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Relevant bibliographies by topics / BioFire® FilmArray® Torch System

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Journal articles

Academic literature on the topic 'BioFire® FilmArray® Torch System'

Author: Grafiati

Published: 29 June 2021

Last updated: 11 February 2022

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Journal articles on the topic "BioFire® FilmArray® Torch System"

1

Toxopeus, Corike, Brian Jones, Jessica Brown, Mark Gurling, Cynthia Andjelic, and Cynthia L. Phillips. "422. Performance Evaluation of a Rapid and Easy-to-Use COVID-19 Test." Open Forum Infectious Diseases 7, Supplement_1 (2020): S278. http://dx.doi.org/10.1093/ofid/ofaa439.616.

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Abstract Background The BioFire® COVID-19 Test is a qualitative test for use on the FilmArray® 2.0 and Torch systems for the detection of SARS-CoV-2 RNA in nasopharyngeal swabs (NPS) in transport media. This test received Emergency Use Authorization from the FDA. A closed, disposable pouch contains all the necessary reagents for sample preparation, nucleic acid extraction, reverse transcription, polymerase chain reaction (PCR), and amplified nucleic acid detection to identify RNA from SARS-CoV-2 virus in an NPS specimen. Internal controls monitor all stages of the test process. Once an NPS sam

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2

Helm, Jared R., Brian Jones, Corike Toxopeus, et al. "1221. Evaluation of the FilmArray® Global Fever Panel." Open Forum Infectious Diseases 7, Supplement_1 (2020): S631—S632. http://dx.doi.org/10.1093/ofid/ofaa439.1406.

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Abstract Background Acute Febrile Illness (AFI) is caused by a diverse set of pathogens. The FilmArray Global Fever (GF) Panel, developed by BioFire Defense in collaboration with the U.S. Department of Defense and NIAID, uses an automated, multiplex nested PCR system to evaluate whole blood samples for multiple pathogens simultaneously in under an hour. Methods BioFire Defense conducted analytical performance studies to show sensitivity (LoD), inclusivity, and specificity (exclusivity), and a prospective clinical study to evaluate the positive percent agreement (PPA) and negative percent agree

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3

Green, Jeremy, Caitlin Carter, Craig Chandler, Angela Clark, and Stephanie Thatcher. "1015. Enhanced Detection of Bloodstream Pathogens From Positive Blood Culture Specimens With an Improved Multiplex PCR Molecular Diagnostic System." Open Forum Infectious Diseases 5, suppl_1 (2018): S302. http://dx.doi.org/10.1093/ofid/ofy210.852.

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Abstract Background Timely bloodstream infection (BSI) pathogen identification requires robust sample purification and testing methods that can accommodate the wide variety of blood culture media used for growing positive blood culture (PBC) specimens. Sensitive molecular methods are needed for identification of all organisms present in PBD, especially polymicrobial cultures which can be difficult to identify with standard methods. Multiple types of BD and BioMérieux blood culture media commonly used in hospital laboratories were used to evaluate the performance of a prototype BioFire® FilmArr

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4

Oberhettinger, Philipp, Jan Zieger, Ingo Autenrieth, Matthias Marschal, and Silke Peter. "Evaluation of two rapid molecular test systems to establish an algorithm for fast identification of bacterial pathogens from positive blood cultures." European Journal of Clinical Microbiology & Infectious Diseases 39, no. 6 (2020): 1147–57. http://dx.doi.org/10.1007/s10096-020-03828-5.

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Abstract Fast identification of pathogens directly from positive blood cultures is of highest importance to supply an adequate therapy of bloodstream infections (BSI). There are several platforms providing molecular-based identification, detection of antimicrobial resistance genes, or even a full antimicrobial susceptibility testing (AST). Two of such test systems allowing rapid diagnostics were assessed in this study: The Biofire FilmArray® and the Genmark ePlex®, both fully automated test system with a minimum of hands-on time. Overall 137 BSI episodes were included in our study and compared

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5

Liesman, Rachael M., Angela P. Strasburg, Angela K. Heitman, Elitza S. Theel, Robin Patel, and Matthew J. Binnicker. "Evaluation of a Commercial Multiplex Molecular Panel for Diagnosis of Infectious Meningitis and Encephalitis." Journal of Clinical Microbiology 56, no. 4 (2018): e01927-17. http://dx.doi.org/10.1128/jcm.01927-17.

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ABSTRACT Rapid and accurate laboratory tests are important for the timely diagnosis and treatment of central nervous system infections. The FilmArray meningitis/encephalitis (ME) panel (BioFire Diagnostics, Salt Lake City, UT) is an FDA-cleared, multiplex molecular panel that allows the detection of 14 pathogens (bacterial [n = 6], viral [n = 7], and fungal [n = 1] pathogens) from cerebrospinal fluid (CSF). In this study, we evaluated the performance characteristics of the FilmArray ME panel using clinical, residual CSF samples (n = 291) that tested positive by a routine method(s) (e.g., bacte

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6

Ruzante, Juliana M., Katherine Olin, Breda Munoz, Jeff Nawrocki, Rangaraj Selvarangan, and Lindsay Meyers. "Real-time gastrointestinal infection surveillance through a cloud-based network of clinical laboratories." PLOS ONE 16, no. 4 (2021): e0250767. http://dx.doi.org/10.1371/journal.pone.0250767.

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Acute gastrointestinal infection (AGI) represents a significant public health concern. To control and treat AGI, it is critical to quickly and accurately identify its causes. The use of novel multiplex molecular assays for pathogen detection and identification provides a unique opportunity to improve pathogen detection, and better understand risk factors and burden associated with AGI in the community. In this study, de-identified results from BioFire® FilmArray® Gastrointestinal (GI) Panel were obtained from January 01, 2016 to October 31, 2018 through BioFire® Syndromic Trends (Trend), a clo

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7

Nguyen, Kiet, Lacie McKamey, and Sarah Green. "196. Impact of BioFire FilmArray® Blood Culture Identification on the Management of Staphylococcus aureus Bacteremia." Open Forum Infectious Diseases 6, Supplement_2 (2019): S117. http://dx.doi.org/10.1093/ofid/ofz360.271.

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Abstract Background Staphylococcus aureus bacteremia (SAB) is associated with 30-day mortality rates that are as high as 20 to 40%. In order to reduce mortality and treatment failures, SAB management should include prompt infectious diseases (ID) consult, repeat blood cultures, source control, intravenous antibiotics for the entirety of treatment, and optimal treatment duration. The objective of this study was to determine the impact of BioFire FilmArray® Blood Culture Identification (BCID) on the implementation of these standard of care measures in the management of SAB across a large health

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8

Maves, Ryan, Derek Larson, Michael Dempsey, et al. "Feasibility and Validation of Viral Respiratory Disease Surveillance in a Combat Theater Using the Filmarray Respiratory Panel." Open Forum Infectious Diseases 4, suppl_1 (2017): S360. http://dx.doi.org/10.1093/ofid/ofx163.874.

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Abstract Background Viral respiratory infections are a significant threat to deployed military units. Pathogen-based surveillance may be hampered by limitations in trained personnel in theater, difficulty with specimen shipment, and technical issues with equipment maintenance. In this project, we evaluated the performance of the FilmArray respiratory panel at military clinics in Afghanistan and compare results to testing performed in the United States. Methods Participants were recruited after presenting at military clinics at Bagram Airfield (BAF), Afghanistan, in 2013–2014 with fever (≥38° C

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9

Chen, Lynette, Matthew Pettengill, Bryan Hess, and Joseph DeSimone. "866. Increased Diagnosis of Varicella-Zoster Virus Infection of the Central Nervous System With the BioFire FilmArray Meningitis/Encephalitis Panel." Open Forum Infectious Diseases 5, suppl_1 (2018): S22—S23. http://dx.doi.org/10.1093/ofid/ofy209.051.

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Abstract Background Varicella-zoster virus (VZV) infection of the central nervous system (CNS) is relatively uncommon. Diagnostic tests historically utilized culture, serologies, and targeted PCR methods. In April 2016, our institution began using the BioFire FilmArray meningitis/encephalitis (BFME) panel for cerebrospinal fluid (CSF) specimen analysis. We hypothesized that the diagnosis of VZV CNS infection increased at our institution with the implementation of this diagnostic panel. Methods We conducted chart reviews of patients from 2 time periods. In the first period, April 2013–March 201

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10

Salimnia, Hossein, Marilynn R. Fairfax, Paul R. Lephart, et al. "Evaluation of the FilmArray Blood Culture Identification Panel: Results of a Multicenter Controlled Trial." Journal of Clinical Microbiology 54, no. 3 (2016): 687–98. http://dx.doi.org/10.1128/jcm.01679-15.

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Sepsis is a major cause of morbidity, mortality, and increased medical expense. Rapid diagnosis improves outcomes and reduces costs. The FilmArray blood culture identification panel (BioFire Diagnostics LLC, Salt Lake City, UT), a highly multiplexed PCR assay, can identify 24 etiologic agents of sepsis (8 Gram-positive, 11 Gram-negative, and 5 yeast species) and three antimicrobial resistance genes (mecA,vanA/B, andblaKPC) from positive blood culture bottles. It provides results in about 1 h with 2 min for assay setup. We present the results of an eight-center trial comparing the sensitivity a

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