antimicrobial agents than to pure calcium hydroxide. Methodology: Collagen coated hydroxyapatite disks were immersed in plaque suspension solution and incubate

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4

McFarlane, Alexander. "Biofilm development and management in aircraft fuel systems." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/17655/.

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5

Martin, G. C. "Development of an orally relevant biofilm disinfection model." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1346469/.

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This thesis describes the development and use of a novel microtitre plate biofilm system for testing the antimicrobial activity of test materials. The developed model is capable of high-throughput screening and furthermore the system has been shown to be stable and reproducible. The search for new antimicrobial agents for improved plaque control requires appropriate screening models. Key criteria for these models include; predictive of clinical data, orally relevant organisms (mixed species, bacteria present in biofilms), short contact time, rapid, reproducible and high throughput. The most wi

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6

Marais, Susara. "Characterization of the early stages in biofilm development." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/49880.

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Thesis (MSc)--Stellenbosch University, 2004.<br>ENGLISH ABSTRACT: Complex biofilm communities have extensively been studied in the past. Less work has been done on the early stages of biofilm formation. This study aimed to assess initial colonization patterns of biofilms on different surfaces and under different environmental conditions with application of novel methods describing biofilm surface profiles. Biofilms were cultivated on glass, polyvinylchloride (PVC) and polished stainless steel. Results from microscopy, followed by mathematical analysis and contact angle measurements prove

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7

Petrova, Olga E. "Stage-specific regulation of Pseudomonas aeruginosa biofilm development." Diss., Online access via UMI:, 2009.

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8

Al-Radha, Afya Sahib Diab. "Surface properties and biofilm development associated with dental implants." Thesis, University of Bristol, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.682353.

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The use of titanium dental implants in oral rehabilitation has been shown to have a high success rate, Despite this fact, failures do occur, One of the causes of implant failure is peri-implantitis. The aim of this research was to investigate the effect of different surface modifications on titanium surface characteristics, and to explore if one or more of these surface characteristics or antimicrobial agents can reduce microbial adhesion and biofilm formation. Also, to identify major bacterial species associated with peri-implant diseases in human subjects. A variety of chemical and physical

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9

Dibelka, James. "MATERNAL INFLUENCES ON THE DEVELOPMENT OF INFANT ORAL BIOFILM." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/2457.

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Purpose: The purpose was to examine the maternal influences on the development of infant oral biofim and dominant bacterial strains of at risk populations. Methods: The study used a cross-sectional design to examine factors influencing biofilm colonization and the identification of bacterial strains transmitted from mother to child. Participants were enrolled in Children’s Health Involving Parents of Greater Richmond (CHIP). Plaque and saliva samples were collected from mothers and their children ages 6-36 months. The colonized oral bacteria strains of the mother infant dyads were then c

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10

Haggarty, Jennifer. "Biofilm metabolomics : the development of mass spectrometry and chromatographic methodology for the analysis of dual-species pathogenic biofilms." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8616/.

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Polymicrobial diseases arise when multiple microorganisms colonize a host and form multi-species biofilms. Within polymicrobial communities bacteria, fungi, viruses and/or parasites directly and indirectly interact with one another in a multitude of ways. The composition and the interactions between organisms within polymicrobial biofilms govern disease severity and patient outcomes. Polymicrobial infections are of significant interest because of the escalating development of antimicrobial resistance and the increasing involvement polymicrobial biofilms in chronic and systemic infections. The

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11

Thein, Zaw Moe. "The impact of the oral environment on Candida biofilm development." Thesis, Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B3931859X.

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12

Cantillon, Daire. "Development and characterisation of a low-shear mycobacterial biofilm model." Thesis, University of Brighton, 2017. https://research.brighton.ac.uk/en/studentTheses/2a58b09f-1333-449f-9c72-d44011877211.

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Tuberculosis (TB) is a bacterial disease that primarily affects the lungs and is caused by the bacillus Mycobacterium tuberculosis (M.tb). Approximately 1 in 3 people are latently infected globally, with 1.5 million people dying from active TB in 2015 alone. Prolonged therapy of at least six months with four antimicrobial drugs is required to successfully treat disease. This lengthy drug treatment is necessary to remove sub-populations of M.tb that are tolerant to antimicrobial drugs and as a result persist through drug therapy. Despite the hypothesised clinical significance of drug tolerant M

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13

Salauddin, Hasan Shahariar. "Development of techniques for quantitative biofilm assay and isolation and characterization of an E. Coli gene involved in biofilm maturation." Thesis, Heriot-Watt University, 2008. http://hdl.handle.net/10399/2034.

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In their natural habitat bacteria predominantly exist as biofilms in which bacteria differ physiologically and metabolically from free-living cells. The aim of the study was to identify and characterize genes that are involved in biofilm maturation. The crystal violet (CV) assay is widely used to identify early stage biofilm mutants. However, it is not sufficiently sensitive to isolate late stage mutants that fail to develop mature biofilms. Using tetrazolium salt XTT (sodium 3'-{ l-[(phenylamino)-carbonyl]-3,4tetrazolium}- bis (4- methoxy-6-nitro) benzenesulfonic acid hydrate) this study ther

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14

Leech, James Thomas. "Development of an Escherichia coli biofilm platform for use in biocatalysis." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8055/.

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Biocatalysis processes use biologically-derived enzymes to perform fine-chemical synthesis. Whole-cell biocatalysis, using live microorganisms, offers protection against buffer conditions and denaturation, and allows turnover of effective enzymes. However, cells may still be damaged by reaction conditions. In nature, cell populations protect themselves by attaching to surfaces and producing a multi-component protective extracellular matrix. This multicellular mode of growth is termed a biofilm. Biofilms offer many advantages over individual free-floating cells which may be beneficial in whole-

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15

Santos, Tiago. "Role of proteome in biofilm development and adaptation of Listeria monocytogenes to controlled environments." Thesis, Université Clermont Auvergne‎ (2017-2020), 2019. http://www.theses.fr/2019CLFAC027/document.

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Listeria monocytogenes est une bactérie à Gram positif impliquée dans des infections graves d’origine alimentaire. La plupart des cas de listériose humaine sont causés par la consommation d'aliments réfrigérés prêts à consommer. La capacité de ces bactéries à survivre et à se multiplier dans une large gamme de conditions difficiles fait de ce pathogène une des préoccupations majeures dans les industries agro-alimentaires. Ces propriétés de L. monocytogenes sont renforcées par son aptitude à former des biofilms. Le but de ce projet était d'explorer l'adaptation de ce pathogène à la déshumidific

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16

Chao, Yuanqing, and 晁元卿. "Studies of biofilm development by advanced microscopic techniques and high-throughput sequencing." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B50899922.

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This study was conducted to investigate the biofilm formation by using advanced microscopic and high-throughput sequencing techniques. The major tasks were (1) to quantitatively evaluate the initial bacterial attachment processes by Atomic Force Microscopy (AFM); (2) to characterize the chemical variation during biofilm formation by Raman microscopy; (3) to analyze the microbial structure and functions in the wastewater and drinking water biofilms by metagenomic analysis. To determine the lateral detachment force for bacteria, a quantitative method using contact mode of AFM was developed.

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17

Fischer, Matthias [Verfasser]. "Marine biofilm formation dynamics – from sensor development to field applications / Matthias Fischer." Kiel : Universitätsbibliothek Kiel, 2013. http://d-nb.info/1045603961/34.

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18

Radianingtyas, Helia. "Development of a biofilm reactor process for the treatment of 4-chloroaniline." Thesis, University of Kent, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314266.

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19

Ramos, Martínez Eva. "Assessing biofilm development in drinking water distribution systems by Machine Learning methods." Doctoral thesis, Universitat Politècnica de València, 2016. http://hdl.handle.net/10251/63257.

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[EN] One of the main challenges of drinking water utilities is to ensure high quality supply, in particular, in chemical and microbiological terms. However, biofilms invariably develop in all drinking water distribution systems (DWDSs), despite the presence of residual disinfectant. As a result, water utilities are not able to ensure total bacteriological control. Currently biofilms represent a real paradigm in water quality management for all DWDSs. Biofilms are complex communities of microorganisms bound by an extracellular polymer that provides them with structure, protection from toxics an

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20

Abdulgader, Mohamed E. Essa. "Development of Flexible Fibre Biofilm Reactors for Treatment of Milk Processing Wastewater." Thesis, Griffith University, 2011. http://hdl.handle.net/10072/366653.

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Food processing industries use considerable amounts of fresh water for their industrial purposes. These industries generate large quantities of high strength organic wastewaters which are usually biodegradable and amenable to biological treatment systems. Numbers of biological methods are still in use for the treatment of food processing wastewaters, either anaerobic or aerobic systems. In this research, the performance using newly developed laboratory scale sequencing batch flexible fibre biofilm reactor (SB-FFBR), single stage flexible fibre biofilm reactor (SS-FFBR) and newly developed mul

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21

Stacey, Rachael. "The role of the Pseudomonas aeruginosa galactophilic lectin PA-IL in biofilm development." Thesis, University of Nottingham, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415615.

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22

Gunn, N. "Marine biofilm development on titanium with particular reference to seawater heat exchange systems." Thesis, University of Portsmouth, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234641.

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23

Chittezham, Thomas Vinai. "The molecular control and biological implications of autolysis in enterococcus faecalis biofilm development." Diss., Manhattan, Kan. : Kansas State University, 2009. http://hdl.handle.net/2097/1519.

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24

McMath, Sarah Michelle. "The development and control of biofilm and planktonic communities in potable water distribution systems." Thesis, University of Surrey, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265656.

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25

Zarabadi, Mirpouyan. "Development of a robust microfluidic electrochimical cell for biofilm study in controlled hydrodynamic conditions." Doctoral thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/35734.

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Le domaine de la bioélectrochimie a actuellement un grand impact sur les nouvelles biotechnologies, notamment les dispositifs médicaux aux points de service et la détection bioélectrochimique. D'autre part, les systèmes émergents de bioénergie offrent de nouvelles opportunités pour se passer des produits pétroliers classiques grâce à des approches alternatives plus durables sur le plan environnemental. En tant que telle, la branche de la bioélectrochimie traitant des systèmes énergétiques est sur le point d’avoir un impact incontestable sur les concepts d’énergie verte et de bioénergie. Pour f

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26

Lee, Woo Hyoung. "Development and Use of Microelectrodes to Evaluate Nitrification within Chloraminated Drinking Water System Biofilms, and the Effects of Phosphate as a Corrosion Inhibitor on Nitrifying Biofilm." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1258489526.

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27

King, Andrew D. "The role of contact-dependent growth inhibition toxin systems in bacterial competition and biofilm development." Thesis, University of York, 2015. http://etheses.whiterose.ac.uk/10571/.

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Contact-dependent growth inhibition (CDI) toxins are a recently identiﬁed family of polymorphic toxins, initially found in Escherichia coli. CDI toxins are found widely spread in Gram-negative bacterial species, including pathogenic strains, and have been shown to possess a wide range of toxin types which are effective against other bacteria. This research shows that the E. coli EC93 CDI system confers a competitive advantage on bacteria growing in multi strain bioﬁlms with susceptible bacteria. This advantage is due to two factors, ﬁrstly the EC93 CDI toxin was shown to be capable of inhibiti

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28

King, Allison. "DEVELOPMENT OF NOVEL COPOLYOXETANES: ANTIMICROBIAL AGENTS." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/293.

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This thesis focuses on solution antimicrobial effectiveness for copolyoxetanes with quaternary ammonium and PEG-like side chains. Ring opening copolymerization of 3-((4-bromobutoxy)methyl)-3-methyloxetane (BBOx) and 3-((2-(2-methoxyethoxy) ethoxy) methyl)-3-methyloxetane (ME2Ox) yielded random copolymers with 14-100 (m) mole% BBOx designated P[(BBOx-m)(ME2Ox)]. Reaction of P[(BBOx-m)(ME2Ox)] with dodecyl dimethylamine gave the corresponding quaternary P[(C12-m)(ME2Ox)] polycation salts, designated C12-m. Mole ratios and molecular weights were obtained from 1H-NMR and end group analysis. Differ

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29

Feng, Monica. "Properties and development of Mycoplasma pneumoniae biofilms in relation to persistence and cytotoxicity." Miami University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=miami1565869297815629.

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30

Iyer, Vijayalakshmi Subramanian. "Role of the transcription regulator RpoN (sigma 54) in Enterococcus faecalis biofilm development, metabolism and virulence." Diss., Kansas State University, 2012. http://hdl.handle.net/2097/17150.

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Doctor of Philosophy<br>Department of Biology<br>Lynn Hancock<br>Enterococci are the third leading cause of nosocomial infections including urinary tract infections (UTI), surgical site infections (SSI) and blood stream infections. Enterococci are also found in the gastrointestinal tracts of humans, and other mammals. We elucidated the influence of the transcriptional regulator RpoN on enterococcal biofilm formation, virulence potential and cell wall architecture and proposed a potential involvement for carbohydrate metabolism in these processes. Biofilms are held together by matrix (BM) comp

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31

Okaro, Udoka. "A Small RNA and DNA Binding Protein Contribute to Biofilm Development in Bartonella henselae." Scholar Commons, 2019. https://scholarcommons.usf.edu/etd/7878.

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A biofilm, which is associated with 80% of chronic infections in humans, is formed when bacteria aggregate, attach to a substrate and secrete a matrix protecting the bacteria from host cell defenses and antibiotics. Bartonella henselae (B. henselae) is the causative agent of cat scratch disease, persistent bacteremia, and one of the most frequently reported causes of blood-culture negative endocarditis (BCNE) in patients. The ability of B. henselae to adhere to the heart valve, form a biofilm and vegetation to cause endocarditis increases the morbidity and mortality rate in infected patients.

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Peterson, Benjamin L. "Development and Optimization of a Produced Water, Biofilm Based Microalgae Cultivation System for Biocrude Conversion with Hydrothermal Liquefaction." DigitalCommons@USU, 2018. https://digitalcommons.usu.edu/etd/7237.

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Extraction of oil and gas in Utah’s Uintah Basin results in large quantities of wastewater, or produced water, with nutrients and residual organic chemical that represent a significant resource for producing energy-related and value-added products. Produced water was obtained as a biomass producing nutrient source from industries operating in Utah’s Uintah Basin. Within the Uintah Basin (defined as Uintah and Duchesne Counties within Utah) approximately 93 million barrels of water were produced in 2013 while only 11% of the water was disposed of through evaporation, with the national average a

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33

Hage, Mayssane. "Understanding the mechanisms of interactions at interfaces between bacteria and materials : development of anti-adhesion and anti-biofilm surfaces." Electronic Thesis or Diss., Université de Lille (2018-2021), 2021. http://www.theses.fr/2021LILUR037.

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L’environnement opératoire dans les domaines alimentaire et médical permet aux bactéries de se fixer et de se développer sur les surfaces, ce qui entraîne la formation de biofilms bactériens pathogènes et résistants. Ces structures pathogènes sont responsables de plusieurs maladies d'origine alimentaire et d'infections nosocomiales. Par conséquent, pour lutter contre ce fléau de santé publique, une approche possible est l'utilisation des technologies plasma froid pour l’élaboration de revêtements sur différents matériaux. Ce travail présente les différents facteurs influençant l'adhésion bacté

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34

Luo, Hongliang. "Identification of microorganisms in food ecosystems and characterization of physical and molecular events involved in biofilm development." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1133304823.

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35

MacLeod, Sarah M. "Study of the factors that modulate the rate of crystalline Proteus mirabilis biofilm development on urinary catheters." Thesis, Cardiff University, 2006. http://orca.cf.ac.uk/56157/.

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Around 50% of patients enduring long-term catheterisation experience encrustation and blockage of their catheters. This problem stems from infection by urease producing bacterial species, in particular Proteus mirabilis. The urease enzyme hydrolyses urea to carbon dioxide and ammonia which elevates the urinary pH. Under these alkaline conditions crystals of calcium and magnesium phosphates form and the crystalline bacterial biofilm that develops on the catheter can eventually block the flow of urine through its lumen. Catheter blockage in this way can induce complications that put the health o

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36

Malcolm, Jennifer. "Development of the cariogenic oral biofilm coincident with the evolution of immune responses in very young children." Thesis, University of Glasgow, 2013. http://theses.gla.ac.uk/4082/.

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Dental caries remains one of the most common chronic infectious childhood diseases and individuals remain susceptible to the disease throughout their lifetime. The disease continues to inflict a substantial economic burden. Moreover, dental caries demonstrates considerable socioeconomic disparities with the lowest socioeconomic groups suffering the greatest burden of disease. There is an unmet need to improve prevention and therapeutics and yet there remain fundamental gaps in the knowledge of the interrelationships between caries-associated risk factors, in particular how the immune system in

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37

Elmanaseer, Wijdan Radwan. "Investigation of silver enhanced dental restorative materials by the development of an in vitro oral biofilm model." Thesis, University of Dundee, 2018. https://discovery.dundee.ac.uk/en/studentTheses/ee764157-bdaa-4407-b4ee-92093c89c3f8.

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Generally, in vitro oral biofilm models are commonly used to help in understanding the complex processes and the factors affecting oral diseases. They help to accurately predict, in a controlled and simplified way, a clinical outcome which can lead us to preventive actions for a disease (Salli and Ouwehand, 2015).The complexity of biofilm research requires different approaches to address various questions. Furthermore, models cannot capture all of the details involved with disease formation, however it is considered a way of performing a reproducible experiment under controlled conditions. Obv

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Lynch, David John. "An analysis of the role of glucan-binding proteins in Streptococcus mutans biofilm architecture and caries development." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/852.

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Tooth decay is a serious health risk and a significant contributor to health care costs in both industrialized and developing nations. Tooth decay is the end result of a change in the balance of plaque ecology towards more acidogenic and aciduric bacterial species. The primary force facilitating this change is an increase in the amount and frequency of simple carbohydrate, in particular, sucrose ingestion by the host. The acidity of plaque increases after host ingestion of fermentable carbohydrates and this promotes demineralization of the tooth enamel which is restored by salivary buffering a

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Monmeyran, Amaury. "Étude expérimentale d’un modèle de biofilm bactérien multi-espèces en vidéo-microscopie : cinétique de formation et interactions entre espèces." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS242.

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Pendant mon travail de thèse, j’ai caractérisé le développement d’un biofilm multi-espèces en canaux milli-fluidiques sous flux constant de milieu nutritif. J’ai tout d’abord mis au point l’utilisation d’un nouveau rapporteur fluorescent sur un biofilm d’Escherichia coli. J’ai montré les limites des rapporteurs classiques de type GFP sur le système et introduit la protéine FAST à fluorescence inductible pour les dépasser. Avec ce nouvel outil, j’ai ensuite étudié la formation d’un biofilm multi-espèces, issu d’un biofilm naturel adapté au laboratoire, constitué de Bacillus thuringiensis (Bt),

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Hosseinidoust, Zeinab. "An investigation of bacteriophage-bacteria interactions: development of phage resistance and associated variations in virulence and biofilm formation." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114443.

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The rise of antibiotic resistance has rekindled interest in the development of alternative antimicrobial agents. Bacteriophages, bacteria's obligate parasites, have drawn a lot of interest from the scientific community and from the industry due to their many advantages. However, there are various challenges hindering the use of bacteriophages as antimicrobial agents. In this dissertation, a number of these challenges have been addressed. After a brief introduction on the advantages and drawbacks of using phage in chapter one, the inherent limitation of using immobilized phage for antimicrobial

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Sriwiriyarat, Tongchai. "Computer Program Development for the Design of IFAS Wastewater Treatment Processes." Thesis, Virginia Tech, 1999. http://hdl.handle.net/10919/32065.

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The Integrated Film Activated Sludge Process (IFAS) was developed to reduce the cost of additional facilities required to complete year round nitrification in the design of new or retrofit wastewater treatment plants. The purpose of this project was to develop a computer-based mechanistic model, called IFAS, which can be used as a tool by scientists and engineers to optimize their designs and to troubleshoot a full-scale treatment plant. The program also can be employed to assist researchers conducting their studies of IFAS wastewater treatment processes. IFAS enables the steady-state simulati

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Ju, Minseon. "Development of nanoparticle probes for magnetic particle spectrometry and thermal applications." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1619708980426229.

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McCall, Stephanie Jane. "Investigating the effects of nutrient concentration and light intensity on benthic biofilm development and phytoplankton growth in UK rivers." Thesis, University of Portsmouth, 2014. https://researchportal.port.ac.uk/portal/en/theses/investigating-the-effects-of-nutrient-concentration-and-light-intensity-on-benthic-biofilm-development-and-phytoplankton-growth-in-uk-rivers(5bb096f7-b9fb-4a4f-a714-e2f05271800d).html.

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Phosphorus is often considered the limiting nutrient in rivers, and reducing concentrations has long been a key policy focus. However, experience has shown that many phosphorus mitigation schemes fail to achieve any improvements in ecological status. The primary aim of this thesis is to identify target phosphorus concentrations that need to be attained to improve river ecology. In-stream flume mesocosms were deployed on three UK rivers of varying levels of nutrient enrichment. Phosphorus concentrations were simultaneously increased and decreased (by iron-dosing) to provide a concentration grad

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Baker-Moffatt, Michelle. "Examining biofilm development within fine-bore nasogastric tubes used by adults and exploring the nursing perspective of tube management." Thesis, University of Southampton, 2017. https://eprints.soton.ac.uk/417340/.

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The consequences of malnutrition are wide ranging, making it an important patient safety issue. Enteral tube feeding can support adults unable to meet their nutritional requirements through oral intake, with fine bore nasogastric tubes preferred for patient comfort. Over a third of nasogastric tubes in use block, resulting in compromised nutrient provision and poor patient experience. Biofilm can interrupt fluid flow through indwelling devices. Evidence of biofilm on the inner surface of nasogastric tubes and its potential to contribute to blockage development had not been investigated. The pu

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Hummerhielm, Linda. "Biolayer development in a slow sand filter in Ghana : Designing a filter that is benefiting the biolayer development under local conditions." Thesis, Karlstads universitet, Fakulteten för hälsa, natur- och teknikvetenskap (from 2013), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-62601.

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In 2015, the United nations presented the 17 Global Goals that would put an end to extreme poverty, inequality and climate change by 2030. One of these goals was clean water and sanitation. In 2015 1.8 billion people did not have access to clean water. Because of the contaminated water, one million people die every year worldwide. Africa, and especially Ghana, has had a high development in the recent years. The population has grown and more resources are needed. Clean water in Ghana is not a given matter, three million people live without access to clean water. To work towards the Global Goal

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Manuzon, Michele Yabes. "Investigation of Pseudomonas Biofilm Development and Removal on Dairy Processing Equipment Surfaces Using Fourier Transform Infrared (FT-IR) Spectroscopy." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1253576498.

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Crowther, Grace. "Development and characterisation of an in vitro human gut model to study the biofilm mode of growth of Clostridium difficile and the indigenous gut microbiota." Thesis, University of Leeds, 2013. http://etheses.whiterose.ac.uk/5736/.

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Abstract:

Clostridium difficile infection (CDI) is associated with significant patient morbidity, mortality and financial burden. Until recently, antimicrobial treatment options were limited to metronidazole and vancomycin, but both agents are associated with recurrence rates of approximately 20%. The human gastrointestinal tract harbours a complex microbial community which exist in planktonic and sessile form. Sessile organisms are known to cause chronic infection such as cystic fibrosis. Mucosal biofilms exist on surfaces of the gastrointestinal tract, but the existence and role of C. difficile in the

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Smith, Francis Lee. "Pilot-scale Development of Trickle Bed Air Biofiltration Employing Deep Biofilms, for the Purification of Air Polluted with Biodegradable VOCs." University of Cincinnati / OhioLINK, 1999. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1034206999.

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SCIANO', Fabio. "Development of natural and synthetic compounds as kinase inhibitors targeting cancer cells and cancer stem cells." Doctoral thesis, Università degli Studi di Palermo, 2023. https://hdl.handle.net/10447/580156.

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Sequira, Saannya. "Structural studies of a novel adhesin involved in host-specific Lactobacillus reuteri biofilm formation in the vertebrate gastrointestinal tract, and, Purification method development for structural studies of WaaP : an essential gram-negative bacteria lipopolysaccharide kinase." Thesis, University of East Anglia, 2016. https://ueaeprints.uea.ac.uk/65623/.

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Abstract:

In vertebrates, strains of the gut symbiont, Lactobacillus reuteri, form biofilms on the proximal gastric stratified epithelium in a host-dependent manner. The gene for a novel serine-rich repeat (SRR) adhesin, conserved amongst rat and porcine L. reuteri, is essential for successful biofilm formation, suggesting initial adhesion to be the most crucial step for colonisation, and a possible driver of host-specificity. High resolution crystal structures of the partial binding regions (BR) of two SRR adhesins, BR55 and BR78, from porcine L. reuteri ATCC 53608 and rodent L. reuteri 100-23 strains,

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